decabromodiphenyl-ethane and Weight-Loss

Decabromodiphenyl ethane (DBDPE) as a novel brominated flame retardant is frequently detected in environmental media due to its widespread use. Studies have shown that exposure to environmental pollutants in utero could lead to weight loss in newborns and obesity in adulthood. However, the mechanisms of how the cubs grow rapidly from low birth weight to obesity remain unclear. Although it has been reported that perinatal DBDPE exposure caused obesity in the offspring of mice in adulthood, its metabolic changes in offspring juvenile are unknown. Here, we monitored changes of body weight in cubs following exposure to DBDPE in utero. Furthermore,

Topics: Animals; Bromobenzenes; Environmental Pollutants; Female; Flame Retardants; Glycogenolysis; Halogenated Diphenyl Ethers; Lipids; Mice; Obesity; Pregnancy; Weight Loss