debromohymenialdisine and Neoplasms

debromohymenialdisine has been researched along with Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for debromohymenialdisine and Neoplasms

Article	Year
Synthesis and CHK1 inhibitory potency of Hymenialdisine analogues. Bioorganic & medicinal chemistry letters, 2009, Feb-01, Volume: 19, Issue:3 A series of thieno[3,2-b]pyrroloazepinones derivatives related to Hymenialdisine were prepared and tested for CHK1 inhibitory activity. Nanomolar inhibitions were achieved when electron-withdrawing substituents were introduced at position 3 of the thiophene ring. Topics: Antineoplastic Agents; Azepines; Checkpoint Kinase 1; Chemistry, Pharmaceutical; Drug Design; Drug Screening Assays, Antitumor; Electrons; Humans; Inhibitory Concentration 50; Models, Chemical; Molecular Structure; Neoplasms; Protein Kinases; Pyrroles; Structure-Activity Relationship; Thiophenes	2009

Article

Year

Synthesis and CHK1 inhibitory potency of Hymenialdisine analogues.

Bioorganic & medicinal chemistry letters, 2009, Feb-01, Volume: 19, Issue:3

A series of thieno[3,2-b]pyrroloazepinones derivatives related to Hymenialdisine were prepared and tested for CHK1 inhibitory activity. Nanomolar inhibitions were achieved when electron-withdrawing substituents were introduced at position 3 of the thiophene ring.

Topics: Antineoplastic Agents; Azepines; Checkpoint Kinase 1; Chemistry, Pharmaceutical; Drug Design; Drug Screening Assays, Antitumor; Electrons; Humans; Inhibitory Concentration 50; Models, Chemical; Molecular Structure; Neoplasms; Protein Kinases; Pyrroles; Structure-Activity Relationship; Thiophenes

2009