debrisoquin has been researched along with Precursor Cell Lymphoblastic Leukemia-Lymphoma in 1 studies
Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
Precursor Cell Lymphoblastic Leukemia-Lymphoma: A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Food intake reduced the time to peak concentration both in plasma, from 1." | 1.28 | Variability of 6-mercaptopurine pharmacokinetics during oral maintenance therapy of children with acute leukemia. ( Ahström, L; Björk, O; Hayder, S; Lafolie, P; Peterson, C, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lafolie, P | 1 |
| Björk, O | 1 |
| Hayder, S | 1 |
| Ahström, L | 1 |
| Peterson, C | 1 |
1 other study available for debrisoquin and Precursor Cell Lymphoblastic Leukemia-Lymphoma
| Article | Year |
|---|---|
Variability of 6-mercaptopurine pharmacokinetics during oral maintenance therapy of children with acute leukemia.
Topics: Administration, Oral; Adolescent; Child; Child, Preschool; Debrisoquin; Erythrocytes; Fasting; Femal | 1989 |