debrisoquin has been researched along with Peripheral Nervous System Diseases in 3 studies
Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
Peripheral Nervous System Diseases: Diseases of the peripheral nerves external to the brain and spinal cord, which includes diseases of the nerve roots, ganglia, plexi, autonomic nerves, sensory nerves, and motor nerves.
| Excerpt | Relevance | Reference |
|---|
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shah, RR | 2 |
| Oates, NS | 2 |
| Idle, JR | 2 |
| Smith, RL | 2 |
| Lockhart, JD | 2 |
| Harland, CC | 1 |
| Steventon, GB | 1 |
| Marsden, JR | 1 |
3 other studies available for debrisoquin and Peripheral Nervous System Diseases
| Article | Year |
|---|---|
Impaired oxidation of debrisoquine in patients with perhexiline neuropathy.
Topics: Adult; Aged; Alcohol Drinking; Angina Pectoris; Debrisoquin; Female; Humans; Isoquinolines; Liver Fu | 1982 |
Prediction of subclinical perhexiline neuropathy in a patient with inborn error of debrisoquine hydroxylation.
Topics: Angina Pectoris; Debrisoquin; Electromyography; Humans; Hydroxylation; Isoquinolines; Male; Middle A | 1983 |
Thalidomide-induced neuropathy and genetic differences in drug metabolism.
Topics: Acetylation; Adrenergic Agents; Adult; Anti-Infective Agents; Debrisoquin; Dermatologic Agents; Fema | 1995 |