debrisoquin has been researched along with Obstructive Lung Diseases in 3 studies
Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Debrisoquine phenotyping has potential for identifying carcinogen-exposed workers at high risk of lung cancer." | 1.28 | Lung cancer risk, occupational exposure, and the debrisoquine metabolic phenotype. ( Ayesh, R; Caporaso, N; Dosemeci, M; Hayes, RB; Hetzel, M; Hoover, R; Idle, J, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sugimura, H | 1 |
| Caporaso, NE | 2 |
| Shaw, GL | 1 |
| Modali, RV | 1 |
| Gonzalez, FJ | 1 |
| Hoover, RN | 2 |
| Resau, JH | 1 |
| Trump, BF | 1 |
| Weston, A | 1 |
| Harris, CC | 1 |
| Tucker, MA | 1 |
| Hayes, RB | 2 |
| Pickle, LW | 1 |
| Issaq, HJ | 1 |
| Muschik, GM | 1 |
| Green-Gallo, L | 1 |
| Buivys, D | 1 |
| Aisner, S | 1 |
| Caporaso, N | 1 |
| Dosemeci, M | 1 |
| Hoover, R | 1 |
| Ayesh, R | 1 |
| Hetzel, M | 1 |
| Idle, J | 1 |
3 other studies available for debrisoquin and Obstructive Lung Diseases
| Article | Year |
|---|---|
Human debrisoquine hydroxylase gene polymorphisms in cancer patients and controls.
Topics: Adenocarcinoma; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cytochrome P-450 CYP2D6; Cytochrome | 1990 |
Lung cancer and the debrisoquine metabolic phenotype.
Topics: Adenocarcinoma; Case-Control Studies; Debrisoquin; Female; Humans; Isoquinolines; Lung Diseases, Obs | 1990 |
Lung cancer risk, occupational exposure, and the debrisoquine metabolic phenotype.
Topics: Asbestos; Debrisoquin; Female; Humans; Isoquinolines; Lung Diseases, Obstructive; Lung Neoplasms; Ma | 1989 |