debrisoquin has been researched along with Nervous System Disorders in 2 studies
Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dick, B | 1 |
| Küpfer, A | 1 |
| Molnàr, J | 1 |
| Braunschweig, S | 1 |
| Preisig, R | 1 |
| Burnstock, G | 1 |
1 review available for debrisoquin and Nervous System Disorders
| Article | Year |
|---|---|
Morphological changes produced by drugs acting on the autonomic nervous system.
Topics: 5,6-Dihydroxytryptamine; 5,7-Dihydroxytryptamine; Animals; Antihypertensive Agents; Autonomic Nervou | 1979 |
1 other study available for debrisoquin and Nervous System Disorders
| Article | Year |
|---|---|
[Drug hydroxylation disorders (debrisoquin type) in a random sample of the Swiss population].
Topics: Adolescent; Adult; Aged; Debrisoquin; Female; Homozygote; Humans; Hydroxylation; Isoquinolines; Male | 1982 |