debrisoquin has been researched along with Nerve Degeneration in 3 studies
Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Saner, A | 1 |
| Lorez, HP | 3 |
| Kettler, R | 3 |
| Gerold, M | 1 |
| Haeusler, G | 2 |
| Bartholini, G | 1 |
| Tranzer, JP | 1 |
3 other studies available for debrisoquin and Nerve Degeneration
| Article | Year |
|---|---|
The cardiovascular effects of the antihypertensive drug debrisoquin: A contribution to the pharmacology of chronic treatment. III. Absence of adrenergic degeneration after 8-week administration to dogs.
Topics: Adrenal Glands; Adrenergic Fibers; Animals; Cardiovascular System; Debrisoquin; Dogs; Dopamine beta- | 1978 |
Absence of degeneration of adrenergic neurones after prolonged treatment of newborn rats with debrisoquin.
Topics: Animals; Animals, Newborn; Axons; Body Weight; Catecholamines; Debrisoquin; Depression, Chemical; Do | 1975 |
Absence of degeneration of adrenergic neurons after prolonged treatment with debrisoquin.
Topics: Animals; Antihypertensive Agents; Body Weight; Debrisoquin; Dopamine beta-Hydroxylase; Ganglia; Gang | 1974 |