debrisoquin has been researched along with Muscle Contraction in 2 studies
Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pre-treatment with debrisoquine (0." | 1.26 | The sympathomimetic activity of fenfluramine hydrochloride on rat vas deferens. ( Mottram, DR; Wadhwani, D, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mottram, DR | 1 |
| Wadhwani, D | 1 |
| Giwa, SO | 1 |
| Olatunde, IA | 1 |
2 other studies available for debrisoquin and Muscle Contraction
| Article | Year |
|---|---|
The sympathomimetic activity of fenfluramine hydrochloride on rat vas deferens.
Topics: Animals; Debrisoquin; Desipramine; Drug Interactions; Fenfluramine; In Vitro Techniques; Male; Muscl | 1977 |
Proceedings: Effects of debrisoquine and propranolol on nerve-mediated and noradrenaline-induced contractions of the isolated rat hypogastric nerve-vas deferens preparation.
Topics: Animals; Debrisoquin; Drug Synergism; Hypogastric Plexus; In Vitro Techniques; Isoquinolines; Male; | 1975 |