debrisoquin has been researched along with Metabolic Acidosis in 2 studies
Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Oates, NS | 1 |
| Shah, RR | 1 |
| Idle, JR | 1 |
| Smith, RL | 1 |
| Wiholm, BE | 1 |
| Alvan, G | 1 |
| Bertilsson, L | 1 |
| Sawe, J | 1 |
| Sjöqvist, F | 1 |
2 other studies available for debrisoquin and Metabolic Acidosis
| Article | Year |
|---|---|
Phenformin-induced lacticacidosis associated with impaired debrisoquine hydroxylation.
Topics: Acidosis; Aged; Debrisoquin; Female; Humans; Isoquinolines; Lactates; Middle Aged; Phenformin; Pheno | 1981 |
Hydroxylation of debrisoquine in patients with lacticacidosis after phenformin.
Topics: Acidosis; Debrisoquin; Humans; Hydroxylation; Isoquinolines; Phenformin | 1981 |