debrisoquin has been researched along with Liver Diseases, Alcoholic in 1 studies
Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
Liver Diseases, Alcoholic: Liver diseases associated with ALCOHOLISM. It usually refers to the coexistence of two or more subentities, i.e., ALCOHOLIC FATTY LIVER; ALCOHOLIC HEPATITIS; and ALCOHOLIC CIRRHOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A comparison between the single and the "cocktail" dosage did not reveal any significant differences in the pharmacokinetic parameters." | 1.28 | [Simultaneous administration of various model substances for characterizing in vivo biotransformation in chronic liver diseases]. ( Henschel, L; Hoffmann, A; Huster, A; Jorke, D; Kraul, H; Reinhardt, M; Töpfer, R; Truckenbrodt, J, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Truckenbrodt, J | 1 |
| Kraul, H | 1 |
| Huster, A | 1 |
| Töpfer, R | 1 |
| Henschel, L | 1 |
| Hoffmann, A | 1 |
| Reinhardt, M | 1 |
| Jorke, D | 1 |
1 other study available for debrisoquin and Liver Diseases, Alcoholic
| Article | Year |
|---|---|
[Simultaneous administration of various model substances for characterizing in vivo biotransformation in chronic liver diseases].
Topics: Biotransformation; Caffeine; Debrisoquin; Dipyrone; Fatty Liver, Alcoholic; Female; Hepatitis, Chron | 1990 |