debrisoquin has been researched along with Hypertension, Renal in 3 studies
Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
Hypertension, Renal: Persistent high BLOOD PRESSURE due to KIDNEY DISEASES, such as those involving the renal parenchyma, the renal vasculature, or tumors that secrete RENIN.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A possible modulating influence of noradrenergic activity on serum lipoproteins was assessed under placebo conditions and following 4 weeks of sympathetic neurone blockade with debrisoquine in 9 normal subjects, 11 patients with mild essential hypertension, 9 normotensive, and 9 hypertensive hemodialysis patients." | 5.06 | Association between sympathetic activity and the atherogenic serum cholesterol fraction. ( Beretta-Piccoli, C; Ferrari, P; Jahn, HA; Riesen, W; Schohn, DC; Shaw, SG; Weidmann, P, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weidmann, P | 1 |
| Schohn, DC | 1 |
| Riesen, W | 1 |
| Jahn, HA | 1 |
| Ferrari, P | 1 |
| Shaw, SG | 1 |
| Beretta-Piccoli, C | 1 |
| Bückert, A | 1 |
| Schweda, E | 1 |
| Vich, V | 1 |
| Garrick, R | 1 |
| Ewan, CE | 1 |
| Bauer, GE | 1 |
| Neale, FC | 1 |
1 trial available for debrisoquin and Hypertension, Renal
| Article | Year |
|---|---|
Association between sympathetic activity and the atherogenic serum cholesterol fraction.
Topics: Adult; Arteriosclerosis; Blood Pressure; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholestero | 1990 |
2 other studies available for debrisoquin and Hypertension, Renal
| Article | Year |
|---|---|
[Therapeutic results with the hypotensive agent Declinax (debrisoquin) in mild and medium forms of hypertension].
Topics: Antihypertensive Agents; Blood Pressure; Chronic Disease; Debrisoquin; Diuretics; Drug Therapy, Comb | 1973 |
Serum uric acid in normal and hypertensive Australian subjects.
Topics: Adolescent; Adult; Age Factors; Australia; Child; Colorimetry; Debrisoquin; Female; Guanethidine; Hu | 1972 |