debrisoquin has been researched along with Hypertension, Malignant in 2 studies
Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
Hypertension, Malignant: A condition of markedly elevated BLOOD PRESSURE with DIASTOLIC PRESSURE usually greater than 120 mm Hg. Malignant hypertension is characterized by widespread vascular damage, PAPILLEDEMA, retinopathy, HYPERTENSIVE ENCEPHALOPATHY, and renal dysfunction.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamilton, M | 1 |
| Muldowney, FP | 1 |
2 other studies available for debrisoquin and Hypertension, Malignant
| Article | Year |
|---|---|
Hypertension.
Topics: Adrenergic beta-Antagonists; Aortic Diseases; Benzothiadiazines; Brain Diseases; Cerebrovascular Dis | 1974 |
Management of severe hypertension.
Topics: Chlorthalidone; Coma; Debrisoquin; Diazoxide; Guanethidine; Humans; Hypertension, Malignant; Methyld | 1972 |