debrisoquin has been researched along with Diseases, Metabolic in 3 studies
Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bertilsson, L | 1 |
| Dahl, ML | 1 |
| Sjöqvist, F | 1 |
| Aberg-Wistedt, A | 1 |
| Humble, M | 1 |
| Johansson, I | 1 |
| Lundqvist, E | 1 |
| Ingelman-Sundberg, M | 1 |
| Agúndez, JA | 1 |
| Benítez, J | 1 |
| Garrick, R | 1 |
| Ewan, CE | 1 |
| Bauer, GE | 1 |
| Neale, FC | 1 |
3 other studies available for debrisoquin and Diseases, Metabolic
| Article | Year |
|---|---|
Molecular basis for rational megaprescribing in ultrarapid hydroxylators of debrisoquine.
Topics: Debrisoquin; Female; Humans; Hydroxylation; Metabolic Diseases; Neurotic Disorders; Polymorphism, Re | 1993 |
Debrisoquine polymorphism: mechanism for very rapid oxidative phenotype.
Topics: Debrisoquin; Europe; Humans; Hydroxylation; Metabolic Diseases; Mixed Function Oxygenases; Phenotype | 1993 |
Serum uric acid in normal and hypertensive Australian subjects.
Topics: Adolescent; Adult; Age Factors; Australia; Child; Colorimetry; Debrisoquin; Female; Guanethidine; Hu | 1972 |