debrisoquin has been researched along with Disease in 2 studies
Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
Disease: A definite pathologic process with a characteristic set of signs and symptoms. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wood, M | 1 |
| Clark, DW | 1 |
1 review available for debrisoquin and Disease
| Article | Year |
|---|---|
Genetically determined variability in acetylation and oxidation. Therapeutic implications.
Topics: Acetylation; Anticonvulsants; Antidepressive Agents, Tricyclic; Debrisoquin; Disease; Drug Interacti | 1985 |
1 other study available for debrisoquin and Disease
| Article | Year |
|---|---|
Variability of human drug response.
Topics: Acetylation; Alfentanil; Anesthetics; Debrisoquin; Disease; Humans; Hydrolysis; Individuality; Isoen | 1989 |