debrisoquin has been researched along with Diabetes Mellitus, Type 2 in 3 studies
Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lautenschlager, MT | 1 |
| Viktor, S | 1 |
| Müller, UA | 1 |
| Hoffmann, A | 1 |
| Gawrońska-Szklarz, B | 1 |
| Górnik, W | 1 |
| Pawlik, A | 1 |
| Kunicki, P | 1 |
| Wójcicki, J | 1 |
| Sitkiewicz, D | 1 |
| Sych, Z | 1 |
| Kallio, J | 1 |
| Huupponen, R | 1 |
| Viikari, J | 1 |
1 trial available for debrisoquin and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
[Comparison of serum concentrations of caffeine, 4-methylaminoantipyrine, sulfamethazine and debrisoquin following oral administration of these substances as a cocktail in type II diabetics before and after insulin therapy].
Topics: Adult; Aged; Anti-Infective Agents; Caffeine; Central Nervous System Stimulants; Cytochrome P-450 En | 1996 |
2 other studies available for debrisoquin and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
N-acetylation and hydroxylation polymorphisms in type II diabetics with microvascular disturbances.
Topics: Acetylation; Adult; Aged; Debrisoquin; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Gen | 1997 |
Debrisoquine hydroxylation polymorphism in diabetic patients.
Topics: Adult; Blood Glucose; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Debrisoquin; Diabetes Mellitu | 1990 |