debrisoquin has been researched along with Dementia in 1 studies
Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hubble, JP | 1 |
| Kurth, JH | 1 |
| Glatt, SL | 1 |
| Kurth, MC | 1 |
| Schellenberg, GD | 1 |
| Hassanein, RE | 1 |
| Lieberman, A | 1 |
| Koller, WC | 1 |
1 other study available for debrisoquin and Dementia
| Article | Year |
|---|---|
Gene-toxin interaction as a putative risk factor for Parkinson's disease with dementia.
Topics: Aged; Apolipoproteins; Case-Control Studies; Comorbidity; Debrisoquin; Dementia; Environmental Expos | 1998 |