Compounds > debrisoquin
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debrisoquin and Constitutional Liver Dysfunction

debrisoquin has been researched along with Constitutional Liver Dysfunction in 2 studies

Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fengler, JD2
Baumgarten, R1
Eike, E2
Eike, O2
Siegmund, W2
Franke, G2
Zschiesche, M2
Meisel, P1
Wulkow, R1

Other Studies

2 other studies available for debrisoquin and Constitutional Liver Dysfunction

ArticleYear
[Genetic polymorphism in Gilbert-Meulengracht syndrome (GMS)].
    Zeitschrift fur Gastroenterologie, 1993, Volume: 31 Suppl 2

    Topics: Acetylation; Arylamine N-Acetyltransferase; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System;

1993
N-acetylation and debrisoquine hydroxylation polymorphisms in patients with Gilbert's syndrome.
    British journal of clinical pharmacology, 1991, Volume: 32, Issue:4

    Topics: Acetylation; Adolescent; Adult; Aged; Debrisoquin; Female; Gilbert Disease; Humans; Hydroxylation; M

1991