debrisoquin has been researched along with Congenital Adrenal Hyperplasia in 1 studies
Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Antipyrine salivary clearance and half-life and the rate of formation of three principal metabolites of antipyrine (4-hydroxyantipyrine, 3-hydroxymethylantipyrine and norantipyrine) were assessed in nine children with congenital adrenal hyperplasia, six of whom were salt-losers and three of whom were non-salt-losers." | 7.67 | Antipyrine clearance and metabolite formation in children with congenital adrenal hyperplasia. ( Breimer, DD; Bruining, GJ; De Jongh, BM; Tenkate-Westerhof, EW; Teunissen, MW, 1985) |
| "Antipyrine salivary clearance and half-life and the rate of formation of three principal metabolites of antipyrine (4-hydroxyantipyrine, 3-hydroxymethylantipyrine and norantipyrine) were assessed in nine children with congenital adrenal hyperplasia, six of whom were salt-losers and three of whom were non-salt-losers." | 3.67 | Antipyrine clearance and metabolite formation in children with congenital adrenal hyperplasia. ( Breimer, DD; Bruining, GJ; De Jongh, BM; Tenkate-Westerhof, EW; Teunissen, MW, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Teunissen, MW | 1 |
| Bruining, GJ | 1 |
| De Jongh, BM | 1 |
| Tenkate-Westerhof, EW | 1 |
| Breimer, DD | 1 |
1 other study available for debrisoquin and Congenital Adrenal Hyperplasia
| Article | Year |
|---|---|
Antipyrine clearance and metabolite formation in children with congenital adrenal hyperplasia.
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Antipyrine; Biotransformation; Child; Cytochrome P-450 | 1985 |