debrisoquin has been researched along with Chromosome Deletion in 1 studies
Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
Chromosome Deletion: Actual loss of portion of a chromosome.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gaedigk, A | 1 |
| Blum, M | 1 |
| Gaedigk, R | 1 |
| Eichelbaum, M | 1 |
| Meyer, UA | 1 |
1 other study available for debrisoquin and Chromosome Deletion
| Article | Year |
|---|---|
Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism.
Topics: Base Sequence; Chromosome Deletion; Chromosomes, Human, Pair 22; Cytochrome P-450 Enzyme System; Deb | 1991 |