debrisoquin has been researched along with Carcinoma, Small Cell in 4 studies
Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
Carcinoma, Small Cell: An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shaw, GL | 2 |
| Weiffenbach, B | 1 |
| Falk, RT | 1 |
| Frame, JN | 1 |
| Issaq, HJ | 1 |
| Moir, DT | 1 |
| Caporaso, N | 1 |
| Sugimura, H | 1 |
| Caporaso, NE | 1 |
| Modali, RV | 1 |
| Gonzalez, FJ | 1 |
| Hoover, RN | 1 |
| Resau, JH | 1 |
| Trump, BF | 1 |
| Weston, A | 1 |
| Harris, CC | 1 |
| Speirs, CJ | 1 |
| Murray, S | 1 |
| Davies, DS | 1 |
| Biola Mabadeje, AF | 1 |
| Boobis, AR | 1 |
| Roots, I | 1 |
| Drakoulis, N | 1 |
| Ploch, M | 1 |
| Heinemeyer, G | 1 |
| Loddenkemper, R | 1 |
| Minks, T | 1 |
| Nitz, M | 1 |
| Otte, F | 1 |
| Koch, M | 1 |
4 other studies available for debrisoquin and Carcinoma, Small Cell
| Article | Year |
|---|---|
Frequency of the variant allele CYP2D6(C) among North American Caucasian lung cancer patients and controls.
Topics: Alleles; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Case-Control Studies; Cytochrome P-450 CYP | 1997 |
Human debrisoquine hydroxylase gene polymorphisms in cancer patients and controls.
Topics: Adenocarcinoma; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cytochrome P-450 CYP2D6; Cytochrome | 1990 |
Debrisoquine oxidation phenotype and susceptibility to lung cancer.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Debrisoqui | 1990 |
Debrisoquine hydroxylation phenotype, acetylation phenotype, and ABO blood groups as genetic host factors of lung cancer risk.
Topics: ABO Blood-Group System; Acetylation; Acetyltransferases; Arylamine N-Acetyltransferase; Caffeine; Ca | 1988 |