debrisoquin has been researched along with Breast Diseases in 1 studies
Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
Breast Diseases: Pathological processes of the BREAST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "129 female patients with breast cancer and 79 controls undergoing biopsy for benign breast conditions had debrisoquine hydroxylator phenotype established." | 3.68 | Cytochrome P450dbl phenotypes in malignant and benign breast disease. ( Fentiman, IS; Hamed, H; Idle, JR; Pontin, JE, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pontin, JE | 1 |
| Hamed, H | 1 |
| Fentiman, IS | 1 |
| Idle, JR | 1 |
1 other study available for debrisoquin and Breast Diseases
| Article | Year |
|---|---|
Cytochrome P450dbl phenotypes in malignant and benign breast disease.
Topics: Adult; Breast Diseases; Breast Neoplasms; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; D | 1990 |