debrisoquin has been researched along with Anesthesia in 2 studies
Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
Anesthesia: A state characterized by loss of feeling or sensation. This depression of nerve function is usually the result of pharmacologic action and is induced to allow performance of surgery or other painful procedures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Debrisoquin was administered twice daily at the dose of 2." | 1.26 | The cardiovascular effects of the antihypertensive drug debrisoquin: A contribution to the pharmacology of chronic treatment. II. Eight-week administration to dogs. ( Cavero, I; Gerold, M; Haeusler, G; Saner, A, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gerold, M | 1 |
| Cavero, I | 1 |
| Saner, A | 1 |
| Haeusler, G | 1 |
| Antonaccio, MJ | 1 |
2 other studies available for debrisoquin and Anesthesia
| Article | Year |
|---|---|
The cardiovascular effects of the antihypertensive drug debrisoquin: A contribution to the pharmacology of chronic treatment. II. Eight-week administration to dogs.
Topics: Anesthesia; Animals; Blood Pressure; Body Weight; Cardiovascular System; Debrisoquin; Dogs; Drug Tol | 1978 |
Paradoxical vagal tachycardia in ganglion-blocked anesthetized dogs.
Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Atropine; Blood Pressure; Bretylium Compounds; Chl | 1974 |