debrisoquin has been researched along with Allergy, Drug in 2 studies
Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, BK | 1 |
| Vesell, ES | 1 |
2 other studies available for debrisoquin and Allergy, Drug
| Article | Year |
|---|---|
Metabolic basis of adverse drug reactions.
Topics: Acetaminophen; Acetylation; Adrenergic beta-Antagonists; Adult; Age Factors; Child; Debrisoquin; Dru | 1986 |
Pharmacogenetic approaches to the prediction of drug response.
Topics: Debrisoquin; Disease Susceptibility; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Re | 1986 |