debrisoquin has been researched along with Alcohol Abuse in 2 studies
Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Debruyne, D | 1 |
| Gram, LF | 1 |
| Grollier, G | 1 |
| Camsonne, R | 1 |
| Agron, L | 1 |
| Dao, MT | 1 |
| Lacotte, J | 1 |
| Bigot, MC | 1 |
| Moulin, M | 1 |
| Kalow, W | 1 |
1 review available for debrisoquin and Alcohol Abuse
| Article | Year |
|---|---|
Genetics of drug transformation.
Topics: Alcoholism; Biotransformation; Cytochromes; Debrisoquin; Ethanol; Genes, Recessive; Genetics; Humans | 1986 |
1 other study available for debrisoquin and Alcohol Abuse
| Article | Year |
|---|---|
Quinidine disposition in relation to antipyrine elimination and debrisoquine phenotype in alcoholic patients with and without cirrhosis.
Topics: Adult; Aged; Alcoholism; Antipyrine; Chromatography, Liquid; Debrisoquin; Female; Half-Life; Humans; | 1989 |