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debrisoquin and Adverse Drug Event

debrisoquin has been researched along with Adverse Drug Event in 7 studies

Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.

Research

Studies (7)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (85.71)	18.7374
1990's	1 (14.29)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Paxton, JW	1
Roots, I	1
Gross, AS	1
Kroemer, HK	1
Eichelbaum, M	1
Park, BK	1
Vesell, ES	1
Evans, DA	1

Reviews

2 reviews available for debrisoquin and Adverse Drug Event

Article	Year
Genetic polymorphism of drug metabolism in humans. Advances in experimental medicine and biology, 1991, Volume: 283 Topics: Acetylation; Debrisoquin; Drug-Related Side Effects and Adverse Reactions; Humans; Mephenytoin; Phar	1991
Ethnic differences in reactions to drugs and xenobiotics. Therapy. Progress in clinical and biological research, 1986, Volume: 214 Topics: Acetylation; Debrisoquin; Drug Interactions; Drug Therapy; Drug-Related Side Effects and Adverse Rea	1986

Other Studies

5 other studies available for debrisoquin and Adverse Drug Event

Article	Year
Pharmacogenetic polymorphism of drug metabolism. The New Zealand medical journal, 1984, Aug-22, Volume: 97, Issue:762 Topics: Acetylation; Acetyltransferases; Debrisoquin; Drug Interactions; Drug-Related Side Effects and Adver	1984
Protecting the poor metaboliser--from what? British journal of clinical pharmacology, 1984, Volume: 17, Issue:4 Topics: Debrisoquin; Drug-Related Side Effects and Adverse Reactions; Humans; Hydroxylation; Metoprolol; Pha	1984
[Genetic causes for the variability of effects and side effects of drugs]. Der Internist, 1982, Volume: 23, Issue:11 Topics: Debrisoquin; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hydroxylation; Kinetic	1982
Metabolic basis of adverse drug reactions. Journal of the Royal College of Physicians of London, 1986, Volume: 20, Issue:3 Topics: Acetaminophen; Acetylation; Adrenergic beta-Antagonists; Adult; Age Factors; Child; Debrisoquin; Dru	1986
Pharmacogenetic approaches to the prediction of drug response. NIDA research monograph, 1986, Volume: 66 Topics: Debrisoquin; Disease Susceptibility; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Re	1986