debrisoquin has been researched along with Acute Lymphoid Leukemia in 1 studies
Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Food intake reduced the time to peak concentration both in plasma, from 1." | 1.28 | Variability of 6-mercaptopurine pharmacokinetics during oral maintenance therapy of children with acute leukemia. ( Ahström, L; Björk, O; Hayder, S; Lafolie, P; Peterson, C, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lafolie, P | 1 |
| Björk, O | 1 |
| Hayder, S | 1 |
| Ahström, L | 1 |
| Peterson, C | 1 |
1 other study available for debrisoquin and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
Variability of 6-mercaptopurine pharmacokinetics during oral maintenance therapy of children with acute leukemia.
Topics: Administration, Oral; Adolescent; Child; Child, Preschool; Debrisoquin; Erythrocytes; Fasting; Femal | 1989 |