debrisoquin has been researched along with Acute Hepatic Failure in 2 studies
Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, RR | 1 |
| Zheng, YW | 1 |
| Li, B | 1 |
| Tsuchida, T | 1 |
| Ueno, Y | 1 |
| Nie, YZ | 1 |
| Taniguchi, H | 1 |
| Gustafsson, LL | 1 |
| Eriksson, LS | 1 |
| Dahl, ML | 1 |
| Eleborg, L | 1 |
| Ericzon, BG | 1 |
| Nyberg, A | 1 |
2 other studies available for debrisoquin and Acute Hepatic Failure
| Article | Year |
|---|---|
Human hepatic stem cells transplanted into a fulminant hepatic failure Alb-TRECK/SCID mouse model exhibit liver reconstitution and drug metabolism capabilities.
Topics: Animals; Cell Differentiation; Cell Proliferation; Cells, Cultured; Chimera; Debrisoquin; Diphtheria | 2015 |
Cyclophosphamide-induced acute liver failure requiring transplantation in a patient with genetically deficient debrisoquine metabolism: a causal relationship?
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cyclophosphamide; Cytochrome P-450 CYP2D6; Debrisoquin; | 1996 |