debrisoquin has been researched along with Acute Brain Injuries in 2 studies
Debrisoquin: An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gerstenbrand, F | 1 |
| Hackl, JM | 2 |
| Rumpl, E | 2 |
| Hörtnagl, H | 2 |
| Hammerle, AF | 1 |
| Brücke, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Controlling Hyperadrenergic Activity in Neurologic Injury[NCT01343329] | Phase 1/Phase 2 | 0 participants (Actual) | Interventional | 2011-07-31 | Withdrawn (stopped due to Unable to enroll subjects that fit study criteria.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for debrisoquin and Acute Brain Injuries
| Article | Year |
|---|---|
[Use of a beta blocker in a traumatic apallic syndrome].
Topics: Adrenergic beta-Antagonists; Adult; Blood Glucose; Brain Injuries; Brain Stem; Coma; Debrisoquin; Dr | 1981 |
The activity of the sympathetic nervous system following severe head injury.
Topics: Adolescent; Adult; Brain Injuries; Debrisoquin; Electrocardiography; Epinephrine; Female; Heart Rate | 1980 |