deamino-arginine-vasopressin and Pre-Eclampsia

Transient diabetes insipidus (DI) is a disease of late pregnancy, that has been reported with increasing frequency. Although initially thought to be nephrogenic, the etiology of this syndrome is most likely excess vasopressinase activity. The disease is associated with preeclampsia with liver involvement. Infants of mothers with the syndrome are predominantly male. Management may be with deamino D arginine vasopressin (dDAVP) during gestation and postpartum since vasopressinase does not break down dDAVP. The copious urine output may disguise preeclampsia. Fluid restriction should be avoided as it will lead to dehydration and hemoconcentration.

Topics: Adult; Cystinyl Aminopeptidase; Deamino Arginine Vasopressin; Diabetes Insipidus; Female; Humans; Hypertension; Infant, Newborn; Liver; Polyuria; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Syndrome

Topics: Adult; Antidiuretic Agents; Comorbidity; Deamino Arginine Vasopressin; Diabetes Insipidus; Female; Humans; Pre-Eclampsia; Pregnancy; Pregnancy in Diabetics; Pregnancy Trimester, Second

Up to 1984, 69 cases of diabetes insipidus associated with pregnancy had been reported on. In only four such cases did preeclampsia develop. We treated a patient for the fifth such case.

Topics: Adult; Cesarean Section; Deamino Arginine Vasopressin; Diabetes Insipidus; Female; Humans; Infant, Newborn; Magnesium Sulfate; Male; Pre-Eclampsia; Pregnancy; Pregnancy in Diabetics

Topics: Arginine Vasopressin; Deamino Arginine Vasopressin; Female; Humans; Pre-Eclampsia; Pregnancy; Vasopressins

Topics: Arginine Vasopressin; Deamino Arginine Vasopressin; Female; Pre-Eclampsia; Pregnancy; Research; Vasopressins