Page last updated: 2024-10-26

ddt and Parkinson Disease

ddt has been researched along with Parkinson Disease in 5 studies

1,1-bis(p-chlorophenyl)-2,2,2-trichloroethane: structure in first source

Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Research Excerpts

ExcerptRelevanceReference
"Dieldrin was detected in 6 of 20 PD brains, 1 of 7 AD, and in none of 14 control samples."1.29Parkinson's disease and brain levels of organochlorine pesticides. ( Bean, J; Briggle, T; Fleming, L; Mann, JB; Sanchez-Ramos, JR, 1994)
"Dieldrin (HEOD) was significantly decreased in PD brain when analysed by lipid weight."1.29Organochlorine compounds in human brain. ( Corrigan, FM; French, M; Murray, L, 1996)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Huang, M1
Bargues-Carot, A1
Riaz, Z1
Wickham, H1
Zenitsky, G1
Jin, H1
Anantharam, V1
Kanthasamy, A1
Kanthasamy, AG1
Rossi, M1
Scarselli, M1
Fasciani, I1
Maggio, R1
Giorgi, F1
Fleming, L1
Mann, JB1
Bean, J1
Briggle, T1
Sanchez-Ramos, JR1
Corrigan, FM1
French, M1
Murray, L1
Yang, MC1
McLean, AJ1
Rivory, LP1
Le Couteur, DG1

Reviews

2 reviews available for ddt and Parkinson Disease

ArticleYear
Impact of Environmental Risk Factors on Mitochondrial Dysfunction, Neuroinflammation, Protein Misfolding, and Oxidative Stress in the Etiopathogenesis of Parkinson's Disease.
    International journal of molecular sciences, 2022, Sep-16, Volume: 23, Issue:18

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; alpha-Synuclein; Animals; DDT; Dieldrin; Herbicides; H

2022
Dichlorodiphenyltrichloroethane (DDT) induced extracellular vesicle formation: a potential role in organochlorine increased risk of Parkinson's disease.
    Acta neurobiologiae experimentalis, 2017, Volume: 77, Issue:2

    Topics: Animals; DDT; Extracellular Vesicles; Humans; Hydrocarbons, Chlorinated; Parkinson Disease; Pesticid

2017

Other Studies

3 other studies available for ddt and Parkinson Disease

ArticleYear
Parkinson's disease and brain levels of organochlorine pesticides.
    Annals of neurology, 1994, Volume: 36, Issue:1

    Topics: Age Factors; Aged; Alzheimer Disease; Brain Chemistry; Cross-Sectional Studies; DDT; Dieldrin; Femal

1994
Organochlorine compounds in human brain.
    Human & experimental toxicology, 1996, Volume: 15, Issue:3

    Topics: Aged; Aged, 80 and over; Brain Chemistry; Cerebral Cortex; DDT; Dieldrin; Female; Humans; Male; Park

1996
Hepatic disposition of neurotoxins and pesticides.
    Pharmacology & toxicology, 2000, Volume: 87, Issue:6

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Biological Transport; DDT; Hepatocytes; Human

2000