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ddt and Liver Neoplasms

ddt has been researched along with Liver Neoplasms in 54 studies

1,1-bis(p-chlorophenyl)-2,2,2-trichloroethane: structure in first source

Liver Neoplasms: Tumors or cancer of the LIVER.

Research Excerpts

ExcerptRelevanceReference
"Dichlorodiphenyltrichloroethane (p,p'-DDT), an organochlorine pesticide known to have deleterious health effects in humans, has been linked to hepatocellular carcinoma (HCC) in rodents."3.78Dichlorodiphenyltrichloroethane and risk of hepatocellular carcinoma. ( Chen, G; Evans, AA; Graubard, BI; LeBlanc, A; Lin, W; London, WT; McGlynn, KA; Persson, EC; Weber, JP, 2012)
"Eligibility criteria included examining hepatocellular carcinoma (HCC) or primary liver cancer, pesticides as an exposure of interest, and individual-level incidence."2.55Pesticide exposure and liver cancer: a review. ( Bertrand, KA; Brooks, MM; Chang, CH; Hart, JE; Laden, F; Ruddell, D; Talbott, EO; VoPham, T; Weissfeld, JL; Yuan, JM, 2017)
"A calculation of crude liver cancer risk found that there would be 26 liver cancers per 100 000 persons per year in the lowest quintile of DDT exposure versus 46 liver cancers per 100 000 persons per year in the highest quintile of DDT exposure."1.33Serum concentrations of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) and 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE) and risk of primary liver cancer. ( Abnet, CC; Dawsey, SM; Fan, JH; Katki, H; Mark, SD; McGlynn, KA; O'Brien, TR; Ortiz-Conde, BA; Qiao, YL; Sun, XD; Taylor, PR; Weber, JP; Wei, WQ; Zhang, M, 2006)
"Choline was not effective in inhibiting the development of lung metastases in either case."1.27Effect of methionine and choline on liver tumor promotion by phenobarbital and DDT in diethylnitrosamine-initiated rats. ( Hoover, KL; Poirier, LA; Shivapurkar, N, 1986)
"DDT is a pesticide used in malaria-control programmes throughout the world."1.26Effects of long-term intake of DDT on rats. ( Bronczyk, SA; Cabral, JR; Hall, RK; Rossi, L; Shubik, P, 1982)
"Hepatomas were found to be predominant neoplasm, observed at a frequency that decreased from 5."1.26Hepatomas and other neoplasms in the atlantic hagfish (Myxine glutinosa): a histopathologic and chemical study. ( Falkmer, S; Marklund, S; Mattsson, PE; Rappe, C, 1978)

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-199046 (85.19)18.7374
1990's1 (1.85)18.2507
2000's3 (5.56)29.6817
2010's4 (7.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Engel, LS1
Zabor, EC1
Satagopan, J1
Widell, A1
Rothman, N1
O'Brien, TR2
Zhang, M2
Van Den Eeden, SK1
Grimsrud, TK1
Jin, XT1
Song, L1
Zhao, JY1
Li, ZY1
Zhao, MR1
Liu, WP1
VoPham, T1
Bertrand, KA1
Hart, JE1
Laden, F1
Brooks, MM1
Yuan, JM1
Talbott, EO1
Ruddell, D1
Chang, CH1
Weissfeld, JL1
Persson, EC1
Graubard, BI1
Evans, AA1
London, WT1
Weber, JP2
LeBlanc, A1
Chen, G1
Lin, W1
McGlynn, KA2
Wu, XJ1
Lu, WQ1
Mersch-Sundermann, V1
DAWE, CJ1
STANTON, MF1
SCHWARTZ, FJ1
Medina-Díaz, IM1
Elizondo, G1
Abnet, CC1
Sun, XD1
Fan, JH1
Wei, WQ1
Ortiz-Conde, BA1
Dawsey, SM1
Taylor, PR1
Katki, H1
Mark, SD1
Qiao, YL1
Deichmann, WB5
Keplinger, M1
Sala, F1
Glass, E1
Mazue, G1
Gouy, D1
Remandet, B1
Garbay, JM1
Nigam, SK2
Bhatt, DK1
Karnik, AB2
Thakore, KN1
Aravinda Babu, K1
Lakkad, BC1
Kashyap, SK2
Chatterjee, SK2
Cabral, JR2
Hall, RK2
Rossi, L3
Bronczyk, SA2
Shubik, P4
Wahrendorf, J1
Williams, GM1
Telang, S1
Tong, C1
Huff, JE1
Hitachi, PM1
Yamada, K1
Takayama, S1
Tilak, TB1
Nagarajan, V1
Tulpule, PG1
Falkmer, S1
Marklund, S1
Mattsson, PE1
Rappe, C1
MacDonald, WE2
Syrowatka, T1
Jurek, A1
Nazarewicz, T1
Butler, WH1
Jones, G1
Deichman, WB1
Jansen, JD1
Ravera, M1
Repetti, G1
Santi, L1
Archer, VE1
Gupta, RC1
Peraino, C1
Fry, RJ1
Staffeldt, E1
Christopher, JP1
Turusov, VS4
Khar'kovskaia, NA1
Kondalenko, VF1
Poltoranina, VS1
Svinolupova, SI1
Khrustalev, SA1
Engel'gardt, NV1
Büsser, MT1
Lutz, WK1
Shivapurkar, N1
Hoover, KL1
Poirier, LA1
Gold, B1
Brunk, G1
Sugie, S1
Mori, H1
Takahashi, M1
Thorpe, E2
Walker, AI2
Keplinger, ML1
Glass, EM2
Agthe, C1
Garcia, H1
Tomatis, L5
Wenyon, E1
Khudoleĭ, VV1
Stevenson, DE1
Day, NE2
Gati, E2
Charles, RT3
Deringer, MK1
Dunn, TB1
Stewart, HL1
Turusov, V2
Day, N2
Breslow, NE1
Terracini, B1
Testa, MC1
Carbral, JR1
Boiocchi, M1
Claus, G1
Maddox, J1
Kilgore, WW1
Li, MY1
Gingell, R1
Wallcave, L1
Laws, ER1
Radomski, JL2
Clizer, EE1

Reviews

5 reviews available for ddt and Liver Neoplasms

ArticleYear
Pesticide exposure and liver cancer: a review.
    Cancer causes & control : CCC, 2017, Volume: 28, Issue:3

    Topics: Biomarkers; Carcinoma, Hepatocellular; China; DDT; Egypt; Environmental Exposure; Humans; Liver Neop

2017
Report of ICPEMC Task Group 5 on the differentiation between genotoxic and non-genotoxic carcinogens.
    Mutation research, 1984, Volume: 133, Issue:1

    Topics: Animals; Butylated Hydroxytoluene; Carcinogens; Cell Line; DDT; Dieldrin; Dioxins; Drug Evaluation,

1984
Microsomal metabolism as a determinant of aflatoxin toxicity.
    Experientia, 1975, Aug-15, Volume: 31, Issue:8

    Topics: Aflatoxins; Animals; Carcinoma, Hepatocellular; DDT; Dose-Response Relationship, Drug; Liver Neoplas

1975
[Experimental neoplasms in fish].
    Voprosy onkologii, 1971, Volume: 17, Issue:1

    Topics: Aflatoxins; Animal Feed; Animals; Benz(a)Anthracenes; Carcinogens; Carcinoma, Hepatocellular; Catara

1971
The carcinogenicity of pesticides.
    Residue reviews, 1973, Volume: 48, Issue:0

    Topics: Aldrin; Animals; Carcinogens; DDT; Dieldrin; Dose-Response Relationship, Drug; Drug Synergism; Enzym

1973

Other Studies

49 other studies available for ddt and Liver Neoplasms

ArticleYear
Prediagnostic serum organochlorine insecticide concentrations and primary liver cancer: A case-control study nested within two prospective cohorts.
    International journal of cancer, 2019, 11-01, Volume: 145, Issue:9

    Topics: Adult; Aged; Case-Control Studies; Chlordan; DDT; Female; Humans; Hydrocarbons, Chlorinated; Insecti

2019
Dichlorodiphenyltrichloroethane exposure induces the growth of hepatocellular carcinoma via Wnt/β-catenin pathway.
    Toxicology letters, 2014, Feb-10, Volume: 225, Issue:1

    Topics: Animals; Antioxidants; beta Catenin; Carcinogens; Carcinoma, Hepatocellular; Cell Proliferation; Cyc

2014
Dichlorodiphenyltrichloroethane and risk of hepatocellular carcinoma.
    International journal of cancer, 2012, Nov-01, Volume: 131, Issue:9

    Topics: Adult; Carcinoma, Hepatocellular; Case-Control Studies; Cohort Studies; DDT; Dichlorodiphenyl Dichlo

2012
Benzo(a)pyrene induced micronucleus formation was modulated by persistent organic pollutants (POPs) in metabolically competent human HepG2 cells.
    Toxicology letters, 2003, Sep-30, Volume: 144, Issue:2

    Topics: Benzo(a)pyrene; Cell Line; Chlorodiphenyl (54% Chlorine); DDT; Environmental Pollutants; Humans; Ind

2003
HEPATIC NEOPLASMS IN NATIVE BOTTOM-FEEDING FISH OF DEEP CREEK LAKE, MARYLAND.
    Cancer research, 1964, Volume: 24

    Topics: Carcinogens; DDT; Eukaryota; Fishes; Hydrocarbons; Lakes; Liver Neoplasms; Maryland; Neoplasms; Neop

1964
Transcriptional induction of CYP3A4 by o,p'-DDT in HepG2 cells.
    Toxicology letters, 2005, May-16, Volume: 157, Issue:1

    Topics: Carcinoma, Hepatocellular; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DDT; Dose-Respons

2005
Serum concentrations of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) and 1,1-dichloro-2,2-bis(p-chlorophenyl)ethylene (DDE) and risk of primary liver cancer.
    Journal of the National Cancer Institute, 2006, Jul-19, Volume: 98, Issue:14

    Topics: Adult; Aged; Carcinogens; Case-Control Studies; China; DDT; Dichlorodiphenyl Dichloroethylene; Envir

2006
Synergism among oral carcinogens. IV. The simultaneous feeding of four tumorigens to rats.
    Toxicology and applied pharmacology, 1967, Volume: 11, Issue:1

    Topics: Animals; Behavior, Animal; Body Weight; Carcinogens; DDT; Diet; Drug Synergism; Female; Growth; Kidn

1967
Limited in vivo bioassays.
    Annals of the New York Academy of Sciences, 1983, Volume: 407

    Topics: Animals; Benzodiazepines; Biological Assay; DDT; Female; gamma-Glutamyltransferase; Liver Neoplasms;

1983
Experimental studies on insecticides commonly used in India.
    Journal of cancer research and clinical oncology, 1981, Volume: 99, Issue:1-2

    Topics: Animals; Chromosomes; DDT; Female; Hexachlorocyclohexane; India; Isoenzymes; L-Lactate Dehydrogenase

1981
Effects of long-term intake of DDT on rats.
    Tumori, 1982, Feb-28, Volume: 68, Issue:1

    Topics: Animals; Carcinoma, Hepatocellular; DDT; Female; Liver Neoplasms; Male; Neoplasms, Experimental; Rat

1982
Simultaneous analysis of different tumor types in a long-term carcinogenicity study with scheduled sacrifices.
    Journal of the National Cancer Institute, 1983, Volume: 70, Issue:5

    Topics: Animals; Carcinogens; DDT; Liver Neoplasms; Lung Neoplasms; Lymphoma; Male; Mice; Models, Biological

1983
Lack of carcinogenicity of DDT in hamsters.
    Tumori, 1982, Feb-28, Volume: 68, Issue:1

    Topics: Adrenal Gland Neoplasms; Animals; Body Weight; Cricetinae; DDT; Female; Liver; Liver Neoplasms; Male

1982
Inhibition of intercellular communication between liver cells by the liver tumor promoter 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane.
    Cancer letters, 1981, Volume: 11, Issue:4

    Topics: Animals; Cell Communication; Cells, Cultured; DDT; Dose-Response Relationship, Drug; Liver; Liver Ne

1981
DDT and cancer.
    Clinical toxicology, 1980, Volume: 16, Issue:3

    Topics: Animals; Carcinogens; DDT; Liver Neoplasms; Mice; Neoplasms, Experimental

1980
Cytologic changes induced in rat livers cells by short-term exposure to chemical substances.
    Journal of the National Cancer Institute, 1975, Volume: 54, Issue:5

    Topics: 2-Acetylaminofluorene; Aflatoxins; Animals; Butanes; Carcinogens; Chromosome Aberrations; DDT; Dieth

1975
Hepatomas and other neoplasms in the atlantic hagfish (Myxine glutinosa): a histopathologic and chemical study.
    Annals of the New York Academy of Sciences, 1978, Sep-29, Volume: 298

    Topics: Adenoma, Bile Duct; Animals; Carcinogens, Environmental; Carcinoma, Hepatocellular; DDT; Fish Diseas

1978
Organochlorine pesticides and liver cancer deaths in the United States, 1930--1972.
    Ecotoxicology and environmental safety, 1977, Volume: 1, Issue:1

    Topics: Aldrin; Chemical Industry; DDT; Dieldrin; Humans; Insecticides; Liver Neoplasms; Occupational Diseas

1977
[Effect of DDT on the hepatotoxic action of 2-acetylaminofluorene in Wistar rats].
    Roczniki Panstwowego Zakladu Higieny, 1978, Volume: 29, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; DDT; Fluorenes; Liver; Liver Neoplasms; Male; Neoplasms, Experimenta

1978
Pathological and toxicological data on chlorinated pesticides and phenobarbital.
    Ecotoxicology and environmental safety, 1978, Volume: 1, Issue:4

    Topics: Animals; Body Weight; Carcinogens; DDT; Drug Interactions; Female; Insecticides; Liver Neoplasms; Ma

1978
Cummings Memorial Lecture - 1975. The market basket: food for thought.
    American Industrial Hygiene Association journal, 1975, Volume: 36, Issue:6

    Topics: Aldrin; Animals; Carcinogens; DDT; Dieldrin; Disease Models, Animal; Dose-Response Relationship, Dru

1975
Medical and toxicological research on dieldrin and related compounds.
    Environmental quality and safety, 1976, Volume: 5

    Topics: Adult; Animals; Carcinogens; DDT; Dieldrin; Dogs; Haplorhini; Humans; Liver Neoplasms; Male; Maximum

1976
Long-term administration of DDT or phenobarbital-Na in Wistar rats.
    International journal of cancer, 1977, Feb-15, Volume: 19, Issue:2

    Topics: Age Factors; Animals; Body Weight; DDT; Drug Administration Schedule; Female; Liver Neoplasms; Male;

1977
Liver cancer deaths.
    American Industrial Hygiene Association journal, 1977, Volume: 38, Issue:2

    Topics: Carcinogens; DDT; Death Certificates; Environmental Exposure; Humans; Liver Neoplasms

1977
Carcinogenicity of DDT (dichlorodiphenyl trichloroethane) in pure inbred Swiss mice.
    International journal of cancer, 1977, May-15, Volume: 19, Issue:5

    Topics: Administration, Oral; Administration, Topical; Animals; Carcinogens; DDT; Injections, Subcutaneous;

1977
Comments on alleged carcinogenicity of DDT as documented by EPA, review prepared for House Committee on Appropriation, July 1975.
    Clinical toxicology, 1976, Volume: 9, Issue:5

    Topics: Animals; Carcinogens; DDT; Dose-Response Relationship, Drug; Female; Government Agencies; Humans; Li

1976
Comparative enhancing effects of phenobarbital, amobarbital, diphenylhydantoin, and dichlorodiphenyltrichloroethane on 2-acetylaminofluorene-induced hepatic tumorigenesis in the rat.
    Cancer research, 1975, Volume: 35, Issue:10

    Topics: 2-Acetylaminofluorene; Amobarbital; Animals; DDT; DNA, Neoplasm; Drug Synergism; Liver; Liver Neopla

1975
[Mouse hepatoblastoma: comparative aspects].
    Arkhiv patologii, 1991, Volume: 53, Issue:4

    Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; DDT; Liver Neoplasms; Liver Neoplasms, Experimental

1991
Stimulation of DNA synthesis in rat and mouse liver by various tumor promoters.
    Carcinogenesis, 1987, Volume: 8, Issue:10

    Topics: Adipates; Aflatoxin B1; Aflatoxins; Aldrin; Animals; Benzidines; Biological Availability; Carbon Tet

1987
Effect of methionine and choline on liver tumor promotion by phenobarbital and DDT in diethylnitrosamine-initiated rats.
    Carcinogenesis, 1986, Volume: 7, Issue:4

    Topics: Adenocarcinoma; Animals; Choline; Cocarcinogenesis; DDT; Diethylnitrosamine; Liver Neoplasms; Lung N

1986
The effect of subchronic feeding of 1,1-dichloro-2,2-bis(4'-chlorophenyl)ethene (DDE) on its metabolism in mice.
    Carcinogenesis, 1986, Volume: 7, Issue:7

    Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; DDT; Dichlorodiphenyl Dichloroethy

1986
Effect of in vivo exposure to the liver tumor promoters phenobarbital or DDT on the gap junctions of rat hepatocytes: a quantitative freeze-fracture analysis.
    Carcinogenesis, 1987, Volume: 8, Issue:1

    Topics: Animals; DDT; Freeze Fracturing; Intercellular Junctions; Liver; Liver Neoplasms; Male; Microscopy,

1987
The toxicology of dieldrin (HEOD). II. Comparative long-term oral toxicity studies in mice with dieldrin, DDT, phenobarbitone, -BHC and -BHC.
    Food and cosmetics toxicology, 1973, Volume: 11, Issue:3

    Topics: Administration, Oral; Animals; DDT; Dieldrin; Female; Hepatomegaly; Hexachlorocyclohexane; Hyperplas

1973
[Synergism between orally active carcinogens. IV. Results of simultaneous feeding of 4 carcinogens in rats].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1967, Volume: 257, Issue:1

    Topics: Animals; Carcinogens; DDT; Drug Synergism; Liver Neoplasms; Neoplasms, Experimental; Rats; Thiourea

1967
Study of the potential carcinogenicity of DDT in the Syrian golden hamster.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1970, Volume: 134, Issue:1

    Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Adenoma; Adrenal Gland Neoplasms; Animals; Body

1970
The use of the Syrian golden hamster in chronic toxicity testing.
    Progress in experimental tumor research, 1972, Volume: 16

    Topics: Animals; Azo Compounds; Benz(a)Anthracenes; Carcinogens; Carcinoma, Hepatocellular; Carcinoma, Squam

1972
The toxicology of dieldrin (HEOD). I. Long-term oral toxicity studies in mice.
    Food and cosmetics toxicology, 1973, Volume: 11, Issue:3

    Topics: Administration, Oral; Animals; Body Weight; Carcinoma, Hepatocellular; Chemical and Drug Induced Liv

1973
Tumors in CF-1 mice exposed for six consecutive generations to DDT.
    Journal of the National Cancer Institute, 1973, Volume: 51, Issue:3

    Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; DDT; Diet; Liver Neoplasms; Lung Neoplasms; Mice; N

1973
Malignant mouse-liver tumors resembling human hepatoblastomas.
    Journal of the National Cancer Institute, 1973, Volume: 51, Issue:5

    Topics: Animals; Carcinoma, Hepatocellular; DDT; Female; Liver Neoplasms; Male; Mice; Mice, Inbred Strains;

1973
The effect of long-term exposure to DDT on CF-1 MICE.
    International journal of cancer, 1972, Volume: 10, Issue:3

    Topics: Animals; Body Weight; Carcinoma, Hepatocellular; DDT; Dose-Response Relationship, Drug; Female; Fert

1972
Associations between tumor types in a large-scale carcinogenesis study of CF-1 mice.
    Journal of the National Cancer Institute, 1974, Volume: 52, Issue:1

    Topics: Adenoma; Age Factors; Animals; Bone Neoplasms; Carcinogens; Carcinoma, Hepatocellular; DDT; Female;

1974
The effects of long-term feeding of DDT to BALB-c mice.
    International journal of cancer, 1973, Volume: 11, Issue:3

    Topics: Adenoma; Animals; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Cysts; DDT; Die

1973
Liver tumours in CF-1 mice exposed for limited periods to technical DDT.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1974, Volume: 82, Issue:1

    Topics: Adipose Tissue; Administration, Oral; Animals; Carcinoma, Hepatocellular; DDT; Dose-Response Relatio

1974
Environmental carcinogens: is there a threshold of exposure?
    Clinical toxicology, 1974, Volume: 7, Issue:5

    Topics: Aflatoxins; Carcinogens; DDT; Dose-Response Relationship, Drug; Environmental Exposure; Homeopathy;

1974
Pollution and worldwide catastrophe.
    Nature, 1972, Apr-28, Volume: 236, Issue:5348

    Topics: Adipose Tissue; Adolescent; Adult; Aged; Air Pollution; Animals; Birds; Carcinogens; Child; Child, P

1972
Species differences in the acute toxicity and tissue distribution of DDT in mice and hamsters.
    Toxicology and applied pharmacology, 1974, Volume: 28, Issue:3

    Topics: Animals; Brain; Carbon Radioisotopes; Chromatography, Gas; Chromatography, Thin Layer; Cricetinae; D

1974
Evidence of antitumorigenic effects of DDT.
    Archives of environmental health, 1971, Volume: 23, Issue:3

    Topics: Animals; DDT; Diet; Enzyme Induction; Ependymoma; Liver; Liver Neoplasms; Male; Methylcholanthrene;

1971
Pesticide concentrations in the liver, brain and adipose tissue of terminal hospital patients.
    Food and cosmetics toxicology, 1968, Volume: 6, Issue:2

    Topics: Adipose Tissue; Arteriosclerosis; Brain Chemistry; Brain Neoplasms; Cerebral Hemorrhage; Chromatogra

1968
Synergism among oral carcinogens. I. Results of the simultaneous feeding of four tumorigens to rats.
    Toxicology and applied pharmacology, 1965, Volume: 7, Issue:5

    Topics: Animals; Carcinogens; DDT; Drug Synergism; Female; In Vitro Techniques; Liver; Liver Neoplasms; Male

1965