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ddt and Disease Models, Animal

ddt has been researched along with Disease Models, Animal in 26 studies

1,1-bis(p-chlorophenyl)-2,2,2-trichloroethane: structure in first source

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
" Dose-response relations appear to be non-monotonic."2.50Obesogenic effects of endocrine disruptors, what do we know from animal and human studies? ( de Cock, M; van de Bor, M, 2014)
"The incidence of obesity has increased dramatically over the past two decades with a prevalence of approximately 40% of the adult population within the United States."1.51Adipocyte epigenetic alterations and potential therapeutic targets in transgenerationally inherited lean and obese phenotypes following ancestral exposures. ( Beck, D; King, SE; Nilsson, E; Skinner, MK, 2019)
" Further, when the human condition was simulated in animals, there was deprivation in body weight and glucose levels in starved litchi seed dosed rats, causing hypoglycemia."1.51Methylenecyclopropyl glycine, not pesticide exposure as the primary etiological factor underlying hypoglycemic encephalopathy in Muzaffarpur, India. ( Asthana, S; Das, M; Dixit, S; Kumar, A; Singh, SP; Srivastava, A; Tripathi, A, 2019)
"The incidence of autoimmune Type 1 diabetes (T1D) has been steadily rising in developed countries."1.43Exposure to DDT metabolite p,p'-DDE increases autoimmune type 1 diabetes incidence in NOD mouse model. ( Cetkovic-Cvrlje, M; Gong, HK; Olson, M; Schindler, B, 2016)
"Treatment with chlordecone, methoxychlor, or o,p -dichlorodiphenyltrichloroethane (o,p -DDT) significantly decreased the time to onset of renal impairment, as did treatment with 17ss-estradiol used as a positive control."1.33Acceleration of autoimmunity by organochlorine pesticides in (NZB x NZW)F1 mice. ( Butfiloski, EJ; Croker, BP; Gianini, J; Roberts, SM; Schiffenbauer, J; Sobel, ES, 2005)
" To study the role of serotonin (5-HT) receptors in myoclonus induced by p,p'-DDT in the rat, we performed time-course and dose-response studies of the effects of p,p'-DDT on behavior and regional 5-HT1 and 5-HT2 binding sites."1.29p,p'-DDT myoclonic/epileptic model: serotonin receptor binding and behavioral studies in the rat. ( Gonzales, W; Pluchino, R; Pranzatelli, MR; Simmens, S; Tailor, PT, 1994)
"Gabapentin dose-dependently attenuated myoclonus in posthypoxic rats for more than 3 h."1.29Antimyoclonic effect of gabapentin in a posthypoxic animal model of myoclonus. ( Kanthasamy, AG; Truong, DD; Vu, TQ; Yun, RJ, 1996)
"Lower DDT doses, which also induced myoclonus, had no significant effects on [3H]strychnine specific binding."1.28Regional glycine receptor binding in the p,p'-DDT myoclonic rat model. ( Pranzatelli, MR; Tkach, K, 1992)
"p,p'-DDT-induced myoclonus in mice has been proposed as a model of stimulus-sensitive action myoclonus responsive to L-5-HTP and clonazepam treatment."1.27p,p'-DDT-induced myoclonus in the rat and its application as an animal model of 5-HT-sensitive action myoclonus. ( Jenner, P; Marsden, CD; Pratt, JA; Rothwell, J, 1986)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19909 (34.62)18.7374
1990's3 (11.54)18.2507
2000's5 (19.23)29.6817
2010's7 (26.92)24.3611
2020's2 (7.69)2.80

Authors

AuthorsStudies
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Eid, A1
Mhatre-Winters, I1
Sammoura, FM1
Edler, MK1
von Stein, R1
Hossain, MM1
Han, Y1
Lisci, M1
Carney, K1
Konsolaki, M1
Hart, RP1
Bennett, JW1
Richardson, JR1
King, SE1
Nilsson, E1
Beck, D1
Skinner, MK1
Asthana, S1
Dixit, S1
Srivastava, A1
Kumar, A1
Singh, SP1
Tripathi, A1
Das, M1
de Cock, M1
van de Bor, M1
Shimada, Y1
Tomita, M1
Yoshida, T1
Fukuyama, T1
Katoh, Y1
Ohnuma-Koyama, A1
Takahashi, N1
Soma, K1
Kojima, S1
Ohtsuka, R1
Takeda, M1
Kuwahara, M1
Harada, T1
Cetkovic-Cvrlje, M1
Olson, M1
Schindler, B1
Gong, HK1
Ramsdell, JS2
Johnson, NA1
Ho, A1
Cline, JM1
Hughes, CL1
Foster, WG1
Davis, VL1
Gray, LE1
Ostby, J1
Furr, J1
Wolf, C1
Lambright, C1
Wilson, V1
Noriega, N1
Sobel, ES1
Gianini, J1
Butfiloski, EJ1
Croker, BP1
Schiffenbauer, J1
Roberts, SM1
Kushida, M1
Sukata, T1
Uwagawa, S1
Ozaki, K1
Kinoshita, A1
Wanibuchi, H1
Morimura, K1
Okuno, Y1
Fukushima, S1
Brown, K1
Pranzatelli, MR2
Tailor, PT1
Pluchino, R1
Gonzales, W1
Simmens, S1
Kanthasamy, AG1
Vu, TQ1
Yun, RJ1
Truong, DD1
Edmunds, JS1
McCarthy, RA1
Deichman, WB1
Cranmer, MF1
Bessey, O1
Epstein, SS1
Tkach, K1
Pratt, JA1
Rothwell, J1
Jenner, P1
Marsden, CD1
Chapman, AG1
Slem, G1
Ayan, Y1
Baykal, E1
Lukaneva, AM1
Rodionov, GA1
Arsen'eva, MV1

Reviews

5 reviews available for ddt and Disease Models, Animal

ArticleYear
Obesogenic effects of endocrine disruptors, what do we know from animal and human studies?
    Environment international, 2014, Volume: 70

    Topics: Animals; DDT; Disease Models, Animal; Endocrine Disruptors; Humans; Hydrocarbons, Chlorinated; Mice;

2014
Neurological disease rises from ocean to bring model for human epilepsy to life.
    Toxins, 2010, Volume: 2, Issue:7

    Topics: Animals; DDT; Disease Models, Animal; Epilepsy; Humans; Kainic Acid; Marine Toxins; Neurotoxins; Pes

2010
Toxicant-induced hypospadias in the male rat.
    Advances in experimental medicine and biology, 2004, Volume: 545

    Topics: Androgen Antagonists; Androgen Receptor Antagonists; Animals; Bridged Bicyclo Compounds; DDT; Dichlo

2004
The carcinogenicity of dieldrin. Part I.
    The Science of the total environment, 1975, Volume: 4, Issue:1

    Topics: Animals; Carcinogens; DDT; Dieldrin; Disease Models, Animal; Dogs; Drug Interactions; Epidemiology;

1975
Valproate and myoclonus.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Aspartic Acid; Clonazepam; DDT; Disease Models, Animal; F

1986

Other Studies

21 other studies available for ddt and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Effects of DDT on Amyloid Precursor Protein Levels and Amyloid Beta Pathology: Mechanistic Links to Alzheimer's Disease Risk.
    Environmental health perspectives, 2022, Volume: 130, Issue:8

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; DDT; Dichlorodiph

2022
Adipocyte epigenetic alterations and potential therapeutic targets in transgenerationally inherited lean and obese phenotypes following ancestral exposures.
    Adipocyte, 2019, Volume: 8, Issue:1

    Topics: Adipocytes; Adipose Tissue; Animals; Atrazine; DDT; Disease Models, Animal; DNA Methylation; Epigene

2019
Methylenecyclopropyl glycine, not pesticide exposure as the primary etiological factor underlying hypoglycemic encephalopathy in Muzaffarpur, India.
    Toxicology letters, 2019, Volume: 301

    Topics: Acute Disease; Acute Febrile Encephalopathy; Animals; Cyclopropanes; DDT; Disease Models, Animal; Fr

2019
Inhibition of lipopolysaccharide-induced liver injury in rats treated with a hepatic drug-metabolizing enzyme inducer p,p'-DDT.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2015, Volume: 67, Issue:3

    Topics: Animals; Chemical and Drug Induced Liver Injury; DDT; Disease Models, Animal; Lipopolysaccharides; L

2015
Exposure to DDT metabolite p,p'-DDE increases autoimmune type 1 diabetes incidence in NOD mouse model.
    Journal of immunotoxicology, 2016, Volume: 13, Issue:1

    Topics: Animals; Autoimmune Diseases; Cells, Cultured; Cytokines; DDT; Diabetes Mellitus, Type 1; Dichlorodi

2016
Accelerated mammary tumor onset in a HER2/Neu mouse model exposed to DDT metabolites locally delivered to the mammary gland.
    Environmental health perspectives, 2012, Volume: 120, Issue:8

    Topics: Animals; DDT; Disease Models, Animal; Genes, erbB-2; Mammary Neoplasms, Experimental; Mice

2012
Acceleration of autoimmunity by organochlorine pesticides in (NZB x NZW)F1 mice.
    Environmental health perspectives, 2005, Volume: 113, Issue:3

    Topics: Animals; Autoimmunity; Chlordecone; DDT; Disease Models, Animal; Estrogens, Non-Steroidal; Female; I

2005
Low dose DDT inhibition of hepatocarcinogenesis initiated by diethylnitrosamine in male rats: possible mechanisms.
    Toxicology and applied pharmacology, 2005, Nov-01, Volume: 208, Issue:3

    Topics: Administration, Oral; Animals; Apoptosis; Cell Proliferation; Connexins; Cytochrome P-450 Enzyme Sys

2005
From Ubombo to Mkhuzi: disease, colonial science, and the control of Nagana (livestock trypanosomosis) in Zululand, South Africa, C. 1894-1953.
    Journal of the history of medicine and allied sciences, 2008, Volume: 63, Issue:3

    Topics: Animals; Cattle; Colonialism; DDT; Disease Models, Animal; History, 19th Century; History, 20th Cent

2008
p,p'-DDT myoclonic/epileptic model: serotonin receptor binding and behavioral studies in the rat.
    Neurotoxicology, 1994,Summer, Volume: 15, Issue:2

    Topics: 5,7-Dihydroxytryptamine; Animals; Behavior, Animal; DDT; Disease Models, Animal; Epilepsies, Myoclon

1994
Antimyoclonic effect of gabapentin in a posthypoxic animal model of myoclonus.
    European journal of pharmacology, 1996, Feb-22, Volume: 297, Issue:3

    Topics: Acetates; Acoustic Stimulation; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; DDT;

1996
Permanent and functional male-to-female sex reversal in d-rR strain medaka (Oryzias latipes) following egg microinjection of o,p'-DDT.
    Environmental health perspectives, 2000, Volume: 108, Issue:3

    Topics: Animals; Breeding; DDT; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, P

2000
Cummings Memorial Lecture - 1975. The market basket: food for thought.
    American Industrial Hygiene Association journal, 1975, Volume: 36, Issue:6

    Topics: Aldrin; Animals; Carcinogens; DDT; Dieldrin; Disease Models, Animal; Dose-Response Relationship, Dru

1975
Estimation of risks due to environmental carcinogenesis.
    Medical and pediatric oncology, 1977, Volume: 3, Issue:2

    Topics: Aflatoxins; Animals; Benzidines; Carcinogens, Environmental; DDT; Diethylstilbestrol; Disease Models

1977
Status of marine biomedical research.
    Environmental health perspectives, 1976, Volume: 13

    Topics: Animals; Brain; Carcinogens; Cells, Cultured; DDT; Dinoflagellida; Disease Models, Animal; Disease V

1976
Regional glycine receptor binding in the p,p'-DDT myoclonic rat model.
    Archives of toxicology, 1992, Volume: 66, Issue:1

    Topics: Animals; Brain Stem; DDT; Disease Models, Animal; Male; Myoclonus; Rats; Rats, Inbred Strains; Recep

1992
p,p'-DDT-induced myoclonus in the rat and its application as an animal model of 5-HT-sensitive action myoclonus.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Clonazepam; DDT; Disease Models, Animal; Elec

1986
Experimental study on the effects of insecticides on the rabbit eye.
    Annals of ophthalmology, 1972, Volume: 4, Issue:10

    Topics: Animals; Atrophy; Conjunctivitis; Copper; Corneal Ulcer; DDT; Disease Models, Animal; Eye; Eye Disea

1972
[Some experimental data on the effect of DDT and Sevin on the development of cholesterol arteriosclerosis].
    Gigiena i sanitariia, 1973, Volume: 38, Issue:9

    Topics: Animals; Arteriosclerosis; Carbaryl; Cholesterol; DDT; Disease Models, Animal; Female; Male; Rabbits

1973
[Comparative evaluation of the toxicity of DDT and uranium for intact animals and for animals with experimental hepatitis and nephritis].
    Gigiena i sanitariia, 1972, Volume: 37, Issue:10

    Topics: Acute Disease; Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chro

1972