ddt has been researched along with Carcinoma, Hepatocellular in 19 studies
1,1-bis(p-chlorophenyl)-2,2,2-trichloroethane: structure in first source
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dichlorodiphenyltrichloroethane (p,p'-DDT), an organochlorine pesticide known to have deleterious health effects in humans, has been linked to hepatocellular carcinoma (HCC) in rodents." | 3.78 | Dichlorodiphenyltrichloroethane and risk of hepatocellular carcinoma. ( Chen, G; Evans, AA; Graubard, BI; LeBlanc, A; Lin, W; London, WT; McGlynn, KA; Persson, EC; Weber, JP, 2012) |
| "Eligibility criteria included examining hepatocellular carcinoma (HCC) or primary liver cancer, pesticides as an exposure of interest, and individual-level incidence." | 2.55 | Pesticide exposure and liver cancer: a review. ( Bertrand, KA; Brooks, MM; Chang, CH; Hart, JE; Laden, F; Ruddell, D; Talbott, EO; VoPham, T; Weissfeld, JL; Yuan, JM, 2017) |
| "Flutamide was a complete agonist, whereas its hydroxylated metabolite, hydroxyflutamide, only partially antagonized and displayed some agonist activity at 10(-6) M and above." | 1.30 | Inhibition of androgen receptor-dependent transcriptional activity by DDT isomers and methoxychlor in HepG2 human hepatoma cells. ( Gaido, KW; Maness, SC; McDonnell, DP, 1998) |
| "Hepatomas were found to be predominant neoplasm, observed at a frequency that decreased from 5." | 1.26 | Hepatomas and other neoplasms in the atlantic hagfish (Myxine glutinosa): a histopathologic and chemical study. ( Falkmer, S; Marklund, S; Mattsson, PE; Rappe, C, 1978) |
| "DDT is a pesticide used in malaria-control programmes throughout the world." | 1.26 | Effects of long-term intake of DDT on rats. ( Bronczyk, SA; Cabral, JR; Hall, RK; Rossi, L; Shubik, P, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (68.42) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 3 (15.79) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jin, XT | 1 |
| Song, L | 1 |
| Zhao, JY | 1 |
| Li, ZY | 1 |
| Zhao, MR | 1 |
| Liu, WP | 1 |
| VoPham, T | 1 |
| Bertrand, KA | 1 |
| Hart, JE | 1 |
| Laden, F | 1 |
| Brooks, MM | 1 |
| Yuan, JM | 1 |
| Talbott, EO | 1 |
| Ruddell, D | 1 |
| Chang, CH | 1 |
| Weissfeld, JL | 1 |
| Persson, EC | 1 |
| Graubard, BI | 1 |
| Evans, AA | 1 |
| London, WT | 1 |
| Weber, JP | 1 |
| LeBlanc, A | 1 |
| Chen, G | 1 |
| Lin, W | 1 |
| McGlynn, KA | 1 |
| Medina-Díaz, IM | 1 |
| Elizondo, G | 1 |
| Cabral, JR | 1 |
| Hall, RK | 1 |
| Rossi, L | 1 |
| Bronczyk, SA | 1 |
| Shubik, P | 3 |
| Maness, SC | 1 |
| McDonnell, DP | 1 |
| Gaido, KW | 1 |
| Tilak, TB | 1 |
| Nagarajan, V | 1 |
| Tulpule, PG | 1 |
| Falkmer, S | 1 |
| Marklund, S | 1 |
| Mattsson, PE | 1 |
| Rappe, C | 1 |
| Turusov, VS | 4 |
| Khar'kovskaia, NA | 1 |
| Kondalenko, VF | 1 |
| Poltoranina, VS | 1 |
| Svinolupova, SI | 1 |
| Khrustalev, SA | 1 |
| Engel'gardt, NV | 1 |
| Agthe, C | 1 |
| Garcia, H | 1 |
| Tomatis, L | 5 |
| Wenyon, E | 1 |
| Khudoleĭ, VV | 1 |
| Walker, AI | 1 |
| Thorpe, E | 1 |
| Stevenson, DE | 1 |
| Day, NE | 2 |
| Gati, E | 2 |
| Charles, RT | 3 |
| Deringer, MK | 1 |
| Dunn, TB | 1 |
| Stewart, HL | 1 |
| Turusov, V | 2 |
| Day, N | 2 |
| Breslow, NE | 1 |
| Terracini, B | 1 |
| Testa, MC | 1 |
| Carbral, JR | 1 |
| Boiocchi, M | 1 |
3 reviews available for ddt and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Pesticide exposure and liver cancer: a review.
Topics: Biomarkers; Carcinoma, Hepatocellular; China; DDT; Egypt; Environmental Exposure; Humans; Liver Neop | 2017 |
Microsomal metabolism as a determinant of aflatoxin toxicity.
Topics: Aflatoxins; Animals; Carcinoma, Hepatocellular; DDT; Dose-Response Relationship, Drug; Liver Neoplas | 1975 |
[Experimental neoplasms in fish].
Topics: Aflatoxins; Animal Feed; Animals; Benz(a)Anthracenes; Carcinogens; Carcinoma, Hepatocellular; Catara | 1971 |
16 other studies available for ddt and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Dichlorodiphenyltrichloroethane exposure induces the growth of hepatocellular carcinoma via Wnt/β-catenin pathway.
Topics: Animals; Antioxidants; beta Catenin; Carcinogens; Carcinoma, Hepatocellular; Cell Proliferation; Cyc | 2014 |
Dichlorodiphenyltrichloroethane and risk of hepatocellular carcinoma.
Topics: Adult; Carcinoma, Hepatocellular; Case-Control Studies; Cohort Studies; DDT; Dichlorodiphenyl Dichlo | 2012 |
Transcriptional induction of CYP3A4 by o,p'-DDT in HepG2 cells.
Topics: Carcinoma, Hepatocellular; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DDT; Dose-Respons | 2005 |
Effects of long-term intake of DDT on rats.
Topics: Animals; Carcinoma, Hepatocellular; DDT; Female; Liver Neoplasms; Male; Neoplasms, Experimental; Rat | 1982 |
Inhibition of androgen receptor-dependent transcriptional activity by DDT isomers and methoxychlor in HepG2 human hepatoma cells.
Topics: Androgen Antagonists; Androgen Receptor Antagonists; Androgens; Antineoplastic Agents, Hormonal; Car | 1998 |
Hepatomas and other neoplasms in the atlantic hagfish (Myxine glutinosa): a histopathologic and chemical study.
Topics: Adenoma, Bile Duct; Animals; Carcinogens, Environmental; Carcinoma, Hepatocellular; DDT; Fish Diseas | 1978 |
[Mouse hepatoblastoma: comparative aspects].
Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; DDT; Liver Neoplasms; Liver Neoplasms, Experimental | 1991 |
Study of the potential carcinogenicity of DDT in the Syrian golden hamster.
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Adenoma; Adrenal Gland Neoplasms; Animals; Body | 1970 |
The use of the Syrian golden hamster in chronic toxicity testing.
Topics: Animals; Azo Compounds; Benz(a)Anthracenes; Carcinogens; Carcinoma, Hepatocellular; Carcinoma, Squam | 1972 |
The toxicology of dieldrin (HEOD). I. Long-term oral toxicity studies in mice.
Topics: Administration, Oral; Animals; Body Weight; Carcinoma, Hepatocellular; Chemical and Drug Induced Liv | 1973 |
Tumors in CF-1 mice exposed for six consecutive generations to DDT.
Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; DDT; Diet; Liver Neoplasms; Lung Neoplasms; Mice; N | 1973 |
Malignant mouse-liver tumors resembling human hepatoblastomas.
Topics: Animals; Carcinoma, Hepatocellular; DDT; Female; Liver Neoplasms; Male; Mice; Mice, Inbred Strains; | 1973 |
The effect of long-term exposure to DDT on CF-1 MICE.
Topics: Animals; Body Weight; Carcinoma, Hepatocellular; DDT; Dose-Response Relationship, Drug; Female; Fert | 1972 |
Associations between tumor types in a large-scale carcinogenesis study of CF-1 mice.
Topics: Adenoma; Age Factors; Animals; Bone Neoplasms; Carcinogens; Carcinoma, Hepatocellular; DDT; Female; | 1974 |
The effects of long-term feeding of DDT to BALB-c mice.
Topics: Adenoma; Animals; Carcinoma, Hepatocellular; Chemical and Drug Induced Liver Injury; Cysts; DDT; Die | 1973 |
Liver tumours in CF-1 mice exposed for limited periods to technical DDT.
Topics: Adipose Tissue; Administration, Oral; Animals; Carcinoma, Hepatocellular; DDT; Dose-Response Relatio | 1974 |