Page last updated: 2024-10-26

ddt and Alzheimer Disease

ddt has been researched along with Alzheimer Disease in 4 studies

1,1-bis(p-chlorophenyl)-2,2,2-trichloroethane: structure in first source

Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Research Excerpts

ExcerptRelevanceReference
"Both DDT and DDE increase amyloid precursor protein levels, providing mechanistic plausibility for the association of DDE exposure with AD."1.40Elevated serum pesticide levels and risk for Alzheimer disease. ( Buckley, B; Gearing, M; German, DC; Hossain, MM; Levey, AI; Richardson, JR; Roy, A; Shalat, SL; von Stein, RT, 2014)
"Dieldrin was detected in 6 of 20 PD brains, 1 of 7 AD, and in none of 14 control samples."1.29Parkinson's disease and brain levels of organochlorine pesticides. ( Bean, J; Briggle, T; Fleming, L; Mann, JB; Sanchez-Ramos, JR, 1994)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Eid, A1
Mhatre-Winters, I1
Sammoura, FM1
Edler, MK1
von Stein, R1
Hossain, MM2
Han, Y1
Lisci, M1
Carney, K1
Konsolaki, M1
Hart, RP1
Bennett, JW1
Richardson, JR2
Kiani, Z1
Asadikaram, G1
Faramarz, S1
Salimi, F1
Ebrahimi, H1
Roy, A1
Shalat, SL1
von Stein, RT1
Buckley, B1
Gearing, M1
Levey, AI1
German, DC1
Fleming, L1
Mann, JB1
Bean, J1
Briggle, T1
Sanchez-Ramos, JR1

Other Studies

4 other studies available for ddt and Alzheimer Disease

ArticleYear
Effects of DDT on Amyloid Precursor Protein Levels and Amyloid Beta Pathology: Mechanistic Links to Alzheimer's Disease Risk.
    Environmental health perspectives, 2022, Volume: 130, Issue:8

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; DDT; Dichlorodiph

2022
Pesticide Exposure and Alzheimer's Disease: A Case-control Study.
    Current Alzheimer research, 2023, Volume: 19, Issue:13

    Topics: Acetylcholinesterase; Alzheimer Disease; Antioxidants; Aryldialkylphosphatase; Case-Control Studies;

2023
Elevated serum pesticide levels and risk for Alzheimer disease.
    JAMA neurology, 2014, Volume: 71, Issue:3

    Topics: Aged; Aged, 80 and over; Alleles; Alzheimer Disease; Amyloid beta-Peptides; Apolipoprotein E3; Apoli

2014
Parkinson's disease and brain levels of organochlorine pesticides.
    Annals of neurology, 1994, Volume: 36, Issue:1

    Topics: Age Factors; Aged; Alzheimer Disease; Brain Chemistry; Cross-Sectional Studies; DDT; Dieldrin; Femal

1994