Compounds > daunorubicin
Page last updated: 2024-08-23

daunorubicin and Lung Neoplasms

daunorubicin has been researched along with Lung Neoplasms in 110 studies

Research

Studies (110)

TimeframeStudies, this research(%)All Research%
pre-199048 (43.64)18.7374
1990's40 (36.36)18.2507
2000's15 (13.64)29.6817
2010's7 (6.36)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Broxterman, HJ; Feller, N; Lankelma, J; Pinedo, HM; Versantvoort, CH1
Almquist, KC; Cole, SP; Deeley, RG; Loe, DW1
Chen, YL; Chen, YW; Liang, CC; Lu, PJ; Tseng, CH; Tzeng, CC; Yang, CN; Yao, YC1
Chen, YL; Chiu, CC; Chou, CK; Hsu, CY; Tseng, CH; Tzeng, CC1
Chmielewska, K; Kluska, M; Pietrzak, J; Robaszkiewicz, A; Rygielska, Ż; Tempka, D; Tokarz, P; Virág, L1
Fan, L; Fu, M; Li, G; Li, J; Li, X; Liu, J; Pan, W; Wang, X; Wang, Y; Yang, Y; Yu, Y1
Ahmad, R; Hahn, YB; Khang, G; Ko, HA; Tripathy, N1
Cai, YD; Chen, L; Huang, T; Kong, X; Yang, J; Zheng, M1
Altman, J; Kuzel, T; Parajuli, R; Perdekamp, M; Tallman, M1
Bosch, SV; de Jonge, MJ; Fiorentini, F; Hess, D; Lechuga, MJ; Mantel, MA; Mora, O; Planting, AS; Sessa, C; Valota, O; van der Gaast, A; Verweij, J1
Coleman, A; Kane, SE; Sadava, D1
DUBOST, M; GANTER, P; MARAL, R; NINET, L; PINNERT, S; PREUDHOMME, J; WERNER, GH2
Boronovskaia, LE; Korman, DB; Maslova, IA; Mikaélian, SG1
Mossink, MH; Scheper, RJ; Schoester, M; Sonneveld, P; van Zon, A; Wiemer, EA1
Corona, G; Crivellari, D; Lestuzzi, C; Lombardi, D; Lucenti, A; Magri, MD; Massacesi, C; Sorio, R; Talamini, R; Toffoli, G; Veronesi, A1
Kitazawa, R; Kitazawa, S; Kondo, T; Nishimura, Y; Obayashi, C1
Arnon, R; Hurwitz, E; Sela, M1
Umezawa, H1
Chebotareva, LI; Garin, AM; Guznov, GI; Moroz, LV; Prorokov, VV1
Alberto, P; Cavalli, F; Joss, RA; Obrecht, JP; Siegenthaler, P; VanHelvoirt, A1
Dawson, KM1
Bizer, VA; Timukhina, VN1
Myers, CE; Ozols, RF; Young, RC1
Bucciarelli, E; Miele Bianco, F; Provvidenza, M; Testarella, M1
Bagrij, T; Broxterman, HJ; Scheper, RJ; Twentyman, PR; Versantvoort, CH1
Broxterman, HJ; de Vries, EG; Kuiper, CM; Mulder, NH; Scheper, RJ; Versantvoort, CH; Withoff, S1
Beck, J; Gekeler, V; Ise, W; Sanders, KH; Ulrich, WR1
Dekker, H; Lankelma, J; Pinedo, HM; Spoelstra, EC; Westerhoff, HV1
Barrand, MA; Rhodes, T; Twentyman, PR1
Broxterman, HJ; Dekker, H; Lankelma, J; Mülder, HS; Pinedo, HM1
Dormann, A; Grünewald, T; Ruf, B; Schürmann, D1
Christensen, IJ; Hansen, HH; Jensen, PB; Sehested, M; Vindeløv, L1
Blayney, DW; Flanagan, B; Kennedy, P; Lisak, J; Presant, CA; Presant, J; Scolaro, M1
Broxterman, HJ; Eekman, CA; Kuiper, CM; Lankelma, J; Pinedo, HM; Schuurhuis, GJ; Versantvoort, CH1
Andreoni, A; Colasanti, A; Kisslinger, A; Mastrocinque, M; Riccio, P; Roberti, G1
Lankelma, J; Mülder, HS; van Grondelle, R; Westerhoff, HV1
Chan, JC; Chan, JK; Lam, SY; Wong, KF1
Andreoni, A; Colasanti, A; Kisslinger, A; Mastrocinque, M; Portella, G; Riccio, P; Roberti, G1
Ikeda, K; Kubota, Y; Murata, M; Nagai, M; Ohnishi, H; Sasaki, K; Takahara, J; Tanaka, T; Taoka, T; Tasaka, T1
Barrand, MA; Center, MS; Rhodes, T; Twentyman, PR1
Fernández Puentes, JL; García Grávalos, MD; Quesada, AR1
Alvord, WG; Gazdar, AF; Gray-Goodrich, M; Koo, HM; McWilliams, MJ; Mikheev, A; Monks, A; Oie, HK; Paull, KD; Rubinstein, LV; Vande Woude, GF; Zarbl, H1
Das, KC; White, CW1
Forman, SJ; Margolin, KA; Wright, C1
Dupont, B; Eliaszewicz, M; Feuillie, V; Fournier, S; Gonzalez-Canali, G; Pialoux, G1
Berger, W; Elbling, L; Hauptmann, E; Micksche, M1
Broxterman, HJ; Dubru, F; Garnier-Suillerot, A; Marbeuf-Gueye, C; Priebe, W1
Bergman, AM; Kuiper, CM; Peters, GJ; Pinedo, HM; Veerman, G1
Benderra, Z; Manfait, M; Morjani, H; Trussardi, A1
Boswell, W; Cabriales, S; Espina, BM; Gill, PS; Ilaw, M; Myers, A; Scadden, DT; Tulpule, A; Wernz, J; Yung, RC1
Horie, T; Masutani, M; Sawada, U; Tsujino, I; Yamazaki, T1
de Vries, EG; Eriks-Fluks, L; Franssen, EJ; Hendrikse, NH; Hospers, GA; Vaalburg, W; van der Graaf, WT; Willemsen, AT1
Honma, Y; Kasukabe, T; Niitsu, N; Okabe-Kado, J; Umeda, M; Yamamoto-Yamaguchi, Y; Yokoyama, A1
Berger, W; Elbling, L; Micksche, M1
Davey, M; Davey, R; Locke, V1
Bergman, AM; Jensen, PB; Munch-Petersen, B; Peters, GJ; Pinedo, HM; Sehested, M; Smid, K; Veerman, G; Voorn, DA1
Birbes, H; Hannun, YA; Kraveka, JM; Luberto, C; Obeid, LM; Ogretmen, B; Schady, D; Usta, J; Wood, R1
Garnier-Suillerot, A; Salerno, M1
Erikson, C; Florschütz, A; Rosahl, W; Schreiber, J; Schumann, HJ; Zugehör, M1
Baptiste, N; Chen, X; Friedlander, P; Prives, C1
Chen, L; Liu, Y1
Bloomer, WD; Horwich, A; Lokich, JJ1
Kawakubo, Y; Komiyama, K; Nishiyama, Y; Umezawa, I1
Hinderer, H; Kaufmann, M; Mattern, J; Volm, M; Wayss, K1
Baker, LH; Buroker, TR; Fraile, RJ; O'Bryan, R; Samson, MK; Vaitkevicius, VK1
Bosly, A; Cornu, G; Ferrant, A; Hulhoven, R; Michaux, JL; Sokal, G1
Arnon, R; Hurwitz, E; Schechter, B; Sela, M1
Barinov, VV; Savinova, VF1
Broggini, M; Colombo, T; Donelli, MG; Garattini, S1
Goldin, A; Johnson, RK; Ovejera, AA1
Donelli, NG; Fogar-Ottaviano, EF; Garattini, S; Mantovani, A; Martini, A; Morasca, L; Pacciarini, MA; Spreafico, FS1
Kaufmann, M; Mattern, J; Volm, M; Wayss, K1
Galochkina, ZI; Kinzirskiĭ, AS; Koroleva, AM; Mikhaĭlevskaia, LL1
Broxterman, HJ; de Vries, EG; Feller, N; Kuiper, CM; Lankelma, J; Pinedo, HM; Versantvoort, CH1
Baas, F; Borst, P; de Jong, S; de Vries, EG; Eijdems, EW; Jongsma, AP; Nieuwint, AW; van Groenigen, M; Versantvoort, CH1
De Luise, M; Hu, XF; Huggins, R; Martin, TJ; Nadalin, G; Wakeling, A; Zalcberg, JR1
Demant, EJ; Friche, E; Hansen, HH; Jensen, PB; Jensen, PS; Sehested, M; Sørensen, BS; Vindeløv, L; Wassermann, K; Westergaard, O1
Coley, HM; Twentyman, PR; Workman, P1
Izumi, H; Shirai, M; Yamagami, T1
Matsuo, K; Sugimoto, Y; Takeda, S; Tsukagoshi, S; Yamada, Y1
Diener, E; Ding, L; Longenecker, BM; MacLean, GD; Noujaim, AA; Samuel, J1
Cole, SP; Gerlach, JH; Mirski, SE1
Broxterman, HJ; Joenje, H; Keizer, HG; Lankelma, J; Pinedo, HM; Schoonen, WG; Schuurhuis, GJ; van Rijn, J1
Demant, EJ; Hansen, HH; Jensen, PB; Roed, H; Sehested, M; Skovsgaard, T; Vindeløv, L1
Benfield, GF; Cullen, MH; Smith, SR; Woodroffe, CM1
Dombernowsky, P; Hansen, M; Joss, RA; Monfardini, S; Pinedo, HM; Renard, J1
Kerstjens, HA; Lo, GT; Meinesz, AF; Postmus, PE; Sleijfer, DT; Sluiter, HJ1
Korman, DB; Krutova, TV; Pashkova, VS; Potapov, IuN1
Baurain, R; Ceulemans, F; Geubel, A; Lesur, B; Rolin-van Swieten, D; Trouet, A1
Hiraki, S; Kimura, I; Miyamoto, H; Ohnoshi, T1
de Vries, EG; Le, TK; Meijer, C; Mulder, NH; Timmer-Bosscha, H; Zijlstra, JG1
Banham, SW; Cummings, J; Kaye, SB; Milroy, R2
Boschetti, E; Daussin, F; Delmotte, F; Monsigny, M1
Hynds, SA; Kaye, SB; Kerr, DJ; Packard, CJ; Shepherd, J1
Kaye, SB; Kerr, AM; Kerr, DJ; Wheldon, TE1
Blum, RH; Green, MD; Hochster, HS; Muggia, FM; Speyer, JL; Wernz, JC1
Davila, E; Krishan, A; Sridhar, KS; Sternheim, W; Vogel, C1
Burke, MT; Casper, ES; Cibas, IR; Fiore, JJ; Gralla, RJ; Heelan, RT; Kelsen, DP; Kris, MG1
Benjamin, RS; Chawla, SP; Legha, SS1
Oara, H; Wada, T1
Atanasian, LA; Savinova, VF; Toloknov, BO1
Selawry, OS1
Ferrari, A; Garsia, SA; Mangioni, C; Molteni, P; Natale, N; Remotti, G1
Praga, C1
Chauvergne, J1
Cronin, AP; Philips, FS; Sternberg, SS1
Brulé, G; Kenis, Y1

Reviews

3 review(s) available for daunorubicin and Lung Neoplasms

ArticleYear
The anthracycline antineoplastic drugs.
    The New England journal of medicine, 1981, Jul-16, Volume: 305, Issue:3

    Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Breast Neoplasms; Carubicin; Daunorubicin; Doxorubicin; Female; Glycosides; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma; Naphthacenes; Ovarian Neoplasms; Sarcoma

1981
[Tumors].
    Naika. Internal medicine, 1972, Volume: 29, Issue:1

    Topics: Antigens; Bleomycin; Daunorubicin; Fetal Proteins; Fluorouracil; Glycolipids; Glycoproteins; Humans; Lung Neoplasms; Neoplasms; Radioimmunoassay; Radionuclide Imaging; Stomach Neoplasms

1972
Monochemotherapy of bronchogenic carcinoma withs special reference to cell type.
    Cancer chemotherapy reports. Part 3, 1973, Volume: 4, Issue:2

    Topics: Adenocarcinoma; Alkylating Agents; Antineoplastic Agents; Carcinoma, Bronchogenic; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Floxuridine; Humans; Hydroxyurea; Lung Neoplasms; Mechlorethamine; Methotrexate; Mitomycins; Nitrosourea Compounds; Plicamycin; Porfiromycin; Procarbazine; Streptonigrin; Thiotepa; Vinblastine

1973

Trials

10 trial(s) available for daunorubicin and Lung Neoplasms

ArticleYear
Phase I and pharmacokinetic studies of PNU-159548, a novel alkycycline, administered intravenously to patients with advanced solid tumours.
    European journal of cancer (Oxford, England : 1990), 2002, Volume: 38, Issue:18

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Daunorubicin; Dose-Response Relationship, Drug; Drug Hypersensitivity; Female; Hematologic Diseases; Humans; Lung Neoplasms; Male; Middle Aged; Nausea; Neoplasms; Vomiting

2002
[Results of a phase I-II clinical trial of Emoxyl, a novel antineoplastic anthracycline].
    Voprosy onkologii, 2004, Volume: 50, Issue:2

    Topics: Aged; Anthracyclines; Antibiotics, Antineoplastic; Breast Neoplasms; Carcinoma, Small Cell; Daunorubicin; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Middle Aged; Neoplasms; Sarcoma, Kaposi; Treatment Outcome

2004
Innovative schedule of oral idarubicin in elderly patients with metastatic breast cancer: comprehensive results of a phase II multi-institutional study with pharmacokinetic drug monitoring.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:5

    Topics: Administration, Oral; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Bone Neoplasms; Breast Neoplasms; Chromatography, High Pressure Liquid; Daunorubicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Monitoring; Female; Humans; Idarubicin; Liver Neoplasms; Lung Neoplasms; Soft Tissue Neoplasms

2006
[Adjuvant chemotherapy with carminomycin and bleomycetin after radical surgery for squamous cell carcinoma of the lung (preliminary communication)].
    Antibiotiki, 1982, Volume: 27, Issue:3

    Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Carubicin; Clinical Trials as Topic; Daunorubicin; Humans; Leukopenia; Lung Neoplasms; Male; Methotrexate; Middle Aged; Nausea; Vomiting

1982
Liposomal daunorubicin treatment of HIV-associated Kaposi's sarcoma.
    Lancet (London, England), 1993, May-15, Volume: 341, Issue:8855

    Topics: Acquired Immunodeficiency Syndrome; Adult; Daunorubicin; Drug Carriers; Humans; Liposomes; Lung Neoplasms; Pharyngeal Neoplasms; Quality of Life; Remission Induction; Sarcoma, Kaposi; Treatment Outcome

1993
Efficacy and tolerance of liposomal daunorubicin in Kaposi sarcoma associated with human immunodeficiency virus infection.
    Archives of dermatology, 1997, Volume: 133, Issue:7

    Topics: AIDS-Related Opportunistic Infections; Antibiotics, Antineoplastic; CD4 Lymphocyte Count; Daunorubicin; Digestive System Neoplasms; Disease Progression; Drug Carriers; Humans; Liposomes; Lung Neoplasms; Remission Induction; Sarcoma, Kaposi; Skin Neoplasms; Survival Rate

1997
Phase II trial of liposomal daunorubicin in the treatment of AIDS-related pulmonary Kaposi's sarcoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1998, Volume: 16, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adult; Antibiotics, Antineoplastic; Daunorubicin; Drug Administration Schedule; Humans; Liposomes; Lung; Lung Neoplasms; Male; Middle Aged; Prognosis; Prospective Studies; Sarcoma, Kaposi; Survival Analysis

1998
Clinical trial of rubidazone in advanced squamous cell carcinoma of the lung and adenocarcinoma of the large intestine.
    Cancer treatment reports, 1978, Volume: 62, Issue:10

    Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Squamous Cell; Clinical Trials as Topic; Colonic Neoplasms; Daunorubicin; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Middle Aged; Rectal Neoplasms

1978
Clinical trials with daunorubicin-DNA and adriamycin-DNA in acute lymphoblastic leukemia of childhood, acute nonlymphoblastic leukemia, and bronchogenic carcinoma.
    Cancer chemotherapy and pharmacology, 1979, Volume: 2, Issue:1

    Topics: Acute Disease; Carcinoma, Bronchogenic; Child; Clinical Trials as Topic; Daunorubicin; DNA; Doxorubicin; Humans; Leukemia; Leukemia, Lymphoid; Lung Neoplasms; Time Factors

1979
Phase II clinical and pharmacological study of oral 4-demethoxydaunorubicin in advanced non-pretreated small cell lung cancer.
    Cancer chemotherapy and pharmacology, 1987, Volume: 20, Issue:1

    Topics: Administration, Oral; Aged; Carcinoma, Small Cell; Clinical Trials as Topic; Daunorubicin; Drug Evaluation; Female; Humans; Idarubicin; Kinetics; Lung Neoplasms; Male; Middle Aged; Pilot Projects

1987

Other Studies

97 other study(ies) available for daunorubicin and Lung Neoplasms

ArticleYear
Competitive inhibition by genistein and ATP dependence of daunorubicin transport in intact MRP overexpressing human small cell lung cancer cells.
    Biochemical pharmacology, 1994, Sep-15, Volume: 48, Issue:6

    Topics: Adenosine Triphosphate; Biological Transport; Carcinoma, Small Cell; Daunorubicin; Drug Resistance; Genistein; Humans; Isoflavones; Lung Neoplasms; Tumor Cells, Cultured

1994
ATP-dependent 17 beta-estradiol 17-(beta-D-glucuronide) transport by multidrug resistance protein (MRP). Inhibition by cholestatic steroids.
    The Journal of biological chemistry, 1996, Apr-19, Volume: 271, Issue:16

    Topics: Adenosine Triphosphate; Animals; Antibodies, Monoclonal; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bile Acids and Salts; Binding, Competitive; Biological Transport; Carcinoma, Small Cell; Cell Line; Cell Membrane; Epitopes; Estradiol; Glucuronates; HeLa Cells; Humans; Kinetics; Leukotriene C4; Lung Neoplasms; Mice; Protein Conformation; Recombinant Proteins; Transfection; Tumor Cells, Cultured

1996
Discovery of 4-anilinofuro[2,3-b]quinoline derivatives as selective and orally active compounds against non-small-cell lung cancers.
    Journal of medicinal chemistry, 2011, Jul-14, Volume: 54, Issue:13

    Topics: Administration, Oral; Aniline Compounds; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Mice; Mice, Nude; Mitosis; Models, Molecular; Neoplasm Transplantation; Oximes; Quinolines; Solubility; Stereoisomerism; Structure-Activity Relationship; Tissue Distribution; Topoisomerase Inhibitors; Transplantation, Heterologous

2011
Discovery of 2-[2-(5-nitrofuran-2-yl)vinyl]quinoline derivatives as a novel type of antimetastatic agents.
    Bioorganic & medicinal chemistry, 2015, Jan-01, Volume: 23, Issue:1

    Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Discovery; Humans; Lung Neoplasms; Neoplasm Metastasis; Quinolines

2015
Downregulation of PARP1 transcription by CDK4/6 inhibitors sensitizes human lung cancer cells to anticancer drug-induced death by impairing OGG1-dependent base excision repair.
    Redox biology, 2018, Volume: 15

    Topics: Aminopyridines; Cell Cycle Checkpoints; Cell Line, Tumor; Cyclin-Dependent Kinase 4; Daunorubicin; DNA Damage; DNA Glycosylases; DNA Repair; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Peroxide; Lung Neoplasms; Piperazines; Poly (ADP-Ribose) Polymerase-1; Promoter Regions, Genetic; Purines; Pyridines

2018
Inhibition of tumor metastasis by targeted daunorubicin and dioscin codelivery liposomes modified with PFV for the treatment of non-small-cell lung cancer.
    International journal of nanomedicine, 2019, Volume: 14

    Topics: A549 Cells; Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Movement; Daunorubicin; Diosgenin; Drug Delivery Systems; Female; Humans; Liposomes; Lung Neoplasms; Matrix Metalloproteinase 2; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Oligopeptides; Particle Size; Static Electricity; Wound Healing

2019
Multi-synergetic ZnO platform for high performance cancer therapy.
    Chemical communications (Cambridge, England), 2015, Feb-14, Volume: 51, Issue:13

    Topics: Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Proliferation; Daunorubicin; Drug Carriers; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Particle Size; Porosity; Structure-Activity Relationship; Surface Properties; Zinc Oxide

2015
The Use of Chemical-Chemical Interaction and Chemical Structure to Identify New Candidate Chemicals Related to Lung Cancer.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Animals; Antineoplastic Agents; Arsenicals; Berberine; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Colchicine; Daunorubicin; Digoxin; Drug Discovery; Humans; Lung; Lung Neoplasms; Ouabain; Prednisone; Small Cell Lung Carcinoma; Tretinoin

2015
Renal cell carcinoma and acute promyelocytic leukemia: a nonrandom association?
    American journal of hematology, 2010, Volume: 85, Issue:10

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Colonic Neoplasms; Colonic Polyps; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Idarubicin; Indoles; Kidney Neoplasms; Leukemia, Promyelocytic, Acute; Lung Neoplasms; Male; Mercaptopurine; Methotrexate; Middle Aged; Neoplasms, Second Primary; Pyrroles; Remission Induction; Sunitinib; Time Factors; Tretinoin

2010
Liposomal daunorubicin overcomes drug resistance in human breast, ovarian and lung carcinoma cells.
    Journal of liposome research, 2002, Volume: 12, Issue:4

    Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma, Small Cell; Cell Death; Daunorubicin; Drug Resistance, Neoplasm; Female; Humans; Inhibitory Concentration 50; Liposomes; Lung Neoplasms; Ovarian Neoplasms; Tumor Cells, Cultured

2002
[A NEW ANTIBIOTIC WITH CYTOSTATIC PROPERTIES: RUBIDOMYCIN].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences, 1963, Sep-09, Volume: 257

    Topics: Adenocarcinoma; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Benzopyrenes; Carcinoma, Ehrlich Tumor; Daunorubicin; Leukemia; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Mice; Neoplasms; Research; Sarcoma 180; Sarcoma, Experimental; Streptomyces; Toxicology

1963
RUBIDOMYCIN: A NEW ANTIBIOTIC WITH CYTOSTATIC PROPERTIES.
    Cancer chemotherapy reports, 1964, Volume: 41

    Topics: Animals; Anti-Bacterial Agents; Carcinoma, Ehrlich Tumor; Daunorubicin; Leukemia; Leukemia, Experimental; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Mice; Neoplasms; Neoplasms, Experimental; Pathology; Research; Sarcoma 180; Sarcoma, Experimental; Toxicology

1964
Efflux kinetics and intracellular distribution of daunorubicin are not affected by major vault protein/lung resistance-related protein (vault) expression.
    Cancer research, 2004, Jul-15, Volume: 64, Issue:14

    Topics: Animals; Antibiotics, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Cell Line; Cell Nucleus; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Fibroblasts; Green Fluorescent Proteins; Humans; Luminescent Proteins; Lung Neoplasms; Male; Mice; Mice, Knockout; Recombinant Fusion Proteins; Transfection; Vault Ribonucleoprotein Particles

2004
Lung carcinosarcoma with liposarcoma element: autopsy case.
    Pathology international, 2006, Volume: 56, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Carboplatin; Carcinosarcoma; Cyclophosphamide; Daunorubicin; Fatal Outcome; Humans; Liposarcoma; Lung Neoplasms; Male; Middle Aged; Neoplasms, Multiple Primary; Radiography, Thoracic

2006
Antibodies as carriers for oncostatic materials.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1980, Volume: 75

    Topics: Animals; Antibodies; Antineoplastic Agents; Daunorubicin; Dextrans; In Vitro Techniques; Lung Neoplasms; Mice; Neoplasm Metastasis; Neoplasms, Experimental; Pharmaceutical Vehicles; Rabbits

1980
Recent studies on antibiotics and small molecular immunomodulators with potential usefulness in treating lung cancer: Part I - Antitumor antibiotics and their derivatives.
    International journal of clinical pharmacology, therapy, and toxicology, 1982, Volume: 20, Issue:1

    Topics: Aclarubicin; Adjuvants, Immunologic; Animals; Antibiotics, Antineoplastic; Bleomycin; Daunorubicin; Doxorubicin; Humans; Leukemia L1210; Lung; Lung Neoplasms; Mice; Molecular Weight; Naphthacenes; Peplomycin; Structure-Activity Relationship

1982
Phase II trial of 4-demethoxydaunorubicin in patients with non-small cell lung cancer.
    Cancer treatment reports, 1984, Volume: 68, Issue:3

    Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Daunorubicin; Digestive System; Drug Evaluation; Heart; Humans; Idarubicin; Leukopenia; Lung Neoplasms; Middle Aged

1984
Activity of SC33428, a novel bishydrazone-bridged derivative of 4-demethoxydaunorubicin, against experimental tumors in mice.
    Cancer research, 1983, Volume: 43, Issue:6

    Topics: Animals; Antineoplastic Agents; Daunorubicin; Doxorubicin; Idarubicin; Leukemia L1210; Leukemia P388; Lung Neoplasms; Melanoma; Mice; Neoplasms, Experimental

1983
[Treatment results in osteogenic sarcoma in children and adolescents with the use of karminomycin].
    Antibiotiki, 1984, Volume: 29, Issue:1

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Carubicin; Child; Child, Preschool; Combined Modality Therapy; Daunorubicin; Drug Evaluation; Follow-Up Studies; Humans; Lung Neoplasms; Lymphatic Metastasis; Melphalan; Osteosarcoma; Time Factors; Vincristine

1984
Lack of oncogenic activity of doxorubicin and daunorubicin in BALB/C mice.
    Tumori, 1982, Feb-28, Volume: 68, Issue:1

    Topics: Animals; Daunorubicin; Doxorubicin; Female; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasms, Experimental

1982
Regulation by glutathione of drug transport in multidrug-resistant human lung tumour cell lines overexpressing multidrug resistance-associated protein.
    British journal of cancer, 1995, Volume: 72, Issue:1

    Topics: Biological Transport; Buthionine Sulfoximine; Daunorubicin; Drug Resistance, Multiple; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Rhodamine 123; Rhodamines; RNA, Messenger; Tumor Cells, Cultured

1995
Resistance-associated factors in human small-cell lung-carcinoma GLC4 sub-lines with increasing adriamycin resistance.
    International journal of cancer, 1995, May-04, Volume: 61, Issue:3

    Topics: ATP-Binding Cassette Transporters; Base Sequence; Biological Transport; Carcinoma, Small Cell; Cell Division; Cell Line; Cell Membrane; Daunorubicin; DNA Primers; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance, Multiple; Etoposide; Gene Expression; Humans; Lung Neoplasms; Membrane Proteins; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Phosphorylation; Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Vincristine

1995
The leukotriene LTD4 receptor antagonist MK571 specifically modulates MRP associated multidrug resistance.
    Biochemical and biophysical research communications, 1995, Mar-08, Volume: 208, Issue:1

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Base Sequence; Carcinoma, Small Cell; Cell Line; Cell Survival; Clone Cells; Daunorubicin; DNA Primers; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Gene Expression; Humans; Leukemia, Promyelocytic, Acute; Leukotriene Antagonists; Lung Neoplasms; Membrane Proteins; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Polymerase Chain Reaction; Propionates; Quinolines; Receptors, Immunologic; Receptors, Leukotriene; Tumor Cells, Cultured; Vincristine

1995
The multidrug-resistance-reverser verapamil interferes with cellular P-glycoprotein-mediated pumping of daunorubicin as a non-competing substrate.
    European journal of biochemistry, 1994, Apr-01, Volume: 221, Issue:1

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Carcinoma, Non-Small-Cell Lung; Carrier Proteins; Culture Media; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance; Female; Humans; Kinetics; Lung Neoplasms; Membrane Glycoproteins; Models, Biological; Ovarian Neoplasms; Tumor Cells, Cultured; Verapamil

1994
Modification by brefeldin A, bafilomycin A1 and 7-chloro-4-nitrobenz-2-oxa-1,3-diazole (NBD) of cellular accumulation and intracellular distribution of anthracyclines in the non-P-glycoprotein-mediated multidrug-resistant cell line COR-L23/R.
    British journal of cancer, 1994, Volume: 70, Issue:1

    Topics: 4-Chloro-7-nitrobenzofurazan; Anti-Bacterial Agents; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brefeldin A; Carcinoma, Non-Small-Cell Lung; Carrier Proteins; Cell Nucleus; Cyclopentanes; Cytoplasm; Daunorubicin; Doxorubicin; Drug Interactions; Drug Resistance; Drug Screening Assays, Antitumor; Golgi Apparatus; Humans; Lung Neoplasms; Macrolides; Membrane Glycoproteins; Protein Synthesis Inhibitors; Proton-Translocating ATPases; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured

1994
Daunorubicin efflux against a concentration gradient in non-P-glycoprotein multidrug-resistant lung-cancer cells.
    International journal of cancer, 1994, Oct-15, Volume: 59, Issue:2

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Carcinoma, Non-Small-Cell Lung; Daunorubicin; Drug Interactions; Drug Resistance, Multiple; Humans; Hydrogen-Ion Concentration; Intracellular Fluid; Kinetics; Lung Neoplasms; Spectrometry, Fluorescence; Vincristine

1994
Successful treatment of AIDS-related pulmonary Kaposi's sarcoma with liposomal daunorubicin.
    The European respiratory journal, 1994, Volume: 7, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Adult; Daunorubicin; Humans; Liposomes; Lung Neoplasms; Male; Radiography; Sarcoma, Kaposi

1994
Differential cytotoxicity of 19 anticancer agents in wild type and etoposide resistant small cell lung cancer cell lines.
    British journal of cancer, 1993, Volume: 67, Issue:2

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Daunorubicin; DNA Topoisomerases, Type II; Drug Resistance; Drug Screening Assays, Antitumor; Etoposide; Humans; Lung Neoplasms; Membrane Glycoproteins; Tumor Cells, Cultured

1993
Genistein modulates the decreased drug accumulation in non-P-glycoprotein mediated multidrug resistant tumour cells.
    British journal of cancer, 1993, Volume: 68, Issue:5

    Topics: Alkaloids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carrier Proteins; Daunorubicin; Doxorubicin; Drug Resistance; Etoposide; Genistein; Humans; Hydrogen-Ion Concentration; Isoflavones; Lung Neoplasms; Membrane Glycoproteins; Neoplasms; Protein-Tyrosine Kinases; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

1993
Fluorometric determination of the kinetics of anthracyclines uptake by cells.
    Journal of biochemical and biophysical methods, 1994, Volume: 28, Issue:1

    Topics: Animals; Antineoplastic Agents; Cells, Cultured; Culture Media; Daunorubicin; Doxorubicin; Epithelial Cells; Epithelium; Extracellular Space; Fluorometry; Lipoproteins, LDL; Lung Neoplasms; Neoplasms; Rats; Spectrometry, Fluorescence; Thyroid Gland; Thyroid Neoplasms

1994
A plasma membrane 'vacuum cleaner' for daunorubicin in non-P-glycoprotein multidrug-resistant SW-1573 human non-small cell lung carcinoma cells. A study using fluorescence resonance energy transfer.
    European journal of biochemistry, 1993, Dec-15, Volume: 218, Issue:3

    Topics: Biological Transport; Carcinoma, Non-Small-Cell Lung; Cell Membrane; Computer Simulation; Daunorubicin; Diphenylhexatriene; DNA; Drug Resistance; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Lung Neoplasms; Models, Biological; Spectrometry, Fluorescence; Tumor Cells, Cultured; Verapamil; Vincristine

1993
Acute myeloid leukemia presenting as granulocytic sarcoma of the lung.
    American journal of hematology, 1993, Volume: 43, Issue:1

    Topics: Acute Disease; Adult; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Diagnosis, Differential; Etoposide; Humans; Leukemia, Myeloid; Lung Neoplasms; Male

1993
Enhanced response to daunomycin of normal, tumor and metastatic cell lines via drug photoactivation.
    Photochemistry and photobiology, 1993, Volume: 57, Issue:5

    Topics: Animals; Biological Transport; Cell Line; Cell Survival; Darkness; Daunorubicin; Light; Lung Neoplasms; Rats; Rats, Inbred F344; Thyroid Gland; Thyroid Neoplasms; Tumor Cells, Cultured

1993
[Six cases of therapy related leukemia; case reports and review of the literature].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1993, Volume: 20, Issue:10

    Topics: Aclarubicin; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Daunorubicin; Female; Humans; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Lung Neoplasms; Lymphoma; Male; Middle Aged; Neoplasms, Second Primary; Survival Rate

1993
Chemosensitisation and drug accumulation effects of cyclosporin A, PSC-833 and verapamil in human MDR large cell lung cancer cells expressing a 190k membrane protein distinct from P-glycoprotein.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:3

    Topics: Carcinoma, Non-Small-Cell Lung; Cyclosporine; Cyclosporins; Daunorubicin; Humans; Lung Neoplasms; Membrane Proteins; Molecular Weight; Neoplasm Proteins; Tumor Cells, Cultured; Verapamil; Vincristine

1993
Polyaromatic alkaloids from marine invertebrates as cytotoxic compounds and inhibitors of multidrug resistance caused by P-glycoprotein.
    British journal of cancer, 1996, Volume: 74, Issue:5

    Topics: Adenocarcinoma; Alkaloids; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Survival; Colonic Neoplasms; Cricetinae; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Leukemia P388; Lung Neoplasms; Mice; Rhodamine 123; Rhodamines; Tumor Cells, Cultured; Verapamil; Vinblastine

1996
DaunoXome data presented at international cancer meeting.
    Oncology (Williston Park, N.Y.), 1996, Volume: 10, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Daunorubicin; Doxorubicin; Drug Carriers; HIV Infections; Humans; Liposomes; Lung Neoplasms; Sarcoma, Kaposi; Vinblastine

1996
Enhanced sensitivity to 1-beta-D-arabinofuranosylcytosine and topoisomerase II inhibitors in tumor cell lines harboring activated ras oncogenes.
    Cancer research, 1996, Nov-15, Volume: 56, Issue:22

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Colonic Neoplasms; Cytarabine; Daunorubicin; Deoxycytidine; DNA Mutational Analysis; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gemcitabine; Gene Expression Regulation, Neoplastic; Genes, ras; Humans; Lung Neoplasms; Software; Topoisomerase II Inhibitors; Tumor Cells, Cultured

1996
Activation of NF-kappaB by antineoplastic agents. Role of protein kinase C.
    The Journal of biological chemistry, 1997, Jun-06, Volume: 272, Issue:23

    Topics: Adenocarcinoma; Antineoplastic Agents; Binding, Competitive; Cell Nucleus; Cycloheximide; Dactinomycin; Daunorubicin; Dexamethasone; Doxorubicin; Enzyme Inhibitors; Humans; Kinetics; Lung Neoplasms; NF-kappa B; Oligodeoxyribonucleotides; Paclitaxel; Protein Kinase C; Transcription Factors; Tumor Cells, Cultured; Vincristine

1997
Autologous bone marrow purging by in situ IL-2 activation of endogenous killer cells.
    Leukemia, 1997, Volume: 11, Issue:5

    Topics: Bone Marrow Purging; Bone Marrow Transplantation; Breast Neoplasms; Colony-Forming Units Assay; Cytarabine; Cytotoxicity, Immunologic; Daunorubicin; Drug Resistance, Neoplasm; Etoposide; Female; Hematopoietic Stem Cells; HL-60 Cells; Humans; Interleukin-2; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Leukemia; Lung Neoplasms; Lymphocyte Activation; Tissue Donors; Transplantation, Autologous; Transplantation, Homologous; Tumor Cells, Cultured

1997
Expression of the multidrug resistance-associated protein (MRP) and chemoresistance of human non-small-cell lung cancer cells.
    International journal of cancer, 1997, Sep-26, Volume: 73, Issue:1

    Topics: Aged; ATP-Binding Cassette Transporters; Carcinoma, Non-Small-Cell Lung; Daunorubicin; Drug Resistance, Multiple; Female; Humans; Lung Neoplasms; Male; Middle Aged; Multidrug Resistance-Associated Proteins; RNA, Messenger; Tumor Cells, Cultured

1997
Kinetics of anthracycline efflux from multidrug resistance protein-expressing cancer cells compared with P-glycoprotein-expressing cancer cells.
    Molecular pharmacology, 1998, Volume: 53, Issue:1

    Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Carcinoma, Small Cell; Daunorubicin; Doxorubicin; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Lung Neoplasms; Multidrug Resistance-Associated Proteins

1998
Increased sensitivity to gemcitabine of P-gP and MRP overexpressing human non-small cell lung cancer cell lines.
    Advances in experimental medicine and biology, 1998, Volume: 431

    Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Carcinoma, Non-Small-Cell Lung; Daunorubicin; Deoxycytidine; Doxorubicin; Drug Resistance, Multiple; Gemcitabine; Humans; Lung Neoplasms; Multidrug Resistance-Associated Proteins; Tumor Cells, Cultured

1998
Characterization of H+-ATPase-dependent activity of multidrug resistance-associated protein in homoharringtonine-resistant human leukemic K562 cells.
    Leukemia, 1998, Volume: 12, Issue:10

    Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Buthionine Sulfoximine; Cell Survival; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Harringtonines; Homoharringtonine; Humans; K562 Cells; Kinetics; Lung Neoplasms; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Proton-Translocating ATPases; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured

1998
Effect of Tween-80 on cell killing by etoposide in human lung adenocarcinoma cells.
    Cancer chemotherapy and pharmacology, 1999, Volume: 43, Issue:1

    Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Daunorubicin; Drug Resistance, Neoplasm; Drug Synergism; Etoposide; Humans; Lung Neoplasms; Polysorbates; Surface-Active Agents; Tumor Cells, Cultured

1999
A new in vivo method to study P-glycoprotein transport in tumors and the blood-brain barrier.
    Cancer research, 1999, May-15, Volume: 59, Issue:10

    Topics: Animals; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain Chemistry; Calcium Channel Blockers; Carcinoma, Small Cell; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Lung Neoplasms; Male; Metabolic Clearance Rate; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms; Rats; Rats, Nude; Recombinant Fusion Proteins; Tissue Distribution; Tumor Cells, Cultured; Verapamil

1999
Anticancer derivative of butyric acid (Pivalyloxymethyl butyrate) specifically potentiates the cytotoxicity of doxorubicin and daunorubicin through the suppression of microsomal glycosidic activity.
    Molecular pharmacology, 2000, Volume: 58, Issue:1

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Biological Transport; Butyrates; Cell Cycle; Cell Division; Daunorubicin; DNA; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Glycoside Hydrolases; Humans; Lung Neoplasms; Lymphoma; Microsomes; Oligonucleotides, Antisense; Structure-Activity Relationship; Tumor Cells, Cultured

2000
Expression of the major vault protein LRP in human non-small-cell lung cancer cells: activation by short-term exposure to antineoplastic drugs.
    International journal of cancer, 2000, Oct-15, Volume: 88, Issue:2

    Topics: Antineoplastic Agents; Bleomycin; Carcinoma, Non-Small-Cell Lung; Cell Line; Cisplatin; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Etoposide; Fibroblasts; Gene Expression Regulation; Humans; Lung; Lung Neoplasms; Neoplasm Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Vault Ribonucleoprotein Particles; Vinblastine

2000
Paclitaxel sensitization of multidrug-resistant cells to chemotherapy is independent of the cell cycle.
    Cytometry, 2001, Mar-01, Volume: 43, Issue:3

    Topics: Amsacrine; Antineoplastic Agents; Camptothecin; Carcinoma, Small Cell; Cell Cycle; Cell Survival; Chlorambucil; Cisplatin; Daunorubicin; Drug Resistance, Multiple; Epirubicin; Genistein; Humans; Lung Neoplasms; Paclitaxel; Tumor Cells, Cultured; Vinblastine; Vinorelbine

2001
Collateral sensitivity to gemcitabine (2',2'-difluorodeoxycytidine) and cytosine arabinoside of daunorubicin- and VM-26-resistant variants of human small cell lung cancer cell lines.
    Biochemical pharmacology, 2001, Jun-01, Volume: 61, Issue:11

    Topics: Adenosine Triphosphate; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Carcinoma, Small Cell; Cell Survival; Cytarabine; Cytidine Deaminase; Daunorubicin; Deoxycytidine; Deoxycytidine Kinase; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Gemcitabine; Guanosine Triphosphate; Humans; Lung Neoplasms; Nucleoside Deaminases; Teniposide; Thymidine Kinase; Tumor Cells, Cultured; Uridine Triphosphate

2001
Role of ceramide in mediating the inhibition of telomerase activity in A549 human lung adenocarcinoma cells.
    The Journal of biological chemistry, 2001, Jul-06, Volume: 276, Issue:27

    Topics: Adenocarcinoma; Blotting, Western; Cell Membrane; Ceramides; Daunorubicin; Dose-Response Relationship, Drug; Flow Cytometry; G1 Phase; Glucosylceramides; Glucosyltransferases; Humans; Lung Neoplasms; Phosphatidylserines; Poly(ADP-ribose) Polymerases; Resting Phase, Cell Cycle; Sphingomyelin Phosphodiesterase; Telomerase; Time Factors; Transfection; Tumor Cells, Cultured

2001
Kinetics of glutathione and daunorubicin efflux from multidrug resistance protein overexpressing small-cell lung cancer cells.
    European journal of pharmacology, 2001, Jun-01, Volume: 421, Issue:1

    Topics: ATP-Binding Cassette Transporters; Biological Transport; Carcinoma, Small Cell; Cyclic P-Oxides; Daunorubicin; Dose-Response Relationship, Drug; Extracellular Space; Gene Expression Regulation, Neoplastic; Glutathione; Humans; K562 Cells; Kinetics; Lung Neoplasms; Multidrug Resistance-Associated Proteins; Nicotinic Acids; Propionates; Quinolines; Time Factors; Tumor Cells, Cultured; Vinblastine

2001
[Primary pulmonary manifestation of extramedullary acute myelocytic leukemia].
    Pneumologie (Stuttgart, Germany), 2001, Volume: 55, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Blast Crisis; Bronchoalveolar Lavage Fluid; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Middle Aged; Prednisolone; Radiography; Thioguanine; Vincristine

2001
The proline-rich domain of p53 is required for cooperation with anti-neoplastic agents to promote apoptosis of tumor cells.
    Oncogene, 2002, Jan-03, Volume: 21, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Clone Cells; Colchicine; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Daunorubicin; DNA Damage; DNA, Neoplasm; Etoposide; Fluorouracil; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Lung Neoplasms; Models, Biological; Proline; Promoter Regions, Genetic; Protein Structure, Tertiary; Recombinant Fusion Proteins; Structure-Activity Relationship; Tetracycline; Transcription, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2002
[Reversal of multidrug resistance in lung adenocarcinoma-resistant cell line A549/R by mdr1 antisense oligodeoxynucleotides in vitro].
    Zhonghua yi xue za zhi, 2000, Volume: 80, Issue:3

    Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Daunorubicin; DNA; Drug Resistance, Multiple; Fluorescent Dyes; Humans; Lung Neoplasms; Oligodeoxyribonucleotides, Antisense; Rhodamines; RNA, Messenger; Tumor Cells, Cultured

2000
Doxorubicin, radiotherapy, and oesophageal stricture.
    Lancet (London, England), 1975, Sep-20, Volume: 2, Issue:7934

    Topics: Carcinoma, Small Cell; Daunorubicin; Esophageal Stenosis; Female; Humans; Lung Neoplasms; Middle Aged; Radiotherapy

1975
Effect of antitumor agents on sarcoma-180 tumor cells transplanted to liver, kidney, and lung.
    Gan, 1975, Volume: 66, Issue:3

    Topics: Animals; Antineoplastic Agents; Bleomycin; Cyclophosphamide; Dactinomycin; Daunorubicin; Fluorouracil; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Mice; Mitomycins; Neoplasm Transplantation; Sarcoma 180

1975
Sensitivity tests of tumors to cytostatic agents. II. Investigation on human tumors.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1975, Volume: 83, Issue:2

    Topics: Antineoplastic Agents; Autoradiography; Breast Neoplasms; Cell Count; Cell Division; Culture Techniques; Dactinomycin; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Lung Neoplasms; Neoplasms; Nucleic Acids; Ovarian Neoplasms; Procarbazine; Uridine

1975
Binding of anti-tumor immunoglobulins and their daunomycin conjugates to the tumor and its metastase. In vitro and in vivo studies with Lewis lung carcinoma.
    International journal of cancer, 1979, Oct-15, Volume: 24, Issue:4

    Topics: Animals; Antibodies, Neoplasm; Binding Sites, Antibody; Daunorubicin; Fluorescent Antibody Technique; Immunoglobulins; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Transplantation, Isogeneic

1979
[Chemotherapy of uterine chorionepithelioma metastases to the lungs].
    Akusherstvo i ginekologiia, 1979, Issue:12

    Topics: Adult; Antibiotics, Antineoplastic; Choriocarcinoma; Dactinomycin; Daunorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Methotrexate; Middle Aged; Pregnancy; Time Factors; Uterine Neoplasms

1979
Differential distribution of antitumor agents in primary and secondary tumors.
    Cancer treatment reports, 1977, Volume: 61, Issue:7

    Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Carcinoma 256, Walker; Cyclophosphamide; Daunorubicin; Doxorubicin; Female; Hydroxyurea; Lung Neoplasms; Lymphatic Metastasis; Male; Mercaptopurine; Methotrexate; Methylnitrosourea; Mice; Neoplasm Metastasis; Neoplasms, Experimental; Rats; Sarcoma, Experimental

1977
Activity of anthracyclines against an adriamycin (NSC-123127)-resistant subline of P388 leukemia with special emphasis on cinerubin A (NSC-18334).
    Cancer treatment reports, 1976, Volume: 60, Issue:1

    Topics: Animals; Antibiotics, Antineoplastic; Carubicin; Chemical Phenomena; Chemistry; Daunorubicin; Doxorubicin; Drug Resistance; Haplorhini; Leukemia L1210; Leukemia, Experimental; Lung Neoplasms; Male; Melanoma; Mice; Neoplasm Transplantation; Transplantation, Homologous

1976
Antineoplastic activity and pharmacokinetics of adriamycin and daunomycin in tumor bearing mice.
    Oncology, 1977, Volume: 34, Issue:4

    Topics: Animals; Cell Survival; Culture Techniques; Daunorubicin; Doxorubicin; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Neoplasms, Experimental

1977
[Testing of the resistance of human tumours in the short-term test (author's transl)].
    Klinische Wochenschrift, 1975, Jun-15, Volume: 53, Issue:12

    Topics: Antibiotics, Antineoplastic; Dactinomycin; Daunorubicin; Doxorubicin; Drug Resistance; Female; Humans; Lung Neoplasms; Ovarian Neoplasms; Thymidine; Triaziquone; Uridine

1975
[The effect of experimental hepatopathy on the nature of the spontaneous metastasis of Lewis lung carcinoma].
    Voprosy onkologii, 1992, Volume: 38, Issue:7

    Topics: Animals; Carbon Tetrachloride Poisoning; Carcinoma, Squamous Cell; Chemical and Drug Induced Liver Injury; Daunorubicin; Drug Screening Assays, Antitumor; Female; Lipids; Liver; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Vincristine

1992
Energy-dependent processes involved in reduced drug accumulation in multidrug-resistant human lung cancer cell lines without P-glycoprotein expression.
    Cancer research, 1992, Jan-01, Volume: 52, Issue:1

    Topics: Adenosine Triphosphate; Carcinoma, Non-Small-Cell Lung; Cell Membrane Permeability; Daunorubicin; Drug Resistance; Energy Metabolism; Etoposide; Gene Expression Regulation, Neoplastic; Humans; Hydrogen-Ion Concentration; Lung Neoplasms; Nigericin; Phenotype; RNA, Messenger; Tumor Cells, Cultured; Vincristine

1992
Genetic transfer of non-P-glycoprotein-mediated multidrug resistance (MDR) in somatic cell fusion: dissection of a compound MDR phenotype.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Apr-15, Volume: 89, Issue:8

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Non-Small-Cell Lung; Cell Fusion; Cell Line; Cell Survival; Daunorubicin; DNA Topoisomerases, Type II; Drug Resistance; Gene Expression; Humans; Kinetics; Lung Neoplasms; Membrane Glycoproteins; Phenotype; RNA, Messenger; Transfection; Vincristine

1992
Circumvention of doxorubicin resistance in multi-drug resistant human leukaemia and lung cancer cells by the pure antioestrogen ICI 164384.
    European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:6

    Topics: Carcinoma, Small Cell; Cell Division; Cell Line; Daunorubicin; Doxorubicin; Drug Resistance; Estradiol; Estrogen Antagonists; Humans; Leukemia, T-Cell; Lung Neoplasms; Polyunsaturated Alkamides; Tumor Cells, Cultured

1991
Antagonistic effect of aclarubicin on daunorubicin-induced cytotoxicity in human small cell lung cancer cells: relationship to DNA integrity and topoisomerase II.
    Cancer research, 1991, Oct-01, Volume: 51, Issue:19

    Topics: Aclarubicin; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Ehrlich Tumor; Carcinoma, Small Cell; Colony-Forming Units Assay; Daunorubicin; DNA; DNA Damage; DNA Replication; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Antagonism; Humans; In Vitro Techniques; Lung Neoplasms; Mice; Verapamil

1991
Retention of activity by selected anthracyclines in a multidrug resistant human large cell lung carcinoma line without P-glycoprotein hyperexpression.
    British journal of cancer, 1991, Volume: 63, Issue:3

    Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma; Daunorubicin; Drug Resistance; Humans; Lung Neoplasms; Membrane Glycoproteins; Tumor Cells, Cultured; Verapamil

1991
Experimental transplantation models of mouse sarcoma 180 in ICR mice for evaluation of anti-tumor drugs.
    The Journal of veterinary medical science, 1991, Volume: 53, Issue:4

    Topics: Aclarubicin; Animals; Antineoplastic Agents; Daunorubicin; Disease Models, Animal; Doxorubicin; Lung Neoplasms; Male; Mice; Mice, Inbred ICR; Neoplasm Transplantation; Sarcoma 180; Skin Neoplasms; Specific Pathogen-Free Organisms

1991
[Antitumor activities of orally administered 7-con-0-methylnogarol (TUT-7)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1990, Volume: 17, Issue:3 Pt 1

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Colonic Neoplasms; Daunorubicin; Doxorubicin; Humans; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Lung Neoplasms; Menogaril; Mice; Nogalamycin; Rats; Sarcoma, Yoshida

1990
Effective drug-antibody targeting using a novel monoclonal antibody against the proliferative compartment of mammalian squamous carcinomas.
    Cancer immunology, immunotherapy : CII, 1990, Volume: 32, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Carcinoma, Squamous Cell; Cell Division; Daunorubicin; Immunotoxins; Injections, Intravenous; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Neoplasm Transplantation

1990
Multidrug resistance in a human small cell lung cancer cell line selected in adriamycin.
    Cancer research, 1987, May-15, Volume: 47, Issue:10

    Topics: Animals; Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Small Cell; Cell Line; Colchicine; Daunorubicin; Doxorubicin; Drug Resistance; Enzyme-Linked Immunosorbent Assay; Epirubicin; Etoposide; Glycoproteins; Gramicidin; Humans; Immunosorbent Techniques; Isoxazoles; Lung Neoplasms; Menogaril; Mice; Mice, Inbred BALB C; Mitoxantrone; Nogalamycin; Phenotype; Vinblastine; Vincristine

1987
Correlation of multidrug resistance with decreased drug accumulation, altered subcellular drug distribution, and increased P-glycoprotein expression in cultured SW-1573 human lung tumor cells.
    Cancer research, 1989, Jun-01, Volume: 49, Issue:11

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Division; Cell Line; Cell Nucleus; Daunorubicin; Doxorubicin; Drug Resistance; Humans; Lung Neoplasms; Membrane Glycoproteins; Superoxide Dismutase; Tumor Cells, Cultured; Verapamil

1989
In vitro evaluation of the potential of aclarubicin in the treatment of small cell carcinoma of the lung (SCCL).
    British journal of cancer, 1989, Volume: 60, Issue:6

    Topics: Aclarubicin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Proteins; Carcinoma, Small Cell; Daunorubicin; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Humans; In Vitro Techniques; Lung Neoplasms; Membrane Glycoproteins; Mitoxantrone; Tumor Stem Cell Assay

1989
Testing new drugs in untreated small cell lung cancer may prejudice the results of standard treatment: a phase II study of oral idarubicin in extensive disease.
    Cancer treatment reports, 1987, Volume: 71, Issue:12

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Daunorubicin; Drug Evaluation; Humans; Idarubicin; Lung Neoplasms; Middle Aged; Neoplasm Metastasis

1987
Negative phase II trial of menogaril in advanced squamous, adeno- and large cell carcinoma of the lung.
    European journal of cancer & clinical oncology, 1988, Volume: 24, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Daunorubicin; Drug Evaluation; Female; Humans; Lung Neoplasms; Male; Menogaril; Middle Aged; Nogalamycin

1988
No response improvement after sequential chemotherapy for small cell lung cancer.
    European journal of respiratory diseases, 1986, Volume: 68, Issue:4

    Topics: Adult; Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cisplatin; Cyclophosphamide; Daunorubicin; Drug Evaluation; Etoposide; Female; Humans; Lomustine; Lung Neoplasms; Male; Middle Aged; Prednisone; Time Factors; Vincristine

1986
[Cytotoxic action of doxorubicin and daunomycin on human lung cancer cells].
    Antibiotiki i meditsinskaia biotekhnologiia = Antibiotics and medical biotechnology, 1986, Volume: 31, Issue:8

    Topics: Adenocarcinoma; Animals; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Daunorubicin; Doxorubicin; Drug Evaluation, Preclinical; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred CBA; Neoplasm Transplantation

1986
[Targeting of anthracyclines and hepatomas].
    Pathologie-biologie, 1987, Volume: 35, Issue:1

    Topics: Adult; Aged; Animals; Carcinoma, Hepatocellular; Daunorubicin; Drug Combinations; Drug Evaluation; Humans; Liver Neoplasms; Lung Neoplasms; Mice; Mice, Nude; Middle Aged; Serum Albumin

1987
[Establishment of adriamycin-resistant human small-cell lung cancer cells in culture: analysis of the mechanism of resistance and cross-resistance].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:3 Pt 2

    Topics: Carcinoma, Small Cell; Cells, Cultured; Colony-Forming Units Assay; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Humans; Lethal Dose 50; Lung Neoplasms; Mitomycin; Mitomycins; Tumor Stem Cell Assay; Vincristine

1987
Activity of (7) anthracycline related compounds in an doxorubicin sensitive human small cell lung cancer line and its doxorubicin resistant descendant. Activity of doxorubicin, daunorubicin, 4-deoxyrubicin, 4-demethoxydaunorubicin, detorubicin, 4'-epidoxo
    European journal of respiratory diseases. Supplement, 1987, Volume: 149

    Topics: Antibiotics, Antineoplastic; Carcinoma, Small Cell; Daunorubicin; Doxorubicin; Drug Resistance; Humans; Idarubicin; Lung Neoplasms; Mitoxantrone; Naphthacenes; Tumor Stem Cell Assay

1987
Method for the determination of 4-demethoxydaunorubicin, its quinone and hydroquinone metabolites in human plasma and urine by high-performance liquid chromatography.
    Cancer chemotherapy and pharmacology, 1987, Volume: 19, Issue:4

    Topics: Carcinoma, Small Cell; Chromatography, High Pressure Liquid; Daunorubicin; Humans; Hydroquinones; Idarubicin; Lung Neoplasms; Quinones

1987
p-Benzylthiocarbamoyl-aspartyl-daunorubicin-substituted polytrisacryl. A new drug acid-labile arm-carrier conjugate.
    European journal of biochemistry, 1988, Oct-01, Volume: 176, Issue:3

    Topics: Acrylates; Aspartic Acid; Binding Sites; Carcinoma; Cell Survival; Daunorubicin; Hydrogen-Ion Concentration; Lung Neoplasms; Pharmaceutical Vehicles; Thiocarbamates; Tumor Cells, Cultured

1988
Comparative cellular uptake and cytotoxicity of a complex of daunomycin-low density lipoprotein in human squamous lung tumour cell monolayers.
    Biochemical pharmacology, 1988, Oct-15, Volume: 37, Issue:20

    Topics: Carcinoma, Squamous Cell; Cell Survival; Daunorubicin; Humans; Lipoproteins, LDL; Lung Neoplasms; Microscopy, Fluorescence; Tumor Cells, Cultured

1988
In vitro chemosensitivity testing using the multicellular tumor spheroid model.
    Cancer drug delivery, 1987, Volume: 4, Issue:2

    Topics: Antibiotics, Antineoplastic; Cell Survival; Daunorubicin; Doxorubicin; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Microscopy, Fluorescence; Tumor Cells, Cultured

1987
Oral 4-demethoxydaunorubicin (idarubicin) in bronchogenic lung cancer; phase II trial.
    Investigational new drugs, 1986, Volume: 4, Issue:3

    Topics: Administration, Oral; Adult; Aged; Antibiotics, Antineoplastic; Blood; Carcinoma, Bronchogenic; Daunorubicin; Drug Evaluation; Female; Humans; Idarubicin; Lung Neoplasms; Male; Middle Aged

1986
Patterns of anthracycline retention modulation in human tumor cells.
    Cytometry, 1987, Volume: 8, Issue:3

    Topics: Bone Marrow; Breast Neoplasms; Daunorubicin; Doxorubicin; Female; Humans; Leukemia; Lung Neoplasms; Microscopy, Fluorescence; Neoplasms

1987
Phase II trial of oral 4-demethoxydaunorubicin in patients with non-small cell lung cancer.
    American journal of clinical oncology, 1985, Volume: 8, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Daunorubicin; Drug Evaluation; Female; Humans; Idarubicin; Leukopenia; Lung Neoplasms; Male; Middle Aged

1985
Detorubicin--an active anthracycline in untreated metastatic melanoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1985, Volume: 3, Issue:11

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Daunorubicin; Drug Evaluation; Electrocardiography; Female; Heart; Heart Diseases; Humans; Leukopenia; Lung Neoplasms; Lymphatic Metastasis; Male; Melanoma; Middle Aged; Myocardial Contraction; Skin Neoplasms; Stroke Volume; Thrombocytopenia

1985
[Treatment of isolated metastases from choriocarcinoma of the uterus to the lung].
    Voprosy onkologii, 1974, Volume: 20, Issue:10

    Topics: Adult; Antineoplastic Agents; Choriocarcinoma; Colchicine; Dactinomycin; Daunorubicin; Female; Flavonoids; Humans; Lung Neoplasms; Melphalan; Mercaptopurine; Methotrexate; Middle Aged; Mitomycins; Neoplasm Metastasis; Olivomycins; Pneumonectomy; Pregnancy; Uterine Neoplasms; Vinblastine

1974
[Clinical trial of daunomycin in gynecological oncology].
    Annali di ostetricia, ginecologia, medicina perinatale, 1969, Volume: 91, Issue:11

    Topics: Carcinoma, Squamous Cell; Daunorubicin; Female; Genital Neoplasms, Female; Humans; L-Lactate Dehydrogenase; Lung Neoplasms; Myosarcoma; Neoplasm Metastasis; Phosphoric Monoester Hydrolases; Transaminases; Uterine Cervical Neoplasms

1969
[Research on optimal dosage schemes in clinical experimentation with antineoplastic agents].
    Bollettino chimico farmaceutico, 1972, Volume: 111, Issue:2

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Combinations; Glycosides; Humans; Leukemia, Myeloid, Acute; Lung Neoplasms; Naphthacenes; Neoplasms

1972
[Trial of chemotherapy with a new antimitotic derivative].
    La Nouvelle presse medicale, 1973, Mar-03, Volume: 2, Issue:9

    Topics: Antibiotics, Antineoplastic; Carcinoma; Daunorubicin; Fibrosarcoma; Humans; Hydrazones; Kidney Neoplasms; Lung Neoplasms; Neoplasm Metastasis

1973
Renal tumors and other lesions in rats following a single intravenous injection of daunomycin.
    Cancer research, 1972, Volume: 32, Issue:5

    Topics: Adenocarcinoma; Animals; Carcinogens; Daunorubicin; Female; Glomerulonephritis; Hyperparathyroidism, Secondary; Kidney Failure, Chronic; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Neoplasms, Experimental; Osteosclerosis; Rats; Skin Neoplasms; Sternum; Urogenital Neoplasms

1972
Preliminary clinical screening with daunorubicin in lung cancer.
    European journal of cancer, 1970, Volume: 6, Issue:2

    Topics: Adenocarcinoma; Aged; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Daunorubicin; Female; Humans; Lung Neoplasms; Male; Middle Aged

1970