daunorubicin has been researched along with Granulocytic Leukemia in 454 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 123 (27.09) | 18.7374 |
| 1990's | 189 (41.63) | 18.2507 |
| 2000's | 122 (26.87) | 29.6817 |
| 2010's | 20 (4.41) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bhatt, AN; Kalra, N; Kumari, N; Rai, Y; Yadav, P | 1 |
| Becker, PS; Chiarella, MT; Estey, EH; Hendrie, PC; Louie, AC; McDaniel, EN; Medeiros, BC; Orlowski, KF; Othus, M; Percival, MM; Scott, BL; Walter, RB | 1 |
| Stone, RM | 1 |
| Cao, X; Cen, J; Chen, Z; Gu, W; Li, M; Liu, Y; Xiang, L; Xie, X; Zhen, X | 1 |
| Altman, J; Czerniak, C; Greenberg, D; Koslosky, M; Mehta, J; Pantiru, M; Pi, J; Trifilio, S; Zhou, Z | 1 |
| Boddy, N; Burrows, F; Pallis, M; Russell, N; Seedhouse, C; Whittall, A | 1 |
| Ghoneum, A; Gimzewski, J; Sharma, S | 1 |
| Burnett, AK; Hills, RK; Russell, NH | 1 |
| Campana, D; Crews, KR; Downing, JR; Gandhi, VV; Pounds, S; Pui, CH; Raimondi, SC; Razzouk, BI; Ribeiro, RC; Rubnitz, JE; Yang, S | 1 |
| de Bont, ES; Kamps, WA; Koetse, HA; Rings, EH; Stellaard, F; Tissing, WJ; van Vliet, MJ | 1 |
| Baubion, N; Buzyn, A; Decaudin, D; Delarue, R; Fourquet, A; Ghez, D; Hermine, O; Messas, E; Rubio, MT; Suarez, F; Varet, B; Willems, L | 1 |
| Amadori, S; Baila, L; de Witte, T; Di Raimondo, F; Fazi, P; Ferrara, F; Labar, B; Liso, V; Mandelli, F; Marie, JP; Marmont, F; Meloni, G; Muus, P; Petti, MC; Stasi, R; Suciu, S; Thomas, X; Vignetti, M; Willemze, R; Zittoun, R | 1 |
| Rowe, JM | 1 |
| Prenkert, M; Strid, H; Tidefelt, U; Uggla, B | 1 |
| Ashcroft, J; Moreton, P; Parrish, C | 1 |
| Gerhard, B; Harasym, TO; Hogge, DE; Kim, HP; Mayer, LD | 1 |
| Bose, JR; Brenet, F; Curcio, TJ; Feldman, EJ; Gergis, US; Ippoliti, CM; Mayer, SA; Moh, M; Morawa, E; Ritchie, EK; Roboz, GJ; Scandura, JM; Villegas, L | 1 |
| Apfelbaum, SM; Burbage, M; Kircher, S; Kirsch, K; Lofwall, M; Passik, S; Zacny, J | 1 |
| Chen, Y; Feng, L; Han, W; Jin, H; Jin, W; Li, D; Pan, H; Pan, Q; Sun, J; Wang, K; Wang, X | 1 |
| Atenafu, EG; Brandwein, JM; Gupta, V; Minden, MD; Murray, C; Nixon, S; Saini, L; Schimmer, AD; Schuh, AC; Yee, KW | 1 |
| Alonzo, TA; Arceci, RJ; Barnard, D; Gamis, AS; Gerbing, RB; Hathaway, L; Hilden, JM; Loew, TW; Ravindranath, Y; Smith, FO; Sorrell, AD; Taub, JW; Woods, WG | 1 |
| Atkinson, HD; Colovic, M; Colovic, N; Jankovic, G; Kraguljac, N; Radojkovic, M; Stanisavljevic, D; Suvajdzic, N; Tomin, D; Vidovic, A | 1 |
| Chi, M; Estey, E; Lin, A; McQuary, A; Othus, M | 1 |
| Brunsvik, A; Bruserud, Ø; Degnes, KF; Døskeland, SO; Gausdal, G; Herfindal, L; Myhren, LE; Nygaard, G; Selheim, F; Sletta, H; Teigen, K; Zahlsen, K | 1 |
| Beckstrøm, KJ; Bettaïeb, A; Laurent, G; Lautier, D; Lehne, G; Maestre, N; Plo, I | 1 |
| Wheatley, K | 1 |
| Handa, H; Isozumi, K; Komatsumoto, S; Motohashi, S; Nara, M | 1 |
| Belleri, M; Presta, M; Ribatti, D; Vacca, A | 1 |
| Baccarani, M; Isidori, A; Malagola, M; Martinelli, G; Piccaluga, PP; Rondoni, M; Tura, S; Visani, G | 1 |
| Baer, M; Becknell, B; Bloomfield, CD; Caligiuri, MA; Crawford, J; Dodge, RK; Farag, SS; Fehniger, TA; George, SL; Larson, RA; Lee, EJ; Schiffer, CA; Silverman, LR | 1 |
| Chorvath, B; Duraj, J; Hunakova, L; Jakubikova, J; Sedlak, J | 1 |
| Anderson, JE; Appelbaum, FR; Balcerzak, SP; Chen, IM; Head, D; Johnson, DB; Kopecky, KJ; Luthardt, FW; Norwood, TH; O'Donnell, MR; Willman, CL | 1 |
| Arthur, DC; Bloomfield, CD; Byrd, JC; Carroll, AJ; Davey, FR; Dodge, RK; Edwards, CG; Feldman, EJ; Koduru, PR; Larson, RA; Mayer, RJ; Moore, JO; Mrózek, K; Patil, SR; Pettenati, MJ; Rao, KW; Schiffer, CA; Stone, RM; Watson, MS | 1 |
| Aledo, A; Alonzo, TA; Buxton, AB; Kobrinsky, NL; Lange, BJ; Woods, WG | 1 |
| Alonzo, TA; Arceci, RJ; Bernstein, ID; Gerbing, RB; Lange, BJ; Loken, MR; Sievers, EL; Smith, FO; Woods, WG | 1 |
| Appelbaum, FR; Banker, DE; Li, HY; Willman, CL; Zager, RA | 1 |
| Asai, O; Dobashi, N; Kaito, K; Kasama, K; Kobayashi, M; Ogasawara, Y; Ohtsubo, H; Okawa, Y; Saito, T; Sekiguchi, N; Sugiyama, K; Takei, Y; Usui, N; Yahagi, Y; Yamaguchi, Y; Yano, S | 1 |
| Gruber, A; Knaust, E; Peterson, C; Porwit-MacDonald, A; Xu, D | 2 |
| Björkholm, M; Brinch, L; Evensen, S; Gruber, A; Gustavsson, B; Hedenus, M; Juliusson, G; Liliemark, J; Löfvenberg, E; Nesthus, I; Paul, C; Simonsson, B; Sjo, M; Stenke, L; Tangen, JM; Tidefelt, U; Udén, AM | 1 |
| Aoki, Y; Cioca, DP; Kiyosawa, K | 1 |
| Estey, EH; Thall, PF | 1 |
| Ali, R; Kimya, Y; Ozan, U; Ozçelik, T; Ozkalemkaş, F; Ozkocaman, V; Tunali, A | 1 |
| Choi, CH; Kang, G; Min, YD | 1 |
| Aulitzky, W; Bodenstein, H; Ehninger, G; Gramatzki, M; Helm, G; Link, H; Pascheberg, U; Repp, R; Schaekel, U; Sonnen, R; Soucek, S; Thiede, C; Wandt, H | 1 |
| Burnett, AK; Chang, J; Chopra, R; Ewing, JC; Kell, WJ; Morgenstern, GR; Robertson, JD; Ryder, D; Scarffe, JH | 1 |
| Allen, SL; Archer, KJ; Baldus, CD; Bloomfield, CD; Caligiuri, MA; Carroll, AJ; de la Chapelle, A; Kolitz, JE; Larson, RA; Marcucci, G; Moore, JO; Powell, BL; Ruppert, AS; Tanner, SM; Vardiman, JW; Whitman, SP | 1 |
| Davis, J; Estey, E; Kantarjian, H; Koller, C; O'Brien, S; Shen, Y; Thomas, MB; Yang, Y | 1 |
| Baker, RJ; Foroni, L; Ganeshaguru, K; Jones, DT; Mehta, AB; Mitchell, WA; Prentice, HG; Wickremasinghe, RG | 1 |
| Bernabei, P; Biscardi, M; Caporale, R; Ciolli, S; Grossi, A; Leoni, F; Pagliai, G; Santini, V | 1 |
| Boos, J; Creutzig, U; Hempel, G; Reinhardt, D | 1 |
| Bernell, P; Björkholm, M; Celsing, F; Dahl, IM; Dybedal, I; Gahrton, G; Hast, R; Hellström-Lindberg, E; Lerner, R; Lindberg, G; Linder, O; Löfvenberg, E; Nilsson-Ehle, H; Oberg, G; Ohm, L; Paul, C; Samuelsson, J; Tangen, JM; Tidefelt, U; Turesson, I; Wahlin, A; Wallvik, J; Winquist, I | 1 |
| Okamoto, Y; Pui, CH; Razzouk, BI; Ribeiro, RC; Shenep, JL; Srivastava, DK | 1 |
| DUBOST, M; GANTER, P; MARAL, R; NINET, L; PINNERT, S; PREUDHOMME, J; WERNER, GH | 1 |
| Depil, S; Quesnel, B; Saudemont, A; Vereecque, R | 1 |
| Brien, B; Chang, H; Minden, MD; Patterson, B; Salma, F; Yi, QL | 1 |
| Damon, L; Demirer, T; Derigs, G; Ferrante, P; Kröger, N; Rosti, G; Wandt, H; Zander, AR | 1 |
| Graf, M; Hecht, K; Nuessler, V; Pelka-Fleischer, R; Pfister, K; Reif, S; Schmetzer, H | 1 |
| Júźwiak, Z; Krykowski, E; Marczak, A; Robak, T; Wrzesień-Kuś, A | 1 |
| Alonzo, TA; Aplenc, R; Arndt, C; Barnard, D; Dinndorf, P; Feig, S; Feusner, J; Gerbing, R; Lange, BJ; Seibel, N; Smith, FO; Weiman, M | 1 |
| Grazide, S; Jaffrézou, JP; Laurent, G; Lerouge, S; Terrisse, AD | 1 |
| Baer, MR; Bloomfield, CD; George, SL; Kolitz, JE; Larson, RA; Lee, EJ | 1 |
| Haferlach, T; Hiddemann, W; Kern, W; Schnittger, S; Schoch, C; Voskova, D | 1 |
| Gotoh, A; Nakajima, A; Ohyashiki, JH; Ohyashiki, K; Sashida, G; Shin-Ya, K; Sumi, M; Tauchi, T | 1 |
| Blazek, B; Cerná, Z; Gajdos, P; Hak, J; Hrstková, H; Hrusák, O; Jabali, Y; Kopecná, L; Michalová, K; Procházková, D; Ptoszková, H; Sedlácek, P; Smísek, P; Starý, J; Timr, P; Tousovská, K; Vávra, V | 1 |
| Abrahams, L; du Toit, C; McDonald, A; Novitzky, N; Thomas, V | 1 |
| Balleari, E; Ballerini, F; Balocco, M; Canepa, L; Clavio, M; Garrone, A; Gobbi, M; Michelis, GL; Miglino, M; Pierri, I; Venturino, C | 1 |
| Abdel-Latif, ME; Ariffin, H; Ariffin, WA; Chan, LL; Lin, HP | 1 |
| Allen, SL; Bloomfield, CD; Caligiuri, MA; Dodge, RK; George, SL; Hoke, E; Hurd, DD; Kolitz, JE; Larson, RA; Moore, JO; Powell, BL; Shea, TC; Vardiman, JW; Velez-Garcia, E | 1 |
| Baer, MR; Block, AW; Bloomfield, CD; Carroll, AJ; Farag, SS; Koduru, PR; Kolitz, JE; Larson, RA; Mayer, RJ; Moore, JO; Mrózek, K; Pettenati, MJ; Powell, BL; Ruppert, AS; Schiffer, CA; Stamberg, J; Stone, RM; Vardiman, JW | 1 |
| Benderra, Z; Chaoui, D; Faussat, AM; Legrand, O; Marie, JP; Perrot, JY; Sayada, L | 1 |
| Kalaycio, M | 1 |
| Cornely, O; Neurohr, K; Reiser, M; Schinköthe, T; Staib, P; Staltmeier, E | 1 |
| Brandwein, J; Chun, K; Gupta, V; Minden, M; Schuh, A; Wells, R; Yi, QL | 1 |
| Fonatsch, C; Gaiger, A; Jäger, U; Kainz, B; Schwarzinger, I; Sperr, WR | 1 |
| Bloomfield, CD; Carroll, AJ; Edwards, CG; Kolitz, JE; Larson, RA; Maharry, K; Marcucci, G; Mayer, RJ; Moore, JO; Mrózek, K; Pettenati, MJ; Powell, BL; Ruppert, AS; Schiffer, CA; Sterling, LJ; Vardiman, JW | 1 |
| Lemez, P; Urbánek, V | 1 |
| Brychtova, Y; Buchtova, I; Doubek, M; Mayer, J; Palasek, I | 1 |
| Danilatou, V; Kalmanti, M; Mantadakis, E; Papadhimitriou, S; Paterakis, G; Stiakaki, E | 1 |
| de Graaf, SS; Gibson, BE; Hann, IM; Hills, RK; O'Marcaigh, A; Rao, A; Stiller, C; Webb, DK; Wheatley, K | 1 |
| Belloc, F; Lacombe, F; Pigneux, A; Praloran, V; Tabrizi, R; Vial, JP | 1 |
| Aung, L; Kirk, RC; Liang, S; Quah, TC; Tan, RM; Yeoh, AE | 1 |
| Braess, J; Haferlach, T; Holdenrieder, S; Mueller, S; Nagel, D; Schalhorn, A; Seidel, D; Stieber, P | 1 |
| Brandalise, SR; Matsuda, EI; Nowill, AE; Oliveira, SN; Rodrigues, PC; Viana, MB; Yunes, JA | 1 |
| Creutzig, U; Dworzak, M; Graf, N; Hermann, J; Lehrnbecher, T; Niemeyer, CM; Reinhardt, D; Reiter, A; Ritter, J; Stary, J; Zimmermann, M | 1 |
| Baer, MR; Bernacki, RJ; Brooks, TA; Bundy, BN; Ford, LA; Minderman, H; O'Loughlin, KL; Priebe, W; Vredenburg, MR | 1 |
| Asai, O; Dobashi, N; Osawa, H; Saito, T; Sugiyama, K; Takei, Y; Usui, N; Yahagi, Y; Yamaguchi, Y; Yano, S | 1 |
| Arnaud, P; Botton, Sd; Bourhis, JH; Castaigne, S; Cordonnier, C; Corront, B; de Revel, T; Dombret, H; Elhamri, M; Fenaux, P; Gardin, C; Le, QH; Michallet, M; Pautas, C; Preudhomme, C; Quesnel, B; Raffoux, E; Reman, O; Terré, C; Thomas, X | 1 |
| Bordessoule, D; Bourhis, JH; Castaigne, S; Contentin, N; de Botton, S; de Revel, T; Dombret, H; Fagot, T; Fenaux, P; Gardin, C; Michallet, M; Pautas, C; Preudhomme, C; Raffoux, E; Reman, O; Terre, C; Thomas, X; Turlure, P | 1 |
| Ainoon, O; Cheong, SK; Fazlina, N; Hamidah, H; Hamidah, NH; Jamal, R; Maha, A; Zarina, AL; Zulkifli, SZ | 1 |
| Haferlach, C; Hiddemann, W; Schnittger, S; Weisser, M | 1 |
| Amadori, S; Buccisano, F; Consalvo, MI; De Fabritiis, P; Del Poeta, G; Del Principe, MI; Fraboni, D; Maurillo, L; Mazzone, C; Neri, B; Ottaviani, L; Panetta, P; Sarlo, C; Spagnoli, A; Tamburini, A; Venditti, A | 1 |
| Höglund, M; Nahi, H; Paul, C; Sirsjö, A; Tidefelt, U; Tina, E; Uggla, B | 1 |
| Freijs, A; Jonsson, N; Karlsson, MO; Kristensen, J; Larsson, R; Lindhagen, E; Nygren, P; Quartino, A | 1 |
| Cogburn, J; Cualing, H; Khalil, F; Miles, L | 1 |
| Buck, SA; Chen, Q; Diakiw, AE; Dombkowski, AA; Ge, Y; LaFiura, KM; Matherly, LH; Payton, SG; Salagrama, S; Taub, JW | 1 |
| Becton, D; Chang, MN; Dahl, GV; Massey, GV; O'Brien, MM; Raimondi, SC; Ravindranath, Y; Stine, KC; Taub, JW | 1 |
| Jin, J; Jones, AT; Pastrello, D; Penning, NA | 1 |
| Grebe, G; Lira, P | 1 |
| Spiers, AS | 1 |
| Grianti, C; Izzi, T; Moretti, L; Muretto, P | 1 |
| Büchner, T; Hiddemann, W; Kamanabroo, D; Schulte, H; Urbanitz, D; van de Loo, J | 1 |
| Andreeff, M; Arlin, Z; Büchner, T; Clarkson, BD; Hiddemann, W; Wörmann, B | 1 |
| Hossfeld, DK; Kubaschinski, G; Nowrousian, MR; Schaefer, UW; Schmidt, CG | 1 |
| Dantas, M; Drebing, C; Glode, LM; Koeppler, H; Robinson, WA; Thomas, MR | 1 |
| Turnbull, AL; Watkins, SM; Williams, JR | 1 |
| Killmann, SA; Nielsen, HR | 1 |
| Kato, Y; Kawashima, K; Ohno, R; Yamada, K | 1 |
| Fontebuoni, A; Izzi, T; Lucarelli, G; Talevi, N | 1 |
| Cervantes, F; Grañena, A; Montserrat, E; Ribera, JM; Rozman, C | 1 |
| Baccarani, M; Ricci, P; Santucci, MA; Tura, S | 1 |
| Cavalli, F; Coleman, M; Glidewell, O; Holland, JF; Kostinas, JE; Pajak, TF; Rai, KR; Silver, RT | 1 |
| Adamson, JW; Arlin, ZA; Clarkson, BD; Fialkow, PJ; Kempin, SJ; Najfeld, V; Singer, JW | 1 |
| Bloomfield, CD; Peterson, BA | 1 |
| Loth, H; Seeber, S | 1 |
| Bloomfield, CD; Kennedy, BJ; Peterson, BA; Theologides, A | 1 |
| Kondrat'eva, NA; Mazurok, AA; Orel, VG; Vygovskaia, IaI | 1 |
| Dabich, L | 1 |
| Stuart, J | 1 |
| Chow, S; Hedley, DW; Robb, D; Xie, XY | 1 |
| Cherepanova, VV; Gliasova, GA; Isaev, VG; Kaporskaia, TS; Kulikov, SM; Medvedeva, NV; Parovichnikova, EN; Rekhtman, GB; Savchenko, VG; Tikhonova, LIu | 1 |
| Gollapudi, S; Gupta, S; Patel, K; Singh, H | 1 |
| Jehn, U | 1 |
| Curtis, JE; McCulloch, EA; Minden, MD; Minkin, S | 1 |
| Feldmann, L; Guerci, A; Guerci, O; Marchal, S; Merlin, JL; Missoum, N; Rose, C; Witz, F | 1 |
| Davison, G; Jacobs, P; Kelly, S; McLellan, G; Pillay, Y | 1 |
| Löwenberg, B; Nooter, K; Sonneveld, P; te Boekhorst, PA; van Kapel, J | 1 |
| Behm, FG; Boyett, JM; Hancock, ML; Krance, RA; Mahmoud, HH; Pui, CH; Raimondi, SC; Relling, MV; Ribeiro, RC; Sandlund, JT | 1 |
| Creutzig, U; Harbott, J; Löffler, H; Ludwig, WD; Riehm, H; Ritter, J; Schellong, G; Sperling, C; Zimmermann, M | 1 |
| Efferth, T; Fabry, U; Glatte, P; Osieka, R | 1 |
| Andersen, JW; Bennett, JM; Cassileth, PA; Hayes, FA; Mazza, JJ; Oette, D; Paietta, E; Rowe, JM; Stadtmauer, EA; Wiernik, PH | 1 |
| Aster, JC; Inhorn, RC; Roach, SA; Slapak, CA; Soiffer, R; Stone, RM; Tantravahi, R | 1 |
| Lee, JW; Sather, HN | 1 |
| Asou, N; Fujimoto, K; Hiraoka, A; Kobayashi, T; Kuriyama, K; Ohno, R; Saito, H; Tanimoto, M; Teshima, H; Yoshida, M | 1 |
| Clausen, N; Ellegaard, J; Hokland, P; Langkjer, ST; Nørgaard, JM; Palshof, T | 1 |
| Jedlicková, A; Jelínek, J; Lemez, P; Lukásová, M; Palecek, A; Sajdová, J; Vítek, A; Vorlová, Z | 1 |
| Lemez, P | 1 |
| Bailly, JD; Bordier, C; Demur, C; Gassar, G; Jaffrézou, JP; Laurent, G; Muller, C | 1 |
| Champlin, R; Gajewski, J; Ho, W; Lee, M; Schiller, G; Territo, M | 1 |
| Cianfriglia, M; Eisterer, W; Gotwald, M; Hilbe, W; Hofmann, J; Ludescher, C; Thaler, J; Zabernigg, A | 1 |
| Cassileth, PA; Friedenberg, WR; Hocking, WG; Marx, JJ; Mazza, JJ; Mercier, RJ; Miller, HJ; Raich, PC; Reding, DJ; Schloesser, LL | 1 |
| Bhalla, K; Bullock, G; Huang, Y; Ibrado, AM; Mahoney, ME; Ponnathpur, V; Ray, S; Self, S; Tang, C; Tourkina, E | 1 |
| Götzl, M; Gsur, A; Kyrle, PA; Lechner, K; Pirker, R; Zöchbauer, S | 1 |
| Boutagy, J; Galettis, P; Ma, DD | 1 |
| Nakamura, T; Ueda, T; Urasaki, Y | 1 |
| Braquet, P; Coulomb, H; Faussat-Suberville, AM; Marie, JP; Principe, P | 1 |
| al-Sabah, A; Baines, P; Burnett, A; Hoy, T; Limaye, M; Padua, RA; Whittaker, J | 1 |
| Conley, NS; Doughney, KB; Durkin, WJ; Favis, GR; Siddiqui, T; Smith, AE; Weiss, R | 1 |
| Cherepanova, VV; Isaev, VG; Kaporskaia, TS; Kliasova, GA; Kulikov, SM; Medvedeva, NV; Parovichnikova, EN; Rekhtman, GB; Savchenko, VG; Tikhonova, LIu | 1 |
| Fukushima, T; Kawai, Y; Nakamura, T; Ueda, T; Urasaki, Y; Yoshida, A | 1 |
| Andreeff, M; Godfrey, L; Hegewisch-Becker, S; Maslak, P | 1 |
| Chatterjee, R; Franklin, IM; Goldstone, AH; Hutchinson, RM; Kelsey, SM; Linch, DC; McMillan, AK; Milligan, DW; Newland, AC; Salooja, N | 1 |
| Berman, E; McBride, M; Tong, W | 1 |
| Belloc, F; Boiron, JM; Cony-Makhoul, P; Dubosc-Marchenay, N; Dumain, P; Fabères, C; Lacombe, F; Marit, G; Montastruc, M; Puntous, M | 1 |
| Berg, DT; Davis, RB; Frei, E; Mayer, RJ; McIntyre, OR; Moore, JO; Omura, GA; Powell, BL; Schiffer, CA; Schulman, P | 1 |
| Faussat-Suberville, AM; Marie, JP; Zhou, D; Zittoun, R | 1 |
| Baier, M; Dalton, W; Dorr, R; Futscher, B; Greer, J; Hutter, J; List, AF; Salmon, S; Spier, C; Wolff, S | 1 |
| Boezeman, J; de Witte, T; Haanen, C; Linssen, P; Minderman, H; van der Lely, N; Wessels, J | 1 |
| Damon, LE; Linker, CA; Ries, CA; Rugo, HS | 1 |
| Amaki, I; Kawashima, K; Kimura, K; Maekawa, T; Masaoka, T; Nagura, E; Ohta, K; Takaku, F; Uchino, H; Yamada, K | 1 |
| Akashi, K; Eto, T; Harada, M; Harada, N; Inaba, S; Niho, Y; Okamura, T; Takamatsu, Y; Teshima, T | 1 |
| Perilov, AA; Poddubnaia, IV | 1 |
| Almqvist, A; Hallman, H; Honkanen, T; Järvenpää, E; Järventie, G; Koistinen, P; Koivunen, E; Lahtinen, R; Lehtinen, M; Ruutu, T | 1 |
| Chan, JC; Chan, JK; Lam, SY; Wong, KF | 1 |
| Fujimura, T; Iwabuchi, A; Kawakubo, K; Kodama, A; Ohyashiki, JH; Ohyashiki, K; Toyama, K | 1 |
| Basu, SK; Mukhopadhyay, A; Mukhopadhyay, B | 1 |
| Darbyshire, PJ; Mann, JR; Sartori, PC; Stevens, MC; Taylor, MH | 1 |
| Barcos, M; Gartside, P; Kukla, C; Lampkin, B; Lykins, J; Preisler, H; Raza, A; Sheikh, Y; White, M; Yousuf, N | 1 |
| Andresen, SW; Bergfeld, WF; Thorisdottir, K; Tomecki, KJ | 1 |
| Del Poeta, G; Delaroche, I; Masi, M; Nicoletti, B; Papa, G; Stasi, R; Tedeschi, B; Tribalto, M; Venditti, A; Vernole, P | 1 |
| Asou, N; Hiraoka, A; Imai, K; Kobayashi, T; Kodera, Y; Ohno, R; Takahashi, I; Tanimoto, M; Tomonaga, M; Tsubaki, K | 1 |
| Asou, N; Emi, N; Hiraoka, A; Jinnai, I; Kageyama, S; Kanamaru, A; Kobayashi, T; Kuriyama, K; Matsuoka, A; Minami, S; Minato, K; Miyawaki, S; Murakami, H; Naoe, T; Oh, H; Ohmoto, E; Ohno, R; Saito, K; Sakamaki, H; Takahashi, I; Tanimoto, M; Tomonaga, M; Tsubaki, K; Yamada, O; Yoshida, M | 1 |
| Dann, EJ; Gillis, S; Rund, D | 1 |
| Grande, M | 1 |
| Braess, J; Hiddemann, W; Kaufmann, CC; Kern, W; Kühn, S; Rührs, H; Schleyer, E; Sträubel, G; Unterhalt, M | 1 |
| Wiernik, PH | 3 |
| Camitta, B; Carroll, A; Chang, MN; Graham-Pole, J; Inoue, S; Krischer, J; Ravindranath, Y; Steuber, CP; Weinstein, HJ; Yeager, AM | 1 |
| Bishop, JF; Bradstock, K; Cobcroft, R; Enno, A; Fox, R; Garson, OM; Gillett, A; Herrmann, R; Joshua, D; Juneja, S; Lowenthal, RM; Matthews, JP; Page, F; Szer, J; Van Der Weyden, M; Wolf, MM; Young, GA | 1 |
| Broxterman, HJ; Eekman, CA; Feller, N; Lankelma, J; Löwenberg, B; Ossenkoppele, GJ; Pinedo, HM; Schoester, M; Schuurhuis, GJ; Sonneveld, P; Währer, DC | 1 |
| Arthur, DC; Barnard, DR; Buckley, JD; DeSwarte, J; Dusenbery, K; Gold, S; Kalousek, D; Kobrinsky, N; Lange, BJ; Lee, JW; Neudorf, S; Sanders, J; Woods, WG | 1 |
| Brandt, ML; Dorfman, SR; Dreyer, ZE; Murray, JC | 1 |
| Barnett, MJ; Philips, GL; Shepherd, JD | 1 |
| Clausen, N; Hokland, P; Langkjer, ST; Nørgaard, JM; Palshof, T; Pedersen, B | 1 |
| Huismans, DR; Klumper, E; Loonen, AH; Ossenkoppele, GJ; Pieters, R; Rottier, A; Veerman, AJ; Westra, G | 1 |
| Chong, SY; Hahn, JS; Ko, YW; Lee, JW; Lee, S; Min, YH | 1 |
| Estey, EH; Freireich, EJ; Ghaddar, HM; Kantarjian, HM; Keating, MJ; Pierce, S | 1 |
| Feldmann, L; Guerci, A; Guerci, O; Marchal, S; Merlin, JL; Missoum, N | 1 |
| Gray, RG; Rees, JK; Wheatley, K | 1 |
| Appelbaum, FR; Bensinger, WI; Buckner, CD; Chauncey, T; Demirer, T; Fefer, A; Lilleby, K; Petersen, FB; Rowley, S; Sanders, J; Storb, R | 1 |
| Dyson, PG; Juttner, CA; Roberts, MM; To, LB; Willson, K | 1 |
| Belotti, D; Corneo, G; Maffè, PF; Pogliani, EM; Rivolta, GF | 1 |
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| Chim, CS; Kwong, YL | 1 |
| Archimbaud, E; Auzanneau, G; Cony-Makhoul, P; Cordonnier, C; Dombret, H; Dreyfus, F; Fenaux, P; Ffrench, M; Leblond, V; Marie, JP; Thomas, X; Tilly, H; Troussard, X | 1 |
| Attal, M; Blaise, D; Broustet, A; Cony-Makhoul, P; Corront, B; Faberes, C; Gastaut, JA; Hollard, D; Huguet, F; Laurent, G; Maraninchi, D; Marit, G; Michallet, M; Molina, L; Pris, J; Reiffers, J; Stoppa, AM | 1 |
| Appelbaum, FR; Banker, DE; Groudine, M; Norwood, T | 1 |
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| Chen, H; Choi, CH; Hedley, DW; Ling, V; Minden, MD; Xie, SX | 1 |
| Boesen, AM; de Nully Brown, P; Grønbaek, K; Hansen, OP; Hippe, E; Hoffmann, T; Jensen, MK; Pedersen-Bjergaard, J; Storm, HH; Thorling, K | 1 |
| Honma, Y; Kasukabe, T; Rephaeli, A | 1 |
| Burnett, AK; Goldstone, AH; Gray, RG; Hann, IM; Rees, JK; Stevens, RF; Wheatley, K | 1 |
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| Auf der Landwehr, U; Büchner, T; Hiddemann, W; Jahns-Streubel, G; Reuter, C; Schleyer, E; Unterhalt, M; Wörmann, B | 1 |
| Becton, DL; Buck, SA; Huang, X; Ravindranath, Y; Stout, ML; Taub, JW; Vega, RA | 1 |
| Ashman, LK; Sincock, PM | 1 |
| Bradley, SJ; Gosriwitana, I; Hider, RC; Porter, JB; Srichairatanakool, S | 1 |
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| Abgrall, JF; Audhuy, B; Briere, J; Cahn, JY; Caillot, D; Casassus, P; Delain, M; Desablens, B; Francois, S; Guilhot, F; Guyotat, D; Harousseau, JL; Herve, P; Hurteloup, P; Lamy, T; Lioure, B; Milpied, N; Pignon, B; Tellier, Z; Witz, F | 1 |
| Borg, AG; Burgess, R; Fisher, A; Grey, M; Wood, P; Yin, JA | 1 |
| Bartolucci, A; Berman, E; Vélez-Gárcia, E; Vogler, R; Whaley, FS; Wiernik, P | 1 |
| de Nully Brown, P; Geisler, CH; Jurlander, J; Pedersen-Bjergaard, J; Victor, MA | 1 |
| Akashi, K; Eto, T; Fujisaki, T; Gondo, H; Harada, M; Harada, N; Hayashi, S; Hirota, Y; Kinukawa, N; Makino, S; Matsuishi, E; Miyamoto, T; Mizuno, S; Murakawa, M; Nagafuji, K; Niho, Y; Ohno, Y; Okamura, T; Shibuya, T; Takamatsu, Y; Takenaka, K; Taniguchi, S; Tanimoto, K; Teshima, T; Yamasaki, K | 1 |
| Courtois, A; Drenou, B; Fardel, O; Fauchet, R; Payen, L; Rault, B | 1 |
| Bukh, A; Clausen, N; Hokland, P; Langkjer, ST; Nørgaard, JM; Palshof, T | 1 |
| Archimbaud, E; Berneman, ZN; de Cataldo, R; Dekker, AW; Fillet, G; Haak, H; Hagemeijer, A; Hayat, M; Löwenberg, B; Solbu, G; Sonneveld, P; Stryckmans, P; Suciu, S; Thyss, A; van der Lelie, J; Visani, G; Zittoun, R | 1 |
| Bishop, JF; Bradstock, K; Lowenthal, RM; Matthews, JP; Young, GA | 1 |
| Löwenberg, B; Rutten, FF; Suciu, S; Uyl-de Groot, CA; Vellenga, E; Willemze, R | 1 |
| Büchner, T; Kessler, T; Schumacher, A; van de Loo, J; Wewers, D | 1 |
| Appelbaum, FR; Balcerzak, SP; Godwin, JE; Head, DR; Hynes, HE; Kopecky, KJ; Leith, CP; Willman, CL | 1 |
| Gray, RG; Hann, IM; Stevens, RF; Wheatley, K | 1 |
| Appelbaum, FR; Banker, DE; Groudine, M; Norwood, T; Willman, CL | 1 |
| Adachi, K; Marunouchi, T; Saito, H; Towatari, M | 1 |
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| Burke, PJ; Gore, SD; Weng, LJ | 1 |
| Hagiwara, S; Hirano, N; Miwa, A; Takezako, N; Togawa, A; Yuo, A | 1 |
| Arakawa, M; Chou, T; Emura, I; Ishiguro, T; Kakihara, T; Naito, M; Yoshizawa, H | 1 |
| An, E; Dan, K; Gomi, S; Kamikubo, K; Nomura, T; Ogata, K; Tamura, H; Yamada, T; Yokose, N | 1 |
| Arthur, DC; Berg, DT; Bloomfield, CD; Byrd, JC; Carroll, A; Davey, FR; Lawrence, D; Mayer, RJ; Patil, SR; Pettenati, MJ; Schiffer, CA; Tantravahi, R | 1 |
| Friedenberg, WR | 1 |
| Brunner, R; Filipits, M; Lechner, K; Pirker, R; Suchomel, RW; Zöchbauer, S | 1 |
| Baak, JP; Broxterman, HJ; Eekman, CA; Feller, N; Klumper, E; Kuiper, CM; Ossenkoppele, GJ; Pieters, R; Schuurhuis, GJ; van Heijningen, TH | 1 |
| Burke, PJ; Cowan, K; Gore, SD; Jones, RJ; Piantadosi, S; Weng, LJ; Zilcha, M | 1 |
| De La Rubia, J; Gomis, F; González-García, Y; Jarque, I; Martín, G; Pérez-Sirvent, M; Sanz, MA; Sempere, A; Senent, L | 1 |
| Bour, C; Colosetti, P; Guerci, AP; Guerci, O; Kataki, A; Marchal, S; Merlin, JL | 1 |
| Feliu, E; Hernández, JA; Millá, F; Navarro, JT; Oriol, A; Pujol, M; Ribera, JM; Sancho, JM | 1 |
| Broxterman, HJ; Eekman, CA; Lankelma, J; Loonen, AH; Löwenberg, B; Ossenkoppele, GJ; Pieters, R; Pinedo, HM; Schoester, M; Schuurhuis, GJ; Sonneveld, P | 1 |
| Björkholm, M; Gruber, A; Knaust, E; Macnamara, B; Palucka, KA; Peterson, C; Pisa, P; Porwit-Macdonald, A; Xu, D | 1 |
| Cammenga, J; Klampfer, L; Nimer, SD; Wisniewski, HG | 1 |
| Hillman, AL | 1 |
| Appelbaum, FR; Issa, JP; Kopecky, KJ; Li, Q; Mohan, A; Weick, JK; Willman, CL | 1 |
| Bettaïeb, A; Bordier, C; Kowalski-Chauvel, A; Laurent, G; Lautier, D; Mansat-De Mas, V; Payrastre, B; Plo, I; Rousse, A | 1 |
| Ehninger, G; Illmer, T; Neubauer, A; Nowak, R; Oelschlägel, U; Renner, U; Schaich, M; Subat, S; Ziegs, B | 1 |
| Aszalos, A; Molnár, J; Ocsovszki, I; Szabó, D; Szabó, G | 1 |
| Beauchamp-Nicoud, A; Legrand, O; Marie, JP; Simonin, G; Zittoun, R | 1 |
| Becton, DL; Buck, SA; Chang, MN; Huang, X; Massey, GV; Matherly, LH; Ravindranath, Y; Stout, ML; Taub, JW; Weinstein, HJ | 1 |
| Isaev, VG; Khoroshko, ND; Kliasova, GA; Kulikov, SM; Maslova, ER; Ol'shanskaia, IuV; Parovichnikova, EN; Pivnik, AV; Savchenko, VG; Tikhonova, LIu | 1 |
| Adachi, K; Asou, N; Hatake, K; Hiraoka, A; Jinnai, I; Kageyama, S; Kanamaru, A; Kobayashi, T; Kuriyama, K; Matsuda, S; Minami, S; Miyawaki, S; Oh, H; Ohno, R; Ohtake, S; Omoto, E; Saito, K; Sakamaki, H; Shimazaki, C; Takahashi, M; Takeyama, K; Tamura, J; Tanimoto, M; Tsubaki, K; Yamada, O | 1 |
| Hokland, P; Kristensen, JS; Nørgaard, JM; Olesen, G; Pedersen, B | 1 |
| Cortes, J; Estey, E; Giles, F; Kantarjian, H; Keating, M; O'Brien, S | 1 |
| Bauer, E; Clark, M; Gieseler, F; Nuessler, V; Valsamas, S | 1 |
| Baer, M; Caligiuri, M; Dodge, RK; George, SL; Lee, EJ; Lemke, S; Powell, BL; Schiffer, CA; Smith, R; Szatrowski, TP | 1 |
| Mandelli, F; Montefusco, E | 1 |
| Fujisawa, S; Harano, H; Ishigatsubo, Y; Kanamori, H; Mohri, H; Motomura, S; Tanabe, J | 1 |
| Eksborg, S; Lewensohn, R; Liliemark, E; Lindberg, A; Wang, Y | 1 |
| Bengtzen, S; Broberg, U; Lehmann, S; Paul, C | 1 |
| Borg, AG; Burgess, R; Green, LM; Liu Yin, JA; Scheper, RJ | 1 |
| Balduzzi, A; Galli, MA; Longoni, D; Nicolini, B; Tagliabue, A; Uderzo, C | 1 |
| den Boer, M; Lehne, G; Mørkrid, L; Rugstad, HE | 1 |
| Löfgren, C; Möllgård, L; Paul, C; Sundman-Engberg, B; Tidefelt, U | 1 |
| Gangadharan, VP; Jayasree, K; Nayak, N; Prakash, NP | 1 |
| Chithrathara, K; Elizabath, KA; Gangadharan, VP; Preetha, S; Sreejith, G | 1 |
| Arber, D; Dagis, A; Forman, SJ; Margolin, KA; Nademanee, A; Niland, J; O'Donnell, MR; Parker, PM; Schmidt, GM; Slovak, ML; Smith, EP; Snyder, DS; Somlo, G; Stein, AS | 1 |
| Agape, P; Belaud-Rotureau, MA; Belloc, F; Durrieu, F; Fitoussi, O; Labroille, G; Lacombe, F; Marit, G; Reiffers, J | 1 |
| Akiyama, H; Asou, N; Kitamura, K; Kiyoi, H; Kuriyama, K; Kusumoto, S; Minami, S; Miyawaki, S; Motoji, T; Nakano, Y; Naoe, T; Nishimura, M; Ohno, R; Saito, H; Saito, K; Shimazaki, C; Shinagawa, K | 1 |
| Arnoulet, C; Costello, RT; Gastaut, JA; Gaugler, B; Mallet, F; Olive, D; Sainty, D | 1 |
| Akasya, E; Büyükbabani, N; Diz-Küçükkaya, R; Oncü, S; Ozkaya-Bayazit, E; Pekçelen, Y | 1 |
| Lange, B | 1 |
| Gáliková, J; Haas, T; Lemez, P | 1 |
| Barbier, M; Boutonnat, J; Ronot, X; Seigneurin, D | 1 |
| Fukushima, T; Jinnai, I; Kuriyama, K; Matsuo, T; Miyazaki, Y; Moriuchi, Y; Taguchi, J; Tomonaga, M; Yoshida, S | 1 |
| Denault, A; Larouche, G; Prénovault, J | 1 |
| Appelbaum, FR; Banker, DE; Cooper, JJ; Garrido, SM; Kopecky, K; Willman, CL | 1 |
| Amenomori, T; Atogami, S; Fukushima, T; Hayashibara, T; Honda, M; Ikeda, S; Jinnai, I; Kuriyama, K; Kusano, M; Matsuo, T; Miyazaki, Y; Momita, S; Nagai, K; Nonaka, H; Soda, H; Taguchi, J; Tomonaga, M; Toriya, K; Yoshida, S; Yoshida, Y | 1 |
| Büchner, T; Fonatsch, C; Haase, D; Haferlach, T; Heinecke, A; Hiddemann, W; Löffler, H; Sauerland, MC; Schlegelberger, B; Schoch, C; Staib, P | 1 |
| Ehninger, G; Illmer, T; Lisske, P; Mohr, B; Neubauer, A; Ritter, M; Schaich, M; Schäkel, U; Thiede, C | 1 |
| de Witte, T; Linssen, P; Masereeuw, R; Muus, P; Raymakers, R; Smeets, M; Vierwinden, G | 1 |
| Dalton, W; Dorr, R; Greer, J; Grogan, T; Karanes, C; List, AF; Litchman, M; Moore, J; Pearce, T; Roe, D; Schiller, G; Spier, C; Weinberger, B | 1 |
| Buckley, DA; du Vivier, AW; Hopster, D; Keane, FM; Mufti, GJ; Munn, SE | 1 |
| Ashman, L; Cole, S; Ferrao, P; Sincock, P | 1 |
| Hokland, P; Langkjer, ST; Nørgaard, JM; Palshof, T; Pedersen, B | 1 |
| Büchner, T; Haferlach, T; Heinecke, A; Hiddemann, W; Sauerland, MC; Schoch, C | 1 |
| Burnett, AK; Liu Yin, JA; Rees, JK; Wheatley, K | 1 |
| Bishop, JF; Bradstock, KF; Cobcroft, RG; Dodds, AJ; Enno, A; Garson, OM; Gillett, EA; Hermann, RP; Joshua, DE; Juneja, SK; Lowenthal, RM; Ma, DD; Matthews, JP; Szer, J; Taylor, KM; Wolf, M; Young, GA | 1 |
| Bernasconi, P; Boni, M; Castoldi, GL; Ciolli, S; Clavio, M; Cox, MC; Cuneo, A; Del Poeta, G; Dini, D; Falzetti, D; Fanin, R; Gobbi, M; Isidori, A; Leoni, F; Liso, V; Malagola, M; Mandelli, F; Martinelli, G; Mecucci, C; Petti, MC; Piccaluga, PP; Rondelli, R; Russo, D; Sessarego, M; Specchia, G; Testoni, N; Torelli, G; Tura, S; Visani, G | 1 |
| Glimelius, B; Kimby, E; Nygren, P | 1 |
| Andreeff, M; Brenner, MK; Goodell, MA; Kuehnle, I; Marini, F; Wang, RY; Weidner, D; Wulf, GG | 1 |
| Burnett, AK; Clark, RE; Goldstone, AH; Hutchinson, RM; Smith, AG; Wheatley, K | 1 |
| Burnett, AK; Chatters, S; Goldstone, AH; Grimwade, D; Harrison, CJ; Harrison, G; Oliver, F; Walker, H; Wheatley, K | 1 |
| Andreesen, R; Aul, C; Balleisen, L; Berdel, W; Büchner, T; Eimermacher, H; Gassmann, W; Grüneisen, A; Haase, D; Haferlach, T; Hartlapp, J; Heinecke, A; Hiddemann, W; Hirschmann, WD; Löffler, H; Ludwig, WD; Maschmeyer, G; Pielken, HJ; Rasche, H; Reis, HE; Sauerland, MC; Schoch, C; Staib, P; Uhlig, J; Weh, HJ; Wörmann, B | 1 |
| Fujimaki, K; Fujisawa, S; Ishigatsubo, Y; Kanamori, H; Tanaka, M; Tomita, N; Yamaji, S | 1 |
| Elgie, AW; Maliepaard, M; Sargent, JM; Scheper, RJ; Taylor, CG; Williamson, CJ | 1 |
| Appelbaum, FR; Banker, DE; Cooper, JJ; Cotter, FE; Fennell, DA; Willman, CL | 1 |
| Anagnostopoulos, N; Androutsos, G; Galanopoulos, A; Kalmantis, T; Meletis, J; Paterakis, G; Rombos, Y; Sagriotis, A; Symeonidis, A; Tiniakou, M; Tsimberidou, AM; Yataganas, X; Zoumbos, N | 1 |
| Appelbaum, FR | 1 |
| Akiyama, H; Asou, N; Kiyoi, H; Kodera, Y; Kuriyama, K; Kusumoto, S; Miyawaki, S; Motoji, T; Naoe, T; Nishimura, M; Ohno, R; Saito, H; Saito, K; Shimazaki, C; Shinagawa, K; Tagawa, Y; Ueda, R | 1 |
| Iwakiri, R; Kumakawa, T; Mikoshiba, M; Mori, M; Ohta, M; Tsutsumi, H | 1 |
| Bendix, K; Hokland, P; Kjeldsen, E; Kristensen, JS; Meyer, K; Nørgaard, JM; Olesen, G; Olesen, LH; Pedersen, B | 1 |
| Gallagher, M; Garban, F; Jacob, MC; Jouvin-Marche, E; Marche, PN; Moine, A; Sotto, JJ | 1 |
| Ben-Am, M; Burnett, A; Capdeville, R; Dekker, A; Ferrant, C; Gratwohl, A; Kovacsovics, T; Löwenberg, B; Ossenkoppele, G; Pfister, C; Rosenkranz, G; Sonneveld, P; Vellenga, E; Verhoef, G; Vossebeld, P; Yin, L | 1 |
| Boswell, HS; Burgess, GS; Cripe, LD; Fyffe, J; Gabig, TG; Gelfanov, VM; Hartman, AD; Jung, SH; Kneebone, P; Mercola, D; Phillips, CA; Smith, EA; Spigel, DR | 1 |
| Chauvier, D; Manfait, M; Morjani, H | 1 |
| Barabash, G; Benjamin, D; Djaldetti, M; Douer, D; Pinkhas, J; Weinberger, A | 1 |
| Braine, HG; Burke, PJ; Karp, JE; Vaughan, WP | 1 |
| Buskard, NA; Catovsky, D; Costello, C; Galton, DA; Goldman, JM; Spiers, AS | 1 |
| Auclerc, MF; Holland, JF; Jacquillat, C; Schaison, G; Weil, M | 1 |
| Holland, JF; Silver, RT; Young, RC | 1 |
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| Kawashima, K; Ogata, K; Watanabe, E; Yamada, K | 1 |
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| Brucksch, KP; Busch, H; Käding, J; Meshkov, T; Schmidt, CG; Seeber, S | 1 |
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| Brodsky, I; Conroy, JF; Fuscaldo, KE; Kahn, SB; Lamping, CG | 1 |
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| Furusawa, S; Nagashima, S; Saito, K; Shishido, H; Waga, K | 1 |
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| Curtis, JE; Lipton, JH; Lockwood, GA; McCulloch, EA; Messner, HA; Minden, MD; Tritchler, DL | 1 |
| Isaev, VG; Kulikov, SM; Parovichnikova, EN; Sarycheva, TG; Savchenko, VG; Tikhonova, LIu | 1 |
| Gau, JP; Hu, HT; Hwang, WL; Tsai, YT; Young, JH | 1 |
| Büchner, T; Hiddemann, W; Kewer, U; Reuter, C; Rolf, C; Schleyer, E; Uhrmeister, C; Unterhalt, M; Wörmann, B; Zühlsdorf, M | 1 |
| Fukushima, T; Nakamura, T; Ueda, T | 1 |
| Bennett, JM; Cassileth, PA; Edelstein, M; Harrington, DP; Hines, JD; Lynch, E; Mazza, JJ; McGlave, PB; O'Connell, MJ; Oken, MM | 1 |
| Abgrall, JF; Desablens, B; Dufour, P; Guyotat, D; Harousseau, JL; Herve, P; Ifrah, N; Milpied, N; Pignon, B; Solary, E | 1 |
| Attal, M; Blaise, D; Cony-Makhoul, P; Corront, B; Gastaut, JA; Marit, G; Michallet, M; Reiffers, J; Rigal-Huguet, F; Stoppa, AM | 1 |
| Civin, C; Gresik, M; Krischer, J; Ravindranath, Y; Steuber, P; Vietti, T; Weinstein, H | 1 |
| Amadori, S; Giona, F; Giuliano, M; Mandelli, F; Moleti, ML; Pession, A; Rolla, M; Rondelli, R; Testi, AM | 1 |
| Gray, R; Hann, IM; Stevens, RF; Wheatley, K | 1 |
| Berg, DT; Davis, RB; Frei, E; Mayer, RJ; Sarno, E; Schiffer, CA | 1 |
| Aul, C; Büchner, T; Hiddemann, W; Hossfeld, D; Löffler, H; Ludwig, WD; Maschmeyer, G; Nowrousian, M; Schaefer, UW; Wörmann, B | 1 |
| Caronia, F; de Witte, T; Gattringer, C; Leoni, P; Liso, V; Mandelli, F; Petti, MC; Resegotti, L; Rotoli, B; Zittoun, R | 1 |
| Asoh, N; Hiraoka, A; Imai, K; Kobayashi, T; Kodera, K; Morishima, Y; Ohno, R; Takahashi, I; Tomonaga, M; Tsubaki, K | 1 |
| Ames, MM; Kuffel, MJ; Reid, JM | 1 |
| Jäger, U; Köller, U; Koller-Weber, E; Marosi, C; Nowotny, H; Pirc-Danoewinata, H; Schneider, B; Schwarzinger, I; Steger, G; Vahls, P | 1 |
| Anglaret, B; Archimbaud, E; Devaux, Y; Ffrench, M; Fiere, D; Sebban, C; Thomas, X; Troncy, J | 1 |
| Caballero, MD; Cañizo, MC; González, M; Nieto, MJ; Orfao, A; San Miguel, JF | 1 |
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| Bernabei, PA; D'Ippolito, G; Dal Pozzo, O; Fenigli, S; Lombardini, L; Rossi Ferrini, P | 1 |
| Büchner, T; Gassmann, W; Heit, W; Hiddemann, W; Hossfeld, D; Löffler, G; Ludwig, WD; Maschmeyer, G; Thiel, E; Weh, H | 1 |
| Briere, J; Casassus, P; Desablens, B; Gandhour, B; Harousseau, JL; Ifrah, N; Leprise, PY; Milpied, N | 2 |
| Ito, T; Ito, Y; Kitaori, K; Nagai, T; Ohno, R; Okumura, M; Sugiura, I; Takeo, T; Yano, K; Yokomaku, S | 1 |
| Chen, Z; Chu, Y; Liu, J; Qi, S; Yang, C; Yin, S; Zhu, Z | 1 |
| Boeckmann, A; Freire, EA; Frisch, J; Hiddemann, W; Innig, G; Reuter, C; Rottmann, R; Schulz, G; Wörmann, B; Zühlsdorf, M | 1 |
| Grassi, D; Tartas, N | 1 |
| Caplan, S; Davis, RB; Dillman, RO; Gottlieb, AJ; Green, MR; Kopel, S; McIntyre, OR; Preisler, H; Schiffer, C; Weiss, RB | 1 |
| Center, MS; Marquardt, D | 1 |
| Boeckmann, A; Büchner, T; Freire, EA; Hiddemann, W; Innig, G; Koenigsmann, M; Ludwig, WD; Maschmeyer, G; Wörmann, B; Zühlsdorf, M | 1 |
| Boesch, D; Loor, F; Muller, K; Pourtier-Manzanedo, A | 1 |
| Almqvist, A; Elonen, E; Hänninen, A; Järventie, G; Jouppila, J; Kätkä, K; Koivunen, E; Lahtinen, R; Oivanen, T; Palva, IP | 1 |
| Hedenus, M; Hörnsten, P; Malm, C; Wahlin, A | 1 |
| Anderson, H; Chang, J; Deakin, DP; Heron, D; Morgenstern, GR; Oppenheim, B; Ranson, MR; Ryder, D; Scarffe, JH | 1 |
| Close, P; Meister, L; Ruchelli, E | 1 |
| Fishbein, G; Iseri, O; Knodell, RG; Rosen, AA | 1 |
| Farhi, DC; Rosenthal, NS | 1 |
| Daly, KM; Gore, S; Larson, RA; Le Beau, MM; Lukin, CL; Mick, R | 1 |
| Conard, P; Gaynon, P; Johnson, FL; Kowal-Vern, A; Nachman, J; Radhakrishnan, J; Trujillo, Y | 1 |
| Ekberg, M; Larsson, R; Nygren, P; Slater, L | 1 |
| Boyett, J; Kitchens, CS; Kramer, BS; Noyes, WD; Oblon, DJ; Ross, W; Weiner, RS | 1 |
| Arkin, H; Holland, JF; Ohnuma, T | 1 |
| Chan, HS; Estrov, Z; Freedman, MH; Weitzman, SS | 1 |
| Baker, MA; Bhalla, K; Gervasoni, JE; Hindenburg, AA; Krishna, S; Lutzky, J; Rosado, M; Stewart, VJ; Taub, RN | 1 |
| Cooper, B; Fay, JW; Flexner, JM; Greer, JP; Herzig, GP; Herzig, RH; Lazarus, HM; Phillips, GL; Stein, RS; Wolff, SN | 1 |
| Kobayashi, T | 1 |
| Bolwell, BJ; Cassileth, PA; Gale, RP | 1 |
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| Bourguignat, A; Eydoux, P; Floiras, JL; Le Doussal, V; Trassard, M; Turpin, F | 1 |
| Battista, R; D'Emilio, A; Dini, E; Pacciarini, MA; Vespignani, M | 1 |
| Kimura, I; Kitani, T; Masaoka, T; Meguro, S; Nagai, K; Ogawa, M; Ohnoshi, T; Sampi, K; Wakui, A; Yamada, K | 1 |
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| Benetton, G; Blasi, E; Clayton, M; Gronberg, A; Radzioch, D; Tonini, GP; Varesio, L | 1 |
| Kitani, T; Machii, T; Nakamura, Y; Nishimoto, M; Shibano, M; Taniguchi, N; Ueda, E; Waki, K | 1 |
| Farley, B; Giuliano, R; LaBella, S; Leary, JF; Ohlsson-Wilhelm, BM; Rowley, PT | 1 |
| Kariyone, S; Kimura, H; Kokubun, K; Matsuda, S; Sakai, K; Shineha, H; Uchida, T; Yoshida, M; Yui, T | 1 |
| Balaian, LN; Kravtsova, VM; Patterson, D; Petrova, EM; Zabelina, TS | 1 |
| Ahmed, NK; Vasanthakumar, G | 2 |
| Barlogie, B; Freireich, EJ; Hester, J; Kantarjian, HM; Keating, MJ; McCredie, KB; Smith, T; Trujillo, J; Vellekoop, L | 1 |
| Ardeman, S; Greene, ML; Ruddell, K; Schey, SA | 1 |
| Arlin, ZA; Berman, E; Chaganti, RS; Clarkson, BD; Gee, T; Jhanwar, SC; Kurland, E; Mertelsmann, R; Moore, MA | 1 |
| Clark, M; Dale, NL; Garvin, DF; Hummer, W; Schumacher, HR; Stark, EW; Surana, RB | 1 |
| Birgens, HS; Geisler, C; Hansen, NE; Hasselbalch, H | 1 |
| Bligham, G; Freireich, EJ; Gehan, E; Hester, JP; Kantarjian, HM; Keating, MJ; McCredie, KB; Smith, TL; Talpaz, M; Walters, RS | 1 |
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| Bernard, J; Blom, J; Boiron, M; Brunner, K; Cooper, MR; Cuttner, J; Ellison, RR; Gailani, S; Glidewell, OJ; Haurani, F; Holland, JF; Hoogstraten, B; Jacquillat, C; Levy, R; Lowenstein, L; Nissen, NI; Rege, VB; Serpick, AA; Silver, RT; Wasserman, L; Weil, M; Wiernik, PH | 1 |
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25 review(s) available for daunorubicin and Granulocytic Leukemia
| Article | Year |
|---|---|
Optimal induction and post-remission therapy for AML in first remission.
Topics: Acute Disease; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Graft vs Leukemia Effect; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Living Donors; Middle Aged; Multicenter Studies as Topic; Prospective Studies; Randomized Controlled Trials as Topic; Remission Induction; Survival Rate; Young Adult | 2009 |
Understanding and treating opioid addiction in a patient with cancer pain.
Topics: Adult; Analgesics, Opioid; Antineoplastic Agents; Brain; Cytarabine; Daunorubicin; Heroin Dependence; Hormones; Humans; Hydromorphone; Leukemia, Myeloid; Male; Pain | 2011 |
Viridans streptococcal sepsis: clinical features and complications in childhood acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Chromosome Aberrations; Combined Modality Therapy; Cytarabine; Daunorubicin; Deoxyadenosines; Double-Blind Method; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Hypotension; Immunocompromised Host; Leukemia, Myeloid; Male; Mycoses; Neutropenia; Randomized Controlled Trials as Topic; Respiratory Distress Syndrome; Retrospective Studies; Sepsis; Streptococcal Infections; Viridans Streptococci | 2003 |
Secondary acute leukemia following mitoxantrone-based high-dose chemotherapy for primary breast cancer patients.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Epirubicin; Female; Humans; Incidence; Leukemia, Myeloid; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Leukemia, Radiation-Induced; Lymphatic Metastasis; Melphalan; Middle Aged; Mitoxantrone; Neoplasms, Second Primary; Paclitaxel; Peripheral Blood Stem Cell Transplantation; Radiotherapy, Adjuvant; Thiotepa; Transplantation Conditioning; Transplantation, Autologous | 2003 |
Chronic granulocytic leukemia.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow Transplantation; Busulfan; Chromosomes, Human, 21-22 and Y; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Hydroxyurea; Leukapheresis; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Palliative Care; Prednisolone; Prednisone; Thioguanine; Vincristine | 1984 |
Adult acute nonlymphocytic leukemias.
Topics: Acute Disease; Aged; Anemia; Anemia, Aplastic; Anemia, Sideroblastic; Blood Transfusion; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Drug Resistance; Female; Hemorrhage; Humans; Immunotherapy; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Platelet Transfusion; Spinal Cord; Syndrome | 1980 |
A syndrome of lymphoblastic lymphoma, eosinophilia, and myeloid hyperplasia/malignancy associated with t(8;13)(p11;q11): description of a distinctive clinicopathologic entity.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Transplantation; Carboplatin; Chromosomes, Human, Pair 13; Chromosomes, Human, Pair 8; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Eosinophilia; Etoposide; Fatal Outcome; Female; Humans; Hydroxyurea; Hyperplasia; Ifosfamide; Leukemia, Myeloid; Lymph Nodes; Male; Middle Aged; Mitoxantrone; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Pregnancy; Pregnancy Complications, Neoplastic; Remission Induction; Syndrome; Translocation, Genetic; Vincristine | 1995 |
Two additional cases of acute myeloid leukemia with t(7;11)(p15;p15) having low neutrophil alkaline phosphatase scores.
Topics: Acute Disease; Adult; Alkaline Phosphatase; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 7; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Neutrophils; Prednisolone; Primary Myelofibrosis; Remission Induction; Translocation, Genetic | 1993 |
Intensified induction chemotherapy with high dose cytarabine and etoposide for acute myeloid leukemia: a review and updated results of the Australian Leukemia Study Group.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Etoposide; Humans; Leukemia, Myeloid; Remission Induction | 1998 |
A systematic collaborative overview of randomized trials comparing idarubicin with daunorubicin (or other anthracyclines) as induction therapy for acute myeloid leukaemia. AML Collaborative Group.
Topics: Acute Disease; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Randomized Controlled Trials as Topic; Remission Induction; Survival Analysis | 1998 |
[Treatment of acute and chronic leukemias].
Topics: Acute Disease; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chromosome Aberrations; Combined Modality Therapy; Daunorubicin; Humans; Idarubicin; Karyotyping; Leukemia; Leukemia, Hairy Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Randomized Controlled Trials as Topic; Transplantation, Autologous; Transplantation, Homologous | 1999 |
The management of neoplastic disorders of haematopoiesis in children with Down's syndrome.
Topics: Acute Disease; Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Down Syndrome; Female; Genetic Predisposition to Disease; Humans; Infant; Infant, Newborn; Leukemia; Leukemia, Myeloid; Male; Maternal Age; Myeloproliferative Disorders; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone; Remission Induction; Vincristine | 2000 |
Acute myeloid leukaemia (AML): treatment of the older patient.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid; Middle Aged; Treatment Outcome | 2001 |
The prognostic value of cytogenetics is reinforced by the kind of induction/consolidation therapy in influencing the outcome of acute myeloid leukemia--analysis of 848 patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Deletion; Chromosome Inversion; Chromosomes, Human; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Hepatomegaly; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prognosis; Remission Induction; Retrospective Studies; Splenomegaly; Survival Analysis; Translocation, Genetic; Treatment Outcome | 2001 |
A systematic overview of chemotherapy effects in acute myeloid leukaemia.
Topics: Acute Disease; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Humans; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Neoplasms, Second Primary; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; Treatment Outcome | 2001 |
Consequences of acute myelogenous leukemia in early pregnancy.
Topics: Abortion, Therapeutic; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Infant Mortality; Infant, Newborn; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Pregnancy; Pregnancy Complications, Hematologic; Pregnancy Trimester, First; Pregnancy Trimester, Second; Risk; Teratogens; Thioguanine; Vincristine | 1977 |
[Prognostic significance of cytochemical findings in differentiated myelogenous leukaemias of adults (author's transl)].
Topics: Acid Phosphatase; Adult; Aged; Alkaline Phosphatase; Bone Marrow Cells; Cerebral Hemorrhage; Daunorubicin; Female; Gastrointestinal Hemorrhage; Glucuronidase; Humans; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Middle Aged; Monocytes; Muramidase; Naphthol AS D Esterase; Periodic Acid-Schiff Reaction; Peroxidases; Pregnancy; Prognosis; Remission, Spontaneous | 1977 |
Management of acute leukemia in adults.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Blood Transfusion; Cytarabine; Daunorubicin; Drug Therapy, Combination; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Middle Aged; Prognosis; Remission, Spontaneous; Thioguanine; Thrombocytopenia; Time Factors | 1975 |
[Therapy of leukemia].
Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Adult; Age Factors; Antimetabolites, Antineoplastic; Asparaginase; Child; Chronic Disease; Cyclophosphamide; Daunorubicin; Doxorubicin; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Vincristine | 1976 |
Improved cure rate by very early intensification combined with prolonged maintenance chemotherapy in patients with acute myeloid leukemia: data from the AML Cooperative Group.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid; Remission Induction; Thioguanine | 1991 |
New agents in the treatment of acute myeloid leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cytarabine; Daunorubicin; Drug Evaluation; Etoposide; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Remission Induction; Tretinoin | 1991 |
Granulocytic sarcoma of the ileum treated by bone marrow transplantation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Combined Modality Therapy; Cytarabine; Daunorubicin; Graft vs Host Disease; Humans; Ileal Neoplasms; Leukemia, Myeloid; Male; Methotrexate; Remission Induction; Whole-Body Irradiation | 1991 |
High dose cytarabine: a review.
Topics: Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Cytarabine; Daunorubicin; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Pancytopenia | 1988 |
Combination chemotherapy for lymphomas and leukemias.
Topics: Adult; Burkitt Lymphoma; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Combinations; Hodgkin Disease; Humans; Immunotherapy; Infections; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphoma; Mercaptopurine; Methotrexate; Middle Aged; Nitrogen Mustard Compounds; Prednisone; Procarbazine; Prognosis; Remission, Spontaneous; Vincristine | 1973 |
Treatment of acute granulocytic leukemias.
Topics: Adult; Age Factors; Antineoplastic Agents; Blood Cell Count; Blood Platelets; Bone Marrow Examination; Child; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Heart; Hemorrhage; Humans; Hydrazones; Injections, Intravenous; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocyte Count | 1974 |
119 trial(s) available for daunorubicin and Granulocytic Leukemia
| Article | Year |
|---|---|
Unsatisfactory efficacy in randomized study of reduced-dose CPX-351 for medically less fit adults with newly diagnosed acute myeloid leukemia or other high-grade myeloid neoplasm.
Topics: Adult; Aged; Aged, 80 and over; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Physical Fitness; Survival Analysis; Treatment Outcome | 2018 |
Combination of cladribine and cytarabine is effective for childhood acute myeloid leukemia: results of the St Jude AML97 trial.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cladribine; Combined Modality Therapy; Cytarabine; Daunorubicin; Down Syndrome; Drug Administration Schedule; Etoposide; Hematopoietic Stem Cell Transplantation; Humans; Infant; Kaplan-Meier Estimate; Leukemia, Myeloid; Myelodysplastic Syndromes; Prognosis; Proportional Hazards Models; Remission Induction; Young Adult | 2009 |
Citrulline as a marker for chemotherapy induced mucosal barrier injury in pediatric patients.
Topics: Acute Disease; Adolescent; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Carbohydrates; Cell Death; Child; Child, Preschool; Citrulline; Cytarabine; Daunorubicin; DNA; Enterocytes; Etoposide; Feces; Female; Humans; Infant; Interleukin-8; Intestinal Absorption; Leukemia, Myeloid; Leukocyte L1 Antigen Complex; Male; Mitoxantrone; Models, Biological; Mucositis; Stomatitis | 2009 |
Daunorubicin versus mitoxantrone versus idarubicin as induction and consolidation chemotherapy for adults with acute myeloid leukemia: the EORTC and GIMEMA Groups Study AML-10.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Remission Induction; Survival Analysis; Survival Rate; Treatment Outcome; Young Adult | 2009 |
Phase 1 study of epigenetic priming with decitabine prior to standard induction chemotherapy for patients with AML.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cytarabine; Daunorubicin; Decitabine; Diarrhea; DNA Methylation; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Fever; Humans; Infections; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Middle Aged; Nausea; Neutropenia; Treatment Outcome; Young Adult | 2011 |
Favorable survival maintained in children who have myeloid leukemia associated with Down syndrome using reduced-dose chemotherapy on Children's Oncology Group trial A2971: a report from the Children's Oncology Group.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Down Syndrome; Drug Administration Schedule; Etoposide; Female; Humans; Infant; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Thioguanine; Treatment Outcome | 2012 |
Postremission therapy with low-dose interleukin 2 with or without intermediate pulse dose interleukin 2 therapy is well tolerated in elderly patients with acute myeloid leukemia: Cancer and Leukemia Group B study 9420.
Topics: Acute Disease; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cyclosporins; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Etoposide; Fatigue; Gene Expression Regulation, Neoplastic; Hematologic Diseases; Humans; Immunologic Factors; Interleukin-2; Killer Cells, Natural; Leukemia, Myeloid; Life Tables; Middle Aged; Nausea; Neoplasm Proteins; NK Cell Lectin-Like Receptor Subfamily K; Receptors, Immunologic; Receptors, Natural Killer Cell; Recombinant Fusion Proteins; Remission Induction; Survival Analysis; Treatment Outcome | 2002 |
Outcome after induction chemotherapy for older patients with acute myeloid leukemia is not improved with mitoxantrone and etoposide compared to cytarabine and daunorubicin: a Southwest Oncology Group study.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Remission Induction; Survival Analysis; Survival Rate; Treatment Outcome | 2002 |
Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461).
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Inversion; Chromosomes, Human; Cytarabine; Daunorubicin; Disease-Free Survival; Follow-Up Studies; Humans; Incidence; Karyotyping; Leukemia, Myeloid; Life Tables; Prospective Studies; Recurrence; Remission Induction; Risk Factors; Survival Analysis; Translocation, Genetic; Treatment Outcome; Trisomy | 2002 |
Impact of granulocyte colony-stimulating factor use during induction for acute myelogenous leukemia in children: a report from the Children's Cancer Group.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Child; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Etoposide; Female; Filgrastim; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Hyperbilirubinemia; Infection Control; Length of Stay; Leukemia, Myeloid; Male; Neutropenia; Prospective Studies; Recombinant Proteins; Remission Induction; Survival Analysis; Thioguanine; Thrombocytosis; Treatment Outcome | 2002 |
Intensified daunorubicin in induction therapy and autologous peripheral blood stem cell transplantation in postremission therapy (Double-7 protocol) for adult acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Daunorubicin; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Peripheral Blood Stem Cell Transplantation; Remission Induction; Survival Analysis; Transplantation, Autologous; Treatment Outcome | 2002 |
A phase I/II study of the MDR modulator Valspodar (PSC 833) combined with daunorubicin and cytarabine in patients with relapsed and primary refractory acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cause of Death; Cyclosporins; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Humans; Leukemia, Myeloid; Middle Aged; Remission Induction; Salvage Therapy; Treatment Outcome | 2003 |
BAALC expression predicts clinical outcome of de novo acute myeloid leukemia patients with normal cytogenetics: a Cancer and Leukemia Group B Study.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Genetic Markers; Genetic Predisposition to Disease; Humans; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Multivariate Analysis; Neoplasm Proteins; Predictive Value of Tests; Prognosis; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; Treatment Outcome | 2003 |
Population pharmacokinetics of liposomal daunorubicin in children.
Topics: Acute Disease; Adolescent; Adult; Antibiotics, Antineoplastic; Child; Child, Preschool; Daunorubicin; Drug Carriers; Humans; Infant; Infusions, Intravenous; Leukemia, Myeloid; Liposomes; Neoplasms; Recurrence | 2003 |
No benefit from adding GM-CSF to induction chemotherapy in transforming myelodysplastic syndromes: better outcome in patients with less proliferative disease.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Cell Transformation, Neoplastic; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Prospective Studies; Remission Induction; Survival Rate; Thioguanine | 2003 |
Pilot study of idarubicin-based intensive-timing induction therapy for children with previously untreated acute myeloid leukemia: Children's Cancer Group Study 2941.
Topics: Acute Disease; Adolescent; Adult; Antibiotics, Antineoplastic; Child; Child, Preschool; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Humans; Idarubicin; Infant; Infant, Newborn; Leukemia, Myeloid; Male; Thioguanine; Treatment Outcome | 2004 |
[Consolidation of therapy of acute myeloid leukemia with the AML-BFM 93 protocol in children in the Czech Republic].
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Infant; Leukemia, Myeloid; Male | 2004 |
Increasing dose intensity of anthracycline antibiotics improves outcome in patients with acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Dose-Response Relationship, Drug; Doxorubicin; Etoposide; Female; Follow-Up Studies; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Male; Middle Aged; Proportional Hazards Models; Prospective Studies; Remission Induction; Survival Analysis; Treatment Outcome | 2004 |
Combination of liposomal daunorubicin (DaunoXome), fludarabine, and cytarabine (FLAD) in patients with poor-risk acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Risk Factors; Survival Rate; Vidarabine | 2004 |
Dose escalation studies of cytarabine, daunorubicin, and etoposide with and without multidrug resistance modulation with PSC-833 in untreated adults with acute myeloid leukemia younger than 60 years: final induction results of Cancer and Leukemia Group B
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclosporins; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Leukemia, Myeloid; Logistic Models; Male; Middle Aged; Survival Analysis; Treatment Outcome | 2004 |
Outcome of induction and postremission therapy in younger adults with acute myeloid leukemia with normal karyotype: a cancer and leukemia group B study.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Benzoquinones; Cyclophosphamide; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prognosis; Recurrence; Splenomegaly; Survival Analysis; Treatment Outcome | 2005 |
Induction chemotherapy for acute myelogenous leukemia.
Topics: Acute Disease; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Etoposide; Humans; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Remission Induction; Survival Analysis; Treatment Outcome | 2005 |
Prediction of individual response to chemotherapy in patients with acute myeloid leukaemia using the chemosensitivity index Ci.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Screening Assays, Antitumor; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Predictive Value of Tests; Prospective Studies; Sensitivity and Specificity; Survival Analysis; Thioguanine; Treatment Outcome; Tumor Cells, Cultured | 2005 |
Treatment for myeloid leukaemia of Down syndrome: population-based experience in the UK and results from the Medical Research Council AML 10 and AML 12 trials.
Topics: Adolescent; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Cytogenetic Analysis; Daunorubicin; Down Syndrome; Drug Administration Schedule; Etoposide; Female; Humans; Infant; Leukemia, Myeloid; Leukocyte Count; Male; Mitoxantrone; Thioguanine; Treatment Outcome; United Kingdom | 2006 |
Remission induction chemotherapy induces in vivo caspase-dependent apoptosis in bone marrow acute myeloid leukemia blast cells and spares lymphocytes.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Agents; Apoptosis; Bone Marrow Cells; Bone Marrow Transplantation; Caspases; Cell Count; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Flow Cytometry; Humans; Idarubicin; Leukemia, Myeloid; Leukocyte Common Antigens; Leukocyte Count; Lymphocytes; Male; Middle Aged; Prognosis; Remission Induction | 2006 |
Early prediction of therapy response in patients with acute myeloid leukemia by nucleosomal DNA fragments.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Cytarabine; Daunorubicin; DNA Fragmentation; Female; Humans; L-Lactate Dehydrogenase; Leukemia, Myeloid; Leukocytes; Male; Middle Aged; Mitoxantrone; Nucleosomes; Predictive Value of Tests; Prognosis; Thioguanine; Thymidine Kinase; Treatment Outcome | 2006 |
Less toxicity by optimizing chemotherapy, but not by addition of granulocyte colony-stimulating factor in children and adolescents with acute myeloid leukemia: results of AML-BFM 98.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cranial Irradiation; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Female; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Infant; Infections; Leukemia, Myeloid; Male; Mitoxantrone; Neutropenia; Radiotherapy, Adjuvant; Risk Assessment; Risk Factors; Survival Analysis; Treatment Outcome | 2006 |
Intensifying daunorubicin in induction for patients with core binding factor leukemia.
Topics: Adolescent; Adult; Antibiotics, Antineoplastic; Daunorubicin; Disease-Free Survival; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Survival Rate; Treatment Outcome | 2006 |
Effect of priming with granulocyte-macrophage colony-stimulating factor in younger adults with newly diagnosed acute myeloid leukemia: a trial by the Acute Leukemia French Association (ALFA) Group.
Topics: Acute Disease; Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplastic Stem Cells; Premedication; Proportional Hazards Models; Recombinant Proteins; Risk; Salvage Therapy; Stimulation, Chemical; Transplantation, Homologous; Treatment Outcome | 2007 |
Postremission treatment of elderly patients with acute myeloid leukemia in first complete remission after intensive induction chemotherapy: results of the multicenter randomized Acute Leukemia French Association (ALFA) 9803 trial.
Topics: Acute Disease; Aged; Aged, 80 and over; Anthracyclines; Antibiotics, Antineoplastic; Blood Transfusion; Daunorubicin; Disease-Free Survival; Female; Hospitalization; Humans; Idarubicin; Leukemia, Myeloid; Male; Remission Induction; Survival Rate | 2007 |
The quality of molecular response to chemotherapy is predictive for the outcome of AML1-ETO-positive AML and is independent of pretreatment risk factors.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Core Binding Factor Alpha 2 Subunit; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Oncogene Proteins, Fusion; Prognosis; Remission Induction; Risk Factors; RNA, Messenger; RUNX1 Translocation Partner 1 Protein; Thioguanine | 2007 |
Modeling of in vitro drug activity and prediction of clinical outcome in acute myeloid leukemia.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Cytarabine; Daunorubicin; Humans; In Vitro Techniques; Leukemia, Myeloid; Models, Biological; Nonlinear Dynamics; Prognosis; Retrospective Studies; Spectrometry, Fluorescence; Treatment Outcome; Tumor Cells, Cultured | 2007 |
Results of a prospective randomized trial of early splenectomy in chronic myeloid leukemia. The Italian Cooperative Study Group on Chronic Myeloid Leukemia.
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Combined Modality Therapy; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Random Allocation; Splenectomy; Thioguanine; Time Factors | 1984 |
Chemotherapy of the myeloid leukaemias.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Busulfan; Child; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Preleukemia; Remission, Spontaneous; Thioguanine | 1980 |
[The results of 2 and 1/2 years of work of the Russian Multicenter Trial on the Treatment of Acute Myeloid Leukemias in Adults].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Remission Induction; Russia; Survival Analysis; Time Factors | 1995 |
Long-term outcome of postremission chemotherapy for adults with acute myeloid leukemia using different dose-intensities.
Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Germany; Humans; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Opportunistic Infections; Patient Acceptance of Health Care; Preleukemia; Prospective Studies; Remission Induction; Salvage Therapy; Survival Analysis; Treatment Outcome; Vincristine | 1994 |
L-asparaginase may potentiate the leukemogenic effect of the epipodophyllotoxins.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Synergism; Etoposide; Humans; Infant; Karyotyping; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Neoplasms, Second Primary; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prednisone | 1995 |
Clinical significance of surface antigen expression in children with acute myeloid leukemia: results of study AML-BFM-87.
Topics: Acute Disease; Adolescent; Antibodies, Monoclonal; Antigens, CD; Antigens, Neoplasm; Antigens, Surface; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Child; Child, Preschool; Chromosome Aberrations; Combined Modality Therapy; Cranial Irradiation; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Humans; Immunophenotyping; Infant; Leukemia, Myeloid; Neoplastic Stem Cells; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Sensitivity and Specificity; Treatment Outcome | 1995 |
A randomized placebo-controlled phase III study of granulocyte-macrophage colony-stimulating factor in adult patients (> 55 to 70 years of age) with acute myelogenous leukemia: a study of the Eastern Cooperative Oncology Group (E1490).
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Examination; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Double-Blind Method; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunologic Factors; Length of Stay; Leukemia, Myeloid; Male; Middle Aged; Neutropenia; Prospective Studies; Recombinant Proteins; Remission Induction; Survival Analysis; Treatment Outcome | 1995 |
No increase of leukemia relapse in newly diagnosed patients with acute myeloid leukemia who received granulocyte colony-stimulating factor for life-threatening infection during remission induction and consolidation therapy. Japan Adult Leukemia Study Grou
Topics: Acute Disease; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Communicable Diseases; Cytarabine; Daunorubicin; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Mercaptopurine; Prednisolone; Recombinant Proteins; Recurrence; Remission Induction; Survival Analysis; Time Factors; Vincristine | 1993 |
The treatment of older adult patients with acute myeloid leukemia by triple infusion chemotherapy.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Humans; Infusions, Intravenous; Leukemia, Myeloid; Middle Aged; Remission Induction; Survival Rate | 1995 |
MDR1 RNA expression as a prognostic factor in acute myeloid leukemia: an update.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cytarabine; Daunorubicin; Drug Resistance; Female; Follow-Up Studies; Gene Expression; Humans; Idarubicin; Leukemia, Myeloid; Male; Membrane Glycoproteins; Middle Aged; Prognosis; Remission Induction; RNA, Neoplasm; Survival Rate; Treatment Outcome | 1993 |
Daunorubicin pharmacokinetics and the correlation with P-glycoprotein and response in patients with acute leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Daunorubicin; Female; Humans; Leukemia, Myeloid; Male; Membrane Glycoproteins; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction | 1994 |
Comparison of survival. Chemotherapeutically treated and untreated older patient with acute myeloid leukemia.
Topics: Acute Disease; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Sex Factors; Survival Rate; Thioguanine | 1994 |
[The results of a multicenter cooperative study on treating acute myeloid leukemias in adults].
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Russia | 1994 |
Intensive postremission chemotherapy in adults with acute myeloid leukemia. Cancer and Leukemia Group B.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Survival Rate | 1994 |
Phase I/II trial of cyclosporine as a chemotherapy-resistance modifier in acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Child; Child, Preschool; Cyclosporine; Daunorubicin; Drug Resistance; Female; Gene Expression; Humans; Leukemia, Myeloid; Male; Membrane Glycoproteins; Middle Aged; Neoplasm Proteins; Phenotype; Survival Analysis; Treatment Outcome | 1993 |
Nationwide randomized comparative study of daunorubicin and aclarubicin in combination with behenoyl cytosine arabinoside, 6-mercaptopurine, and prednisolone for previously untreated acute myeloid leukemia.
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Prednisolone; Prospective Studies; Survival Analysis | 1994 |
Oral induction and consolidation of acute myeloid leukemia with etoposide, 6-thioguanine, and idarubicin (ETI) in elderly patients: a randomized comparison with 5-day TAD. Finnish Leukemia Group.
Topics: Acute Disease; Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Idarubicin; Injections, Intravenous; Leukemia, Myeloid; Male; Remission Induction; Thioguanine | 1994 |
Randomized study of individualized induction therapy with or without vincristine, and of maintenance-intensification therapy between 4 or 12 courses in adult acute myeloid leukemia. AML-87 Study of the Japan Adult Leukemia Study Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Prednisolone; Prospective Studies; Remission Induction; Survival Rate; Time Factors; Vincristine | 1993 |
Randomized trials between behenoyl cytarabine and cytarabine in combination induction and consolidation therapy, and with or without ubenimex after maintenance/intensification therapy in adult acute myeloid leukemia. The Japan Leukemia Study Group.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chi-Square Distribution; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Follow-Up Studies; Humans; Leucine; Leukemia, Myeloid; Logistic Models; Male; Mercaptopurine; Middle Aged; Multivariate Analysis; Prednisolone; Prospective Studies; Remission Induction; Survival Rate; Treatment Outcome | 1996 |
Oral idarubicin pharmacokinetics--correlation of trough level with idarubicin area under curve.
Topics: Acute Disease; Administration, Oral; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chromatography, High Pressure Liquid; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Idarubicin; Leukemia, Myeloid; Lymphoma, Non-Hodgkin; Metabolic Clearance Rate; Middle Aged | 1996 |
Autologous bone marrow transplantation versus intensive consolidation chemotherapy for acute myeloid leukemia in childhood. Pediatric Oncology Group.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Humans; Infant; Infant, Newborn; Leukemia, Myeloid; Survival Analysis; Thioguanine; Transplantation, Autologous | 1996 |
A randomized study of high-dose cytarabine in induction in acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Central Nervous System Diseases; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Etoposide; Eye Diseases; Female; Gastrointestinal Diseases; Humans; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Remission Induction; Survival Analysis; Treatment Outcome | 1996 |
Timed-sequential induction therapy improves postremission outcome in acute myeloid leukemia: a report from the Children's Cancer Group.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Diseases; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Humans; Infant; Infant, Newborn; Leukemia, Myeloid; Life Tables; Male; Prospective Studies; Remission Induction; Survival Analysis; Survival Rate; Thioguanine; Treatment Outcome | 1996 |
Amsacrine and continuous-infusion high-dose cytosine arabinoside as induction therapy for patients with newly-diagnosed acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Life Tables; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Remission Induction; Survival Analysis; Treatment Outcome; Vincristine | 1996 |
Dose intensification in acute myeloid leukaemia: greater effectiveness at lower cost. Principal report of the Medical Research Council's AML9 study. MRC Leukaemia in Adults Working Party.
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cost-Benefit Analysis; Cytarabine; Daunorubicin; Disease-Free Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Infant; Length of Stay; Leukemia, Myeloid; Middle Aged; Recurrence; Remission Induction; Risk Factors; Survival Analysis; Thioguanine | 1996 |
Peripheral blood stem cells mobilized from patients with acute myeloid leukaemia have different platelet repopulating abilities compared with those mobilized from patients with other diseases.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Blood Platelets; Bone Marrow; Cell Differentiation; Cell Lineage; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Hematopoietic Cell Growth Factors; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid; Lymphoma, Non-Hodgkin; Male; Megakaryocytes; Multiple Myeloma; Ovarian Neoplasms; Platelet Count; Thioguanine; Time Factors | 1996 |
Anthracycline drugs and MDR expression in human leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Aberrations; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Neoplasm Proteins; Neoplastic Stem Cells; Prognosis; Remission Induction; Survival Analysis; Treatment Outcome | 1996 |
A randomized investigation of high-dose versus standard-dose cytosine arabinoside with daunorubicin in patients with previously untreated acute myeloid leukemia: a Southwest Oncology Group study.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Remission Induction; Survival Analysis; Treatment Outcome | 1996 |
Timed sequential chemotherapy for advanced acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone | 1996 |
Allogeneic vs autologous stem cell transplantation vs chemotherapy in patients with acute myeloid leukemia in first remission: the BGMT 87 study.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Male; Middle Aged; Prospective Studies; Remission Induction | 1996 |
Long-term survival and development of secondary malignancies in patients with acute myeloid leukemia treated with aclarubicin or daunorubicin plus cytosine arabinoside followed by intensive consolidation chemotherapy in a Danish national phase III trial.
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Age Factors; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Middle Aged; Neoplasms, Second Primary; Recurrence; Remission Induction; Survival Rate; Survivors | 1997 |
Randomized comparison of DAT versus ADE as induction chemotherapy in children and younger adults with acute myeloid leukemia. Results of the Medical Research Council's 10th AML trial (MRC AML10). Adult and Childhood Leukaemia Working Parties of the Medica
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Humans; Hydrocortisone; Infant; Leukemia, Myeloid; Life Tables; Male; Methotrexate; Middle Aged; Myelodysplastic Syndromes; Patient Compliance; Remission Induction; Survival Analysis; Thioguanine; Treatment Outcome | 1997 |
Use of recombinant GM-CSF during and after remission induction chemotherapy in patients aged 61 years and older with acute myeloid leukemia: final report of AML-11, a phase III randomized study of the Leukemia Cooperative Group of European Organisation fo
Topics: Acute Disease; Aged; Aged, 80 and over; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Prospective Studies; Recombinant Proteins; Remission Induction | 1997 |
Comparison of autologous bone marrow transplantation and intensive chemotherapy as postremission therapy in adult acute myeloid leukemia. The Groupe Ouest Est Leucémies Aiguës Myéloblastiques (GOELAM).
Topics: Acute Disease; Adolescent; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Multivariate Analysis; Outcome Assessment, Health Care; Prognosis; Remission Induction | 1997 |
Long-term follow-up of three randomized trials comparing idarubicin and daunorubicin as induction therapies for patients with untreated acute myeloid leukemia.
Topics: Acute Disease; Adult; Antibiotics, Antineoplastic; Daunorubicin; Follow-Up Studies; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Survival Analysis; Treatment Outcome | 1997 |
Autologous peripheral blood stem cell transplantation for acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Leukocyte Count; Life Tables; Male; Middle Aged; Mitoxantrone; Neoplasm Recurrence, Local; Proportional Hazards Models; Prospective Studies; Remission Induction; Treatment Outcome | 1997 |
Mitoxantrone versus daunorubicin in induction-consolidation chemotherapy--the value of low-dose cytarabine for maintenance of remission, and an assessment of prognostic factors in acute myeloid leukemia in the elderly: final report. European Organization
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prognosis; Remission Induction; Survival Analysis | 1998 |
Intensified induction chemotherapy with high dose cytarabine and etoposide for acute myeloid leukemia: a review and updated results of the Australian Leukemia Study Group.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Etoposide; Humans; Leukemia, Myeloid; Remission Induction | 1998 |
Cost-effectiveness and quality-of-life assessment of GM-CSF as an adjunct to intensive remission induction chemotherapy in elderly patients with acute myeloid leukemia.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cost-Benefit Analysis; Cytarabine; Daunorubicin; Drug Costs; Female; Follow-Up Studies; Granulocyte-Macrophage Colony-Stimulating Factor; Hospital Costs; Humans; Karnofsky Performance Status; Length of Stay; Leukemia, Myeloid; Male; Middle Aged; Prospective Studies; Quality of Life; Remission Induction; Survival Analysis; Treatment Outcome | 1998 |
Quality of life in adult patients with acute myeloid leukemia receiving intensive and prolonged chemotherapy -- a longitudinal study.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Longitudinal Studies; Male; Middle Aged; Mitoxantrone; Quality of Life; Thioguanine | 1998 |
A double-blind placebo-controlled trial of granulocyte colony-stimulating factor in elderly patients with previously untreated acute myeloid leukemia: a Southwest oncology group study (9031).
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Double-Blind Method; Filgrastim; Granulocyte Colony-Stimulating Factor; Hospitalization; Humans; Infection Control; Leukemia, Myeloid; Life Tables; Middle Aged; Neutropenia; Recombinant Proteins; Remission Induction; Safety; Survival Analysis; Treatment Outcome | 1998 |
Marked improvements in outcome with chemotherapy alone in paediatric acute myeloid leukemia: results of the United Kingdom Medical Research Council's 10th AML trial. MRC Childhood Leukaemia Working Party.
Topics: Acute Disease; Adolescent; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Humans; Infant; Infant, Newborn; Leukemia, Myeloid; Male; Mitoxantrone; Patient Compliance; Recurrence; Remission Induction; Survival Rate; Thioguanine; Transplantation, Autologous; Transplantation, Homologous; Treatment Outcome | 1998 |
Repeated cycles of G-CSF-combined postremission chemotherapy for acute myeloid leukemia in a first complete remission: a pilot study.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Pilot Projects; Prednisolone; Recombinant Proteins; Time Factors; Vincristine | 1998 |
Frequency of prolonged remission duration after high-dose cytarabine intensification in acute myeloid leukemia varies by cytogenetic subtype.
Topics: Acute Disease; Adolescent; Adult; Analysis of Variance; Antimetabolites, Antineoplastic; Cohort Studies; Cytarabine; Daunorubicin; Female; Humans; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Prospective Studies; Remission Induction; Treatment Outcome | 1998 |
Multidrug resistance-associated protein in acute myeloid leukemia: No impact on treatment outcome.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow; Cell Line; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Multiple; Etoposide; Female; Humans; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Remission Induction; Survival Analysis; Time Factors; Treatment Outcome; Tumor Cells, Cultured | 1997 |
Impact of in vivo administration of interleukin 3 on proliferation, differentiation, and chemosensitivity of acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Bone Marrow; Cell Division; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Etoposide; Female; Hematopoietic Stem Cells; Humans; Immunophenotyping; Infusions, Intravenous; Interleukin-3; Ki-67 Antigen; Leukemia, Myeloid; Male; Middle Aged; Myelodysplastic Syndromes; Receptors, Growth Factor; Remission Induction | 1995 |
Estrogen receptor methylation is associated with improved survival in adult acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Bone Marrow Cells; Cytarabine; Daunorubicin; Disease-Free Survival; DNA Methylation; DNA, Neoplasm; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Neoplasm Proteins; Neoplastic Cells, Circulating; Neoplastic Stem Cells; Prognosis; Receptors, Estrogen; Regression Analysis | 1999 |
[Results of clinical trials in the treatment of acute myeloid leukemia in adults during a 7-year period].
Topics: Acute Disease; Adult; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Humans; Leukemia, Myeloid; Middle Aged; Time Factors; Treatment Outcome | 1999 |
No beneficial effect from addition of etoposide to daunorubicin, cytarabine, and 6-mercaptopurine in individualized induction therapy of adult acute myeloid leukemia: the JALSG-AML92 study. Japan Adult Leukemia Study Group.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Prospective Studies; Remission Induction; Survival Analysis | 1999 |
Phase I study of liposomal daunorubicin in patients with acute leukemia.
Topics: Acute Disease; Adult; Aged; Antibiotics, Antineoplastic; Daunorubicin; Dose-Response Relationship, Drug; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Liposomes; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence | 1999 |
Parallel phase I studies of daunorubicin given with cytarabine and etoposide with or without the multidrug resistance modulator PSC-833 in previously untreated patients 60 years of age or older with acute myeloid leukemia: results of cancer and leukemia g
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclosporins; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged | 1999 |
Prognostic value of p53 gene mutations and the product expression in de novo acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Amino Acid Substitution; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; DNA Mutational Analysis; Etoposide; Female; Gene Deletion; Genes, p53; Humans; Japan; Leukemia, Myeloid; Life Tables; Male; Mercaptopurine; Middle Aged; Mutation; Mutation, Missense; Neoplasm Proteins; Prednisolone; Prognosis; Regulatory Sequences, Nucleic Acid; Single-Blind Method; Survival Analysis; Tumor Suppressor Protein p53; Vincristine | 2000 |
Patients with de novo acute myeloid leukaemia and complex karyotype aberrations show a poor prognosis despite intensive treatment: a study of 90 patients.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Chromosome Aberrations; Cytarabine; Cytogenetic Analysis; Daunorubicin; Disease-Free Survival; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prognosis; Remission Induction; Thioguanine | 2001 |
Phase I/II study of the P-glycoprotein modulator PSC 833 in patients with acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Cyclosporins; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid; Male; Middle Aged; Risk Factors; Treatment Outcome | 2001 |
Comparison of 'sequential' versus 'standard' chemotherapy as re-induction treatment, with or without cyclosporine, in refractory/relapsed acute myeloid leukaemia (AML): results of the UK Medical Research Council AML-R trial.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cyclosporine; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Humans; Immunosuppressive Agents; Leukemia, Myeloid; Male; Middle Aged; Remission Induction | 2001 |
Attempts to improve treatment outcomes in acute myeloid leukemia (AML) in older patients: the results of the United Kingdom Medical Research Council AML11 trial.
Topics: Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Granulocyte Colony-Stimulating Factor; Humans; Immunologic Factors; Interferon-alpha; Lenograstim; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prednisone; Recombinant Proteins; Remission Induction; Survival Analysis; Thioguanine; Treatment Outcome; United Kingdom; Vincristine | 2001 |
The predictive value of hierarchical cytogenetic classification in older adults with acute myeloid leukemia (AML): analysis of 1065 patients entered into the United Kingdom Medical Research Council AML11 trial.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Etoposide; Female; Follow-Up Studies; Granulocyte Colony-Stimulating Factor; Humans; Immunologic Factors; Interferon-alpha; Karyotyping; Lenograstim; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Predictive Value of Tests; Prednisone; Prognosis; Recombinant Proteins; Remission Induction; Survival Analysis; Thioguanine; Treatment Outcome; United Kingdom; Vincristine | 2001 |
Prognostic significance of the null genotype of glutathione S-transferase-T1 in patients with acute myeloid leukemia: increased early death after chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Follow-Up Studies; Gene Deletion; Genotype; Glutathione Transferase; Humans; Isoenzymes; Leukemia, Myeloid; Mercaptopurine; Multivariate Analysis; NAD(P)H Dehydrogenase (Quinone); Neoplasm Proteins; Peroxidase; Polymorphism, Genetic; Prednisolone; Prognosis; Remission Induction; Survival Analysis; Treatment Outcome | 2002 |
Dose-finding study of valspodar (PSC 833) with daunorubicin and cytarabine to reverse multidrug resistance in elderly patients with previously untreated acute myeloid leukemia.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cohort Studies; Cyclosporins; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Edema; Female; Fever; Humans; Hypokalemia; Leukemia, Myeloid; Male; Maximum Tolerated Dose; Middle Aged; Nausea; Neoplasm Proteins; Remission Induction; Survival Analysis; Survival Rate; Treatment Outcome | 2000 |
Effect of early splenectomy and cyclic acute leukemia-like chemotherapy on the course of chronic myeloid leukemia.
Topics: Adult; Aged; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Prednisone; Splenectomy; Thioguanine; Vincristine | 1978 |
The immunotherapy of acute myelogenous leukaemia using intravenous BCG.
Topics: Acute Disease; Adolescent; Adult; Aged; BCG Vaccine; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Injections, Intravenous; Leukemia, Myeloid; Middle Aged; Remission, Spontaneous; Skin Tests | 1977 |
Acute myelocytic leukemia.
Topics: Animals; BCG Vaccine; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Immunotherapy; Leukemia L1210; Leukemia, Myeloid; Mercaptopurine; Mice; Mycobacterium bovis; Neuraminidase; Thioguanine | 1976 |
Chronic myelogenous leukemia: a clinical and experimental evaluation of splenectomy and intensive chemotherapy.
Topics: Adult; Antineoplastic Agents; Busulfan; Chromosome Aberrations; Chromosomes, Human, 21-22 and Y; Clinical Trials as Topic; Cytarabine; Daunorubicin; Drug Evaluation; Drug Therapy, Combination; Evaluation Studies as Topic; Female; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Middle Aged; Splenectomy; Thioguanine | 1975 |
Cell kinetics in leukemia. Correlation with clinical features and response to chemotherapy.
Topics: Bone Marrow; Bone Marrow Cells; Cytarabine; Daunorubicin; DNA, Neoplasm; Drug Therapy, Combination; Humans; Kinetics; Leucovorin; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Mitotic Index; Thioguanine | 1975 |
Intensive induction chemotherapy in elderly patients. The BGMT Group.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged | 1992 |
High-dose cytosine arabinoside remission induction for acute myelogenous leukemia: comparison of two regimens of remission maintenance.
Topics: Acute Disease; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid; Middle Aged; Prednisone; Survival Analysis; Tretinoin | 1992 |
[The therapeutic results in acute myeloid leukemias in elderly patients].
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Resistance; Female; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Remission Induction; Time Factors | 1992 |
Varying intensity of postremission therapy in acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Follow-Up Studies; Heparin; Humans; Leukemia, Myeloid; Middle Aged; Remission Induction; Thioguanine | 1992 |
Autologous bone marrow transplantation vs intensive chemotherapy in first complete remission: interim results of GOELAM study in AML.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Drug Administration Schedule; France; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Remission Induction; Survival Analysis; Transplantation, Autologous | 1992 |
The impact of early intensive therapy on event-free survival (EFS) in children with acute myeloid leukemia (AML).
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Infant; Leukemia, Myeloid; Prognosis; Remission Induction; Survival Rate; Thioguanine | 1992 |
Therapeutic strategies for postremission treatment in childhood acute myeloid leukemia (AML). The AIEOP experience 1987-1991.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Daunorubicin; Female; Humans; Infant; Italy; Leukemia, Myeloid; Male; Pilot Projects; Random Allocation; Recurrence; Remission Induction | 1992 |
Intensive chemotherapy with or without additional bone marrow transplantation in paediatric AML: progress report on the MRC AML 10 trial. Medical Research Council Working Party on Childhood Leukaemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Humans; Infant; Leukemia, Myeloid; Recurrence; Remission Induction; Thioguanine; United Kingdom | 1992 |
Intensive post-remission therapy with Ara-C in adults with acute myeloid leukemia: initial results of a CALGB phase III trial. The Cancer and Leukemia Group B.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Remission Induction | 1992 |
Longterm effects of prolonged maintenance and of very early intensification chemotherapy in AML: data from AMLCG.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Leukemia, Myeloid; Middle Aged; Recurrence; Remission Induction; Thioguanine | 1992 |
Intensive consolidation chemotherapy versus standard consolidation maintenance in acute myelogenous leukemia (AML) in first remission. An EORTC/GIMEMA phase III trial (AML8 B). The EORTC Leukemia Cooperative Group and the GIMEMA Group.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Drug Administration Schedule; Follow-Up Studies; Humans; Italy; Leukemia, Myeloid; Middle Aged; Remission Induction; Thioguanine | 1992 |
Randomized study of individualized induction therapy with or without VCR, and of maintenance of 4 or 12 courses in adult AML: JALSG-AML87. Japan Adult Leukemia Study Group (JALSG).
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Humans; Japan; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Prednisolone; Remission Induction; Vincristine | 1992 |
Improved cure rate by very early intensification combined with prolonged maintenance chemotherapy in patients with acute myeloid leukemia: data from the AML Cooperative Group.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid; Remission Induction; Thioguanine | 1991 |
Double intensive consolidation chemotherapy in adult acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Child; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Survival Analysis | 1991 |
New agents in the treatment of acute myeloid leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Cytarabine; Daunorubicin; Drug Evaluation; Etoposide; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Remission Induction; Tretinoin | 1991 |
In vitro and in vivo effects of rh GM-CSF in acute myeloid leukemia (AML).
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Division; Cytarabine; Daunorubicin; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Infusions, Intravenous; Leukemia, Myeloid; Mitoxantrone; Recombinant Proteins; Thioguanine; Tumor Stem Cell Assay | 1991 |
A comparative study of two different doses of cytarabine for acute myeloid leukemia: a phase III trial of Cancer and Leukemia Group B.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Middle Aged; Prednisone; Remission Induction; Thioguanine; Time Factors; Vincristine | 1991 |
Value of maintenance therapy with chemotherapy or interferon during remission of acute myeloid leukaemia.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Interferon-alpha; Leukemia, Myeloid; Male; Prospective Studies; Remission Induction; Thioguanine | 1991 |
Acute myeloid leukaemia: results of the New Zealand AML-1 study. The Leukaemia Study Group of the New Zealand Society for Haematology.
Topics: Acute Disease; Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Middle Aged; New Zealand; Remission Induction; Survival Rate | 1991 |
Mitoxantrone and cytarabine versus daunorubicin and cytarabine in previously untreated patients with acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prospective Studies; Remission Induction | 1991 |
Double intensive consolidation chemotherapy in adult acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Amsacrine; Analysis of Variance; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Pilot Projects; Proportional Hazards Models; Remission Induction | 1991 |
A randomized clinical trial of daunorubicin and a combination of prednisone, vincristine, 6-mercaptopurine, and methotrexate in adult acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Antineoplastic Agents; Clinical Trials as Topic; Daunorubicin; Female; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Prospective Studies; Remission, Spontaneous; Time Factors; Vincristine | 1972 |
Daunorubicin and adriamycin in the treatment of leukemia.
Topics: Adult; Anemia, Aplastic; Arrhythmias, Cardiac; Blood Platelets; Clinical Trials as Topic; Daunorubicin; Doxorubicin; Evaluation Studies as Topic; Female; Hemorrhagic Disorders; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocyte Count; Leukopenia; Male; Remission, Spontaneous; Thrombocytopenia | 1973 |
313 other study(ies) available for daunorubicin and Granulocytic Leukemia
| Article | Year |
|---|---|
Hexokinase II inhibition by 3-bromopyruvate sensitizes myeloid leukemic cells K-562 to anti-leukemic drug, daunorubicin.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Daunorubicin; DNA Damage; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression Regulation, Neoplastic; Glucose; Hexokinase; Humans; Leukemia, Myeloid; Mitochondria; Pyruvates; Reactive Oxygen Species | 2019 |
Acute myeloid leukemia in first remission: to choose transplantation or not?
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Decision Making; Female; Humans; Leukemia, Myeloid; Nucleophosmin; Patient Preference; Remission Induction; Review Literature as Topic; Stem Cell Transplantation; Transplantation, Homologous | 2013 |
The clinical characteristics and prognostic significance of MN1 gene and MN1-associated microRNA expression in adult patients with de novo acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Gene Expression Regulation, Leukemic; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Leukemia, Myeloid; Male; MicroRNAs; Middle Aged; Neoplasm Proteins; Nucleophosmin; Peripheral Blood Stem Cell Transplantation; Prognosis; Real-Time Polymerase Chain Reaction; RNA, Neoplasm; Survival Analysis; Trans-Activators; Transplantation, Autologous; Treatment Outcome; Tumor Suppressor Proteins; Vidarabine; Young Adult | 2013 |
Idarubicin appears equivalent to dose-intense daunorubicin for remission induction in patients with acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Daunorubicin; Dose-Response Relationship, Drug; Female; Humans; Idarubicin; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Middle Aged; Outcome Assessment, Health Care; Remission Induction; Young Adult | 2013 |
Efficacy of RNA polymerase II inhibitors in targeting dormant leukaemia cells.
Topics: Acute Disease; Adenine Nucleotides; Antineoplastic Agents; Apoptosis; Arabinonucleosides; Azacitidine; Cell Line, Tumor; Cell Survival; Clofarabine; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Flavonoids; Heterocyclic Compounds, 4 or More Rings; Humans; Leukemia, Myeloid; Piperidines; Purines; RNA Polymerase II; RNA, Neoplasm; Roscovitine; Sirolimus; TOR Serine-Threonine Kinases | 2013 |
Nano-hole induction by nanodiamond and nanoplatinum liquid, DPV576, reverses multidrug resistance in human myeloid leukemia (HL60/AR).
Topics: Cell Line, Tumor; Cell Membrane; Cell Survival; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid; Microscopy, Atomic Force; Nanodiamonds; Nanomedicine; Platinum | 2013 |
Higher daunorubicin exposure benefits FLT3 mutated acute myeloid leukemia.
Topics: Acute Disease; Antibiotics, Antineoplastic; Daunorubicin; Dose-Response Relationship, Drug; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid; Mutation; Outcome Assessment, Health Care; Survival Analysis; Tandem Repeat Sequences | 2016 |
[High risk of cardiac dysfunction after treatment of secondary acute myeloid leukemia following chemotherapy and radiotherapy for breast cancer].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Daunorubicin; Epirubicin; Female; Fluorouracil; Heart Diseases; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Middle Aged; Neoplasms, Second Primary; Remission Induction; Stroke Volume | 2010 |
CRIM1 is expressed at higher levels in drug-resistant than in drug-sensitive myeloid leukemia HL60 cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Morphogenetic Protein 4; Bone Morphogenetic Protein 7; Bone Morphogenetic Protein Receptors; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluorescent Antibody Technique; HL-60 Cells; Humans; Leukemia, Myeloid; Membrane Proteins; RNA, Messenger; Smad5 Protein | 2010 |
Simultaneous acute myeloid leukaemia and de novo acute hepatitis B: a novel management strategy.
Topics: Acute Disease; Antineoplastic Agents; Antiviral Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Guanine; Hepatitis B; Humans; Leukemia, Myeloid; Treatment Outcome; Young Adult | 2011 |
Liposomal encapsulation of a synergistic molar ratio of cytarabine and daunorubicin enhances selective toxicity for acute myeloid leukemia progenitors as compared to analogous normal hematopoietic cells.
Topics: Acute Disease; Bone Marrow Cells; Cell Proliferation; Cell Survival; Cells, Cultured; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Drug Combinations; Drug Compounding; Drug Synergism; Flow Cytometry; Humans; Leukemia, Myeloid; Leukocytes, Mononuclear; Liposomes; Stem Cells; Tumor Cells, Cultured | 2011 |
Autophagy inhibition enhances daunorubicin-induced apoptosis in K562 cells.
Topics: Antibiotics, Antineoplastic; Antirheumatic Agents; Apoptosis; Autophagy; Chloroquine; Daunorubicin; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Humans; K562 Cells; Leukemia, Myeloid; Microscopy, Confocal; Microscopy, Electron, Transmission; Neoplasms; RNA, Small Interfering; Signal Transduction | 2011 |
Feasibility of outpatient consolidation chemotherapy in older versus younger patients with acute myeloid leukemia.
Topics: Acute Disease; Adult; Age Factors; Aged; Aged, 80 and over; Ambulatory Care; Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Etoposide; Feasibility Studies; Female; Humans; Infections; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neutropenia; Outpatients; Patient Readmission | 2012 |
Induction chemotherapy versus palliative treatment for acute myeloid leukemia in a consecutive cohort of elderly patients.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Blood Component Transfusion; Chromosome Aberrations; Cohort Studies; Comorbidity; Cytarabine; Daunorubicin; Etoposide; Female; Follow-Up Studies; Humans; Hydroxyurea; Immunophenotyping; Kaplan-Meier Estimate; Karyotyping; Leukemia, Myeloid; Male; Palliative Care; Remission Induction; Retrospective Studies; Serbia; Treatment Outcome | 2012 |
Influence of obesity on efficacy and toxicity of induction chemotherapy in patients with newly diagnosed acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Body Mass Index; Cytarabine; Daunorubicin; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Fever; Humans; Idarubicin; Induction Chemotherapy; Leukemia, Myeloid; Male; Middle Aged; Multivariate Analysis; Neutropenia; Obesity; Outcome Assessment, Health Care; Prognosis; Remission Induction; Young Adult | 2013 |
Iodinin (1,6-dihydroxyphenazine 5,10-dioxide) from Streptosporangium sp. induces apoptosis selectively in myeloid leukemia cell lines and patient cells.
Topics: Actinobacteria; Adolescent; Adult; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Daunorubicin; Female; Gene Expression Regulation, Bacterial; Humans; Leukemia, Myeloid; Male; Middle Aged; Models, Molecular; Molecular Structure; Phenazines; Rats; Young Adult | 2013 |
Influence of ceramide metabolism on P-glycoprotein function in immature acute myeloid leukemia KG1a cells.
Topics: Acute Disease; Antigens, CD; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Ceramides; Daunorubicin; Drug Interactions; Gangliosides; Glucosylceramides; Humans; Lactosylceramides; Leukemia, Myeloid; Morpholines; Phosphorylation; Sphingosine; Tumor Cells, Cultured; Vincristine | 2002 |
SAB--a promising new treatment to improve remission rates in AML in the elderly?
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Humans; Leukemia, Myeloid; Remission Induction; Thioguanine | 2002 |
CD7+ and CD56+ myeloid/natural killer cell precursor acute leukemia treated with idarubicin and cytosine arabinoside.
Topics: Acute Disease; Aged; Antigens, CD; Antigens, CD7; Antigens, Differentiation, Myelomonocytic; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; CD56 Antigen; Cytarabine; Daunorubicin; Diagnosis, Differential; Etoposide; Fatal Outcome; Humans; Idarubicin; Killer Cells, Natural; Leukemia, Myeloid; Leukemic Infiltration; Lymphoma, Non-Hodgkin; Male; Mercaptopurine; Mitoxantrone; Myeloid Cells; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Sarcoma, Myeloid; Sialic Acid Binding Ig-like Lectin 3 | 2002 |
Anti-angiogenic activity of the purine analog 6-thioguanine.
Topics: 2-Aminopurine; Acute Disease; Aged; Allantois; Anemia; Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cattle; Cell Line, Transformed; Chick Embryo; Chorion; Cytarabine; Daunorubicin; Drug Evaluation; Endothelial Growth Factors; Endothelium, Vascular; Etoposide; Female; Fibroblast Growth Factor 2; Follow-Up Studies; Humans; Leukemia, Myeloid; Lymphokines; Male; Mice; Mice, Inbred BALB C; Middle Aged; Neovascularization, Pathologic; Neovascularization, Physiologic; Remission Induction; Stress, Mechanical; Thioguanine; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2002 |
Liposomal daunorubicin (DaunoXome) for treatment of relapsed meningeal acute myeloid leukemia.
Topics: Acute Disease; Adult; Antibiotics, Antineoplastic; Daunorubicin; Drug Carriers; Female; Humans; Leukemia, Myeloid; Liposomes; Male; Meningeal Neoplasms; Neoplasm Recurrence, Local | 2002 |
PK11195, an isoquinoline carboxamide ligand of the mitochondrial benzodiazepine receptor, increased drug uptake and facilitated drug-induced apoptosis in human multidrug-resistant leukemia cells in vitro.
Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carcinoma; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Female; Fluoresceins; Fluorescent Dyes; HL-60 Cells; Humans; Isoquinolines; Leukemia, Myeloid; Ligands; Mitochondrial Proteins; Ovarian Neoplasms; Receptors, GABA-A; Tumor Cells, Cultured | 2002 |
Immunophenotypic evidence of leukemia after induction therapy predicts relapse: results from a prospective Children's Cancer Group study of 252 patients with acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Antigens, CD; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Bone Marrow Examination; California; Child; Child, Preschool; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Female; Flow Cytometry; Granulocyte Colony-Stimulating Factor; Humans; Idarubicin; Immunophenotyping; Infant; Leukemia, Myeloid; Male; Multicenter Studies as Topic; Myelodysplastic Syndromes; Neoplasm, Residual; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic; Recurrence; Remission Induction; Risk Factors; Single-Blind Method; Survival Analysis; Thioguanine; Treatment Outcome | 2003 |
Cholesterol-modulating agents kill acute myeloid leukemia cells and sensitize them to therapeutics by blocking adaptive cholesterol responses.
Topics: Acute Disease; Antineoplastic Agents; Bone Marrow Cells; Bridged Bicyclo Compounds, Heterocyclic; Cholesterol; Cytarabine; Daunorubicin; Drug Synergism; HL-60 Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leukemia, Myeloid; Lipoproteins, LDL; Lovastatin; Membrane Lipids; Protein Prenylation; Protein Processing, Post-Translational; Radiation-Sensitizing Agents; Tricarboxylic Acids; Tumor Cells, Cultured | 2003 |
Different effects of metabolic inhibitors and cyclosporin A on daunorubicin transport in leukemia cells from patients with AML.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cyclosporine; Daunorubicin; Enzyme Inhibitors; Female; Humans; Iodoacetates; Leukemia, Myeloid; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; RNA, Messenger; Sodium Azide; Vault Ribonucleoprotein Particles | 2003 |
RNA interference is a functional pathway with therapeutic potential in human myeloid leukemia cell lines.
Topics: Antineoplastic Agents, Phytogenic; Cell Death; Cell Differentiation; Daunorubicin; Etoposide; Gene Expression Regulation, Neoplastic; Genetic Therapy; HL-60 Cells; Humans; Leukemia, Myeloid; Oligodeoxyribonucleotides, Antisense; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-raf; RNA Interference; RNA, Double-Stranded; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2003 |
New designs for phase 2 clinical trials.
Topics: Acute Disease; Adenine Nucleotides; Adult; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Arabinonucleosides; Bayes Theorem; Bias; Biomarkers; Clinical Trials, Phase II as Topic; Clofarabine; Confounding Factors, Epidemiologic; Cytarabine; Daunorubicin; Drug Carriers; False Negative Reactions; Follow-Up Studies; Humans; Idarubicin; Leukemia, Myeloid; Liposomes; Middle Aged; Patient Selection; Randomized Controlled Trials as Topic; Remission Induction; Research Design; Thalidomide; Topotecan; Treatment Outcome | 2003 |
Maternal and fetal outcomes in pregnancy complicated with acute leukemia: a single institutional experience with 10 pregnancies at 16 years.
Topics: Abortion, Spontaneous; Abortion, Therapeutic; Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Fatal Outcome; Female; Fetal Death; Follow-Up Studies; Gestational Age; Humans; Infant, Newborn; Leukemia, Myeloid; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pregnancy; Pregnancy Complications, Neoplastic; Pregnancy Outcome; Retrospective Studies; Turkey | 2003 |
Reversal of P-glycoprotein-mediated multidrug resistance by protopanaxatriol ginsenosides from Korean red ginseng.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Flow Cytometry; Ginsenosides; Humans; Leukemia, Myeloid; Panax; Phytotherapy; Plant Preparations; Sapogenins; Triterpenes; Tumor Cells, Cultured | 2003 |
Immunophenotyping is an independent factor for risk stratification in AML.
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Cytarabine; Daunorubicin; Female; Humans; Immunophenotyping; Leukemia, Myeloid; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Prognosis; Retrospective Studies; Risk Factors; Survival Analysis | 2003 |
Autologous peripheral blood stem cell transplantation in first remission adult acute myeloid leukaemia--an intention to treat analysis and comparison of outcome using a predictive model based on the MRC AML10 cohort.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Clinical Trials as Topic; Cohort Studies; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Mobilization; Humans; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Models, Biological; Peripheral Blood Stem Cell Transplantation; Remission Induction; Risk; Survival Analysis; Thioguanine; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome | 2003 |
Comparison of fludarabine-containing salvage chemotherapy regimens for relapsed/refractory acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Leukemia, Myeloid; Middle Aged; Neoplasm Recurrence, Local; Remission Induction; Salvage Therapy; Treatment Outcome; Vidarabine | 2003 |
Cytotoxic drugs enhance the ex vivo sensitivity of malignant cells from a subset of acute myeloid leukaemia patients to apoptosis induction by tumour necrosis factor receptor-related apoptosis-inducing ligand.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Caspase 3; Caspases; Cytarabine; Daunorubicin; Drug Interactions; Humans; Leukemia, Myeloid; Membrane Glycoproteins; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Vidarabine | 2003 |
In vitro antileukemic effect of a new anthracycline analogue, MEN 11079.
Topics: Acute Disease; Adult; Aged; Annexin A5; Anthracyclines; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Cycle; Daunorubicin; Female; Humans; Idarubicin; K562 Cells; Leukemia, Myeloid; Leukocytes, Mononuclear; Male; Middle Aged; Propidium; Reverse Transcriptase Polymerase Chain Reaction | 2003 |
[A NEW ANTIBIOTIC WITH CYTOSTATIC PROPERTIES: RUBIDOMYCIN].
Topics: Adenocarcinoma; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Benzopyrenes; Carcinoma, Ehrlich Tumor; Daunorubicin; Leukemia; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Mammary Neoplasms, Animal; Mammary Neoplasms, Experimental; Mice; Neoplasms; Research; Sarcoma 180; Sarcoma, Experimental; Streptomyces; Toxicology | 1963 |
Chemotherapy increases transgene expression in leukemic cells.
Topics: Acute Disease; Animals; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Gene Expression; Genetic Therapy; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Lac Operon; Leukemia, Myeloid; Mice; Neoplasm Transplantation; Transfection; Transgenes; Tumor Cells, Cultured | 2003 |
Prognostic relevance of immunophenotyping in 379 patients with acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Cytogenetics; Daunorubicin; DNA Nucleotidylexotransferase; Female; Humans; Immunophenotyping; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Remission Induction; Survival Rate | 2004 |
Low L-selectin (CD62L) expression in acute myeloid leukemia correlates with a bad cytogenetic risk.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Chromosome Aberrations; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; L-Selectin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplasm Proteins; Neoplastic Stem Cells; Remission Induction; Risk; Thioguanine; Treatment Outcome; Tretinoin | 2003 |
The interaction of daunorubicin and mitoxantrone with the red blood cells of acute myeloid leukemia patients.
Topics: Acute Disease; Adult; Aged; Daunorubicin; Electron Spin Resonance Spectroscopy; Erythrocyte Membrane; Erythrocytes; Humans; Leukemia, Myeloid; Lipid Bilayers; Membrane Fluidity; Middle Aged; Mitoxantrone | 2003 |
Cytoprotective effect of glucosylceramide synthase inhibition against daunorubicin-induced apoptosis in human leukemic cell lines.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Glucosyltransferases; Glycosylation; HL-60 Cells; Humans; Leukemia, Myeloid; Morpholines; Protective Agents; U937 Cells | 2004 |
P-glycoprotein (Pgp) modulation in untreated acute myeloid leukemia (AML): Cancer and Leukemia Group B (CALGB) trials in younger and older adults.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Clinical Trials, Phase I as Topic; Clinical Trials, Phase III as Topic; Cytarabine; Daunorubicin; Etoposide; Humans; Leukemia, Myeloid; Middle Aged; Treatment Outcome | 2004 |
Prognostic impact of early response to induction therapy as assessed by multiparameter flow cytometry in acute myeloid leukemia.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Cytarabine; Daunorubicin; Female; Flow Cytometry; Humans; Immunophenotyping; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplasm, Residual; Prognosis; Remission Induction; Stem Cell Transplantation; Survival Analysis; Thioguanine | 2004 |
A G-quadruplex-interactive agent, telomestatin (SOT-095), induces telomere shortening with apoptosis and enhances chemosensitivity in acute myeloid leukemia.
Topics: Acute Disease; Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Apoptosis; Cytarabine; Daunorubicin; DNA-Binding Proteins; Drug Resistance, Neoplasm; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Oxazoles; Telomerase; Telomere; U937 Cells | 2004 |
Treating childhood acute myeloid leukaemia with the AML-BFM-83 protocol: experience in a developing country.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Developing Countries; Disease-Free Survival; Etoposide; Female; Humans; Infant; Infant, Newborn; Leukemia, Myeloid; Malaysia; Male; Treatment Outcome | 2004 |
Breast cancer resistance protein and P-glycoprotein in 149 adult acute myeloid leukemias.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Proliferation; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Expression Regulation, Leukemic; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Neoplasm Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Survival Rate | 2004 |
Disease biology rather than age is the most important determinant of survival of patients > or = 60 years with acute myeloid leukemia treated with uniform intensive therapy.
Topics: Acute Disease; Age Factors; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Follow-Up Studies; Hematologic Diseases; Humans; Karyotyping; L-Lactate Dehydrogenase; Leukemia, Myeloid; Leukocyte Count; Male; Middle Aged; Myelodysplastic Syndromes; Remission Induction; Retrospective Studies; Survival Rate; Treatment Outcome | 2005 |
Limited value of FLT3 mRNA expression in the bone marrow for prognosis and monitoring of patients with acute myeloid leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bone Marrow; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; fms-Like Tyrosine Kinase 3; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Male; Middle Aged; Neoplasm Proteins; Neoplasm, Residual; Prognosis; Remission Induction; RNA, Messenger; RNA, Neoplasm; Survival Analysis; Tretinoin | 2005 |
Prognostic factors and outcome of core binding factor acute myeloid leukemia patients with t(8;21) differ from those of patients with inv(16): a Cancer and Leukemia Group B study.
Topics: Acute Disease; Aged; Antineoplastic Combined Chemotherapy Protocols; Aziridines; Benzoquinones; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Prognosis; Proportional Hazards Models; Prospective Studies; Remission Induction; Statistics, Nonparametric; Survival Analysis | 2005 |
Chemotherapy for acute myeloid leukemias with cytosine arabinoside, daunorubicin, etoposide, and mitoxantrone may cause permanent oligoasthenozoospermia or amenorrhea in middle-aged patients.
Topics: Acute Disease; Adult; Amenorrhea; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Oligospermia; Sperm Motility; Spermatozoa | 2005 |
Acute myeloid leukemia treatment in patients over 60 years of age. Comparison of symptomatic, palliative, and aggressive therapy.
Topics: Acute Disease; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Hematopoietic Stem Cell Transplantation; Hospitalization; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Palliative Care; Prognosis; Remission Induction; Retrospective Studies; Survival Analysis; Treatment Outcome | 2005 |
T-cell acute lymphoblastic leukemia relapsing as acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Antigens, CD7; Antigens, Differentiation, T-Lymphocyte; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Bone Marrow; Cell Differentiation; Cell Lineage; Core Binding Factor Alpha 2 Subunit; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Diagnosis, Differential; Doxorubicin; Etoposide; Fatal Outcome; Female; Gene Dosage; Histone-Lysine N-Methyltransferase; Humans; Immunophenotyping; Karyotyping; Leukemia-Lymphoma, Adult T-Cell; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Myeloid-Lymphoid Leukemia Protein; Neoplasms, Second Primary; Neoplastic Stem Cells; Proto-Oncogenes; Recurrence; T-Lymphocyte Subsets; Vincristine | 2007 |
Improved outcome in childhood acute myeloid leukemia in Singapore with the MRC AML 10 protocol.
Topics: Acute Disease; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; Cytarabine; Daunorubicin; Developing Countries; Disease-Free Survival; Drug Evaluation; Etoposide; Female; Gastrointestinal Diseases; Heart Diseases; Hematologic Diseases; Humans; Infant; Infections; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Mitoxantrone; Prednisone; Remission Induction; Retrospective Studies; Singapore; Survival Analysis; Thioguanine; Treatment Outcome; Vincristine | 2007 |
Prognostic significance of WT1 gene expression in pediatric acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Combined Chemotherapy Protocols; Brazil; Child; Child, Preschool; Chromosome Inversion; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytarabine; Daunorubicin; Etoposide; Female; Follow-Up Studies; Gene Expression Regulation, Leukemic; Genes, Wilms Tumor; Humans; Infant; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Male; Neoplasm Proteins; Prognosis; Proportional Hazards Models; Reverse Transcriptase Polymerase Chain Reaction; Survival Analysis; Translocation, Genetic; WT1 Proteins | 2007 |
The 4'-O-benzylated doxorubicin analog WP744 overcomes resistance mediated by P-glycoprotein, multidrug resistance protein and breast cancer resistance protein in cell lines and acute myeloid leukemia cells.
Topics: Adult; Aged; Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line, Tumor; Cell Survival; Daunorubicin; Doxorubicin; Drug Resistance, Neoplasm; Female; Fluorescence; Humans; Leukemia, Myeloid; Male; Middle Aged; Neoplasm Proteins | 2007 |
Expression of multidrug resistance (MDR) proteins and in vitro drug resistance in acute leukemias.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Cell Survival; Child; Child, Preschool; Coloring Agents; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Infant; Inhibitory Concentration 50; Leukemia; Leukemia, Myeloid; Male; Methylphenazonium Methosulfate; Middle Aged; Neoplasm Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Recurrence; Staining and Labeling; Tetrazolium Salts; Thiazoles; Treatment Outcome; Tumor Cells, Cultured | 2007 |
Monitoring of minimal residual disease in adult acute myeloid leukemia using peripheral blood as an alternative source to bone marrow.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; Bone Marrow Examination; Cytarabine; Daunorubicin; Disease-Free Survival; Etoposide; Female; Flow Cytometry; Humans; Idarubicin; Kaplan-Meier Estimate; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplasm, Residual; Organ Specificity; Randomized Controlled Trials as Topic; Remission Induction; Survival Analysis; Treatment Outcome | 2007 |
Topoisomerase IIalpha mRNA and protein expression vs. in vitro drug resistance and clinical outcome in acute leukaemia.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antigens, Neoplasm; Blood Cells; Bone Marrow Cells; Cell Survival; Daunorubicin; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Prognosis; RNA, Messenger | 2007 |
The criteria for bone marrow recovery post-myelosuppressive therapy for acute myelogenous leukemia: a quantitative study.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Blood Cell Count; Bone Marrow; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Female; Humans; Image Processing, Computer-Assisted; Immunophenotyping; Leukemia, Myeloid; Male; Middle Aged; Recovery of Function; Remission Induction; Time Factors | 2007 |
The role of the proto-oncogene ETS2 in acute megakaryocytic leukemia biology and therapy.
Topics: Acute Disease; Cell Differentiation; Child; Chromosomes, Human, Pair 21; Cytarabine; Daunorubicin; Down Syndrome; Drug Resistance, Neoplasm; Erythroid Precursor Cells; Erythropoiesis; GATA1 Transcription Factor; Gene Dosage; Gene Expression Regulation, Leukemic; Genetic Predisposition to Disease; Humans; K562 Cells; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid; Megakaryocytes; Neoplasm Proteins; Proto-Oncogene Mas; Proto-Oncogene Protein c-ets-2; Thrombopoiesis | 2008 |
Cardiomyopathy in children with Down syndrome treated for acute myeloid leukemia: a report from the Children's Oncology Group Study POG 9421.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cardiomyopathies; Child, Preschool; Daunorubicin; Disease-Free Survival; Down Syndrome; Female; Heart; Humans; Leukemia, Myeloid; Male; Mitoxantrone; Prospective Studies; Remission Induction; Retrospective Studies; Treatment Outcome | 2008 |
Clustering of endocytic organelles in parental and drug-resistant myeloid leukaemia cell lines lacking centrosomally organised microtubule arrays.
Topics: Cell Line, Tumor; Centrosome; Daunorubicin; Doxorubicin; Drug Resistance, Neoplasm; Endocytosis; Endosomes; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Leukemia, Myeloid; Lysosomes; Microtubules; Models, Biological; Organelles; Protein Transport; Subcellular Fractions; Transferrin | 2008 |
[Acute non-lymphatic leukemia after treatment of Hodgkin's lymphoma with chemotherapy and radiotherapy].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Cytarabine; Dacarbazine; Daunorubicin; Doxorubicin; Hodgkin Disease; Humans; Leukemia, Myeloid; Leukemia, Radiation-Induced; Male; Mechlorethamine; Prednisone; Procarbazine; Radiotherapy; Thioguanine; Vinblastine; Vincristine | 1984 |
Histomorphologic study of bone marrow in acute leukemia following chemotherapy and autologous bone marrow transplantation.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Bone Marrow; Bone Marrow Transplantation; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Thioguanine; Time Factors; Transplantation, Autologous; Vincristine; Whole-Body Irradiation | 1983 |
[The Münster study of intensive induction and consolidation therapy without maintenance therapy of acute myeloid leukemia. Results of 93 patients--cellular determinants for response and length of remission].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Blood Platelets; Cytarabine; Daunorubicin; Germany, West; Humans; L-Lactate Dehydrogenase; Leukemia, Myeloid; Middle Aged; Thioguanine; Time Factors | 1983 |
[Comparison of the therapeutic efficacity of 2 induction protocols in acute myeloid leukemia using exact quantification of bone marrow cellularity].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Count; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid; Thioguanine | 1983 |
[Results of treatment of acute myeloid leukemia in adults].
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Male; Middle Aged | 1983 |
Autologous marrow transplantation for patients with chronic myelogenous leukemia (CML) in blast crisis.
Topics: Adult; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Doxorubicin; Female; Freezing; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Melphalan; Middle Aged; Teniposide; Thioguanine; Tissue Preservation; Transplantation, Autologous | 1984 |
Latent period of 9 years in the presentation of a myeloproliferative disorder.
Topics: Adult; Bone Marrow; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Mercaptopurine; Skin Manifestations; Time Factors | 1983 |
Urinary excretion of beta-aminoisobutyrate and pseudouridine in acute and chronic myeloid leukemia.
Topics: Adult; Aminoisobutyric Acids; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocyte Count; Male; Middle Aged; Pseudouridine; Uridine | 1983 |
[Clinical studies of BH-AC-DMP in adult acute nonlymphocytic leukemia].
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone | 1983 |
Diffusion chamber cultures of bone marrow cells in refractory anemia with excess oil blasts (RAEB).
Topics: Anemia, Aplastic; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid; Methylprednisolone; Thioguanine | 1981 |
Tumour lysis syndrome with hypocälcaemia in accelerated chronic granulocytic leukaemia.
Topics: Adult; Cell Transformation, Neoplastic; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Hypocalcemia; Leukemia, Myeloid; Prednisone; Syndrome; Time Factors; Vincristine | 1982 |
Cell proliferation in acute promyelocytic leukemia. Studies with thymidine labeling and in vitro colony assay.
Topics: Bone Marrow; Cell Aggregation; Cell Division; Daunorubicin; Humans; Leukemia, Myeloid | 1982 |
Combination chemotherapy for terminal-phase chronic granulocytic leukemia: cancer and leukemia group B studies.
Topics: Daunorubicin; Dexamethasone; Drug Therapy, Combination; Gastrointestinal Diseases; Hemorrhage; Humans; Hydroxyurea; Infections; Leukemia, Myeloid; Mercaptopurine; Prednisone; Remission, Spontaneous; Terminal Care | 1980 |
Restoration of nonclonal hematopoiesis in chronic myelogenous leukemia (CML) following a chemotherapy-induced loss of the Ph1 chromosome.
Topics: Adult; Chromosome Aberrations; Chromosomes, Human, 21-22 and Y; Clone Cells; Cytarabine; Daunorubicin; Female; Glucosephosphate Dehydrogenase; Heterozygote; Humans; Karyotyping; Leukemia, Myeloid; Thioguanine | 1980 |
Re-induction of complete remissions in adults with acute non-lymphocytic leukemia.
Topics: Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Thioguanine | 1981 |
Individual nuclear uptake patterns for adriamycin and daunomycin in human leukemia and lymphoma cells.
Topics: Cell Nucleus; Daunorubicin; Doxorubicin; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma | 1981 |
Daunorubicin-prednisone in the treatment of acute nonlymphocytic leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Daunorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Male; Middle Aged; Prednisone; Time Factors | 1981 |
[Carminomycin in the therapy of leukemias].
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Carubicin; Daunorubicin; Drug Evaluation; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Middle Aged; Time Factors | 1982 |
Discordant P-glycoprotein antigen expression and transport function in acute myeloid leukemia.
Topics: Acute Disease; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Daunorubicin; Humans; Immunoassay; Leukemia, Myeloid; Tumor Cells, Cultured | 1995 |
Effect of Calphostin C (PKC inhibitor) on daunorubicin resistance in P388/ADR and HL60/AR cells: reversal of drug resistance possibly via P-glycoprotein.
Topics: Animals; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Coloring Agents; Daunorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Leukemia P388; Leukemia, Experimental; Leukemia, Myeloid; Membrane Glycoproteins; Mice; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Rhodamine 123; Rhodamines; Tumor Cells, Cultured | 1994 |
Sensitivities of AML blast stem cells to idarubicin and daunorubicin: a comparison with normal hematopoietic progenitors.
Topics: Aged; Aged, 80 and over; Blood Cells; Bone Marrow Cells; Cells, Cultured; Culture Techniques; Daunorubicin; Dose-Response Relationship, Drug; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Neoplastic Stem Cells; Recombinant Proteins; Tumor Cells, Cultured | 1995 |
Predictive value for treatment outcome in acute myeloid leukemia of cellular daunorubicin accumulation and P-glycoprotein expression simultaneously determined by flow cytometry.
Topics: Acute Disease; Adolescent; Adult; Aged; Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blast Crisis; Blood Cell Count; Bone Marrow; Chromosome Deletion; Chromosomes, Human, Pair 7; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Female; Flow Cytometry; Gene Expression; Humans; Idarubicin; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Monosomy; Myelodysplastic Syndromes; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Prognosis; Prospective Studies; Quinine; Remission Induction; Risk; Salvage Therapy; Treatment Outcome | 1995 |
CD7 expression does not predict for poor outcome in acute myeloblastic leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antigens, CD; Antigens, CD7; Antigens, Differentiation, T-Lymphocyte; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Neoplastic Stem Cells; Prognosis; Retrospective Studies; Survival Analysis; T-Lymphocyte Subsets | 1995 |
Multidrug resistant cells with high proliferative capacity determine response to therapy in acute myeloid leukemia.
Topics: Acute Disease; Age Factors; Analysis of Variance; Antigens, CD; Antigens, CD34; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biomarkers, Tumor; Bone Marrow; Cell Division; Cells, Cultured; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Monocytes; Predictive Value of Tests; Remission Induction; Survival Rate | 1995 |
Expression of apoptosis-related oncoproteins and modulation of apoptosis by caffeine in human leukemic cells.
Topics: Apoptosis; Caffeine; Carboplatin; Cluster Analysis; Coloring Agents; Daunorubicin; Drug Resistance, Neoplasm; Flow Cytometry; G2 Phase; Gamma Rays; Gene Expression Regulation, Leukemic; Glutathione; GTP-Binding Proteins; HL-60 Cells; Humans; Immunohistochemistry; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Lymphoma, Non-Hodgkin; Multivariate Analysis; Oncogene Proteins v-fos; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Radiation Tolerance; ras Proteins; S Phase; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1995 |
Group sequential methods for comparison of cure rates in clinical trials.
Topics: Acute Disease; Bone Marrow Transplantation; Child; Controlled Clinical Trials as Topic; Daunorubicin; Disease-Free Survival; Doxorubicin; Humans; Leukemia, Myeloid; Models, Statistical; Multicenter Studies as Topic; Nuclear Family; Survival Analysis; Tissue Donors | 1995 |
Synergistic and antagonistic effects of myeloid growth factors on in vitro cellular killing by cytotoxic drugs.
Topics: Aclarubicin; Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Death; Cell Survival; Coloring Agents; Cytarabine; Daunorubicin; Drug Antagonism; Drug Screening Assays, Antitumor; Drug Synergism; Female; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Leukemia, Myeloid; Male; Middle Aged; Prospective Studies; Remission Induction | 1993 |
[Results of induction therapy in newly diagnosed acute myeloid leukemias in study 911 at the Institute of Hematology and Blood Transfusion].
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Remission Induction | 1995 |
Transverse nail ridgings (Beau's lines) induced by chemotherapy--a dose-dependent phenomenon.
Topics: Acute Disease; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid; Nail Diseases; Nails | 1994 |
Lack of correlation between expression and function of P-glycoprotein in acute myeloid leukemia cell lines.
Topics: Acute Disease; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Differentiation; Coloring Agents; Daunorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Flow Cytometry; Gene Expression; Humans; Immunohistochemistry; Leukemia, Myeloid; Phenotype; Polymerase Chain Reaction; Rhodamine 123; Rhodamines; Transcription, Genetic; Tumor Cells, Cultured; Vincristine | 1995 |
Benefit of high-dose cytarabine-based consolidation chemotherapy for adults with acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; California; Cytarabine; Daunorubicin; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Mitoxantrone; Preleukemia; Remission Induction; Survival Analysis; Thioguanine; Treatment Outcome | 1994 |
Low frequency of activity of P-glycoprotein (P-170) in acute lymphoblastic leukemia compared to acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow; Bone Marrow Transplantation; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Resistance, Multiple; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplasm Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Prognosis; Remission Induction; Rhodamine 123; Rhodamines; Survival Analysis | 1995 |
Characterization of a human myeloid leukemia cell line highly resistant to taxol.
Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Cell Division; Cyclosporine; Daunorubicin; DNA, Neoplasm; Drug Resistance; Humans; Leukemia, Myeloid; Membrane Glycoproteins; Microtubules; Paclitaxel; Tumor Cells, Cultured; Verapamil | 1994 |
Circumvention of daunorubicin resistance by a new tamoxifen derivative, toremifene, in multidrug-resistant cell line.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Chemical Phenomena; Chemistry, Physical; Daunorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Leukemia, Myeloid; Membrane Glycoproteins; Phenotype; Solubility; Toremifene; Tumor Cells, Cultured; Verapamil | 1994 |
Flow cytometric monitoring of anthracycline accumulation after anti-neoplastic ether phospholipid treatment.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Daunorubicin; Drug Interactions; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Leukemia, Myeloid; Leukemia, T-Cell; Phospholipid Ethers; Tumor Cells, Cultured; Verapamil | 1994 |
In vitro drug resistance in acute myeloid and chronic B-lymphocytic leukaemic blasts and in normal blood and marrow populations.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blast Crisis; Bone Marrow; Bone Marrow Cells; Cell Survival; Cells, Cultured; Cyclosporine; Daunorubicin; Drug Resistance; Drug Resistance, Multiple; Female; Fluorescent Antibody Technique; Humans; Idarubicin; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Male; Middle Aged; Monocytes; Reference Values | 1994 |
Influence of idarubicinol on the antileukemic effect of idarubicin.
Topics: Daunorubicin; DNA; DNA Damage; Humans; Idarubicin; In Vitro Techniques; Leukemia, Myeloid; Nucleic Acid Synthesis Inhibitors; Tumor Cells, Cultured | 1994 |
Flow cytometric determination of the multidrug-resistant phenotype in acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blast Crisis; Child; Child, Preschool; Daunorubicin; Drug Resistance, Multiple; Female; Flow Cytometry; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Male; Middle Aged; Neoplasm Proteins; Phenotype; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Remission Induction; Salvage Therapy; Treatment Failure; Tumor Cells, Cultured; Verapamil; Vinblastine; Vincristine | 1994 |
Successful pregnancies in women following single autotransplant for acute myeloid leukemia with a chemotherapy ablation protocol.
Topics: Abortion, Induced; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Carmustine; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Infertility, Female; Leukemia, Myeloid; Menstruation; Middle Aged; Pregnancy; Pregnancy Outcome; Primary Ovarian Insufficiency; Remission Induction; Reoperation; Survivors; Thioguanine; Transplantation, Autologous | 1994 |
Comparative activity of tamoxifen and N-desmethyltamoxifen in human multidrug resistant leukemia cell lines.
Topics: Daunorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Humans; Leukemia, Myeloid; Phenotype; Tamoxifen; Tumor Cells, Cultured | 1994 |
Daunorubicin (DNR) accumulation in fresh leukemic cells: correlation with clinical and biological features.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Biological Transport; Bone Marrow; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Female; Flow Cytometry; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Neoplastic Stem Cells; Stimulation, Chemical; Treatment Failure; Verapamil | 1994 |
Daunorubicin uptake by leukemic cells: correlations with treatment outcome and mdr1 expression.
Topics: Acute Disease; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carrier Proteins; Cyclosporine; Daunorubicin; Drug Resistance; Gene Expression; Humans; In Vitro Techniques; Leukemia, Myeloid; Membrane Glycoproteins; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured | 1993 |
Toxicity of idarubicin and doxorubicin towards normal and leukemic human bone marrow progenitors in relation to their proliferative state.
Topics: Acute Disease; Antineoplastic Agents; Cell Division; Daunorubicin; Doxorubicin; Granulocytes; Hematopoietic Stem Cells; Humans; Idarubicin; Leukemia, Myeloid; Macrophages; Tumor Stem Cell Assay | 1994 |
Post-remission cytopenias following intense induction chemotherapy for acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Anemia; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Neutropenia; Recurrence; Remission Induction; Thrombocytopenia; Time Factors; Treatment Outcome | 1994 |
Effects of macrophage colony-stimulating factor (M-CSF) on the mobilization of peripheral blood stem cells.
Topics: Acute Disease; Adolescent; Adult; Blood Cells; Cell Movement; Cells, Cultured; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Female; Hematopoietic Stem Cells; Humans; Leukapheresis; Leukemia, Myeloid; Macrophage Colony-Stimulating Factor; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1994 |
[The current chemotherapy of acute myeloid leukemias in adults].
Topics: Aclarubicin; Acute Disease; Adult; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Humans; Idarubicin; Leukemia, Myeloid; Mitoxantrone; Prognosis; Remission Induction; Time Factors | 1993 |
Acute myeloid leukemia presenting as granulocytic sarcoma of the lung.
Topics: Acute Disease; Adult; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Diagnosis, Differential; Etoposide; Humans; Leukemia, Myeloid; Lung Neoplasms; Male | 1993 |
Enhancement of tumouricidal activity of daunomycin by receptor-mediated delivery. In vivo studies.
Topics: Animals; Cell Line, Transformed; Daunorubicin; Female; Iodine Radioisotopes; Leukemia, Myeloid; Mice; Mice, Inbred BALB C; Serum Albumin, Bovine | 1993 |
Treatment of childhood acute myeloid leukaemia using the BFM-83 protocol.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Combined Modality Therapy; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid; Life Tables; Male; Survival Analysis; Treatment Outcome | 1993 |
Clinical and prognostic significance of in vivo differentiation in acute myeloid leukemia.
Topics: Acute Disease; Antibodies, Monoclonal; Biopsy, Needle; Bone Marrow; Bromodeoxyuridine; Cell Cycle; Cell Differentiation; Cell Division; Cytarabine; Daunorubicin; Drug Therapy, Combination; Granulocytes; Humans; Leukemia, Myeloid; Prognosis; Remission Induction; Risk Factors | 1993 |
Neutrophilic eccrine hidradenitis.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Facial Dermatoses; Female; Hidradenitis; Humans; Leukemia, Myeloid; Precursor Cell Lymphoblastic Leukemia-Lymphoma | 1993 |
Incidence of chromosome abnormalities and clinical significance of karyotype in de novo acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Female; Humans; Incidence; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Translocation, Genetic | 1993 |
Selective discharge of patients with acute myeloid leukemia during chemotherapy-induced neutropenia.
Topics: Acute Disease; Adult; Ambulatory Care; Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Catheterization, Central Venous; Cross Infection; Cytarabine; Daunorubicin; Disease Susceptibility; Etoposide; Female; Fever; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neutropenia; Patient Discharge; Safety; Treatment Outcome | 1996 |
Central nervous system granulocytic sarcoma in a patient with essential thrombocythemia.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blast Crisis; Bone Marrow; Busulfan; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease Progression; Epidural Space; Fatal Outcome; Frontal Bone; Humans; Leukemia, Myeloid; Leukemic Infiltration; Male; Methylprednisolone; Spinal Canal; Thrombocythemia, Essential | 1996 |
Interpreting data in AML.
Topics: Acute Disease; Antineoplastic Agents; Bone Marrow Transplantation; Clinical Trials as Topic; Daunorubicin; Disease-Free Survival; Humans; Leukemia, Myeloid; Multicenter Studies as Topic; Prognosis; Research Design | 1996 |
Quality control of multidrug resistance assays in adult acute leukemia: correlation between assays for P-glycoprotein expression and activity.
Topics: Acute Disease; Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cryopreservation; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Feasibility Studies; Fluorescent Dyes; Humans; Leukemia; Leukemia, Myeloid; Neoplasm Proteins; Neoplastic Stem Cells; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Reproducibility of Results; Rhodamine 123; Rhodamines; Sensitivity and Specificity; Verapamil; Vincristine | 1996 |
Renal venous thrombosis complicating acute myeloid leukemia with hyperleukocytosis.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Atrophy; Cytarabine; Daunorubicin; Humans; Infant; Kidney; Leukapheresis; Leukemia, Myeloid; Leukocyte Count; Leukocytosis; Male; Renal Veins; Thioguanine; Thrombosis; Tomography, X-Ray Computed; Ultrasonography, Doppler | 1996 |
High-dose cytarabine induction for acute myeloid leukemia.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid; Randomized Controlled Trials as Topic; Remission Induction; Treatment Outcome | 1996 |
Relation of blast cell survival and proliferation to chemotherapy resistance in AML.
Topics: Aclarubicin; Adolescent; Adult; Aged; Antineoplastic Agents; Cell Differentiation; Cell Survival; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Female; Humans; Infant; Infant, Newborn; Leukemia, Myeloid; Leukocyte Count; Male; Middle Aged; Mitoxantrone; Treatment Outcome; Tumor Cells, Cultured | 1996 |
In vitro resistance to cytosine arabinoside, not to daunorubicin, is associated with the risk of relapse in de novo acute myeloid leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Amsacrine; Antigens, CD34; Antineoplastic Agents; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Recurrence; Risk Factors; Treatment Outcome | 1996 |
Expression of Fas antigen in acute myeloid leukaemia is associated with therapeutic response to chemotherapy.
Topics: Acute Disease; Adult; Antineoplastic Agents; Bone Marrow; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; fas Receptor; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Thioguanine; Treatment Outcome | 1996 |
[Predictive value of intracellular accumulation of daunorubicin and P-glycoprotein expression simultaneously determined by flow cytometry in adult acute myeloid leukemias].
Topics: Acute Disease; Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow; Daunorubicin; Drug Resistance, Multiple; Flow Cytometry; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid; Multivariate Analysis; Phenotype; Prospective Studies | 1996 |
Autologous transplantation with peripheral blood stem cells collected after granulocyte colony-stimulating factor in patients with acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Blood Cell Count; Blood Cells; Bone Marrow; Bone Marrow Transplantation; Busulfan; Child; Child, Preschool; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Disease-Free Survival; Etoposide; Graft Survival; Granulocyte Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Life Tables; Middle Aged; Mitoxantrone; Recombinant Proteins; Remission Induction; Retrospective Studies; Salvage Therapy; Survival Analysis; Thioguanine; Transplantation Conditioning; Transplantation, Autologous; Treatment Outcome; Whole-Body Irradiation | 1996 |
Cerebellar toxicity with medium-dose cytarabine in a young patient with renal insufficiency.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Diseases; Cytarabine; Daunorubicin; Female; Humans; Kidney; Kidney Failure, Chronic; Leukemia, Myeloid; Lupus Nephritis; Mitoxantrone | 1996 |
Measurement of spontaneous and therapeutic agent-induced apoptosis with BCL-2 protein expression in acute myeloid leukemia.
Topics: Acute Disease; Antineoplastic Agents; Apoptosis; Bone Marrow; Cell Separation; Cytarabine; Daunorubicin; Disease Progression; Flow Cytometry; Gene Expression Regulation, Leukemic; Genes, p53; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid; Neoplasm Proteins; Neoplastic Stem Cells; Proto-Oncogene Proteins c-bcl-2; Reproducibility of Results; Sensitivity and Specificity; Tumor Cells, Cultured | 1997 |
Protective effects of cardioxane against anthracycline-induced cardiotoxicity in relapsed acute myeloid leukemias.
Topics: Acute Disease; Antibiotics, Antineoplastic; Antineoplastic Agents; Cardiovascular Agents; Cytarabine; Daunorubicin; Female; Heart; Humans; Leukemia, Myeloid; Male; Middle Aged; Razoxane; Recurrence | 1996 |
A novel energy dependent mechanism reducing daunorubicin accumulation in acute myeloid leukemia.
Topics: Acute Disease; Adenosine Triphosphate; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blast Crisis; Cyclosporine; Daunorubicin; Flow Cytometry; Humans; Leukemia, Myeloid; Potassium Cyanide; RNA, Messenger; Tumor Cells, Cultured | 1997 |
An anti-cancer derivative of butyric acid (pivalyloxmethyl buterate) and daunorubicin cooperatively prolong survival of mice inoculated with monocytic leukaemia cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Butyrates; Cell Differentiation; Cell Division; Daunorubicin; Drug Screening Assays, Antitumor; Female; Humans; Leukemia, Myeloid; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Survival Analysis; Tumor Cells, Cultured | 1997 |
Vesicular anthracycline accumulation in doxorubicin-selected U-937 cells: participation of lysosomes.
Topics: Antibiotics, Antineoplastic; Antigens, CD; Antigens, Neoplasm; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Biomarkers; Chloroquine; Cytoplasm; Daunorubicin; Doxorubicin; Drug Resistance, Neoplasm; Humans; Hydrogen-Ion Concentration; Leukemia, Myeloid; Lymphoma, Large B-Cell, Diffuse; Lysosomal Membrane Proteins; Lysosomes; Membrane Glycoproteins; Microscopy, Fluorescence; Neoplasm Proteins; Selection, Genetic; Tumor Cells, Cultured | 1997 |
Activity of thymidine kinase and of polymerase alpha as well as activity and gene expression of deoxycytidine deaminase in leukemic blasts are correlated with clinical response in the setting of granulocyte-macrophage colony-stimulating factor-based primi
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Cytidine Deaminase; Daunorubicin; DNA Polymerase II; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Lymphocytes; Male; Middle Aged; Nucleoside Deaminases; Thioguanine; Thymidine Kinase | 1997 |
Myeloblasts from Down syndrome children with acute myeloid leukemia have increased in vitro sensitivity to cytosine arabinoside and daunorubicin.
Topics: Acute Disease; Bone Marrow; Cell Survival; Child; Cytarabine; Daunorubicin; Down Syndrome; Humans; Leukemia, Myeloid; Tumor Cells, Cultured | 1997 |
Expression of c-Kit and functional drug efflux are correlated in de novo acute myeloid leukaemia.
Topics: Acute Disease; Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Fluorescent Antibody Technique, Indirect; Humans; Immunosuppressive Agents; Leukemia, Myeloid; Phenotype; Proto-Oncogene Proteins c-kit; Rhodamine 123; Rhodamines; Tumor Cells, Cultured | 1997 |
Non-transferrin-bound iron induced by myeloablative chemotherapy.
Topics: Adolescent; Adult; Blood Transfusion; Daunorubicin; Female; Hematopoiesis; Hodgkin Disease; Humans; Iron; Leukemia, Myeloid; Lymphoma, Non-Hodgkin; Male; Middle Aged; Myeloablative Agonists; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Receptors, Transferrin; Transferrin; Transplantation Conditioning | 1997 |
Effect on cell kill of addition of multidrug resistance modifiers cyclosporin A and PSC 833 to cytotoxic agents in acute myeloid leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Survival; Coloring Agents; Cyclosporine; Cyclosporins; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Drug Synergism; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 1997 |
The prognostic significance of chromosomal analysis and immunophenotyping in 117 patients with de novo acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Antibiotics, Antineoplastic; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Immunophenotyping; Karyotyping; Leukemia, Myeloid; Male; Middle Aged; Multivariate Analysis; Prognosis; Remission Induction; Retrospective Studies; Sialic Acid Binding Ig-like Lectin 3 | 1997 |
Differential expression and activity of P-glycoprotein and multidrug resistance-associated protein in CD34-positive KG1a leukemic cells.
Topics: Activated-Leukocyte Cell Adhesion Molecule; Antigens, CD34; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cell Division; Daunorubicin; Drug Resistance; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; K562 Cells; Leukemia, Myeloid; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Vincristine | 1998 |
MDR1 gene expression and drug resistance of AML cells.
Topics: Aclarubicin; Acute Disease; Antineoplastic Agents; Cytarabine; Daunorubicin; Doxorubicin; Drug Resistance, Neoplasm; Etoposide; Gene Expression; Genes, MDR; Humans; Lethal Dose 50; Leukemia, Myeloid; Mitoxantrone; Tumor Cells, Cultured | 1998 |
Cell cycle perturbations in acute myeloid leukemia samples following in vitro exposures to therapeutic agents.
Topics: Acute Disease; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Cell Cycle; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Flow Cytometry; Genes, p53; Humans; Immunophenotyping; Karyotyping; Leukemia, Myeloid; Mutation; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2; Reproducibility of Results; Sensitivity and Specificity | 1998 |
Evidence for a critical role of DNA topoisomerase IIalpha in drug sensitivity revealed by inducible antisense RNA in a human leukaemia cell line.
Topics: Antibiotics, Antineoplastic; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Blotting, Southern; Cell Survival; Cyclophosphamide; Daunorubicin; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Etoposide; Gene Expression; Humans; Isoenzymes; Leukemia, Myeloid; RNA, Antisense; RNA, Messenger; Tumor Cells, Cultured | 1998 |
Cellular immune responses in acute leukaemia patients with severe chemotherapy-induced leucopenia; characterization of the cytokine repertoire of clonogenic T cells.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Clone Cells; Cytarabine; Cytokines; Daunorubicin; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-10; Interleukin-2; Leukemia, Myeloid; Leukopenia; Lymphopenia; Male; Middle Aged; Phytohemagglutinins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Stimulation, Chemical | 1998 |
Impact of exogenous growth factors on proliferation and chemosensitivity of minimal residual acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Ki-67 Antigen; Leukemia, Myeloid; Middle Aged; Neoplasm, Residual; Remission Induction; Tumor Stem Cell Assay | 1998 |
A rare atypical myeloproliferative-disorder-like hemopathy with marked dysplasia, peripheral dominant myeloblast proliferation and extramedullary hematopoiesis was converted into typical acute myeloid leukemia with an interval of complete hematological re
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Disease Progression; Hematopoiesis, Extramedullary; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Myelodysplastic Syndromes; Myeloproliferative Disorders; Prednisolone; Preleukemia; Remission Induction | 1998 |
Proportion of blasts with a clear halo around nucleoli at the end of induction therapy of acute myeloid leukemia correlates with achievement of complete remission, remission duration and relapse.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Cells; Cell Nucleolus; Child; Child, Preschool; Cytarabine; Daunorubicin; Disease-Free Survival; Humans; Immunoenzyme Techniques; Ki-67 Antigen; Leukemia, Myeloid; Mercaptopurine; Middle Aged; Neoplasm Recurrence, Local; Prednisolone; Remission Induction; Retrospective Studies; Vincristine | 1998 |
Intensifying induction therapy in acute myeloid leukemia by an infusional chemotherapy schedule.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Humans; Leukemia, Myeloid; Middle Aged; Remission Induction | 1998 |
Functional multidrug resistance phenotype associated with combined overexpression of Pgp/MDR1 and MRP together with 1-beta-D-arabinofuranosylcytosine sensitivity may predict clinical response in acute myeloid leukemia.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Cytarabine; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Etoposide; Humans; KB Cells; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Multidrug Resistance-Associated Proteins; Phenotype; Prognosis; Treatment Outcome; Tumor Cells, Cultured | 1995 |
P-glycoprotein expression and prognostic value in acute myeloid leukemia.
Topics: Actuarial Analysis; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Child; Cohort Studies; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Female; Genes, MDR; Humans; Leukemia, Myeloid; Leukocyte Count; Male; Middle Aged; Mitoxantrone; Neoplasm Proteins; Neoplastic Stem Cells; Prognosis; Remission Induction | 1998 |
Influence of SDZ-PSC833 on daunorubicin intracellular accumulation in bone marrow specimens from patients with acute myeloid leukaemia.
Topics: Acute Disease; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow; Cyclosporine; Cyclosporins; Daunorubicin; Drug Interactions; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Immunosuppressive Agents; Leukemia, Myeloid; Tumor Cells, Cultured | 1998 |
Prophylactic platelet transfusion threshold during therapy for adult acute myeloid leukemia: 10,000/microL versus 20,000/microL.
Topics: Acute Disease; Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Hemorrhage; Humans; Idarubicin; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Pancytopenia; Platelet Count; Platelet Transfusion; Retrospective Studies; Spain; Thrombocytopenia | 1998 |
Do P-glycoprotein and major vault protein (MVP/LRP) expression correlate with in vitro daunorubicin resistance in acute myeloid leukemia?
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Daunorubicin; Drug Resistance, Neoplasm; Humans; Immunohistochemistry; Lethal Dose 50; Leukemia, Myeloid; Middle Aged; Vault Ribonucleoprotein Particles | 1999 |
Intraclonal heterogeneity in the in vitro daunorubicin-induced apoptosis in acute myeloid leukemia.
Topics: Acute Disease; Apoptosis; Cell Separation; Clone Cells; Daunorubicin; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1999 |
Sodium salicylate activates caspases and induces apoptosis of myeloid leukemia cell lines.
Topics: Amino Acid Chloromethyl Ketones; Annexin A5; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Apoptosis; Caspase 3; Caspases; Cysteine Proteinase Inhibitors; Daunorubicin; Drug Synergism; Enzyme Activation; Gelsolin; Gene Expression Regulation, Leukemic; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; K562 Cells; Leukemia, Myeloid; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-bcl-2; Sodium Salicylate; Tumor Cells, Cultured | 1999 |
Idarubicin more cost-effective than daunorubicin?
Topics: Cost-Benefit Analysis; Daunorubicin; Hospital Charges; Hospital Costs; Humans; Leukemia, Myeloid; Randomized Controlled Trials as Topic; Treatment Outcome | 1992 |
The phosphoinositide 3-kinase/Akt pathway is activated by daunorubicin in human acute myeloid leukemia cell lines.
Topics: Acute Disease; Androstadienes; Apoptosis; Ceramides; Chromones; Daunorubicin; Enzyme Activation; Enzyme Inhibitors; Humans; Kinetics; Leukemia, Myeloid; Morpholines; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; U937 Cells; Wortmannin | 1999 |
A new PCR MIMIC strategy to quantify low mdr1 mRNA levels in drug resistant cell lines and AML blast samples.
Topics: Acute Disease; Adolescent; Adult; Aged; Antigens, CD34; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Chromosome Banding; Cytarabine; Daunorubicin; DNA, Complementary; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Leukemic; Genes, MDR; Humans; K562 Cells; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Neoplasm Proteins; Neoplastic Stem Cells; Oligonucleotide Probes; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Neoplasm; Sensitivity and Specificity; Tumor Cells, Cultured | 1999 |
Anti-psychotic drugs reverse multidrug resistance of tumor cell lines and human AML cells ex-vivo.
Topics: Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Daunorubicin; Drug Interactions; Drug Resistance, Multiple; Enzyme Inhibitors; Humans; Leukemia, Myeloid; Rhodamine 123; Tumor Cells, Cultured | 1999 |
Simultaneous activity of MRP1 and Pgp is correlated with in vitro resistance to daunorubicin and with in vivo resistance in adult acute myeloid leukemia.
Topics: Acute Disease; Adult; Aged; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Daunorubicin; DNA-Binding Proteins; Drug Resistance, Microbial; Humans; Leukemia, Myeloid; Middle Aged; Multidrug Resistance-Associated Proteins; MutS Homolog 3 Protein | 1999 |
Expression of chromosome 21-localized genes in acute myeloid leukemia: differences between Down syndrome and non-Down syndrome blast cells and relationship to in vitro sensitivity to cytosine arabinoside and daunorubicin.
Topics: Adolescent; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Child; Child, Preschool; Chromosomes, Human, Pair 21; Cytarabine; Daunorubicin; Down Syndrome; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Infant; Infant, Newborn; Leukemia, Myeloid; Leukocytes; Tumor Cells, Cultured | 1999 |
Leukaemia cell drug resistance and prognostic factors in AML.
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Blast Crisis; Child; Child, Preschool; Cytarabine; Cytogenetic Analysis; Daunorubicin; Drug Resistance, Neoplasm; Female; Humans; Infant; Leukemia, Myeloid; Male; Middle Aged; Multivariate Analysis; Prognosis; Tetrazolium Salts | 1999 |
Molecular effects of topoisomerase II inhibitors in AML cell lines: correlation of apoptosis with topoisomerase II activity but not with DNA damage.
Topics: Aclarubicin; Acute Disease; Antineoplastic Agents; Apoptosis; Cell Nucleus; Comet Assay; Daunorubicin; DNA; DNA Damage; DNA Topoisomerases, Type II; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Etoposide; fas Receptor; Genes, p53; Humans; Intercalating Agents; Leukemia, Myeloid; Mitochondria; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 1999 |
Acute minimally differentiated myeloid leukemia (M0) with inv(3)(q21q26).
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation; Chromosome Inversion; Chromosomes, Human, Pair 3; Cytarabine; Daunorubicin; Fatal Outcome; Humans; Leukemia, Myeloid; Male; Middle Aged; Prednisolone | 1999 |
In vitro cellular accumulation and cytotoxicity of liposomal and conventional formulations of daunorubicin and doxorubicin in resistant K562 cells.
Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Chromatography, High Pressure Liquid; Daunorubicin; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Doxorubicin; Drug Carriers; Drug Compounding; Drug Resistance, Neoplasm; Fluorometry; Humans; K562 Cells; Leukemia, Myeloid; Liposomes | 1999 |
Effects of retinoids on cell toxicity and apoptosis in leukemic blast cells from patients with non-M3 AML.
Topics: Acute Disease; Adenosine Triphosphate; Adult; Aged; Aged, 80 and over; Alitretinoin; Antibiotics, Antineoplastic; Antigens, CD34; Antineoplastic Agents; Apoptosis; Daunorubicin; Drug Synergism; Female; Hematopoietic Stem Cells; Humans; Leukemia, Myeloid; Male; Middle Aged; Neoplastic Stem Cells; Tretinoin; Tumor Cells, Cultured | 2000 |
P-glycoprotein and multidrug resistance-associated protein, but not lung resistance protein, lower the intracellular daunorubicin accumulation in acute myeloid leukaemic cells.
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Flow Cytometry; Humans; Immunohistochemistry; Leukemia, Myeloid; Male; Middle Aged; Neoplasm Proteins; Survival Analysis; Treatment Outcome; Vault Ribonucleoprotein Particles | 2000 |
Mild pre-transplant cardiomyopathy may not impair long-term quality of life after bone marrow transplantation.
Topics: Acute Disease; Anthracyclines; Bone Marrow Transplantation; Cardiomyopathies; Child; Cytarabine; Daunorubicin; Electroencephalography; Graft vs Host Disease; Humans; Immunosuppressive Agents; Karnofsky Performance Status; Leukemia, Myeloid; Male; Quality of Life; Transplantation, Homologous | 2000 |
Heterogeneity of isolated mononuclear cells from patients with acute myeloid leukemia affects cellular accumulation and efflux of daunorubicin.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Cell Differentiation; Daunorubicin; Female; Humans; Leukemia, Myeloid; Leukocytes, Mononuclear; Male; Middle Aged | 2000 |
Diverse effects of P-glycoprotein inhibitory agents on human leukemia cells expressing the multidrug resistance protein (MRP).
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Cyclosporins; Daunorubicin; Dibenzocycloheptenes; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluorescence; Humans; Leukemia, Myeloid; Peptides, Cyclic; Quinolines; Tumor Cells, Cultured | 2000 |
In vitro chemosensitivity testing in acute non lymphocytic leukemia using the bioluminescence ATP assay.
Topics: Acute Disease; Adenosine Triphosphate; Antibiotics, Antineoplastic; Biological Assay; Cell Survival; Daunorubicin; Drug Resistance, Microbial; Drug Resistance, Neoplasm; Humans; Leukemia, Myeloid; Luminescent Measurements; Sensitivity and Specificity; Tumor Cells, Cultured | 2000 |
Granulocyte macrophage--colony stimulating factor (GM-CSF) as adjunct in induction therapy of acute myeloid leukemia.
Topics: Acute Disease; Adjuvants, Immunologic; Adolescent; Adult; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Fever; Follow-Up Studies; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Male; Middle Aged; Neoplasm Recurrence, Local; Neutropenia; Remission Induction | 1999 |
Primary granulocytic sarcoma of the ovary.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Ovarian Neoplasms; Remission Induction | 2000 |
High-dose cytosine arabinoside and daunorubicin induction therapy for adult patients with de novo non M3 acute myelogenous leukemia: impact of cytogenetics on achieving a complete remission.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cerebellar Diseases; Chromosome Aberrations; Chromosome Deletion; Chromosome Inversion; Chromosomes, Human; Chromosomes, Human, Pair 7; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Logistic Models; Male; Middle Aged; Prognosis; Remission Induction; Retrospective Studies; Sepsis; Translocation, Genetic; Treatment Outcome | 2000 |
Study of apoptosis-related responses of leukemic blast cells to in vitro anthracycline treatment.
Topics: Acute Disease; Adolescent; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Marrow; Caspase 3; Caspases; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Activation; fas Receptor; Female; Flow Cytometry; Gene Expression Regulation, Leukemic; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Neoplasm Proteins; Neoplastic Stem Cells; Peptide Hydrolases; Prognosis; Remission Induction; Signal Transduction; Survival Analysis; Treatment Outcome | 2000 |
Human acute myeloid leukemia CD34+/CD38- progenitor cells have decreased sensitivity to chemotherapy and Fas-induced apoptosis, reduced immunogenicity, and impaired dendritic cell transformation capacities.
Topics: Acute Disease; ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antibiotics, Antineoplastic; Antigens, CD; Antigens, CD34; Antigens, Differentiation; Apoptosis; B7-1 Antigen; B7-2 Antigen; CD58 Antigens; Cell Differentiation; Daunorubicin; Dendritic Cells; Drug Resistance, Neoplasm; Fas Ligand Protein; fas Receptor; Gene Expression; Hematopoietic Stem Cells; HLA-DR Antigens; Humans; Leukemia, Myeloid; Major Histocompatibility Complex; Membrane Glycoproteins; NAD+ Nucleosidase; Neoplastic Stem Cells; RNA, Messenger | 2000 |
Bullous acral erythema and concomitant pigmentation on the face and occluded skin.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Cytarabine; Daunorubicin; Drug Eruptions; Erythema; Female; Hand Dermatoses; Humans; Hyperpigmentation; Leukemia, Myeloid; Skin Diseases, Vesiculobullous | 2000 |
[Poor response in patients with de novo acute myeloid leukemia and erythroblastic or megakaryocytic dysplasia to treatment with standard doses of cytosine arabinoside and daunorubicin].
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Refractory, with Excess of Blasts; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cytarabine; Daunorubicin; Erythroblasts; Humans; Leukemia, Myeloid; Megakaryocytes; Middle Aged | 1999 |
Nucleus labeling or membrane labeling for studying the proliferation of drug treated cells?
Topics: Acute Disease; Antineoplastic Agents; Cell Cycle; Cell Division; Cell Membrane; Cell Membrane Permeability; Cell Nucleus; Cytarabine; Daunorubicin; DNA, Neoplasm; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluorescent Dyes; Humans; K562 Cells; Leukemia, Myeloid; Propidium | 2000 |
Allogeneic bone marrow transplantation improves the outcome of de novo AML with trilineage dysplasia (AML-TLD).
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Cell Lineage; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Female; Humans; Japan; Leukemia, Myeloid; Life Tables; Male; Middle Aged; Neoplastic Stem Cells; Remission Induction; Retrospective Studies; Survival Analysis; Transplantation Conditioning; Transplantation, Homologous; Treatment Outcome; Tretinoin | 2000 |
Corticosteroids and serious cytarabine-induced pulmonary edema.
Topics: Aged; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Cytarabine; Daunorubicin; Fatal Outcome; Female; Glucocorticoids; Humans; Leukemia, Myeloid; Methylprednisolone; Radiography; Respiratory Distress Syndrome | 2000 |
Blasts from elderly acute myeloid leukemia patients are characterized by low levels of culture- and drug-induced apoptosis.
Topics: Acute Disease; Adult; Aged; Aging; Antibiotics, Antineoplastic; Antigens, CD34; Antimetabolites, Antineoplastic; Apoptosis; Bone Marrow Cells; Cell Cycle; Cytarabine; Daunorubicin; G2 Phase; Humans; Leukemia, Myeloid; Middle Aged; Mitosis; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2; S Phase; Tumor Cells, Cultured | 2001 |
De novo acute myeloid leukemia in the elderly; a consistent fraction of long-term survivors by standard-dose chemotherapy.
Topics: Acute Disease; Aged; Aged, 80 and over; Aging; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Karyotyping; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Prognosis; Treatment Outcome; Tretinoin | 2001 |
Mutations in ras proto-oncogenes are associated with lower mdr1 gene expression in adult acute myeloid leukaemia.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP-Binding Cassette Transporters; Case-Control Studies; Cytarabine; Daunorubicin; Female; Gene Expression; Genes, MDR; Genes, ras; Humans; Leukemia, Myeloid; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Mutation; Prospective Studies; Protein Tyrosine Phosphatases; Receptor-Like Protein Tyrosine Phosphatases, Class 4; Receptors, Cell Surface; Reverse Transcriptase Polymerase Chain Reaction | 2001 |
Cyclosporin increases cellular idarubicin and idarubicinol concentrations in relapsed or refractory AML mainly due to reduced systemic clearance.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cyclosporine; Daunorubicin; Female; Humans; Idarubicin; Immunosuppressive Agents; Leukemia, Myeloid; Male; Middle Aged; Pilot Projects; Prospective Studies; Recurrence | 2001 |
Neutrophilic eccrine hidradenitis in two neutropaenic patients.
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Hidradenitis; Humans; Leukemia, Myeloid; Mitoxantrone | 2001 |
Intracellular P-gp contributes to functional drug efflux and resistance in acute myeloid leukaemia.
Topics: Acute Disease; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cell Death; Cell Survival; Cyclosporine; Daunorubicin; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Multiple; Flow Cytometry; HL-60 Cells; Humans; K562 Cells; Leukemia, Myeloid; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; RNA, Messenger; Vault Ribonucleoprotein Particles; Verapamil | 2001 |
Pretreatment leukaemia cell drug resistance is correlated to clinical outcome in acute myeloid leukaemia.
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Neoplastic Stem Cells; Prognosis; Remission Induction; Survival Analysis; Thioguanine; Treatment Outcome; Tumor Cells, Cultured | 2001 |
Patterns of failure with increasing intensification of induction chemotherapy for acute myeloid leukaemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Australia; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Administration Schedule; Etoposide; Humans; Incidence; Leukemia, Myeloid; Middle Aged; Proportional Hazards Models; Randomized Controlled Trials as Topic; Remission Induction; Risk Assessment; Survival Rate; Time Factors; Treatment Failure | 2001 |
A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Benzimidazoles; Cell Separation; Child; Child, Preschool; Daunorubicin; Drug Resistance; Female; Humans; Immunophenotyping; Infant; Leukemia, Myeloid; Leukocytes, Mononuclear; Male; Mice; Mice, Inbred NOD; Middle Aged; Mitoxantrone; Myelodysplastic Syndromes; Neoplasm Transplantation; Neoplasms, Second Primary; Stem Cell Transplantation; Stem Cells; Tumor Cells, Cultured | 2001 |
Remission induction therapy: the more intensive the better?
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Daunorubicin; Dose-Response Relationship, Drug; Humans; Leukemia, Myeloid; Middle Aged; Remission Induction; Thioguanine | 2001 |
Therapy-related CD7+ acute myeloid leukemia with trisomy 8 following acute monocytic leukemia.
Topics: Antigens, CD7; Biomarkers, Tumor; Chromosomes, Human, Pair 8; Cytarabine; Daunorubicin; Diagnosis, Differential; Female; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Mercaptopurine; Middle Aged; Neoplasms, Second Primary; Prednisolone; Trisomy | 2001 |
Breast cancer resistance protein expression and resistance to daunorubicin in blast cells from patients with acute myeloid leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Immunoenzyme Techniques; Leukemia, Myeloid; Middle Aged; Neoplasm Proteins; Tumor Cells, Cultured | 2001 |
PK11195, a peripheral benzodiazepine receptor ligand, chemosensitizes acute myeloid leukemia cells to relevant therapeutic agents by more than one mechanism.
Topics: Acute Disease; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Cytarabine; Daunorubicin; DNA, Neoplasm; Drug Resistance, Multiple; Flow Cytometry; Humans; Isoquinolines; Leukemia, Myeloid; Ligands; Receptors, GABA-A; Tumor Cells, Cultured | 2002 |
Evaluation of the clinical relevance of the expression and function of P-glycoprotein, multidrug resistance protein and lung resistance protein in patients with primary acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow Transplantation; Calcium Channel Blockers; Carbocyanines; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Fluoresceins; Fluorescent Dyes; Genistein; Humans; Idarubicin; Immunophenotyping; Leukemia, Myeloid; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Probenecid; Prognosis; Prospective Studies; Rhodamine 123; Survival Analysis; Tumor Cells, Cultured; Vault Ribonucleoprotein Particles; Verapamil | 2002 |
Hematopoietic cell transplantation beyond first remission.
Topics: Acute Disease; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Comorbidity; Cyclosporine; Cytarabine; Daunorubicin; Disease-Free Survival; Follow-Up Studies; Graft Survival; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Nuclear Family; Prospective Studies; Randomized Controlled Trials as Topic; Remission Induction; Salvage Therapy; Survival Rate; Tissue Donors; Transplantation, Homologous; Treatment Outcome; Vidarabine | 2002 |
Prognosis of elderly patients with acute myelogenous leukemia: analysis of 126 AML cases.
Topics: Acute Disease; Age Factors; Aged; Allopurinol; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cholinesterases; Cytarabine; Daunorubicin; Disease Progression; Female; Humans; Japan; Karyotyping; Leukemia, Myeloid; Life Tables; Male; Mercaptopurine; Middle Aged; Myelodysplastic Syndromes; Neoplasm Proteins; Prognosis; Remission Induction; Risk Factors; Survival Analysis; Survival Rate | 2002 |
FAB M4 and high CD14 surface expression is associated with high cellular resistance to Ara-C and daunorubicin: implications for clinical outcome in acute myeloid leukaemia.
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Amsacrine; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cohort Studies; Cytarabine; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Female; Humans; Idarubicin; Leukemia, Myeloid; Leukemia, Myelomonocytic, Acute; Lipopolysaccharide Receptors; Male; Middle Aged; Mitoxantrone; Multivariate Analysis; Neoplastic Stem Cells; Thioguanine; Treatment Outcome | 2001 |
Immunotherapy by non-myeloablative stem cell transplantation: study of the immune reconstitution. Arguments for distinct cell subsets in skin and blood.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Blood; Blood Cells; Carmustine; CD8-Positive T-Lymphocytes; Clone Cells; Cyclophosphamide; Cytarabine; Daunorubicin; Dexamethasone; Doxorubicin; Female; Graft Survival; Graft vs Host Reaction; Graft vs Leukemia Effect; Hematopoietic Stem Cell Transplantation; Humans; Immunophenotyping; Immunotherapy; Leukemia, Myeloid; Male; Middle Aged; Minisatellite Repeats; Multiple Myeloma; Prednisone; Receptors, Antigen, T-Cell, alpha-beta; Skin; T-Lymphocyte Subsets; Transplantation Conditioning; Transplantation, Homologous; Vincristine; Whole-Body Irradiation | 2000 |
Role for c-jun N-terminal kinase in treatment-refractory acute myeloid leukemia (AML): signaling to multidrug-efflux and hyperproliferation.
Topics: Acute Disease; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow Cells; Cell Division; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; HL-60 Cells; Humans; JNK Mitogen-Activated Protein Kinases; Leukemia, Myeloid; Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-jun; Signal Transduction | 2002 |
Homocamptothecin-daunorubicin association overcomes multidrug-resistance in breast cancer MCF7 cells.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Camptothecin; Carcinoma; Colonic Neoplasms; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Leukemia, Myeloid; Microbial Sensitivity Tests; Multidrug Resistance-Associated Proteins; Polymerase Chain Reaction; RNA, Neoplasm; Treatment Outcome; Tumor Cells, Cultured | 2002 |
The therapy of acute leukemia in the adult: a progress report.
Topics: Acute Disease; Adult; Antineoplastic Agents; Azacitidine; Blood Transfusion; Cytarabine; Daunorubicin; Dexamethasone; Etoposide; Granulocytes; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Patient Isolation; Platelet Transfusion; Pneumonia; Prednisone; Pyrimethamine; Remission, Spontaneous; Thioguanine; Vincristine; Zinostatin | 1976 |
A 13-years remission in chronic myelocytic leukemia after a single course of busulfan.
Topics: Adult; Busulfan; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Remission, Spontaneous; Time Factors | 1978 |
Timed sequential therapy of human leukemia based upon the response of leukemic cells to humoral growth factors.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cell Division; Child; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Growth Substances; Humans; Leukemia, Myeloid; Male; Middle Aged; Remission, Spontaneous; Thymidine | 1977 |
Multiple-drug chemotherapy for acute leukemia The TRAMPCOL regimen: results in 86 patients.
Topics: Adolescent; Asparaginase; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Methotrexate; Prednisolone; Remission, Spontaneous; Thioguanine; Vincristine | 1977 |
[Treatment of acute leukemia].
Topics: Acute Disease; Adolescent; Adult; Aging; Asparaginase; Child; Child, Preschool; Daunorubicin; Humans; Infant; Leukemia; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Remission, Spontaneous; Time Factors | 1977 |
Some new aspects of modern cancer chemotherapy.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Survival; Daunorubicin; Drug Therapy, Combination; Humans; Kinetics; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid; Methotrexate; Mitosis; Neoplasms; Neuraminidase; Prednisone; Vincristine | 1977 |
Normal and leukemic hemopoiesis compared.
Topics: Cell Survival; Colony-Forming Units Assay; Daunorubicin; Doxorubicin; Erythropoiesis; Granulocytes; Hematopoiesis; Humans; In Vitro Techniques; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Phytohemagglutinins | 1978 |
[Intensive treatment aiming at eradication of chronic myelogeneous leukemia (author's transl)].
Topics: Adolescent; Adult; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Prednisolone; Splenectomy | 1978 |
Comparative studies on phenol-soluble nonhistone chromatin proteins in normal and leukaemic human leukocytes.
Topics: Chromatin; Daunorubicin; Doxorubicin; Electrophoresis; Granulocytes; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukocytes; Lymphocytes; Neoplasm Proteins; Phenols; Solubility | 1979 |
Serial studies on in vitro colony formation in patients with acute leukemia in relation to the maintenance of remission.
Topics: Acute Disease; Adult; Child; Colony-Forming Units Assay; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Prednisolone; Remission, Spontaneous | 1978 |
[Complete clinical remission over 50 months of a patient with acute monocytic leukaemia (author's transl)].
Topics: Adult; Cytarabine; Daunorubicin; Drug Therapy, Combination; Gingival Hypertrophy; Humans; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Male; Remission, Spontaneous | 1979 |
[Program O9 OML 71 and splenectomy in the treatment of myelocytic leukemia].
Topics: Adult; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid; Middle Aged; Prednisolone; Splenectomy | 1979 |
[Splenectomy and polychemotherapy in chronic myelosis].
Topics: Busulfan; Cytarabine; Daunorubicin; Humans; Hydroxyurea; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Mitobronitol; Prognosis; Splenectomy; Vincristine | 1979 |
Sensitization of resistant myeloid leukemia clone cells by anti-cancer drugs to factor-stimulating differentiation.
Topics: Antineoplastic Agents; Ascitic Fluid; Cell Differentiation; Cell Line; Clone Cells; Colony-Stimulating Factors; Daunorubicin; Doxorubicin; Fluorouracil; In Vitro Techniques; Leukemia, Myeloid; Methotrexate; Mitomycins; Muramidase; Phagocytosis | 1979 |
[Monocytic leukemia. Analysis of clinical and hematological data in 21 patients (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Aged; Bone Marrow Examination; Chronic Disease; Cytarabine; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Female; Histocytochemistry; Humans; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Monocytes; Sternum; Vincristine | 1977 |
[A case of acute promyelocytic leukemia treated with quadruple combination therapy and bone marrow transfusion (author's transl)].
Topics: Adult; Bone Marrow Cells; Bone Marrow Transplantation; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Prednisolone; Transplantation, Homologous | 1975 |
Letter: Pericarditis in a case of early daunorubicin cardiomyopathy.
Topics: Acute Disease; Adult; Bacteriuria; Cardiomyopathies; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid; Pericarditis; Pseudomonas Infections | 1976 |
Acute leukemia in adults: comparison of survival between a treated and an untreated group.
Topics: Acute Disease; Adolescent; Adult; Aged; Child; Cyclophosphamide; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Middle Aged; Prednisone; Thioguanine; Thioinosine; Vincristine | 1976 |
[Current treatment and prognosis of chronic myeloid leukemia].
Topics: Adult; Aged; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Prednisone; Prognosis; Vincristine | 1976 |
Essential thrombocythemia developing into refractory anemia and complicated by acute myeloid leukemia.
Topics: Aged; Anemia, Refractory; Antineoplastic Combined Chemotherapy Protocols; Carbazilquinone; Cytarabine; Daunorubicin; Humans; Karyotyping; Leukemia, Myeloid; Male; Mercaptopurine; Prednisolone; Thrombocythemia, Essential | 1992 |
Serum soluble CD4, CD8 and IL-2R levels in adult acute myeloid leukemia in remission.
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; CD4 Antigens; CD8 Antigens; Cytarabine; Cytotoxicity, Immunologic; Daunorubicin; Female; Humans; Immunophenotyping; Interleukin-2; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Prednisolone; Remission Induction | 1992 |
Detection of activity of P-glycoprotein in human tumour samples using rhodamine 123.
Topics: Acute Disease; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Daunorubicin; Drug Resistance; Humans; Leukemia, Myeloid; Membrane Glycoproteins; Neoplasm Proteins; Rhodamine 123; Rhodamines; Tumor Cells, Cultured | 1992 |
Acute myeloid leukemia (AML) in Down's syndrome is highly responsive to chemotherapy: experience on Pediatric Oncology Group AML Study 8498.
Topics: Acute Disease; Adolescent; Adult; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Asparaginase; Azacitidine; Child; Chromosome Aberrations; Chromosome Disorders; Cytarabine; Daunorubicin; Down Syndrome; Etoposide; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Methotrexate; Prednisone; Remission Induction; Thioguanine; Vincristine | 1992 |
Comparative effects of G-CSF, GM-CSF and IL-3 on cytosine arabinoside- and daunorubicin-mediated cytotoxicity of acute myeloid leukemia cells and normal myeloid progenitors.
Topics: Acute Disease; Cell Survival; Colony-Stimulating Factors; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid; Reference Values; Stem Cells; Tumor Cells, Cultured | 1992 |
DAE (daunorubicin, Ara-C, and etoposide) and intermediate dose Ara-C for remission induction and consolidation treatment of adult patients with acute myeloid leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Survival Analysis | 1992 |
Differences in the intracellular pharmacokinetics of cytosine arabinoside (AraC) between circulating leukemic blasts and normal mononuclear blood cells.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; Arabinofuranosyluracil; Cytarabine; Daunorubicin; Drug Administration Schedule; Humans; Leukemia, Myeloid; Leukocytes, Mononuclear; Lymphoma, Non-Hodgkin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Thioguanine | 1992 |
[Pharmacokinetics and action mechanism of anthracyclines].
Topics: Aclarubicin; Acute Disease; Antibiotics, Antineoplastic; Daunorubicin; DNA; DNA Damage; DNA Replication; Doxorubicin; Humans; Leukemia, Myeloid | 1992 |
Is allogeneic bone marrow transplantation the best treatment for young adult patients with acute myeloid leukemia in first complete remission. The BGMT Group.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Combined Modality Therapy; Cytarabine; Daunorubicin; Drug Administration Schedule; Evaluation Studies as Topic; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Prospective Studies; Recurrence; Remission Induction; Transplantation, Homologous | 1992 |
Anthracyclines and their C-13 alcohol metabolites: growth inhibition and DNA damage following incubation with human tumor cells in culture.
Topics: Antibiotics, Antineoplastic; Cell Division; Daunorubicin; DNA Damage; DNA, Neoplasm; Doxorubicin; Epirubicin; Glioma; Humans; Idarubicin; Leukemia, Myeloid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured | 1992 |
Prognostic impact of karyotype and immunologic phenotype in 125 adult patients with de novo AML.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chromosome Aberrations; Cytarabine; Daunorubicin; Female; Humans; Immunophenotyping; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Remission Induction; Survival Analysis | 1992 |
Continuous-infusion daunorubicin and carboplatin for high-risk acute myeloid leukemia in the elderly.
Topics: Acute Disease; Age Factors; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Daunorubicin; Female; Humans; Infusions, Intravenous; Leukemia, Myeloid; Male; Middle Aged | 1992 |
Concomitant chronic lymphocytic leukemia (CLL) and acute myeloid leukemia. Complete remission of CLL achieved with high-dose cytosine arabinoside.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Female; Humans; Leukemia, B-Cell; Leukemia, Myeloid; Middle Aged; Neoplasms, Multiple Primary; Remission Induction | 1992 |
Pharmacological and physicochemical properties of a new anthracycline with potent antileukemic activity.
Topics: Animals; Antibiotics, Antineoplastic; Cell Division; Daunorubicin; DNA Topoisomerases, Type II; G2 Phase; Humans; Leukemia L1210; Leukemia, Experimental; Leukemia, Myeloid; Mice; Mitosis; Oxidation-Reduction | 1991 |
Endothelial expression of intercellular adhesion molecule (ICAM-1) is unaffected by marrow aplasia-inducing chemotherapy.
Topics: Amsacrine; Antigens, CD; Antineoplastic Agents; Bone Marrow; Cell Adhesion Molecules; Cytarabine; Daunorubicin; Endothelium; Humans; Intercellular Adhesion Molecule-1; Leukemia, Myeloid; Lymphocyte Function-Associated Antigen-1; Skin | 1991 |
Subcellular distribution of daunorubicin in P-glycoprotein-positive and -negative drug-resistant cell lines using laser-assisted confocal microscopy.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Daunorubicin; Drug Resistance; Fluorescence; Humans; Intracellular Fluid; Lasers; Leukemia, Experimental; Leukemia, Myeloid; Membrane Glycoproteins; Microscopy; Subcellular Fractions; Tumor Cells, Cultured | 1991 |
Daunorubicin impairs 1-beta-D-arabinofuranosylcytosine uptake.
Topics: Cytarabine; Daunorubicin; Humans; Kinetics; Leukemia, Myeloid; Tumor Cells, Cultured | 1991 |
Intensive individualized induction therapy with behenoyl cytarabine, daunorubicin and 6-mercaptopurine followed by intensive consolidation including intermediate-dose continuous cytarabine, mitoxantron, etoposide and vinca alkaloids in acute myeloid leuke
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Mitoxantrone; Vinca Alkaloids | 1991 |
Specific binding and internalization of monoclonal antibody HI98-daunorubicin conjugate by human leukemic cells (HL60).
Topics: Antibodies, Monoclonal; Daunorubicin; Humans; Immunotoxins; Leukemia, Myeloid; Microscopy, Immunoelectron; Tumor Cells, Cultured | 1991 |
[Controversies in the treatment of acute myeloid leukemia of the adult. Chemotherapy vs bone marrow transplantation].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Child; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid; Middle Aged | 1991 |
Involvement of vacuolar H(+)-adenosine triphosphatase activity in multidrug resistance in HL60 cells.
Topics: Anti-Bacterial Agents; Daunorubicin; Doxorubicin; Drug Resistance; Humans; Leukemia, Experimental; Leukemia, Myeloid; Macrolides; Proton-Translocating ATPases; Tritium; Tumor Cells, Cultured; Vacuoles; Vincristine | 1991 |
Recombinant human granulocyte-macrophage colony-stimulating factor after chemotherapy in patients with acute myeloid leukemia at higher age or after relapse.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Leukemia, Myeloid; Middle Aged; Mitoxantrone; Neutropenia; Recombinant Proteins; Remission Induction; Thioguanine | 1991 |
Restoration of daunomycin retention in multidrug-resistant P388 cells by submicromolar concentrations of SDZ PSC 833, a nonimmunosuppressive cyclosporin derivative.
Topics: Amiodarone; Animals; Cyclosporins; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance; Flow Cytometry; Leukemia, Experimental; Leukemia, Myeloid; Microscopy, Fluorescence; Quinacrine; Quinidine; Tumor Cells, Cultured; Verapamil | 1991 |
Post consolidation therapy for adult patients with acute myeloid leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Busulfan; Combined Modality Therapy; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Remission Induction; Thioguanine; Time Factors | 1991 |
Granulocytic sarcoma or large cell lymphoma?
Topics: Biopsy; Child, Preschool; Cyclophosphamide; Daunorubicin; Diagnosis, Differential; Etoposide; Female; Humans; Leukemia, Myeloid; Lymphoma, Large B-Cell, Diffuse; Magnetic Resonance Imaging; Methotrexate; Thiotepa; Vincristine | 1991 |
Nodular regenerative hyperplasia: a cause of ascites and hepatomegaly after chemotherapy for leukemia.
Topics: Abdominal Pain; Adult; Antineoplastic Combined Chemotherapy Protocols; Ascites; Biopsy; Cytarabine; Daunorubicin; Female; Hepatomegaly; Humans; Hyperplasia; Leukemia, Myeloid; Liver | 1991 |
Dysmegakaryopoiesis resembling acute megakaryoblastic leukemia in treated acute myeloid leukemia.
Topics: Acute Disease; Antigens, CD; Bone Marrow; Cytarabine; Daunorubicin; Diagnosis, Differential; Doxorubicin; Etoposide; Humans; Hyperplasia; Immunophenotyping; Leukemia, Megakaryoblastic, Acute; Leukemia, Myeloid; Megakaryocytes; Mitoxantrone; Myelodysplastic Syndromes; Prognosis; Time Factors | 1991 |
Circulating immune complexes correlate with remission duration in acute myeloid leukemia.
Topics: Adolescent; Adult; Aged; Antigen-Antibody Complex; Bone Marrow; Bone Marrow Cells; Complement C1q; Cytarabine; Cytotoxicity, Immunologic; Daunorubicin; Doxorubicin; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Prognosis; Prospective Studies; Remission Induction; Sex Factors; Survival Analysis | 1991 |
Chemotherapeutic drug sensitivity testing of human leukemia cells in vitro using a semiautomated fluorometric assay.
Topics: Cell Count; Cell Survival; Daunorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Fluoresceins; Fluorometry; Humans; Leukemia; Leukemia, Myeloid; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured; Vincristine | 1990 |
Intensive short-term chemotherapy for patients with acute myelogenous leukemia: long-term follow-up.
Topics: Actuarial Analysis; Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Bone Marrow; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Middle Aged; Pilot Projects; Thioguanine | 1985 |
Effects of cell density on drug-induced cell kill kinetics in vitro (inoculum effect).
Topics: Antineoplastic Agents; Bleomycin; Burkitt Lymphoma; Carboplatin; Cell Count; Cell Survival; Cisplatin; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Mitoxantrone; Organoplatinum Compounds; Vincristine | 1986 |
The value of intensive combination chemotherapy for juvenile chronic myelogenous leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Child, Preschool; Cytarabine; Daunorubicin; Etoposide; Female; Humans; Infant; Leukemia, Myeloid; Male; Mercaptopurine; Mitoxantrone; Thioguanine | 1987 |
Intracellular distribution and pharmacokinetics of daunorubicin in anthracycline-sensitive and -resistant HL-60 cells.
Topics: Antibiotics, Antineoplastic; Azides; Cell Line; Cell Nucleus; Cytoplasm; Daunorubicin; Deoxyglucose; Drug Resistance; Fluorescence; Golgi Apparatus; Leukemia, Myeloid; Mitochondria; Protons; Sodium Azide; Temperature | 1989 |
High-dose cytarabine and daunorubicin as consolidation therapy for acute myeloid leukemia in first remission: long-term follow-up and results.
Topics: Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Cytarabine; Daunorubicin; Female; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Middle Aged; Statistics as Topic | 1989 |
[New developments in chemotherapy for experimental brain metastasis].
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Brain Neoplasms; Daunorubicin; Doxorubicin; Floxuridine; Hydantoins; Leukemia, Myeloid; Liver Neoplasms, Experimental; Lomustine; Meningeal Neoplasms; Methotrexate; Neoplasm Transplantation; Nimustine; Nitrogen Mustard Compounds; Nitrosourea Compounds; Procarbazine; Rats | 1985 |
Enhancement by hemin of the sensitivity of K562 human leukemic cells to 1-beta-D-arabinofuranosylcytosine.
Topics: Aminolevulinic Acid; Butyrates; Cell Differentiation; Cell Line; Cytarabine; Daunorubicin; Deoxyguanosine; Doxorubicin; Drug Synergism; Erythropoiesis; Heme; Hemin; Humans; Hydroxyurea; Leukemia, Myeloid; Methotrexate; Thymidine; Vincristine | 1986 |
[An unusual way of manifesting acute granulocytic leukemia: granulocytic sarcoma of the breast. Apropos of a case with trisomy 22].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chromosomes, Human, 21-22 and Y; Cytarabine; Daunorubicin; Female; Granulocytes; Humans; Karyotyping; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Neoplasms, Multiple Primary; Trisomy | 1986 |
Preliminary observations on intravenous idarubicin (4-demethoxydaunorubicin) in the chronic and accelerated phase of chronic myelogenous leukemia.
Topics: Administration, Oral; Adult; Antibiotics, Antineoplastic; Daunorubicin; Female; Humans; Idarubicin; Leukemia, Myeloid; Leukocyte Count; Male; Middle Aged; Platelet Count | 1986 |
[Phase II trial of mitoxantrone in patients with relapsed and refractory acute leukemia].
Topics: Aclarubicin; Acute Disease; Adolescent; Adult; Aged; Blast Crisis; Child; Daunorubicin; Drug Evaluation; Drug Resistance; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Male; Middle Aged; Mitoxantrone; Naphthacenes | 1986 |
Differentiation therapy of a myelomonocytic leukemia (c-WRT-7) in rats by injection of lipopolysaccharide and daunomycin.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Differentiation; Daunorubicin; Leukemia, Myeloid; Lipopolysaccharides; Neoplasm Transplantation; Rats; Rats, Inbred Strains | 1987 |
Erythroid differentiation and modulation of c-myc expression induced by antineoplastic drugs in the human leukemic cell line K562.
Topics: Cell Differentiation; Cell Line; Cytarabine; Daunorubicin; DNA; Erythrocytes; Gene Expression Regulation; Globins; Humans; Leukemia, Myeloid; Proto-Oncogenes; RNA, Messenger | 1987 |
[A successful topical administration of prostaglandin E2 (PGE2) for the prophylaxis of chemotherapy associated oral mucosal lesions in a case of monocytic leukemia].
Topics: Administration, Topical; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Dinoprostone; Female; Humans; Leukemia, Myeloid; Mercaptopurine; Middle Aged; Mouth Mucosa; Prednisolone; Prostaglandins E; Stomatitis | 1987 |
Multipotent human hematopoietic cell line K562: lineage-specific constitutive and inducible antigens.
Topics: Antigens; Cell Differentiation; Daunorubicin; Erythrocytes; Granulocytes; Hematopoietic Stem Cells; Humans; Hypoxanthine; Hypoxanthines; Leukemia, Myeloid; Megakaryocytes; Monocytes; Thymidine; Tumor Cells, Cultured | 1987 |
[Daunomycin-induced cardiogenic shock in a case of acute myelogenous leukemia].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Prednisolone; Shock, Cardiogenic | 1987 |
[Therapy of patients with myeloid leukemia with small doses of cytosine arabinoside].
Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Daunorubicin; Drug Evaluation; Female; Humans; Injections, Intravenous; Injections, Subcutaneous; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Remission Induction | 1987 |
Contribution of drug transport and reductases to daunorubicin resistance in human myelocytic cells.
Topics: Adult; Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Biological Transport; Cell Line; Daunorubicin; Drug Resistance; Drug Synergism; Humans; Leukemia, Myeloid; Verapamil | 1986 |
Intensive combination chemotherapy (ROAP 10) and splenectomy in the management of chronic myelogenous leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chromosomes, Human, 21-22 and Y; Combined Modality Therapy; Cytarabine; Daunorubicin; Follow-Up Studies; Humans; Leukemia, Myeloid; Male; Middle Aged; Prednisone; Prognosis; Splenectomy; Translocation, Genetic; Vincristine | 1985 |
The blast crisis of chronic granulocytic leukaemia: a new approach to treatment.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid; Male; Middle Aged; Thioguanine | 1985 |
13-cis-Retinoic acid does not increase the true remission rate and the duration of true remission (induced by cytotoxic chemotherapy) in patients with chronic phase chronic myelogenous leukemia.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chromosomes, Human, 21-22 and Y; Cytarabine; Daunorubicin; Humans; Isotretinoin; Leukemia, Myeloid; Leukopenia; Liver; Middle Aged; Stomatitis; Thioguanine; Thrombocytopenia; Time Factors; Tretinoin | 1985 |
Acute myelomonocytic leukemia (M-4 subtype) with abnormal marrow eosinophilia and a normal chromosome 16.
Topics: Antigens, Surface; Bone Marrow; Chromosomes, Human, 16-18; Cytarabine; Daunorubicin; Eosinophilia; Humans; Leukemia, Myeloid; Male; Middle Aged; Pancytopenia | 1985 |
Hypercalcaemia in the accelerated phase of chronic myelogenous leukaemia: no relationship to the phenotype of the blast cells.
Topics: Adult; Bone Marrow Examination; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Hydroxyurea; Hypercalcemia; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Phenotype; Primary Myelofibrosis | 1985 |
Chronic myelogenous leukemia: a multivariate analysis of the associations of patient characteristics and therapy with survival.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; Basophils; Blood Cell Count; Body Weight; Bone Marrow Cells; Busulfan; Chromosome Aberrations; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Combinations; Female; Hemoglobins; Humans; Hydroxyurea; Leukemia, Myeloid; Male; Middle Aged; Philadelphia Chromosome; Prednisone; Prognosis; Risk; Vincristine | 1985 |
[Experimental studies on the therapy of rat myelomonocytic leukemia with lipopolysaccharide (LPS) and daunomycin (DM)].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Daunorubicin; Leukemia, Myeloid; Lipopolysaccharides; Rats; Rats, Inbred Strains | 1985 |
[Evaluation of the sensitivity to cytostatics of leukemia cells by labeling with tritiated thymidine and uridine: comparison with clinical response].
Topics: Cytarabine; Daunorubicin; Humans; Leukemia, Myeloid; Retrospective Studies; Tumor Stem Cell Assay | 1985 |
Uptake and metabolism of daunorubicin by human myelocytic cells.
Topics: Alcohol Oxidoreductases; Aldehyde Reductase; Aldo-Keto Reductases; Cell Line; Daunorubicin; Humans; Hydrogen-Ion Concentration; Isoelectric Focusing; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute | 1985 |
[A case of spinal chloroma revealing acute leukemia].
Topics: Adult; Asparaginase; Betamethasone; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Methotrexate; Spinal Cord Compression; Spinal Neoplasms | 1974 |
[Therapy of the blastic crisis].
Topics: Adolescent; Adult; Aged; Busulfan; Chromosome Aberrations; Daunorubicin; Female; Fever; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Prednisone; Splenomegaly; Time Factors | 1972 |
Daunorubicin. Results in childhood leukaemia.
Topics: Adolescent; Agranulocytosis; Anemia; Bone Marrow; Bone Marrow Cells; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Synergism; Female; Hemorrhage; Humans; Infant; Injections, Intravenous; Leukemia, Lymphoid; Leukemia, Myeloid; Male; Mercaptopurine; Neutrophils; Prednisolone; Thrombocytopenia; Vincristine | 1972 |
Chemotherapy through lysosomes with a DNA-daunorubicin complex.
Topics: Animals; Cells, Cultured; Daunorubicin; DNA; Drug Combinations; Injections, Intravenous; Leukemia, Experimental; Leukemia, Myeloid; Lysosomes; Mice; Mice, Inbred DBA; Mice, Inbred Strains; Pinocytosis; Protein Binding; Sarcoma, Experimental; Staphylococcus | 1972 |
Intensive chemotherapy of acute myelogenous leukaemia.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Cyclophosphamide; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Mercaptopurine; Middle Aged; Vincristine | 1972 |
Therapy of acute myelocytic leukemia. Daunomycin contrasted with a combination of cytosine arabinoside and 6-thioguanine.
Topics: Acute Disease; Adolescent; Adult; Aged; Cytarabine; Daunorubicin; Drug Combinations; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Remission, Spontaneous; Thioguanine | 1972 |
[Clinical studies on the early diagnosis and treatment of blastic crisis of chronic myelogenous leukemia].
Topics: Alkaline Phosphatase; Busulfan; C-Reactive Protein; Cytarabine; Daunorubicin; Female; Humans; Leukemia, Myeloid; Male; Mercaptopurine; Middle Aged; Prednisolone | 1972 |
High dose daunorubicin (NSC-83142) in the treatment of advanced acute myelogenous leukemia.
Topics: Adult; Child, Preschool; Daunorubicin; Female; Heart Diseases; Humans; Leukemia, Myeloid; Male; Phlebitis; Skin Ulcer | 1972 |
Daunorubicin in the therapy of acute granulocytic leukemia.
Topics: Adolescent; Adult; Age Factors; Aged; Blood Platelets; Blood Transfusion; Cytarabine; Daunorubicin; Female; Humans; Hydrazines; Hyperplasia; Leukemia, Myeloid; Leukocyte Count; Leukopenia; Male; Mercaptopurine; Methotrexate; Middle Aged; Remission, Spontaneous; Thrombocytopenia; Time Factors | 1973 |
Daunorubicin-prednisone remission induction with hydroxyurea maintenance in acute non-lymphocytic leukemia.
Topics: Adult; Age Factors; Daunorubicin; Female; Humans; Hydroxyurea; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphocyte Activation; Male; Prednisone; Remission, Spontaneous; Sex Factors | 1973 |
Leukemic infiltration of the optic nerve head.
Topics: Busulfan; Child; Daunorubicin; Edema; Female; Humans; Intracranial Pressure; Leukemia, Myeloid; Methotrexate; Optic Nerve; Papilledema; Pulmonary Embolism | 1973 |
Acute myeloid leukemia with two Philadelphia chromosomes in forty-six stemline. Remarks on the karyotypic analysis and chemotherapy.
Topics: Chromosome Aberrations; Chromosomes, Human, 21-22 and Y; Clone Cells; Cytogenetics; Daunorubicin; Diploidy; Humans; Karyotyping; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Mitosis; Prednisone; Time Factors; Vincristine | 1973 |
Treatment of acute myeloid leukaemia according to the Hammersmith protocol: preliminary report.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Cytarabine; Daunorubicin; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; London; Middle Aged; Prednisolone; Remission, Spontaneous; Thioguanine | 1973 |
[Acute myelogenous leukaemia of adults: diagnosis, prognosis and treatment (author's transl)].
Topics: Adult; Cytarabine; Daunorubicin; Diagnosis, Differential; Drug Evaluation; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Muramidase; Prognosis; Remission, Spontaneous; Thymidine; Tritium | 1973 |
In-vitro sensitivity to cytostatics in chronic myeloid leukaemia.
Topics: Antibiotics, Antineoplastic; Busulfan; Cells, Cultured; Cytotoxicity Tests, Immunologic; Daunorubicin; Drug Hypersensitivity; Humans; Hydroxyurea; Leukemia, Myeloid; Leukocytes; Mannitol; Mannomustine; Methotrexate | 1973 |
Acute granulocytic leukemia in elderly patients.
Topics: Adult; Age Factors; Aged; Bone Marrow Examination; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Remission, Spontaneous; Retrospective Studies; Time Factors | 1973 |
Eosinophilic leukaemia.
Topics: Aged; Chromosome Aberrations; Daunorubicin; Diagnosis, Differential; Eosinophils; Female; Humans; Leukemia; Leukemia, Myeloid | 1973 |
A case of acute myelomonocytic leukaemia associated with myelomatosis.
Topics: Aged; Autopsy; Blood Cell Count; Blood Protein Disorders; Blood Protein Electrophoresis; Bone Marrow; Bone Marrow Cells; Cytarabine; Daunorubicin; Humans; Immunoelectrophoresis; Immunoglobulin G; Leukemia, Myeloid; Male; Melphalan; Multiple Myeloma; Prednisone | 1973 |
[Therapeutical induced cytochemical changes in acute leukemia].
Topics: Adolescent; Adult; Aminosalicylic Acids; Asparaginase; Blood Cells; Bone Marrow; Bone Marrow Cells; Daunorubicin; Diagnosis, Differential; Doxorubicin; Esterases; Histocytochemistry; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Methotrexate; Middle Aged; Peroxidases; Prednisolone; Thioguanine; Vincristine | 1974 |
The treatment of acute myeliod leukaemia.
Topics: Adolescent; Adult; Blood Cell Count; Cytarabine; Daunorubicin; Drug Therapy, Combination; Humans; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Middle Aged; Remission, Spontaneous | 1974 |
Chronic granulocytic leukaemia: multiple-drug chemotherapy for acute transformation.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Asparaginase; Chromosome Aberrations; Chromosomes, Human, 21-22 and Y; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid; Male; Methotrexate; Middle Aged; Prednisolone; Thioguanine; Vincristine | 1974 |
Studies of leukemic cell populations in culture.
Topics: Autoradiography; Bone Marrow Cells; Cell Adhesion; Cell Division; Cell Separation; Cells, Cultured; Culture Media; Cytarabine; Daunorubicin; Freezing; Humans; Lectins; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Mercaptopurine; Middle Aged; Prednisone; Radiation Effects; Thymidine; Tritium; Ultrafiltration | 1974 |
[Parapromyelocytic leukemia. Case report].
Topics: Daunorubicin; Female; Humans; Leukemia, Myeloid; Middle Aged; Prognosis; Prothrombin Time | 1974 |
Letter: Myeloblastic transformation.
Topics: Asparaginase; Daunorubicin; Doxorubicin; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Vincristine | 1974 |
Recent results in acute leukemias at the Hospital Saint-Louis.
Topics: Adult; Age Factors; Child; Daunorubicin; Drug Evaluation; Drug Therapy, Combination; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Paris; Prednisone; Remission, Spontaneous; Time Factors; Vincristine | 1973 |
The evolution of the Ph1-trisomic clone, in a case of chronic myeloid leukemia.
Topics: Adult; Bone Marrow; Bone Marrow Cells; Cell Count; Chromosome Aberrations; Chromosomes, Human, 21-22 and Y; Clone Cells; Cyclophosphamide; Daunorubicin; Humans; Karyotyping; Leukemia, Myeloid; Male; Recurrence; Trisomy; Vincristine | 1974 |
The management of blastic crisis of chronic myeloid leukaemia with thioguanine, rubidomycin, ARA C and prednisone (TRAP regimen).
Topics: Adult; Aged; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Therapy, Combination; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Prednisone; Remission, Spontaneous; Thioguanine | 1973 |
[Chemotherapy of leukemia].
Topics: Acute Disease; Antineoplastic Agents; Asparaginase; Chronic Disease; Cyclophosphamide; Daunorubicin; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Prednisone; Vincristine | 1968 |
Urinary polyamines in cancer patients.
Topics: Brain Neoplasms; Chemistry, Clinical; Daunorubicin; Female; Hodgkin Disease; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Non-Hodgkin; Multiple Myeloma; Neoplasms; Ovarian Neoplasms; Polyamines; Pregnancy; Remission, Spontaneous; Spermidine; Spermine; Teratoma | 1971 |
[Studies of leukemia therapy with daunomycin].
Topics: Daunorubicin; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid | 1967 |
[Daunomycin].
Topics: Animals; Child; Child, Preschool; Daunorubicin; Dogs; Humans; In Vitro Techniques; Infant; Leukemia, Lymphoid; Leukemia, Myeloid; Mitosis; Neoplasms; Nucleic Acids; Rabbits; Rats | 1968 |
The effect of daunomycin on human cells in vivo and in vitro.
Topics: Aneuploidy; Bone Marrow; Bone Marrow Cells; Chromosome Aberrations; Culture Techniques; Daunorubicin; DNA, Neoplasm; Humans; Karyotyping; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocytes; RNA, Neoplasm | 1969 |
Treatment of AGL.
Topics: Adult; Afibrinogenemia; Aged; Anemia; Antineoplastic Agents; Child; Cytarabine; Daunorubicin; Humans; Hydroxyzine; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukopenia; Mercaptopurine; Methotrexate; Middle Aged; Polycythemia Vera; Prednisone; Primary Myelofibrosis; Splenomegaly; Vincristine | 1969 |
[Cytogenetic findings in chronic myeloid leukemia in childhood].
Topics: Child; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Chromosomes, Human, 21-22 and Y; Daunorubicin; Female; Humans; Leukemia, Myeloid | 1969 |
[Combination treatment of acute leukemia in the child with dauno-rubidomycin].
Topics: Asparaginase; Bone Marrow; Bone Marrow Cells; Child; Daunorubicin; Female; Humans; Injections, Intravenous; Leukemia, Lymphoid; Leukemia, Myeloid; Leukocyte Count; Prednisone; Vincristine | 1969 |
Daunorubicin in the treatment of adult acute leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Chromosome Aberrations; Daunorubicin; Female; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Middle Aged; Prednisolone; Thrombocytopenia; Vincristine | 1970 |
The potentiality of out-of-cycle acute leukemic cells to synthesize DNA.
Topics: Adult; Aged; Autoradiography; Child; Cyclophosphamide; Daunorubicin; DNA Replication; Female; Humans; Infant; Leukemia, Lymphoid; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocytes; Male; Methotrexate; Middle Aged; Prednisone; Radiation Effects; Thymidine; Tritium; Ultraviolet Rays; Vincristine | 1970 |
Therapy of acute leukemia.
Topics: Adolescent; Animals; Antineoplastic Agents; Asparaginase; Bone Marrow; Bone Marrow Cells; Child; Cytarabine; Daunorubicin; Disease Models, Animal; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Mercaptopurine; Methotrexate; Mice; Remission, Spontaneous; Vincristine | 1970 |
The effects of chemotherapeutic agents on the RNA metabolism of 90Sr-induced rat chloroleukemia.
Topics: Animals; Asparaginase; Cytarabine; Daunorubicin; Depression, Chemical; Hydrocortisone; In Vitro Techniques; Leukemia, Myeloid; Leukemia, Radiation-Induced; Poly I-C; Polynucleotides; Rats; RNA, Neoplasm; Strontium Isotopes; Tritium; Uridine; Vinblastine | 1971 |
[Round table conference--present status and the future of treatment of leukemia].
Topics: Acute Disease; Asparaginase; Cytarabine; Daunorubicin; Glutaminase; Humans; Leukemia; Leukemia, Myeloid; Vinblastine; Vincristine | 1971 |
[Progress in the therapy of leukoses].
Topics: Antineoplastic Agents; Azathioprine; Busulfan; Chlorambucil; Cyclophosphamide; Daunorubicin; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Mannitol; Methotrexate; Mitomycins; Triethylenemelamine; Vincristine | 1970 |