daunorubicin has been researched along with Breast Neoplasms in 142 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 55 (38.73) | 18.7374 |
| 1990's | 34 (23.94) | 18.2507 |
| 2000's | 31 (21.83) | 29.6817 |
| 2010's | 16 (11.27) | 24.3611 |
| 2020's | 6 (4.23) | 2.80 |
| Authors | Studies |
|---|---|
| Atassi, G; Baron, M; Bissery, MC; Cros, S; Gebel-Servolles, P; Giorgi-Renault, S; Lavelle, F; Paoletti, C; Renault, J | 1 |
| Bates, S; Litman, T; Nagy, Z; Ozvegy, C; Sarkadi, B; Szakács, G; Váradi, A | 1 |
| Aali, E; Darzi, S; Elahian, F; Mirzaei, SA; Peymani, A; Pishkhan Dibazar, S; Rahmani, B; Shakeri Chaleshtori, L; Shirian, S | 1 |
| Alrbyawi, H; Annaji, M; Arnold, RD; Babu, RJ; Boddu, SHS; Mita, N; Poudel, I; Tiwari, AK | 1 |
| Cai, FY; Fu, M; Gong, XQ; Jing, M; Ju, RJ; Kong, L; Li, XT; Liu, JJ; Tang, W; Yao, XM | 1 |
| Fossati, G; Kapuvári, B; Mező, G; Ranđelović, I; Schuster, S; Steinkühler, C; Tóvári, J | 1 |
| Abbas, M; Ahsan, A; Ansari, MT; Baig, MMFA; Farooq, MA; Jabeen, M; Kassim, SA; Khan, GJ; Lai, WF; Mikrani, R; Naveed, M | 1 |
| Cai, FY; Fu, M; He, SY; Jing, M; Ju, RJ; Kong, L; Li, XT; Liu, JJ; Liu, XZ; Niu, FJ; Yao, XM; Zhang, L | 1 |
| Andrews, C; Maze, D; Murphy, T; Sibai, H | 1 |
| Cheng, L; Ju, RJ; Li, CQ; Li, XT; Liu, S; Peng, XM; Qiu, X; Song, XL; Wang, T | 1 |
| Chao, JP; Cheng, L; Ju, RJ; Li, CQ; Li, XT; Liu, S; Peng, XM; Song, XL; Wang, T | 1 |
| Hayakawa, A; Hirano, T; Kiyomi, A; Onda, K; Sugiura, M; Sugiyama, K; Takagi, N; Tanaka, S; Uematsu, N; Yuan, BO; Zhao, Y | 1 |
| Andreu, D; Hegedüs, R; Manea, M; Marquardt, A; Mező, G; Orbán, E; Pauschert, A; Szabó, I | 1 |
| Bonkovsky, HL; D'Agostino, RB; Hundley, WG; Jordan, JH; Lamar, ZS; Meléndez, GC; Poole, LB; Porosnicu, M; Vera, T; Whitlock, MC | 1 |
| Cheng, L; Li, XT; Liu, S; Song, XL; Wang, X; Wang, XM; Wang, YH; Xiao, Y | 1 |
| Baubion, N; Buzyn, A; Decaudin, D; Delarue, R; Fourquet, A; Ghez, D; Hermine, O; Messas, E; Rubio, MT; Suarez, F; Varet, B; Willems, L | 1 |
| Ha, I; Han, HK; Im, YB; Kang, KW; Lee, MY | 1 |
| Chao, TY; Huang, TC | 1 |
| Du, J; Guo, J; Ju, RJ; Li, RJ; Lu, WL; Men, Y; Tian, W; Wang, XX; Yao, HJ; Ying, X; Zhang, Y; Zhou, J | 1 |
| Chen, JX; Ju, RJ; Li, N; Li, RJ; Lu, WL; Men, Y; Tian, W; Wang, XX; Yao, HJ; Ying, X; Yu, Y; Zhang, L; Zhang, Y; Zhou, J | 1 |
| Edwards, K; Fondell, A; Gedda, L; Kullberg, E; Park, JW; Unga, J | 1 |
| Bosze, S; Manea, M; Mezo, G; Orbán, E; Schlage, P | 1 |
| Ju, RJ; Li, RJ; Lu, WL; Shi, JF; Sun, MG; Wang, XX; Yao, HJ; Yu, Y; Zhang, L; Zhang, Y | 1 |
| Kim, I; Oh, B; Pak, JH; Park, S | 1 |
| Howard, GP; Master, AM; Modery-Pawlowski, CL; Pan, V; Sen Gupta, A | 1 |
| Chauvier, D; Kegelaer, G; Manfait, M; Morjani, H | 1 |
| Coleman, A; Kane, SE; Sadava, D | 1 |
| Bengala, C; Biadi, O; Conte, PF; Danesi, R; Del Tacca, M; Donati, S; Favre, C; Fogli, S; Guarneri, V; Innocenti, F; Mariani, M; Pazzagli, I | 1 |
| Balázs, B; Falus, A; Hudecz, F; Reményi, J; Tóth, G; Tóth, S | 1 |
| Rivera, E | 1 |
| O'Shaughnessy, J | 1 |
| Campos, S | 1 |
| Herrmann, A; Lage, H; Osada, H; Woehlecke, H | 1 |
| Damon, L; Demirer, T; Derigs, G; Ferrante, P; Kröger, N; Rosti, G; Wandt, H; Zander, AR | 1 |
| Boronovskaia, LE; Korman, DB; Maslova, IA; Mikaélian, SG | 1 |
| de Jong, MC; Greijer, AE; Scheffer, GL; Shvarts, A; van der Wall, E; van Diest, PJ | 1 |
| Abdul-Ghani, R; Dietel, M; Garber, M; Györffy, B; Jürchott, K; Lage, H; Petersen, I; Schäfer, R; Serra, V; Stein, U | 1 |
| Chung, SY; Go, EJ; Jang, JO; Kim, NH; Lee, HJ; Sung, MK | 1 |
| Barbara, C; Bocci, G; Danesi, R; Del Tacca, M; Di Paolo, A; Fioravanti, A; Orlandi, P | 1 |
| Corona, G; Crivellari, D; Lestuzzi, C; Lombardi, D; Lucenti, A; Magri, MD; Massacesi, C; Sorio, R; Talamini, R; Toffoli, G; Veronesi, A | 1 |
| Azzariti, A; Berardi, F; Colabufo, NA; Niso, M; Paradiso, A; Perrone, R; Porcelli, L; Simone, GM | 1 |
| Fan, E; Lowary, TL; Shi, W | 1 |
| Budach, W | 1 |
| Ghoneum, M; Gollapudi, S | 1 |
| Jollès, G; Trouet, A | 1 |
| Danova, LA; Gershanovich, ML; Trishkina, EA | 1 |
| Carter, SK | 1 |
| Crespeigne, N; Decoster, G; Kenis, Y; Klastersky, J; Rombaut, W; Rozencweig, M; Sanders, C | 1 |
| de Planque, MM; Lankelma, J; McVie, JG; Pinedo, HM; Ten Bokkel Huinink, WW; Weenen, H | 1 |
| Aboud, A; Blumenschein, GR; Bodey, GP; Esparza, L; Hortobagyi, G; Issell, B; Yap, HY | 1 |
| Bramwell, V; Bruntsch, U; Cavalli, F; Decoster, G; Dombernowsky, P; Høst, H; Renard, G; Rozencweig, M; ten Bokkel Huinink, W; Van Glabbeke, M | 1 |
| Nissen, E; Redmann, K; Schälike, W; Tanneberger, S | 1 |
| Athens, JW; Baker, LH; Foulkes, M; Gad-el-Mawla, N; Panettiere, FJ; Smith, FE; Tranum, B | 1 |
| Danova, LA; Gershanovich, ML; Labkovskiĭ, BM; Pavlov, KA; Trishkina, EA | 1 |
| de Planque, MM; Lankelma, J; Leyva, A; McVie, JG; Penders, PG; Pinedo, HM; Ten Bokkel-Huinink, WW | 1 |
| Myers, CE; Ozols, RF; Young, RC | 1 |
| Cornblatt, B; Doyle, LA; Ross, DD; Tong, Y; Yang, W | 1 |
| Chu, TM; Kawinski, E; Lin, TH | 1 |
| Barhamand, B | 1 |
| Barron, JT; Ghalie, R; Kaizer, H; Kakavas, PW; Parrillo, JE | 1 |
| Berlion, M; Dieterlen, A; Lucas, C; Marchal, S; Merlin, JL; Poullain, MG; Ramacci, C; Schultz, G | 1 |
| Fine, RL; Harrison, SD; Sachs, CW; Safa, AR | 1 |
| Lucas, C; Marchal, S; Merlin, JL; Paraire, M; Poullain, MG; Ramacci, C | 1 |
| Doyle, LA; Fojo, AT; Kaufmann, SH; Lee, EJ; Ross, DD; Schiffer, CA; Sridhara, R | 1 |
| Colomb, E; Martin, PM | 1 |
| Ikeda, K; Kubota, Y; Murata, M; Nagai, M; Ohnishi, H; Sasaki, K; Takahara, J; Tanaka, T; Taoka, T; Tasaka, T | 1 |
| Krishan, A | 1 |
| Amley, J; Chan, PK; Koller, CA; Qi, Y | 1 |
| Abderrabi, M; Marchal, S; Merlin, JL | 1 |
| Horikawa, K; Okada, Y; Sano, M | 1 |
| Altenberg, G; Bates, SE; Dickstein, B; Lee, JS; Matsumoto, Y; Robey, R; Scala, S; Zhan, Z | 1 |
| Forman, SJ; Margolin, KA; Wright, C | 1 |
| Elliott, RL; Head, JF; Wang, F | 1 |
| Benderra, Z; Manfait, M; Morjani, H; Trussardi, A | 1 |
| Fukuda, H; Kunitoh, H; Saijo, N; Sekine, I | 1 |
| Bates, SE; Blumberg, PM; Dickstein, B; Regis, J; Scala, S; Szallasi, Z | 1 |
| Abruzzo, LV; Doyle, LA; Gao, Y; Krogmann, T; Rishi, AK; Ross, DD; Yang, W | 1 |
| Cory, AH; Cory, JG; Hall, JG | 1 |
| Harrington, DJ; Koch, TH; Podell, ER; Taatjes, DJ | 1 |
| Afanas'ev, BV; Darskaia, EI; Zubarovskaia, LS | 1 |
| Komi, J; Lassila, O | 1 |
| Benderra, Z; Doglia, SM; Manfait, M; Morjani, H; Trussardi, A; Villa, AM | 1 |
| Iffert, T; Maser, E; Moeller, A; Soldan, M | 1 |
| Bierbaum, VM; Burke, PJ; Fenick, DJ; Kato, S; Koch, TH; Taatjes, DJ | 1 |
| Aita, P; Bearz, A; Boiocchi, M; Colussi, AM; Corona, G; Crivellari, D; Robieux, I; Sorio, R; Stocco, F; Toffoli, G | 1 |
| Bour-Dill, C; Giroux, B; Marchal, S; Merlin, JL; Poullain, MG; Ramacci, C | 1 |
| Muggia, FM | 1 |
| Gilbert, J; Haber, M; Madafiglio, J; Marshall, GM; Norris, MD | 1 |
| Beare, S; DeCatris, M; O'Byrne, KJ; Sharma, RA; Shields, F; Steward, WP; Thomas, AL | 1 |
| Chauvier, D; Manfait, M; Morjani, H | 1 |
| Hinderer, H; Kaufmann, M; Mattern, J; Volm, M; Wayss, K | 1 |
| Brucksch, KP; Schmidt, CG; Seeber, B; Seeber, S | 1 |
| Aoki, N; Kawada, K; Matsumoto, K; Taya, T | 1 |
| Benjamin, RS; Keating, MJ; Legha, S; McCredie, KB; Swenerton, KD | 1 |
| Benjamin, RS | 1 |
| Benjamin, RS; Blumenschein, GR; Buzdar, AU; Hortobagyi, GN; Legha, SS | 1 |
| Davis, HL; Davis, TE | 1 |
| Carpentier, Y; Desoize, B; Gorisse, MC | 1 |
| Diatchkovskaya, RF; Ganieva, LKh; Konovalova, NP; Lapshin, IM; Shapiro, AB; Volkova, LM | 1 |
| Colomb, E; Dussert, C; Martin, PM | 1 |
| Abe, O; Asanuma, F; Ishibiki, K; Josui, K; Kawamura, E; Koh, J; Kubota, T; Shiina, E; Suto, A; Yamada, Y | 1 |
| Atwell, J; Politi, PM; Sinha, BK | 1 |
| Arancia, G; Calcabrini, A; Crateri, P; Molinari, A | 1 |
| Majima, H | 1 |
| Amadori, D; Dollbaum, C; Hackett, AJ; Hiller, A; Lippman, M; Mayall, B; Smith, HS; Swain, S; Volpi, A; Zoli, W | 1 |
| Collins, C; Dusre, L; Myers, CE; Sinha, BK | 1 |
| Batomunkueva, TV; Korman, DB; Krutova, TV | 1 |
| Bastholt, L; Dalmark, M; Ebbehøj, E; Elbaek, K; Jakobsen, A; Juul, P; Rasmussen, SN; Steiness, E | 1 |
| Aboud-Pirak, E; Baurain, R; Lesur, B; Rao, KS; Schneider, YJ; Trouet, A | 1 |
| Raymond, V; Young, CW | 1 |
| Dodion, P; Kenis, Y; Kitt, MM; Klastersky, J; Rombaut, W; Rozencweig, M; Sanders, C | 1 |
| Cavalli, F; Gundersen, S; Renard, J; Sessa, C; ten Bokkel Huinink, W | 1 |
| Edmonson, JH; Ingle, JN; Long, HJ; Loprinzi, CL; Schaid, DJ; Schutt, AJ | 1 |
| Brandi, M; De Lena, M; Logroscino, A; Lorusso, V; Maiello, E; Paradiso, A | 1 |
| Bozzi, D; Brandi, M; Calabrese, P; De Lena, M; Romito, S | 1 |
| Blackledge, GR; Cullen, MH; Priestman, TJ; Stuart, NS; Tyrrell, CJ | 1 |
| Boulé, D; Fourcade, A; Lampidis, TJ; Tapiero, H; Trincal, G | 1 |
| Kolarić, K; Mechl, Z; Potrebica, V; Sopkova, B; Vukas, D | 1 |
| Angelelli, B; Camaggi, CM; Comparsi, R; Pacciarini, MA; Pannuti, F; Strocchi, E | 1 |
| Di Lauro, L; Di Pietro, N; Ganzina, F; Lazzaro, B; Lopez, M; Papaldo, P | 1 |
| Bourguignat, A; Eydoux, P; Floiras, JL; Le Doussal, V; Trassard, M; Turpin, F | 1 |
| Amoroso, D; Conte, PF; Lionetto, R; Pronzato, P; Rosso, R; Sertoli, MR | 1 |
| Bonadonna, G; Bonfante, V; Brambilla, C; Crippa, F; Ferrari, L; Rossi, A; Valagussa, P; Villani, F | 1 |
| Bastholt, L; Dalmark, M | 1 |
| Howell, A; Lucas, SB; Margison, JM; Smith, DB; Wilkinson, PM | 1 |
| Kolarić, K; Mechl, Z; Potrebica, V; Sopkova, B | 1 |
| Howell, A; Smith, DB | 1 |
| Casper, ES; Currie, VE; Hakes, TB; Kaufman, RJ; Raymond, V | 1 |
| Di Pietro, N; Ganzina, F; Pacciarini, MA | 1 |
| Meyer, D; Nagel, GA; Schuff-Werner, P; Wander, HE | 1 |
| Davila, E; Krishan, A; Sridhar, KS; Sternheim, W; Vogel, C | 1 |
| Cocconi, G; Mouridsen, HT; Paridaens, R; Rotmensz, N; Sylvester, R; Van Oosterom, AT; Wildiers, J | 1 |
| Martoni, A; Pacciarini, MA; Pannuti, F | 2 |
| Frei, E; Lokich, JJ; Skarin, AT | 1 |
| Duttera, MJ; Geelhoed, GW; Graff, KS; Henderson, ES | 1 |
| Hobson, RW; Kingry, RL; Muir, RW | 1 |
| Sutton, ML | 1 |
15 review(s) available for daunorubicin and Breast Neoplasms
| Article | Year |
|---|---|
Combination of targeted daunorubicin liposomes and targeted emodin liposomes for treatment of invasive breast cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Daunorubicin; Drug Delivery Systems; Emodin; Female; Humans; Liposomes; Mice; Neoplasm Invasiveness; Particle Size | 2020 |
Combination treatment with CPX-351 and midostaurin in patients with secondary acute myeloid leukaemia that are FLT3 mutated: three cases and review of literature.
Topics: Aged; Allografts; Anemia, Refractory, with Excess of Blasts; Aniline Compounds; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Breast Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; Clinical Trials, Phase III as Topic; Cytarabine; Daunorubicin; Fatal Outcome; Female; fms-Like Tyrosine Kinase 3; Humans; Leukemia, Myeloid, Acute; Liposomes; Male; Middle Aged; Myelodysplastic Syndromes; Neoplasm, Residual; Neoplasms, Radiation-Induced; Oncogene Proteins, Fusion; Peripheral Blood Stem Cell Transplantation; Point Mutation; Protein Kinase Inhibitors; Pyrazines; Remission Induction; Salvage Therapy; Staurosporine; Sulfonamides | 2020 |
Liposomal anthracyclines in metastatic breast cancer: clinical update.
Topics: Anthracyclines; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Daunorubicin; Doxorubicin; Heart Diseases; Humans; Liposomes; Neoplasm Metastasis; Paclitaxel | 2003 |
Liposomal anthracyclines for breast cancer: overview.
Topics: Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Daunorubicin; Doxorubicin; Heart Failure; Humans; Liposomes; Neoplasm Metastasis; Paclitaxel | 2003 |
Liposomal anthracyclines: adjuvant and neoadjuvant therapy for breast cancer.
Topics: Alopecia; Anthracyclines; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Daunorubicin; Doxorubicin; Heart Diseases; Humans; Liposomes; Nausea; Neoadjuvant Therapy; Risk Factors | 2003 |
Secondary acute leukemia following mitoxantrone-based high-dose chemotherapy for primary breast cancer patients.
Topics: Acute Disease; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow Transplantation; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Cytarabine; Daunorubicin; Doxorubicin; Epirubicin; Female; Humans; Incidence; Leukemia, Myeloid; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Leukemia, Radiation-Induced; Lymphatic Metastasis; Melphalan; Middle Aged; Mitoxantrone; Neoplasms, Second Primary; Paclitaxel; Peripheral Blood Stem Cell Transplantation; Radiotherapy, Adjuvant; Thiotepa; Transplantation Conditioning; Transplantation, Autologous | 2003 |
Targeting of daunorubicin by association with DNA or proteins: a review.
Topics: Animals; Antibiotics, Antineoplastic; Antibodies; Breast Neoplasms; Carcinoma, Hepatocellular; Daunorubicin; DNA; Heart; Humans; Liver Neoplasms; Naphthacenes; Proteins; Serum Albumin | 1984 |
New cytotoxic drugs for breast cancer and their clinical evaluation.
Topics: Altretamine; Aminoacridines; Amsacrine; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Daunorubicin; Doxorubicin; Female; Gallium; Humans; Ifosfamide; Leukemia; Vinblastine; Vindesine; Zinostatin | 1980 |
The anthracycline antineoplastic drugs.
Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Breast Neoplasms; Carubicin; Daunorubicin; Doxorubicin; Female; Glycosides; Hodgkin Disease; Humans; Leukemia; Lung Neoplasms; Lymphoma; Naphthacenes; Ovarian Neoplasms; Sarcoma | 1981 |
Cancer chemotherapy in the elderly.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Anthraquinones; Antineoplastic Agents; Breast Neoplasms; Busulfan; Daunorubicin; Doxorubicin; Etoposide; Female; Fluorouracil; Heart; Hematologic Neoplasms; Humans; Lung; Male; Middle Aged; Neoplasms; Pyrazoles | 1998 |
Liposomal encapsulated anthracyclines: new therapeutic horizons.
Topics: Acquired Immunodeficiency Syndrome; Antibiotics, Antineoplastic; Breast Neoplasms; Daunorubicin; Doxorubicin; Female; Humans; Leukemia; Liposomes; Lymphoma; Multiple Myeloma; Ovarian Neoplasms; Sarcoma, Kaposi | 2001 |
Adriamycin and other anthracycline antibiotics under study in the United States.
Topics: Antibiotics, Antineoplastic; Breast Neoplasms; Daunorubicin; Doxorubicin; Drug Combinations; Hodgkin Disease; Humans; Leukemia; Neoplasm Metastasis; Neoplasms; Soft Tissue Neoplasms; United States | 1978 |
Daunorubicin and adriamycin in cancer treatment: an analysis of their roles and limitations.
Topics: Breast Neoplasms; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Hodgkin Disease; Humans; Leukemia; Lymphoma; Neoplasms; Sarcoma; Soft Tissue Neoplasms | 1979 |
Clinical assessment of the structure-activity relationship of anthracyclines and related synthetic derivatives.
Topics: Aclarubicin; Anthraquinones; Antibiotics, Antineoplastic; Breast Neoplasms; Carubicin; Cell Survival; Daunorubicin; Doxorubicin; Drug Evaluation; Epirubicin; Heart; Humans; Idarubicin; Leukemia; Menogaril; Mitoxantrone; Naphthacenes; Nogalamycin; Sarcoma; Structure-Activity Relationship | 1986 |
Idarubicin (4-demethoxydaunorubicin). A preliminary overview of preclinical and clinical studies.
Topics: Administration, Oral; Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Daunorubicin; Drug Administration Schedule; Drug Evaluation; Drug Evaluation, Preclinical; Humans; Idarubicin; Infusions, Parenteral; Kinetics; Leukemia | 1986 |
12 trial(s) available for daunorubicin and Breast Neoplasms
| Article | Year |
|---|---|
[Results of a phase I-II clinical trial of Emoxyl, a novel antineoplastic anthracycline].
Topics: Aged; Anthracyclines; Antibiotics, Antineoplastic; Breast Neoplasms; Carcinoma, Small Cell; Daunorubicin; Drug Administration Schedule; Female; Humans; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Middle Aged; Neoplasms; Sarcoma, Kaposi; Treatment Outcome | 2004 |
Innovative schedule of oral idarubicin in elderly patients with metastatic breast cancer: comprehensive results of a phase II multi-institutional study with pharmacokinetic drug monitoring.
Topics: Administration, Oral; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Bone Neoplasms; Breast Neoplasms; Chromatography, High Pressure Liquid; Daunorubicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Monitoring; Female; Humans; Idarubicin; Liver Neoplasms; Lung Neoplasms; Soft Tissue Neoplasms | 2006 |
[Results of a clinical study of carminomycin in primary disseminated forms, recurrences and metastases of breast cancer].
Topics: Adult; Aged; Breast Neoplasms; Carubicin; Clinical Trials as Topic; Daunorubicin; Female; Humans; Injections, Intravenous; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Time Factors | 1983 |
New cytotoxic drugs for breast cancer and their clinical evaluation.
Topics: Altretamine; Aminoacridines; Amsacrine; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Daunorubicin; Doxorubicin; Female; Gallium; Humans; Ifosfamide; Leukemia; Vinblastine; Vindesine; Zinostatin | 1980 |
Randomized phase II trial of carminomycin versus 4'-epidoxorubicin in advanced breast cancer.
Topics: Adult; Aged; Alopecia; Breast Neoplasms; Carubicin; Daunorubicin; Doxorubicin; Drug Evaluation; Epirubicin; Female; Follow-Up Studies; Heart Diseases; Humans; Leukopenia; Middle Aged; Nausea; Neoplasm Metastasis; Random Allocation; Vomiting | 1984 |
Clinical controlled trial in advanced breast cancer: CMFV (cyclophosphamide, methotrexate, fluorouracil, vincristine) verus CD (carminomycin, dibromodulcitol).
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carubicin; Clinical Trials as Topic; Cyclophosphamide; Daunorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Mitolactol; Vincristine | 1982 |
[Administration of liposomal preparation of DaunoXome for breast cancer in patients with poor prognosis].
Topics: Adult; Antibiotics, Antineoplastic; Breast Neoplasms; Daunorubicin; Drug Carriers; Female; Humans; Liposomes; Middle Aged; Neoplasm Staging; Treatment Outcome | 1999 |
Dose-finding and pharmacologic study of chronic oral idarubicin therapy in metastatic breast cancer patients.
Topics: Administration, Oral; Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Breast Neoplasms; Cyclophosphamide; Daunorubicin; Docetaxel; Dose-Response Relationship, Drug; Doxorubicin; Epirubicin; Female; Fluorouracil; Humans; Idarubicin; Maximum Tolerated Dose; Methotrexate; Middle Aged; Neoplasm Metastasis; Paclitaxel; Taxoids; Time Factors | 2000 |
A phase I dose-escalating study of DaunoXome, liposomal daunorubicin, in metastatic breast cancer.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Breast Neoplasms; Daunorubicin; Dose-Response Relationship, Drug; Female; Fever; Humans; Infusions, Intravenous; Liposomes; Middle Aged; Neoplasm Metastasis; Neutropenia; Treatment Outcome | 2002 |
Rubidazone in metastatic breast cancer.
Topics: Adult; Breast Neoplasms; Clinical Trials as Topic; Daunorubicin; Female; Humans; Middle Aged; Neoplasm Metastasis | 1979 |
Carminomycin versus doxorubicin in advanced breast cancer, a randomized phase II study of the E.O.R.T.C. Breast Cancer Cooperative Group.
Topics: Adult; Aged; Breast Neoplasms; Carubicin; Daunorubicin; Doxorubicin; Drug Evaluation; Female; Humans; Leukocyte Count; Middle Aged; Platelet Count; Random Allocation | 1986 |
The new anthracycline 4-demethoxydaunorubicin by oral route in advanced pretreated breast cancer and melanoma. A pilot study.
Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Clinical Trials as Topic; Daunorubicin; Drug Evaluation; Female; Humans; Idarubicin; Leukopenia; Male; Melanoma; Middle Aged; Nausea; Vomiting | 1985 |
116 other study(ies) available for daunorubicin and Breast Neoplasms
| Article | Year |
|---|---|
Heterocyclic quinones. 17. A new in vivo active antineoplastic drug: 6,7-bis(1-aziridinyl)-4-[[3-(N,N-dimethylamino)propyl]amino]-5,8- quinazolinedione.
Topics: Animals; Antineoplastic Agents; Aziridines; Breast Neoplasms; Cell Division; Cell Line; Drug Screening Assays, Antitumor; Female; Humans; Leukemia L1210; Leukemia, Experimental; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Molecular Structure; Neoplasms, Experimental; Quinazolines; Sarcoma, Experimental; Structure-Activity Relationship | 1991 |
Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Membrane; Cloning, Molecular; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Neoplasm Proteins; Recombinant Proteins; Spodoptera; Tumor Cells, Cultured | 2001 |
Improvement of cytotoxicity of mitoxantrone and daunorubicin by candidone, tephrosin, and bavachinin.
Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Cytotoxins; Daunorubicin; Female; Flavonoids; Humans; MCF-7 Cells; Mitoxantrone; Neoplasm Proteins; Rotenone; Stomach Neoplasms | 2021 |
Cardiolipin for Enhanced Cellular Uptake and Cytotoxicity of Thermosensitive Liposome-Encapsulated Daunorubicin toward Breast Cancer Cell Lines.
Topics: Breast Neoplasms; Cardiolipins; Cholesterol; Daunorubicin; Female; Humans; Lipid Bilayers; Liposomes; MCF-7 Cells; Phosphorylcholine; Polyethylene Glycols | 2022 |
Improved In Vivo Anti-Tumor and Anti-Metastatic Effect of GnRH-III-Daunorubicin Analogs on Colorectal and Breast Carcinoma Bearing Mice.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Daunorubicin; Disease Models, Animal; Female; Gene Expression; Gonadotropin-Releasing Hormone; Humans; Male; Mice; Molecular Structure; Pyrrolidonecarboxylic Acid; Receptors, Cell Surface; RNA, Messenger; Toxicity Tests; Xenograft Model Antitumor Assays | 2019 |
Synthetic NRG-1 functionalized DNA nanospindels towards HER2/neu targets for in vitro anti-cancer activity assessment against breast cancer MCF-7 cells.
Topics: Antibiotics, Antineoplastic; Apoptosis; Breast Neoplasms; Cell Proliferation; Cell Survival; Daunorubicin; DNA; Drug Delivery Systems; Female; Flow Cytometry; Humans; MCF-7 Cells; Nanostructures; Neuregulin-1; Particle Size; Receptor, ErbB-2 | 2020 |
GGP modified daunorubicin plus dioscin liposomes inhibit breast cancer by suppressing epithelial-mesenchymal transition.
Topics: Breast Neoplasms; Cell Line, Tumor; Daunorubicin; Diosgenin; Epithelial-Mesenchymal Transition; Humans; Liposomes | 2020 |
Hyaluronic acid modified daunorubicin plus honokiol cationic liposomes for the treatment of breast cancer along with the elimination vasculogenic mimicry channels.
Topics: Animals; Biphenyl Compounds; Breast Neoplasms; Cations; Daunorubicin; Female; Humans; Hyaluronic Acid; Lignans; Liposomes; MCF-7 Cells; Mice; Neovascularization, Pathologic | 2018 |
Octreotide-modified liposomes containing daunorubicin and dihydroartemisinin for treatment of invasive breast cancer.
Topics: Ammonium Sulfate; Animals; Artemisinins; Biological Transport; Breast Neoplasms; Cell Movement; Daunorubicin; Humans; Lipid Bilayers; Liposomes; MCF-7 Cells; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Octreotide; Polyethylene Glycols; Wound Healing; Xenograft Model Antitumor Assays | 2018 |
Chemo-sensitivity of Two-dimensional Monolayer and Three-dimensional Spheroid of Breast Cancer MCF-7 Cells to Daunorubicin, Docetaxel, and Arsenic Disulfide.
Topics: Antineoplastic Agents; Arsenicals; Breast Neoplasms; Cell Culture Techniques; Cell Proliferation; Daunorubicin; Docetaxel; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; MCF-7 Cells; Spheroids, Cellular; Sulfides; Taxoids; Tissue Scaffolds | 2018 |
Modification of daunorubicin-GnRH-III bioconjugates with oligoethylene glycol derivatives to improve solubility and bioavailability for targeted cancer chemotherapy.
Topics: Animals; Breast Neoplasms; Daunorubicin; Drug Delivery Systems; Female; Gonadotropin-Releasing Hormone; Humans; MCF-7 Cells; Polyethylene Glycols; Rats; Solubility | 2015 |
Relation of Pre-anthracycline Serum Bilirubin Levels to Left Ventricular Ejection Fraction After Chemotherapy.
Topics: Adult; Aged; Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Agents; Bilirubin; Breast Neoplasms; Daunorubicin; Doxorubicin; Female; Hematologic Neoplasms; Humans; Idarubicin; Male; Middle Aged; Oxidative Stress; Retrospective Studies; Stroke Volume; Ventricular Dysfunction, Left | 2015 |
The efficacy of WGA modified daunorubicin anti-resistant liposomes in treatment of drug-resistant MCF-7 breast cancer.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Daunorubicin; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Liposomes; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Wheat Germ Agglutinins; Xenograft Model Antitumor Assays | 2017 |
[High risk of cardiac dysfunction after treatment of secondary acute myeloid leukemia following chemotherapy and radiotherapy for breast cancer].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Cyclophosphamide; Daunorubicin; Epirubicin; Female; Fluorouracil; Heart Diseases; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid; Middle Aged; Neoplasms, Second Primary; Remission Induction; Stroke Volume | 2010 |
Macelignan: a new modulator of P-glycoprotein in multidrug-resistant cancer cells.
Topics: Adenocarcinoma; Analysis of Variance; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; Biological Transport, Active; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Daunorubicin; Dose-Response Relationship, Drug; Drug Design; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Female; Fluorescent Dyes; Growth Inhibitors; Humans; Lignans; Phytoestrogens; Phytotherapy; Rhodamine 123; Vinblastine | 2009 |
Mees lines and Beau lines after chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cytarabine; Daunorubicin; Docetaxel; Female; Humans; Leukemia, Myeloid, Acute; Nail Diseases; Taxoids | 2010 |
Effects of stealth liposomal daunorubicin plus tamoxifen on the breast cancer and cancer stem cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Line, Tumor; Daunorubicin; Drug Delivery Systems; Drug Synergism; Female; Humans; In Situ Nick-End Labeling; Liposomes; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Particle Size; Tamoxifen; Tissue Distribution; Xenograft Model Antitumor Assays | 2010 |
Targeting therapy with mitosomal daunorubicin plus amlodipine has the potential to circumvent intrinsic resistant breast cancer.
Topics: Amlodipine; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cytochromes c; Daunorubicin; Drug Carriers; Drug Resistance, Neoplasm; Female; Humans; In Situ Nick-End Labeling; Liposomes; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Mice, Nude; Mitochondria | 2011 |
In vitro evaluation and biodistribution of HER2-targeted liposomes loaded with an (125)I-labelled DNA-intercalator.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Daunorubicin; Dose-Response Relationship, Drug; Drug Delivery Systems; Female; Humans; Injections, Intraperitoneal; Intercalating Agents; Iodine Radioisotopes; Liposomes; Mice; Mice, Inbred BALB C; Mice, Nude; Ovarian Neoplasms; Receptor, ErbB-2; Tissue Distribution | 2011 |
Anthracycline-GnRH derivative bioconjugates with different linkages: synthesis, in vitro drug release and cytostatic effect.
Topics: Amino Acid Sequence; Antibiotics, Antineoplastic; Breast Neoplasms; Cathepsin B; Cell Line, Tumor; Colonic Neoplasms; Daunorubicin; Doxorubicin; Female; Gonadotropin-Releasing Hormone; Humans; Lysosomes | 2011 |
Mitochondrial targeting liposomes incorporating daunorubicin and quinacrine for treatment of relapsed breast cancer arising from cancer stem cells.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Caspase 3; Caspase 9; Cell Line, Tumor; Cytochromes c; Daunorubicin; Female; Humans; Liposomes; Membrane Potential, Mitochondrial; Mice; Mice, SCID; Mitochondria; Neoplasm Recurrence, Local; Neoplastic Stem Cells; Quinacrine | 2012 |
Downregulation of Mcl-1 by daunorubicin pretreatment reverses resistance of breast cancer cells to TNF-related apoptosis-inducing ligand.
Topics: Antibiotics, Antineoplastic; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Daunorubicin; DNA Damage; Down-Regulation; Drug Resistance, Neoplasm; Female; Humans; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-bcl-2; RNA Interference; TNF-Related Apoptosis-Inducing Ligand | 2012 |
A platelet-mimetic paradigm for metastasis-targeted nanomedicine platforms.
Topics: Antineoplastic Agents; Biomimetic Materials; Blood Platelets; Breast Neoplasms; Daunorubicin; Drug Delivery Systems; Female; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Liposomes; MCF-7 Cells; Nanomedicine; Rhodamines | 2013 |
Reversal of multidrug resistance-associated protein-mediated daunorubicin resistance by camptothecin.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Cell Line; Cell Nucleus; Chemokines, CC; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Leukemia; Microscopy, Confocal; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2002 |
Liposomal daunorubicin overcomes drug resistance in human breast, ovarian and lung carcinoma cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma, Small Cell; Cell Death; Daunorubicin; Drug Resistance, Neoplasm; Female; Humans; Inhibitory Concentration 50; Liposomes; Lung Neoplasms; Ovarian Neoplasms; Tumor Cells, Cultured | 2002 |
High-dose consolidation chemotherapy with Idarubicin and alkylating agents following induction with gemcitabine-epirubicin-paclitaxel in metastatic breast cancer: a dose finding study.
Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Daunorubicin; Deoxycytidine; Disease Progression; Disease-Free Survival; Dose-Response Relationship, Drug; Epirubicin; Female; Humans; Idarubicin; Melphalan; Middle Aged; Neoplasm Metastasis; Paclitaxel; Remission Induction; Taxoids; Thiotepa; Time Factors; Transplantation Conditioning; Treatment Outcome | 2003 |
Isomer-dependent daunomycin release and in vitro antitumour effect of cis-aconityl-daunomycin.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Survival; Colonic Neoplasms; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Female; Humans; Indicators and Reagents; Isomerism; Kinetics; Magnetic Resonance Spectroscopy; Tumor Cells, Cultured | 2003 |
Reversal of breast cancer resistance protein-mediated drug resistance by tryprostatin A.
Topics: Acridines; Antineoplastic Agents; Breast Neoplasms; Cell Division; Daunorubicin; Drug Resistance, Multiple; Female; Humans; Indole Alkaloids; Kinetics; Mitoxantrone; Piperazines; Stomach Neoplasms; Tetrahydroisoquinolines; Tumor Cells, Cultured | 2003 |
Hypoxia-induced acidification causes mitoxantrone resistance not mediated by drug transporters in human breast cancer cells.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glycolysis; Humans; Hydrogen-Ion Concentration; Hypoxia; Immunoblotting; Inhibitory Concentration 50; Mitoxantrone | 2005 |
Prediction of doxorubicin sensitivity in breast tumors based on gene expression profiles of drug-resistant cell lines correlates with patient survival.
Topics: Algorithms; Antibiotics, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Daunorubicin; Doxorubicin; Drug Resistance, Neoplasm; Female; Forecasting; Gene Expression Profiling; Humans; Mitoxantrone; Oligonucleotide Array Sequence Analysis; Predictive Value of Tests; Prognosis; Stomach Neoplasms; Survival Analysis | 2005 |
Inhibition of P-glycoprotein by natural products in human breast cancer cells.
Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Daunorubicin; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Flavonoids; Genistein; Humans; Inhibitory Concentration 50; Quercetin; Silymarin | 2005 |
Idarubicin and idarubicinol effects on breast cancer multicellular spheroids.
Topics: Antibiotics, Antineoplastic; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Daunorubicin; Dose-Response Relationship, Drug; Female; Humans; Idarubicin; Inhibitory Concentration 50; Spheroids, Cellular; Time Factors | 2005 |
Cyclohexylpiperazine derivative PB28, a sigma2 agonist and sigma1 antagonist receptor, inhibits cell growth, modulates P-glycoprotein, and synergizes with anthracyclines in breast cancer.
Topics: Anthracyclines; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Daunorubicin; Drug Synergism; Female; Humans; Piperazines; Receptors, sigma; Sigma-1 Receptor | 2006 |
Synthesis of daunorubicin analogues containing truncated aromatic cores and unnatural monosaccharide residues.
Topics: Anthracyclines; Antibiotics, Antineoplastic; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Daunorubicin; Drug Screening Assays, Antitumor; Humans; Monosaccharides; Structure-Activity Relationship | 2007 |
Cardiac risks in multimodal breast cancer treatment.
Topics: Anthracyclines; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Breast Neoplasms; Clinical Trials as Topic; Combined Modality Therapy; Daunorubicin; Female; Follow-Up Studies; Heart; Heart Diseases; Humans; Meta-Analysis as Topic; Radiotherapy Dosage; Radiotherapy, Adjuvant; Risk; Time Factors; Trastuzumab | 2007 |
MGN-3/Biobran, modified arabinoxylan from rice bran, sensitizes human breast cancer cells to chemotherapeutic agent, daunorubicin.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Chemotherapy, Adjuvant; Daunorubicin; Dose-Response Relationship, Drug; Drug Synergism; Humans; Xylans | 2008 |
Phase II study of carminomycin in a human tumor cloning assay.
Topics: Breast Neoplasms; Carubicin; Colony-Forming Units Assay; Daunorubicin; Doxorubicin; Drug Evaluation; Female; Humans; Melanoma; Ovarian Neoplasms; Tumor Stem Cell Assay | 1984 |
Pharmacokinetics of carminomycin in man: biweekly schedule vs single dose every three weeks.
Topics: Adult; Aged; Breast Neoplasms; Carubicin; Daunorubicin; Drug Administration Schedule; Female; Humans; Kinetics; Middle Aged | 1984 |
Carminomycin. A new anthracycline analog in the treatment of advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carubicin; Cyclophosphamide; Daunorubicin; Drug Evaluation; Female; Fluorouracil; Humans; Methotrexate; Middle Aged; Myeloproliferative Disorders; Prednisone; Time Factors; Vincristine | 1984 |
[Measurements of ion concentrations with microelectrodes on vital tissue sections of human breast cancer].
Topics: Breast Neoplasms; Chlorides; Culture Techniques; Daunorubicin; Female; Humans; Membrane Potentials; Microelectrodes; Osmolar Concentration; Potassium; Sodium | 1983 |
Phase II evaluation of rubidazone (NSC-164011) in advanced carcinoma of the breast. A Southwest Oncology Group study.
Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Daunorubicin; Drug Evaluation; Female; Hematologic Diseases; Humans; Middle Aged; Risk; Time Factors | 1983 |
[Comparative evaluation of the results of mono- and polychemotherapy of disseminated forms of breast cancer using the CMFVP program and anthracycline antibiotics (carminomycin and adriamycin)].
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carubicin; Cyclophosphamide; Daunorubicin; Doxorubicin; Fluorouracil; Humans; Methotrexate; Neoplasm Metastasis; Prednisone; Vincristine | 1983 |
Plasma concentrations of carminomycin and carminomycinol in man, measured by high pressure liquid chromatography.
Topics: Breast Neoplasms; Carubicin; Chromatography, High Pressure Liquid; Daunorubicin; Humans; Sarcoma; Soft Tissue Neoplasms; Time Factors | 1982 |
Preliminary results of a phase II trial on solid tumors of detorubicin, a new anthracyclin.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Daunorubicin; Dose-Response Relationship, Drug; Drug Evaluation; Female; Head and Neck Neoplasms; Humans; Male; Melanoma; Middle Aged; Neoplasms; Uterine Neoplasms | 1980 |
Susceptibility of idarubicin, daunorubicin, and their C-13 alcohol metabolites to transport-mediated multidrug resistance.
Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Breast Neoplasms; Cell Survival; Culture Media; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Stability; HL-60 Cells; Humans; Idarubicin; Intracellular Fluid; Tumor Cells, Cultured | 1995 |
Characterization of a new monoclonal antibody F4 detecting cell surface epitope and P-glycoprotein in drug-resistant human tumor cell lines.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Neoplasm; Antibody Specificity; Antigens, Neoplasm; Antigens, Surface; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Carrier Proteins; CHO Cells; Cricetinae; Daunorubicin; Doxorubicin; Drug Resistance; Epitopes; Female; Humans; KB Cells; Membrane Glycoproteins; Neoplasm Proteins; Ovarian Neoplasms; Protein Structure, Tertiary; Tumor Cells, Cultured; Vincristine | 1993 |
Practice alert: FDA approves Zinecard.
Topics: Breast Neoplasms; Cardiomyopathies; Chelating Agents; Daunorubicin; Doxorubicin; Female; Humans; United States; United States Food and Drug Administration | 1995 |
Angiotensin converting enzyme inhibitors in bone marrow transplant recipients with depressed left ventricular function.
Topics: Adolescent; Adult; Angiotensin-Converting Enzyme Inhibitors; Antibiotics, Antineoplastic; Antineoplastic Agents; Bone Marrow Transplantation; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Daunorubicin; Doxorubicin; Echocardiography, Doppler, Color; Enalapril; Female; Gated Blood-Pool Imaging; Heart Failure; Humans; Idarubicin; Leukemia; Male; Middle Aged; Radiation Injuries; Radiotherapy; Ventricular Dysfunction, Left; Ventricular Function, Left | 1995 |
Influence of S9788, a new modulator of multidrug resistance, on the cellular accumulation and subcellular distribution of daunorubicin in P-glycoprotein-expressing MCF7 human breast adenocarcinoma cells.
Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Nucleus; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Female; Flow Cytometry; Humans; Neoplasm Proteins; Piperidines; Subcellular Fractions; Triazines; Tumor Cells, Cultured; Verapamil | 1995 |
Partial inhibition of multidrug resistance by safingol is independent of modulation of P-glycoprotein substrate activities and correlated with inhibition of protein kinase C.
Topics: Affinity Labels; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Breast Neoplasms; Cell Line; Cell Membrane; Cell Survival; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Enzyme Inhibitors; Female; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Myristoylated Alanine-Rich C Kinase Substrate; Phorbol 12,13-Dibutyrate; Protein Kinase C; Proteins; Rats; Recombinant Proteins; Sphingosine; Substrate Specificity; Tumor Cells, Cultured; Verapamil; Vinblastine | 1995 |
[Effect of the modality of exposure on the action of S9788 on the modulation of multidrug resistance of human tumor cell lines].
Topics: Adenocarcinoma; Antineoplastic Agents; Breast Neoplasms; Cyclosporine; Daunorubicin; Drug Resistance, Multiple; Humans; Leukemia; Piperidines; Triazines; Tumor Cells, Cultured; Verapamil | 1994 |
Expression of a 95 kDa membrane protein is associated with low daunorubicin accumulation in leukaemic blast cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Breast Neoplasms; Daunorubicin; Drug Resistance, Multiple; Humans; Leukemia, Myeloid, Acute; Membrane Proteins; Molecular Weight; Neoplasm Proteins; Tumor Cells, Cultured | 1995 |
Testing of a chemosensitivity screening method on sensitive and resistant breast tumoral epithelial cell lines.
Topics: Breast Neoplasms; Cell Cycle; Chromatin; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Screening Assays, Antitumor; Female; Humans; Image Processing, Computer-Assisted; Tumor Cells, Cultured | 1994 |
[Six cases of therapy related leukemia; case reports and review of the literature].
Topics: Aclarubicin; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Cyclophosphamide; Daunorubicin; Female; Humans; Leukemia, Myelomonocytic, Acute; Leukemia, Promyelocytic, Acute; Lung Neoplasms; Lymphoma; Male; Middle Aged; Neoplasms, Second Primary; Survival Rate | 1993 |
Heterogeneity of anthracycline retention and response to efflux blockers in human tumors.
Topics: Anthracyclines; Ascites; Breast Neoplasms; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Female; Flow Cytometry; Genetic Heterogeneity; Humans; Verapamil | 1995 |
Quantitation of the nucleophosmin/B23-translocation using imaging analysis.
Topics: Aclarubicin; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Nucleolus; Dactinomycin; Daunorubicin; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Humans; Image Processing, Computer-Assisted; Leukemia, Monocytic, Acute; Nuclear Proteins; Nucleophosmin; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured | 1996 |
DaunoXome shows promise as breast cancer treatment.
Topics: Antibiotics, Antineoplastic; Breast Neoplasms; Daunorubicin; Drug Administration Schedule; Female; Humans; Treatment Outcome | 1996 |
Comparative in vitro evaluation of dithiane analogs of tiapamil, Ro 11-2933, Ro 44-5911 and Ro 44-5912 as multidrug resistance modulators.
Topics: Adenocarcinoma; Breast Neoplasms; Calcium Channel Blockers; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Flow Cytometry; Humans; Leukemia, Experimental; Propylamines; Tumor Cells, Cultured; Verapamil | 1996 |
[Echocardiographic evaluation of cardiotoxicity induced by anthracycline therapy].
Topics: Aclarubicin; Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Breast Neoplasms; Daunorubicin; Doxorubicin; Echocardiography; Epirubicin; Female; Heart; Hematologic Diseases; Humans; Male; Middle Aged; Mitoxantrone; Radionuclide Imaging; Stroke Volume | 1997 |
Reduced drug accumulation and multidrug resistance in human breast cancer cells without associated P-glycoprotein or MRP overexpression.
Topics: Antibiotics, Antineoplastic; Antigens, Neoplasm; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Division; Cloning, Molecular; Daunorubicin; DNA Topoisomerases, Type II; DNA-Binding Proteins; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Fluorescent Dyes; Humans; Isoenzymes; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Phenotype; Polymerase Chain Reaction; Rhodamines; Sodium Channels; Subcellular Fractions; Tumor Cells, Cultured | 1997 |
Autologous bone marrow purging by in situ IL-2 activation of endogenous killer cells.
Topics: Bone Marrow Purging; Bone Marrow Transplantation; Breast Neoplasms; Colony-Forming Units Assay; Cytarabine; Cytotoxicity, Immunologic; Daunorubicin; Drug Resistance, Neoplasm; Etoposide; Female; Hematopoietic Stem Cells; HL-60 Cells; Humans; Interleukin-2; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Leukemia; Lung Neoplasms; Lymphocyte Activation; Tissue Donors; Transplantation, Autologous; Transplantation, Homologous; Tumor Cells, Cultured | 1997 |
Antineoplastic drugs that interfere with iron metabolism in cancer cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Cisplatin; Clinical Trials as Topic; Daunorubicin; Deferoxamine; Female; Gallium; Humans; Indium; Iron; Rats; Transferrin; Tumor Cells, Cultured | 1997 |
Role of the vacuolar H+-ATPase in daunorubicin distribution in etoposide-resistant MCF7 cells overexpressing the multidrug-resistance associated protein.
Topics: 4-Chloro-7-nitrobenzofurazan; Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Cell Nucleus; Cholesterol; Cytoplasm; Daunorubicin; Drug Resistance, Multiple; Etoposide; Female; Humans; Norsteroids; Proton-Translocating ATPases; Tumor Cells, Cultured; Vacuolar Proton-Translocating ATPases; Verapamil | 1998 |
Bryostatin 1 affects P-glycoprotein phosphorylation but not function in multidrug-resistant human breast cancer cells.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Bryostatins; Daunorubicin; Down-Regulation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Activation; Female; Humans; Isoenzymes; Lactones; Macrolides; Neoplasm Proteins; Phosphorylation; Protein Kinase C; Rhodamines; Tumor Cells, Cultured; Vinblastine | 1995 |
A multidrug resistance transporter from human MCF-7 breast cancer cells.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Cell Survival; Cloning, Molecular; Daunorubicin; DNA Primers; Drug Resistance, Multiple; Female; Gene Library; Humans; Molecular Sequence Data; Neoplasm Proteins; Phylogeny; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Software; Transcription, Genetic; Transfection; Tumor Cells, Cultured | 1998 |
Lack of competition of substrates for P-glycoprotein in MCF-7 breast cancer cells overexpressing MDR1.
Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Daunorubicin; Doxorubicin; Drug Resistance, Multiple; Energy Metabolism; Female; Gene Expression; Humans; Nucleotides; Tumor Cells, Cultured | 1999 |
Crystal structure of epidoxorubicin-formaldehyde virtual crosslink of DNA and evidence for its formation in human breast-cancer cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Cross-Linking Reagents; Crystallography, X-Ray; Daunorubicin; DNA Adducts; DNA, Neoplasm; Epirubicin; Humans; Intercalating Agents; Nucleic Acid Conformation; Oligonucleotides; Tissue Distribution; Tumor Cells, Cultured | 1999 |
Toremifene increases the expression of intercellular adhesion molecule-1 (ICAM-1) on MCF-7 breast cancer cells and Jurkat cells.
Topics: Antineoplastic Agents, Hormonal; Apoptosis; B7-1 Antigen; Breast Neoplasms; CD40 Antigens; Daunorubicin; fas Receptor; Female; HLA-DR Antigens; Humans; Intercellular Adhesion Molecule-1; Interferon-gamma; Jurkat Cells; Recombinant Proteins; Selective Estrogen Receptor Modulators; Toremifene; Tumor Cells, Cultured | 2000 |
Regulation of cellular glutathione modulates nuclear accumulation of daunorubicin in human MCF7 cells overexpressing multidrug resistance associated protein.
Topics: Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Breast Neoplasms; Buthionine Sulfoximine; Cell Nucleus; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Female; Flow Cytometry; Glutathione; Glutathione Synthase; Humans; Microscopy, Confocal; Multidrug Resistance-Associated Proteins; Reverse Transcriptase Polymerase Chain Reaction; Spectrometry, Fluorescence; Tumor Cells, Cultured | 2000 |
Modulation of daunorubicin toxicity by liposomal encapsulation and use of specific inhibitors in vitro.
Topics: Antibiotics, Antineoplastic; Breast Neoplasms; Daunorubicin; Drug Carriers; Drug Compounding; Drug Resistance, Neoplasm; Humans; Liposomes; Rutin; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured | 2000 |
Mass spectrometric measurement of formaldehyde generated in breast cancer cells upon treatment with anthracycline antitumor drugs.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Cross-Linking Reagents; Daunorubicin; Doxorubicin; Female; Formaldehyde; Humans; Mass Spectrometry; Tumor Cells, Cultured | 2000 |
Modulation of daunorubicin cellular resistance by combination of P-glycoprotein blockers acting on drug efflux and intracellular drug sequestration in Golgi vesicles.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; beta 2-Microglobulin; Biological Transport; Breast Neoplasms; Cyclosporins; Daunorubicin; DNA Primers; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flow Cytometry; Gene Expression Regulation, Neoplastic; Golgi Apparatus; Humans; Microscopy, Fluorescence; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Phenotype; Piperidines; Triazines; Tumor Cells, Cultured; Vault Ribonucleoprotein Particles | 2000 |
Reversal of multidrug resistance-associated protein-mediated drug resistance in cultured human neuroblastoma cells by the quinolone antibiotic difloxacin.
Topics: Adenocarcinoma; Anti-Infective Agents; Antimony Potassium Tartrate; ATP-Binding Cassette Transporters; Breast Neoplasms; Ciprofloxacin; Cisplatin; Daunorubicin; Doxorubicin; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluoroquinolones; Gene Amplification; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Neuroblastoma; Polymerase Chain Reaction; Substrate Specificity; Tumor Cells, Cultured; Vincristine | 2001 |
Homocamptothecin-daunorubicin association overcomes multidrug-resistance in breast cancer MCF7 cells.
Topics: Adenocarcinoma; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Camptothecin; Carcinoma; Colonic Neoplasms; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Leukemia, Myeloid; Microbial Sensitivity Tests; Multidrug Resistance-Associated Proteins; Polymerase Chain Reaction; RNA, Neoplasm; Treatment Outcome; Tumor Cells, Cultured | 2002 |
Sensitivity tests of tumors to cytostatic agents. II. Investigation on human tumors.
Topics: Antineoplastic Agents; Autoradiography; Breast Neoplasms; Cell Count; Cell Division; Culture Techniques; Dactinomycin; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Lung Neoplasms; Neoplasms; Nucleic Acids; Ovarian Neoplasms; Procarbazine; Uridine | 1975 |
Cytostatic efficacy of DNA-complexes of adriamycin, daunomycin and actinomycin D. I. Comparative studies in Novikoff hepatoma, human mammary carcinoma cells and human leukemic leukocytes.
Topics: Acute Disease; Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Hepatocellular; Dactinomycin; Daunorubicin; DNA, Neoplasm; Doxorubicin; Female; Humans; Leukemia; Liver Neoplasms; Pinocytosis; Rats; RNA, Neoplasm | 1977 |
[A case of acute promyelocytic leukemia with skin nodules and mammary tumors during hematologic remission (author's transl)].
Topics: Adult; Breast Neoplasms; Daunorubicin; Female; Humans; Leukemia, Myeloid, Acute; Remission, Spontaneous; Skin Neoplasms | 1978 |
Clinical studies with rubidazone.
Topics: Acute Disease; Adult; Breast Neoplasms; Daunorubicin; Drug Evaluation; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Monocytic, Acute; Male | 1979 |
Evaluation of a method for detection of cells with reduced drug retention in solid tumours.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Breast Neoplasms; Cell Survival; Chromatography, High Pressure Liquid; Culture Media; Cyclosporine; Daunorubicin; Drug Resistance; Female; Flow Cytometry; Friend murine leukemia virus; Humans; Hydrogen-Ion Concentration; Leukemia, Erythroblastic, Acute; Membrane Glycoproteins; Mice; Neoplasm Proteins; Neoplasms; Nephelometry and Turbidimetry; Reference Standards; Reproducibility of Results; Treatment Outcome; Tumor Cells, Cultured; Verapamil | 1992 |
Subrenal capsule assay of human tumor chemosensitivity.
Topics: Aclarubicin; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Colonic Neoplasms; Cyclophosphamide; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Evaluation Studies as Topic; Fluorouracil; Humans; Mice; Neoplasm Transplantation; Subrenal Capsule Assay | 1991 |
Nuclear texture parameters as discriminant factors in cell cycle and drug sensitivity studies.
Topics: Antibiotics, Antineoplastic; Breast Neoplasms; Cell Cycle; Cell Line; Cell Nucleus; Daunorubicin; DNA; Drug Hypersensitivity; Drug Resistance; Epithelium; Female; Humans; Image Processing, Computer-Assisted; Mathematics; Models, Biological; Time Factors; Tumor Cells, Cultured | 1991 |
Antitumor activity and pharmacokinetics of a morpholino-anthracycline derivative (KRN8602) against human breast carcinoma xenografts serially transplanted into nude mice.
Topics: Animals; Antibiotics, Antineoplastic; Breast Neoplasms; Carubicin; Daunorubicin; Drug Administration Schedule; Drug Screening Assays, Antitumor; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Specific Pathogen-Free Organisms | 1990 |
Role of oxygen free radical formation in the mechanism of menogaril resistance in multidrug resistant tumor cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Survival; Chemical Phenomena; Chemistry; Daunorubicin; DNA; Doxorubicin; Drug Resistance; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Menogaril; Nogalamycin; Oxygen; Tumor Cells, Cultured | 1990 |
Interaction of anthracyclinic antibiotics with cytoskeletal components of cultured carcinoma cells (CG5).
Topics: Actins; Antibiotics, Antineoplastic; Breast Neoplasms; Cell Transformation, Neoplastic; Cytochalasin B; Cytoskeleton; Daunorubicin; Demecolcine; Doxorubicin; Humans; Microscopy, Electron; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Tubulin; Tumor Cells, Cultured | 1990 |
[Phase I clinical study of MX2 (KRN 8602)].
Topics: Adult; Antibiotics, Antineoplastic; Breast Neoplasms; Carubicin; Daunorubicin; Drug Evaluation; Female; Humans; Injections, Intravenous; Leukopenia; Male; Middle Aged; Nausea; Stomach Neoplasms; Vomiting | 1990 |
Preliminary correlations of clinical outcome with in vitro chemosensitivity of second passage human breast cancer cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Carcinoma; Cell Survival; Cisplatin; Daunorubicin; Doxorubicin; Epirubicin; Humans; In Vitro Techniques; Prognosis; Tumor Cells, Cultured; Vinblastine | 1990 |
Resistance of paraquat and adriamycin in human breast tumor cells: role of free radical formation.
Topics: Breast Neoplasms; Chromium; Daunorubicin; DNA; Doxorubicin; Drug Resistance; Female; Humans; Hydroxides; Hydroxyl Radical; Paraquat; Tumor Cells, Cultured | 1989 |
[Comparative study of the cytotoxic effects of anthracycline antibiotics on heterotransplants of human breast cancer cultivated in diffusion chambers in vivo].
Topics: Animals; Breast Neoplasms; Carubicin; Cell Division; Daunorubicin; Diffusion Chambers, Culture; Doxorubicin; Female; Humans; In Vitro Techniques; Mice; Peritoneal Cavity; Transplantation, Heterologous | 1989 |
Pharmacokinetics of oral idarubicin in breast cancer patients with reference to antitumor activity and side effects.
Topics: Administration, Oral; Aged; Biological Availability; Breast Neoplasms; Daunorubicin; Half-Life; Humans; Idarubicin; Male; Middle Aged | 1989 |
Cytotoxic activity of daunorubicin or vindesin conjugated to a monoclonal antibody on cultured MCF-7 breast carcinoma cells.
Topics: Antibodies, Monoclonal; Antigen-Antibody Reactions; Breast Neoplasms; Daunorubicin; Drug Screening Assays, Antitumor; Humans; Hydrolysis; Membrane Glycoproteins; Mucin-1; Tumor Cells, Cultured; Vindesine | 1989 |
In vitro activity of menogaril and N-demethylmenogaril in a human tumor cloning assay.
Topics: Breast Neoplasms; Cell Survival; Daunorubicin; Dose-Response Relationship, Drug; Female; Humans; Menogaril; Neoplastic Stem Cells; Nogalamycin; Ovarian Neoplasms; Tumor Stem Cell Assay | 1986 |
Phase II study of intravenous menogaril in patients with advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Daunorubicin; Drug Evaluation; Female; Humans; Infusions, Intravenous; Leukopenia; Menogaril; Middle Aged; Nogalamycin; Skin; Thrombocytopenia | 1988 |
Phase II evaluation of menogaril in women with metastatic breast cancer after failure of first-line chemotherapy.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Daunorubicin; Drug Administration Schedule; Drug Evaluation; Female; Humans; Menogaril; Neoplasm Metastasis; Nogalamycin | 1988 |
Intravenous administration of cyclophosphamide, methotrexate and 5-fluorouracil in metastatic breast cancer. A pilot study.
Topics: Administration, Oral; Bone Neoplasms; Breast Neoplasms; Daunorubicin; Drug Evaluation; Female; Humans; Idarubicin; Remission Induction; Soft Tissue Neoplasms | 1988 |
4-Demethoxydaunorubicin administered orally in advanced breast cancer. A phase II study.
Topics: Acute Kidney Injury; Administration, Oral; Adult; Aged; Bone Marrow Diseases; Bone Neoplasms; Breast Neoplasms; Daunorubicin; Female; Humans; Idarubicin; Middle Aged; Nausea; Soft Tissue Neoplasms; Stomach Ulcer; Vomiting | 1988 |
A phase II study of oral idarubicin (4-demethoxydaunorubicin) in advanced breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Daunorubicin; Drug Evaluation; Female; Humans; Idarubicin; Middle Aged | 1988 |
Potentiation of adriamycin accumulation and effectiveness in adriamycin-resistant cells by aclacinomycin A.
Topics: Aclarubicin; Animals; Antibiotics, Antineoplastic; Breast Neoplasms; Daunorubicin; Doxorubicin; Drug Resistance; Drug Synergism; Epithelial Cells; Humans; Kidney; Leukemia, Experimental; Naphthacenes; Tumor Cells, Cultured | 1988 |
Combination chemotherapy with 5-fluorouracil, oral Idarubicin, and cyclophosphamide (FIC) in metastatic breast cancer--an open phase II study.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cyclophosphamide; Daunorubicin; Drug Evaluation; Fluorouracil; Humans; Idarubicin; Methotrexate; Prednisone; Vincristine | 1988 |
Mitoxantrone.
Topics: Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cytarabine; Daunorubicin; DNA; Drug Administration Schedule; Humans; Leukemia; Mitoxantrone | 1988 |
Low dose oral administration of 4-demethoxydaunorubicin (idarubicin) in advanced cancer patients. A pharmacokinetic study.
Topics: Administration, Oral; Antibiotics, Antineoplastic; Breast Neoplasms; Daunorubicin; Heart; Humans; Idarubicin; Kinetics; Melanoma | 1986 |
Phase II trial with oral idarubicin in advanced breast cancer.
Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Daunorubicin; Drug Evaluation; Female; Humans; Idarubicin; Leukopenia; Middle Aged; Thrombocytopenia | 1986 |
[An unusual way of manifesting acute granulocytic leukemia: granulocytic sarcoma of the breast. Apropos of a case with trisomy 22].
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chromosomes, Human, 21-22 and Y; Cytarabine; Daunorubicin; Female; Granulocytes; Humans; Karyotyping; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Neoplasms, Multiple Primary; Trisomy | 1986 |
Idarubicin in advanced breast cancer: a phase II study.
Topics: Aged; Breast Neoplasms; Daunorubicin; Drug Evaluation; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Idarubicin; Middle Aged; Neoplasm Metastasis | 1986 |
New anthracycline analogs in advanced breast cancer.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Breast Neoplasms; Daunorubicin; Doxorubicin; Drug Evaluation; Epirubicin; Female; Humans; Idarubicin; Middle Aged; Naphthacenes | 1986 |
Phase II study of idarubicin given orally in the treatment of anthracycline-naive advanced breast cancer patients.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Breast Neoplasms; Daunorubicin; Drug Evaluation; Female; Humans; Idarubicin; Middle Aged | 1987 |
Clinical pharmacology of oral and intravenous 4-demethoxydaunorubicin.
Topics: Administration, Oral; Biological Availability; Breast Neoplasms; Daunorubicin; Drug Administration Schedule; Female; Humans; Idarubicin; Injections, Intravenous; Metabolic Clearance Rate | 1987 |
Phase II study of oral 4-demethoxydaunorubicin in previously treated (except anthracyclines) metastatic breast cancer patients.
Topics: Administration, Oral; Adult; Aged; Antibiotics, Antineoplastic; Breast Neoplasms; Daunorubicin; Drug Administration Schedule; Drug Evaluation; Female; Humans; Idarubicin; Lymphatic Metastasis; Middle Aged; Remission Induction; Soft Tissue Neoplasms | 1987 |
A phase II study of oral weekly 4-demethoxydaunorubicin in advanced breast cancer.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Breast Neoplasms; Daunorubicin; Doxorubicin; Drug Evaluation; Female; Humans; Idarubicin; Middle Aged | 1987 |
Phase II evaluation of orally administered idarubicin in patients with advanced breast cancer.
Topics: Administration, Oral; Adult; Aged; Breast Neoplasms; Carcinoma; Daunorubicin; Drug Evaluation; Female; Humans; Idarubicin; Middle Aged | 1987 |
Phase-II trial of oral idarubicin (4-demethoxydaunorubicin) in advanced breast cancer.
Topics: Antibiotics, Antineoplastic; Breast Neoplasms; Daunorubicin; Drug Evaluation; Female; Humans; Idarubicin; Leukopenia; Neoplasm Metastasis | 1986 |
Patterns of anthracycline retention modulation in human tumor cells.
Topics: Bone Marrow; Breast Neoplasms; Daunorubicin; Doxorubicin; Female; Humans; Leukemia; Lung Neoplasms; Microscopy, Fluorescence; Neoplasms | 1987 |
Activity of 4-demethoxydaunorubicin by the oral route in advanced breast cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Breast Neoplasms; Daunorubicin; Female; Humans; Idarubicin; Male; Middle Aged | 1985 |
1,-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (methyl CCNU) and adriamycin combination therapy.
Topics: Adult; Aged; Alopecia; Breast Neoplasms; Cyclohexanes; Daunorubicin; Digestive System; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Heart; Humans; Kidney Neoplasms; Leukopenia; Male; Middle Aged; Neoplasms; Nitrosourea Compounds; Ovarian Neoplasms; Parotid Neoplasms; Stomatitis; Thrombocytopenia; Vision Disorders | 1974 |
Acute leukemia presenting as a breast mass.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Biopsy, Needle; Breast Neoplasms; Child; Cytarabine; Daunorubicin; Diagnosis, Differential; Female; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Menarche; Mercaptopurine; Methotrexate; Prednisolone; Sulfates; Vincristine | 1973 |
Cecal necrosis and perforation with systemic chemotherapy.
Topics: Adult; Asparaginase; Breast Neoplasms; Cecal Diseases; Child; Cytarabine; Daunorubicin; Female; Fluorouracil; Humans; Intestinal Perforation; Leukemia; Male; Mercaptopurine; Methotrexate; Middle Aged; Necrosis; Prednisone; Thioguanine; Vincristine | 1973 |
Evolution of a practical policy for chemotherapy of carcinoma of the breast.
Topics: Blood Cell Count; Breast Neoplasms; Cyclophosphamide; Daunorubicin; Doxorubicin; Drug Therapy, Combination; Female; Fluorouracil; Humans; Injections, Intravenous; Methotrexate; Time Factors; Vinblastine; Vincristine | 1973 |