darutigenol and Breast-Neoplasms

darutigenol has been researched along with Breast-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for darutigenol and Breast-Neoplasms

ArticleYear
Isolation and characterization of diterpene glycosides from Siegesbeckia pubescens.
    Bioorganic & medicinal chemistry letters, 2017, 04-15, Volume: 27, Issue:8

    Five new diterpenoid glycosides, siegesides A-E (1-5), along with the known compound darutoside (6) were isolated and characterized from the ethanol extract of Siegesbeckia pubescens. The structural elucidation of the isolates was accomplished by extensive HRESIMS and NMR analysis. Compounds 1 and 2 are epimers of 6. All isolates were evaluated for their inhibition on the migration of MB-MDA-231 breast cancer cells induced by the chemokine epithelial growth factor, and compound 2 showed superior inhibitory activities in comparison with the positive control drug with IC

    Topics: Antineoplastic Agents, Phytogenic; Asteraceae; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Diterpenes; Female; Glycosides; Humans; Models, Molecular; Plant Extracts

2017