dapsone has been researched along with Stroke in 2 studies
Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dapsone appears as a useful and safe drug for the treatment of stroke patients." | 9.12 | Neuroprotective effect of dapsone in patients with acute ischemic stroke: a pilot study. ( Calzada, P; Góngora-Rivera, F; Nader-Kawachi, J; Ríos, C; Santos-Zambrano, J, 2007) |
| " We have shown that dapsone acts as an antioxidant, antiinflammatory and antiapoptotic agent after brain Ischemia reperfusion (I/R) in rats; however, its therapeutic efficacy, measured by imaging has not been characterized." | 7.83 | Dapsone improves functional deficit and diminishes brain damage evaluated by 3-Tesla magnetic resonance image after transient cerebral ischemia and reperfusion in rats. ( Diaz-Ruiz, A; Heras-Romero, Y; Mendez-Armenta, M; Mondragón-Lozano, R; Nava-Ruiz, C; Ortiz-Plata, A; Osorio-Rico, L; Ríos, C; Roldan-Valadez, E, 2016) |
| "Dapsone appears as a useful and safe drug for the treatment of stroke patients." | 5.12 | Neuroprotective effect of dapsone in patients with acute ischemic stroke: a pilot study. ( Calzada, P; Góngora-Rivera, F; Nader-Kawachi, J; Ríos, C; Santos-Zambrano, J, 2007) |
| " We have shown that dapsone acts as an antioxidant, antiinflammatory and antiapoptotic agent after brain Ischemia reperfusion (I/R) in rats; however, its therapeutic efficacy, measured by imaging has not been characterized." | 3.83 | Dapsone improves functional deficit and diminishes brain damage evaluated by 3-Tesla magnetic resonance image after transient cerebral ischemia and reperfusion in rats. ( Diaz-Ruiz, A; Heras-Romero, Y; Mendez-Armenta, M; Mondragón-Lozano, R; Nava-Ruiz, C; Ortiz-Plata, A; Osorio-Rico, L; Ríos, C; Roldan-Valadez, E, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Diaz-Ruiz, A | 1 |
| Roldan-Valadez, E | 1 |
| Ortiz-Plata, A | 1 |
| Mondragón-Lozano, R | 1 |
| Heras-Romero, Y | 1 |
| Mendez-Armenta, M | 1 |
| Osorio-Rico, L | 1 |
| Nava-Ruiz, C | 1 |
| Ríos, C | 2 |
| Nader-Kawachi, J | 1 |
| Góngora-Rivera, F | 1 |
| Santos-Zambrano, J | 1 |
| Calzada, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Trial Randomized, Placebo-controlled, Using Dapsone as a Neuroprotector During Acute Ischemia Stroke[NCT01144650] | Phase 2/Phase 3 | 300 participants (Anticipated) | Interventional | 2009-07-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for dapsone and Stroke
| Article | Year |
|---|---|
Neuroprotective effect of dapsone in patients with acute ischemic stroke: a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Dapsone; Dose-Response Relationship, Drug; Double-Blind Method; Fema | 2007 |
1 other study available for dapsone and Stroke
| Article | Year |
|---|---|
Dapsone improves functional deficit and diminishes brain damage evaluated by 3-Tesla magnetic resonance image after transient cerebral ischemia and reperfusion in rats.
Topics: Animals; Brain; Brain Ischemia; Dapsone; Magnetic Resonance Imaging; Male; Neuroprotective Agents; N | 2016 |