Page last updated: 2024-10-25

dapsone and Stroke

dapsone has been researched along with Stroke in 2 studies

Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)

Research Excerpts

ExcerptRelevanceReference
"Dapsone appears as a useful and safe drug for the treatment of stroke patients."9.12Neuroprotective effect of dapsone in patients with acute ischemic stroke: a pilot study. ( Calzada, P; Góngora-Rivera, F; Nader-Kawachi, J; Ríos, C; Santos-Zambrano, J, 2007)
" We have shown that dapsone acts as an antioxidant, antiinflammatory and antiapoptotic agent after brain Ischemia reperfusion (I/R) in rats; however, its therapeutic efficacy, measured by imaging has not been characterized."7.83Dapsone improves functional deficit and diminishes brain damage evaluated by 3-Tesla magnetic resonance image after transient cerebral ischemia and reperfusion in rats. ( Diaz-Ruiz, A; Heras-Romero, Y; Mendez-Armenta, M; Mondragón-Lozano, R; Nava-Ruiz, C; Ortiz-Plata, A; Osorio-Rico, L; Ríos, C; Roldan-Valadez, E, 2016)
"Dapsone appears as a useful and safe drug for the treatment of stroke patients."5.12Neuroprotective effect of dapsone in patients with acute ischemic stroke: a pilot study. ( Calzada, P; Góngora-Rivera, F; Nader-Kawachi, J; Ríos, C; Santos-Zambrano, J, 2007)
" We have shown that dapsone acts as an antioxidant, antiinflammatory and antiapoptotic agent after brain Ischemia reperfusion (I/R) in rats; however, its therapeutic efficacy, measured by imaging has not been characterized."3.83Dapsone improves functional deficit and diminishes brain damage evaluated by 3-Tesla magnetic resonance image after transient cerebral ischemia and reperfusion in rats. ( Diaz-Ruiz, A; Heras-Romero, Y; Mendez-Armenta, M; Mondragón-Lozano, R; Nava-Ruiz, C; Ortiz-Plata, A; Osorio-Rico, L; Ríos, C; Roldan-Valadez, E, 2016)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Diaz-Ruiz, A1
Roldan-Valadez, E1
Ortiz-Plata, A1
Mondragón-Lozano, R1
Heras-Romero, Y1
Mendez-Armenta, M1
Osorio-Rico, L1
Nava-Ruiz, C1
Ríos, C2
Nader-Kawachi, J1
Góngora-Rivera, F1
Santos-Zambrano, J1
Calzada, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Clinical Trial Randomized, Placebo-controlled, Using Dapsone as a Neuroprotector During Acute Ischemia Stroke[NCT01144650]Phase 2/Phase 3300 participants (Anticipated)Interventional2009-07-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for dapsone and Stroke

ArticleYear
Neuroprotective effect of dapsone in patients with acute ischemic stroke: a pilot study.
    Neurological research, 2007, Volume: 29, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Dapsone; Dose-Response Relationship, Drug; Double-Blind Method; Fema

2007

Other Studies

1 other study available for dapsone and Stroke

ArticleYear
Dapsone improves functional deficit and diminishes brain damage evaluated by 3-Tesla magnetic resonance image after transient cerebral ischemia and reperfusion in rats.
    Brain research, 2016, 09-01, Volume: 1646

    Topics: Animals; Brain; Brain Ischemia; Dapsone; Magnetic Resonance Imaging; Male; Neuroprotective Agents; N

2016