Page last updated: 2024-10-25

dapsone and Scleritis

dapsone has been researched along with Scleritis in 5 studies

Scleritis: Refers to any inflammation of the sclera including episcleritis, a benign condition affecting only the episclera, which is generally short-lived and easily treated. Classic scleritis, on the other hand, affects deeper tissue and is characterized by higher rates of visual acuity loss and even mortality, particularly in necrotizing form. Its characteristic symptom is severe and general head pain. Scleritis has also been associated with systemic collagen disease. Etiology is unknown but is thought to involve a local immune response. Treatment is difficult and includes administration of anti-inflammatory and immunosuppressive agents such as corticosteroids. Inflammation of the sclera may also be secondary to inflammation of adjacent tissues, such as the conjunctiva.

Research Excerpts

ExcerptRelevanceReference
"Pyoderma gangrenosum is a rare autoimmune disorder that can affect the eye."5.34Sclerokeratitis and facial skin lesions: a case report of pyoderma gangrenosum and its response to dapsone therapy. ( Baltatzis, S; Foster, CS; Teasley, LA, 2007)
"Pyoderma gangrenosum is a rare autoimmune disorder that can affect the eye."1.34Sclerokeratitis and facial skin lesions: a case report of pyoderma gangrenosum and its response to dapsone therapy. ( Baltatzis, S; Foster, CS; Teasley, LA, 2007)
"Ocular manifestations are uncommon in Sweet's syndrome but it is important to diagnose and treat them."1.34Nodular scleritis and Sweet's syndrome. ( Loh, RS; Su, DH; Wong, MH, 2007)
"Dapsone, which has been reported to be effective in the treatment of relapsing polychondritis, did not control the destructive scleral inflammation in six (75%) of eight patients; two (50%) of four patients with diffuse anterior scleritis were controlled with this drug."1.28Scleritis in relapsing polychondritis. Response to therapy. ( Foster, CS; Hoang-Xaun, T; Rice, BA, 1990)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's4 (80.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Inamadar, AC1
Anitha, B1
Mitamura, Y1
Fujiwara, O1
Miyanishi, K1
Sato, H1
Saga, K1
Ohtsuka, K1
Teasley, LA1
Foster, CS2
Baltatzis, S1
Wong, MH1
Su, DH1
Loh, RS1
Hoang-Xaun, T1
Rice, BA1

Other Studies

5 other studies available for dapsone and Scleritis

ArticleYear
HIV-seropositive patient with Sweet's syndrome and nodular scleritis, showing dramatic response after adding dapsone to systemic corticosteroid therapy.
    International journal of dermatology, 2008, Volume: 47, Issue:8

    Topics: Administration, Oral; Adult; Dapsone; Dose-Response Relationship, Drug; Drug Administration Schedule

2008
Nodular scleritis and panuveitis with erythema elevatum diutinum.
    American journal of ophthalmology, 2004, Volume: 137, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Dapsone; Drug Therapy, Combination; Erythema; Female

2004
Sclerokeratitis and facial skin lesions: a case report of pyoderma gangrenosum and its response to dapsone therapy.
    Cornea, 2007, Volume: 26, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Biopsy; Dapsone; Face; Female; Follow-Up Studies; Hu

2007
Nodular scleritis and Sweet's syndrome.
    Clinical & experimental ophthalmology, 2007, Volume: 35, Issue:9

    Topics: Administration, Oral; Adult; Colchicine; Dapsone; Dexamethasone; Drug Therapy, Combination; Female;

2007
Scleritis in relapsing polychondritis. Response to therapy.
    Ophthalmology, 1990, Volume: 97, Issue:7

    Topics: Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Biopsy;

1990