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dapsone and Reperfusion Injury

dapsone has been researched along with Reperfusion Injury in 5 studies

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
" We have shown that dapsone acts as an antioxidant, antiinflammatory and antiapoptotic agent after brain Ischemia reperfusion (I/R) in rats; however, its therapeutic efficacy, measured by imaging has not been characterized."7.83Dapsone improves functional deficit and diminishes brain damage evaluated by 3-Tesla magnetic resonance image after transient cerebral ischemia and reperfusion in rats. ( Diaz-Ruiz, A; Heras-Romero, Y; Mendez-Armenta, M; Mondragón-Lozano, R; Nava-Ruiz, C; Ortiz-Plata, A; Osorio-Rico, L; Ríos, C; Roldan-Valadez, E, 2016)
"To investigate this, we created a hemorrhagic shock model rat, followed by resuscitation with RBC and CO-RBC."5.40Carbon monoxide-bound red blood cell resuscitation ameliorates hepatic injury induced by massive hemorrhage and red blood cell resuscitation via hepatic cytochrome P450 protection in hemorrhagic shock rats. ( Ishima, Y; Maruyama, T; Ogaki, S; Otagiri, M; Taguchi, K; Watanabe, H, 2014)
" Rats were dosed either with dapsone (12."5.35Antioxidant, antiinflammatory and antiapoptotic effects of dapsone in a model of brain ischemia/reperfusion in rats. ( Diaz-Ruiz, A; Montes, S; Nava-Ruiz, C; Orozco-Suarez, S; Ortiz-Plata, A; Pérez-Neri, I; Perez-Severiano, F; Ríos, C; Salgado-Ceballos, H; Zavala, C, 2008)
" We have shown that dapsone acts as an antioxidant, antiinflammatory and antiapoptotic agent after brain Ischemia reperfusion (I/R) in rats; however, its therapeutic efficacy, measured by imaging has not been characterized."3.83Dapsone improves functional deficit and diminishes brain damage evaluated by 3-Tesla magnetic resonance image after transient cerebral ischemia and reperfusion in rats. ( Diaz-Ruiz, A; Heras-Romero, Y; Mendez-Armenta, M; Mondragón-Lozano, R; Nava-Ruiz, C; Ortiz-Plata, A; Osorio-Rico, L; Ríos, C; Roldan-Valadez, E, 2016)
"Male adult Wistar rats were subjected to middle cerebral artery occlusion (MCAO) for 90 min followed by 24 h of ischemic reperfusion (I/R)."1.56Dapsone prolong delayed excitotoxic neuronal cell death by interacting with proapoptotic/survival signaling proteins. ( Gakare, S; Kumar, R; Mahale, A; Prakash, A; Sarode, LP; Ugale, RR, 2020)
"To investigate this, we created a hemorrhagic shock model rat, followed by resuscitation with RBC and CO-RBC."1.40Carbon monoxide-bound red blood cell resuscitation ameliorates hepatic injury induced by massive hemorrhage and red blood cell resuscitation via hepatic cytochrome P450 protection in hemorrhagic shock rats. ( Ishima, Y; Maruyama, T; Ogaki, S; Otagiri, M; Taguchi, K; Watanabe, H, 2014)
" Rats were dosed either with dapsone (12."1.35Antioxidant, antiinflammatory and antiapoptotic effects of dapsone in a model of brain ischemia/reperfusion in rats. ( Diaz-Ruiz, A; Montes, S; Nava-Ruiz, C; Orozco-Suarez, S; Ortiz-Plata, A; Pérez-Neri, I; Perez-Severiano, F; Ríos, C; Salgado-Ceballos, H; Zavala, C, 2008)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Dejban, P1
Rahimi, N1
Takzare, N1
Jahansouz, M1
Haddadi, NS1
Dehpour, AR1
Mahale, A1
Kumar, R1
Sarode, LP1
Gakare, S1
Prakash, A1
Ugale, RR1
Ogaki, S1
Taguchi, K1
Watanabe, H1
Ishima, Y1
Otagiri, M1
Maruyama, T1
Diaz-Ruiz, A2
Roldan-Valadez, E1
Ortiz-Plata, A2
Mondragón-Lozano, R1
Heras-Romero, Y1
Mendez-Armenta, M1
Osorio-Rico, L1
Nava-Ruiz, C2
Ríos, C2
Zavala, C1
Montes, S1
Salgado-Ceballos, H1
Orozco-Suarez, S1
Pérez-Neri, I1
Perez-Severiano, F1

Other Studies

5 other studies available for dapsone and Reperfusion Injury

ArticleYear
Beneficial effects of dapsone on ischemia/reperfusion injury following torsion/detorsion in ipsilateral and contralateral testes in rat.
    Theriogenology, 2019, Volume: 140

    Topics: Animals; Dapsone; Male; Rats; Rats, Wistar; Reactive Oxygen Species; Reperfusion Injury; Spermatic C

2019
Dapsone prolong delayed excitotoxic neuronal cell death by interacting with proapoptotic/survival signaling proteins.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2020, Volume: 29, Issue:8

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Brain; Cells, Cultured; Dapsone; Disease Models,

2020
Carbon monoxide-bound red blood cell resuscitation ameliorates hepatic injury induced by massive hemorrhage and red blood cell resuscitation via hepatic cytochrome P450 protection in hemorrhagic shock rats.
    Journal of pharmaceutical sciences, 2014, Volume: 103, Issue:7

    Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dapsone; Disease Models, Animal; Erythrocy

2014
Dapsone improves functional deficit and diminishes brain damage evaluated by 3-Tesla magnetic resonance image after transient cerebral ischemia and reperfusion in rats.
    Brain research, 2016, 09-01, Volume: 1646

    Topics: Animals; Brain; Brain Ischemia; Dapsone; Magnetic Resonance Imaging; Male; Neuroprotective Agents; N

2016
Antioxidant, antiinflammatory and antiapoptotic effects of dapsone in a model of brain ischemia/reperfusion in rats.
    Journal of neuroscience research, 2008, Nov-15, Volume: 86, Issue:15

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Brain Ischemia; Caspase 3; Caspase 9; Ch

2008