dapsone has been researched along with Malaria in 180 studies
Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlorproguanil-dapsone (CD) has been linked to hemolysis in symptomatic glucose-6-phosphate dehydrogenase deficient (G6PDd) children." | 9.20 | Risks of Hemolysis in Glucose-6-Phosphate Dehydrogenase Deficient Infants Exposed to Chlorproguanil-Dapsone, Mefloquine and Sulfadoxine-Pyrimethamine as Part of Intermittent Presumptive Treatment of Malaria in Infants. ( Alifrangis, M; Baraka, V; Carneiro, I; Chandramohan, D; Gesase, S; Gosling, R; Hashim, R; Ishengoma, D; Mosha, J; Poirot, E; Vittinghoff, E, 2015) |
| "Chlorproguanil-dapsone (Lapdap), developed as a low-cost antimalarial, was withdrawn in 2008 after concerns about safety in G6PD deficient patients." | 9.15 | Randomized trial of safety and effectiveness of chlorproguanil-dapsone and lumefantrine-artemether for uncomplicated malaria in children in the Gambia. ( Adiamoh, M; Bisseye, C; Cheung, YB; Conway, D; Diatta, M; Dunyo, S; Janha, R; Milligan, P; Njie, F; Nwakanma, D; Sesay, S; Sirugo, G; Sisay Joof, F; Snell, P; Temple, B; Walton, R, 2011) |
| "Pregnant women with non-severe, slide proven, falciparum malaria were randomised to one of 4 regimes: sulfadoxine-pyrimethamine [SP]; chlorproguanil-dapsone [CD]; SP+amodiaquine [SP+AQ] or amodiaquine+artesunate [AQ+AS]." | 9.14 | Randomized trial of artesunate+amodiaquine, sulfadoxine-pyrimethamine+amodiaquine, chlorproguanal-dapsone and SP for malaria in pregnancy in Tanzania. ( Briceño, M; Drakeley, C; Greenwood, BM; Mutabingwa, TK; Muze, K; Ord, R; Whitty, CJ, 2009) |
| "Sulphadoxine-pyrimethamine (SP) is the only single dose therapy for uncomplicated malaria, but there is widespread resistance." | 9.14 | Measurement of adherence, drug concentrations and the effectiveness of artemether-lumefantrine, chlorproguanil-dapsone or sulphadoxine-pyrimethamine in the treatment of uncomplicated malaria in Malawi. ( Bell, DJ; Chimpeni, P; Hughes, DA; Kayange, N; Lalloo, DG; Molyneux, ME; Montgomery, J; Mukaka, M; Ward, SA; Winstanley, PA; Wootton, D, 2009) |
| "Artesunate+amodiaquine (AS+AQ) and artemether-lumefantrine (AL) are now the most frequently recommended first line treatments for uncomplicated malaria in Africa." | 9.13 | An open label, randomised trial of artesunate+amodiaquine, artesunate+chlorproguanil-dapsone and artemether-lumefantrine for the treatment of uncomplicated malaria. ( Adjuik, M; Amenga-Etego, S; Asante, KP; Chandramohan, D; Dosoo, DK; Greenwood, B; Gyapong, J; Owusu, R; Owusu-Agyei, S, 2008) |
| "Two field trials to detect chloroquine-resistant malaria were conducted according to WHO recommendations in a malaria free area near Rangoon." | 9.04 | Chloroquine-resistant malaria in Burma. ( Hlaing, N; Htun Nyun, R; Kyi, KK; Myint, T; Tin, F; U, T, 1975) |
| "Randomized and quasi-randomized controlled trials comparing chlorproguanil-dapsone to other antimalarial drugs." | 8.82 | Chlorproguanil-dapsone for treating uncomplicated malaria. ( Bukirwa, H; Critchley, J; Garner, P, 2004) |
| "Resistance is readily produced in rodent malaria using the single-dose, '2%-relapse technique' (2%RT) against the individual compounds chlorproguanil (CPG), chlorcycloguanil (CCG), cycloguanil, dapsone (DDS) and artesunate (ASN)." | 7.73 | The chemotherapy of rodent malaria. LXIII. Drug combinations to impede the selection of drug resistance, part 6: the potential value of chlorproguanil and dapsone in combination, and with the addition of artesunate. ( Peters, W; Robinson, BL; Stewart, LB, 2005) |
| "The relative risks of non-specific upper respiratory tract infections were studied in two well matched groups of military recruits to see whether dapsone-pyrimethamine (Maloprim) given as antimalarial prophylaxis was associated with immunosuppression." | 7.67 | Risk of acute non-specific upper respiratory tract infections in healthy men taking dapsone-pyrimethamine for prophylaxis against malaria. ( Lau, EY; Lee, PS, 1988) |
| "A mechanism of action is proposed that encompasses almost all of the main categories of antimalarial agents: quinones and precursors, dapsone metabolites, metal complexes of thiosemicarbazones and biguanides, iminium-type ions from acridines and quinolines, and peroxides." | 7.67 | Charge transfer and oxy radicals in antimalarial action. Quinones, dapsone metabolites, metal complexes, iminium ions, and peroxides. ( Ames, JR; Klayman, DL; Kovacic, P; Ryan, MD, 1985) |
| "A reversed-phase high performance liquid chromatography method was developed to simultaneously estimate serum concentrations of dapsone (DDS), monoacetyldapsone (MADDS), and pyrimethamine (PYR) in 34 young adult Chinese men after they had taken the sixth weekly dose of Maloprim for malaria prophylaxis." | 7.67 | Simultaneous estimation of serum concentrations of dapsone, monoacetyldapsone, and pyrimethamine in Chinese men on maloprim for malaria prophylaxis using reversed-phase high performance liquid chromatography. ( Lee, HS; Lee, PS; Ti, TY; Yap, CL, 1985) |
| "The duration of protection from blood-stage malarial challenge following single injections of pyrimethamine pamoate was assessed in mice and monkeys." | 7.67 | Long-acting, repository antimalarial agents. Duration of protection in mice and monkeys following administration of pyrimethamine pamoate. ( Jacobs, RL; Steinkampf, RW; Werbel, LM; Worth, DF, 1984) |
| "There are no published haematological data on the long-term (more than one year) use of dapsone-pyrimethamine (Maloprim, Folaprim; one tablet a week) for malarial prophylaxis." | 7.67 | Haematological safety of long-term malarial prophylaxis with dapsone-pyrimethamine. ( Cook, IF; Kish, MY, 1985) |
| "Proguanil 200mg daily and chloroquine base 300mg weekly along with maloprim 1 tablet weekly was used as malaria chemoprophylaxis for 140 Hong Kong based soliders on a seven-week jungle exercise in a holoendemic malarial area of Papua New Guinea." | 7.67 | Malaria chemoprophylaxis with a proguanil-chloroquine-maloprim combination in Papua New Guinea. ( Heap, BJ, 1988) |
| "Malaria is a leading cause of mortality, particularly in sub-Saharan African children." | 6.77 | Glucose-6-phosphate dehydrogenase deficiency, chlorproguanil-dapsone with artesunate and post-treatment haemolysis in African children treated for uncomplicated malaria. ( Bassat, Q; D' Alessandro, U; Daniel, A; Forret, P; González, R; Machevo, S; Nabasumba, C; Piola, P; Robert, A; Talisuna, A; Turyakira, E; Van Geertruyden, JP; van Loen, H; Van Malderen, C; Van Overmeir, C; Yeka, A, 2012) |
| "Pyrimethamine alone was ineffective." | 6.64 | Single-dose therapy of Falciparum malaria using pyrimethamine in combination with diformyldapsone or sulfadoxine. ( Doberstyn, EB; Hall, AP; Sonkon, P; Vetvutanapibul, K, 1976) |
| "001) serum concentrations of PYR were found in Papua New Guineans than in Caucasians at both sampling times, an observation which may reflect differences in the bioavailability of PYR between the two racial groups." | 5.27 | Race-linked differences in serum concentrations of dapsone, monoacetyldapsone and pyrimethamine during malaria prophylaxis. ( Cochrane, JP; Cook, IF; Edstein, MD, 1986) |
| "Chlorproguanil-dapsone (CD) has been linked to hemolysis in symptomatic glucose-6-phosphate dehydrogenase deficient (G6PDd) children." | 5.20 | Risks of Hemolysis in Glucose-6-Phosphate Dehydrogenase Deficient Infants Exposed to Chlorproguanil-Dapsone, Mefloquine and Sulfadoxine-Pyrimethamine as Part of Intermittent Presumptive Treatment of Malaria in Infants. ( Alifrangis, M; Baraka, V; Carneiro, I; Chandramohan, D; Gesase, S; Gosling, R; Hashim, R; Ishengoma, D; Mosha, J; Poirot, E; Vittinghoff, E, 2015) |
| "Chlorproguanil-dapsone (Lapdap), developed as a low-cost antimalarial, was withdrawn in 2008 after concerns about safety in G6PD deficient patients." | 5.15 | Randomized trial of safety and effectiveness of chlorproguanil-dapsone and lumefantrine-artemether for uncomplicated malaria in children in the Gambia. ( Adiamoh, M; Bisseye, C; Cheung, YB; Conway, D; Diatta, M; Dunyo, S; Janha, R; Milligan, P; Njie, F; Nwakanma, D; Sesay, S; Sirugo, G; Sisay Joof, F; Snell, P; Temple, B; Walton, R, 2011) |
| "Intermittent preventive treatment in infants (IPTi) with sulphadoxine-pyrimethamine (SP) for the prevention of malaria has shown promising results in six trials." | 5.14 | Intermittent preventive treatment in infants for the prevention of malaria in rural Western kenya: a randomized, double-blind placebo-controlled trial. ( Hamel, MJ; Kariuki, S; Lindblade, K; Newman, RD; Odhiambo, FO; Otieno, P; Peterson, E; Slutsker, L; ter Kuile, FO; Vulule, J; Williamson, J, 2010) |
| "Pregnant women with non-severe, slide proven, falciparum malaria were randomised to one of 4 regimes: sulfadoxine-pyrimethamine [SP]; chlorproguanil-dapsone [CD]; SP+amodiaquine [SP+AQ] or amodiaquine+artesunate [AQ+AS]." | 5.14 | Randomized trial of artesunate+amodiaquine, sulfadoxine-pyrimethamine+amodiaquine, chlorproguanal-dapsone and SP for malaria in pregnancy in Tanzania. ( Briceño, M; Drakeley, C; Greenwood, BM; Mutabingwa, TK; Muze, K; Ord, R; Whitty, CJ, 2009) |
| "Sulphadoxine-pyrimethamine (SP) is the only single dose therapy for uncomplicated malaria, but there is widespread resistance." | 5.14 | Measurement of adherence, drug concentrations and the effectiveness of artemether-lumefantrine, chlorproguanil-dapsone or sulphadoxine-pyrimethamine in the treatment of uncomplicated malaria in Malawi. ( Bell, DJ; Chimpeni, P; Hughes, DA; Kayange, N; Lalloo, DG; Molyneux, ME; Montgomery, J; Mukaka, M; Ward, SA; Winstanley, PA; Wootton, D, 2009) |
| "Artesunate+amodiaquine (AS+AQ) and artemether-lumefantrine (AL) are now the most frequently recommended first line treatments for uncomplicated malaria in Africa." | 5.13 | An open label, randomised trial of artesunate+amodiaquine, artesunate+chlorproguanil-dapsone and artemether-lumefantrine for the treatment of uncomplicated malaria. ( Adjuik, M; Amenga-Etego, S; Asante, KP; Chandramohan, D; Dosoo, DK; Greenwood, B; Gyapong, J; Owusu, R; Owusu-Agyei, S, 2008) |
| "A cohort of 48 Gambian children was protected against malaria by fortnightly administration of Maloprim (pyrimethamine and dapsone) for 2 years between their 3 and 5 birthdays." | 5.06 | Immunity to malaria in young Gambian children after a two-year period of chemoprophylaxis. ( Byass, P; Greenwood, BM; Menon, A; Otoo, LN; Snow, RW, 1988) |
| "Two drug strategies for the control of malaria in children aged 3-59 months have been compared in a rural area of The Gambia--treatment of presumptive episodes of clinical malaria with chloroquine by village health workers, and treatment combined with fortnightly chemoprophylaxis with 'Maloprim' (pyrimethamine/dapsone) which was also given by village health workers." | 5.06 | Comparison of two strategies for control of malaria within a primary health care programme in the Gambia. ( Bradley, AK; Byass, P; Greenwood, AM; Greenwood, BM; Hayes, RJ; N'Jie, AB; Snow, RW, 1988) |
| "A battalion of Royal Thai Marine militia was assigned to take either 50 mg or 100 mg of doxycycline daily or pyrimethamine/dapsone weekly for malaria prophylaxis on the Thai-Kampuchean border for a 17 week period." | 5.06 | Malaria prophylaxis with doxycycline in soldiers deployed to the Thai-Kampuchean border. ( Karwacki, JJ; Phintuyothin, P; Pilungkasa, S; Shanks, D; Singharaj, P; Suriyamongkol, V; Wasuwat, P; Watanasook, C, 1989) |
| "We have reviewed a malaria chemoprophylaxis programme in which Maloprim (pyrimethamine and dapsone) has been administered fortnightly by village health workers (VHWs) to approximately 1500 children each year aged 6-59 months resident in 15 primary health care villages in a rural area of The Gambia over 5 years." | 5.06 | Compliance with malaria chemoprophylaxis over a five-year period among children in a rural area of The Gambia. ( Allen, SJ; Greenwood, BM; Menon, A; Snow, RW, 1990) |
| "Two field trials to detect chloroquine-resistant malaria were conducted according to WHO recommendations in a malaria free area near Rangoon." | 5.04 | Chloroquine-resistant malaria in Burma. ( Hlaing, N; Htun Nyun, R; Kyi, KK; Myint, T; Tin, F; U, T, 1975) |
| "In an area of Thailand where chloroquine-resistant falciparum malaria is known to exist, a chemosuppressive field trial was undertaken to test the efficacy of the preparation diformyldapsone (DFD) combined with pyrimethamine (Py) in suppressing falciparum and vivax parasitemias." | 5.04 | Chemosuppressive field trials in Thailand. II. The suppression of Plasmodium falciparum and Plasmodium vivax parasitemias by a diformyldapsone-pyrimethamine combination. ( Castaneda, BF; Pearlman, EJ; Thiemanun, W, 1975) |
| "From 1936 until 1996, the drug dapsone treated a diverse array of diseases, including tuberculosis, leprosy, malaria, and AIDS-related pneumonia." | 4.87 | A short history of dapsone, or an alternative model of drug development. ( Barr, J, 2011) |
| "Randomized and quasi-randomized controlled trials comparing chlorproguanil-dapsone to other antimalarial drugs." | 4.82 | Chlorproguanil-dapsone for treating uncomplicated malaria. ( Bukirwa, H; Critchley, J; Garner, P, 2004) |
| "From 1936 until 1996, the drug dapsone treated a diverse array of diseases, including tuberculosis, leprosy, malaria, and AIDS-related pneumonia." | 3.77 | A short history of dapsone, or an alternative model of drug development. ( Barr, J, 2011) |
| "Resistance is readily produced in rodent malaria using the single-dose, '2%-relapse technique' (2%RT) against the individual compounds chlorproguanil (CPG), chlorcycloguanil (CCG), cycloguanil, dapsone (DDS) and artesunate (ASN)." | 3.73 | The chemotherapy of rodent malaria. LXIII. Drug combinations to impede the selection of drug resistance, part 6: the potential value of chlorproguanil and dapsone in combination, and with the addition of artesunate. ( Peters, W; Robinson, BL; Stewart, LB, 2005) |
| " In this study the plasma metabolic ratios of proguanil and dapsone to their principal metabolites cycloguanil and monoacetyldapsone were determined in Thai soldiers receiving antifolate drug combinations for malaria prophylaxis." | 3.69 | Oxidative activation of proguanil and dapsone acetylation in Thai soldiers. ( Edstein, MD; Rieckmann, KH; Shanks, GD; Teja-Isavadharm, P; Webster, HK, 1994) |
| "Two soldiers continued weekly prophylaxis with 300 mg chloroquine base on their return to Australia from Papua New Guinea but were not protected against Plasmodium vivax malaria." | 3.67 | Plasmodium vivax resistance to chloroquine? ( Davis, DR; Hutton, DC; Rieckmann, KH, 1989) |
| "The relative risks of non-specific upper respiratory tract infections were studied in two well matched groups of military recruits to see whether dapsone-pyrimethamine (Maloprim) given as antimalarial prophylaxis was associated with immunosuppression." | 3.67 | Risk of acute non-specific upper respiratory tract infections in healthy men taking dapsone-pyrimethamine for prophylaxis against malaria. ( Lau, EY; Lee, PS, 1988) |
| "The duration of protection from blood-stage malarial challenge following single injections of pyrimethamine pamoate was assessed in mice and monkeys." | 3.67 | Long-acting, repository antimalarial agents. Duration of protection in mice and monkeys following administration of pyrimethamine pamoate. ( Jacobs, RL; Steinkampf, RW; Werbel, LM; Worth, DF, 1984) |
| "Proguanil 200mg daily and chloroquine base 300mg weekly along with maloprim 1 tablet weekly was used as malaria chemoprophylaxis for 140 Hong Kong based soliders on a seven-week jungle exercise in a holoendemic malarial area of Papua New Guinea." | 3.67 | Malaria chemoprophylaxis with a proguanil-chloroquine-maloprim combination in Papua New Guinea. ( Heap, BJ, 1988) |
| "A reversed-phase high performance liquid chromatography method was developed to simultaneously estimate serum concentrations of dapsone (DDS), monoacetyldapsone (MADDS), and pyrimethamine (PYR) in 34 young adult Chinese men after they had taken the sixth weekly dose of Maloprim for malaria prophylaxis." | 3.67 | Simultaneous estimation of serum concentrations of dapsone, monoacetyldapsone, and pyrimethamine in Chinese men on maloprim for malaria prophylaxis using reversed-phase high performance liquid chromatography. ( Lee, HS; Lee, PS; Ti, TY; Yap, CL, 1985) |
| "Several drugs are used for malaria chemoprophylaxis: 4 amino-quinolines, antifolics, combinations of sulfonamides and antifolics, and new anti-malarial agents, including mefloquine." | 3.67 | [Malaria chemoprophylaxis. Resistance problems]. ( Danis, M; Gentilini, M, 1985) |
| "There are no published haematological data on the long-term (more than one year) use of dapsone-pyrimethamine (Maloprim, Folaprim; one tablet a week) for malarial prophylaxis." | 3.67 | Haematological safety of long-term malarial prophylaxis with dapsone-pyrimethamine. ( Cook, IF; Kish, MY, 1985) |
| "A mechanism of action is proposed that encompasses almost all of the main categories of antimalarial agents: quinones and precursors, dapsone metabolites, metal complexes of thiosemicarbazones and biguanides, iminium-type ions from acridines and quinolines, and peroxides." | 3.67 | Charge transfer and oxy radicals in antimalarial action. Quinones, dapsone metabolites, metal complexes, iminium ions, and peroxides. ( Ames, JR; Klayman, DL; Kovacic, P; Ryan, MD, 1985) |
| "As part of the search for new antimalarial drugs, a screening program was developed using sensitive and chlorguanide triazine (CGT, cycloguanil) resistant strains of the folate-requiring bacteria, Streptococcus faecium durans, Lactobacillus casei, and Pediococcus cerevisiae." | 3.65 | Antifolate studies. Activities of 40 potential antimalarial compounds against sensitive and chlorguanide triazine resistant strains of folate-requiring bacteria and Escherichia coli. ( Genther, CS; Smith, CS, 1977) |
| "Malaria is a leading cause of mortality, particularly in sub-Saharan African children." | 2.77 | Glucose-6-phosphate dehydrogenase deficiency, chlorproguanil-dapsone with artesunate and post-treatment haemolysis in African children treated for uncomplicated malaria. ( Bassat, Q; D' Alessandro, U; Daniel, A; Forret, P; González, R; Machevo, S; Nabasumba, C; Piola, P; Robert, A; Talisuna, A; Turyakira, E; Van Geertruyden, JP; van Loen, H; Van Malderen, C; Van Overmeir, C; Yeka, A, 2012) |
| "Pyrimethamine alone was ineffective." | 2.64 | Single-dose therapy of Falciparum malaria using pyrimethamine in combination with diformyldapsone or sulfadoxine. ( Doberstyn, EB; Hall, AP; Sonkon, P; Vetvutanapibul, K, 1976) |
| "Prophylaxis and intermittent treatment with antimalarial drugs reduce clinical malaria and severe anaemia in preschool children." | 2.43 | Chemoprophylaxis and intermittent treatment for preventing malaria in children. ( Garner, P; Meremikwu, MM; Omari, AA, 2005) |
| "Although malaria has been widely eradicated in many parts of the world, the global number of cases continues to rise." | 2.42 | New antimalarial drugs. ( Jomaa, H; Ortmann, R; Schlitzer, M; Wiesner, J, 2003) |
| " Safe and effective drugs, capable of being administered as a single-dose or short-course treatment, are urgently needed to control the adaptable malaria parasite." | 2.36 | Falciparum malaria: the urgent need for safe and effective drugs. ( Rieckmann, KH, 1983) |
| "Early childhood malaria is often fatal, but its impact on the development and education of survivors has not received much attention." | 1.40 | Early childhood malaria prevention and children's patterns of school leaving in the Gambia. ( Jukes, MC; Zuilkowski, SS, 2014) |
| ") was tested alone, or in a double and triple combination with a fixed oral dose of 1." | 1.35 | Plasmodium berghei: efficacy of 5-fluoroorotate in combination with commonly used antimalarial drugs in a mouse model. ( Ishih, A; Kano, S; Kino, H; Muregi, FW, 2009) |
| "Chloroquine plus Maloprim was used significantly more by general practitioners in older age groups, ie 45 years and over (p < 0." | 1.30 | Malaria prophylaxis prescribed for travellers from New Zealand. ( Heydon, JL; Leggat, PA; Menon, A, 1997) |
| "In The Gambia, insecticide impregnation of bed nets, used alone or combined with Maloprim, reduced morbidity and mortality from malaria amongst children between one and 4 years of age." | 1.29 | A malaria control trial using insecticide-treated bed nets and targeted chemoprophylaxis in a rural area of The Gambia, west Africa. 8. Cost-effectiveness of bed net impregnation alone or combined with chemoprophylaxis in preventing mortality and morbidit ( Aikins, M; Alonso, PL; Armstrong Schellenberg, JR; Greenwood, BM; Mills, A; Picard, J, 1993) |
| "Blood induced Plasmodium berghei infection in Swiss mice was exposed during successive passages to melfloquine alone or melfoquine in combination with dapsone or primaquine or erythromycin, and the level of resistance to melfoquine in four sub-lines was compared at ED90 level." | 1.28 | Delay in emergence of mefloquine resistance in Plasmodium berghei by use of drug combinations. ( Dutta, GP; Puri, SK, 1989) |
| "001) serum concentrations of PYR were found in Papua New Guineans than in Caucasians at both sampling times, an observation which may reflect differences in the bioavailability of PYR between the two racial groups." | 1.27 | Race-linked differences in serum concentrations of dapsone, monoacetyldapsone and pyrimethamine during malaria prophylaxis. ( Cochrane, JP; Cook, IF; Edstein, MD, 1986) |
| "A high-performance liquid chromatographic method was developed to enable dapsone, monoacetyl dapsone and pyrimethamine to be measured simultaneously in plasma samples from volunteers in England and Malaysia who had been dosed with Maloprim." | 1.26 | Determination of plasma concentrations of dapsone, monoacetyl dapsone and pyrimethamine in human subjects dosed with maloprim. ( Jones, CR; Ovenell, SM, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 145 (80.56) | 18.7374 |
| 1990's | 14 (7.78) | 18.2507 |
| 2000's | 11 (6.11) | 29.6817 |
| 2010's | 9 (5.00) | 24.3611 |
| 2020's | 1 (0.56) | 2.80 |
| Authors | Studies |
|---|---|
| Genther, CS | 1 |
| Smith, CS | 1 |
| Tibon, NS | 1 |
| Ng, CH | 1 |
| Cheong, SL | 1 |
| Zuilkowski, SS | 1 |
| Jukes, MC | 1 |
| Barr, J | 2 |
| Poirot, E | 1 |
| Vittinghoff, E | 1 |
| Ishengoma, D | 1 |
| Alifrangis, M | 1 |
| Carneiro, I | 2 |
| Hashim, R | 2 |
| Baraka, V | 1 |
| Mosha, J | 1 |
| Gesase, S | 2 |
| Chandramohan, D | 3 |
| Gosling, R | 2 |
| Owusu-Agyei, S | 1 |
| Asante, KP | 1 |
| Owusu, R | 1 |
| Adjuik, M | 1 |
| Amenga-Etego, S | 1 |
| Dosoo, DK | 1 |
| Gyapong, J | 1 |
| Greenwood, B | 3 |
| Muregi, FW | 1 |
| Kano, S | 1 |
| Kino, H | 1 |
| Ishih, A | 1 |
| Mutabingwa, TK | 1 |
| Muze, K | 1 |
| Ord, R | 1 |
| Briceño, M | 1 |
| Greenwood, BM | 9 |
| Drakeley, C | 1 |
| Whitty, CJ | 1 |
| Bell, DJ | 1 |
| Wootton, D | 1 |
| Mukaka, M | 1 |
| Montgomery, J | 1 |
| Kayange, N | 1 |
| Chimpeni, P | 1 |
| Hughes, DA | 1 |
| Molyneux, ME | 1 |
| Ward, SA | 1 |
| Winstanley, PA | 1 |
| Lalloo, DG | 1 |
| Cairns, M | 1 |
| Mosha, JF | 1 |
| Kaur, H | 1 |
| Lemnge, M | 1 |
| Mosha, FW | 1 |
| Odhiambo, FO | 1 |
| Hamel, MJ | 1 |
| Williamson, J | 1 |
| Lindblade, K | 1 |
| ter Kuile, FO | 1 |
| Peterson, E | 1 |
| Otieno, P | 1 |
| Kariuki, S | 1 |
| Vulule, J | 1 |
| Slutsker, L | 1 |
| Newman, RD | 1 |
| Dunyo, S | 1 |
| Sirugo, G | 1 |
| Sesay, S | 1 |
| Bisseye, C | 1 |
| Njie, F | 1 |
| Adiamoh, M | 1 |
| Nwakanma, D | 1 |
| Diatta, M | 1 |
| Janha, R | 1 |
| Sisay Joof, F | 1 |
| Temple, B | 1 |
| Snell, P | 1 |
| Conway, D | 1 |
| Walton, R | 1 |
| Cheung, YB | 1 |
| Milligan, P | 1 |
| Van Malderen, C | 1 |
| Van Geertruyden, JP | 1 |
| Machevo, S | 1 |
| González, R | 1 |
| Bassat, Q | 1 |
| Talisuna, A | 1 |
| Yeka, A | 1 |
| Nabasumba, C | 1 |
| Piola, P | 1 |
| Daniel, A | 1 |
| Turyakira, E | 1 |
| Forret, P | 1 |
| Van Overmeir, C | 1 |
| van Loen, H | 1 |
| Robert, A | 1 |
| D' Alessandro, U | 1 |
| Donegan, S | 1 |
| Williamson, P | 1 |
| D'Alessandro, U | 1 |
| Tudur Smith, C | 1 |
| RAMAKRISHNAN, SP | 1 |
| BASU, PC | 2 |
| SINGH, H | 1 |
| SINGH, N | 2 |
| SINGH, NN | 1 |
| THOMPSON, PE | 1 |
| OLSZEWSKI, B | 1 |
| WAITZ, JA | 1 |
| Wiesner, J | 1 |
| Ortmann, R | 1 |
| Jomaa, H | 1 |
| Schlitzer, M | 1 |
| Bukirwa, H | 1 |
| Garner, P | 2 |
| Critchley, J | 1 |
| Peters, W | 9 |
| Stewart, LB | 1 |
| Robinson, BL | 1 |
| Meremikwu, MM | 1 |
| Omari, AA | 1 |
| Edwards, G | 1 |
| Biagini, GA | 1 |
| Nyunt, MM | 1 |
| Plowe, CV | 1 |
| Sheehy, TW | 2 |
| Reba, RC | 2 |
| Clyde, DF | 8 |
| Most, H | 1 |
| Herman, R | 1 |
| Schoenfeld, C | 1 |
| McLarty, DG | 1 |
| Webber, RH | 1 |
| Jaatinen, M | 1 |
| Kihamia, CH | 1 |
| Murru, M | 1 |
| Kumano, M | 1 |
| Aubert, B | 1 |
| Magnuson, LW | 1 |
| Werbel, LM | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Non-Inferiority, Open-Labelled, Randomised Trial Of The Efficacy And Safety Of Artesunate-Amodiaquine, Artemether-Lumefantrine, And Artesunate-Lapdap For Treatment Of Uncomplicated P. Falciparum Malaria Among Children In Ghana[NCT00119145] | Phase 4 | 510 participants (Anticipated) | Interventional | 2005-06-30 | Completed | ||
| Treating Malaria During Pregnancy: A Randomized Trial of Potential Options for Treatment in an Area of High Drug Resistance in Tanzania[NCT00146731] | Phase 3 | 310 participants (Actual) | Interventional | 2004-01-31 | Completed | ||
| Drug Options for Intermittent Preventive Treatment for Malaria in Infants in an Area With High Resistance to Sulfadoxine/Pyrimethamine: an Evaluation of Short and Long-acting Antimalarial Drugs[NCT00158574] | Phase 2/Phase 3 | 2,419 participants (Actual) | Interventional | 2005-01-31 | Completed | ||
| Efficacy and Safety of Pediatric Immunization-linked Preventive Intermittent Treatment With Antimalarials in Decreasing Anemia and Malaria Morbidity in Rural Western Kenya[NCT00111163] | 1,516 participants | Interventional | 2004-03-31 | Completed | |||
| Randomized Trial of the Safety and Effectiveness of Lapdap and Coartemether for Uncomplicated Malaria in Operational Settings[NCT00118794] | Phase 3 | 1,200 participants | Interventional | 2004-09-30 | Completed | ||
| Neuroprotective Effect of Dapsone in Patients With Aneurysmal Subarachnoid Hemorrhage: Prospective, Randomized, Double-Blinded, Placebo-Controlled, Clinical Trial[NCT05131295] | Phase 3 | 49 participants (Actual) | Interventional | 2007-09-05 | Completed | ||
| Pharmacokinetics of Chlorproguanil-Dapsone in Pregnant Women With Plasmodium Falciparum Infection, and Reinfection With P. Falciparum During Pregnancy Following Treatment[NCT00126971] | Phase 1 | 132 participants | Interventional | 2005-07-31 | Suspended | ||
| Efficacy of Chloroquine (CQ) Alone Compared to Concomitant CQ and Primaquine (PQ) for the Treatment of Uncomplicated Plasmodium Vivax Infection[NCT02691910] | Phase 2/Phase 3 | 204 participants (Actual) | Interventional | 2014-08-31 | Completed | ||
| A Longitudinal Study Assessing the Infectious Status and Immunity of Mothers and Their Children in Lambaréné, Including Intermittent Treatment of Children With Sulfadoxine-pyrimethamine for Malaria Control and Its Impact on Long-term Health[NCT00167843] | Phase 4 | 1,189 participants | Interventional | 2002-12-31 | Completed | ||
| Comparison of Two Strategies for Control of Malaria Within A Primary Health Care Programme in the Gambia[NCT00294580] | Phase 4 | 2,253 participants | Interventional | 1982-04-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
19 reviews available for dapsone and Malaria
| Article | Year |
|---|---|
Current progress in antimalarial pharmacotherapy and multi-target drug discovery.
Topics: Animals; Antimalarials; Artemisinins; Drug Discovery; Drug Resistance; Humans; Malaria; Molecular St | 2020 |
A short history of dapsone, or an alternative model of drug development.
Topics: Antimalarials; Dapsone; Drug Industry; History, 20th Century; Humans; Leprostatic Agents; Leprosy; M | 2011 |
New antimalarial drugs.
Topics: Aminoquinolines; Animals; Antimalarials; Artemisinins; Artesunate; Atovaquone; Clinical Trials as To | 2003 |
Chlorproguanil-dapsone for treating uncomplicated malaria.
Topics: Adult; Antimalarials; Child; Dapsone; Drug Combinations; Humans; Malaria; Proguanil; Randomized Cont | 2004 |
Chemoprophylaxis and intermittent treatment for preventing malaria in children.
Topics: Antimalarials; Child, Preschool; Chloroquine; Dapsone; Humans; Infant; Malaria; Pyrimethamine; Rando | 2005 |
Resisting resistance: dealing with the irrepressible problem of malaria.
Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Dapsone; Drug Combinations; Drug Resistance; H | 2006 |
Falciparum malaria: the urgent need for safe and effective drugs.
Topics: Amodiaquine; Anti-Bacterial Agents; Antimalarials; Dapsone; Drug Combinations; Humans; Malaria; Plas | 1983 |
Malaria 1984. Part I. Malaria prophylaxis.
Topics: Antimalarials; Chloroquine; Dapsone; Drug Combinations; Drug Resistance, Microbial; Female; Humans; | 1984 |
Recent work concerning anemia in the tropics.
Topics: Adolescent; Adult; Anemia; Anemia, Hypochromic; Anemia, Megaloblastic; Animals; Child; Child, Presch | 1982 |
Drug interactions with antimalarial agents.
Topics: Antimalarials; Dapsone; Drug Interactions; Humans; Malaria; Proguanil; Pyrimethamine; Quinolines; Su | 1999 |
Malaria chemoprophylaxis: an update.
Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Child, Preschool; Dapsone; Drug Combinations; Female; | 1987 |
The chemoprophylaxis of malaria.
Topics: Amodiaquine; Animals; Chloroquine; Dapsone; Drug Combinations; Drug Resistance; Malaria; Plasmodium | 1987 |
Chemoprophylaxis of malaria.
Topics: Adolescent; Adult; Africa; Anemia, Hemolytic; Asia; Australia; Child; Child, Preschool; Chloroquine; | 1986 |
The problem of drug resistance in malaria.
Topics: Africa; Animals; Antimalarials; Artemisinins; Chemical Phenomena; Chemistry; Chloroquine; Clinical T | 1985 |
Summary of recent abstracts. 3. Malaria. 2.
Topics: Animals; Antimalarials; Birds; Chloroquine; Dapsone; Humans; India; Malaria; Malaria, Avian; Mammals | 1972 |
Summary of recent abstracts. 3. Malaria.2.
Topics: Animals; Carbon Isotopes; Chloroquine; Dapsone; DNA; Drug Resistance, Microbial; Humans; Malaria; Or | 1973 |
New perspectives on the chemotherapy of malaria, filariasis, and leprosy.
Topics: Amodiaquine; Aniline Compounds; Antimalarials; Chloroquine; Cresols; Dapsone; Drug Resistance; Filar | 1974 |
The pharmacology of the antimalarials. A rational approach to the therapy of resistant falciparum malaria.
Topics: Amodiaquine; Antimalarials; Chemical Phenomena; Chemistry; Chloroquine; Dapsone; Drug Resistance, Mi | 1969 |
Malaria. Chemoprophylaxis and chemotherapy.
Topics: Amodiaquine; Antimalarials; Chloroquine; Dapsone; Drug Resistance, Microbial; Drug Synergism; Humans | 1971 |
35 trials available for dapsone and Malaria
| Article | Year |
|---|---|
Risks of Hemolysis in Glucose-6-Phosphate Dehydrogenase Deficient Infants Exposed to Chlorproguanil-Dapsone, Mefloquine and Sulfadoxine-Pyrimethamine as Part of Intermittent Presumptive Treatment of Malaria in Infants.
Topics: Antimalarials; Cohort Studies; Dapsone; Double-Blind Method; Drug Combinations; Female; Genotype; Gl | 2015 |
An open label, randomised trial of artesunate+amodiaquine, artesunate+chlorproguanil-dapsone and artemether-lumefantrine for the treatment of uncomplicated malaria.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Child, Preschool; Dapsone; | 2008 |
Randomized trial of artesunate+amodiaquine, sulfadoxine-pyrimethamine+amodiaquine, chlorproguanal-dapsone and SP for malaria in pregnancy in Tanzania.
Topics: Adult; Amodiaquine; Artemisinins; Artesunate; Dapsone; Drug Combinations; Drug Therapy, Combination; | 2009 |
Measurement of adherence, drug concentrations and the effectiveness of artemether-lumefantrine, chlorproguanil-dapsone or sulphadoxine-pyrimethamine in the treatment of uncomplicated malaria in Malawi.
Topics: Adolescent; Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Ch | 2009 |
Duration of protection against clinical malaria provided by three regimens of intermittent preventive treatment in Tanzanian infants.
Topics: Antimalarials; Dapsone; Drug Administration Schedule; Drug Combinations; Drug Resistance; Humans; Im | 2010 |
Intermittent preventive treatment in infants for the prevention of malaria in rural Western kenya: a randomized, double-blind placebo-controlled trial.
Topics: Anemia; Antimalarials; Artemisinins; Artesunate; Dapsone; Double-Blind Method; Drug Combinations; Hu | 2010 |
Randomized trial of safety and effectiveness of chlorproguanil-dapsone and lumefantrine-artemether for uncomplicated malaria in children in the Gambia.
Topics: Animals; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Aryl Hydrocarbon Hy | 2011 |
Glucose-6-phosphate dehydrogenase deficiency, chlorproguanil-dapsone with artesunate and post-treatment haemolysis in African children treated for uncomplicated malaria.
Topics: Africa South of the Sahara; Anemia, Hemolytic; Antimalarials; Artemisinins; Artesunate; Case-Control | 2012 |
Malaria chemoprophylaxis, infection of the placenta and birth weight in Gambian primigravidae.
Topics: Acute Disease; Antimalarials; Birth Weight; Chronic Disease; Dapsone; Double-Blind Method; Drug Comb | 1994 |
Controlled trial of lambda-cyhalothrin impregnated bed nets and Maloprim chemosuppression to control malaria in children living in a holoendemic area of Sierra Leone, west Africa. Study design and preliminary results.
Topics: Animals; Anopheles; Bedding and Linens; Child; Child, Preschool; Dapsone; Double-Blind Method; Drug | 1993 |
Chloroquine-resistant malaria in Burma.
Topics: Chloroquine; Clinical Trials as Topic; Dapsone; Drug Resistance, Microbial; Humans; Malaria; Myanmar | 1975 |
Chemosuppressive field trials in Thailand. III. The suppression of Plasmodium falciparum and Plasmodium vivax parasitemias by a sulfadoxine-pyrimethamine combination.
Topics: Blood; Clinical Trials as Topic; Dapsone; Drug Combinations; Female; Humans; Malaria; Male; Plasmodi | 1977 |
Single-dose therapy of Falciparum malaria using pyrimethamine in combination with diformyldapsone or sulfadoxine.
Topics: Adolescent; Adult; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Evaluation; Humans; Ma | 1976 |
Comparison of diaminodiphenylsulphonepyrimethamine and sulfadoxine-pyrimethamine combinations in the treatment of falciparum malaria in Thailand.
Topics: Adolescent; Adult; Dapsone; Drug Evaluation; Drug Synergism; Female; Humans; Malaria; Male; Middle A | 1975 |
Malaria prophylaxis.
Topics: Chloroquine; Dapsone; Drug Combinations; Humans; Malaria; Military Medicine; Plasmodium falciparum; | 1975 |
Chemosuppressive field trials in Thailand. II. The suppression of Plasmodium falciparum and Plasmodium vivax parasitemias by a diformyldapsone-pyrimethamine combination.
Topics: Adolescent; Adult; Aged; Antimalarials; Child; Dapsone; Drug Administration Schedule; Drug Evaluatio | 1975 |
The effect of insecticide-treated bed nets on mortality of Gambian children.
Topics: Antimalarials; Bedding and Linens; Child, Preschool; Community Health Workers; Dapsone; Drug Adminis | 1991 |
Proguanil/sulfamethoxazole malaria chemoprophy-laxis on the Thai-Cambodian border.
Topics: Adult; Animals; Cambodia; Dapsone; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Male | 1991 |
Comparison of chloroquine, pyrimethamine and sulfadoxine, and chlorproguanil and dapsone as treatment for falciparum malaria in pregnant and non-pregnant women, Kakamega District, Kenya.
Topics: Adolescent; Adult; Animals; Antimalarials; Chloroquine; Dapsone; Drug Therapy, Combination; Female; | 1990 |
Compliance with malaria chemoprophylaxis over a five-year period among children in a rural area of The Gambia.
Topics: Antimalarials; Attitude of Health Personnel; Attitude to Health; Child, Preschool; Community Health | 1990 |
Malaria prophylaxis with doxycycline in soldiers deployed to the Thai-Kampuchean border.
Topics: Antimalarials; Dapsone; Dose-Response Relationship, Drug; Doxycycline; Drug Combinations; Drug Evalu | 1989 |
Comparison of two strategies for control of malaria within a primary health care programme in the Gambia.
Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Community Health Workers; Dapsone; Drug Combina | 1988 |
Comparison of two strategies for control of malaria within a primary health care programme in the Gambia.
Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Community Health Workers; Dapsone; Drug Combina | 1988 |
Comparison of two strategies for control of malaria within a primary health care programme in the Gambia.
Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Community Health Workers; Dapsone; Drug Combina | 1988 |
Comparison of two strategies for control of malaria within a primary health care programme in the Gambia.
Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Community Health Workers; Dapsone; Drug Combina | 1988 |
Immunity to malaria in young Gambian children after a two-year period of chemoprophylaxis.
Topics: Animals; Antibodies, Protozoan; Antigens, Protozoan; Antimalarials; Child, Preschool; Cohort Studies | 1988 |
Chlorproguanil/dapsone for the treatment of non-severe Plasmodium falciparum malaria in Kenya: a pilot study.
Topics: Animals; Dapsone; Drug Therapy, Combination; Humans; Kenya; Malaria; Pilot Projects; Plasmodium falc | 1988 |
The problem of drug resistance in malaria.
Topics: Africa; Animals; Antimalarials; Artemisinins; Chemical Phenomena; Chemistry; Chloroquine; Clinical T | 1985 |
A field trial of pyrimethamine combined with dapsone in the chemoprophylaxis of malaria.
Topics: Clinical Trials as Topic; Dapsone; Drug Therapy, Combination; Humans; Malaria; Plasmodium falciparum | 1972 |
Combinations of 4-aminobenzoic acid competitors and dihydrofolate dehydrogenase inhibitors in the chemotherapy of malaria. A commentary.
Topics: Africa; Antimalarials; Asia; Chloroquine; Clinical Trials as Topic; Dapsone; Drug Evaluation; Drug R | 1974 |
The suppression of malarial parasitaemia by pyrimethamine in combination with dapsone or sulphormethoxine.
Topics: Adolescent; Antimalarials; Blood; Child; Clinical Trials as Topic; Dapsone; Escherichia coli; Feces; | 1969 |
Studies on the chemotherapy of malaria. I. The treatment of overt falciparum malaria with potentiating combinations of pyrimethamine and sulphormethoxine or dapsone in The Gambia.
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Dapsone; Drug Resistan | 1970 |
Prophylactic and sporontocidal treatment of chloroquine resistant Plasmodium falciparum from Malaya.
Topics: Adult; Amodiaquine; Anopheles; Antimalarials; Blood; Chloroquine; Clinical Trials as Topic; Dapsone; | 1970 |
Prophylactic and sporontocidal treatment of chloroquine-resistant Plasmodium falciparum from Vietnam.
Topics: Adult; Antimalarials; Chloroquine; Clinical Trials as Topic; Dapsone; Humans; Malaria; Male; Methemo | 1971 |
Malaria chemoprophylaxis with 4,4' diaminodiphenylsulfone (DDS). I. Field trial with comparison among companies of one division.
Topics: Antimalarials; Clinical Trials as Topic; Dapsone; Humans; Malaria; Male; Military Medicine; United S | 1969 |
Malaria chemoprophylaxis with 4,4' diaminodiphenylsulfone (DDS). II. Field trial with comparison between two divisions.
Topics: Antimalarials; Clinical Trials as Topic; Dapsone; Humans; Malaria; Male; Military Medicine; United S | 1969 |
Diformyl diaminodiphenyl sufone (DFD) as an antimalarial in man.
Topics: Adult; Antimalarials; Chloroquine; Clinical Trials as Topic; Dapsone; Formates; Humans; Malaria; Mal | 1970 |
The evaluation of quinine sulfate and diaminodiphenyl sulfone (DDS) as suppressive agents against sporozoite-induced Chesson strain vivax malaria.
Topics: Clinical Trials as Topic; Dapsone; Humans; Malaria; Plasmodium vivax; Quinine | 1966 |
127 other studies available for dapsone and Malaria
| Article | Year |
|---|---|
Antifolate studies. Activities of 40 potential antimalarial compounds against sensitive and chlorguanide triazine resistant strains of folate-requiring bacteria and Escherichia coli.
Topics: Animals; Antimalarials; Bacteria; Drug Resistance, Microbial; Escherichia coli; Folic Acid; Folic Ac | 1977 |
Early childhood malaria prevention and children's patterns of school leaving in the Gambia.
Topics: Adolescent; Antimalarials; Child; Dapsone; Drug Combinations; Early Medical Intervention; Female; Fo | 2014 |
A short history of dapsone, or an alternative model of drug development.
Topics: Antimalarials; Antitubercular Agents; Dapsone; History, 20th Century; Humans; Leprostatic Agents; Le | 2011 |
Plasmodium berghei: efficacy of 5-fluoroorotate in combination with commonly used antimalarial drugs in a mouse model.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Dapsone; Drug Synergism; Drug Therapy, Combination | 2009 |
Assessing the consistency assumption by exploring treatment by covariate interactions in mixed treatment comparison meta-analysis: individual patient-level covariates versus aggregate trial-level covariates.
Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Dap | 2012 |
Studies on the toxicity and action of diaminodiphenyl-sulfone (DDS) in avian and simian malaria.
Topics: Animals; Antimalarials; Birds; Chloroquine; Dapsone; Malaria; Malaria, Avian; Proguanil; Pyrimethami | 1962 |
POTENTIATION OF ACTIVITY OF DIAPHENYLSULFONE AND PYRIMETHAMINE AGAINST PLASMODIUM GALLINACEUM AND PLASMODIUM CYNOMOLGI BASTIANELLII.
Topics: Animals; Dapsone; Drug Resistance; Drug Resistance, Microbial; Haplorhini; Malaria; Pharmacology; Pl | 1964 |
LABORATORY STUDIES ON THE REPOSITORY ANTIMALARIAL ACTIVITY OF 4,4'-DIACETYLAMINODIPHENYLSULFONE, ALONE AND MIXED WITH CYCLOGUANIL PAMOATE (CI-501).
Topics: Animals; Antimalarials; Dapsone; Haplorhini; Malaria; Mice; Pharmacology; Proguanil; Research; Triaz | 1965 |
The chemotherapy of rodent malaria. LXIII. Drug combinations to impede the selection of drug resistance, part 6: the potential value of chlorproguanil and dapsone in combination, and with the addition of artesunate.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Dapsone; Drug Resistance; Drug Synergism; Drug The | 2005 |
Pharmacologic advances in the global control and treatment of malaria: combination therapy and resistance.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Dapsone; Drug Design; | 2007 |
Treatment of chloroquine-resistant Plasmodium falciparum infections in Vietnam.
Topics: Chloroquine; Dapsone; Humans; Malaria; Military Medicine; Pyrimethamine; Quinacrine; Quinine; Sulfad | 1967 |
Antimalarial effect of diaphenylsulfone and three sulfonamides among semi-immune Africans.
Topics: Adolescent; Black or African American; Black People; Child; Dapsone; Humans; Immunity; Malaria; Sulf | 1967 |
Chemotherapy of sporozoite- and blood-induced Plasmodium berghei infections with selected antimalarial agents.
Topics: Animals; Chloroquine; Cricetinae; Dapsone; Malaria; Mice; Primaquine; Pyrimethamine; Quinine; Rats | 1967 |
Reactions to dapsone.
Topics: Agranulocytosis; Dapsone; Drug Combinations; Humans; Malaria; Medication Errors; Pyrimethamine | 1981 |
Chemoprophylaxis of malaria in non-immune residents in Dar es Salaam, Tanzania.
Topics: Adolescent; Adult; Aged; Antimalarials; Child; Child, Preschool; Chloroquine; Dapsone; Drug Administ | 1984 |
Long-acting, repository antimalarial agents. Duration of protection in mice and monkeys following administration of pyrimethamine pamoate.
Topics: Acedapsone; Animals; Dapsone; Drug Combinations; Female; Injections, Intramuscular; Macaca fascicula | 1984 |
Treatment of falciparum malaria with a single dose combination of dapsone and pyrimethamine (Maloprim).
Topics: Adolescent; Adult; Antimalarials; Child; Child, Preschool; Dapsone; Drug Combinations; Female; Human | 1983 |
Malaria chemoprophylaxis--which drug?
Topics: Adult; Antimalarials; Child, Preschool; Chloroquine; Dapsone; Drug Combinations; Drug Resistance, Mi | 1983 |
Activities of respository preparations of cycloguanil pamoate and 4,4'-diacetyldiaminodiphenylsulfone, alone and in combination, against infections with Plasmodium cynomolgi in rhesus monkeys.
Topics: Acedapsone; Animals; Antimalarials; Dapsone; Drug Combinations; Drug Resistance, Microbial; Macaca m | 1984 |
Malaria in Christchurch.
Topics: Chloroquine; Dapsone; Drug Combinations; Humans; Malaria; New Zealand; Plasmodium falciparum; Plasmo | 1984 |
Chemoprophylaxis of malaria in Africa.
Topics: Agranulocytosis; Antimalarials; Dapsone; Drug Combinations; Humans; Malaria; Male; Middle Aged; Pyri | 1983 |
Agranulocytosis associated with malaria prophylaxis with Maloprim.
Topics: Adult; Aged; Agranulocytosis; Antimalarials; Dapsone; Drug Combinations; Female; Humans; Malaria; Ma | 1983 |
Agranulocytosis associated with Maloprim.
Topics: Aged; Agranulocytosis; Dapsone; Drug Combinations; Female; Humans; Malaria; Middle Aged; Pyrimethami | 1983 |
Malaria prophylaxis for long term visitors.
Topics: Antimalarials; Chloroquine; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; | 1983 |
Maloprim--general toxicity or idiosyncrasy?
Topics: Adult; Agranulocytosis; Dapsone; Drug Combinations; Female; Humans; Malaria; Pyrimethamine | 1984 |
Red cell hypoplasia following dapsone and pyrimethamine.
Topics: Aged; Anemia, Aplastic; Dapsone; Humans; Malaria; Male; Pyrimethamine | 1983 |
Malaria incidence in leprosy patients under dapsone therapy in Karbi-Anglong district, Assam.
Topics: Adult; Antimalarials; Child; Dapsone; Humans; India; Leprosy; Malaria; Plasmodium falciparum | 1982 |
Drug prevention of malaria.
Topics: Dapsone; Drug Combinations; Humans; Malaria; Pyrimethamine | 1981 |
Treatment of malaria.
Topics: Dapsone; Drug Therapy, Combination; Humans; Malaria; Primaquine; Pyrimethamine | 1980 |
Malaria in southeast Queensland in 1979.
Topics: Adolescent; Adult; Australia; Child; Child, Preschool; Chloroquine; Dapsone; Female; Humans; Infant; | 1980 |
Malaria prophylaxis.
Topics: Antimalarials; Dapsone; Drug Combinations; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Tr | 1981 |
Haemoglobinuria after a single dose treatment with dapsone and pyrimethamine for falciparum malaria in a patient with glucose-6-phosphate dehydrogenase deficiency.
Topics: Child, Preschool; Dapsone; Drug Combinations; Glucosephosphate Dehydrogenase; Glucosephosphate Dehyd | 1981 |
Malaria prophylaxis: guidelines for travellers from Britain. Malaria Reference Laboratory of the Public Health Laboratory Service, London.
Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Culicidae; Dapsone; Doxycycline; | 1995 |
Oxidative activation of proguanil and dapsone acetylation in Thai soldiers.
Topics: Acetylation; Biotransformation; Chromatography, High Pressure Liquid; Dapsone; Humans; Malaria; Mili | 1994 |
A malaria control trial using insecticide-treated bed nets and targeted chemoprophylaxis in a rural area of The Gambia, west Africa. 6. The impact of the interventions on mortality and morbidity from malaria.
Topics: Antimalarials; Child, Preschool; Chloroquine; Dapsone; Drug Combinations; Gambia; Humans; Hygiene; I | 1993 |
A malaria control trial using insecticide-treated bed nets and targeted chemoprophylaxis in a rural area of The Gambia, west Africa. 8. Cost-effectiveness of bed net impregnation alone or combined with chemoprophylaxis in preventing mortality and morbidit
Topics: Antimalarials; Bedding and Linens; Child, Preschool; Cost-Benefit Analysis; Dapsone; Drug Combinatio | 1993 |
Malaria prophylaxis prescribed for travellers from New Zealand.
Topics: Antimalarials; Chloroquine; Dapsone; Drug Combinations; Drug Utilization; Humans; Malaria; New Zeala | 1997 |
[Chemoprophylaxis of malaria in travelers to endemic zones].
Topics: Antimalarials; Chloroquine; Dapsone; Doxycycline; Drug Resistance; Drug Therapy, Combination; Humans | 1998 |
Hypersensitivity syndrome associated with dapsone/pyrimethamine (Maloprim) antimalaria chemoprophylaxis.
Topics: Adult; Antimalarials; Dapsone; Drug Combinations; Drug Hypersensitivity; Glucocorticoids; Humans; Ma | 2002 |
Malaria prophylaxis for visitors to Papua New Guinea.
Topics: Dapsone; Drug Therapy, Combination; Humans; Malaria; New Guinea; Plasmodium falciparum; Pyrimethamin | 1978 |
Falciparum malaria despite chemoprophylaxis.
Topics: Chloroquine; Dapsone; Drug Combinations; Humans; Malaria; Plasmodium falciparum; Pyrimethamine | 1979 |
Malaria in Australia.
Topics: Australia; Chloroquine; Dapsone; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; | 1979 |
Experimental studies on the effect of proguanil and dapsone against chloroquine-resistant Plasmodium berghei (ANKA) in white mice.
Topics: Animals; Chloroquine; Dapsone; Dose-Response Relationship, Drug; Drug Resistance; Drug Therapy, Comb | 1979 |
Treatment and chemoprophylaxis of malaria.
Topics: Aminoquinolines; Antimalarials; Biguanides; Chloroquine; Dapsone; Humans; Malaria; Plasmodium falcip | 1979 |
Determination of plasma concentrations of dapsone, monoacetyl dapsone and pyrimethamine in human subjects dosed with maloprim.
Topics: Adult; Chromatography, High Pressure Liquid; Dapsone; Drug Combinations; Half-Life; Humans; Malaria; | 1979 |
Studies on Azadiracta indica in malaria [proceedings].
Topics: Animals; Dapsone; Malaria; Male; Mice; Plant Extracts; Plants, Medicinal; Plasmodium berghei | 1976 |
[Chemotherapeutically active nitro compounds. 2nd communication: Nitrodiphenyl sulfones (author's transl)].
Topics: Animals; Dapsone; Malaria; Mice; Mice, Inbred Strains; Mycobacterium bovis; Mycobacterium Infections | 1976 |
A comparative study of the efficacy of chloroquine and a combination of dapsone and pyrimethamine in the prophylaxis of malaria in Peninsular Malaysia.
Topics: Adult; Child; Chloroquine; Dapsone; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; M | 1976 |
Evaluating new antimalarial drugs against trophozoite induced Plasmodium cynomolgi malaria in rhesus monkeys.
Topics: Amodiaquine; Animals; Antimalarials; Dapsone; Disease Models, Animal; Dose-Response Relationship, Dr | 1976 |
Breakthrough in fight against malaria.
Topics: Community Health Workers; Dapsone; Drug Combinations; Drug Evaluation; Humans; Infant; Malaria; Pyri | 1975 |
Letter: Prevention of chloroquine-resistant falciparum malaria.
Topics: Chloroquine; Dapsone; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Malaria; Plasmo | 1975 |
An extended field trial of pyrimethamine combined with dapsone in the prophylaxis of malaria.
Topics: Adolescent; Adult; Child; Child, Preschool; Dapsone; Drug Therapy, Combination; Humans; Infant; Mala | 1975 |
Antimalarial activity of some 4-alkylamino 2/3 methoxy-4-aminodiphenyl sulphones.
Topics: Animals; Antimalarials; Dapsone; Malaria; Male; Mice; Molecular Structure; Plasmodium berghei | 1990 |
Anti-sporozoite antibodies and immunity to malaria in a rural Gambian population.
Topics: Age Factors; Animals; Antibodies, Protozoan; Antimalarials; Child; Child, Preschool; Dapsone; Drug C | 1988 |
Malaria in travelers returning from Kenya: failure of self-treatment with pyrimethamine/sulfadoxine.
Topics: Animals; Antimalarials; Dapsone; Drug Combinations; Humans; Kenya; Malaria; Plasmodium falciparum; P | 1989 |
Delay in emergence of mefloquine resistance in Plasmodium berghei by use of drug combinations.
Topics: Animals; Antimalarials; Dapsone; Drug Resistance; Drug Therapy, Combination; Erythromycin; Malaria; | 1989 |
Plasmodium vivax resistance to chloroquine?
Topics: Acute Disease; Animals; Antimalarials; Blood Specimen Collection; Chloroquine; Dapsone; Drug Adminis | 1989 |
Failure of dapsone/pyrimethamine plus chloroquine against falciparum malaria in Papua New Guinea.
Topics: Adult; Animals; Chloroquine; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Malaria; | 1988 |
Compliance with malaria chemoprophylaxis programmes in Zimbabwe.
Topics: Chloroquine; Dapsone; Humans; Malaria; Patient Compliance; Pyrimethamine; Zimbabwe | 1987 |
[Action of nitroquine on tissue schizonts of Plasmodium cynomolgi].
Topics: Animals; Antimalarials; Dapsone; Female; Macaca mulatta; Malaria; Male; Plasmodium; Quinazolines; Re | 1986 |
Malaria chemoprophylaxis with a proguanil-chloroquine-maloprim combination in Papua New Guinea.
Topics: Animals; Antimalarials; Chloroquine; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; | 1988 |
Risk of acute non-specific upper respiratory tract infections in healthy men taking dapsone-pyrimethamine for prophylaxis against malaria.
Topics: Acute Disease; Adolescent; Antimalarials; Dapsone; Drug Combinations; Humans; Immunosuppression Ther | 1988 |
Malaria in north-eastern Botswana.
Topics: Botswana; Dapsone; Drug Therapy, Combination; Humans; Malaria; Pyrimethamine; Sulfadoxine; Sulfanila | 1988 |
Race-linked differences in serum concentrations of dapsone, monoacetyldapsone and pyrimethamine during malaria prophylaxis.
Topics: Adolescent; Adult; Biological Availability; Black People; Dapsone; Drug Combinations; Female; Humans | 1986 |
The effect of dapsone-pyrimethamine on immunoglobulin concentrations in malaria chemoprophylaxis.
Topics: Adolescent; Adult; Antimalarials; Dapsone; Depression, Chemical; Drug Combinations; Humans; Immunogl | 1987 |
The activity of drug combinations against established infections of rodent malaria.
Topics: Animals; Antimalarials; Chloroquine; Dapsone; Drug Therapy, Combination; Malaria; Mice; Plasmodium b | 1987 |
ELISA tests for dapsone and pyrimethamine and their application in a malaria chemoprophylaxis programme.
Topics: Child, Preschool; Dapsone; Drug Combinations; Enzyme-Linked Immunosorbent Assay; Gambia; Humans; Inf | 1986 |
Serious problems with antimalarial drugs.
Topics: Antimalarials; Chloroquine; Dapsone; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Co | 1986 |
Epidemiology of the emergence and spread of drug-resistant falciparum malaria in South-East Asia and Australasia.
Topics: Antimalarials; Asia, Southeastern; Cambodia; Chloroquine; Dapsone; Drug Combinations; Drug Resistanc | 1986 |
Excretion of chloroquine, dapsone and pyrimethamine in human milk.
Topics: Adult; Chloroquine; Dapsone; Drug Combinations; Female; Humans; Malaria; Milk, Human; Pregnancy; Pyr | 1986 |
Malaria prophylaxis.
Topics: Antimalarials; Child; Chloroquine; Dapsone; Drug Combinations; Female; Humans; Malaria; Pregnancy; P | 1986 |
Charge transfer and oxy radicals in antimalarial action. Quinones, dapsone metabolites, metal complexes, iminium ions, and peroxides.
Topics: Aminacrine; Aminoquinolines; Biguanides; Dapsone; Electron Transport; Free Radicals; Imines; Ions; M | 1985 |
Inadequate prophylaxis of malaria with dapsone-pyrimethamine.
Topics: Adolescent; Adult; Antimalarials; Biological Availability; Child; Dapsone; Drug Combinations; Drug R | 1985 |
Malaria prophylaxis for travellers.
Topics: Dapsone; Drug Combinations; Humans; Malaria; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine; | 1985 |
Malaria prophylaxis for Canadian travellers.
Topics: Amodiaquine; Canada; Chloroquine; Dapsone; Doxycycline; Drug Combinations; Drug Resistance, Microbia | 1985 |
Simultaneous estimation of serum concentrations of dapsone, monoacetyldapsone, and pyrimethamine in Chinese men on maloprim for malaria prophylaxis using reversed-phase high performance liquid chromatography.
Topics: Acetylation; Adolescent; Adult; China; Chromatography, High Pressure Liquid; Dapsone; Drug Administr | 1985 |
Susceptibility of Plasmodium falciparum in The Gambia to pyrimethamine, Maloprim and chloroquine.
Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Dapsone; Dose-Response Relationship, Drug; Drug | 1985 |
[Malaria chemoprophylaxis. Resistance problems].
Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Dapsone; Drug Combinations; Drug Resistance, Mi | 1985 |
Haematological safety of long-term malarial prophylaxis with dapsone-pyrimethamine.
Topics: Adolescent; Adult; Age Factors; Antimalarials; Child; Child, Preschool; Dapsone; Drug Combinations; | 1985 |
Maloprim for malaria prophylaxis.
Topics: Antimalarials; Dapsone; Drug Combinations; Humans; Malaria; Pyrimethamine | 1985 |
Drug-resistant malaria.
Topics: Chloroquine; Dapsone; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Primaquine | 1969 |
Prophylaxis of malaria in man using the sulfone DFD with pyrimethamine.
Topics: Chloroquine; Dapsone; Formaldehyde; Humans; Malaria; Male; Plasmodium falciparum; Plasmodium vivax; | 1973 |
Experience with mixed infections of Plasmodium falciparum and vivax.
Topics: Antimalarials; Chloroquine; Dapsone; Humans; Malaria; Military Medicine; Plasmodium falciparum; Plas | 1973 |
Chemotherapeutic results in a multi-drug resistant strain of Plasmodium falciparum malaria from Vietnam.
Topics: Adult; Alanine Transaminase; Anopheles; Antimalarials; Aspartate Aminotransferases; Dapsone; Drug Re | 1974 |
Effects of diaphenylsulphone (dapsone) against Plasmodium vivax of South West Pacific origin.
Topics: Adult; Child; Chloroquine; Culicidae; Dapsone; Drug Resistance, Microbial; Humans; Insect Vectors; M | 1968 |
Kinetic testing of drugs against Mycobacterium leprae in mice. Activity of cephaloridine, rifampin, streptovaricin, vadrine, and viomycin.
Topics: Animals; Antimalarials; Cephaloridine; Dapsone; Diet; Evaluation Studies as Topic; Injections, Subcu | 1971 |
The chemoprophylactic use of diformyl diaminodiphenyl sulfone (DFD) in falciparum malaria.
Topics: Adult; Anopheles; Antimalarials; Blood Cell Count; Chloroquine; Dapsone; Drug Resistance, Microbial; | 1972 |
Quinine infusion for recrudescences of falciparum malaria in Vietnam: a controlled study.
Topics: Dapsone; Humans; Infusions, Parenteral; Malaria; Plasmodium falciparum; Pyrimethamine; Quinine; Recu | 1972 |
DDS: mechanisms of action and structure-activity relationships.
Topics: Adenosine; Animals; Biological Transport; Cell Membrane Permeability; Dapsone; Leprosy; Malaria; Pla | 1972 |
Responsibility for failure of sulphonamides in falciparum malaria; host or parasite?
Topics: Dapsone; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Sulfonamides | 1972 |
Recrudescent falciparum malaria in Vietnam.
Topics: Adult; Black People; Dapsone; Fever; Follow-Up Studies; Humans; Malaria; Male; Military Medicine; Pl | 1973 |
Malaria in the Australian army in South Vietnam: successful use of a proguanil-dapsone combination for chemoprophylaxis of chloroquine-resistant falciparum malaria.
Topics: Australia; Chloroquine; Dapsone; Disease Outbreaks; Drug Resistance, Microbial; Humans; Malaria; Mil | 1973 |
Letter: Malaria in the Australian army in South Vietnam.
Topics: Australia; Dapsone; Humans; Malaria; Military Medicine; Plasmodium falciparum; Plasmodium vivax; Pro | 1973 |
Letter: Malaria in the Australian army in South Vietnam.
Topics: Dapsone; Disease Outbreaks; Drug Resistance, Microbial; Humans; Malaria; Male; Military Medicine; Pl | 1973 |
The suppression of Plasmodium falciparum and Plasmodium vivax parasitaemias by a dapsone-pyrimethamine combination.
Topics: Adolescent; Adult; Child; Chloroquine; Dapsone; Drug Combinations; Female; Hematocrit; Humans; Malar | 1973 |
Chloroquine-resistant Falciparum malaria acquired in Vietnam.
Topics: Acute Kidney Injury; Adolescent; Adult; Blood Cell Count; Chloroquine; Dapsone; Drug Resistance, Mic | 1973 |
Malaria in New York City. IV. 1960-1971.
Topics: Adolescent; Adult; Africa, Western; Age Factors; Amodiaquine; Child; Child, Preschool; Chloroquine; | 1974 |
A comparison between the quinine and chloroquine regimens for falciparum malaria in Vietnam.
Topics: Administration, Oral; Chloroquine; Dapsone; Humans; Injections, Intravenous; Malaria; Male; Military | 1974 |
Chemoprophylaxis of malaria for travelers.
Topics: Africa; Antimalarials; Asia; Central America; Chloroquine; Dapsone; Drug Resistance, Microbial; Drug | 1974 |
Considerations on the use of sulphones and sulphonamides with a pyrimidine derivative.
Topics: Adult; Amodiaquine; Child; Dapsone; Drug Combinations; Drug Resistance, Microbial; Humans; Malaria; | 1974 |
Some pharmacological aspects of antimalarial drugs.
Topics: Antimalarials; Chloroquine; Dapsone; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falcipa | 1974 |
Treatment of drug-resistant malaria in man.
Topics: Africa; Antimalarials; Asia; Central America; Dapsone; Drug Resistance; Drug Therapy, Combination; H | 1974 |
Letter: An acute attack of quartan malaria in a leprosy patient being treated with diaminodiphenylsulphone.
Topics: Acute Disease; Adult; Dapsone; Humans; Leprosy; Malaria; Malaysia; Male; Plasmodium malariae | 1974 |
Reduced pressure potentiation of the side effects of the antimalarial, Dapsone.
Topics: Aerospace Medicine; Altitude; Anemia; Animals; Asia, Southeastern; Dapsone; Erythrocyte Count; Hyper | 1967 |
Antimalarial effects of sulphormethoxine, diaphenylsulphone and separate combinations of these with pyrimethamine: a review of preliminary investigations carried out in Tanzania.
Topics: Adolescent; Adult; Antimalarials; Child; Chloroquine; Dapsone; Drug Hypersensitivity; Drug Resistanc | 1968 |
Chloroquine-pyrimethamine-sulfisoxazole therapy of Plasmodium falciparum malaria. An alternative to quinine.
Topics: Chloroquine; Dapsone; Drug Resistance, Microbial; Fever; Humans; Malaria; Male; Military Medicine; P | 1969 |
Studies on the chemotherapy of malaria. II. Pyrimethamine resistance in The Gambia.
Topics: Carrier State; Child; Child, Preschool; Dapsone; Drug Resistance, Microbial; Erythrocytes; Female; G | 1970 |
Curative and suppressive treatment of P. falciparum malaria with oral and parenteral Fansidar.
Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Child; Child, Preschool; Chloroquine; Dapson | 1971 |
Chloroquine-resistant Plasmodium falciparum: protective and hemolytic effects of 4,4'-diaminodiphenylsulfone (DDS) administered daily together with weekly chloroquine and primaquine.
Topics: Adult; Black or African American; Chloroquine; Dapsone; Hemolysis; Humans; Malaria; Male; Plasmodium | 1967 |
Prophylaxis of malaria in man using the sulfones DFD and DDS alone and with chloroquine.
Topics: Adult; Chloroquine; Dapsone; Humans; Malaria; Male; Sulfones | 1971 |
The effects of diaphenylsulfone (DDS) against chloroquine-resistant Plasmodium falciparum.
Topics: Adult; Aminobenzoates; Dapsone; Drug Resistance, Microbial; Humans; Malaria; Male; Plasmodium falcip | 1966 |
Supplemental sulfone (dapsone) therapy. Use in treatment of chloroquine-resistant falciparum malaria.
Topics: Adolescent; Adult; Anemia, Hemolytic; Chemical Phenomena; Chemistry, Physical; Dapsone; Humans; Mala | 1967 |
Management of chloroquine resistant falciparum malaria.
Topics: Adult; Brain Diseases; Chloroquine; Dapsone; Dexamethasone; Drug Resistance, Microbial; Edema; Human | 1967 |
Agranulocytosis probably due to dapsone in an infantry soldier.
Topics: Adult; Agranulocytosis; Australia; Dapsone; Humans; Malaria; Male; Military Personnel; Pseudomonas I | 1970 |
Suggested new mechanisms of antimalarial action for DDS involving inhibition of glucose utilization by the intraerythrocytic parasite.
Topics: Aminobenzoates; Animals; Autoanalysis; Biological Transport; Cell Membrane; Dapsone; Erythrocytes; F | 1970 |
Agranulocytosis due to dapsone.
Topics: Adult; Agranulocytosis; Dapsone; Humans; Malaria; Male; Military Medicine; Time Factors; Tropical Me | 1970 |
The chemotherapy of rodent malaria. IX. Causal prophylaxis. I. A method for demonstrating drug action on exo-erythrocytic stages.
Topics: Animals; Antimalarials; Chloroquine; Dapsone; Malaria; Male; Mice; Plasmodium; Primaquine; Proguanil | 1970 |
Potential antimalarial agents derivatives of 4,4'- diaminodiphenylsulfone.
Topics: Animals; Antimalarials; Chemical Phenomena; Chemistry; Dapsone; Injections; Injections, Intraperiton | 1971 |
Partial reversal of the in vivo antimalarial activity of DDS against Plasmodium berghei by induced hyperglycemia.
Topics: Administration, Oral; Alloxan; Animals; Antimalarials; Blood Glucose; Dapsone; Erythrocytes; Glucose | 1971 |
Resistant malaria.
Topics: Child; Dapsone; Drug Resistance, Microbial; Drug Synergism; Humans; Malaria; Pyrimethamine; Pyrimidi | 1971 |
Medical problems from Vietnam.
Topics: Dapsone; Humans; Malaria; Military Medicine; Pyrimethamine; Quinine; Vietnam | 1968 |
Methemoglobinemia provoked by malarial chemoprophylaxis in Vietnam.
Topics: Antimalarials; Chloroquine; Cyanosis; Dapsone; Diseases in Twins; Erythrocytes; Female; Hematocrit; | 1968 |
Characteristics and cross-resistance patterns of chloroquine-resistant Plasmodium berghei infections in mice.
Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Dapsone; Drug Resistance, Microbial; Female; Hemat | 1968 |
Treatment of acute falciparum malaria with diaphenylsulfone in North-East Tanzania.
Topics: Africa, Eastern; Dapsone; Humans; Malaria | 1965 |
Drug resistance in Plasmodium berghei Vincke and Lips, 1948. II. Triazine resistance.
Topics: Animals; Dapsone; In Vitro Techniques; Malaria; Mice; Plasmodium; Primaquine; Proguanil; Pyrimethami | 1965 |
Drug resistance in Plasmodium berghei Vincke and Lips, 1948. I. Chloroquine resistance.
Topics: Amodiaquine; Animals; Chloroquine; Dapsone; Malaria; Mice; Plasmodium; Primaquine; Proguanil; Pyrime | 1965 |
Drug resistance in Plasmodium berghei Vincke and Lips, 1948. 3. Multiple drug resistance.
Topics: Animals; Antimalarials; Dapsone; In Vitro Techniques; Malaria; Mice; Plasmodium; Quinacrine; Sulfadi | 1965 |