Page last updated: 2024-10-25

dapsone and Malaria

dapsone has been researched along with Malaria in 180 studies

Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.

Research Excerpts

ExcerptRelevanceReference
"Chlorproguanil-dapsone (CD) has been linked to hemolysis in symptomatic glucose-6-phosphate dehydrogenase deficient (G6PDd) children."9.20Risks of Hemolysis in Glucose-6-Phosphate Dehydrogenase Deficient Infants Exposed to Chlorproguanil-Dapsone, Mefloquine and Sulfadoxine-Pyrimethamine as Part of Intermittent Presumptive Treatment of Malaria in Infants. ( Alifrangis, M; Baraka, V; Carneiro, I; Chandramohan, D; Gesase, S; Gosling, R; Hashim, R; Ishengoma, D; Mosha, J; Poirot, E; Vittinghoff, E, 2015)
"Chlorproguanil-dapsone (Lapdap), developed as a low-cost antimalarial, was withdrawn in 2008 after concerns about safety in G6PD deficient patients."9.15Randomized trial of safety and effectiveness of chlorproguanil-dapsone and lumefantrine-artemether for uncomplicated malaria in children in the Gambia. ( Adiamoh, M; Bisseye, C; Cheung, YB; Conway, D; Diatta, M; Dunyo, S; Janha, R; Milligan, P; Njie, F; Nwakanma, D; Sesay, S; Sirugo, G; Sisay Joof, F; Snell, P; Temple, B; Walton, R, 2011)
"Pregnant women with non-severe, slide proven, falciparum malaria were randomised to one of 4 regimes: sulfadoxine-pyrimethamine [SP]; chlorproguanil-dapsone [CD]; SP+amodiaquine [SP+AQ] or amodiaquine+artesunate [AQ+AS]."9.14Randomized trial of artesunate+amodiaquine, sulfadoxine-pyrimethamine+amodiaquine, chlorproguanal-dapsone and SP for malaria in pregnancy in Tanzania. ( Briceño, M; Drakeley, C; Greenwood, BM; Mutabingwa, TK; Muze, K; Ord, R; Whitty, CJ, 2009)
"Sulphadoxine-pyrimethamine (SP) is the only single dose therapy for uncomplicated malaria, but there is widespread resistance."9.14Measurement of adherence, drug concentrations and the effectiveness of artemether-lumefantrine, chlorproguanil-dapsone or sulphadoxine-pyrimethamine in the treatment of uncomplicated malaria in Malawi. ( Bell, DJ; Chimpeni, P; Hughes, DA; Kayange, N; Lalloo, DG; Molyneux, ME; Montgomery, J; Mukaka, M; Ward, SA; Winstanley, PA; Wootton, D, 2009)
"Artesunate+amodiaquine (AS+AQ) and artemether-lumefantrine (AL) are now the most frequently recommended first line treatments for uncomplicated malaria in Africa."9.13An open label, randomised trial of artesunate+amodiaquine, artesunate+chlorproguanil-dapsone and artemether-lumefantrine for the treatment of uncomplicated malaria. ( Adjuik, M; Amenga-Etego, S; Asante, KP; Chandramohan, D; Dosoo, DK; Greenwood, B; Gyapong, J; Owusu, R; Owusu-Agyei, S, 2008)
"Two field trials to detect chloroquine-resistant malaria were conducted according to WHO recommendations in a malaria free area near Rangoon."9.04Chloroquine-resistant malaria in Burma. ( Hlaing, N; Htun Nyun, R; Kyi, KK; Myint, T; Tin, F; U, T, 1975)
"Randomized and quasi-randomized controlled trials comparing chlorproguanil-dapsone to other antimalarial drugs."8.82Chlorproguanil-dapsone for treating uncomplicated malaria. ( Bukirwa, H; Critchley, J; Garner, P, 2004)
"Resistance is readily produced in rodent malaria using the single-dose, '2%-relapse technique' (2%RT) against the individual compounds chlorproguanil (CPG), chlorcycloguanil (CCG), cycloguanil, dapsone (DDS) and artesunate (ASN)."7.73The chemotherapy of rodent malaria. LXIII. Drug combinations to impede the selection of drug resistance, part 6: the potential value of chlorproguanil and dapsone in combination, and with the addition of artesunate. ( Peters, W; Robinson, BL; Stewart, LB, 2005)
"The relative risks of non-specific upper respiratory tract infections were studied in two well matched groups of military recruits to see whether dapsone-pyrimethamine (Maloprim) given as antimalarial prophylaxis was associated with immunosuppression."7.67Risk of acute non-specific upper respiratory tract infections in healthy men taking dapsone-pyrimethamine for prophylaxis against malaria. ( Lau, EY; Lee, PS, 1988)
"A mechanism of action is proposed that encompasses almost all of the main categories of antimalarial agents: quinones and precursors, dapsone metabolites, metal complexes of thiosemicarbazones and biguanides, iminium-type ions from acridines and quinolines, and peroxides."7.67Charge transfer and oxy radicals in antimalarial action. Quinones, dapsone metabolites, metal complexes, iminium ions, and peroxides. ( Ames, JR; Klayman, DL; Kovacic, P; Ryan, MD, 1985)
"A reversed-phase high performance liquid chromatography method was developed to simultaneously estimate serum concentrations of dapsone (DDS), monoacetyldapsone (MADDS), and pyrimethamine (PYR) in 34 young adult Chinese men after they had taken the sixth weekly dose of Maloprim for malaria prophylaxis."7.67Simultaneous estimation of serum concentrations of dapsone, monoacetyldapsone, and pyrimethamine in Chinese men on maloprim for malaria prophylaxis using reversed-phase high performance liquid chromatography. ( Lee, HS; Lee, PS; Ti, TY; Yap, CL, 1985)
"The duration of protection from blood-stage malarial challenge following single injections of pyrimethamine pamoate was assessed in mice and monkeys."7.67Long-acting, repository antimalarial agents. Duration of protection in mice and monkeys following administration of pyrimethamine pamoate. ( Jacobs, RL; Steinkampf, RW; Werbel, LM; Worth, DF, 1984)
"There are no published haematological data on the long-term (more than one year) use of dapsone-pyrimethamine (Maloprim, Folaprim; one tablet a week) for malarial prophylaxis."7.67Haematological safety of long-term malarial prophylaxis with dapsone-pyrimethamine. ( Cook, IF; Kish, MY, 1985)
"Proguanil 200mg daily and chloroquine base 300mg weekly along with maloprim 1 tablet weekly was used as malaria chemoprophylaxis for 140 Hong Kong based soliders on a seven-week jungle exercise in a holoendemic malarial area of Papua New Guinea."7.67Malaria chemoprophylaxis with a proguanil-chloroquine-maloprim combination in Papua New Guinea. ( Heap, BJ, 1988)
"Malaria is a leading cause of mortality, particularly in sub-Saharan African children."6.77Glucose-6-phosphate dehydrogenase deficiency, chlorproguanil-dapsone with artesunate and post-treatment haemolysis in African children treated for uncomplicated malaria. ( Bassat, Q; D' Alessandro, U; Daniel, A; Forret, P; González, R; Machevo, S; Nabasumba, C; Piola, P; Robert, A; Talisuna, A; Turyakira, E; Van Geertruyden, JP; van Loen, H; Van Malderen, C; Van Overmeir, C; Yeka, A, 2012)
"Pyrimethamine alone was ineffective."6.64Single-dose therapy of Falciparum malaria using pyrimethamine in combination with diformyldapsone or sulfadoxine. ( Doberstyn, EB; Hall, AP; Sonkon, P; Vetvutanapibul, K, 1976)
"001) serum concentrations of PYR were found in Papua New Guineans than in Caucasians at both sampling times, an observation which may reflect differences in the bioavailability of PYR between the two racial groups."5.27Race-linked differences in serum concentrations of dapsone, monoacetyldapsone and pyrimethamine during malaria prophylaxis. ( Cochrane, JP; Cook, IF; Edstein, MD, 1986)
"Chlorproguanil-dapsone (CD) has been linked to hemolysis in symptomatic glucose-6-phosphate dehydrogenase deficient (G6PDd) children."5.20Risks of Hemolysis in Glucose-6-Phosphate Dehydrogenase Deficient Infants Exposed to Chlorproguanil-Dapsone, Mefloquine and Sulfadoxine-Pyrimethamine as Part of Intermittent Presumptive Treatment of Malaria in Infants. ( Alifrangis, M; Baraka, V; Carneiro, I; Chandramohan, D; Gesase, S; Gosling, R; Hashim, R; Ishengoma, D; Mosha, J; Poirot, E; Vittinghoff, E, 2015)
"Chlorproguanil-dapsone (Lapdap), developed as a low-cost antimalarial, was withdrawn in 2008 after concerns about safety in G6PD deficient patients."5.15Randomized trial of safety and effectiveness of chlorproguanil-dapsone and lumefantrine-artemether for uncomplicated malaria in children in the Gambia. ( Adiamoh, M; Bisseye, C; Cheung, YB; Conway, D; Diatta, M; Dunyo, S; Janha, R; Milligan, P; Njie, F; Nwakanma, D; Sesay, S; Sirugo, G; Sisay Joof, F; Snell, P; Temple, B; Walton, R, 2011)
"Intermittent preventive treatment in infants (IPTi) with sulphadoxine-pyrimethamine (SP) for the prevention of malaria has shown promising results in six trials."5.14Intermittent preventive treatment in infants for the prevention of malaria in rural Western kenya: a randomized, double-blind placebo-controlled trial. ( Hamel, MJ; Kariuki, S; Lindblade, K; Newman, RD; Odhiambo, FO; Otieno, P; Peterson, E; Slutsker, L; ter Kuile, FO; Vulule, J; Williamson, J, 2010)
"Pregnant women with non-severe, slide proven, falciparum malaria were randomised to one of 4 regimes: sulfadoxine-pyrimethamine [SP]; chlorproguanil-dapsone [CD]; SP+amodiaquine [SP+AQ] or amodiaquine+artesunate [AQ+AS]."5.14Randomized trial of artesunate+amodiaquine, sulfadoxine-pyrimethamine+amodiaquine, chlorproguanal-dapsone and SP for malaria in pregnancy in Tanzania. ( Briceño, M; Drakeley, C; Greenwood, BM; Mutabingwa, TK; Muze, K; Ord, R; Whitty, CJ, 2009)
"Sulphadoxine-pyrimethamine (SP) is the only single dose therapy for uncomplicated malaria, but there is widespread resistance."5.14Measurement of adherence, drug concentrations and the effectiveness of artemether-lumefantrine, chlorproguanil-dapsone or sulphadoxine-pyrimethamine in the treatment of uncomplicated malaria in Malawi. ( Bell, DJ; Chimpeni, P; Hughes, DA; Kayange, N; Lalloo, DG; Molyneux, ME; Montgomery, J; Mukaka, M; Ward, SA; Winstanley, PA; Wootton, D, 2009)
"Artesunate+amodiaquine (AS+AQ) and artemether-lumefantrine (AL) are now the most frequently recommended first line treatments for uncomplicated malaria in Africa."5.13An open label, randomised trial of artesunate+amodiaquine, artesunate+chlorproguanil-dapsone and artemether-lumefantrine for the treatment of uncomplicated malaria. ( Adjuik, M; Amenga-Etego, S; Asante, KP; Chandramohan, D; Dosoo, DK; Greenwood, B; Gyapong, J; Owusu, R; Owusu-Agyei, S, 2008)
"A cohort of 48 Gambian children was protected against malaria by fortnightly administration of Maloprim (pyrimethamine and dapsone) for 2 years between their 3 and 5 birthdays."5.06Immunity to malaria in young Gambian children after a two-year period of chemoprophylaxis. ( Byass, P; Greenwood, BM; Menon, A; Otoo, LN; Snow, RW, 1988)
"Two drug strategies for the control of malaria in children aged 3-59 months have been compared in a rural area of The Gambia--treatment of presumptive episodes of clinical malaria with chloroquine by village health workers, and treatment combined with fortnightly chemoprophylaxis with 'Maloprim' (pyrimethamine/dapsone) which was also given by village health workers."5.06Comparison of two strategies for control of malaria within a primary health care programme in the Gambia. ( Bradley, AK; Byass, P; Greenwood, AM; Greenwood, BM; Hayes, RJ; N'Jie, AB; Snow, RW, 1988)
"A battalion of Royal Thai Marine militia was assigned to take either 50 mg or 100 mg of doxycycline daily or pyrimethamine/dapsone weekly for malaria prophylaxis on the Thai-Kampuchean border for a 17 week period."5.06Malaria prophylaxis with doxycycline in soldiers deployed to the Thai-Kampuchean border. ( Karwacki, JJ; Phintuyothin, P; Pilungkasa, S; Shanks, D; Singharaj, P; Suriyamongkol, V; Wasuwat, P; Watanasook, C, 1989)
"We have reviewed a malaria chemoprophylaxis programme in which Maloprim (pyrimethamine and dapsone) has been administered fortnightly by village health workers (VHWs) to approximately 1500 children each year aged 6-59 months resident in 15 primary health care villages in a rural area of The Gambia over 5 years."5.06Compliance with malaria chemoprophylaxis over a five-year period among children in a rural area of The Gambia. ( Allen, SJ; Greenwood, BM; Menon, A; Snow, RW, 1990)
"Two field trials to detect chloroquine-resistant malaria were conducted according to WHO recommendations in a malaria free area near Rangoon."5.04Chloroquine-resistant malaria in Burma. ( Hlaing, N; Htun Nyun, R; Kyi, KK; Myint, T; Tin, F; U, T, 1975)
"In an area of Thailand where chloroquine-resistant falciparum malaria is known to exist, a chemosuppressive field trial was undertaken to test the efficacy of the preparation diformyldapsone (DFD) combined with pyrimethamine (Py) in suppressing falciparum and vivax parasitemias."5.04Chemosuppressive field trials in Thailand. II. The suppression of Plasmodium falciparum and Plasmodium vivax parasitemias by a diformyldapsone-pyrimethamine combination. ( Castaneda, BF; Pearlman, EJ; Thiemanun, W, 1975)
"From 1936 until 1996, the drug dapsone treated a diverse array of diseases, including tuberculosis, leprosy, malaria, and AIDS-related pneumonia."4.87A short history of dapsone, or an alternative model of drug development. ( Barr, J, 2011)
"Randomized and quasi-randomized controlled trials comparing chlorproguanil-dapsone to other antimalarial drugs."4.82Chlorproguanil-dapsone for treating uncomplicated malaria. ( Bukirwa, H; Critchley, J; Garner, P, 2004)
"From 1936 until 1996, the drug dapsone treated a diverse array of diseases, including tuberculosis, leprosy, malaria, and AIDS-related pneumonia."3.77A short history of dapsone, or an alternative model of drug development. ( Barr, J, 2011)
"Resistance is readily produced in rodent malaria using the single-dose, '2%-relapse technique' (2%RT) against the individual compounds chlorproguanil (CPG), chlorcycloguanil (CCG), cycloguanil, dapsone (DDS) and artesunate (ASN)."3.73The chemotherapy of rodent malaria. LXIII. Drug combinations to impede the selection of drug resistance, part 6: the potential value of chlorproguanil and dapsone in combination, and with the addition of artesunate. ( Peters, W; Robinson, BL; Stewart, LB, 2005)
" In this study the plasma metabolic ratios of proguanil and dapsone to their principal metabolites cycloguanil and monoacetyldapsone were determined in Thai soldiers receiving antifolate drug combinations for malaria prophylaxis."3.69Oxidative activation of proguanil and dapsone acetylation in Thai soldiers. ( Edstein, MD; Rieckmann, KH; Shanks, GD; Teja-Isavadharm, P; Webster, HK, 1994)
"Two soldiers continued weekly prophylaxis with 300 mg chloroquine base on their return to Australia from Papua New Guinea but were not protected against Plasmodium vivax malaria."3.67Plasmodium vivax resistance to chloroquine? ( Davis, DR; Hutton, DC; Rieckmann, KH, 1989)
"The relative risks of non-specific upper respiratory tract infections were studied in two well matched groups of military recruits to see whether dapsone-pyrimethamine (Maloprim) given as antimalarial prophylaxis was associated with immunosuppression."3.67Risk of acute non-specific upper respiratory tract infections in healthy men taking dapsone-pyrimethamine for prophylaxis against malaria. ( Lau, EY; Lee, PS, 1988)
"The duration of protection from blood-stage malarial challenge following single injections of pyrimethamine pamoate was assessed in mice and monkeys."3.67Long-acting, repository antimalarial agents. Duration of protection in mice and monkeys following administration of pyrimethamine pamoate. ( Jacobs, RL; Steinkampf, RW; Werbel, LM; Worth, DF, 1984)
"Proguanil 200mg daily and chloroquine base 300mg weekly along with maloprim 1 tablet weekly was used as malaria chemoprophylaxis for 140 Hong Kong based soliders on a seven-week jungle exercise in a holoendemic malarial area of Papua New Guinea."3.67Malaria chemoprophylaxis with a proguanil-chloroquine-maloprim combination in Papua New Guinea. ( Heap, BJ, 1988)
"A reversed-phase high performance liquid chromatography method was developed to simultaneously estimate serum concentrations of dapsone (DDS), monoacetyldapsone (MADDS), and pyrimethamine (PYR) in 34 young adult Chinese men after they had taken the sixth weekly dose of Maloprim for malaria prophylaxis."3.67Simultaneous estimation of serum concentrations of dapsone, monoacetyldapsone, and pyrimethamine in Chinese men on maloprim for malaria prophylaxis using reversed-phase high performance liquid chromatography. ( Lee, HS; Lee, PS; Ti, TY; Yap, CL, 1985)
"Several drugs are used for malaria chemoprophylaxis: 4 amino-quinolines, antifolics, combinations of sulfonamides and antifolics, and new anti-malarial agents, including mefloquine."3.67[Malaria chemoprophylaxis. Resistance problems]. ( Danis, M; Gentilini, M, 1985)
"There are no published haematological data on the long-term (more than one year) use of dapsone-pyrimethamine (Maloprim, Folaprim; one tablet a week) for malarial prophylaxis."3.67Haematological safety of long-term malarial prophylaxis with dapsone-pyrimethamine. ( Cook, IF; Kish, MY, 1985)
"A mechanism of action is proposed that encompasses almost all of the main categories of antimalarial agents: quinones and precursors, dapsone metabolites, metal complexes of thiosemicarbazones and biguanides, iminium-type ions from acridines and quinolines, and peroxides."3.67Charge transfer and oxy radicals in antimalarial action. Quinones, dapsone metabolites, metal complexes, iminium ions, and peroxides. ( Ames, JR; Klayman, DL; Kovacic, P; Ryan, MD, 1985)
"As part of the search for new antimalarial drugs, a screening program was developed using sensitive and chlorguanide triazine (CGT, cycloguanil) resistant strains of the folate-requiring bacteria, Streptococcus faecium durans, Lactobacillus casei, and Pediococcus cerevisiae."3.65Antifolate studies. Activities of 40 potential antimalarial compounds against sensitive and chlorguanide triazine resistant strains of folate-requiring bacteria and Escherichia coli. ( Genther, CS; Smith, CS, 1977)
"Malaria is a leading cause of mortality, particularly in sub-Saharan African children."2.77Glucose-6-phosphate dehydrogenase deficiency, chlorproguanil-dapsone with artesunate and post-treatment haemolysis in African children treated for uncomplicated malaria. ( Bassat, Q; D' Alessandro, U; Daniel, A; Forret, P; González, R; Machevo, S; Nabasumba, C; Piola, P; Robert, A; Talisuna, A; Turyakira, E; Van Geertruyden, JP; van Loen, H; Van Malderen, C; Van Overmeir, C; Yeka, A, 2012)
"Pyrimethamine alone was ineffective."2.64Single-dose therapy of Falciparum malaria using pyrimethamine in combination with diformyldapsone or sulfadoxine. ( Doberstyn, EB; Hall, AP; Sonkon, P; Vetvutanapibul, K, 1976)
"Prophylaxis and intermittent treatment with antimalarial drugs reduce clinical malaria and severe anaemia in preschool children."2.43Chemoprophylaxis and intermittent treatment for preventing malaria in children. ( Garner, P; Meremikwu, MM; Omari, AA, 2005)
"Although malaria has been widely eradicated in many parts of the world, the global number of cases continues to rise."2.42New antimalarial drugs. ( Jomaa, H; Ortmann, R; Schlitzer, M; Wiesner, J, 2003)
" Safe and effective drugs, capable of being administered as a single-dose or short-course treatment, are urgently needed to control the adaptable malaria parasite."2.36Falciparum malaria: the urgent need for safe and effective drugs. ( Rieckmann, KH, 1983)
"Early childhood malaria is often fatal, but its impact on the development and education of survivors has not received much attention."1.40Early childhood malaria prevention and children's patterns of school leaving in the Gambia. ( Jukes, MC; Zuilkowski, SS, 2014)
") was tested alone, or in a double and triple combination with a fixed oral dose of 1."1.35Plasmodium berghei: efficacy of 5-fluoroorotate in combination with commonly used antimalarial drugs in a mouse model. ( Ishih, A; Kano, S; Kino, H; Muregi, FW, 2009)
"Chloroquine plus Maloprim was used significantly more by general practitioners in older age groups, ie 45 years and over (p < 0."1.30Malaria prophylaxis prescribed for travellers from New Zealand. ( Heydon, JL; Leggat, PA; Menon, A, 1997)
"In The Gambia, insecticide impregnation of bed nets, used alone or combined with Maloprim, reduced morbidity and mortality from malaria amongst children between one and 4 years of age."1.29A malaria control trial using insecticide-treated bed nets and targeted chemoprophylaxis in a rural area of The Gambia, west Africa. 8. Cost-effectiveness of bed net impregnation alone or combined with chemoprophylaxis in preventing mortality and morbidit ( Aikins, M; Alonso, PL; Armstrong Schellenberg, JR; Greenwood, BM; Mills, A; Picard, J, 1993)
"Blood induced Plasmodium berghei infection in Swiss mice was exposed during successive passages to melfloquine alone or melfoquine in combination with dapsone or primaquine or erythromycin, and the level of resistance to melfoquine in four sub-lines was compared at ED90 level."1.28Delay in emergence of mefloquine resistance in Plasmodium berghei by use of drug combinations. ( Dutta, GP; Puri, SK, 1989)
"001) serum concentrations of PYR were found in Papua New Guineans than in Caucasians at both sampling times, an observation which may reflect differences in the bioavailability of PYR between the two racial groups."1.27Race-linked differences in serum concentrations of dapsone, monoacetyldapsone and pyrimethamine during malaria prophylaxis. ( Cochrane, JP; Cook, IF; Edstein, MD, 1986)
"A high-performance liquid chromatographic method was developed to enable dapsone, monoacetyl dapsone and pyrimethamine to be measured simultaneously in plasma samples from volunteers in England and Malaysia who had been dosed with Maloprim."1.26Determination of plasma concentrations of dapsone, monoacetyl dapsone and pyrimethamine in human subjects dosed with maloprim. ( Jones, CR; Ovenell, SM, 1979)

Research

Studies (180)

TimeframeStudies, this research(%)All Research%
pre-1990145 (80.56)18.7374
1990's14 (7.78)18.2507
2000's11 (6.11)29.6817
2010's9 (5.00)24.3611
2020's1 (0.56)2.80

Authors

AuthorsStudies
Genther, CS1
Smith, CS1
Tibon, NS1
Ng, CH1
Cheong, SL1
Zuilkowski, SS1
Jukes, MC1
Barr, J2
Poirot, E1
Vittinghoff, E1
Ishengoma, D1
Alifrangis, M1
Carneiro, I2
Hashim, R2
Baraka, V1
Mosha, J1
Gesase, S2
Chandramohan, D3
Gosling, R2
Owusu-Agyei, S1
Asante, KP1
Owusu, R1
Adjuik, M1
Amenga-Etego, S1
Dosoo, DK1
Gyapong, J1
Greenwood, B3
Muregi, FW1
Kano, S1
Kino, H1
Ishih, A1
Mutabingwa, TK1
Muze, K1
Ord, R1
Briceño, M1
Greenwood, BM9
Drakeley, C1
Whitty, CJ1
Bell, DJ1
Wootton, D1
Mukaka, M1
Montgomery, J1
Kayange, N1
Chimpeni, P1
Hughes, DA1
Molyneux, ME1
Ward, SA1
Winstanley, PA1
Lalloo, DG1
Cairns, M1
Mosha, JF1
Kaur, H1
Lemnge, M1
Mosha, FW1
Odhiambo, FO1
Hamel, MJ1
Williamson, J1
Lindblade, K1
ter Kuile, FO1
Peterson, E1
Otieno, P1
Kariuki, S1
Vulule, J1
Slutsker, L1
Newman, RD1
Dunyo, S1
Sirugo, G1
Sesay, S1
Bisseye, C1
Njie, F1
Adiamoh, M1
Nwakanma, D1
Diatta, M1
Janha, R1
Sisay Joof, F1
Temple, B1
Snell, P1
Conway, D1
Walton, R1
Cheung, YB1
Milligan, P1
Van Malderen, C1
Van Geertruyden, JP1
Machevo, S1
González, R1
Bassat, Q1
Talisuna, A1
Yeka, A1
Nabasumba, C1
Piola, P1
Daniel, A1
Turyakira, E1
Forret, P1
Van Overmeir, C1
van Loen, H1
Robert, A1
D' Alessandro, U1
Donegan, S1
Williamson, P1
D'Alessandro, U1
Tudur Smith, C1
RAMAKRISHNAN, SP1
BASU, PC2
SINGH, H1
SINGH, N2
SINGH, NN1
THOMPSON, PE1
OLSZEWSKI, B1
WAITZ, JA1
Wiesner, J1
Ortmann, R1
Jomaa, H1
Schlitzer, M1
Bukirwa, H1
Garner, P2
Critchley, J1
Peters, W9
Stewart, LB1
Robinson, BL1
Meremikwu, MM1
Omari, AA1
Edwards, G1
Biagini, GA1
Nyunt, MM1
Plowe, CV1
Sheehy, TW2
Reba, RC2
Clyde, DF8
Most, H1
Herman, R1
Schoenfeld, C1
McLarty, DG1
Webber, RH1
Jaatinen, M1
Kihamia, CH1
Murru, M1
Kumano, M1
Aubert, B1
Magnuson, LW1
Werbel, LM1
Jacobs, RL1
Steinkampf, RW1
Worth, DF1
Rieckmann, KH7
Ponnampalam, JT3
Richards, PN1
Spracklen, FH2
Biddulph, J2
Schmidt, LH1
Rossan, RN1
Ikram, RB1
Faoagali, JL1
Paltridge, GP1
Rée, GH1
Friman, G1
Nyström-Rosander, C1
Jonsell, G1
Björkman, A1
Lekås, G1
Svendsrup, B1
Vergara, RV1
Gelfand, M1
Froese, EH1
Das, S1
Barkakaty, BN1
Talukdar, A1
Roy, RG1
Pattanayak, S1
Woodruff, AW1
Thomson, NP1
Cooke, RA1
Shannon, J1
Fox, JS1
Bradley, DJ1
Warhurst, DC1
Menendez, C1
Todd, J1
Alonso, PL4
Lulat, S1
Francis, N1
Edstein, MD4
Shanks, GD2
Teja-Isavadharm, P1
Webster, HK1
Lindsay, SW2
Armstrong Schellenberg, JR2
Keita, K1
Gomez, P1
Shenton, FC3
Hill, AG2
David, PH2
Fegan, G2
Cham, K1
Picard, J1
Aikins, M1
Mills, A1
Petersen, E1
Marbiah, NT1
Magbiti, E1
Lines, JD1
Maude, GH1
Høgh, B1
Curtis, C1
Bradley, D1
Leggat, PA1
Heydon, JL1
Menon, A3
de Górgolas Hernández-Mora, M1
Blanco García, A1
Martín Torres, MP1
Fernández Guerrero, ML1
Griffin, JP1
Thong, BY1
Leong, KP1
Chng, HH1
Htun Nyun, R1
Hlaing, N1
Tin, F1
U, T1
Myint, T1
Kyi, KK1
Pearlman, EJ5
Lampe, RM1
Thiemanun, W3
Kennedy, RS1
Black, RH4
Bentley, SJ1
Ray, AP1
Parkinson, AD1
Spicer, AJ1
Jones, CR1
Ovenell, SM1
Doberstyn, EB1
Hall, AP6
Vetvutanapibul, K1
Sonkon, P1
Tella, A1
Winkelmann, E1
Raether, W1
Wagner, WH1
Seow, CL1
Roy, OS1
Davidson, DE1
Johnsen, DO1
Tanticharoenyos, P1
Hickman, RL1
Kinnamon, KE1
Segal, HE2
Chinvanthananond, P1
Laixuthai, B1
Phintuyothin, P2
Na-Nakorn, A1
Castaneda, BF3
du Preez, O1
Cockcroft, CR1
Weber, MC1
de Clarke, V1
Harwin, RM2
Shiff, CJ1
Armstrong, JR1
Conteh, M1
de Francisco, A1
Hall, AJ1
Karwacki, JJ2
Suriyamongkol, V2
Watanasook, C2
Keuter, M1
van Eijk, A1
Hoogstrate, M1
Raasveld, M1
van de Ree, M1
Ngwawe, WA1
Watkins, WM2
Were, JB1
Brandling-Bennett, AD2
Allen, SJ1
Snow, RW4
Chandra, S1
Raina, R1
Sen, AB1
Saxena, M1
Saxena, AK1
Marsh, K1
Hayes, RH1
Carson, DC1
Otoo, L1
Shenton, F1
Byass, P3
Zavala, F1
Puri, SK1
Dutta, GP1
Davis, DR1
Hutton, DC1
Singharaj, P1
Shanks, D1
Pilungkasa, S1
Wasuwat, P1
Veenendaal, JR2
O'Donoghue, M1
Taylor, P1
Mutambu, SL1
Greenwood, AM2
Bradley, AK3
Hayes, RJ1
N'Jie, AB1
Hu, YM1
Wang, XX1
Deng, BZ1
Liu, FA1
Zhu, QP1
Kuang, MS1
Otoo, LN1
Heap, BJ1
Nevill, CG1
Carter, JY1
Boriga, DA1
Howells, RE1
Koech, DK1
Lee, PS2
Lau, EY1
Robinson, MJ1
Cook, IF4
Cochrane, JP1
Ti, TY2
Jacob, E1
Wee, YJ1
Hill, J1
Chiodini, PL1
Smith, AW1
Williams, K1
Eggelte, TA1
Huikeshoven, H1
de Wit, M1
Brown, GV1
Cook, GC1
Verdrager, J1
Newman, K1
Hyslop, R1
Monteagudo, FS1
Ames, JR1
Ryan, MD1
Klayman, DL1
Kovacic, P1
Lee, HS1
Yap, CL1
Panton, LJ1
Tulloch, S1
Danis, M1
Gentilini, M1
Kish, MY1
Donovan, KD1
Rebert, CC3
McCarthy, VC5
Miller, RM4
Miller, MB1
Bratton, JL1
Hanson, JP1
Cohen, M1
Reynolds, RD1
Lohr, DC1
Hunt, J1
Jilek, D1
Willerson, D2
Kass, L2
Carson, PE4
Frischer, H2
Richard, L1
Bowman, JE2
Brewer, GJ1
Powell, RD3
Shepard, CC1
Walker, LL1
Van Landingham, M1
Redus, MA1
Van Dyke, K1
Wallace, DC1
Ames, CW1
Campbell, CH1
Holiday, J1
Biggs, JC1
Backhouse, TC1
Imperato, PJ1
Shookhoff, HB1
Harvey, RP1
Arnold, JD1
Martin, DC1
Barrett-Connor, E1
Botelho, A1
Botha, D1
Laing, AB6
Elslager, EF1
Gooi, HC1
Gelber, RH1
Bairrington, JD1
Sulkowski, TS1
Merritt, JH1
Bernardini, AT1
Berman, SJ1
Hunsicker, LG1
Lucas, AO1
Hendrickse, RG1
Okubadejo, OA1
Richards, WH1
Neal, RA1
Kofie, BA1
DuPont, HL1
Music, SI1
Wolfensberger, HR1
Eppes, RB2
McNamara, JV1
DeGowin, RL2
Joy, RJ2
McCarty, JE1
Tigertt, WD3
Gardner, WR1
Dawkins, AT1
Cucinell, SA1
Chin, W1
Contacos, PG1
Coatney, GR1
Neff, TA1
Gaintner, JR1
Blount, RE1
Stickland, JF1
Hurdle, AD1
Cenedella, RJ2
Jarrell, JJ1
Ognibene, AJ1
Gregory, KG1
Prescott, B1
Saxe, LH1
Reback, H1
Cohen, RJ1
Sachs, JR1
Wicker, DJ1
Conrad, ME1
Schneider, MD1

Clinical Trials (10)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Non-Inferiority, Open-Labelled, Randomised Trial Of The Efficacy And Safety Of Artesunate-Amodiaquine, Artemether-Lumefantrine, And Artesunate-Lapdap For Treatment Of Uncomplicated P. Falciparum Malaria Among Children In Ghana[NCT00119145]Phase 4510 participants (Anticipated)Interventional2005-06-30Completed
Treating Malaria During Pregnancy: A Randomized Trial of Potential Options for Treatment in an Area of High Drug Resistance in Tanzania[NCT00146731]Phase 3310 participants (Actual)Interventional2004-01-31Completed
Drug Options for Intermittent Preventive Treatment for Malaria in Infants in an Area With High Resistance to Sulfadoxine/Pyrimethamine: an Evaluation of Short and Long-acting Antimalarial Drugs[NCT00158574]Phase 2/Phase 32,419 participants (Actual)Interventional2005-01-31Completed
Efficacy and Safety of Pediatric Immunization-linked Preventive Intermittent Treatment With Antimalarials in Decreasing Anemia and Malaria Morbidity in Rural Western Kenya[NCT00111163]1,516 participants Interventional2004-03-31Completed
Randomized Trial of the Safety and Effectiveness of Lapdap and Coartemether for Uncomplicated Malaria in Operational Settings[NCT00118794]Phase 31,200 participants Interventional2004-09-30Completed
Neuroprotective Effect of Dapsone in Patients With Aneurysmal Subarachnoid Hemorrhage: Prospective, Randomized, Double-Blinded, Placebo-Controlled, Clinical Trial[NCT05131295]Phase 349 participants (Actual)Interventional2007-09-05Completed
Pharmacokinetics of Chlorproguanil-Dapsone in Pregnant Women With Plasmodium Falciparum Infection, and Reinfection With P. Falciparum During Pregnancy Following Treatment[NCT00126971]Phase 1132 participants Interventional2005-07-31Suspended
Efficacy of Chloroquine (CQ) Alone Compared to Concomitant CQ and Primaquine (PQ) for the Treatment of Uncomplicated Plasmodium Vivax Infection[NCT02691910]Phase 2/Phase 3204 participants (Actual)Interventional2014-08-31Completed
A Longitudinal Study Assessing the Infectious Status and Immunity of Mothers and Their Children in Lambaréné, Including Intermittent Treatment of Children With Sulfadoxine-pyrimethamine for Malaria Control and Its Impact on Long-term Health[NCT00167843]Phase 41,189 participants Interventional2002-12-31Completed
Comparison of Two Strategies for Control of Malaria Within A Primary Health Care Programme in the Gambia[NCT00294580]Phase 42,253 participants Interventional1982-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

19 reviews available for dapsone and Malaria

ArticleYear
Current progress in antimalarial pharmacotherapy and multi-target drug discovery.
    European journal of medicinal chemistry, 2020, Feb-15, Volume: 188

    Topics: Animals; Antimalarials; Artemisinins; Drug Discovery; Drug Resistance; Humans; Malaria; Molecular St

2020
A short history of dapsone, or an alternative model of drug development.
    Journal of the history of medicine and allied sciences, 2011, Volume: 66, Issue:4

    Topics: Antimalarials; Dapsone; Drug Industry; History, 20th Century; Humans; Leprostatic Agents; Leprosy; M

2011
New antimalarial drugs.
    Angewandte Chemie (International ed. in English), 2003, Nov-10, Volume: 42, Issue:43

    Topics: Aminoquinolines; Animals; Antimalarials; Artemisinins; Artesunate; Atovaquone; Clinical Trials as To

2003
Chlorproguanil-dapsone for treating uncomplicated malaria.
    The Cochrane database of systematic reviews, 2004, Oct-18, Issue:4

    Topics: Adult; Antimalarials; Child; Dapsone; Drug Combinations; Humans; Malaria; Proguanil; Randomized Cont

2004
Chemoprophylaxis and intermittent treatment for preventing malaria in children.
    The Cochrane database of systematic reviews, 2005, Oct-19, Issue:4

    Topics: Antimalarials; Child, Preschool; Chloroquine; Dapsone; Humans; Infant; Malaria; Pyrimethamine; Rando

2005
Resisting resistance: dealing with the irrepressible problem of malaria.
    British journal of clinical pharmacology, 2006, Volume: 61, Issue:6

    Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Dapsone; Drug Combinations; Drug Resistance; H

2006
Falciparum malaria: the urgent need for safe and effective drugs.
    Annual review of medicine, 1983, Volume: 34

    Topics: Amodiaquine; Anti-Bacterial Agents; Antimalarials; Dapsone; Drug Combinations; Humans; Malaria; Plas

1983
Malaria 1984. Part I. Malaria prophylaxis.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1984, Jun-30, Volume: 65, Issue:26

    Topics: Antimalarials; Chloroquine; Dapsone; Drug Combinations; Drug Resistance, Microbial; Female; Humans;

1984
Recent work concerning anemia in the tropics.
    Seminars in hematology, 1982, Volume: 19, Issue:2

    Topics: Adolescent; Adult; Anemia; Anemia, Hypochromic; Anemia, Megaloblastic; Animals; Child; Child, Presch

1982
Drug interactions with antimalarial agents.
    Adverse drug reactions and toxicological reviews, 1999, Volume: 18, Issue:1

    Topics: Antimalarials; Dapsone; Drug Interactions; Humans; Malaria; Proguanil; Pyrimethamine; Quinolines; Su

1999
Malaria chemoprophylaxis: an update.
    Papua and New Guinea medical journal, 1987, Volume: 30, Issue:1

    Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Child, Preschool; Dapsone; Drug Combinations; Female;

1987
The chemoprophylaxis of malaria.
    The Journal of antimicrobial chemotherapy, 1987, Volume: 20, Issue:3

    Topics: Amodiaquine; Animals; Chloroquine; Dapsone; Drug Combinations; Drug Resistance; Malaria; Plasmodium

1987
Chemoprophylaxis of malaria.
    The Medical journal of Australia, 1986, Jun-23, Volume: 144, Issue:13

    Topics: Adolescent; Adult; Africa; Anemia, Hemolytic; Asia; Australia; Child; Child, Preschool; Chloroquine;

1986
The problem of drug resistance in malaria.
    Parasitology, 1985, Volume: 90 ( Pt 4)

    Topics: Africa; Animals; Antimalarials; Artemisinins; Chemical Phenomena; Chemistry; Chloroquine; Clinical T

1985
Summary of recent abstracts. 3. Malaria. 2.
    Tropical diseases bulletin, 1972, Volume: 69, Issue:4

    Topics: Animals; Antimalarials; Birds; Chloroquine; Dapsone; Humans; India; Malaria; Malaria, Avian; Mammals

1972
Summary of recent abstracts. 3. Malaria.2.
    Tropical diseases bulletin, 1973, Volume: 70, Issue:4

    Topics: Animals; Carbon Isotopes; Chloroquine; Dapsone; DNA; Drug Resistance, Microbial; Humans; Malaria; Or

1973
New perspectives on the chemotherapy of malaria, filariasis, and leprosy.
    Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques, 1974, Volume: 18

    Topics: Amodiaquine; Aniline Compounds; Antimalarials; Chloroquine; Cresols; Dapsone; Drug Resistance; Filar

1974
The pharmacology of the antimalarials. A rational approach to the therapy of resistant falciparum malaria.
    Archives of internal medicine, 1969, Volume: 123, Issue:6

    Topics: Amodiaquine; Antimalarials; Chemical Phenomena; Chemistry; Chloroquine; Dapsone; Drug Resistance, Mi

1969
Malaria. Chemoprophylaxis and chemotherapy.
    British medical journal, 1971, Apr-10, Volume: 2, Issue:5753

    Topics: Amodiaquine; Antimalarials; Chloroquine; Dapsone; Drug Resistance, Microbial; Drug Synergism; Humans

1971

Trials

35 trials available for dapsone and Malaria

ArticleYear
Risks of Hemolysis in Glucose-6-Phosphate Dehydrogenase Deficient Infants Exposed to Chlorproguanil-Dapsone, Mefloquine and Sulfadoxine-Pyrimethamine as Part of Intermittent Presumptive Treatment of Malaria in Infants.
    PloS one, 2015, Volume: 10, Issue:11

    Topics: Antimalarials; Cohort Studies; Dapsone; Double-Blind Method; Drug Combinations; Female; Genotype; Gl

2015
An open label, randomised trial of artesunate+amodiaquine, artesunate+chlorproguanil-dapsone and artemether-lumefantrine for the treatment of uncomplicated malaria.
    PloS one, 2008, Jun-25, Volume: 3, Issue:6

    Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Child; Child, Preschool; Dapsone;

2008
Randomized trial of artesunate+amodiaquine, sulfadoxine-pyrimethamine+amodiaquine, chlorproguanal-dapsone and SP for malaria in pregnancy in Tanzania.
    PloS one, 2009, Volume: 4, Issue:4

    Topics: Adult; Amodiaquine; Artemisinins; Artesunate; Dapsone; Drug Combinations; Drug Therapy, Combination;

2009
Measurement of adherence, drug concentrations and the effectiveness of artemether-lumefantrine, chlorproguanil-dapsone or sulphadoxine-pyrimethamine in the treatment of uncomplicated malaria in Malawi.
    Malaria journal, 2009, Aug-26, Volume: 8

    Topics: Adolescent; Adult; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Child; Ch

2009
Duration of protection against clinical malaria provided by three regimens of intermittent preventive treatment in Tanzanian infants.
    PloS one, 2010, Mar-01, Volume: 5, Issue:3

    Topics: Antimalarials; Dapsone; Drug Administration Schedule; Drug Combinations; Drug Resistance; Humans; Im

2010
Intermittent preventive treatment in infants for the prevention of malaria in rural Western kenya: a randomized, double-blind placebo-controlled trial.
    PloS one, 2010, Apr-02, Volume: 5, Issue:4

    Topics: Anemia; Antimalarials; Artemisinins; Artesunate; Dapsone; Double-Blind Method; Drug Combinations; Hu

2010
Randomized trial of safety and effectiveness of chlorproguanil-dapsone and lumefantrine-artemether for uncomplicated malaria in children in the Gambia.
    PloS one, 2011, Volume: 6, Issue:6

    Topics: Animals; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Aryl Hydrocarbon Hy

2011
Glucose-6-phosphate dehydrogenase deficiency, chlorproguanil-dapsone with artesunate and post-treatment haemolysis in African children treated for uncomplicated malaria.
    Malaria journal, 2012, Jul-10, Volume: 11

    Topics: Africa South of the Sahara; Anemia, Hemolytic; Antimalarials; Artemisinins; Artesunate; Case-Control

2012
Malaria chemoprophylaxis, infection of the placenta and birth weight in Gambian primigravidae.
    The Journal of tropical medicine and hygiene, 1994, Volume: 97, Issue:4

    Topics: Acute Disease; Antimalarials; Birth Weight; Chronic Disease; Dapsone; Double-Blind Method; Drug Comb

1994
Controlled trial of lambda-cyhalothrin impregnated bed nets and Maloprim chemosuppression to control malaria in children living in a holoendemic area of Sierra Leone, west Africa. Study design and preliminary results.
    Parassitologia, 1993, Volume: 35 Suppl

    Topics: Animals; Anopheles; Bedding and Linens; Child; Child, Preschool; Dapsone; Double-Blind Method; Drug

1993
Chloroquine-resistant malaria in Burma.
    The Journal of tropical medicine and hygiene, 1975, Volume: 78, Issue:8

    Topics: Chloroquine; Clinical Trials as Topic; Dapsone; Drug Resistance, Microbial; Humans; Malaria; Myanmar

1975
Chemosuppressive field trials in Thailand. III. The suppression of Plasmodium falciparum and Plasmodium vivax parasitemias by a sulfadoxine-pyrimethamine combination.
    The American journal of tropical medicine and hygiene, 1977, Volume: 26, Issue:6 Pt 1

    Topics: Blood; Clinical Trials as Topic; Dapsone; Drug Combinations; Female; Humans; Malaria; Male; Plasmodi

1977
Single-dose therapy of Falciparum malaria using pyrimethamine in combination with diformyldapsone or sulfadoxine.
    The American journal of tropical medicine and hygiene, 1976, Volume: 25, Issue:1

    Topics: Adolescent; Adult; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Evaluation; Humans; Ma

1976
Comparison of diaminodiphenylsulphonepyrimethamine and sulfadoxine-pyrimethamine combinations in the treatment of falciparum malaria in Thailand.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1975, Volume: 69, Issue:1

    Topics: Adolescent; Adult; Dapsone; Drug Evaluation; Drug Synergism; Female; Humans; Malaria; Male; Middle A

1975
Malaria prophylaxis.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1975, Aug-09, Volume: 49, Issue:34

    Topics: Chloroquine; Dapsone; Drug Combinations; Humans; Malaria; Military Medicine; Plasmodium falciparum;

1975
Chemosuppressive field trials in Thailand. II. The suppression of Plasmodium falciparum and Plasmodium vivax parasitemias by a diformyldapsone-pyrimethamine combination.
    The American journal of tropical medicine and hygiene, 1975, Volume: 24, Issue:6 Pt 1

    Topics: Adolescent; Adult; Aged; Antimalarials; Child; Dapsone; Drug Administration Schedule; Drug Evaluatio

1975
The effect of insecticide-treated bed nets on mortality of Gambian children.
    Lancet (London, England), 1991, Jun-22, Volume: 337, Issue:8756

    Topics: Antimalarials; Bedding and Linens; Child, Preschool; Community Health Workers; Dapsone; Drug Adminis

1991
Proguanil/sulfamethoxazole malaria chemoprophy-laxis on the Thai-Cambodian border.
    The Southeast Asian journal of tropical medicine and public health, 1991, Volume: 22, Issue:1

    Topics: Adult; Animals; Cambodia; Dapsone; Drug Resistance; Drug Therapy, Combination; Humans; Malaria; Male

1991
Comparison of chloroquine, pyrimethamine and sulfadoxine, and chlorproguanil and dapsone as treatment for falciparum malaria in pregnant and non-pregnant women, Kakamega District, Kenya.
    BMJ (Clinical research ed.), 1990, Sep-08, Volume: 301, Issue:6750

    Topics: Adolescent; Adult; Animals; Antimalarials; Chloroquine; Dapsone; Drug Therapy, Combination; Female;

1990
Compliance with malaria chemoprophylaxis over a five-year period among children in a rural area of The Gambia.
    The Journal of tropical medicine and hygiene, 1990, Volume: 93, Issue:5

    Topics: Antimalarials; Attitude of Health Personnel; Attitude to Health; Child, Preschool; Community Health

1990
Malaria prophylaxis with doxycycline in soldiers deployed to the Thai-Kampuchean border.
    The Southeast Asian journal of tropical medicine and public health, 1989, Volume: 20, Issue:1

    Topics: Antimalarials; Dapsone; Dose-Response Relationship, Drug; Doxycycline; Drug Combinations; Drug Evalu

1989
Comparison of two strategies for control of malaria within a primary health care programme in the Gambia.
    Lancet (London, England), 1988, May-21, Volume: 1, Issue:8595

    Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Community Health Workers; Dapsone; Drug Combina

1988
Comparison of two strategies for control of malaria within a primary health care programme in the Gambia.
    Lancet (London, England), 1988, May-21, Volume: 1, Issue:8595

    Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Community Health Workers; Dapsone; Drug Combina

1988
Comparison of two strategies for control of malaria within a primary health care programme in the Gambia.
    Lancet (London, England), 1988, May-21, Volume: 1, Issue:8595

    Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Community Health Workers; Dapsone; Drug Combina

1988
Comparison of two strategies for control of malaria within a primary health care programme in the Gambia.
    Lancet (London, England), 1988, May-21, Volume: 1, Issue:8595

    Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Community Health Workers; Dapsone; Drug Combina

1988
Immunity to malaria in young Gambian children after a two-year period of chemoprophylaxis.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1988, Volume: 82, Issue:1

    Topics: Animals; Antibodies, Protozoan; Antigens, Protozoan; Antimalarials; Child, Preschool; Cohort Studies

1988
Chlorproguanil/dapsone for the treatment of non-severe Plasmodium falciparum malaria in Kenya: a pilot study.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1988, Volume: 82, Issue:3

    Topics: Animals; Dapsone; Drug Therapy, Combination; Humans; Kenya; Malaria; Pilot Projects; Plasmodium falc

1988
The problem of drug resistance in malaria.
    Parasitology, 1985, Volume: 90 ( Pt 4)

    Topics: Africa; Animals; Antimalarials; Artemisinins; Chemical Phenomena; Chemistry; Chloroquine; Clinical T

1985
A field trial of pyrimethamine combined with dapsone in the chemoprophylaxis of malaria.
    The Central African journal of medicine, 1972, Volume: 18, Issue:10

    Topics: Clinical Trials as Topic; Dapsone; Drug Therapy, Combination; Humans; Malaria; Plasmodium falciparum

1972
Combinations of 4-aminobenzoic acid competitors and dihydrofolate dehydrogenase inhibitors in the chemotherapy of malaria. A commentary.
    Bulletin of the World Health Organization, 1974, Volume: 50, Issue:3-4

    Topics: Africa; Antimalarials; Asia; Chloroquine; Clinical Trials as Topic; Dapsone; Drug Evaluation; Drug R

1974
The suppression of malarial parasitaemia by pyrimethamine in combination with dapsone or sulphormethoxine.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1969, Volume: 63, Issue:2

    Topics: Adolescent; Antimalarials; Blood; Child; Clinical Trials as Topic; Dapsone; Escherichia coli; Feces;

1969
Studies on the chemotherapy of malaria. I. The treatment of overt falciparum malaria with potentiating combinations of pyrimethamine and sulphormethoxine or dapsone in The Gambia.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1970, Volume: 64, Issue:4

    Topics: Acute Disease; Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Dapsone; Drug Resistan

1970
Prophylactic and sporontocidal treatment of chloroquine resistant Plasmodium falciparum from Malaya.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1970, Volume: 64, Issue:6

    Topics: Adult; Amodiaquine; Anopheles; Antimalarials; Blood; Chloroquine; Clinical Trials as Topic; Dapsone;

1970
Prophylactic and sporontocidal treatment of chloroquine-resistant Plasmodium falciparum from Vietnam.
    The American journal of tropical medicine and hygiene, 1971, Volume: 20, Issue:1

    Topics: Adult; Antimalarials; Chloroquine; Clinical Trials as Topic; Dapsone; Humans; Malaria; Male; Methemo

1971
Malaria chemoprophylaxis with 4,4' diaminodiphenylsulfone (DDS). I. Field trial with comparison among companies of one division.
    Military medicine, 1969, Volume: 134, Issue:7

    Topics: Antimalarials; Clinical Trials as Topic; Dapsone; Humans; Malaria; Male; Military Medicine; United S

1969
Malaria chemoprophylaxis with 4,4' diaminodiphenylsulfone (DDS). II. Field trial with comparison between two divisions.
    Military medicine, 1969, Volume: 134, Issue:7

    Topics: Antimalarials; Clinical Trials as Topic; Dapsone; Humans; Malaria; Male; Military Medicine; United S

1969
Diformyl diaminodiphenyl sufone (DFD) as an antimalarial in man.
    Military medicine, 1970, Volume: 135, Issue:7

    Topics: Adult; Antimalarials; Chloroquine; Clinical Trials as Topic; Dapsone; Formates; Humans; Malaria; Mal

1970
The evaluation of quinine sulfate and diaminodiphenyl sulfone (DDS) as suppressive agents against sporozoite-induced Chesson strain vivax malaria.
    The American journal of tropical medicine and hygiene, 1966, Volume: 15, Issue:6

    Topics: Clinical Trials as Topic; Dapsone; Humans; Malaria; Plasmodium vivax; Quinine

1966

Other Studies

127 other studies available for dapsone and Malaria

ArticleYear
Antifolate studies. Activities of 40 potential antimalarial compounds against sensitive and chlorguanide triazine resistant strains of folate-requiring bacteria and Escherichia coli.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:2

    Topics: Animals; Antimalarials; Bacteria; Drug Resistance, Microbial; Escherichia coli; Folic Acid; Folic Ac

1977
Early childhood malaria prevention and children's patterns of school leaving in the Gambia.
    The British journal of educational psychology, 2014, Volume: 84, Issue:Pt 3

    Topics: Adolescent; Antimalarials; Child; Dapsone; Drug Combinations; Early Medical Intervention; Female; Fo

2014
A short history of dapsone, or an alternative model of drug development.
    Pharmacy in history, 2011, Volume: 53, Issue:4

    Topics: Antimalarials; Antitubercular Agents; Dapsone; History, 20th Century; Humans; Leprostatic Agents; Le

2011
Plasmodium berghei: efficacy of 5-fluoroorotate in combination with commonly used antimalarial drugs in a mouse model.
    Experimental parasitology, 2009, Volume: 121, Issue:4

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Dapsone; Drug Synergism; Drug Therapy, Combination

2009
Assessing the consistency assumption by exploring treatment by covariate interactions in mixed treatment comparison meta-analysis: individual patient-level covariates versus aggregate trial-level covariates.
    Statistics in medicine, 2012, Dec-20, Volume: 31, Issue:29

    Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Dap

2012
Studies on the toxicity and action of diaminodiphenyl-sulfone (DDS) in avian and simian malaria.
    Bulletin of the World Health Organization, 1962, Volume: 27

    Topics: Animals; Antimalarials; Birds; Chloroquine; Dapsone; Malaria; Malaria, Avian; Proguanil; Pyrimethami

1962
POTENTIATION OF ACTIVITY OF DIAPHENYLSULFONE AND PYRIMETHAMINE AGAINST PLASMODIUM GALLINACEUM AND PLASMODIUM CYNOMOLGI BASTIANELLII.
    Bulletin of the World Health Organization, 1964, Volume: 31

    Topics: Animals; Dapsone; Drug Resistance; Drug Resistance, Microbial; Haplorhini; Malaria; Pharmacology; Pl

1964
LABORATORY STUDIES ON THE REPOSITORY ANTIMALARIAL ACTIVITY OF 4,4'-DIACETYLAMINODIPHENYLSULFONE, ALONE AND MIXED WITH CYCLOGUANIL PAMOATE (CI-501).
    The American journal of tropical medicine and hygiene, 1965, Volume: 14

    Topics: Animals; Antimalarials; Dapsone; Haplorhini; Malaria; Mice; Pharmacology; Proguanil; Research; Triaz

1965
The chemotherapy of rodent malaria. LXIII. Drug combinations to impede the selection of drug resistance, part 6: the potential value of chlorproguanil and dapsone in combination, and with the addition of artesunate.
    Annals of tropical medicine and parasitology, 2005, Volume: 99, Issue:5

    Topics: Animals; Antimalarials; Artemisinins; Artesunate; Dapsone; Drug Resistance; Drug Synergism; Drug The

2005
Pharmacologic advances in the global control and treatment of malaria: combination therapy and resistance.
    Clinical pharmacology and therapeutics, 2007, Volume: 82, Issue:5

    Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Artesunate; Chloroquine; Dapsone; Drug Design;

2007
Treatment of chloroquine-resistant Plasmodium falciparum infections in Vietnam.
    Annals of internal medicine, 1967, Volume: 66, Issue:3

    Topics: Chloroquine; Dapsone; Humans; Malaria; Military Medicine; Pyrimethamine; Quinacrine; Quinine; Sulfad

1967
Antimalarial effect of diaphenylsulfone and three sulfonamides among semi-immune Africans.
    The American journal of tropical medicine and hygiene, 1967, Volume: 16, Issue:1

    Topics: Adolescent; Black or African American; Black People; Child; Dapsone; Humans; Immunity; Malaria; Sulf

1967
Chemotherapy of sporozoite- and blood-induced Plasmodium berghei infections with selected antimalarial agents.
    The American journal of tropical medicine and hygiene, 1967, Volume: 16, Issue:5

    Topics: Animals; Chloroquine; Cricetinae; Dapsone; Malaria; Mice; Primaquine; Pyrimethamine; Quinine; Rats

1967
Reactions to dapsone.
    Lancet (London, England), 1981, Sep-12, Volume: 2, Issue:8246

    Topics: Agranulocytosis; Dapsone; Drug Combinations; Humans; Malaria; Medication Errors; Pyrimethamine

1981
Chemoprophylaxis of malaria in non-immune residents in Dar es Salaam, Tanzania.
    Lancet (London, England), 1984, Sep-22, Volume: 2, Issue:8404

    Topics: Adolescent; Adult; Aged; Antimalarials; Child; Child, Preschool; Chloroquine; Dapsone; Drug Administ

1984
Long-acting, repository antimalarial agents. Duration of protection in mice and monkeys following administration of pyrimethamine pamoate.
    The American journal of tropical medicine and hygiene, 1984, Volume: 33, Issue:4

    Topics: Acedapsone; Animals; Dapsone; Drug Combinations; Female; Injections, Intramuscular; Macaca fascicula

1984
Treatment of falciparum malaria with a single dose combination of dapsone and pyrimethamine (Maloprim).
    Singapore medical journal, 1983, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Antimalarials; Child; Child, Preschool; Dapsone; Drug Combinations; Female; Human

1983
Malaria chemoprophylaxis--which drug?
    Papua and New Guinea medical journal, 1983, Volume: 26, Issue:2

    Topics: Adult; Antimalarials; Child, Preschool; Chloroquine; Dapsone; Drug Combinations; Drug Resistance, Mi

1983
Activities of respository preparations of cycloguanil pamoate and 4,4'-diacetyldiaminodiphenylsulfone, alone and in combination, against infections with Plasmodium cynomolgi in rhesus monkeys.
    Antimicrobial agents and chemotherapy, 1984, Volume: 26, Issue:5

    Topics: Acedapsone; Animals; Antimalarials; Dapsone; Drug Combinations; Drug Resistance, Microbial; Macaca m

1984
Malaria in Christchurch.
    Pathology, 1984, Volume: 16, Issue:4

    Topics: Chloroquine; Dapsone; Drug Combinations; Humans; Malaria; New Zealand; Plasmodium falciparum; Plasmo

1984
Chemoprophylaxis of malaria in Africa.
    British medical journal (Clinical research ed.), 1983, Feb-12, Volume: 286, Issue:6364

    Topics: Agranulocytosis; Antimalarials; Dapsone; Drug Combinations; Humans; Malaria; Male; Middle Aged; Pyri

1983
Agranulocytosis associated with malaria prophylaxis with Maloprim.
    British medical journal (Clinical research ed.), 1983, Apr-16, Volume: 286, Issue:6373

    Topics: Adult; Aged; Agranulocytosis; Antimalarials; Dapsone; Drug Combinations; Female; Humans; Malaria; Ma

1983
Agranulocytosis associated with Maloprim.
    British medical journal (Clinical research ed.), 1983, May-07, Volume: 286, Issue:6376

    Topics: Aged; Agranulocytosis; Dapsone; Drug Combinations; Female; Humans; Malaria; Middle Aged; Pyrimethami

1983
Malaria prophylaxis for long term visitors.
    British medical journal (Clinical research ed.), 1983, Nov-12, Volume: 287, Issue:6403

    Topics: Antimalarials; Chloroquine; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Malaria;

1983
Maloprim--general toxicity or idiosyncrasy?
    Papua and New Guinea medical journal, 1984, Volume: 27, Issue:1

    Topics: Adult; Agranulocytosis; Dapsone; Drug Combinations; Female; Humans; Malaria; Pyrimethamine

1984
Red cell hypoplasia following dapsone and pyrimethamine.
    The Central African journal of medicine, 1983, Volume: 29, Issue:9

    Topics: Aged; Anemia, Aplastic; Dapsone; Humans; Malaria; Male; Pyrimethamine

1983
Malaria incidence in leprosy patients under dapsone therapy in Karbi-Anglong district, Assam.
    The Journal of communicable diseases, 1982, Volume: 14, Issue:2

    Topics: Adult; Antimalarials; Child; Dapsone; Humans; India; Leprosy; Malaria; Plasmodium falciparum

1982
Drug prevention of malaria.
    British medical journal (Clinical research ed.), 1981, Mar-21, Volume: 282, Issue:6268

    Topics: Dapsone; Drug Combinations; Humans; Malaria; Pyrimethamine

1981
Treatment of malaria.
    The New Zealand medical journal, 1980, Mar-12, Volume: 91, Issue:655

    Topics: Dapsone; Drug Therapy, Combination; Humans; Malaria; Primaquine; Pyrimethamine

1980
Malaria in southeast Queensland in 1979.
    The Medical journal of Australia, 1980, Dec-13, Volume: 2, Issue:12

    Topics: Adolescent; Adult; Australia; Child; Child, Preschool; Chloroquine; Dapsone; Female; Humans; Infant;

1980
Malaria prophylaxis.
    The Medical journal of Australia, 1981, Aug-22, Volume: 2, Issue:4

    Topics: Antimalarials; Dapsone; Drug Combinations; Humans; Malaria; Plasmodium falciparum; Pyrimethamine; Tr

1981
Haemoglobinuria after a single dose treatment with dapsone and pyrimethamine for falciparum malaria in a patient with glucose-6-phosphate dehydrogenase deficiency.
    Tropical and geographical medicine, 1981, Volume: 33, Issue:4

    Topics: Child, Preschool; Dapsone; Drug Combinations; Glucosephosphate Dehydrogenase; Glucosephosphate Dehyd

1981
Malaria prophylaxis: guidelines for travellers from Britain. Malaria Reference Laboratory of the Public Health Laboratory Service, London.
    BMJ (Clinical research ed.), 1995, Mar-18, Volume: 310, Issue:6981

    Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Culicidae; Dapsone; Doxycycline;

1995
Oxidative activation of proguanil and dapsone acetylation in Thai soldiers.
    British journal of clinical pharmacology, 1994, Volume: 37, Issue:1

    Topics: Acetylation; Biotransformation; Chromatography, High Pressure Liquid; Dapsone; Humans; Malaria; Mili

1994
A malaria control trial using insecticide-treated bed nets and targeted chemoprophylaxis in a rural area of The Gambia, west Africa. 6. The impact of the interventions on mortality and morbidity from malaria.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1993, Volume: 87 Suppl 2

    Topics: Antimalarials; Child, Preschool; Chloroquine; Dapsone; Drug Combinations; Gambia; Humans; Hygiene; I

1993
A malaria control trial using insecticide-treated bed nets and targeted chemoprophylaxis in a rural area of The Gambia, west Africa. 8. Cost-effectiveness of bed net impregnation alone or combined with chemoprophylaxis in preventing mortality and morbidit
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1993, Volume: 87 Suppl 2

    Topics: Antimalarials; Bedding and Linens; Child, Preschool; Cost-Benefit Analysis; Dapsone; Drug Combinatio

1993
Malaria prophylaxis prescribed for travellers from New Zealand.
    The New Zealand medical journal, 1997, Aug-22, Volume: 110, Issue:1050

    Topics: Antimalarials; Chloroquine; Dapsone; Drug Combinations; Drug Utilization; Humans; Malaria; New Zeala

1997
[Chemoprophylaxis of malaria in travelers to endemic zones].
    Revista clinica espanola, 1998, Volume: 198, Issue:6

    Topics: Antimalarials; Chloroquine; Dapsone; Doxycycline; Drug Resistance; Drug Therapy, Combination; Humans

1998
Hypersensitivity syndrome associated with dapsone/pyrimethamine (Maloprim) antimalaria chemoprophylaxis.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2002, Volume: 88, Issue:5

    Topics: Adult; Antimalarials; Dapsone; Drug Combinations; Drug Hypersensitivity; Glucocorticoids; Humans; Ma

2002
Malaria prophylaxis for visitors to Papua New Guinea.
    The Medical journal of Australia, 1978, Oct-07, Volume: 2, Issue:8

    Topics: Dapsone; Drug Therapy, Combination; Humans; Malaria; New Guinea; Plasmodium falciparum; Pyrimethamin

1978
Falciparum malaria despite chemoprophylaxis.
    British medical journal, 1979, May-19, Volume: 1, Issue:6174

    Topics: Chloroquine; Dapsone; Drug Combinations; Humans; Malaria; Plasmodium falciparum; Pyrimethamine

1979
Malaria in Australia.
    The Medical journal of Australia, 1979, Jun-30, Volume: 1, Issue:13

    Topics: Australia; Chloroquine; Dapsone; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum;

1979
Experimental studies on the effect of proguanil and dapsone against chloroquine-resistant Plasmodium berghei (ANKA) in white mice.
    Annals of tropical medicine and parasitology, 1979, Volume: 73, Issue:1

    Topics: Animals; Chloroquine; Dapsone; Dose-Response Relationship, Drug; Drug Resistance; Drug Therapy, Comb

1979
Treatment and chemoprophylaxis of malaria.
    The Practitioner, 1979, Volume: 223, Issue:1336

    Topics: Aminoquinolines; Antimalarials; Biguanides; Chloroquine; Dapsone; Humans; Malaria; Plasmodium falcip

1979
Determination of plasma concentrations of dapsone, monoacetyl dapsone and pyrimethamine in human subjects dosed with maloprim.
    Journal of chromatography, 1979, Jun-11, Volume: 163, Issue:2

    Topics: Adult; Chromatography, High Pressure Liquid; Dapsone; Drug Combinations; Half-Life; Humans; Malaria;

1979
Studies on Azadiracta indica in malaria [proceedings].
    British journal of pharmacology, 1976, Volume: 58, Issue:2

    Topics: Animals; Dapsone; Malaria; Male; Mice; Plant Extracts; Plants, Medicinal; Plasmodium berghei

1976
[Chemotherapeutically active nitro compounds. 2nd communication: Nitrodiphenyl sulfones (author's transl)].
    Arzneimittel-Forschung, 1976, Volume: 26, Issue:8

    Topics: Animals; Dapsone; Malaria; Mice; Mice, Inbred Strains; Mycobacterium bovis; Mycobacterium Infections

1976
A comparative study of the efficacy of chloroquine and a combination of dapsone and pyrimethamine in the prophylaxis of malaria in Peninsular Malaysia.
    The Journal of tropical medicine and hygiene, 1976, Volume: 79, Issue:10

    Topics: Adult; Child; Chloroquine; Dapsone; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; M

1976
Evaluating new antimalarial drugs against trophozoite induced Plasmodium cynomolgi malaria in rhesus monkeys.
    The American journal of tropical medicine and hygiene, 1976, Volume: 25, Issue:1

    Topics: Amodiaquine; Animals; Antimalarials; Dapsone; Disease Models, Animal; Dose-Response Relationship, Dr

1976
Breakthrough in fight against malaria.
    The Australasian nurses journal, 1975, Volume: 3, Issue:7

    Topics: Community Health Workers; Dapsone; Drug Combinations; Drug Evaluation; Humans; Infant; Malaria; Pyri

1975
Letter: Prevention of chloroquine-resistant falciparum malaria.
    Annals of internal medicine, 1975, Volume: 82, Issue:4

    Topics: Chloroquine; Dapsone; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Malaria; Plasmo

1975
An extended field trial of pyrimethamine combined with dapsone in the prophylaxis of malaria.
    The Central African journal of medicine, 1975, Volume: 21, Issue:9

    Topics: Adolescent; Adult; Child; Child, Preschool; Dapsone; Drug Therapy, Combination; Humans; Infant; Mala

1975
Antimalarial activity of some 4-alkylamino 2/3 methoxy-4-aminodiphenyl sulphones.
    Indian journal of malariology, 1990, Volume: 27, Issue:3

    Topics: Animals; Antimalarials; Dapsone; Malaria; Male; Mice; Molecular Structure; Plasmodium berghei

1990
Anti-sporozoite antibodies and immunity to malaria in a rural Gambian population.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1988, Volume: 82, Issue:4

    Topics: Age Factors; Animals; Antibodies, Protozoan; Antimalarials; Child; Child, Preschool; Dapsone; Drug C

1988
Malaria in travelers returning from Kenya: failure of self-treatment with pyrimethamine/sulfadoxine.
    MMWR. Morbidity and mortality weekly report, 1989, May-26, Volume: 38, Issue:20

    Topics: Animals; Antimalarials; Dapsone; Drug Combinations; Humans; Kenya; Malaria; Plasmodium falciparum; P

1989
Delay in emergence of mefloquine resistance in Plasmodium berghei by use of drug combinations.
    Acta tropica, 1989, Volume: 46, Issue:4

    Topics: Animals; Antimalarials; Dapsone; Drug Resistance; Drug Therapy, Combination; Erythromycin; Malaria;

1989
Plasmodium vivax resistance to chloroquine?
    Lancet (London, England), 1989, Nov-18, Volume: 2, Issue:8673

    Topics: Acute Disease; Animals; Antimalarials; Blood Specimen Collection; Chloroquine; Dapsone; Drug Adminis

1989
Failure of dapsone/pyrimethamine plus chloroquine against falciparum malaria in Papua New Guinea.
    Lancet (London, England), 1988, Jan-30, Volume: 1, Issue:8579

    Topics: Adult; Animals; Chloroquine; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Malaria;

1988
Compliance with malaria chemoprophylaxis programmes in Zimbabwe.
    Acta tropica, 1987, Volume: 44, Issue:4

    Topics: Chloroquine; Dapsone; Humans; Malaria; Patient Compliance; Pyrimethamine; Zimbabwe

1987
[Action of nitroquine on tissue schizonts of Plasmodium cynomolgi].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1986, Volume: 7, Issue:1

    Topics: Animals; Antimalarials; Dapsone; Female; Macaca mulatta; Malaria; Male; Plasmodium; Quinazolines; Re

1986
Malaria chemoprophylaxis with a proguanil-chloroquine-maloprim combination in Papua New Guinea.
    Journal of the Royal Army Medical Corps, 1988, Volume: 134, Issue:3

    Topics: Animals; Antimalarials; Chloroquine; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans;

1988
Risk of acute non-specific upper respiratory tract infections in healthy men taking dapsone-pyrimethamine for prophylaxis against malaria.
    British medical journal (Clinical research ed.), 1988, Mar-26, Volume: 296, Issue:6626

    Topics: Acute Disease; Adolescent; Antimalarials; Dapsone; Drug Combinations; Humans; Immunosuppression Ther

1988
Malaria in north-eastern Botswana.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1988, Oct-15, Volume: 74, Issue:8

    Topics: Botswana; Dapsone; Drug Therapy, Combination; Humans; Malaria; Pyrimethamine; Sulfadoxine; Sulfanila

1988
Race-linked differences in serum concentrations of dapsone, monoacetyldapsone and pyrimethamine during malaria prophylaxis.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1986, Volume: 80, Issue:6

    Topics: Adolescent; Adult; Biological Availability; Black People; Dapsone; Drug Combinations; Female; Humans

1986
The effect of dapsone-pyrimethamine on immunoglobulin concentrations in malaria chemoprophylaxis.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1987, Volume: 81, Issue:2

    Topics: Adolescent; Adult; Antimalarials; Dapsone; Depression, Chemical; Drug Combinations; Humans; Immunogl

1987
The activity of drug combinations against established infections of rodent malaria.
    Parasitology, 1987, Volume: 95 ( Pt 1)

    Topics: Animals; Antimalarials; Chloroquine; Dapsone; Drug Therapy, Combination; Malaria; Mice; Plasmodium b

1987
ELISA tests for dapsone and pyrimethamine and their application in a malaria chemoprophylaxis programme.
    Bulletin of the World Health Organization, 1986, Volume: 64, Issue:6

    Topics: Child, Preschool; Dapsone; Drug Combinations; Enzyme-Linked Immunosorbent Assay; Gambia; Humans; Inf

1986
Serious problems with antimalarial drugs.
    The Journal of infection, 1986, Volume: 13, Issue:1

    Topics: Antimalarials; Chloroquine; Dapsone; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Co

1986
Epidemiology of the emergence and spread of drug-resistant falciparum malaria in South-East Asia and Australasia.
    The Journal of tropical medicine and hygiene, 1986, Volume: 89, Issue:6

    Topics: Antimalarials; Asia, Southeastern; Cambodia; Chloroquine; Dapsone; Drug Combinations; Drug Resistanc

1986
Excretion of chloroquine, dapsone and pyrimethamine in human milk.
    British journal of clinical pharmacology, 1986, Volume: 22, Issue:6

    Topics: Adult; Chloroquine; Dapsone; Drug Combinations; Female; Humans; Malaria; Milk, Human; Pregnancy; Pyr

1986
Malaria prophylaxis.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1986, Sep-13, Volume: 70, Issue:6

    Topics: Antimalarials; Child; Chloroquine; Dapsone; Drug Combinations; Female; Humans; Malaria; Pregnancy; P

1986
Charge transfer and oxy radicals in antimalarial action. Quinones, dapsone metabolites, metal complexes, iminium ions, and peroxides.
    Journal of free radicals in biology & medicine, 1985, Volume: 1, Issue:5-6

    Topics: Aminacrine; Aminoquinolines; Biguanides; Dapsone; Electron Transport; Free Radicals; Imines; Ions; M

1985
Inadequate prophylaxis of malaria with dapsone-pyrimethamine.
    The Medical journal of Australia, 1985, Mar-18, Volume: 142, Issue:6

    Topics: Adolescent; Adult; Antimalarials; Biological Availability; Child; Dapsone; Drug Combinations; Drug R

1985
Malaria prophylaxis for travellers.
    The Medical journal of Australia, 1985, Apr-01, Volume: 142, Issue:7

    Topics: Dapsone; Drug Combinations; Humans; Malaria; Plasmodium falciparum; Plasmodium vivax; Pyrimethamine;

1985
Malaria prophylaxis for Canadian travellers.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1985, Nov-15, Volume: 133, Issue:10

    Topics: Amodiaquine; Canada; Chloroquine; Dapsone; Doxycycline; Drug Combinations; Drug Resistance, Microbia

1985
Simultaneous estimation of serum concentrations of dapsone, monoacetyldapsone, and pyrimethamine in Chinese men on maloprim for malaria prophylaxis using reversed-phase high performance liquid chromatography.
    Therapeutic drug monitoring, 1985, Volume: 7, Issue:4

    Topics: Acetylation; Adolescent; Adult; China; Chromatography, High Pressure Liquid; Dapsone; Drug Administr

1985
Susceptibility of Plasmodium falciparum in The Gambia to pyrimethamine, Maloprim and chloroquine.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1985, Volume: 79, Issue:4

    Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Dapsone; Dose-Response Relationship, Drug; Drug

1985
[Malaria chemoprophylaxis. Resistance problems].
    Archives francaises de pediatrie, 1985, Volume: 42 Suppl 2

    Topics: Antimalarials; Child; Child, Preschool; Chloroquine; Dapsone; Drug Combinations; Drug Resistance, Mi

1985
Haematological safety of long-term malarial prophylaxis with dapsone-pyrimethamine.
    The Medical journal of Australia, 1985, Aug-19, Volume: 143, Issue:4

    Topics: Adolescent; Adult; Age Factors; Antimalarials; Child; Child, Preschool; Dapsone; Drug Combinations;

1985
Maloprim for malaria prophylaxis.
    The Medical journal of Australia, 1985, Sep-30, Volume: 143, Issue:7

    Topics: Antimalarials; Dapsone; Drug Combinations; Humans; Malaria; Pyrimethamine

1985
Drug-resistant malaria.
    Lancet (London, England), 1969, Jun-21, Volume: 1, Issue:7608

    Topics: Chloroquine; Dapsone; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Primaquine

1969
Prophylaxis of malaria in man using the sulfone DFD with pyrimethamine.
    Military medicine, 1973, Volume: 138, Issue:7

    Topics: Chloroquine; Dapsone; Formaldehyde; Humans; Malaria; Male; Plasmodium falciparum; Plasmodium vivax;

1973
Experience with mixed infections of Plasmodium falciparum and vivax.
    Military medicine, 1973, Volume: 138, Issue:9

    Topics: Antimalarials; Chloroquine; Dapsone; Humans; Malaria; Military Medicine; Plasmodium falciparum; Plas

1973
Chemotherapeutic results in a multi-drug resistant strain of Plasmodium falciparum malaria from Vietnam.
    Military medicine, 1974, Volume: 139, Issue:3

    Topics: Adult; Alanine Transaminase; Anopheles; Antimalarials; Aspartate Aminotransferases; Dapsone; Drug Re

1974
Effects of diaphenylsulphone (dapsone) against Plasmodium vivax of South West Pacific origin.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1968, Volume: 62, Issue:5

    Topics: Adult; Child; Chloroquine; Culicidae; Dapsone; Drug Resistance, Microbial; Humans; Insect Vectors; M

1968
Kinetic testing of drugs against Mycobacterium leprae in mice. Activity of cephaloridine, rifampin, streptovaricin, vadrine, and viomycin.
    The American journal of tropical medicine and hygiene, 1971, Volume: 20, Issue:4

    Topics: Animals; Antimalarials; Cephaloridine; Dapsone; Diet; Evaluation Studies as Topic; Injections, Subcu

1971
The chemoprophylactic use of diformyl diaminodiphenyl sulfone (DFD) in falciparum malaria.
    The American journal of tropical medicine and hygiene, 1972, Volume: 21, Issue:2

    Topics: Adult; Anopheles; Antimalarials; Blood Cell Count; Chloroquine; Dapsone; Drug Resistance, Microbial;

1972
Quinine infusion for recrudescences of falciparum malaria in Vietnam: a controlled study.
    The American journal of tropical medicine and hygiene, 1972, Volume: 21, Issue:6

    Topics: Dapsone; Humans; Infusions, Parenteral; Malaria; Plasmodium falciparum; Pyrimethamine; Quinine; Recu

1972
DDS: mechanisms of action and structure-activity relationships.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 200, Issue:1

    Topics: Adenosine; Animals; Biological Transport; Cell Membrane Permeability; Dapsone; Leprosy; Malaria; Pla

1972
Responsibility for failure of sulphonamides in falciparum malaria; host or parasite?
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1972, Volume: 66, Issue:5

    Topics: Dapsone; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falciparum; Sulfonamides

1972
Recrudescent falciparum malaria in Vietnam.
    The American journal of tropical medicine and hygiene, 1973, Volume: 22, Issue:3

    Topics: Adult; Black People; Dapsone; Fever; Follow-Up Studies; Humans; Malaria; Male; Military Medicine; Pl

1973
Malaria in the Australian army in South Vietnam: successful use of a proguanil-dapsone combination for chemoprophylaxis of chloroquine-resistant falciparum malaria.
    The Medical journal of Australia, 1973, Jun-30, Volume: 1, Issue:26

    Topics: Australia; Chloroquine; Dapsone; Disease Outbreaks; Drug Resistance, Microbial; Humans; Malaria; Mil

1973
Letter: Malaria in the Australian army in South Vietnam.
    The Medical journal of Australia, 1973, Sep-15, Volume: 2, Issue:11

    Topics: Australia; Dapsone; Humans; Malaria; Military Medicine; Plasmodium falciparum; Plasmodium vivax; Pro

1973
Letter: Malaria in the Australian army in South Vietnam.
    The Medical journal of Australia, 1973, Sep-08, Volume: 2, Issue:10

    Topics: Dapsone; Disease Outbreaks; Drug Resistance, Microbial; Humans; Malaria; Male; Military Medicine; Pl

1973
The suppression of Plasmodium falciparum and Plasmodium vivax parasitaemias by a dapsone-pyrimethamine combination.
    The Journal of tropical medicine and hygiene, 1973, Volume: 76, Issue:11

    Topics: Adolescent; Adult; Child; Chloroquine; Dapsone; Drug Combinations; Female; Hematocrit; Humans; Malar

1973
Chloroquine-resistant Falciparum malaria acquired in Vietnam.
    The Medical journal of Australia, 1973, Oct-13, Volume: 2, Issue:15

    Topics: Acute Kidney Injury; Adolescent; Adult; Blood Cell Count; Chloroquine; Dapsone; Drug Resistance, Mic

1973
Malaria in New York City. IV. 1960-1971.
    The Journal of tropical medicine and hygiene, 1974, Volume: 77, Issue:1

    Topics: Adolescent; Adult; Africa, Western; Age Factors; Amodiaquine; Child; Child, Preschool; Chloroquine;

1974
A comparison between the quinine and chloroquine regimens for falciparum malaria in Vietnam.
    The Southeast Asian journal of tropical medicine and public health, 1974, Volume: 5, Issue:1

    Topics: Administration, Oral; Chloroquine; Dapsone; Humans; Injections, Intravenous; Malaria; Male; Military

1974
Chemoprophylaxis of malaria for travelers.
    Annals of internal medicine, 1974, Volume: 81, Issue:2

    Topics: Africa; Antimalarials; Asia; Central America; Chloroquine; Dapsone; Drug Resistance, Microbial; Drug

1974
Considerations on the use of sulphones and sulphonamides with a pyrimidine derivative.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1974, Jun-09, Volume: 48, Issue:31

    Topics: Adult; Amodiaquine; Child; Dapsone; Drug Combinations; Drug Resistance, Microbial; Humans; Malaria;

1974
Some pharmacological aspects of antimalarial drugs.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1974, Jun-15, Volume: 48, Issue:29

    Topics: Antimalarials; Chloroquine; Dapsone; Drug Resistance, Microbial; Humans; Malaria; Plasmodium falcipa

1974
Treatment of drug-resistant malaria in man.
    Bulletin of the World Health Organization, 1974, Volume: 50, Issue:3-4

    Topics: Africa; Antimalarials; Asia; Central America; Dapsone; Drug Resistance; Drug Therapy, Combination; H

1974
Letter: An acute attack of quartan malaria in a leprosy patient being treated with diaminodiphenylsulphone.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1974, Volume: 68, Issue:2

    Topics: Acute Disease; Adult; Dapsone; Humans; Leprosy; Malaria; Malaysia; Male; Plasmodium malariae

1974
Reduced pressure potentiation of the side effects of the antimalarial, Dapsone.
    Aerospace medicine, 1967, Volume: 38, Issue:11

    Topics: Aerospace Medicine; Altitude; Anemia; Animals; Asia, Southeastern; Dapsone; Erythrocyte Count; Hyper

1967
Antimalarial effects of sulphormethoxine, diaphenylsulphone and separate combinations of these with pyrimethamine: a review of preliminary investigations carried out in Tanzania.
    The Journal of tropical medicine and hygiene, 1968, Volume: 71, Issue:2

    Topics: Adolescent; Adult; Antimalarials; Child; Chloroquine; Dapsone; Drug Hypersensitivity; Drug Resistanc

1968
Chloroquine-pyrimethamine-sulfisoxazole therapy of Plasmodium falciparum malaria. An alternative to quinine.
    JAMA, 1969, Jan-06, Volume: 207, Issue:1

    Topics: Chloroquine; Dapsone; Drug Resistance, Microbial; Fever; Humans; Malaria; Male; Military Medicine; P

1969
Studies on the chemotherapy of malaria. II. Pyrimethamine resistance in The Gambia.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1970, Volume: 64, Issue:4

    Topics: Carrier State; Child; Child, Preschool; Dapsone; Drug Resistance, Microbial; Erythrocytes; Female; G

1970
Curative and suppressive treatment of P. falciparum malaria with oral and parenteral Fansidar.
    The Southeast Asian journal of tropical medicine and public health, 1971, Volume: 2, Issue:1

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Child; Child, Preschool; Chloroquine; Dapson

1971
Chloroquine-resistant Plasmodium falciparum: protective and hemolytic effects of 4,4'-diaminodiphenylsulfone (DDS) administered daily together with weekly chloroquine and primaquine.
    Military medicine, 1967, Volume: 132, Issue:3

    Topics: Adult; Black or African American; Chloroquine; Dapsone; Hemolysis; Humans; Malaria; Male; Plasmodium

1967
Prophylaxis of malaria in man using the sulfones DFD and DDS alone and with chloroquine.
    Military medicine, 1971, Volume: 136, Issue:11

    Topics: Adult; Chloroquine; Dapsone; Humans; Malaria; Male; Sulfones

1971
The effects of diaphenylsulfone (DDS) against chloroquine-resistant Plasmodium falciparum.
    Bulletin of the World Health Organization, 1966, Volume: 34, Issue:5

    Topics: Adult; Aminobenzoates; Dapsone; Drug Resistance, Microbial; Humans; Malaria; Male; Plasmodium falcip

1966
Supplemental sulfone (dapsone) therapy. Use in treatment of chloroquine-resistant falciparum malaria.
    Archives of internal medicine, 1967, Volume: 119, Issue:6

    Topics: Adolescent; Adult; Anemia, Hemolytic; Chemical Phenomena; Chemistry, Physical; Dapsone; Humans; Mala

1967
Management of chloroquine resistant falciparum malaria.
    Transactions of the American Clinical and Climatological Association, 1967, Volume: 78

    Topics: Adult; Brain Diseases; Chloroquine; Dapsone; Dexamethasone; Drug Resistance, Microbial; Edema; Human

1967
Agranulocytosis probably due to dapsone in an infantry soldier.
    The Medical journal of Australia, 1970, May-09, Volume: 1, Issue:19

    Topics: Adult; Agranulocytosis; Australia; Dapsone; Humans; Malaria; Male; Military Personnel; Pseudomonas I

1970
Suggested new mechanisms of antimalarial action for DDS involving inhibition of glucose utilization by the intraerythrocytic parasite.
    The American journal of tropical medicine and hygiene, 1970, Volume: 19, Issue:4

    Topics: Aminobenzoates; Animals; Autoanalysis; Biological Transport; Cell Membrane; Dapsone; Erythrocytes; F

1970
Agranulocytosis due to dapsone.
    Annals of internal medicine, 1970, Volume: 72, Issue:4

    Topics: Adult; Agranulocytosis; Dapsone; Humans; Malaria; Male; Military Medicine; Time Factors; Tropical Me

1970
The chemotherapy of rodent malaria. IX. Causal prophylaxis. I. A method for demonstrating drug action on exo-erythrocytic stages.
    Annals of tropical medicine and parasitology, 1970, Volume: 64, Issue:1

    Topics: Animals; Antimalarials; Chloroquine; Dapsone; Malaria; Male; Mice; Plasmodium; Primaquine; Proguanil

1970
Potential antimalarial agents derivatives of 4,4'- diaminodiphenylsulfone.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1971, Volume: 4, Issue:2

    Topics: Animals; Antimalarials; Chemical Phenomena; Chemistry; Dapsone; Injections; Injections, Intraperiton

1971
Partial reversal of the in vivo antimalarial activity of DDS against Plasmodium berghei by induced hyperglycemia.
    The American journal of tropical medicine and hygiene, 1971, Volume: 20, Issue:4

    Topics: Administration, Oral; Alloxan; Animals; Antimalarials; Blood Glucose; Dapsone; Erythrocytes; Glucose

1971
Resistant malaria.
    British medical journal, 1971, Apr-24, Volume: 2, Issue:5755

    Topics: Child; Dapsone; Drug Resistance, Microbial; Drug Synergism; Humans; Malaria; Pyrimethamine; Pyrimidi

1971
Medical problems from Vietnam.
    Annals of internal medicine, 1968, Volume: 69, Issue:1

    Topics: Dapsone; Humans; Malaria; Military Medicine; Pyrimethamine; Quinine; Vietnam

1968
Methemoglobinemia provoked by malarial chemoprophylaxis in Vietnam.
    The New England journal of medicine, 1968, Nov-21, Volume: 279, Issue:21

    Topics: Antimalarials; Chloroquine; Cyanosis; Dapsone; Diseases in Twins; Erythrocytes; Female; Hematocrit;

1968
Characteristics and cross-resistance patterns of chloroquine-resistant Plasmodium berghei infections in mice.
    Experimental parasitology, 1968, Volume: 23, Issue:1

    Topics: Amodiaquine; Animals; Antimalarials; Chloroquine; Dapsone; Drug Resistance, Microbial; Female; Hemat

1968
Treatment of acute falciparum malaria with diaphenylsulfone in North-East Tanzania.
    The Journal of tropical medicine and hygiene, 1965, Volume: 68, Issue:10

    Topics: Africa, Eastern; Dapsone; Humans; Malaria

1965
Drug resistance in Plasmodium berghei Vincke and Lips, 1948. II. Triazine resistance.
    Experimental parasitology, 1965, Volume: 17, Issue:1

    Topics: Animals; Dapsone; In Vitro Techniques; Malaria; Mice; Plasmodium; Primaquine; Proguanil; Pyrimethami

1965
Drug resistance in Plasmodium berghei Vincke and Lips, 1948. I. Chloroquine resistance.
    Experimental parasitology, 1965, Volume: 17, Issue:1

    Topics: Amodiaquine; Animals; Chloroquine; Dapsone; Malaria; Mice; Plasmodium; Primaquine; Proguanil; Pyrime

1965
Drug resistance in Plasmodium berghei Vincke and Lips, 1948. 3. Multiple drug resistance.
    Experimental parasitology, 1965, Volume: 17, Issue:1

    Topics: Animals; Antimalarials; Dapsone; In Vitro Techniques; Malaria; Mice; Plasmodium; Quinacrine; Sulfadi

1965