Page last updated: 2024-10-25

dapsone and Inflammation

dapsone has been researched along with Inflammation in 21 studies

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"Dapsone exerts cardioprotective effects on doxorubicin-induced cardiotoxicity through its anti-inflammatory and antioxidant mechanism."7.96Cardioprotective effects of dapsone against doxorubicin-induced cardiotoxicity in rats. ( Dehpour, AR; Emami, AH; Faghir-Ghanesefat, H; Nezamoleslami, S; Sheibani, M, 2020)
"Phenotypic activity of these two routes of metabolism was assessed in 18 patients receiving longterm dapsone therapy for inflammatory dermatoses and was related to the development of dapsone toxicity."7.70Development of dapsone toxicity in patients with inflammatory dermatoses: activity of acetylation and hydroxylation of dapsone as risk factors. ( Adedoyin, A; Bluhm, RE; Branch, RA; McCarver, DG, 1999)
"

BACKGROUND: Acne vulgaris has varying physical and psychological effects in men and women of different ages, races, and ethnicities."

6.84Treatment Response With Once-Daily Topical Dapsone Gel, 7.5% for Acne Vulgaris: Subgroup Analysis of Pooled Data from Two Randomized, Double-Blind Stu. ( Berk, DR; Bruce, S; Chang-Lin, JE; Downie, J; Draelos, ZD; Kaoukhov, A; Kempers, SE; Peredo, MI; Rodriguez, DA; Ruan, S, 2017)
"Treatment with dapsone and metformin reversed the effects of testosterone in the DAP and MET groups."5.62The effect of dapsone in testosterone enanthate-induced polycystic ovary syndrome in rat. ( Dehpour, AR; Khaledi, E; Khazaei, M; Noori, T; Sadeghi, F; Shirooie, S; Sobarzo-Sánchez, E, 2021)
"Dapsone has been shown to possess anti-inflammatory activity in a variety of animal models."5.26The anti-inflammatory profile of dapsone in animal models of inflammation. ( Gemmell, DK; Lewis, AJ; Stimson, WH, 1978)
"Dapsone exerts cardioprotective effects on doxorubicin-induced cardiotoxicity through its anti-inflammatory and antioxidant mechanism."3.96Cardioprotective effects of dapsone against doxorubicin-induced cardiotoxicity in rats. ( Dehpour, AR; Emami, AH; Faghir-Ghanesefat, H; Nezamoleslami, S; Sheibani, M, 2020)
"Phenotypic activity of these two routes of metabolism was assessed in 18 patients receiving longterm dapsone therapy for inflammatory dermatoses and was related to the development of dapsone toxicity."3.70Development of dapsone toxicity in patients with inflammatory dermatoses: activity of acetylation and hydroxylation of dapsone as risk factors. ( Adedoyin, A; Bluhm, RE; Branch, RA; McCarver, DG, 1999)
"

BACKGROUND: Acne vulgaris has varying physical and psychological effects in men and women of different ages, races, and ethnicities."

2.84Treatment Response With Once-Daily Topical Dapsone Gel, 7.5% for Acne Vulgaris: Subgroup Analysis of Pooled Data from Two Randomized, Double-Blind Stu. ( Berk, DR; Bruce, S; Chang-Lin, JE; Downie, J; Draelos, ZD; Kaoukhov, A; Kempers, SE; Peredo, MI; Rodriguez, DA; Ruan, S, 2017)
"Recognition that acne is an inflammatory condition, not an infectious one, has led to a call for reduction in antibiotic use."2.61An Overview of Acne Therapy, Part 1: Topical therapy, Oral Antibiotics, Laser and Light Therapy, and Dietary Interventions. ( Baldwin, HE; Marson, JW, 2019)
"Treatment with dapsone and metformin reversed the effects of testosterone in the DAP and MET groups."1.62The effect of dapsone in testosterone enanthate-induced polycystic ovary syndrome in rat. ( Dehpour, AR; Khaledi, E; Khazaei, M; Noori, T; Sadeghi, F; Shirooie, S; Sobarzo-Sánchez, E, 2021)
"Acute myeloid leukemia was the most common malignancy (in 24 of 83 patients [29%])."1.48Sweet syndrome in patients with and without malignancy: A retrospective analysis of 83 patients from a tertiary academic referral center. ( Ashchyan, HJ; Gowda, A; James, WD; McMahon, CM; Micheletti, RG; Nelson, CA; Noe, MH; Perl, AE; Rosenbach, M; Wu, B, 2018)
" dapsone, nimesulide and sulphapyridine, have the potential to reduce the bioavailability of neutrophil-derived HOCl and, in turn, to favour the alpha 1-antitrypsin-dependent control of neutrophil elastolytic activity."1.29Sulphonamides as anti-inflammatory agents: old drugs for new therapeutic strategies in neutrophilic inflammation? ( Balbi, A; Bevilacqua, M; Dallegri, F; Dapino, P; Ottonello, L; Scirocco, MC, 1995)
"Dapsone has been examined by two established animal anti-inflammatory models and found to possess anti-inflammatory activity comparable with established non-steroidal anti-inflammatory drugs."1.26Anti-inflammatory actions of dapsone and its related biochemistry. ( Best, R; Capstick, RB; Lewis, DA; Williams, K, 1976)
"Dapsone has been shown to possess anti-inflammatory activity in a variety of animal models."1.26The anti-inflammatory profile of dapsone in animal models of inflammation. ( Gemmell, DK; Lewis, AJ; Stimson, WH, 1978)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19907 (33.33)18.7374
1990's3 (14.29)18.2507
2000's1 (4.76)29.6817
2010's8 (38.10)24.3611
2020's2 (9.52)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Galijasevic, S1
McLarnon, JG1
Sheibani, M1
Nezamoleslami, S1
Faghir-Ghanesefat, H1
Emami, AH1
Dehpour, AR2
Shirooie, S1
Khaledi, E1
Noori, T1
Khazaei, M1
Sadeghi, F1
Sobarzo-Sánchez, E1
Draelos, ZD1
Rodriguez, DA1
Kempers, SE1
Bruce, S1
Peredo, MI1
Downie, J1
Chang-Lin, JE1
Berk, DR1
Ruan, S1
Kaoukhov, A1
Nelson, CA1
Noe, MH1
McMahon, CM1
Gowda, A1
Wu, B1
Ashchyan, HJ1
Perl, AE1
James, WD1
Micheletti, RG1
Rosenbach, M1
Geyfman, M1
Debabov, D1
Poloso, N1
Alvandi, N1
Marson, JW1
Baldwin, HE1
Bhat, YJ1
Hassan, I1
Sajad, P1
Akhtar, S1
Sheikh, S1
Chawla, S1
Smart, CJ1
Moots, RJ1
Davies, P1
Bonney, RJ1
Humes, JL1
Kuehl, FA1
Guill, MA1
Aton, JK1
Ottonello, L1
Dapino, P1
Scirocco, MC1
Balbi, A1
Bevilacqua, M1
Dallegri, F1
Cairns, BA1
Herbst, CA1
Sartor, BR1
Briggaman, RA1
Koruda, MJ1
Bluhm, RE1
Adedoyin, A1
McCarver, DG1
Branch, RA1
Williams, K1
Capstick, RB1
Lewis, DA1
Best, R1
Lewis, AJ2
Gemmell, DK2
Stimson, WH2
Jampol, LM1
West, C1
Goldberg, MF1
Maloff, BL1
Fox, D1
Bruin, E1
Di Meo, TM1

Reviews

4 reviews available for dapsone and Inflammation

ArticleYear
The development of myeloperoxidase inhibitors.
    Bioorganic & medicinal chemistry letters, 2019, 01-01, Volume: 29, Issue:1

    Topics: Animals; Enzyme Inhibitors; Humans; Inflammation; Molecular Structure; Monocytes; Neutrophils; Perox

2019
Consideration of a Pharmacological Combinatorial Approach to Inhibit Chronic Inflammation in Alzheimer's Disease.
    Current Alzheimer research, 2019, Volume: 16, Issue:11

    Topics: Alzheimer Disease; Animals; Dapsone; Drug Therapy, Combination; Humans; Ibuprofen; Inflammation; Min

2019
An Overview of Acne Therapy, Part 1: Topical therapy, Oral Antibiotics, Laser and Light Therapy, and Dietary Interventions.
    Dermatologic clinics, 2019, Volume: 37, Issue:2

    Topics: Acne Vulgaris; Administration, Cutaneous; Administration, Oral; Anti-Bacterial Agents; Combined Moda

2019
Peristomal pyoderma gangrenosum and inflammatory bowel disease.
    Archives of surgery (Chicago, Ill. : 1960), 1994, Volume: 129, Issue:7

    Topics: Adolescent; Adult; Biopsy; Colostomy; Crohn Disease; Dapsone; Female; Humans; Ileostomy; Inflammatio

1994

Trials

1 trial available for dapsone and Inflammation

ArticleYear
Treatment Response With Once-Daily Topical Dapsone Gel, 7.5% for Acne Vulgaris: Subgroup Analysis of Pooled Data from Two Randomized, Double-Blind Stu.
    Journal of drugs in dermatology : JDD, 2017, Jun-01, Volume: 16, Issue:6

    Topics: Acne Vulgaris; Administration, Topical; Adolescent; Age Factors; Child; Dapsone; Dermatologic Agents

2017

Other Studies

16 other studies available for dapsone and Inflammation

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Cardioprotective effects of dapsone against doxorubicin-induced cardiotoxicity in rats.
    Cancer chemotherapy and pharmacology, 2020, Volume: 85, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Cardiotoxicity; Cytokines; Dapsone; Doxo

2020
The effect of dapsone in testosterone enanthate-induced polycystic ovary syndrome in rat.
    The Journal of steroid biochemistry and molecular biology, 2021, Volume: 214

    Topics: Androgens; Animals; Cytokines; Dapsone; Female; Inflammation; Metformin; Ovary; Polycystic Ovary Syn

2021
Sweet syndrome in patients with and without malignancy: A retrospective analysis of 83 patients from a tertiary academic referral center.
    Journal of the American Academy of Dermatology, 2018, Volume: 78, Issue:2

    Topics: Academic Medical Centers; Adrenal Cortex Hormones; Adult; Aged; Anemia; Arthralgia; Colchicine; Daps

2018
Mechanistic insight into the activity of a sulfone compound dapsone on Propionibacterium (Newly Reclassified as Cutibacterium) Acnes-mediated cytokine production.
    Experimental dermatology, 2019, Volume: 28, Issue:2

    Topics: Acne Vulgaris; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Cell Prolifer

2019
Sweet's Syndrome: An Evidence-Based Report.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2015, Volume: 25, Issue:7

    Topics: Adrenal Cortex Hormones; Adult; Anti-Infective Agents; Dapsone; Female; Humans; Inflammation; Leukoc

2015
Recto-vaginal fistula: a refractory complication of Behcet's disease.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2007, Volume: 9, Issue:7

    Topics: Adult; Antibodies, Monoclonal; Behcet Syndrome; Dapsone; Disease Progression; Female; Humans; Inflam

2007
The role of macrophage secretory products in chronic inflammatory processes.
    The Journal of investigative dermatology, 1980, Volume: 74, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acids; Cell Division; Complement System Proteins; Dap

1980
Facial granuloma responsive to dapsone therapy.
    Archives of dermatology, 1982, Volume: 118, Issue:5

    Topics: Adult; Dapsone; Facial Dermatoses; Female; Granuloma; Humans; Inflammation

1982
Sulphonamides as anti-inflammatory agents: old drugs for new therapeutic strategies in neutrophilic inflammation?
    Clinical science (London, England : 1979), 1995, Volume: 88, Issue:3

    Topics: alpha 1-Antitrypsin; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultu

1995
Development of dapsone toxicity in patients with inflammatory dermatoses: activity of acetylation and hydroxylation of dapsone as risk factors.
    Clinical pharmacology and therapeutics, 1999, Volume: 65, Issue:6

    Topics: Acetylation; Adult; Anti-Inflammatory Agents, Non-Steroidal; Dapsone; Female; Gangrene; Humans; Hydr

1999
Anti-inflammatory actions of dapsone and its related biochemistry.
    The Journal of pharmacy and pharmacology, 1976, Volume: 28, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Dapsone; Erythrocytes; Female; Guinea Pigs; In Vitro T

1976
The anti-inflammatory profile of dapsone in animal models of inflammation.
    Agents and actions, 1978, Volume: 8, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental;

1978
Studies on the anti-inflammatory properties of dapsone in a variety of animal models [proceedings].
    British journal of pharmacology, 1977, Volume: 61, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Dapsone; Female; Guinea Pigs; Inflammation; Male; Rats; Rats, Inb

1977
Therapy of scleritis with cytotoxic agents.
    American journal of ophthalmology, 1978, Volume: 86, Issue:2

    Topics: Adult; Antineoplastic Agents; Cyclophosphamide; Dapsone; Drug Therapy, Combination; Eye Diseases; Fe

1978
Dapsone inhibits LTB4 binding and bioresponse at the cellular and physiologic levels.
    European journal of pharmacology, 1988, Dec-06, Volume: 158, Issue:1-2

    Topics: Animals; Chemotaxis, Leukocyte; Dapsone; Female; Humans; In Vitro Techniques; Inflammation; Leukotri

1988