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dapsone and Infection, Toxoplasma gondii

dapsone has been researched along with Infection, Toxoplasma gondii in 20 studies

Research Excerpts

ExcerptRelevanceReference
"Dapsone alone was not as good as either of the other two drugs tested."5.24Sulphadimidine, pyrimethamine and dapsone in the treatment of toxoplasmosis in mice. ( BEVERLEY, JK; FRY, BA, 1957)
" For dapsone, among 100 patients given 100 mg daily instead of twice a week for 1 year (primary prophylaxis), seven fewer patients would develop P carinii pneumonia, but 17 more would have significant toxic reactions."4.79A meta-analysis of the relative efficacy and toxicity of Pneumocystis carinii prophylactic regimens. ( Cappelleri, JC; Ioannidis, JP; Lau, J; Sacks, HS; Skolnik, PR, 1996)
"In a meta-analysis, we examined the efficacy of aerosolized pentamidine, trimethoprim-sulfamethoxazole, and dapsone or dapsone/pyrimethamine for the prevention of Pneumocystis carinii pneumonia and toxoplasma encephalitis in patients with HIV infection."4.79Meta-analysis of prophylactic treatments against Pneumocystis carinii pneumonia and toxoplasma encephalitis in HIV-infected patients. ( Bucher, HC; Griffith, L; Guyatt, GH; Opravil, M, 1997)
" Overall results from these studies indicate patients who are eligible for PCP prophylaxis should be advised to take double-strength trimethoprim/sulfamethoxazole (TMP/SMX) on a daily basis, a dosage found more effective than thrice-weekly."1.30Optimizing PCP therapy. ( Cadman, J; Torres, G, 1997)
" Within a short time of dosing such animals, there is little or none of the uncombined drug in the blood."1.24The treatment of experimental toxoplasmosis in rabbits. ( BEVERLEY, JK; FRY, BA, 1957)
"Dapsone alone was not as good as either of the other two drugs tested."1.24Sulphadimidine, pyrimethamine and dapsone in the treatment of toxoplasmosis in mice. ( BEVERLEY, JK; FRY, BA, 1957)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19906 (30.00)18.7374
1990's13 (65.00)18.2507
2000's0 (0.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wozel, VE1
BEVERLEY, JK2
FRY, BA2
GARIN, JP1
POTTON, F1
CROSS, JB2
Podzamczer, D2
Salazar, A1
Jiménez, J2
Consiglio, E1
Santín, M2
Casanova, A2
Rufí, G1
Gudiol, F1
Oksenhendler, E1
Charreau, I1
Tournerie, C1
Azihary, M1
Carbon, C1
Aboulker, JP1
Bolao, F1
Gudiol, GR1
Opravil, M2
Keusch, G1
Lüthy, R1
Ioannidis, JP1
Cappelleri, JC1
Skolnik, PR1
Lau, J1
Sacks, HS1
Bucher, HC1
Griffith, L1
Guyatt, GH1
Sackoff, J1
McFarland, J1
Su, S1
Bryan, E1
Payen, MC1
De Wit, S1
Sommereijns, B1
Clumeck, N1
Cheng, B1
Torres, G1
Cadman, J1
Hardy, WD2
Clotet, B1
Sirera, G1
Romeu, J1
Gimeno, JM1
Jou, A1
Condom, MJ1
Tor, J1
Foz, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Fluconazole, Clarithromycin, and Rifabutin on the Pharmacokinetics of Sulfamethoxazole and Dapsone and Their Hydroxylamine Metabolites[NCT00000826]Phase 148 participants InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for dapsone and Infection, Toxoplasma gondii

ArticleYear
A meta-analysis of the relative efficacy and toxicity of Pneumocystis carinii prophylactic regimens.
    Archives of internal medicine, 1996, Jan-22, Volume: 156, Issue:2

    Topics: AIDS-Related Opportunistic Infections; Dapsone; Dose-Response Relationship, Drug; Humans; Logistic M

1996
Meta-analysis of prophylactic treatments against Pneumocystis carinii pneumonia and toxoplasma encephalitis in HIV-infected patients.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1997, Jun-01, Volume: 15, Issue:2

    Topics: Administration, Inhalation; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Antifungal

1997
Prophylaxis of AIDS-related opportunistic infections (OIs). Current status and future strategies.
    AIDS clinical review, 1991

    Topics: Acquired Immunodeficiency Syndrome; Aerosols; Animals; Cryptococcosis; Cytomegalovirus Infections; D

1991
Prophylaxis of AIDS-related opportunistic infections (OIs).
    AIDS clinical review, 1989

    Topics: Acquired Immunodeficiency Syndrome; Cryptococcosis; Cytomegalovirus Infections; Dapsone; Drug Combin

1989

Trials

5 trials available for dapsone and Infection, Toxoplasma gondii

ArticleYear
Intermittent trimethoprim-sulfamethoxazole compared with dapsone-pyrimethamine for the simultaneous primary prophylaxis of Pneumocystis pneumonia and toxoplasmosis in patients infected with HIV.
    Annals of internal medicine, 1995, May-15, Volume: 122, Issue:10

    Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Dapsone; Drug Administration Schedule; Drug Ther

1995
Thrice-weekly cotrimoxazole is better than weekly dapsone-pyrimethamine for the primary prevention of Pneumocystis carinii pneumonia in HIV-infected patients.
    AIDS (London, England), 1993, Volume: 7, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Dapsone; Drug Administration Schedule; Drug Therapy, C

1993
Prophylaxis for opportunistic infections among HIV-infected patients receiving medical care.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, Dec-01, Volume: 19, Issue:4

    Topics: Adolescent; Adult; AIDS-Related Opportunistic Infections; Analysis of Variance; Anti-Infective Agent

1998
A controlled trial of dapsone versus pyrimethamine-sulfadoxine for primary prophylaxis of Pneumocystis carinii pneumonia and toxoplasmosis in patients with AIDS.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1997, Volume: 51, Issue:10

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; AIDS-Related Opportunistic Infections; Anti-Infecti

1997
Prophylaxis of AIDS-related opportunistic infections (OIs). Current status and future strategies.
    AIDS clinical review, 1991

    Topics: Acquired Immunodeficiency Syndrome; Aerosols; Animals; Cryptococcosis; Cytomegalovirus Infections; D

1991

Other Studies

12 other studies available for dapsone and Infection, Toxoplasma gondii

ArticleYear
Innovative use of dapsone.
    Dermatologic clinics, 2010, Volume: 28, Issue:3

    Topics: Adult; Anti-Infective Agents; Autoimmune Diseases; Child; Dapsone; Humans; Hypersensitivity; Jaundic

2010
The treatment of experimental toxoplasmosis in rabbits.
    British journal of pharmacology and chemotherapy, 1957, Volume: 12, Issue:2

    Topics: Animals; Antimalarials; Dapsone; Pyrimethamine; Rabbits; Sulfamethazine; Sulfanilamide; Sulfanilamid

1957
Sulphadimidine, pyrimethamine and dapsone in the treatment of toxoplasmosis in mice.
    British journal of pharmacology and chemotherapy, 1957, Volume: 12, Issue:2

    Topics: Animals; Antimalarials; Dapsone; Drug Therapy, Combination; Mice; Pyrimethamine; Sulfamethazine; Sul

1957
[Hepatic lesions in experimental toxoplasmosis in mice: fatal acute form and chronic form treated by diaminodiphenylsulfone].
    Revue internationale d'hepatologie, 1954, Volume: 4, Issue:4-5

    Topics: Animals; Dapsone; Liver; Mice; Sulfones; Toxoplasmosis

1954
Diasone and promin as therapeutic agents in experimental toxoplasmosis.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1951, Volume: 76, Issue:3

    Topics: Dapsone; Humans; Sulfones; Toxoplasmosis

1951
Diasone, avlosulfon and sulphetrone as therapeutic agents in experimental toxoplasmosis.
    The American journal of tropical medicine and hygiene, 1952, Volume: 1, Issue:4

    Topics: Dapsone; Humans; Sulfones; Toxoplasmosis

1952
Drugs for AIDS and associated infections.
    The Medical letter on drugs and therapeutics, 1995, Oct-13, Volume: 37, Issue:959

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Amphotericin B; Antifunga

1995
Toxoplasma gondii infection in advanced HIV infection.
    AIDS (London, England), 1994, Volume: 8, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Dapsone; Encephalitis; Female; Humans; Male; Middle Ag

1994
Pyrimethamine inhibits renal secretion of creatinine.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:5

    Topics: Adult; Creatinine; Dapsone; Drug Administration Schedule; Drug Interactions; Female; Humans; Kidney;

1993
Preventing opportunistic infections.
    PI perspective, 1995, Issue:no 16

    Topics: Acyclovir; AIDS-Related Opportunistic Infections; Clarithromycin; Clindamycin; Clinical Trials as To

1995
Optimizing PCP therapy.
    GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies, 1997, Volume: 11, Issue:10

    Topics: Aerosols; AIDS-Related Opportunistic Infections; Antifungal Agents; Atovaquone; CD4 Lymphocyte Count

1997
Twice-weekly dapsone-pyrimethamine for preventing PCP and cerebral toxoplasmosis.
    AIDS (London, England), 1991, Volume: 5, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Brain Diseases; Dapsone; Drug Administration Schedule; Drug Ther

1991