dapsone has been researched along with Infarction, Middle Cerebral Artery in 2 studies
Infarction, Middle Cerebral Artery: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Male adult Wistar rats were subjected to middle cerebral artery occlusion (MCAO) for 90 min followed by 24 h of ischemic reperfusion (I/R)." | 1.56 | Dapsone prolong delayed excitotoxic neuronal cell death by interacting with proapoptotic/survival signaling proteins. ( Gakare, S; Kumar, R; Mahale, A; Prakash, A; Sarode, LP; Ugale, RR, 2020) |
| "Dapsone-treated animals showed a reduction of 93% (9." | 1.32 | Neuroprotective effect of dapsone in an occlusive model of focal ischemia in rats. ( Nader-Kawachi, J; Nava-Ruiz, C; Ríos, C; Rodriguez-Payán, AJ, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mahale, A | 1 |
| Kumar, R | 1 |
| Sarode, LP | 1 |
| Gakare, S | 1 |
| Prakash, A | 1 |
| Ugale, RR | 1 |
| Ríos, C | 1 |
| Nader-Kawachi, J | 1 |
| Rodriguez-Payán, AJ | 1 |
| Nava-Ruiz, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Neuroprotective Effect of Dapsone in Patients With Aneurysmal Subarachnoid Hemorrhage: Prospective, Randomized, Double-Blinded, Placebo-Controlled, Clinical Trial[NCT05131295] | Phase 3 | 49 participants (Actual) | Interventional | 2007-09-05 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for dapsone and Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Dapsone prolong delayed excitotoxic neuronal cell death by interacting with proapoptotic/survival signaling proteins.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Brain; Cells, Cultured; Dapsone; Disease Models, | 2020 |
Neuroprotective effect of dapsone in an occlusive model of focal ischemia in rats.
Topics: Animals; Brain Infarction; Brain Ischemia; Dapsone; Disease Models, Animal; Dose-Response Relationsh | 2004 |