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dapsone and IgA Vasculitis

dapsone has been researched along with IgA Vasculitis in 24 studies

IgA Vasculitis: A systemic non-thrombocytopenic purpura caused by HYPERSENSITIVITY VASCULITIS and deposition of IGA-containing IMMUNE COMPLEXES within the blood vessels throughout the body, including those in the kidney (KIDNEY GLOMERULUS). Clinical symptoms include URTICARIA; ERYTHEMA; ARTHRITIS; GASTROINTESTINAL HEMORRHAGE; and renal involvement. Most cases are seen in children after acute upper respiratory infections.

Research Excerpts

ExcerptRelevanceReference
" In chronic cutaneous manifestations of IgA vasculitis, dapsone seems to show a good effectiveness."9.01Indications and efficiency of dapsone in IgA vasculitis (Henoch-Schonlein purpura): case series and a review of the literature. ( Dima, B; Gilliaux, O; Muyshont, L; Roman, C; Schurmans, T, 2019)
" In chronic cutaneous manifestations of IgA vasculitis, dapsone seems to show a good effectiveness."5.01Indications and efficiency of dapsone in IgA vasculitis (Henoch-Schonlein purpura): case series and a review of the literature. ( Dima, B; Gilliaux, O; Muyshont, L; Roman, C; Schurmans, T, 2019)
"Dapsone therapy for leukocytoclastic (necrotizing) vasculitis has been little used, except for the variant forms of erythema elevatum diutinum and urticarial vasculitis."3.67Sulfone therapy in the treatment of leukocytoclastic vasculitis. Report of three cases. ( Fredenberg, MF; Malkinson, FD, 1987)
"Haemorrhagic bullous lesions are a recognized but rare occurrence with HSP in children."2.45Management of haemorrhagic bullous lesions in Henoch-Schonlein purpura: is there any consensus? ( Kausar, S; Yalamanchili, A, 2009)
"Dapsone was introduced when skin lesions were recurrent, extensive, and persistent, due to its known ability to act as an anti-IgA and as an anticytotoxic agent against polynuclear neutrophils."1.37[Dapsone for chronic skin lesions in 3 children suffering from Henoch-Schönlein vasculitis]. ( Fischbach, M; Lipsker, D; Mazille, N, 2011)
"Dapsone is a sulfone essentially used to treat leprae."1.34[Dapsone: an opportunity to spare corticoid use for Henoch-Schönlein treatment? A case report]. ( Bovy, C; Krzesinski, JM; Parotte, MC, 2007)
" Therefore dapsone therapy was initiated at a dosage of 100 mg daily after checking the glucose-6-phosphate-dehydrogenase and with regular control of the blood methemoglobin level."1.30[Henoch-Schönlein purpura: successful treatment with Dapsone]. ( Abeck, D; Albrecht, J; Hein, R; Mempel, M; Ring, J, 1999)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19904 (16.67)18.7374
1990's4 (16.67)18.2507
2000's6 (25.00)29.6817
2010's9 (37.50)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Yoshida, M1
Nambu, R1
Yasuda, R1
Sakaguchi, H1
Hara, T1
Iwama, I1
Mizuochi, T1
Ramelli, V1
Rinoldi, PO1
Bianchetti, MG2
Lava, SAG1
Ramelli, GP2
Milani, GP1
Lee, KH1
Park, JH1
Kim, DH1
Hwang, J1
Lee, G1
Hyun, JS1
Heo, ST1
Choi, JH1
Kim, M2
Kim, SI1
Eisenhut, M1
Kronbichler, A1
Shin, JI2
Volejnikova, J1
Horacek, J1
Kopriva, F1
Roman, C1
Dima, B1
Muyshont, L1
Schurmans, T1
Gilliaux, O1
Bech, AP1
Reichert, LJ1
Cohen Tervaert, JW1
Chen, CB1
Garlapati, S1
Lancaster, JD1
Zinn, Z1
Bacaj, P1
Patra, KP1
Kausar, S1
Yalamanchili, A1
Sakanoue, M1
Higashi, Y1
Kawai, K2
Sugita, S1
Kanekura, T1
Mazille, N1
Lipsker, D1
Fischbach, M1
Hirahara, K1
Kano, Y1
Asano, Y1
Shiohara, T1
Shimomura, N1
Watanabe, S1
Katsuumi, K1
Ito, M1
Iqbal, H1
Evans, A1
Lee, JS1
Chung, KS1
Parotte, MC1
Bovy, C1
Krzesinski, JM1
Ledermann, JA1
Hoffbrand, BI2
Sarma, PS1
Albrecht, J1
Mempel, M1
Hein, R1
Abeck, D1
Ring, J1
Saulsbury, FT1
Hart, MH1
Vesole, DH1
Chamouard, P1
Baumann, R1
Thomas, G1
Weill, JP1
Fredenberg, MF1
Malkinson, FD1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Neuroprotective Effect of Dapsone in Patients With Aneurysmal Subarachnoid Hemorrhage: Prospective, Randomized, Double-Blinded, Placebo-Controlled, Clinical Trial[NCT05131295]Phase 349 participants (Actual)Interventional2007-09-05Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for dapsone and IgA Vasculitis

ArticleYear
Indications and efficiency of dapsone in IgA vasculitis (Henoch-Schonlein purpura): case series and a review of the literature.
    European journal of pediatrics, 2019, Volume: 178, Issue:8

    Topics: Child, Preschool; Chronic Disease; Dapsone; Female; Folic Acid Antagonists; Humans; IgA Vasculitis;

2019
Management of haemorrhagic bullous lesions in Henoch-Schonlein purpura: is there any consensus?
    The Journal of dermatological treatment, 2009, Volume: 20, Issue:2

    Topics: Adrenal Cortex Hormones; Blister; Child; Combined Modality Therapy; Dapsone; Disease Progression; Dr

2009

Other Studies

22 other studies available for dapsone and IgA Vasculitis

ArticleYear
Dapsone for Refractory Gastrointestinal Symptoms in Children With Immunoglobulin A Vasculitis.
    Pediatrics, 2022, 09-01, Volume: 150, Issue:3

    Topics: Abdominal Pain; Adrenal Cortex Hormones; Child; Dapsone; Gastrointestinal Diseases; Humans; IgA Vasc

2022
Dapsone in immunoglobulin A-associated vasculitis.
    European journal of pediatrics, 2019, Volume: 178, Issue:12

    Topics: Dapsone; Humans; IgA Vasculitis; Immunoglobulin A; Vasculitis; Vasculitis, Leukocytoclastic, Cutaneo

2019
Dapsone as a potential treatment option for Henoch-Schönlein Purpura (HSP).
    Medical hypotheses, 2017, Volume: 108

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Chemotaxis; Cytokines; Dapsone; Free Radicals; Hu

2017
Dapsone treatment is efficient against persistent cutaneous and gastrointestinal symptoms in children with Henoch-Schönlein purpura.
    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2018, Volume: 162, Issue:2

    Topics: Adolescent; Child; Child, Preschool; Chlamydophila Infections; Chlamydophila pneumoniae; Dapsone; Ga

2018
Dapsone for the treatment of chronic IgA vasculitis (Henoch-Schonlein).
    The Netherlands journal of medicine, 2013, Volume: 71, Issue:4

    Topics: Anti-Infective Agents; Biopsy; Dapsone; Diagnosis, Differential; Female; Humans; IgA Vasculitis; Ski

2013
Bullous Henoch-Schönlein purpura in children.
    Cutis, 2015, Volume: 96, Issue:4

    Topics: Abdominal Pain; Adolescent; Dapsone; Dermatologic Agents; Female; Follow-Up Studies; Glucocorticoids

2015
Henoch-Schönlein purpura with epididymitis in an adult.
    The Journal of dermatology, 2011, Volume: 38, Issue:6

    Topics: Adult; Dapsone; Epididymitis; Humans; IgA Vasculitis; Male; Prednisolone

2011
[Dapsone for chronic skin lesions in 3 children suffering from Henoch-Schönlein vasculitis].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2011, Volume: 18, Issue:11

    Topics: Adolescent; Dapsone; Female; Humans; IgA Vasculitis; Male; Skin Diseases

2011
Osteonecrosis of the femoral head in a patient with Henoch-Schönlein purpura and drug-induced hypersensitivity syndrome treated with corticosteroids.
    Acta dermato-venereologica, 2013, Volume: 93, Issue:1

    Topics: Adult; Anti-Infective Agents; Dapsone; Eosinophilia; Erythema; Exanthema; Femur Head Necrosis; Fever

2013
Adult Henoch-Schönlein purpura with severe abdominal pain treated with dapsone and factor XIII concentrate.
    The Journal of dermatology, 2005, Volume: 32, Issue:2

    Topics: Abdominal Pain; Adult; Anti-Inflammatory Agents, Non-Steroidal; Dapsone; Diagnosis, Differential; Dr

2005
Dapsone therapy for Henoch-Schönlein purpura: a case series.
    Archives of disease in childhood, 2005, Volume: 90, Issue:9

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Dapsone; Female; Humans; IgA Vascu

2005
Dapsone therapy for Henoch-Schonlein purpura.
    Archives of disease in childhood, 2006, Volume: 91, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Dapsone; Female; Humans; IgA Vascu

2006
[Dapsone: an opportunity to spare corticoid use for Henoch-Schönlein treatment? A case report].
    Revue medicale de Liege, 2007, Volume: 62, Issue:12

    Topics: Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents; Dapsone; Drug Resistance; Drug Therapy, Co

2007
Dapsone in allergic vasculitis: its use in Henoch-Schönlein disease following vaccination.
    Journal of the Royal Society of Medicine, 1983, Volume: 76, Issue:7

    Topics: Adult; Chronic Disease; Dapsone; Humans; IgA Vasculitis; Male; Vaccination; Vasculitis, Leukocytocla

1983
Dapsone in Henoch-Schönlein purpura.
    Postgraduate medical journal, 1994, Volume: 70, Issue:824

    Topics: Adolescent; Adult; Dapsone; Drug Administration Schedule; Female; Humans; IgA Vasculitis; Male; Midd

1994
Dapsone in cutaneous Henoch-Schönlein syndrome--worth a trial.
    Acta paediatrica (Oslo, Norway : 1992), 1997, Volume: 86, Issue:3

    Topics: Adolescent; Dapsone; Dose-Response Relationship, Drug; Female; Humans; IgA Vasculitis; Leprostatic A

1997
[Henoch-Schönlein purpura: successful treatment with Dapsone].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1999, Volume: 50, Issue:11

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Dapsone; Follow-Up Studies; Humans; IgA Vasculitis;

1999
Crohn's disease presenting with Henoch-Schönlein purpura.
    Journal of pediatric gastroenterology and nutrition, 2000, Volume: 31, Issue:2

    Topics: Adolescent; Biopsy; Blood Vessels; Colon; Complement C3; Crohn Disease; Dapsone; Endoscopy, Gastroin

2000
Dapsone in Henoch-Schönlein purpura--worth a trial.
    Postgraduate medical journal, 1991, Volume: 67, Issue:793

    Topics: Adolescent; Adult; Aged; Dapsone; Humans; IgA Vasculitis; Male; Neutrophils

1991
Diffuse large-cell lymphoma in an adult with Schönlein-Henoch purpura.
    Archives of internal medicine, 1987, Volume: 147, Issue:11

    Topics: Chronic Disease; Dapsone; Humans; IgA Vasculitis; Immunoglobulin lambda-Chains; Immunoglobulin M; Ly

1987
[Value of dapsone in the treatment of digestive manifestations of rheumatoid purpura in adults].
    Annales de medecine interne, 1987, Volume: 138, Issue:8

    Topics: Aged; Dapsone; Humans; IgA Vasculitis; Intestinal Diseases; Male; Stomach Diseases

1987
Sulfone therapy in the treatment of leukocytoclastic vasculitis. Report of three cases.
    Journal of the American Academy of Dermatology, 1987, Volume: 16, Issue:4

    Topics: Adolescent; Blood Vessels; Dapsone; Female; Humans; IgA Vasculitis; Middle Aged; Skin; Vasculitis

1987