Page last updated: 2024-10-25

dapsone and Hematologic Diseases

dapsone has been researched along with Hematologic Diseases in 12 studies

Hematologic Diseases: Disorders of the blood and blood forming tissues.

Research Excerpts

ExcerptRelevanceReference
"There are no published haematological data on the long-term (more than one year) use of dapsone-pyrimethamine (Maloprim, Folaprim; one tablet a week) for malarial prophylaxis."7.67Haematological safety of long-term malarial prophylaxis with dapsone-pyrimethamine. ( Cook, IF; Kish, MY, 1985)
"There are no published haematological data on the long-term (more than one year) use of dapsone-pyrimethamine (Maloprim, Folaprim; one tablet a week) for malarial prophylaxis."3.67Haematological safety of long-term malarial prophylaxis with dapsone-pyrimethamine. ( Cook, IF; Kish, MY, 1985)
"In 1964, Sweet described an acute febrile neutrophilic dermatosis."2.43From acute febrile neutrophilic dermatosis to neutrophilic disease: forty years of clinical research. ( Vignon-Pennamen, MD; Wallach, D, 2006)
"Dapsone has been the mainstay for the treatment of leprosy since its discovery in the 1940s."1.56Hematological alterations in lepromatous leprosy: A cross-sectional observational study. ( Awan, KH; Chaudhary, M; Gupta, B; Gupta, S; Patil, S; Raj, AT, 2020)
" Dosage data indicated that fatalities had taken higher doses and continued prophylaxis after onset of symptoms."1.28Serious adverse drug reactions to pyrimethamine-sulphadoxine, pyrimethamine-dapsone and to amodiaquine in Britain. ( Phillips-Howard, PA; West, LJ, 1990)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's5 (41.67)18.2507
2000's2 (16.67)29.6817
2010's1 (8.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Gupta, B1
Gupta, S1
Chaudhary, M1
Raj, AT1
Awan, KH1
Patil, S1
Watts, PJ1
Khachemoune, A1
Wallach, D1
Vignon-Pennamen, MD1
Dao, AH1
Gregory, DW1
McKee, LC1
Vage, C1
Saab, N1
Woster, PM1
Svensson, CK1
Tingle, MD1
Park, BK1
Safrin, S1
Finkelstein, DM1
Feinberg, J1
Frame, P1
Simpson, G1
Wu, A1
Cheung, T1
Soeiro, R1
Hojczyk, P1
Black, JR1
Barber, BA1
Pegram, PS1
High, KP1
Wilson, JR1
Harris, JW1
Phillips-Howard, PA1
West, LJ1
Cook, IF1
Kish, MY1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Trimethoprim / Sulfamethoxazole in the Treatment of Mild-to-Moderate PCP in Patients With AIDS[NCT00000640]Phase 3290 participants InterventionalCompleted
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for dapsone and Hematologic Diseases

ArticleYear
Subcorneal Pustular Dermatosis: A Review of 30 Years of Progress.
    American journal of clinical dermatology, 2016, Volume: 17, Issue:6

    Topics: Connective Tissue Diseases; Dapsone; Diagnosis, Differential; Glucocorticoids; Hematologic Diseases;

2016
From acute febrile neutrophilic dermatosis to neutrophilic disease: forty years of clinical research.
    Journal of the American Academy of Dermatology, 2006, Volume: 55, Issue:6

    Topics: Abscess; Anti-Inflammatory Agents; Arthritis; Case Management; Dapsone; Digestive System Diseases; F

2006

Trials

1 trial available for dapsone and Hematologic Diseases

ArticleYear
Comparison of three regimens for treatment of mild to moderate Pneumocystis carinii pneumonia in patients with AIDS. A double-blind, randomized, trial of oral trimethoprim-sulfamethoxazole, dapsone-trimethoprim, and clindamycin-primaquine. ACTG 108 Study
    Annals of internal medicine, 1996, May-01, Volume: 124, Issue:9

    Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Clindamycin; Dapsone; Double-Blind Met

1996

Other Studies

9 other studies available for dapsone and Hematologic Diseases

ArticleYear
Hematological alterations in lepromatous leprosy: A cross-sectional observational study.
    Disease-a-month : DM, 2020, Volume: 66, Issue:7

    Topics: Adult; Case-Control Studies; Cross-Sectional Studies; Dapsone; Erythrocyte Indices; Female; Hematocr

2020
French dapsone survey.
    Prescrire international, 2002, Volume: 11, Issue:62

    Topics: Chemical and Drug Induced Liver Injury; Dapsone; Drug Hypersensitivity; France; Health Care Surveys;

2002
Specific health problems of Southeast Asian refugees in middle Tennessee.
    Southern medical journal, 1984, Volume: 77, Issue:8

    Topics: Asia, Southeastern; Dapsone; Drug Therapy, Combination; Female; Hematologic Diseases; Hemoglobin E;

1984
Dapsone-induced hematologic toxicity: comparison of the methemoglobin-forming ability of hydroxylamine metabolites of dapsone in rat and human blood.
    Toxicology and applied pharmacology, 1994, Volume: 129, Issue:2

    Topics: Adult; Animals; Ascorbic Acid; Dapsone; Drug Stability; Hematologic Diseases; Humans; Male; Methemog

1994
The use of a three compartment in vitro model to investigate the role of hepatic drug metabolism in drug-induced blood dyscrasias.
    British journal of clinical pharmacology, 1993, Volume: 36, Issue:1

    Topics: Animals; Dapsone; Drug-Related Side Effects and Adverse Reactions; Erythrocyte Count; Hematologic Di

1993
Clindamycin/primaquine as prophylaxis for Pneumocystis carinii pneumonia.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1996, Volume: 23, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Antimalarials; CD4 Lymphocyte Count; Clindamyci

1996
Hematologic side-effects of dapsone.
    The Ohio State medical journal, 1977, Volume: 73, Issue:8

    Topics: Adult; Agranulocytosis; Dapsone; Female; Hematologic Diseases; Hematopoietic System; Hemolysis; Huma

1977
Serious adverse drug reactions to pyrimethamine-sulphadoxine, pyrimethamine-dapsone and to amodiaquine in Britain.
    Journal of the Royal Society of Medicine, 1990, Volume: 83, Issue:2

    Topics: Adolescent; Adult; Amodiaquine; Antimalarials; Chemical and Drug Induced Liver Injury; Child; Child,

1990
Haematological safety of long-term malarial prophylaxis with dapsone-pyrimethamine.
    The Medical journal of Australia, 1985, Aug-19, Volume: 143, Issue:4

    Topics: Adolescent; Adult; Age Factors; Antimalarials; Child; Child, Preschool; Dapsone; Drug Combinations;

1985