dapsone has been researched along with Hansen Disease in 1078 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dapsone is one of the important drugs in the treatment of leprosy." | 9.22 | Risk factors for dapsone resistance in leprosy patients: a systematic meta-analysis. ( Jiang, H; Shi, Y; Wang, C; Wang, H; Wang, Z; Wu, Z, 2022) |
| "Dapsone (DDS), Rifampicin (RIF) and Ofloxacin (OFL) are drugs recommended by the World Health Organization (WHO) for the treatment of leprosy." | 9.22 | Drug Resistance (Dapsone, Rifampicin, Ofloxacin) and Resistance-Related Gene Mutation Features in Leprosy Patients: A Systematic Review and Meta-Analysis. ( Jin, G; Li, G; Li, X; Li, Y; Shao, Y; Wei, P; Yang, J; Zhang, L, 2022) |
| "Monthly doses of rifampin, ofloxacin, and minocycline (ROM) are expected to be effective treatment for multi-bacillary leprosy." | 9.11 | Parallel assessment of 24 monthly doses of rifampin, ofloxacin, and minocycline versus two years of World Health Organization multi-drug therapy for multi-bacillary leprosy. ( Abalos, RM; Balagon, MV; Cellona, RV; Dela Cruz, EC; Fajardo, TT; Tan, EV; Villahermosa, LG; Walsh, DS; Walsh, GP, 2004) |
| "Gastrointestinal toxicity and red skin discoloration were the major side effects observed in leprosy patients undergoing long-term treatment with clofazimine (CFZ)." | 9.10 | Biochemical and hematological side effects of clofazimine in leprosy patients. ( Costa Queiroz, RH; de Souza, AM; Melchior, E; Sampaio, SV, 2002) |
| "Methaemoglobinaemia and haemolytic anaemia were the principal side-effects observed in 30 leprosy patients undergoing long-term treatment with dapsone as a single drug or as part of multidrug therapy." | 9.08 | Influence of acetylator phenotype on the haematological and biochemical effects associated with dapsone in leprosy patients. ( Carvalho, D; Gouveia, EG; Melchior, E; Queiroz, RH; Souza, AM, 1997) |
| "The cure rates of two treatment regimens in PB leprosy were compared in a prospective randomized trial: treatment U consisting of a single dose of rifampicin 40 mg/K bodyweight, and treatment A of rifampicin 1500 mg in a single dose, followed by one year of daily dapsone 100 mg." | 9.07 | A controlled therapeutic trial in paucibacillary leprosy comparing a single dose of rifampicin with a single dose of rifampicin followed by one year of daily dapsone. The Collaborative Study Group for the Treatment of Leprosy in Zaire. ( Groenen, G; Janssens, L; Kuykens, L; Mputu, LB; Pattyn, SR, 1991) |
| "The objective of the present study was to define short-course treatment regimens for PB leprosy and to compare them with the 'classical' dapsone treatment and the WHO-PB regimen." | 9.06 | Evaluation of five treatment regimens, using either dapsone monotherapy or several doses of rifampicin in the treatment of paucibacillary leprosy. ( Baquillon, G; Husser, JA; Jamet, P; Maiga, M; Pattyn, SR, 1990) |
| "In an international multicentre controlled single-blind trial of 93 previously untreated lepromatous leprosy patients the therapeutic effects of adding rifampicin, 450 mg/day orally or 1,200 mg once monthly in a single oral dose, to dapsone (50 mg/day orally) for the first 6 months of treatment were compared." | 9.05 | Once-monthly rifampicin plus daily dapsone in initial treatment of lepromatous leprosy. ( Ghosh, S; Hajra, SK; Languillon, J; McDougall, AC; Opromolla, DV; Tonello, CJ; Yawalkar, SJ, 1982) |
| "During treatment of multibacillary leprosy with the combination rifampin (RMP) 600 mg, ethionamide (ETH) 500 mg, and either dapsone (DDS) or clofazimine (CLO) 100 mg, hepatotoxicity was observed in 4." | 9.05 | Hepatotoxicity of the combination of rifampin-ethionamide in the treatment of multibacillary leprosy. ( Bourland, J; Davies, EM; Feracci, C; Grillone, S; Janssens, L; Pattyn, SR; Saylan, T, 1984) |
| "In this controlled trial in 35 patients with lepromatous leprosy the therapeutic effects of adding rifampin 450 mg daily (Regimen A) or 1200 mg once a month (Regimen B) to a standard dapsone regimen of 50 mg daily were practically identical." | 9.05 | A controlled trial to compare the therapeutic effects of dapsone in combination with daily or once-monthly rifampin in patients with lepromatous leprosy. ( McDougall, AC; Opromolla, DV; Tonello, CJ; Yawalkar, SJ, 1981) |
| "The effects of clofazimine on neutrophil activities such as random motility, migration to the leukoattractants endotoxin-activated serum and N-formyl-L-methionyl-L-leucyl-L-phenylalanine phagocytosis of Candida albicans, postphagocytic hexose-monophosphate shunt activity, and myeloperoxidase-mediated iodination and the effects of clofazimine on lymphocyte transformation to mitogens were assessed in vitro and after ingestion of the drug by normal individuals and patients with lepromatous leprosy." | 9.05 | Effects of clofazimine alone or combined with dapsone on neutrophil and lymphocyte functions in normal individuals and patients with lepromatous leprosy. ( Anderson, R; Gatner, EM; Imkamp, FM; van Rensburg, CE, 1982) |
| "A clinical trial was initiated at ALERT, Addis Ababa, Ethiopia, to study the effect of one-year supplementary treatment on the incidence of dapsone-resistant leprosy in lepromatous patients already on dapsone monotherapy." | 9.05 | Relapse rate and incidence of dapsone resistance in lepromatous leprosy patients in Addis Ababa: risk factors and effect of short-term supplementary treatment. ( Mengistu, G; Warndorff van Diepen, T, 1985) |
| "Patients with previously untreated borderline-lepromatous or fully lepromatous leprosy were treated with one of five clofazimine (B663) regimens: 1) 200 mg daily 6 days per week; 2) 100 mg three times weekly; 3) 300 mg weekly; 4) 600 mg every other week; and 5) 600 mg on 2 consecutive days every 4 weeks." | 9.04 | Spaced clofazimine therapy of lepromatous leprosy. ( , 1976) |
| "Patients with borderline-lepromatous (BL) or fully lepromatous (LL) leprosy were treated in the sanitarium for approximately 1 year with oral rifampin (600 mg daily) or with oral dapsone (100 mg daily)." | 9.04 | Rifampin therapy of lepromatous leprosy. ( , 1975) |
| "Acedapsone (DADDS), a repository sulfone given by injection five times a year, has been used since 1967 for the treatment of all leprosy patients in the Karimui, an area of diffic-lt access." | 9.04 | Acedapsone (DADDS) treatment of leprosy patients in the Karimui of Papua New Guinea: status at six years. ( McRae, DH; Russell, DA; Scott, GC; Shepard, CC; Vincin, DR, 1975) |
| "Dapsone-induced agranulocytosis is a rare adverse effect." | 8.79 | Dapsone agranulocytosis in a leprosy patient. ( Hiran, S; Pande, TK; Pani, S; Vishwanathan, KA, 1994) |
| "The occurrence of resistance to the current multidrug therapy regimen (specifically dapsone and rifampicin) and to ofloxacin, a secondary antileprosy medication in M." | 8.31 | High frequency of ofloxacin resistance patterns of Mycobacterium leprae from India: An indication to revisit second line anti-leprosy treatment regimen. ( Chhabra, S; Dogra, S; Jain, S; Kaur, M; Minz, RW; Nadeem, M; Narang, T; Pandey, P; Sahu, S; Sharma, A; Sharma, K; Sharma, R; Shilpa, S; Singh, I; Yadav, R, 2023) |
| "The mainstay of leprosy treatment is multidrug treatment (MDT), which contains rifampicin, dapsone and clofazimine." | 8.12 | Implementation of genetic screening test to reduce the incidence of dapsone hypersensitivity syndrome among patients with leprosy in Papua, Indonesia: a study protocol. ( Budiawan, T; Ferdiana, A; Imaniar, C; Irwanto, A; Krismawati, H; Mieras, L; Pongtiku, A; Singh, P; Wahyuni, T, 2022) |
| "Dapsone hypersensitivity syndrome (DHS) is the most serious adverse reaction associated with dapsone administration and one of the major causes of death in patients with leprosy, whose standard treatment includes multidrug therapy (MDT) with dapsone, rifampicin, and clofazimine." | 7.91 | Evaluation of Prospective HLA-B*13:01 Screening to Prevent Dapsone Hypersensitivity Syndrome in Patients With Leprosy. ( Bao, F; Cao, J; Cao, Q; Chai, Z; Chen, S; Cheng, X; Chu, T; Duan, Q; Fu, F; Fu, X; Irwanto, A; Ke, W; Krismawati, H; Kuang, Y; Lang, X; Li, J; Li, L; Li, M; Li, W; Lin, Z; Liu, D; Liu, H; Liu, J; Liu, Q; Mi, Z; Ning, Y; Pan, Q; Shang, X; Shen, J; Shen, Y; Sun, L; Sun, Y; Wang, C; Wang, H; Wang, L; Wang, X; Wang, Y; Wang, Z; Wu, W; Xiao, B; Xiao, P; Xiong, F; Xiong, J; Xiong, L; Xiong, M; Xu, Y; Yan, L; Yang, B; Yang, J; You, J; Yu, G; Yu, W; Yue, Z; Zhan, X; Zhang, F; Zhang, G; Zhang, H; Zhang, L; Zhang, Y; Zhao, Q; Zhao, W; Zheng, H, 2019) |
| "Six male patients of lepromatous leprosy with erythema nodosum leprosum reaction (ENL) reactions diagnosed clinically and by slit skin smear were treated with aspirin and clofazimine." | 7.83 | A Traditional NSAID Aspirin along with Clofazimine in Erythema Nodosum Leprosum Reaction: Study of Six Cases. ( Sharma, PK; Singh, DK, 2016) |
| "In the Netherlands dapsone is used for the treatment of dermatitis herpetiformis, leprosy and Pneumocystis jiroveci pneumonia and prophylaxis in case of cotrimoxazole allergy." | 7.83 | A lethal case of the dapsone hypersensitivity syndrome involving the myocardium. ( Beuers, U; de Boer, HH; de Vries, HJ; Hoogeveen, RM; Nellen, FJ; Thurlings, RM; van der Bom, T; van der Wal, AC; van Lent, AU; Wind, BS, 2016) |
| "Dapsone resistance is a serious impediment to the implementation of the present leprosy control strategies." | 7.83 | Discovery of a potential lead compound for treating leprosy with dapsone resistance mutation in M. leprae folP1. ( Dhanasekaran, D; Nawaz Khan, F; Nisha, J; Ramanathan, K; Shanthi, V, 2016) |
| "This study aims to assess the oxidative stress in leprosy patients under multidrug therapy (MDT; dapsone, clofazimine and rifampicin), evaluating the nitric oxide (NO) concentration, catalase (CAT) and superoxide dismutase (SOD) activities, glutathione (GSH) levels, total antioxidant capacity, lipid peroxidation, and methemoglobin formation." | 7.80 | Clinical oxidative stress during leprosy multidrug therapy: impact of dapsone oxidation. ( Batista Júnior, J; Borges, RS; Coleman, MD; Monteiro, MC; Oliveira, FR; Romão, PR; Salgado, CG; Schalcher, TR; Vieira, JL, 2014) |
| "We synthesized a series of novel dapsone-thalidomide hybrids (3a-i) by molecular hybridization and evaluated their potential for the treatment of type 2 leprosy reactions." | 7.80 | Synthesis and evaluation of novel dapsone-thalidomide hybrids for the treatment of type 2 leprosy reactions. ( Barbieri, KP; Carlos, IZ; Chelucci, RC; Chung, MC; de Faria Fernandes Belone, A; de Melo, TR; Diório, SM; do Nascimento, DC; dos Santos, JL; Placeres, MC; Rosa, PS; Yamasaki, PR, 2014) |
| "To Study the incidence and clinical characteristics of dapsone hypersensitivity syndrome (DHS) among MDT-treated leprosy patients from 2006 to 2009 in China." | 7.78 | Dapsone hypersensitivity syndrome among leprosy patients in China. ( Shen, J; Tian, W; Yan, L; Zhang, G; Zhou, M, 2012) |
| "Multidrug therapy for leprosy is currently done with dapsone, clofazimine and rifampicin." | 7.78 | Hemolytic anemia in patients receiving daily dapsone for the treatment of leprosy. ( Deps, P; Guerra, P; Nasser, S; Simon, M, 2012) |
| "Drug resistance surveillance identified six untreated leprosy patients in the Philippines with Mycobacterium leprae folP1 mutations which confer dapsone resistance." | 7.77 | Transmission of dapsone-resistant leprosy detected by molecular epidemiological approaches. ( Balagon, M; Brennan, PJ; Dela Pena, EL; Li, W; Lyons, DE; Maghanoy, AA; Mallari, IB; Nath, I; Orcullo, FM; Sakamuri, RM; Shinde, V; Tan, EV; Vissa, V, 2011) |
| "To evaluate the occurrence of relapse of multibacillary leprosy after multi-drug treatment including daily rifampin." | 7.77 | Evaluation of multi-drug therapy for leprosy in the United States using daily rifampin. ( Dacso, MM; Jacobson, RR; Prestigiacomo, JF; Scollard, DM; Stryjewska, BM, 2011) |
| "The study aimed to analyse the effect on the relapse rate of dapsone-cured multibacillary (MB) leprosy patients, of re-treatment, using a multidrug therapy (MDT) regimen which differed from the WHO recommended regimen." | 7.75 | Twenty five years follow up of MB leprosy patients retreated with a modified MDT regimen after a full course of dapsone mono-therapy. ( Chen, J; Jing, Z; Zhang, R; Zhou, D, 2009) |
| "Dapsone Hypersensitivity Syndrome (DHS) occurs in approximately 2% of leprosy patients in Nepal." | 7.74 | A retrospective study of the effect of modified multi-drug therapy in Nepali leprosy patients following the development of adverse effects due to dapsone. ( Pandey, B; Sapkota, BR; Shrestha, K; Walker, SL, 2008) |
| "Dapsone is a component of multi-drug therapy (MDT) for the treatment of all types of leprosy." | 7.74 | Mortality due to dapsone hypersensitivity syndrome complicating multi-drug therapy for leprosy in Nepal. ( Hawksworth, RA; Lewis, J; Pandey, B; Shrestha, K; Walker, SL, 2007) |
| "To detect the presence of rifampin- and dapsone-resistant strains of Mycobacterium leprae in three patients with recurring leprosy and clinically-suspected antimicrobial resistance through molecular techniques." | 7.74 | [Study of rifampin and dapsone resistance in three patients with recurring leprosy]. ( Beltrán, C; Cardona-Castro, N; Gómez, Y; Hernández, E; Kimura, M; Rodríguez, G; Villegas, S; Vissa, VD, 2008) |
| "Dapsone syndrome is a rare hypersensitivity reaction to dapsone and is characterized by high fever, papular or exfoliative dermatitis, progressing to liver toxicity and generalized lymphadenopathy, resembling a mononucleosis infection." | 7.73 | Dapsone syndrome with acute renal failure during leprosy treatment: case report. ( Alves-Rodrigues, EN; Fontes, CJ; Ribeiro, LC; Silva, MD; Takiuchi, A, 2005) |
| "To evaluate the haemoglobin concentration (Hb); total white blood cell count (WBC), differential WBC count; platelet count and reticulocyte count in leprosy patients already treated with dapsone." | 7.71 | Haematological alterations in leprosy patients treated with dapsone. ( Halim, NK; Ogbeide, E, 2002) |
| "There has been an increase in the reports of dapsone hypersensitivity syndrome (DHS) in the past few years, coinciding with the introduction of multidrug therapy (MDT) for leprosy world-wide." | 7.71 | Increase in the incidence of dapsone hypersensitivity syndrome--an appraisal. ( Lakshmi, TS; Rao, PN, 2001) |
| "Based upon the data from the Chinese National System for Leprosy Surveillance, this paper reports on the relapses in 297,343 leprosy patients [multibacillary (MB) 106,518, paucibacillary (PB) 190,825] cured by dapsone monotherapy." | 7.70 | Studies on risk of leprosy relapses in China: relapses after treatment with dapsone monotherapy. ( Chen, XS; Jiang, C; Li, WZ; Ye, GY, 1999) |
| "Dapsone (4,4'diaminodiphenyl-sulphone) commonly used in the treatment of patients who suffer from leprosy, is a strongly oxidative drug, producing damage to the red cell membrane." | 7.69 | [Vitamin E as protective agent against hemolysis in leprosy patients under dapsone treatment]. ( Artaza, JR; Carbia, CD; Díaz, NB; Lardo, MM; Nazer, R; Valdez, R, 1997) |
| "Long-term effectiveness of a dapsone compliance program was assessed in patients with leprosy." | 7.68 | Effectiveness of a dapsone compliance program in leprosy. ( Danziger, LH; Fischer, JH; Hill, C; Piscitelli, SC; Slajchert, AA; West, DP, 1993) |
| "Side-effects of leprosy treatment with dapsone are said to be uncommon, with drug allergy occurring in only one of every several hundred patients treated with dapsone." | 7.68 | Dapsone syndrome in Vanuatu: a high incidence during multidrug treatment (MDT) of leprosy. ( Ala, J; Hall, JJ; Reeve, PA, 1992) |
| "Before implementation of multidrug therapy (MDT), leprosy patients who were clinically inactive, skin-smear negative and had been treated with dapsone monotherapy for at least 5 years (paucibacillary patients) or for at least 10 years (multibacillary patients) were released from treatment." | 7.68 | Relapses in leprosy patients after release from dapsone monotherapy; experience in the leprosy control program of the all Africa Leprosy and Rehabilitation Training Center (ALERT) in Ethiopia. ( Becx-Bleumink, M, 1992) |
| "From 43 Nepalese leprosy patients skin smear negative, and treated with dapsone (diamino diphenyl sulphone), and without any sign of active leprosy or iritis, specimens from iridectomy during cataract surgery were studied histopathologically." | 7.68 | Histopathological findings in the iris of dapsone treated leprosy patients. ( Brandt, F; Pradhan, H; Rai, N; Shi, ZR; Thuladar, L; Zhou, HM, 1990) |
| "Haemolysis and frank anaemia from dapsone therapy of leprosy has been long recognized." | 7.68 | Effect of dapsone on haemoglobin concentration in patients with leprosy. ( Byrd, SR; Gelber, RH, 1991) |
| "The dapsone sensitivity of strains of Mycobacterium leprae from 54 multibacilliferous untreated leprosy patients presenting to the United States Public Health Service Hospital in San Francisco, California, U." | 7.67 | Primary dapsone-resistant leprosy in San Francisco. ( Gelber, RH, 1984) |
| "Sixteen patients, each receiving 100 mg of dapsone per day, were studied for evidence of hemolysis." | 7.67 | Vitamin E and dapsone-induced hemolysis. ( Kelly, JW; Marks, R; Sandland, M; Scott, J; Van der Weyden, MB, 1984) |
| "The basal level of blood ascorbic acid was studied in 70 cases of polar leprosy." | 7.67 | A study of blood ascorbic acid in leprosy. ( Bajaj, AK; Gupta, SC; Kumar, P; Singh, PA; Sinha, SN, 1984) |
| "In order to address the question whether hypersensitivity reactions to dapsone are becoming more frequent, the clinical data of 7300 leprosy patients treated between 1949 and September 1988 at the McKean Rehabilitation Centre in Thailand were reviewed." | 7.67 | Increased incidence in leprosy of hypersensitivity reactions to dapsone after introduction of multidrug therapy. ( Richardus, JH; Smith, TC, 1989) |
| "In Paraguay, the National Leprosy/Tuberculosis Program is based on a combined chemotherapy with isoprodian and rifampicin." | 7.67 | Isoprodian and rifampicin in the treatment of leprosy: a descriptive evaluation of therapy durations in 475 Paraguayan leprosy patients. ( Alvarenga, AE; Haubitz, I; Leguizamon, O; Pritze, S, 1989) |
| "The half time of disappearance of dapsone and monoacetyl dapsone and the acetylator phenotype of the leprosy patients who harboured dapsone sensitive and dapsone resistant M." | 7.67 | Influence of acetylator phenotype of the leprosy patient on the emergence of dapsone resistant leprosy. ( Aschhoff, M; Balakrishnan, S; Lilly, L; Raj, PP, 1988) |
| "Dapsone (DDS) in urine of 250 leprosy patients collected on surprise visits were screened by simple paper spot, tile tests and sensitive Enzyme linked immunosorbent assay (ELISA) and Haemagglutination inhibition (HI) tests." | 7.67 | Certain aspects of dapsone metabolism in leprosy patients as studied by high performance liquid chromatography (HPLC) and qualitative screening tests. ( Aschhoff, M; Balakrishnan, S; De Wit, M; Lilly, L; Raj, PP, 1988) |
| "In leprosy patients in Nigeria the influence of daily clofazimine and of once-monthly rifampicin on the pharmacokinetics of dapsone has been investigated." | 7.67 | Influence of once-monthly rifampicin and daily clofazimine on the pharmacokinetics of dapsone in leprosy patients in Nigeria. ( Pieters, FA; Woonink, F; Zuidema, J, 1988) |
| "In two field trials in Nigeria, 74 male and female leprosy outpatients received intra-adipose depot injections of either dapsone (DDS) or monoacetyldapsone (MADDS) at 4-week intervals." | 7.67 | A field trial among leprosy patients in Nigeria with depot injections of dapsone and monoacetyldapsone. ( Pieters, FA; Woonink, F; Zuidema, J, 1988) |
| "A simple urine spot test for monitoring patient compliance to dapsone self-administration in leprosy therapy was recommended by WHO but later abandoned." | 7.67 | A simple urine spot test for monitoring dapsone self-administration in leprosy treatment. ( Huikeshoven, H, 1986) |
| "A preliminary report is presented on the finding in a patient with lepromatous leprosy relapsing after maintaining clinical inactivity and bacterial negativity with dapsone monotherapy for a period of 23 years." | 7.67 | Combined clofazimine- and dapsone-resistant leprosy. A case report. ( Bhatia, VN; Harikrishnan, S; Kar, HK, 1986) |
| "Three regimens containing rifampin have been tried in paucibacillary leprosy patients." | 7.67 | Comparison of three regimens containing rifampin for treatment of paucibacillary leprosy patients. ( Desikan, KV; Katoch, K; Ramanathan, U; Ramu, G, 1987) |
| "Fifteen untreated leprosy patients were given rifampicin and dapsone for seven days, and then rifampicin, dapsone and clofazimine for seven days." | 7.67 | The effect of clofazimine on the pharmacokinetics of rifampicin and dapsone in leprosy. ( Bharadwaj, VP; Girdhar, BK; Mathur, A; Venkatesan, K, 1986) |
| "A 150 mg levamisole tablet once in every fortnight along with specific antileprosy drugs were administered to ten patients each in BL and LL groups of leprosy." | 7.67 | Effect of levamisole on bacterial index in BL and LL leprosy. ( Bera, DK; Sen, PC, 1985) |
| "Using the immunoperoxidase staining method, tissue muramidase (lysozyme) activity was studied in 34 nerve biopsies from leprosy patients and compared to findings in the skin." | 7.67 | Muramidase (lysozyme) findings in sural and radial nerve biopsies in leprosy patients after varying periods of treatment. ( Andersen, JG; Belehu, A; Haimanot, RT; McDougall, AC; Mshana, RN, 1985) |
| "The effects of dapsone on polymorphonuclear leukocyte functions and lymphocyte mitogen-induced transformation were assessed in vitro and in vivo in normal individuals and in newly diagnosed untreated patients with lepromatous leprosy." | 7.66 | In vitro and in vivo effects of dapsone on neutrophil and lymphocyte functions in normal individuals and patients with lepromatous leprosy. ( Anderson, R; Gatner, EM; Grabow, G; Imkamp, FM; Kok, SK; van Rensburg, AJ; van Rensburg, CE, 1981) |
| "A field survey was designed and carried out in parts of Kancheepuram and Tiruvannamalai Leprosy Control Units in Tamilnadu (population 418,000) with the objective of finding out the prevalence of secondary dapsone resistance among 790 lepromatous (LL and BL) cases, who formed the patient population at risk based on certain treatment criteria." | 7.66 | Prevalence survey of secondary dapsone resistance in leprosy in Kancheepuram and Tiruvannamalai control units of Tamil Nadu. ( Balakrishnan, S; Neelan, PN; Noordeen, SK; Pandian, PR, 1983) |
| "319 leprosy patients, attending our Mobile Treatment Unit, were monitored for their regularity of dapsone intake by (1) Physical verification of DDS tablets; and (2) Spot test, in the field." | 7.66 | Operational study to monitor the regularity of dapsone intake by leprosy out-patients. ( Balakrishnan, S; Kumar, A, 1983) |
| "At the Schieffelin Leprosy Research and Training Centre, Karagiri, India, 148 lepromatous (LL) and borderline lepromatous (BL) leprosy patients registered for treatment in the years 1971 to 1973 were found to respond as well to dapsone (DDS) monotherapy as 391 LL and BL patients registered in 1964 to 1966, as indicated by clearance of Mycobacterium leprae from skin smears during the initial seven years of therapy in each patient." | 7.66 | Response to dapsone (DDS) monotherapy in leprosy patients of Gudiyatham Taluk, South India: comparison between the 1960s and the 1970s. ( Almeida, JG; Chacko, CJ; Christian, M, 1983) |
| "A 13% incidence of hepatitis was observed among 54 cases of multibacillary leprosy treated daily with the three-drug combination of dapsone, rifampin, and a thioamide (ethionamide or prothionamide)." | 7.66 | Hepatitis in leprosy patients treated by a daily combination of dapsone, rifampin, and a thioamide. ( Cartel, JL; Grosset, JH; Guelpa-Lauras, CC; Millan, J, 1983) |
| "The effect of leprosy and dapsone (DDS) on the basal levels of blood lactic and pyruvic acids has been studied." | 7.66 | Effect of dapsone on blood lactic and pyruvic acids in leprosy. ( Bajaj, AK; Gupta, SC; Mehrotra, TN; Sinha, SN; Srivastava, NP, 1982) |
| "A survey of the prevalence of primary dapsone-resistant leprosy in Cebu, Philippines, has yielded an estimate of 3." | 7.66 | Primary dapsone-resistant leprosy in Cebu, Philippines. ( Cellona, RV; de la Cruz, EC; Fajardo, TT; Guinto, RS, 1981) |
| "Dapsone is the drug of first choice in the treatment of leprosy." | 7.66 | Intramuscular injection of dapsone in therapy for leprosy: a new approach. ( Huikeshoven, H; Leiker, DL; Merkus, FW; Modderman, ES; Zuidema, J, 1982) |
| "An operational study was undertaken (1) to monitor and assess the regularity of DDS intake by leprosy patients, (2) to find out the operational feasibility of methods used for monitoring dapsone intake, and (3) to study the factors influencing the regularity of drug intake." | 7.66 | Monitoring the regularity of self administration of dapsone by leprosy patients. ( Balakrishnan, S; Kumar, A, 1982) |
| "A preliminary study of the prevalence rate of secondary dapsone resistance among leprosy patients in Gudiyattam Taluk, Tamil Nadu, was undertaken." | 7.66 | Prevalence of secondary dapsone resistance in Gudiyattam Taluk, the leprosy control area of the Schieffelin Leprosy Research and Training Centre, Karigiri. 1. Preliminary report. ( Balraj, V; Chacko, CJ; Christian, M; Fritschi, EP; Jesudasan, K; Job, CK; Taylor, PM, 1980) |
| "Dapsone has been used in various dermatological disorders and in leprosy." | 7.66 | Dapsone induced hypohaptoglobinemia in lepromatous leprosy patients. ( Bharadwaj, VP; Girdhar, BK; Sritharan, V; Venkatesan, K, 1981) |
| "Fifty one patients with leprosy from the Urban Leprosy Centre, attached to the Department of Dermatology and Venereology, Goa Medical College on treatment with Dapsone were studied from the point of view of development of haemolysis related to the drug." | 7.66 | Dapsone haemolysis in leprosy. A preliminary report. ( Menezes, S; Rege, VL; Sehgal, VN, 1981) |
| "A Burmese boy being treated with dapsone (diaminodiphenylsulfone [DDS]), 100 mg daily, for lepromatous leprosy had a fatal reaction to the drug 3 weeks after therapy was started." | 7.66 | Fatal reaction to dapsone during treatment of leprosy. ( Borkowsky, W; Bullock, WE; Frey, HM; Gershon, AA, 1981) |
| "Two cases of tuberculoid leprosy who developed erythema multiforme bullosum (EMB) due to Dapsone (DDS) is reported." | 7.66 | Erythema multiforme bullosum due to dapsone. ( Dutta, RK, 1980) |
| "The 1,659 non-leprous people in a Micronesian population experiencing an annual leprosy incidence rate of about 7/1,000 were offered 15 acedapsone (DADDS) injections during 1967--1970 for leprosy prevention purposes." | 7.66 | Acedapsone in the prevention of leprosy: field trial in three high prevalence villages in Micronesia. ( Fasal, P; Jano, B; Russell, DA; Shepard, CC; Worth, RM, 1979) |
| "The Dapsone/creatinine ratio in random samples of urine was determined in 910 infectious leprosy patients attending the outpatient department of the Acworth Leprosy Hospital, Bombay during the period 20-9-76 to 20-11-1976." | 7.66 | Irregularity of Dapsone intake in infectious leprosy patients attending an urban treatment centre--its magnitude and causes. ( Naik, SS, 1978) |
| "A therapeutic trial using two dosages of Dapsone with a schedule of administration of the drug once a week was undertaken at the Central Leprosy Teaching and Research Institute, Chingleput." | 7.65 | A comparison of low and conventional dosages of dapsone in the treatment of lepromatous leprosy. ( Balakrishnan, S; Iyer, CG; Ramu, G, 1977) |
| "Dapsone/Creatinine in urine ratios were determined in statistically randomised samples of 965 leprosy patients attending out-patient department of Acworth Leprosy Hospital and 44 inmates of the Hospital." | 7.65 | Regularity of dapsone intake by leprosy patients attending urban treatment centre. ( Ganapati, R; Naik, SS, 1977) |
| "Patients of lepromatous leprosy who have evolved from the borderline type of disease are known to revert to the borderline state through a reactionary phenomenon under anti-leprosy chemotherapy with Dapsone." | 7.65 | Transformation from lepromatous to borderline leprosy under clofazimine therapy. ( Mahapatra, SB; Ramu, G, 1976) |
| "This paper summarises our clinical experience with clofazimine in the treatment of 25 cases of reactive states of lepromatous and borderline leprosy and 7 lepromatous patients not responding to dapsone." | 7.65 | Clinical trial with clofazimine in leprosy. ( Dongre, VV; Ganapati, R, 1976) |
| " The statistically significant difference between the two treatment groups indicates that, contrary to previous teaching, dapsone given in higher dosage does not predispose patients to reversal reactions and indeed may prevent them." | 6.64 | Evidence for prevention of borderline leprosy reactions by dapsone. ( Barnetson, RS; Pearson, JM; Rees, RJ, 1976) |
| "Leprosy is a stigmatizing, chronic infection which degenerates the nervous system and often leads to incapacitation." | 5.56 | Validation study of HLA-B*13:01 as a biomarker of dapsone hypersensitivity syndrome in leprosy patients in Indonesia. ( Irwan, ID; Irwanto, A; Krismawati, H; Liu, H; Liu, J; Maladan, Y; Oktavian, A; Pongtiku, A; Sitanggang, YA; Sun, Y; Tanjung, R; Wahyuni, T; Zhang, F, 2020) |
| "Dapsone resistance was found in 4 of 6 biopsies from American Samoa patients." | 5.48 | Dapsone Resistance in Leprosy Patients Originally from American Samoa, United States, 2010-2012. ( Araujo, S; Scollard, D; Stryjewska, BM; Williams, DL, 2018) |
| "The World Health Organization (WHO) recommends multidrug therapy (MDT) with rifampicin, dapsone, and clofazimine for treating leprosy, which is based on very low-quality evidence." | 5.41 | Seventy years of evidence on the efficacy and safety of drugs for treating leprosy: a network meta-analysis. ( Bao, F; Chen, J; Dong, Y; Fan, Y; Gao, L; Ji, Z; Kong, J; Li, B; Liu, A; Liu, M; Luo, S; Ma, W; Peng, L; Song, J; Wu, X; Yang, J, 2023) |
| "falciparum malaria was known for many years, there was no report about the incidence of P." | 5.32 | Malaria, leprosy and dapsone. ( Arora, VM; Chattopadhya, D; Kapoor, L; Saha, K, 2003) |
| "It is the drug of choice for the treatment of leprosy and prophylaxis of malaria." | 5.30 | Haematological and biochemical alterations in leprosy patients already treated with dapsone and MDT. ( Barbosa, JC; de Carvalho, D; de Souza, AM; Gouveia, E; Melchior Júnior, E; Queiroz, RH, 1997) |
| "Lymphocytes from patients with untreated lepromatous leprosy failed to respond to the M." | 5.26 | In vitro lymphocyte stimulation in patients with lepromatous and borderline tuberculoid leprosy. The effect of dapsone treatment on the response to Mycobacterium leprae antigens, tuberculin purified protein derivative and non-mycobacterial stimulants. ( Belehu, A; Closs, O; Reitan, LJ, 1982) |
| "Dapsone is one of the important drugs in the treatment of leprosy." | 5.22 | Risk factors for dapsone resistance in leprosy patients: a systematic meta-analysis. ( Jiang, H; Shi, Y; Wang, C; Wang, H; Wang, Z; Wu, Z, 2022) |
| "The 4,4'-diaminodiphenyl sulfone (DDS), also known as dapsone, is traditionally used as a potent anti-bacterial agent in clinical management of leprosy." | 5.22 | A comprehensive insight into the anti-inflammatory properties of dapsone. ( Dehpour, AR; Jourian, S; Khalilzadeh, M; Rahimi, M; Shayan, M; Sheibani, M, 2022) |
| "Dapsone (DDS), Rifampicin (RIF) and Ofloxacin (OFL) are drugs recommended by the World Health Organization (WHO) for the treatment of leprosy." | 5.22 | Drug Resistance (Dapsone, Rifampicin, Ofloxacin) and Resistance-Related Gene Mutation Features in Leprosy Patients: A Systematic Review and Meta-Analysis. ( Jin, G; Li, G; Li, X; Li, Y; Shao, Y; Wei, P; Yang, J; Zhang, L, 2022) |
| "Monthly doses of rifampin, ofloxacin, and minocycline (ROM) are expected to be effective treatment for multi-bacillary leprosy." | 5.11 | Parallel assessment of 24 monthly doses of rifampin, ofloxacin, and minocycline versus two years of World Health Organization multi-drug therapy for multi-bacillary leprosy. ( Abalos, RM; Balagon, MV; Cellona, RV; Dela Cruz, EC; Fajardo, TT; Tan, EV; Villahermosa, LG; Walsh, DS; Walsh, GP, 2004) |
| "Gastrointestinal toxicity and red skin discoloration were the major side effects observed in leprosy patients undergoing long-term treatment with clofazimine (CFZ)." | 5.10 | Biochemical and hematological side effects of clofazimine in leprosy patients. ( Costa Queiroz, RH; de Souza, AM; Melchior, E; Sampaio, SV, 2002) |
| "Methaemoglobinaemia and haemolytic anaemia were the principal side-effects observed in 30 leprosy patients undergoing long-term treatment with dapsone as a single drug or as part of multidrug therapy." | 5.08 | Influence of acetylator phenotype on the haematological and biochemical effects associated with dapsone in leprosy patients. ( Carvalho, D; Gouveia, EG; Melchior, E; Queiroz, RH; Souza, AM, 1997) |
| "A total of 307 patients with lepromatous leprosy and borderline lepromatous leprosy were randomized to dapsone monotherapy or to one of two types of drug combinations." | 5.07 | An international randomized study with long-term follow-up of single versus combination chemotherapy of multibacillary leprosy. ( Dietrich, M; Gaus, W; Kern, P; Meyers, WM, 1994) |
| "The cure rates of two treatment regimens in PB leprosy were compared in a prospective randomized trial: treatment U consisting of a single dose of rifampicin 40 mg/K bodyweight, and treatment A of rifampicin 1500 mg in a single dose, followed by one year of daily dapsone 100 mg." | 5.07 | A controlled therapeutic trial in paucibacillary leprosy comparing a single dose of rifampicin with a single dose of rifampicin followed by one year of daily dapsone. The Collaborative Study Group for the Treatment of Leprosy in Zaire. ( Groenen, G; Janssens, L; Kuykens, L; Mputu, LB; Pattyn, SR, 1991) |
| "The objective of the present study was to define short-course treatment regimens for PB leprosy and to compare them with the 'classical' dapsone treatment and the WHO-PB regimen." | 5.06 | Evaluation of five treatment regimens, using either dapsone monotherapy or several doses of rifampicin in the treatment of paucibacillary leprosy. ( Baquillon, G; Husser, JA; Jamet, P; Maiga, M; Pattyn, SR, 1990) |
| "Pyrazinamide in a dose of 1500 mg was given to 63 borderline lepromatous (BL) and lepromatous (LL) leprosy patients on different drug regimens for the initial 2 months of therapy." | 5.06 | Pyrazinamide as a part of combination therapy for BL and LL patients--a preliminary report. ( Katoch, K; Ramanathan, U; Ramu, G, 1988) |
| "In an international multicentre controlled single-blind trial of 93 previously untreated lepromatous leprosy patients the therapeutic effects of adding rifampicin, 450 mg/day orally or 1,200 mg once monthly in a single oral dose, to dapsone (50 mg/day orally) for the first 6 months of treatment were compared." | 5.05 | Once-monthly rifampicin plus daily dapsone in initial treatment of lepromatous leprosy. ( Ghosh, S; Hajra, SK; Languillon, J; McDougall, AC; Opromolla, DV; Tonello, CJ; Yawalkar, SJ, 1982) |
| "During treatment of multibacillary leprosy with the combination rifampin (RMP) 600 mg, ethionamide (ETH) 500 mg, and either dapsone (DDS) or clofazimine (CLO) 100 mg, hepatotoxicity was observed in 4." | 5.05 | Hepatotoxicity of the combination of rifampin-ethionamide in the treatment of multibacillary leprosy. ( Bourland, J; Davies, EM; Feracci, C; Grillone, S; Janssens, L; Pattyn, SR; Saylan, T, 1984) |
| "In this controlled trial in 35 patients with lepromatous leprosy the therapeutic effects of adding rifampin 450 mg daily (Regimen A) or 1200 mg once a month (Regimen B) to a standard dapsone regimen of 50 mg daily were practically identical." | 5.05 | A controlled trial to compare the therapeutic effects of dapsone in combination with daily or once-monthly rifampin in patients with lepromatous leprosy. ( McDougall, AC; Opromolla, DV; Tonello, CJ; Yawalkar, SJ, 1981) |
| "The effects of clofazimine on neutrophil activities such as random motility, migration to the leukoattractants endotoxin-activated serum and N-formyl-L-methionyl-L-leucyl-L-phenylalanine phagocytosis of Candida albicans, postphagocytic hexose-monophosphate shunt activity, and myeloperoxidase-mediated iodination and the effects of clofazimine on lymphocyte transformation to mitogens were assessed in vitro and after ingestion of the drug by normal individuals and patients with lepromatous leprosy." | 5.05 | Effects of clofazimine alone or combined with dapsone on neutrophil and lymphocyte functions in normal individuals and patients with lepromatous leprosy. ( Anderson, R; Gatner, EM; Imkamp, FM; van Rensburg, CE, 1982) |
| "A clinical trial was initiated at ALERT, Addis Ababa, Ethiopia, to study the effect of one-year supplementary treatment on the incidence of dapsone-resistant leprosy in lepromatous patients already on dapsone monotherapy." | 5.05 | Relapse rate and incidence of dapsone resistance in lepromatous leprosy patients in Addis Ababa: risk factors and effect of short-term supplementary treatment. ( Mengistu, G; Warndorff van Diepen, T, 1985) |
| "In the course of a clinical trial of acedapsone therapy in 17 patients with lepromatous leprosy, the rate of response to therapy was measured by inoculation of mice with Mycobacterium leprae recovered from biopsy specimens of skin lesions obtained before treatment and at intervals of 4, 12, and 24 weeks after institution of treatment." | 5.04 | Susceptibility of Mycobacterium leprae to dapsone as a determinant of patient response to acedapsone. ( Levy, L; Peters, JH, 1976) |
| "Patients with previously untreated borderline-lepromatous or fully lepromatous leprosy were treated with one of five clofazimine (B663) regimens: 1) 200 mg daily 6 days per week; 2) 100 mg three times weekly; 3) 300 mg weekly; 4) 600 mg every other week; and 5) 600 mg on 2 consecutive days every 4 weeks." | 5.04 | Spaced clofazimine therapy of lepromatous leprosy. ( , 1976) |
| "Patients with borderline-lepromatous (BL) or fully lepromatous (LL) leprosy were treated in the sanitarium for approximately 1 year with oral rifampin (600 mg daily) or with oral dapsone (100 mg daily)." | 5.04 | Rifampin therapy of lepromatous leprosy. ( , 1975) |
| "Acedapsone (DADDS), a repository sulfone given by injection five times a year, has been used since 1967 for the treatment of all leprosy patients in the Karimui, an area of diffic-lt access." | 5.04 | Acedapsone (DADDS) treatment of leprosy patients in the Karimui of Papua New Guinea: status at six years. ( McRae, DH; Russell, DA; Scott, GC; Shepard, CC; Vincin, DR, 1975) |
| "Rifampicin showed high activity against experimental leprosy, inhibiting the multiplication of dapsone-sensitive and dapsone-resistant strains of Mycobacterium leprae in mice fed 5 mg." | 5.03 | Experimental and clinical studies on rifampicin in treatment of leprosy. ( Pearson, JM; Rees, RJ; Waters, MF, 1970) |
| "A comparison of clofazimine and dapsone in the management of untreated lepromatous leprosy showed no significant differences between the two drugs in terms of morphological and bacterial indices." | 5.03 | Controlled clinical trial of clofazimine in untreated lepromatous leprosy. ( Jeevaratnam, A; Karat, AB; Karat, S; Rao, PS, 1971) |
| "From 1936 until 1996, the drug dapsone treated a diverse array of diseases, including tuberculosis, leprosy, malaria, and AIDS-related pneumonia." | 4.87 | A short history of dapsone, or an alternative model of drug development. ( Barr, J, 2011) |
| "Dapsone-induced agranulocytosis is a rare adverse effect." | 4.79 | Dapsone agranulocytosis in a leprosy patient. ( Hiran, S; Pande, TK; Pani, S; Vishwanathan, KA, 1994) |
| " Finally the combination of brodimoprim (BDP) and dapsone (DDS) was developed for the treatment of leprosy." | 4.78 | In vitro and in vivo results of brodimoprim and analogues alone and in combination against E. coli and mycobacteria. ( Seydel, JK, 1993) |
| "The occurrence of resistance to the current multidrug therapy regimen (specifically dapsone and rifampicin) and to ofloxacin, a secondary antileprosy medication in M." | 4.31 | High frequency of ofloxacin resistance patterns of Mycobacterium leprae from India: An indication to revisit second line anti-leprosy treatment regimen. ( Chhabra, S; Dogra, S; Jain, S; Kaur, M; Minz, RW; Nadeem, M; Narang, T; Pandey, P; Sahu, S; Sharma, A; Sharma, K; Sharma, R; Shilpa, S; Singh, I; Yadav, R, 2023) |
| "The mainstay of leprosy treatment is multidrug treatment (MDT), which contains rifampicin, dapsone and clofazimine." | 4.12 | Implementation of genetic screening test to reduce the incidence of dapsone hypersensitivity syndrome among patients with leprosy in Papua, Indonesia: a study protocol. ( Budiawan, T; Ferdiana, A; Imaniar, C; Irwanto, A; Krismawati, H; Mieras, L; Pongtiku, A; Singh, P; Wahyuni, T, 2022) |
| "Dapsone hypersensitivity syndrome (DHS) is the most serious adverse reaction associated with dapsone administration and one of the major causes of death in patients with leprosy, whose standard treatment includes multidrug therapy (MDT) with dapsone, rifampicin, and clofazimine." | 3.91 | Evaluation of Prospective HLA-B*13:01 Screening to Prevent Dapsone Hypersensitivity Syndrome in Patients With Leprosy. ( Bao, F; Cao, J; Cao, Q; Chai, Z; Chen, S; Cheng, X; Chu, T; Duan, Q; Fu, F; Fu, X; Irwanto, A; Ke, W; Krismawati, H; Kuang, Y; Lang, X; Li, J; Li, L; Li, M; Li, W; Lin, Z; Liu, D; Liu, H; Liu, J; Liu, Q; Mi, Z; Ning, Y; Pan, Q; Shang, X; Shen, J; Shen, Y; Sun, L; Sun, Y; Wang, C; Wang, H; Wang, L; Wang, X; Wang, Y; Wang, Z; Wu, W; Xiao, B; Xiao, P; Xiong, F; Xiong, J; Xiong, L; Xiong, M; Xu, Y; Yan, L; Yang, B; Yang, J; You, J; Yu, G; Yu, W; Yue, Z; Zhan, X; Zhang, F; Zhang, G; Zhang, H; Zhang, L; Zhang, Y; Zhao, Q; Zhao, W; Zheng, H, 2019) |
| "Dapsone (DAP) is a bactericidal agent used in the treatment of leprosy, caused by Mycobacterium leprae." | 3.91 | pH-responsive chitosan based hydrogels affect the release of dapsone: Design, set-up, and physicochemical characterization. ( Celia, C; Chaves, LL; Cristiano, MC; Di Marzio, L; Ferreira, D; Lima, SC; Paolino, D; Reis, S; Sarmento, B; Silveri, A; Vieira, ACC, 2019) |
| "From 2009 to 2015, multi-bacillary leprosy cases at sentinel sites of 19 countries were studied for resistance to rifampicin, dapsone and ofloxacin by PCR sequencing of the drug-resistance-determining regions of the genes rpoB, folP1 and gyrA." | 3.88 | Antimicrobial resistance in leprosy: results of the first prospective open survey conducted by a WHO surveillance network for the period 2009-15. ( Cambau, E; Cardona-Castro, N; Cauchoix, B; Cole, ST; Cooreman, EAWD; Gillini, L; Gupta, UD; Hagge, D; Hongseng, W; Indropo, A; Johnson, RC; Kai, M; Lavania, M; Matsuoka, M; Miyamoto, Y; Pannikar, VK; Pemmaraju, VRR; Rosa, PS; Saunderson, P; Srikantam, A; Suffys, P; Vissa, V; Williams, D, 2018) |
| " leprae to dapsone based on the folP1 drug resistance determining region (DRDR), rifampin (rpoB DRDR) and ofloxacin (gyrA DRDR) was evaluated using 211 clinical specimens from leprosy patients, including 156 multibacillary (MB) and 55 paucibacillary (PB) cases." | 3.85 | qPCR-High resolution melt analysis for drug susceptibility testing of Mycobacterium leprae directly from clinical specimens of leprosy patients. ( Araujo, S; Fontes, AB; Goulart, IMB; Goulart, LR; Li, W; Matsuoka, M; Rosa, PS; Scollard, DM; Suffys, P; Truman, RW; Vissa, V; Williams, DL, 2017) |
| "Dapsone (4,4'-diaminodiphenylsulfone) has been widely used for the treatment of infections such as leprosy." | 3.85 | A docking model of dapsone bound to HLA-B*13:01 explains the risk of dapsone hypersensitivity syndrome. ( Gouda, H; Hashizume, H; Kusakabe, Y; Mushiroda, T; Ozeki, T; Sueki, H; Tashiro, Y; Utsunomiya-Tate, N; Watanabe, H; Watanabe, Y; Yamamoto, T, 2017) |
| "Dapsone is an extensively Used drug for the treatment of leprosy as well as'some other clinical problems worldwide: Its use has been predicted to increase further, especially in non leprosy conditions." | 3.83 | Dapsone: An Update. ( Aruna, B; Kallappa, H; Karjigi, S; Kusuma, MR; Murthy, SC; Reddy, YN, 2016) |
| "Six male patients of lepromatous leprosy with erythema nodosum leprosum reaction (ENL) reactions diagnosed clinically and by slit skin smear were treated with aspirin and clofazimine." | 3.83 | A Traditional NSAID Aspirin along with Clofazimine in Erythema Nodosum Leprosum Reaction: Study of Six Cases. ( Sharma, PK; Singh, DK, 2016) |
| "In the Netherlands dapsone is used for the treatment of dermatitis herpetiformis, leprosy and Pneumocystis jiroveci pneumonia and prophylaxis in case of cotrimoxazole allergy." | 3.83 | A lethal case of the dapsone hypersensitivity syndrome involving the myocardium. ( Beuers, U; de Boer, HH; de Vries, HJ; Hoogeveen, RM; Nellen, FJ; Thurlings, RM; van der Bom, T; van der Wal, AC; van Lent, AU; Wind, BS, 2016) |
| "Dapsone resistance is a serious impediment to the implementation of the present leprosy control strategies." | 3.83 | Discovery of a potential lead compound for treating leprosy with dapsone resistance mutation in M. leprae folP1. ( Dhanasekaran, D; Nawaz Khan, F; Nisha, J; Ramanathan, K; Shanthi, V, 2016) |
| "This study aims to assess the oxidative stress in leprosy patients under multidrug therapy (MDT; dapsone, clofazimine and rifampicin), evaluating the nitric oxide (NO) concentration, catalase (CAT) and superoxide dismutase (SOD) activities, glutathione (GSH) levels, total antioxidant capacity, lipid peroxidation, and methemoglobin formation." | 3.80 | Clinical oxidative stress during leprosy multidrug therapy: impact of dapsone oxidation. ( Batista Júnior, J; Borges, RS; Coleman, MD; Monteiro, MC; Oliveira, FR; Romão, PR; Salgado, CG; Schalcher, TR; Vieira, JL, 2014) |
| "We synthesized a series of novel dapsone-thalidomide hybrids (3a-i) by molecular hybridization and evaluated their potential for the treatment of type 2 leprosy reactions." | 3.80 | Synthesis and evaluation of novel dapsone-thalidomide hybrids for the treatment of type 2 leprosy reactions. ( Barbieri, KP; Carlos, IZ; Chelucci, RC; Chung, MC; de Faria Fernandes Belone, A; de Melo, TR; Diório, SM; do Nascimento, DC; dos Santos, JL; Placeres, MC; Rosa, PS; Yamasaki, PR, 2014) |
| "We performed a genomewide association study involving 872 participants who had received dapsone as part of multidrug therapy for leprosy (39 participants with the dapsone hypersensitivity syndrome and 833 controls), using log-additive tests of single-nucleotide polymorphisms (SNPs) and imputed HLA molecules." | 3.79 | HLA-B*13:01 and the dapsone hypersensitivity syndrome. ( Bao, FF; Bei, JX; Chen, MF; Chen, SL; Chen, SM; Chen, XC; Chu, TS; de Bakker, PI; Foo, JN; Fu, XA; Huang, JX; Huang, ZM; Irwanto, A; Jia, XM; Li, JH; Li, JL; Li, M; Li, Y; Li, Z; Liany, H; Liu, DC; Liu, H; Liu, HX; Liu, J; Liu, JJ; Liu, YX; Liu, ZS; Long, H; Low, HQ; Lu, XM; Ma, SS; Ning, Y; Niu, GY; Pulit, SL; Shen, JP; Shi, BQ; Sun, YH; Tian, HQ; Wang, C; Wang, H; Wang, JQ; Wang, LM; Wang, N; Wang, XD; Wang, ZZ; Wei, ZH; Wu, WB; Xiao, P; Xiong, L; Yan, LB; Yang, J; Yang, Q; Yang, RD; You, JB; Yu, DB; Yu, GQ; Yu, XL; Yu, YX; Zeng, YX; Zhang, FR; Zhang, GC; Zhang, LH; Zhang, ZX; Zheng, ZY; Zhou, GZ; Zhou, Y, 2013) |
| "To Study the incidence and clinical characteristics of dapsone hypersensitivity syndrome (DHS) among MDT-treated leprosy patients from 2006 to 2009 in China." | 3.78 | Dapsone hypersensitivity syndrome among leprosy patients in China. ( Shen, J; Tian, W; Yan, L; Zhang, G; Zhou, M, 2012) |
| "Multidrug therapy for leprosy is currently done with dapsone, clofazimine and rifampicin." | 3.78 | Hemolytic anemia in patients receiving daily dapsone for the treatment of leprosy. ( Deps, P; Guerra, P; Nasser, S; Simon, M, 2012) |
| "From 1936 until 1996, the drug dapsone treated a diverse array of diseases, including tuberculosis, leprosy, malaria, and AIDS-related pneumonia." | 3.77 | A short history of dapsone, or an alternative model of drug development. ( Barr, J, 2011) |
| "Diaminodiphenylsulfone (dapsone) has long been used as a first-line drug worldwide for the treatment of leprosy." | 3.77 | Mutation analysis of the Mycobacterium leprae folP1 gene and dapsone resistance. ( Kai, M; Makino, M; Nakata, N, 2011) |
| " The second month of MDT was the riskiest for newly treated patients; approximately 20% of patients succumbed to liver failure, 33% to dapsone (diaminodiphenylsulfone/DDS) allergy, and 27% to renal insufficiency during this period." | 3.77 | Causes of death among active leprosy patients in China. ( Li, W; Liu, M; Shen, J; Zhou, M, 2011) |
| "Drug resistance surveillance identified six untreated leprosy patients in the Philippines with Mycobacterium leprae folP1 mutations which confer dapsone resistance." | 3.77 | Transmission of dapsone-resistant leprosy detected by molecular epidemiological approaches. ( Balagon, M; Brennan, PJ; Dela Pena, EL; Li, W; Lyons, DE; Maghanoy, AA; Mallari, IB; Nath, I; Orcullo, FM; Sakamuri, RM; Shinde, V; Tan, EV; Vissa, V, 2011) |
| "To evaluate the occurrence of relapse of multibacillary leprosy after multi-drug treatment including daily rifampin." | 3.77 | Evaluation of multi-drug therapy for leprosy in the United States using daily rifampin. ( Dacso, MM; Jacobson, RR; Prestigiacomo, JF; Scollard, DM; Stryjewska, BM, 2011) |
| "The study aimed to analyse the effect on the relapse rate of dapsone-cured multibacillary (MB) leprosy patients, of re-treatment, using a multidrug therapy (MDT) regimen which differed from the WHO recommended regimen." | 3.75 | Twenty five years follow up of MB leprosy patients retreated with a modified MDT regimen after a full course of dapsone mono-therapy. ( Chen, J; Jing, Z; Zhang, R; Zhou, D, 2009) |
| "Multidrug therapy (WHO/MDT) in multibacillary leprosy consists of treatment with rifampicin, dapsone and clofazimine." | 3.75 | Agranulocytosis induced by multidrug therapy in leprosy treatment: a case report. ( Guedes Filho, G; Guedes, WR; Oliveira, BB; Oliveira, CA; Oliveira, DA; Silva, IM, 2009) |
| "Dapsone Hypersensitivity Syndrome (DHS) occurs in approximately 2% of leprosy patients in Nepal." | 3.74 | A retrospective study of the effect of modified multi-drug therapy in Nepali leprosy patients following the development of adverse effects due to dapsone. ( Pandey, B; Sapkota, BR; Shrestha, K; Walker, SL, 2008) |
| "Dapsone is a component of multi-drug therapy (MDT) for the treatment of all types of leprosy." | 3.74 | Mortality due to dapsone hypersensitivity syndrome complicating multi-drug therapy for leprosy in Nepal. ( Hawksworth, RA; Lewis, J; Pandey, B; Shrestha, K; Walker, SL, 2007) |
| "The WHO MDT for leprosy treatment was officially introduced in Brazil in 1991 and comprises three drugs: dapsone, rifampicin and clofazimine." | 3.74 | Adverse effects from multi-drug therapy in leprosy: a Brazilian study. ( Birshner, Rde C; Deps, PD; Guerra, P; Nasser, S; Rodrigues, LC; Simon, M, 2007) |
| " By antibacterial activity one of these compounds was superior to dapsone, the main antileprosy drug." | 3.74 | Study of antileprosy activities of some dialkyldithiocarbamate derivatives. ( Daudova, AD; Makarov, VA; Urlyapova, NG; Yushchenko, AA, 2007) |
| "To detect the presence of rifampin- and dapsone-resistant strains of Mycobacterium leprae in three patients with recurring leprosy and clinically-suspected antimicrobial resistance through molecular techniques." | 3.74 | [Study of rifampin and dapsone resistance in three patients with recurring leprosy]. ( Beltrán, C; Cardona-Castro, N; Gómez, Y; Hernández, E; Kimura, M; Rodríguez, G; Villegas, S; Vissa, VD, 2008) |
| "Dapsone syndrome is a rare hypersensitivity reaction to dapsone and is characterized by high fever, papular or exfoliative dermatitis, progressing to liver toxicity and generalized lymphadenopathy, resembling a mononucleosis infection." | 3.73 | Dapsone syndrome with acute renal failure during leprosy treatment: case report. ( Alves-Rodrigues, EN; Fontes, CJ; Ribeiro, LC; Silva, MD; Takiuchi, A, 2005) |
| " The patient began treatment with clofazimine, rifampicin, and dapsone, but 15 days afterwards he complained of acral edema with godet sign." | 3.73 | Remitting seronegative symmetrical synovitis with pitting edema in leprosy. ( Helling, CA; Locursio, A; Manzur, ME; Sormani de Fonseca, ML, 2006) |
| "National Leprosy Control Programme was established in 1955 based on dapsone domiciliary treatment." | 3.73 | NLEP--current situation and strategy during the 11th plan period (2007-2012). ( Dhillon, GP, 2006) |
| "To evaluate the haemoglobin concentration (Hb); total white blood cell count (WBC), differential WBC count; platelet count and reticulocyte count in leprosy patients already treated with dapsone." | 3.71 | Haematological alterations in leprosy patients treated with dapsone. ( Halim, NK; Ogbeide, E, 2002) |
| "There has been an increase in the reports of dapsone hypersensitivity syndrome (DHS) in the past few years, coinciding with the introduction of multidrug therapy (MDT) for leprosy world-wide." | 3.71 | Increase in the incidence of dapsone hypersensitivity syndrome--an appraisal. ( Lakshmi, TS; Rao, PN, 2001) |
| "Currently recommended control measures for treating leprosy with multidrug therapy should control the spread of drug-resistant strains; however, dapsone (DDS) resistance continues to be reported." | 3.71 | Simultaneous detection of Mycobacterium leprae and its susceptibility to dapsone using DNA heteroduplex analysis. ( Gillis, TP; Kashiwabara, Y; Matsuoka, M; Pittman, TL; Williams, DL, 2001) |
| "Based upon the data from the Chinese National System for Leprosy Surveillance, this paper reports on the relapses in 297,343 leprosy patients [multibacillary (MB) 106,518, paucibacillary (PB) 190,825] cured by dapsone monotherapy." | 3.70 | Studies on risk of leprosy relapses in China: relapses after treatment with dapsone monotherapy. ( Chen, XS; Jiang, C; Li, WZ; Ye, GY, 1999) |
| "Many leprosy patients treated with multidrug therapy (MDT) had previously received dapsone (DDS) monotherapy for many years." | 3.69 | Relapse with multibacillary leprosy caused by rifampicin sensitive organisms following paucibacillary multidrug therapy. ( Britton, WJ; Neupane, K; Soares, DJ, 1995) |
| "Between 1986 and 1989, in 5 departments of Senegal, 436 new cases of leprosy were detected, of whom 225 were put under dapsone monotherapy and 211 under multidrug therapy (MDT)." | 3.69 | [The frequency of the appearance of perforating foot ulcers in patients with Hansen's disease as a function of treatment with disulone alone or with polychemotherapy]. ( Cartel, JL; Grauwin, MY; Mane, I, 1995) |
| "In this study of leprosy patients apparently cured by dapsone monotherapy, the polymerase chain reaction (PCR), one of the most reliable and sensitive DNA-based assays, was used for the specific detection of Mycobacterium leprae DNA." | 3.69 | Application of polymerase chain reaction for the detection of Mycobacterium leprae DNA in specimens from treated leprosy patients. ( Donoghue, HD; Rafi, A; Stanford, JL, 1995) |
| "An elderly patient with borderline tuberculoid Hansen's disease (leprosy) developed the diaminodiphenylsulphone syndrome after approximately 8 weeks of multi-drug therapy comprising dapsone and rifampicin." | 3.69 | A fatal case of drug-induced multi-organ damage in a patient with Hansen's disease: dapsone syndrome or rifampicin toxicity? ( Lau, G, 1995) |
| "Histoid leprosy is a rare form of multibacillary leprosy as the result of secondary or even primary resistance to dapsone." | 3.69 | Immunohistochemistry in histoid leprosy. ( Aroni, K; Kontochristopoulos, GJ; Panteleos, DN; Tosca, AD, 1995) |
| "At a time when primary dapsone resistance was prevalent in many leprosy endemic areas, Cebu in The Philippines reported only 3." | 3.69 | Primary dapsone resistance in Cebu, The Philippines; cause for concern. ( Abalos, RM; Balagon, MV; Cellona, RV; dela Cruz, E; Fajardo, TT; Tan, EV; Villahermosa, LG; Walsh, GP, 1996) |
| "Dapsone (4,4'diaminodiphenyl-sulphone) commonly used in the treatment of patients who suffer from leprosy, is a strongly oxidative drug, producing damage to the red cell membrane." | 3.69 | [Vitamin E as protective agent against hemolysis in leprosy patients under dapsone treatment]. ( Artaza, JR; Carbia, CD; Díaz, NB; Lardo, MM; Nazer, R; Valdez, R, 1997) |
| " At the time of study, 29 of the Aborigines were receiving acedapsone intramuscularly for control of leprosy." | 3.68 | Acetylation phenotype and genotype in aboriginal leprosy patients from the north-west region of Western Australia. ( Chiswell, GM; Ilett, KF; Minchin, RF; Platt, E; Spargo, RM, 1993) |
| "To describe the role of the clinical pharmacist in a Hansen's disease (HD, leprosy) clinic and to describe the development, validation, and operation of a dapsone compliance monitoring program." | 3.68 | Therapeutic monitoring and pharmacist intervention in a Hansen's disease clinic. ( Danziger, LH; Fischer, JH; Hill, C; Occhipinti, DJ; Piscitelli, SC; West, DP, 1993) |
| "The proportion of relapses among all patients detected each year increased steadily since the initiation of the national leprosy control program in China with dapsone monotherapy in 1955, reaching 18%-24% in the more leprosy-endemic provinces along the coast." | 3.68 | Problems of leprosy relapse in China. ( Li, HY, 1993) |
| "We analyzed the records of 1022 patients of paucibacillary leprosy who had received either 6 doses of WHO-MDT alone (" classical" MDT, 668 patients) or had post-MDT dapsone for at least 6 months ("modified" MDT, 354 patients)." | 3.68 | Fixed duration MDT in paucibacillary leprosy (classical and modified). ( Grugni, A; Kini, MS; Nadkarni, NJ, 1993) |
| "Long-term effectiveness of a dapsone compliance program was assessed in patients with leprosy." | 3.68 | Effectiveness of a dapsone compliance program in leprosy. ( Danziger, LH; Fischer, JH; Hill, C; Piscitelli, SC; Slajchert, AA; West, DP, 1993) |
| "Side-effects of leprosy treatment with dapsone are said to be uncommon, with drug allergy occurring in only one of every several hundred patients treated with dapsone." | 3.68 | Dapsone syndrome in Vanuatu: a high incidence during multidrug treatment (MDT) of leprosy. ( Ala, J; Hall, JJ; Reeve, PA, 1992) |
| "In 1982, following the recommendations of a WHO study group, multidrug therapy (MDT) was introduced into French Polynesia to treat all patients suffering from active leprosy, and--only on request--those still on dapsone monotherapy." | 3.68 | Leprosy in French Polynesia. The possible impact of multidrug therapy on epidemiological trends. ( Cartel, JL; Grosset, JH; Martin, PM; Moulia-Pelat, JP; Nguyen Ngoc, L; Spiegel, A, 1992) |
| "Before implementation of multidrug therapy (MDT), leprosy patients who were clinically inactive, skin-smear negative and had been treated with dapsone monotherapy for at least 5 years (paucibacillary patients) or for at least 10 years (multibacillary patients) were released from treatment." | 3.68 | Relapses in leprosy patients after release from dapsone monotherapy; experience in the leprosy control program of the all Africa Leprosy and Rehabilitation Training Center (ALERT) in Ethiopia. ( Becx-Bleumink, M, 1992) |
| "An ambulatory treatment regimen for multibacillary leprosy, of 34 weeks duration composed of 8 weeks daily supervised rifampicin, ethionamide (ETH), dapsone (DDS) and clofazimine (CLO) followed by 26 weeks of unsupervised ETH, DDS and CLO, introduced in 1983 has been evaluated; 268 patients were followed for a mean of 4." | 3.68 | Ambulatory treatment of multibacillary leprosy with a regimen of 8 months duration. ( Bourland, J; Pattyn, SR, 1992) |
| "From 43 Nepalese leprosy patients skin smear negative, and treated with dapsone (diamino diphenyl sulphone), and without any sign of active leprosy or iritis, specimens from iridectomy during cataract surgery were studied histopathologically." | 3.68 | Histopathological findings in the iris of dapsone treated leprosy patients. ( Brandt, F; Pradhan, H; Rai, N; Shi, ZR; Thuladar, L; Zhou, HM, 1990) |
| "Haemolysis and frank anaemia from dapsone therapy of leprosy has been long recognized." | 3.68 | Effect of dapsone on haemoglobin concentration in patients with leprosy. ( Byrd, SR; Gelber, RH, 1991) |
| "The epidemiometric model of leprosy, built on Polambakkam, India, data, is used to compare the impact on incidence of dapsone and different multidrug therapy (MDT) strategies." | 3.68 | Selection of MDT strategies through epidemiometric modeling. ( Declercq, EE; Lechat, MF; Misson, CB; Vellut, CM, 1990) |
| "The feasibility and effects of a 3-year treatment using rifampicin (RFP), clofazimine (B663) and dapsone (DDS) in multibacillary leprosy patients in Yangzhou Prefecture and Dongtai County (1983-1986) are reported." | 3.68 | Effect of three-year multidrug therapy in multibacillary leprosy patients. ( Ji, F; Li, W; Luo, J; Tao, M; Wang, C; Yang, Z; Ye, G, 1990) |
| "The dapsone sensitivity of strains of Mycobacterium leprae from 54 multibacilliferous untreated leprosy patients presenting to the United States Public Health Service Hospital in San Francisco, California, U." | 3.67 | Primary dapsone-resistant leprosy in San Francisco. ( Gelber, RH, 1984) |
| "A 24 year old man admitted to hospital with borderline lepromatous leprosy was treated with rifampicin, dapsone, and clofazimine." | 3.67 | Successful plasma exchange in type 1 leprosy reversal reaction. ( Bonhomme, J; Chalopin, JM; Lucht, F; Portier, H; Rifle, G, 1984) |
| "Sixteen patients, each receiving 100 mg of dapsone per day, were studied for evidence of hemolysis." | 3.67 | Vitamin E and dapsone-induced hemolysis. ( Kelly, JW; Marks, R; Sandland, M; Scott, J; Van der Weyden, MB, 1984) |
| "The basal level of blood ascorbic acid was studied in 70 cases of polar leprosy." | 3.67 | A study of blood ascorbic acid in leprosy. ( Bajaj, AK; Gupta, SC; Kumar, P; Singh, PA; Sinha, SN, 1984) |
| "For the evaluation of cancer risks associated with immunodeficiencies experienced by patients with Hansen's disease (leprosy) and for the assessment of possible adverse effects of dapsone therapy, a follow-up study was conducted of 1,678 patients admitted to the National Hansen's Disease Center in Carville, La." | 3.67 | Cancer mortality among patients with Hansen's disease. ( Brinton, LA; Fraumeni, JF; Hoover, R; Jacobson, RR, 1984) |
| "Single dose kinetics of norethisterone (NET) and ethinyl estradiol (EE) were investigated in 10 female leprosy patients following the ingestion of a contraceptive pill (NET acetate 1 mg + 30 EE mcg)." | 3.67 | Norethisterone and ethinyl estradiol kinetics during dapsone therapy. ( Bhatki, S; Joshi, JV; Joshi, UM; Maitra, A; Sankolli, G, 1984) |
| "In order to address the question whether hypersensitivity reactions to dapsone are becoming more frequent, the clinical data of 7300 leprosy patients treated between 1949 and September 1988 at the McKean Rehabilitation Centre in Thailand were reviewed." | 3.67 | Increased incidence in leprosy of hypersensitivity reactions to dapsone after introduction of multidrug therapy. ( Richardus, JH; Smith, TC, 1989) |
| "In Paraguay, the National Leprosy/Tuberculosis Program is based on a combined chemotherapy with isoprodian and rifampicin." | 3.67 | Isoprodian and rifampicin in the treatment of leprosy: a descriptive evaluation of therapy durations in 475 Paraguayan leprosy patients. ( Alvarenga, AE; Haubitz, I; Leguizamon, O; Pritze, S, 1989) |
| "The self administration of dapsone by Nepali leprosy patients receiving multidrug therapy was assessed by a colorimetric and a filter paper spot test." | 3.67 | Self-administered drug compliance in Nepali leprosy patients. ( Britton, W; Failbus, S; Roche, PW, 1989) |
| "Fifty three multibacillary leprosy cases were treated with two regimens of MDT L1 consisting of Rifampicin, Dapsone and Ethionamide and L2 consisting of Rifampicin, Dapsone and clofazimine." | 3.67 | Evaluation of two multidrug regimen in hospitalised multibacillary cases. ( Bhate, RD; Bhate, RP; Chattopadhyay, SP; Gupta, CM, 1989) |
| "Three multidrug regimens all containing rifampin and dapsone have been tried for the treatment of 278 cases of paucibacillary leprosy." | 3.67 | Relapses in paucibacillary patients after treatment with three short-term regimens containing rifampin. ( Bagga, AK; Bhatia, AS; Katoch, K; Natrajan, M; Ramanathan, U; Ramu, G; Saxena, RK, 1989) |
| "The incidence rate of leprosy among 517 household contacts of 113 cases of secondary dapsone resistance with 5074 person years at risk were studied." | 3.67 | Infectivity of secondary dapsone-resistant cases. ( Christian, M; Jesudasan, K; Pannikar, V, 1988) |
| "The half time of disappearance of dapsone and monoacetyl dapsone and the acetylator phenotype of the leprosy patients who harboured dapsone sensitive and dapsone resistant M." | 3.67 | Influence of acetylator phenotype of the leprosy patient on the emergence of dapsone resistant leprosy. ( Aschhoff, M; Balakrishnan, S; Lilly, L; Raj, PP, 1988) |
| "Dapsone (DDS) in urine of 250 leprosy patients collected on surprise visits were screened by simple paper spot, tile tests and sensitive Enzyme linked immunosorbent assay (ELISA) and Haemagglutination inhibition (HI) tests." | 3.67 | Certain aspects of dapsone metabolism in leprosy patients as studied by high performance liquid chromatography (HPLC) and qualitative screening tests. ( Aschhoff, M; Balakrishnan, S; De Wit, M; Lilly, L; Raj, PP, 1988) |
| "In leprosy patients in Nigeria the influence of daily clofazimine and of once-monthly rifampicin on the pharmacokinetics of dapsone has been investigated." | 3.67 | Influence of once-monthly rifampicin and daily clofazimine on the pharmacokinetics of dapsone in leprosy patients in Nigeria. ( Pieters, FA; Woonink, F; Zuidema, J, 1988) |
| "In two field trials in Nigeria, 74 male and female leprosy outpatients received intra-adipose depot injections of either dapsone (DDS) or monoacetyldapsone (MADDS) at 4-week intervals." | 3.67 | A field trial among leprosy patients in Nigeria with depot injections of dapsone and monoacetyldapsone. ( Pieters, FA; Woonink, F; Zuidema, J, 1988) |
| "Pharmacokinetics of aspirin and chloramphenicol was studied in 16 normal and 16 patients suffering from leprosy." | 3.67 | Pharmacokinetics of aspirin and chloramphenicol in normal and leprotic patients before and after dapsone therapy. ( Bakaya, V; Garg, SK; Kaur, S; Kumar, B; Lal, R; Shukla, VK, 1988) |
| "A simple urine spot test for monitoring patient compliance to dapsone self-administration in leprosy therapy was recommended by WHO but later abandoned." | 3.67 | A simple urine spot test for monitoring dapsone self-administration in leprosy treatment. ( Huikeshoven, H, 1986) |
| "Because of the recent spate of reports of primary resistance to dapsone among patients with lepromatous leprosy, largely to small concentrations of the drug, a survey was made of the results of dapsone-susceptibility testing of strains of Mycobacterium leprae isolated before 1977 among six laboratories which employed the mouse foot pad technique for this work prior to that time." | 3.67 | Susceptibility of strains of Mycobacterium leprae isolated prior to 1977 from patients with previously untreated lepromatous leprosy. ( Baohong, J; Dela Cruz, EC; Levy, L; Pattyn, SR; Rees, RJ; Shepard, CC, 1986) |
| "A preliminary report is presented on the finding in a patient with lepromatous leprosy relapsing after maintaining clinical inactivity and bacterial negativity with dapsone monotherapy for a period of 23 years." | 3.67 | Combined clofazimine- and dapsone-resistant leprosy. A case report. ( Bhatia, VN; Harikrishnan, S; Kar, HK, 1986) |
| "The rise in the incidence of dapsone-resistant leprosy requires new therapeutic approaches." | 3.67 | [Therapy of leprosy today]. ( Bahmer, FA; Menzel, S, 1987) |
| "Three regimens containing rifampin have been tried in paucibacillary leprosy patients." | 3.67 | Comparison of three regimens containing rifampin for treatment of paucibacillary leprosy patients. ( Desikan, KV; Katoch, K; Ramanathan, U; Ramu, G, 1987) |
| "The existence of an association between regularity in dapsone intake and the development of deformity was investigated in 5746 leprosy patients under treatment in South India." | 3.67 | Association between regularity in dapsone (DDS) treatment and development of deformity. ( Nair, NG; Radhakrishna, S, 1987) |
| "Fifteen untreated leprosy patients were given rifampicin and dapsone for seven days, and then rifampicin, dapsone and clofazimine for seven days." | 3.67 | The effect of clofazimine on the pharmacokinetics of rifampicin and dapsone in leprosy. ( Bharadwaj, VP; Girdhar, BK; Mathur, A; Venkatesan, K, 1986) |
| "A 150 mg levamisole tablet once in every fortnight along with specific antileprosy drugs were administered to ten patients each in BL and LL groups of leprosy." | 3.67 | Effect of levamisole on bacterial index in BL and LL leprosy. ( Bera, DK; Sen, PC, 1985) |
| "Using the immunoperoxidase staining method, tissue muramidase (lysozyme) activity was studied in 34 nerve biopsies from leprosy patients and compared to findings in the skin." | 3.67 | Muramidase (lysozyme) findings in sural and radial nerve biopsies in leprosy patients after varying periods of treatment. ( Andersen, JG; Belehu, A; Haimanot, RT; McDougall, AC; Mshana, RN, 1985) |
| "A comparative study with 2 tier and 3 tier combination of Rifampicin, Clofazimine, DDS, INAH and Thiacetazone was conducted on fifty lepromatous leprosy cases for varying periods." | 3.66 | Multiple drug therapy--a comparative study with 2 tier and 3 tier combination of rifampicin, clofazimine, DDS, INAH and thiacetazone in lepromatous cases. ( Chaudhury, S; Ghosh, S; Hazra, S; Kundu, SK, 1981) |
| "The effects of dapsone on polymorphonuclear leukocyte functions and lymphocyte mitogen-induced transformation were assessed in vitro and in vivo in normal individuals and in newly diagnosed untreated patients with lepromatous leprosy." | 3.66 | In vitro and in vivo effects of dapsone on neutrophil and lymphocyte functions in normal individuals and patients with lepromatous leprosy. ( Anderson, R; Gatner, EM; Grabow, G; Imkamp, FM; Kok, SK; van Rensburg, AJ; van Rensburg, CE, 1981) |
| "A field survey was designed and carried out in parts of Kancheepuram and Tiruvannamalai Leprosy Control Units in Tamilnadu (population 418,000) with the objective of finding out the prevalence of secondary dapsone resistance among 790 lepromatous (LL and BL) cases, who formed the patient population at risk based on certain treatment criteria." | 3.66 | Prevalence survey of secondary dapsone resistance in leprosy in Kancheepuram and Tiruvannamalai control units of Tamil Nadu. ( Balakrishnan, S; Neelan, PN; Noordeen, SK; Pandian, PR, 1983) |
| "Anti-Mycobacterium leprae antigen 7 antibody activity was determined by radioimmunoassay during treatment in a longtime study of individual patients with newly diagnosed borderline tuberculoid (BT) leprosy and in BT leprosy patients who were suspected from their case histories to have dapsone (DDS) resistant leprosy." | 3.66 | Effect of treatment on antibody activity against Mycobacterium leprae antigen 7 in tuberculoid leprosy. ( Belehu, A; Dahle, JS; Harboe, M; Touw Langendijk, EJ; van Diepen, TW, 1983) |
| "Exfoliative dermatitis associated with hepatitis has been reported in leprosy patients taking dapsone in daily dosage of 200 mg daily or more previously." | 3.66 | Sulphone induced exfoliative dermatitis and hepatitis. ( Garg, BR; Lal, S, 1980) |
| "The practical problems related to dapsone monotherapy for a prolonged period to infectious leprosy patients are well known to the scientific community and combined treatment of dapsone with clofazimine, rifampicin or prothionamide has been successfully carried out by several workers in hospitalised leprosy patients." | 3.66 | Field application of combined therapy for infectious leprosy cases. A feasibility study in Bombay. ( Ganapati, R; Naik, SS; Revankar, CR, 1983) |
| "319 leprosy patients, attending our Mobile Treatment Unit, were monitored for their regularity of dapsone intake by (1) Physical verification of DDS tablets; and (2) Spot test, in the field." | 3.66 | Operational study to monitor the regularity of dapsone intake by leprosy out-patients. ( Balakrishnan, S; Kumar, A, 1983) |
| "Oral zinc sulfate was tried in Eight cases of recurrent Erythema Nodosum Leprosum." | 3.66 | Oral zinc in recurrent Erythema Nodosum Leprosum reaction. ( Bumb, RA; Mangal, HN; Mathur, NK, 1983) |
| "At the Schieffelin Leprosy Research and Training Centre, Karigiri, India, a study of the population of Gudiyatham Taluk revealed that the prevalence of dapsone (DDS)-resistant infection among lepromatous (LL) and borderline lepromatous (BL) leprosy patients treated for a minimum of three years was 3." | 3.66 | DDS-resistant infection among leprosy patients in the population of Gudiyatham Taluk, South India. Part 3. Prevalence, incidence, risk factors, and interpretation of mouse foot pad test results. ( Almeida, JG; Chacko, CJ; Christian, M; Fritschi, EP; Taylor, PM, 1983) |
| "In a stable rural population of South India, 18 consecutive untreated persons newly discovered to have leprosy with a Bacterial Index (BI) greater than or equal to 2+ were tested for Mycobacterium leprae resistant to dapsone (DDS) by the mouse foot pad test." | 3.66 | The significance of dapsone (DDS)-resistant Mycobacterium leprae in untreated patients. ( Almeida, JG; Chacko, CJ; Christian, M, 1983) |
| "At the Schieffelin Leprosy Research and Training Centre, Karagiri, India, 148 lepromatous (LL) and borderline lepromatous (BL) leprosy patients registered for treatment in the years 1971 to 1973 were found to respond as well to dapsone (DDS) monotherapy as 391 LL and BL patients registered in 1964 to 1966, as indicated by clearance of Mycobacterium leprae from skin smears during the initial seven years of therapy in each patient." | 3.66 | Response to dapsone (DDS) monotherapy in leprosy patients of Gudiyatham Taluk, South India: comparison between the 1960s and the 1970s. ( Almeida, JG; Chacko, CJ; Christian, M, 1983) |
| "A 13% incidence of hepatitis was observed among 54 cases of multibacillary leprosy treated daily with the three-drug combination of dapsone, rifampin, and a thioamide (ethionamide or prothionamide)." | 3.66 | Hepatitis in leprosy patients treated by a daily combination of dapsone, rifampin, and a thioamide. ( Cartel, JL; Grosset, JH; Guelpa-Lauras, CC; Millan, J, 1983) |
| " leprae antigen 7 was demonstrated after one year of dapsone (DDS) treatment in 14 of 15 patients with lepromatous (BL-LL) leprosy." | 3.66 | Class specific anti-Mycobacterium leprae antibody assay in lepromatous leprosy (BL-LL) patients during the first two to four years of DDS treatment. ( Harboe, M; Melsom, R; Naafs, B, 1982) |
| "Available reports both from rural and urban leprosy centres prove beyond any doubt that dapsone is not being consumed regularly by all those who show regular clinic attendance." | 3.66 | Dapsone compliance in an urban field project. ( Ganapati, R; Naik, SS; Revankar, CR, 1983) |
| "The effect of leprosy and dapsone (DDS) on the basal levels of blood lactic and pyruvic acids has been studied." | 3.66 | Effect of dapsone on blood lactic and pyruvic acids in leprosy. ( Bajaj, AK; Gupta, SC; Mehrotra, TN; Sinha, SN; Srivastava, NP, 1982) |
| "A survey of the prevalence of primary dapsone-resistant leprosy in Cebu, Philippines, has yielded an estimate of 3." | 3.66 | Primary dapsone-resistant leprosy in Cebu, Philippines. ( Cellona, RV; de la Cruz, EC; Fajardo, TT; Guinto, RS, 1981) |
| "A patient with tuberculoid leprosy and chronic renal failure was given a renal allograft after 5 months of dapsone (DDS) treatment." | 3.66 | Renal transplantation in leprosy. ( Date, A; Mathai, R; Pandey, AP; Shastry, JC, 1982) |
| "Dapsone is the drug of first choice in the treatment of leprosy." | 3.66 | Intramuscular injection of dapsone in therapy for leprosy: a new approach. ( Huikeshoven, H; Leiker, DL; Merkus, FW; Modderman, ES; Zuidema, J, 1982) |
| "An operational study was undertaken (1) to monitor and assess the regularity of DDS intake by leprosy patients, (2) to find out the operational feasibility of methods used for monitoring dapsone intake, and (3) to study the factors influencing the regularity of drug intake." | 3.66 | Monitoring the regularity of self administration of dapsone by leprosy patients. ( Balakrishnan, S; Kumar, A, 1982) |
| "A preliminary study of the prevalence rate of secondary dapsone resistance among leprosy patients in Gudiyattam Taluk, Tamil Nadu, was undertaken." | 3.66 | Prevalence of secondary dapsone resistance in Gudiyattam Taluk, the leprosy control area of the Schieffelin Leprosy Research and Training Centre, Karigiri. 1. Preliminary report. ( Balraj, V; Chacko, CJ; Christian, M; Fritschi, EP; Jesudasan, K; Job, CK; Taylor, PM, 1980) |
| "Dapsone has been used in various dermatological disorders and in leprosy." | 3.66 | Dapsone induced hypohaptoglobinemia in lepromatous leprosy patients. ( Bharadwaj, VP; Girdhar, BK; Sritharan, V; Venkatesan, K, 1981) |
| "Quantitative estimations of porphyrin in the blood, urine, and feces of 30 leprosy patients under treatment with dapsone, ten untreated cases, and 100 normal subjects were done by Rimington's method." | 3.66 | A quantitative assay of porphyrins in leprosy patients. A spectrophotometric study. ( Handa, F; Pavithran, P; Sidhu, KS, 1981) |
| "Fifty one patients with leprosy from the Urban Leprosy Centre, attached to the Department of Dermatology and Venereology, Goa Medical College on treatment with Dapsone were studied from the point of view of development of haemolysis related to the drug." | 3.66 | Dapsone haemolysis in leprosy. A preliminary report. ( Menezes, S; Rege, VL; Sehgal, VN, 1981) |
| "A Burmese boy being treated with dapsone (diaminodiphenylsulfone [DDS]), 100 mg daily, for lepromatous leprosy had a fatal reaction to the drug 3 weeks after therapy was started." | 3.66 | Fatal reaction to dapsone during treatment of leprosy. ( Borkowsky, W; Bullock, WE; Frey, HM; Gershon, AA, 1981) |
| "Two cases of tuberculoid leprosy who developed erythema multiforme bullosum (EMB) due to Dapsone (DDS) is reported." | 3.66 | Erythema multiforme bullosum due to dapsone. ( Dutta, RK, 1980) |
| "The 1,659 non-leprous people in a Micronesian population experiencing an annual leprosy incidence rate of about 7/1,000 were offered 15 acedapsone (DADDS) injections during 1967--1970 for leprosy prevention purposes." | 3.66 | Acedapsone in the prevention of leprosy: field trial in three high prevalence villages in Micronesia. ( Fasal, P; Jano, B; Russell, DA; Shepard, CC; Worth, RM, 1979) |
| "35 cases of lepromatous leprosy were studied to evaluate the effective blood level and long depot action of acedapsone (DADDS)." | 3.66 | Activity and effective serum level of repository sulphones (DADDS) in lepromatous leprosy. ( Anand, LC; Rathore, BS, 1979) |
| "A study was undertaken to probe into the influence of ascorbic acid on the absorption and metabolism of administered DDS in leprosy patients." | 3.66 | Effect of ascorbic acid on blood levels of DDS. ( Bharadwaj, VP; Girdhar, BK; Venkatesan, K, 1979) |
| "The Dapsone/creatinine ratio in random samples of urine was determined in 910 infectious leprosy patients attending the outpatient department of the Acworth Leprosy Hospital, Bombay during the period 20-9-76 to 20-11-1976." | 3.66 | Irregularity of Dapsone intake in infectious leprosy patients attending an urban treatment centre--its magnitude and causes. ( Naik, SS, 1978) |
| " Lucio's phenomenon is a syndrome distinct from erythema nodosum leprosum as indicated by an absence of fever, leukocytosis and tenderness, a failure to respond to thalidomide, and a restriction to patients with diffuse nonnodular lepromatous leprosy." | 3.66 | Lucio's phenomenon and diffuse nonnodular lepromatous leprosy. ( Levan, NE; Rea, TH, 1978) |
| "A therapeutic trial using two dosages of Dapsone with a schedule of administration of the drug once a week was undertaken at the Central Leprosy Teaching and Research Institute, Chingleput." | 3.65 | A comparison of low and conventional dosages of dapsone in the treatment of lepromatous leprosy. ( Balakrishnan, S; Iyer, CG; Ramu, G, 1977) |
| "Dapsone/Creatinine in urine ratios were determined in statistically randomised samples of 965 leprosy patients attending out-patient department of Acworth Leprosy Hospital and 44 inmates of the Hospital." | 3.65 | Regularity of dapsone intake by leprosy patients attending urban treatment centre. ( Ganapati, R; Naik, SS, 1977) |
| "Serial observations on cutaneous sensation and on sweat response in hypopigmented flat patches of twenty-nine patients with tuberculoid and five with dimorphous leprosy on dapsone therapy were studied over 2 years." | 3.65 | The significance of the local sweat response in assessing the progress of leprosy. ( Sehgal, VN, 1976) |
| " Reactive episodes continue to be a serious complication, but the availability of thalidomide to control erythema nodosum leprosum has markedly improved the prognosis." | 3.65 | The diagnosis and treatment of leprosy. ( Jacobson, RR; Trautman, JR, 1976) |
| "Patients of lepromatous leprosy who have evolved from the borderline type of disease are known to revert to the borderline state through a reactionary phenomenon under anti-leprosy chemotherapy with Dapsone." | 3.65 | Transformation from lepromatous to borderline leprosy under clofazimine therapy. ( Mahapatra, SB; Ramu, G, 1976) |
| "A thirtyseven years old Hindu male of borderline lepromatous leprosy with reactions in the form of silvery white scales all over the body with scarring at places and greasy crusted lesion on the cheek further developed pustular reaction, after giving dapsone for a week, is reported." | 3.65 | Reactive episodes in borderline lepromatous leprosy--a case report. ( Acharya, PV; Agrawal, RV; Gupta, OP; Nigam, SP, 1976) |
| "This paper summarises our clinical experience with clofazimine in the treatment of 25 cases of reactive states of lepromatous and borderline leprosy and 7 lepromatous patients not responding to dapsone." | 3.65 | Clinical trial with clofazimine in leprosy. ( Dongre, VV; Ganapati, R, 1976) |
| "The level of dapsone in the blood 4 and 6 h after the ingestion of the 7th daily dose of 100 mg of the drug was investigated in 36 adult males with leprosy who had normal renal function and were free of diarrhoea and emesis." | 3.65 | Factors influencing the level of dapsone in blood. ( Beiguelman, B; El-Guindy, MM; Krieger, H; Pinto, W, 1974) |
| "Dapsone treated both bronchitis and COPD." | 3.30 | Bronchitis, COPD, and pneumonia after viral endemic of patients with leprosy on Sorok Island in South Korea. ( Altschuler, E; Bourbeau, J; Choi, SH; Coleman, M; Kanwar, B; Khattak, A; Lee, JH; Lee, SJ; Park, J; Sergi, C, 2023) |
| "The Clinical Trial for Uniform Multidrug Therapy for Leprosy Patients in Brazil (U-MDT/CT-BR), designed to evaluate the effectiveness of a six-months regimen, assessed the adverse effects caused by the drugs." | 2.87 | Clinical trial for uniform multidrug therapy for leprosy patients in Brazil (U-MDT/CT-BR): adverse effects approach. ( Bührer-Sékula, S; Cruz, RCDS; Gonçalves, HS; Moraes, MEA; Penna, GO; Penna, MLF; Pontes, MAA; Stefani, MMA; Talhari, S, 2018) |
| "Newly detected, treatment-naive leprosy patients were enrolled in India (six sites) and P." | 2.82 | International open trial of uniform multidrug therapy regimen for leprosy patients: Findings & implications for national leprosy programmes. ( Gupte, MD; Jadhav, V; Jamesh, A; Jianping, S; Kaliaperumal, K; Katoch, K; Krishnamurthy, P; Kutaiyan, R; Manickam, P; Mehendale, SM; Mugudalabetta, S; Nagaraju, B; Padma, J; Pannikar, V; Rajkumar, P, 2016) |
| "Incidence of neuritis associated with RR as well as isolated neuritis was similar in both groups." | 2.67 | Reversal reaction in multibacillary leprosy patients following MDT with and without immunotherapy with a candidate for an antileprosy vaccine, Mycobacterium w. ( Beena, KR; Kar, HK; Misra, RS; Mukherjee, A; Mukherjee, R; Nair, NS; Parida, SK; Sharma, AK; Walia, R; Zaheer, SA, 1993) |
| " In patients who received the same drug regimens but with a reduced dosage of ethionamide to 5 mg/k bodyweight, the incidence of hepatitis was significantly lower but the relapse rate was 7." | 2.67 | Treatment of multibacillary leprosy with a regimen of 13 weeks duration. ( Groenen, G; Janssens, L; Kuykens, L; Mputu, LB; Pattyn, SR, 1992) |
| " These preliminary results indicate that MDT is effective in treatment of paucibacillary leprosy, and also that clinical cure can be achieved in much shorter duration, particularly with higher dosage of rifampicin." | 2.67 | Multidrug therapy for treatment of paucibacillary leprosy in western Kenya--preliminary communications. ( Makokha, S; Nyawalo, J; Obura, M; Okelo, C; Okuku, P; Orege, PA, 1990) |
| "Dapsone has antimicrobial effects stemming from its sulfonamide-like ability to inhibit the synthesis of dihydrofolic acid." | 2.66 | Update on the use of dapsone in dermatology. ( Abbas, O; Ghaoui, N; Hanna, E; Kibbi, AG; Kurban, M, 2020) |
| "Leprosy is a chronic infectious disease caused my Mycobacterium leprae that primarily affects peripheral nervous system and extremities and is prevalent in tropical countries." | 2.66 | Metabolism and interactions of antileprosy drugs. ( George, J, 2020) |
| "Histoid leprosy is a rare variant of leprosy with a unique clinical presentation and bacilli rich histology." | 2.66 | Treatment of histoid leprosy: a lack of consensus. ( Bartos, G; Combs, A; Rivlin, D; Sheuring, R, 2020) |
| " The statistically significant difference between the two treatment groups indicates that, contrary to previous teaching, dapsone given in higher dosage does not predispose patients to reversal reactions and indeed may prevent them." | 2.64 | Evidence for prevention of borderline leprosy reactions by dapsone. ( Barnetson, RS; Pearson, JM; Rees, RJ, 1976) |
| "Dapsone prophylaxis has been shown to prevent secondary cases in contacts up to 25 years old and should be used in these and possibly in older persons." | 2.64 | Management of household contacts of leprosy patients. ( Filice, GA; Fraser, DW, 1978) |
| "Dapsone has been the main active principle in the multidrug regimen recommended by the World Health Organization for the treatment of leprosy." | 2.61 | Metabolic, pharmacokinetic, and toxicological issues surrounding dapsone. ( Brisigotti, V; Campanati, A; Molinelli, E; Offidani, A; Paolinelli, M, 2019) |
| "Dapsone is a sulfone drug used to treat infectious conditions and also numerous dermatologic diseases." | 2.55 | Dapsone-associated fixed drug eruption. ( Cohen, PR; Garcia, D, 2017) |
| "Leprosy is present in more than 100 countries, where it remains a major cause of peripheral neuropathy and disability." | 2.55 | Multidrug therapy for leprosy: a game changer on the path to elimination. ( Aerts, A; Kawuma, J; Kita, E; Saunderson, P; Smith, CS; Virmond, M, 2017) |
| "Leprosy is a chronic disease with many clinical manifestations, which affect mainly the skin, the peripheral nerves, mucosa of the upper respiratory tract and the eyes." | 2.53 | Leprosy – an old infectious disease with unsolved matters. ( Stock, I, 2016) |
| "Leprosy is an infectious disease that has now been reported for more than 2000 years." | 2.52 | Update on the epidemiology, diagnosis, and treatment of leprosy. ( Aubry, A; Cambau, E; Reibel, F, 2015) |
| "Leprosy has affected humans for millennia and remains an important health problem worldwide, as evidenced by nearly 250 000 new cases detected every year." | 2.48 | Current status of leprosy: epidemiology, basic science and clinical perspectives. ( Akama, T; Ishii, N; Kawashima, A; Suzuki, K; Yoshihara, A; Yotsu, RR, 2012) |
| "Leprosy is a granulomatous disease affecting the skin and peripheral nerves caused by Mycobacterium leprae." | 2.44 | [Hansen's disease: case report and review of literature]. ( Concha R, M; Cossio T, ML; Fich S, F; González B, S; Pérez C, C; Salazar S, I, 2008) |
| "Leprosy has definitely been present in China for at least 2,000 years." | 2.42 | Leprosy in China. ( Zhang, L, 2003) |
| "The diagnosis of leprosy is frequently not considered, with resultant pathological and psychological problems for patients." | 2.41 | Update on leprosy. ( Lockwood, DN; Marlowe, SN, 2001) |
| "Current treatment of leprosy involves use of 3 drugs: rifampicin (rifampin); clofazimine; and dapsone." | 2.41 | Leprosy. Recognition and treatment. ( Ramos-e-Silva, M; Rebello, PF, 2001) |
| "Pregnancy is not only a trigger factor for reaction but an ideal in vivo model for research." | 2.38 | An historical and clinical review of the interaction of leprosy and pregnancy: a cycle to be broken. ( Duncan, ME, 1993) |
| "Leprosy, also known as Hansen's disease, affects millions of people worldwide and is largely confined to the developing world." | 2.38 | Ocular leprosy. ( Schwab, IR, 1992) |
| "Cases of leprosy are increasing in the United States because of immigration from countries where the disease is endemic." | 2.37 | Leprosy presenting as peripheral neuropathy. ( Hale, WA, 1988) |
| "Leprosy (Hansen's disease) is a neglected tropical disease affecting millions of people globally." | 1.72 | Disease Burden and Current Therapeutical Status of Leprosy with Special Emphasis on Phytochemicals. ( Mahapatra, PK; Panda, SK; Sahoo, G; Swain, SS, 2022) |
| "Leprosy is a socially stigmatized granulomatous skin disease caused by Mycobacterium leprae." | 1.62 | The Clinical Trend of Leprosy from 2000 to 2016 in Kaohsiung, a Major International Harbor City in Taiwan, Where Leprosy is Almost Eradicated. ( Huang, HW; Lee, CH; Lin, SH, 2021) |
| "Leprosy is a stigmatizing, chronic infection which degenerates the nervous system and often leads to incapacitation." | 1.56 | Validation study of HLA-B*13:01 as a biomarker of dapsone hypersensitivity syndrome in leprosy patients in Indonesia. ( Irwan, ID; Irwanto, A; Krismawati, H; Liu, H; Liu, J; Maladan, Y; Oktavian, A; Pongtiku, A; Sitanggang, YA; Sun, Y; Tanjung, R; Wahyuni, T; Zhang, F, 2020) |
| "Dapsone resistance was found in 4 of 6 biopsies from American Samoa patients." | 1.48 | Dapsone Resistance in Leprosy Patients Originally from American Samoa, United States, 2010-2012. ( Araujo, S; Scollard, D; Stryjewska, BM; Williams, DL, 2018) |
| "Even with proper anti-mycobacteria treatment, leprosy follow up remains challenging: almost half of leprosy patients may develop reaction episodes." | 1.46 | Severe type 1 upgrading leprosy reaction in a renal transplant recipient: a paradoxical manifestation associated with deficiency of antigen-specific regulatory T-cells? ( Benard, G; de Paula, FJ; Duarte, AJDS; Lemos, FBC; Sakai-Valente, NY; Trindade, MAB; Vieira, AP, 2017) |
| "Hemolytic anemia is one of the complications related to the chronic consumption of dapsone." | 1.43 | Incidence and patterns of hemolytic anemia in acute dapsone overdose. ( Cha, K; Cha, YS; Hwang, SO; Kim, H; Kim, HI; Kim, J; Kim, OH; Lee, KH, 2016) |
| "To assess the adverse effects of multi drug therapy (MDT) in leprosy patients." | 1.37 | Adverse effects of multi-drug therapy in leprosy, a two years' experience (2006-2008) in tertiary health care centre in the tribal region of Chhattisgarh State (Bastar, Jagdalpur). ( Dey, V; Dulhani, N; Nel, B; Singh, H; Tiwari, P, 2011) |
| "Leprosy is a rare cause of neuropathy in Europeans." | 1.35 | [Sensory-motor neuropathy: a slow and misleading case of leprosy]. ( Andre, P; Camu, W; Flageul, B; Gabelle, A; Vallat, JM, 2008) |
| "After dapsone treatment appeared, leprosy control program has started." | 1.33 | [Leprosy situation in Myanmar before and after multidrug therapy]. ( Ishii, N; Mori, S, 2005) |
| "Leprosy is well controlled in Hong Kong but continued surveillance is required to detect relapses and to ensure good patient compliance with treatment." | 1.33 | Epidemiology of leprosy and response to treatment in Hong Kong. ( Ho, CK; Lo, KK, 2006) |
| "Leprosy is an ancient disease, which was treated by local application of chaulmoogra/hydnocarpus oil during prechemotherapeutic era." | 1.33 | Multidrug therapy in leprosy. ( Arif, MA; Manglani, PR, 2006) |
| "Areas of low endemicity of Hansen's disease, such as Texas, California, and Hawaii, exist due to immigration and rare autochthonous infections." | 1.32 | Short report: Treatment failure in Hansen's disease. ( Joyce, MP; Longfield, RN; Murray, CK, 2003) |
| "We report two cases of Hansen's disease." | 1.32 | [Two cases of Hansen's disease]. ( Horii, N; Ichikawa, E; Ishii, N; Koseki, M; Otsuka, F; Sugita, Y; Tanaka, M, 2003) |
| "falciparum malaria was known for many years, there was no report about the incidence of P." | 1.32 | Malaria, leprosy and dapsone. ( Arora, VM; Chattopadhya, D; Kapoor, L; Saha, K, 2003) |
| "Out of 34 leprosy patients undergoing treatment, 4 lepromatous leprosy patients were antibody positive, and 6." | 1.32 | Active surveillance of leprosy contacts in country with low prevalence rate. ( Abbasi, MA; Fukutomi, Y; Kai, M; Kashiwabara, Y; Khan, MZ; Kobayashi, K; Maeda, S; Maeda, Y; Makino, M; Shah, PA, 2004) |
| " The results of the study therefore reveal that patients undergoing therapy had significantly greater DNA damage than untreated patients, indicating bacterial infection and drug therapy as the causal factors, since lepromatous-type disease is the more severe form with the patients having lower resistance to Mycobacterium leprae and requiring heavier and prolonged dosage of antibiotics." | 1.32 | DNA damage studies in untreated and treated leprosy patients. ( Gandhi, G; Singh, B, 2004) |
| "It is the drug of choice for the treatment of leprosy and prophylaxis of malaria." | 1.30 | Haematological and biochemical alterations in leprosy patients already treated with dapsone and MDT. ( Barbosa, JC; de Carvalho, D; de Souza, AM; Gouveia, E; Melchior Júnior, E; Queiroz, RH, 1997) |
| "In the present study, we evaluated the in vivo anti-Mycobacterium leprae activities of KRM-1648 (KRM) given at long intervals in combination with ofloxacin (OFLX), clofazimine (CFZ), and dapsone (DDS)." | 1.30 | Studies on therapeutic activity of benzoxazinorifamycin KRM-1648 in combination with other antimicrobial agents and biological response modifiers interferon-gamma and granulocyte-macrophage colony-stimulating factor against M. leprae infection in athymic ( Maw, WW; Saito, H; Sato, K; Tomioka, H, 1997) |
| "Uncertainties about leprosy have led to a flexible design in which the user chooses which of many aspects should be included in the model." | 1.30 | SIMLEP: a simulation model for leprosy transmission and control. ( Gupte, MD; Habbema, JD; Meima, A; van Oortmarssen, GJ, 1999) |
| "In this study, the in vitro and in vivo anti-Mycobacterium leprae activity of the newly developed benzoxazinorifamycin, KRM-1648, in combination with clofazimine (CFZ) or dapsone (DDS) was evaluated." | 1.29 | Therapeutic efficacy of benzoxazinorifamycin, KRM-1648, in combination with other antimicrobials against Mycobacterium leprae infection induced in nude mice. ( Dekio, S; Saito, H; Sato, K; Tomioka, H, 1994) |
| "The problem of leprosy is to be properly assessed throughout the Indian subcontinent because most of the epidemiological data from the areas labeled low-endemic have to be updated." | 1.28 | Multidrug therapy in multibacillary leprosy; experience in an urban leprosy center. ( Misra, RS; Ramesh, V; Saxena, U, 1992) |
| "Lymphocytes of untreated leprosy patients showed a low mitotic index and a slow rate of cell proliferation." | 1.28 | Cytogenetic studies in leprosy patients before and after chemotherapy. ( D'Souza, D; Das, BC; Thomas, IM, 1991) |
| "Leprosy is essentially found in rural areas and frequently causes disabilities." | 1.28 | [Endemic leprosy in the People's Republic of Congo. An epidemiological and behavioral analysis]. ( Baya-Tsika, N; Coddy-Zitsamele, R; Cottenot, F; Eozenou, P; Gelas, H; Hengy, C; Jannin, J; Louis, JP; Obvala, D; Trebucq, A, 1990) |
| "The antibacterial effect of brodimoprim alone and in combination with dapsone has been studied in vitro in cell-free systems and in whole mycobacterial cells as well as in vivo in mice and humans." | 1.28 | In vitro and in vivo experiments with the new inhibitor of mycobacterium leprae brodimoprim alone and in combination with dapsone. ( Dhople, AM; Jagannathan, R; Mahadevan, PR; Rosenfeld, M; Seydel, JK; Wempe, EG, 1990) |
| "Dapsone treated group showed a disability rate of 63." | 1.28 | Pattern of leprosy disabilities in Gorakhpur (Uttar Pradesh). ( Arora, SK; Girdhar, M; Mohan, L; Mukhija, RD, 1989) |
| "Dapsone treatment cleared her skin lesion, but did not remove the paraesthesia in the right ulnar nerve." | 1.27 | Leprosy in Vietnamese refugees: a case report. ( Christiansen, JV; Jensen, JR; Søgård, H; Thestrup-Pedersen, K, 1983) |
| "Treatment with dapsone resulted in clearing of the skin in both cases." | 1.27 | [Dimorphous leprosy]. ( Esca, SA; Zelger, J, 1984) |
| " ratios in the spot test negative urine specimens were consistent for all dosage groups and ranged from 7." | 1.27 | Paper spot test and DDS/creatinine ratios in relation to treatment taken by leprosy patients. ( Balakrishnan, S; Kumar, A; Rozario, JA; Sirumban, P; Thiagarajan, M, 1983) |
| "Five patients with leprosy are presented." | 1.27 | Leprosy in five armadillo handlers. ( Cox, GF; Lumpkin, LR; Wolf, JE, 1983) |
| "Clofazimine was administered in different doses over a period of 12 months." | 1.27 | The effect of clofazimine on liver function tests in lepra reaction (ENL). ( Bulakh, PM; Burte, NP; Chandorkar, AG; Kowale, CN; Ranade, SM, 1983) |
| "These results lead to an impairment of Hansen's disease neuropathy during DDS therapy affecting the motor conduction velocities of one quarter of the patients, and are discussed in terms of physiopathological mechanisms." | 1.27 | Dapsone-induced neuropathy compounds Hansen's disease nerve damage: an electrophysiological study in tuberculoid patients. ( Chevallard, A; Cordoliani, G; Nebout, M; Raffalli, MJ; Sebille, A, 1987) |
| " The treatment of mice with the smaller dosage ofloxacin, with pefloxacin, prothionamide, or dapsone uniformly resulted in a delay of multiplication of 4 months, compared to the multiplication of M." | 1.27 | Activity of ofloxacin against Mycobacterium leprae in the mouse. ( Beoletto, C; Grosset, JH; Guelpa-Lauras, CC; Perani, EG, 1988) |
| "Two cases of tuberculoid leprosy with primary hyperpigmented anaesthetic lesions are reported and subject is reviewed." | 1.27 | Primary hyperpigmented cutaneous lesions in tuberculoid leprosy. ( Chattopadhyay, SP; Gupta, CM, 1988) |
| ""Relapse" was defined as the reappearance of Mycobacterium leprae in skin smears." | 1.27 | Relapse rates in lepromatous leprosy according to treatment regularity. ( Almeida, JG; Chacko, CJ; Christian, M; Jesudasan, K, 1986) |
| "Leprosy is a major health hazard in tropical countries as it also is in China." | 1.27 | Leprosy control by a people's program: "a new concept in technology transfer". ( Antia, NH, 1987) |
| " ENL was also more frequent in regimens C and D and was not prevented by CLO in the dosage used." | 1.27 | Prospective study on the relationship between intensive bactericidal therapy and leprosy reactions. ( Coussens, L; Groenen, G; Janssens, L; Kayembe, T; Nollet, E; Pattyn, SR, 1986) |
| "Only in lepromatous cases was complete ageusia seen (9." | 1.27 | Electrogustometry in Hansen's disease (study of 225 cases). ( Chaturvedi, VN; Jain, SK; Raizada, RM; Rathi, SS, 1986) |
| "A leprosy patient who developed acute renal failure on multidrug therapy is reported." | 1.27 | Acute renal failure--a complication of new multidrug regimen for treatment of leprosy. ( Acharya, VM; Almeida, AF; Dedhia, NM; Khanna, UB; Mittal, BV, 1986) |
| "Leprosy is a widely distributed infectious disease in countries with tropic or subtropic climate and the most frequent treatable polyneuropathy." | 1.27 | [Pathomorphology of leprosy]. ( King, R; Thomas, PK; Warzok, R, 1986) |
| "A search for structural and numerical chromosomal aberrations was made on metaphases obtained by culturing in vitro skin fibroblasts of 16 leprosy patients (10 lepromatous, 2 borderline, and 4 tuberculoid cases) and 2 healthy individuals used as controls." | 1.27 | Chromosomal aberrations in cultures of skin fibroblasts of leprosy patients. ( Beiguelman, B; Hackel, C, 1985) |
| "Lymphocytes from patients with untreated lepromatous leprosy failed to respond to the M." | 1.26 | In vitro lymphocyte stimulation in patients with lepromatous and borderline tuberculoid leprosy. The effect of dapsone treatment on the response to Mycobacterium leprae antigens, tuberculin purified protein derivative and non-mycobacterial stimulants. ( Belehu, A; Closs, O; Reitan, LJ, 1982) |
| "Most of the patients preferred to take treatment at leprosy referral hospitals." | 1.26 | Illness and service utilization behaviours of leprosy patients. ( Anbalagan, M; Kumar, A, 1982) |
| "Leprosy is a rare disease in Bulgaria." | 1.26 | [Leprosy in Bulgaria. Epidemiology, Clinical forms and treatment (author's transl)]. ( Dimitrova, I; Mikhailov, P, 1981) |
| " Although the sera varied in potency, they showed similar dose-response curves when tested against lymphocytes from a single donor." | 1.26 | Serum inhibitory factor in lepromatous leprosy: its effect on the pre-S-phase cell-cycle kinetics of mitogen-stimulated normal human lymphocytes. ( Beck, JS; Brown, RA; Gibbs, JH; Potts, RC; Robertson, AJ; Sherif, MM, 1981) |
| " The results revealed that the strain, SR61-L74, was almost completely resistant to DDS, and responded only to the long-term administration of Streptomycin and Isoniazid." | 1.26 | In vitro resistance test of human leprosy bacilli to anti-leprous drugs. ( Fujuda, T; Hagiwara, S; Ishihara, S, 1977) |
| " The initial dosage of either of the drugs was 300 mg daily administered in divided doses of 100 mg three times a day." | 1.26 | Treatment of steroid dependant cases of recurrent lepra reaction with a combination of thalidomide and clofazimine. ( Girdhar, A; Ramu, G, 1979) |
| "The patient denied a history of Hansen's disease, despite the dermatologic and facial features that suggested the diagnosis." | 1.26 | Lepromatous iridocyclitis diagnosed by anterior chamber paracentesis. ( Michelson, JB; Roth, AM; Waring, GO, 1979) |
| " The subjects of this study were receiving dapsone at the daily dosage of 25, 50 and 100 mg or bi-weekly dosage of 25, 50, 75, 100 and 200 mgs." | 1.26 | Monitoring self administration of dapsone by patients. ( Balakrishnan, S, 1977) |
| "Hodgkin's disease was diagnosed 14 months after the complete disappearance of mycobacterium leprae from the skin lesions, under treatment with DDS (diamino-diphenyl-sulfone)." | 1.26 | Development of Hodgkin's disease in a patient with leprosy. ( Gordon, R; Kopolovic, J; Leviatan, A; Weshler, Z, 1978) |
| " Treatment with the smaller dosage of dapsone neither killed M." | 1.26 | Dapsone chemotherapy of Mycobacterium leprae infection of the neonatally thymectomized Lewis rat. ( Fieldsteel, AH; Levy, L, 1976) |
| " The Urine D/C ratio was estimated in 35 patients who were receiving a supervised daily dosage of either 50 or 100 mgs of DDS." | 1.26 | An evaluation of the self administration of DDS in Gudiyatham Taluk. ( Chacko, CJ; George, B; Jesudasan, K; Job, CK; Kurian, PV; Taylor, PM, 1976) |
| " The common side effect in all cases consisted of red and dark skin pigmentation of varying intensity occuring within 10 weeks of the commencement of therapy." | 1.26 | Side effects of clofazimine therapy. ( Iyer, GG; Ramu, G, 1976) |
| " Low dosage favoured the appearance of resistance; therefore regular treatment of lepromatous leprosy with dapsone in full dosage is recommended." | 1.25 | Sulphone resistance in leprosy. A review of one hundred proven clinical cases. ( Pearson, JM; Rees, RJ; Waters, MF, 1975) |
| "The necessity for early diagnosis and treatment of leprosy in the absence of an effective vaccine is discussed and the pathological changes that occur in the nose are outlined." | 1.25 | Importance of nasal lesions in early lepromatous leprosy. ( Barton, RP, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 780 (72.36) | 18.7374 |
| 1990's | 118 (10.95) | 18.2507 |
| 2000's | 81 (7.51) | 29.6817 |
| 2010's | 71 (6.59) | 24.3611 |
| 2020's | 28 (2.60) | 2.80 |
| Authors | Studies |
|---|---|
| Bera, S | 1 |
| Mondal, D | 1 |
| Swain, SS | 2 |
| Sahoo, G | 1 |
| Mahapatra, PK | 1 |
| Panda, SK | 1 |
| Chakraborty, A | 1 |
| Ghosh, R | 1 |
| Biswas, A | 1 |
| Frade, MAC | 1 |
| Bernardes Filho, F | 1 |
| Lima, ALQ | 1 |
| Menezes, MB | 1 |
| Lugão, HB | 1 |
| Andrade, ESN | 1 |
| Brandão, JG | 1 |
| Silva, JSD | 1 |
| Coriolano, CRF | 1 |
| Rosa, PS | 4 |
| Moraes, MO | 2 |
| Ferreira, CO | 1 |
| Gomes, CM | 2 |
| Araújo, WN | 1 |
| Sapra, D | 1 |
| Singh, GK | 1 |
| Bahuguna, A | 1 |
| Das, P | 2 |
| Gupta, A | 1 |
| Krismawati, H | 3 |
| Ferdiana, A | 1 |
| Irwanto, A | 4 |
| Budiawan, T | 1 |
| Imaniar, C | 1 |
| Wahyuni, T | 2 |
| Singh, P | 1 |
| Mieras, L | 1 |
| Pongtiku, A | 2 |
| Wu, Z | 1 |
| Wang, C | 5 |
| Wang, Z | 3 |
| Shi, Y | 1 |
| Jiang, H | 1 |
| Wang, H | 4 |
| Ahuja, M | 2 |
| Singh, I | 4 |
| Lavania, M | 2 |
| Pathak, VK | 1 |
| Darlong, J | 1 |
| Turankar, RP | 1 |
| Hembrom, S | 1 |
| Singh, SV | 1 |
| Sengupta, U | 4 |
| Marijke Braet, S | 1 |
| Jouet, A | 2 |
| Aubry, A | 2 |
| Van Dyck-Lippens, M | 1 |
| Lenoir, E | 2 |
| Assoumani, Y | 2 |
| Baco, A | 1 |
| Mzembaba, A | 1 |
| Cambau, E | 5 |
| Vasconcellos, SEG | 1 |
| Rigouts, L | 1 |
| Suffys, PN | 2 |
| Hasker, E | 2 |
| Supply, P | 2 |
| de Jong, BC | 2 |
| Khalilzadeh, M | 1 |
| Shayan, M | 1 |
| Jourian, S | 1 |
| Rahimi, M | 1 |
| Sheibani, M | 1 |
| Dehpour, AR | 1 |
| Li, X | 1 |
| Li, G | 1 |
| Yang, J | 5 |
| Jin, G | 1 |
| Shao, Y | 1 |
| Li, Y | 2 |
| Wei, P | 1 |
| Zhang, L | 3 |
| Muddebihal, A | 1 |
| Sardana, K | 1 |
| Khurana, A | 1 |
| Sachdeva, S | 2 |
| Sharma, R | 3 |
| Matsubara, S | 2 |
| Lee, JH | 2 |
| Kanwar, B | 1 |
| Khattak, A | 1 |
| Altschuler, E | 1 |
| Sergi, C | 1 |
| Lee, SJ | 1 |
| Choi, SH | 1 |
| Park, J | 1 |
| Coleman, M | 1 |
| Bourbeau, J | 1 |
| Kong, J | 1 |
| Li, B | 1 |
| Ji, Z | 1 |
| Liu, A | 1 |
| Chen, J | 2 |
| Liu, M | 2 |
| Fan, Y | 1 |
| Peng, L | 1 |
| Song, J | 1 |
| Wu, X | 1 |
| Gao, L | 1 |
| Ma, W | 1 |
| Dong, Y | 1 |
| Luo, S | 1 |
| Bao, F | 2 |
| Braet, SM | 1 |
| Gaudin, C | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety Study of Immunomodulator (Mycobacterium w) as an Adjunct Therapy in Category-II Pulmonary Tuberculosis Along With Assessment of Immunological Parameters[NCT00265226] | Phase 3 | 1,020 participants (Actual) | Interventional | 2005-03-31 | Completed | ||
| Efficacy and Safety of Immunomodulator (Mycobacterium w.) as an Adjunct Therapy in Category I Pulmonary Tuberculosis and Along With Assessment of Immunological Parameters[NCT00341328] | Phase 3 | 300 participants (Actual) | Interventional | 2007-03-31 | Completed | ||
| Independent Study to Establish the Efficacy of the Six Doses Uniform MDT Regimen (U-MDT) for Leprosy Patients[NCT00669643] | Phase 4 | 859 participants (Actual) | Interventional | 2007-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
80 reviews available for dapsone and Hansen Disease
| Article | Year |
|---|---|
Insights of synthetic analogues of anti-leprosy agents.
Topics: Humans; Leprostatic Agents; Leprosy; Structure-Activity Relationship | 2019 |
Risk factors for dapsone resistance in leprosy patients: a systematic meta-analysis.
Topics: Dapsone; Humans; Leprosy; Mycobacterium leprae; Recurrence; Risk Factors | 2022 |
A comprehensive insight into the anti-inflammatory properties of dapsone.
Topics: Anti-Inflammatory Agents; Antioxidants; Dapsone; Humans; Leprosy; Reactive Oxygen Species | 2022 |
Drug Resistance (Dapsone, Rifampicin, Ofloxacin) and Resistance-Related Gene Mutation Features in Leprosy Patients: A Systematic Review and Meta-Analysis.
Topics: Amino Acids; Dapsone; Drug Resistance, Bacterial; Humans; Leprostatic Agents; Leprosy; Microbial Sen | 2022 |
Seventy years of evidence on the efficacy and safety of drugs for treating leprosy: a network meta-analysis.
Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy; Leprosy, Multi | 2023 |
Update on the use of dapsone in dermatology.
Topics: Acne Vulgaris; Anti-Infective Agents; Anti-Inflammatory Agents; Dapsone; Dermatitis Herpetiformis; D | 2020 |
Metabolism and interactions of antileprosy drugs.
Topics: Acedapsone; Biological Availability; Biotransformation; Clofazimine; Cytochrome P-450 CYP3A; Dapsone | 2020 |
Treatment of histoid leprosy: a lack of consensus.
Topics: Clofazimine; Consensus; Dapsone; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy | 2020 |
Dapsone-associated fixed drug eruption.
Topics: Anti-Infective Agents; Dapsone; Dermatologic Agents; Diagnosis, Differential; Drug Eruptions; Humans | 2017 |
An Employee With Undiagnosed Leprosy: Are Other Employees at Risk?
Topics: Dapsone; Diagnosis, Differential; Humans; Leprostatic Agents; Leprosy; Male; Middle Aged; Mycobacter | 2017 |
Multidrug therapy for leprosy: a game changer on the path to elimination.
Topics: Clofazimine; Dapsone; Disease Eradication; Drug Therapy, Combination; Humans; Leprostatic Agents; Le | 2017 |
Leprosy – an old infectious disease with unsolved matters.
Topics: Animals; Armadillos; Clofazimine; Cross-Sectional Studies; Dapsone; Disease Reservoirs; Drug Therapy | 2016 |
Metabolic, pharmacokinetic, and toxicological issues surrounding dapsone.
Topics: Animals; Anti-Infective Agents; Dapsone; Drug Interactions; Humans; Leprostatic Agents; Leprosy; Ski | 2019 |
Update on the epidemiology, diagnosis, and treatment of leprosy.
Topics: Antibodies, Bacterial; Bacteriological Techniques; Biopsy; Clofazimine; Dapsone; Drug Resistance, Ba | 2015 |
A Review on Dapsone Hypersensitivity Syndrome Among Chinese Patients with an Emphasis on Preventing Adverse Drug Reactions with Genetic Testing.
Topics: Adolescent; Adult; Aged; Alleles; Child; China; Dapsone; Drug Hypersensitivity; Drug Substitution; F | 2017 |
Arthritis in leprosy.
Topics: Arthritis; Clofazimine; Dapsone; Diagnosis, Differential; Humans; Leprostatic Agents; Leprosy; Mycob | 2010 |
A short history of dapsone, or an alternative model of drug development.
Topics: Antimalarials; Dapsone; Drug Industry; History, 20th Century; Humans; Leprostatic Agents; Leprosy; M | 2011 |
Current status of leprosy: epidemiology, basic science and clinical perspectives.
Topics: Animals; Dapsone; Drug Therapy, Combination; Female; Humans; Leprostatic Agents; Leprosy; Male; Myco | 2012 |
Leprosy.
Topics: Bacterial Vaccines; BCG Vaccine; Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Leprosy; M | 2002 |
[Leprosy].
Topics: Dapsone; Diagnosis, Differential; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy; My | 2003 |
Leprosy in China.
Topics: China; Communicable Disease Control; Dapsone; Government Programs; Humans; Incidence; Leprostatic Ag | 2003 |
[DNA microarray based rapid drug susceptibility test for Mycobacterium leprae].
Topics: Animals; Dapsone; Drug Resistance, Microbial; Humans; Leprostatic Agents; Leprosy; Mice; Microbial S | 2006 |
[Leprosy and medicine II--progress and establishment of an absolute isolation policy].
Topics: Dapsone; Europe; Hawaii; Humans; Japan; Leprosy; Mycobacterium leprae; Patient Isolation | 2007 |
A overview of ocular leprosy after 2 decades of multidrug therapy.
Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Eye Infections, Bacterial; Global Health; Humans; L | 2007 |
[Hansen's disease: case report and review of literature].
Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy; Male; Middle A | 2008 |
The neurotoxicity of dapsone.
Topics: Adolescent; Adult; Animals; Child; Dapsone; Dermatitis Herpetiformis; Electrophysiology; Female; Gui | 1984 |
Bacteriology of Mycobacterium leprae.
Topics: Animals; Antigens, Bacterial; Cell Wall; Dapsone; DNA, Bacterial; Drug Resistance, Microbial; Immuno | 1983 |
Evolution of the modern chemotherapy of leprosy.
Topics: Animals; Clofazimine; Dapsone; Drug Evaluation; Drug Evaluation, Preclinical; Drug Resistance, Micro | 1983 |
Recent changes in leprosy control.
Topics: Bacterial Vaccines; Clofazimine; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mycobacterium | 1983 |
The immunopharmacology of antileprosy agents.
Topics: Antigens, Bacterial; Clofazimine; Dapsone; Erythema Nodosum; Humans; Immune Tolerance; Immunity, Cel | 1983 |
Leprosy (Hansen's disease).
Topics: Clofazimine; Dapsone; Ear Deformities, Acquired; Humans; Leprosy; Mouth Diseases; Nose Deformities, | 1982 |
Sulfonamides and sulfones in dermatologic therapy.
Topics: Animals; Chancroid; Conjunctivitis, Inclusion; Dapsone; Dermatitis Herpetiformis; Erythrocytes; Gluc | 1981 |
Patient compliance with dapsone administration in leprosy.
Topics: Africa; Animals; Bacterial Infections; Dapsone; History, 20th Century; Humans; India; Leprosy; Niger | 1981 |
Drug compliance in the treatment of leprosy.
Topics: Dapsone; Humans; Leprostatic Agents; Leprosy; Patient Compliance | 1981 |
In vitro and in vivo results of brodimoprim and analogues alone and in combination against E. coli and mycobacteria.
Topics: Dapsone; Dihydropteroate Synthase; Escherichia coli; Escherichia coli Infections; Humans; Leprosy; M | 1993 |
An historical and clinical review of the interaction of leprosy and pregnancy: a cycle to be broken.
Topics: Adult; Breast Feeding; Dapsone; Developing Countries; Female; History, 20th Century; History, Ancien | 1993 |
Dapsone agranulocytosis in a leprosy patient.
Topics: Adult; Agranulocytosis; Dapsone; Female; Humans; Leprostatic Agents; Leprosy | 1994 |
Hansen's disease (leprosy).
Topics: Adult; Dapsone; Humans; Leprostatic Agents; Leprosy; Male; Nebraska | 1996 |
[Synthesis of promin in Japan and global elimination of Hansen's disease].
Topics: Dapsone; Financial Support; Humans; International Cooperation; Japan; Leprostatic Agents; Leprosy; R | 1997 |
The impact of multiple drug therapy on leprosy disabilities.
Topics: Clinical Trials as Topic; Dapsone; Disabled Persons; Drug Therapy, Combination; Humans; Leprostatic | 1997 |
Chemoprophylaxis is effective in the prevention of leprosy in endemic countries: a systematic review and meta-analysis. MILEP2 Study Group. Mucosal Immunology of Leprosy.
Topics: Acedapsone; Clinical Trials as Topic; Cost-Benefit Analysis; Dapsone; Humans; Leprostatic Agents; Le | 2000 |
Dapsone and sulfapyridine.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Dapsone; Dermatologic Agents; Humans | 2001 |
Update on leprosy.
Topics: Clofazimine; Dapsone; Diagnosis, Differential; Drug Therapy, Combination; Humans; Leprostatic Agents | 2001 |
Leprosy.
Topics: Clofazimine; Cost-Benefit Analysis; Dapsone; Drug Therapy, Combination; Global Health; Humans; Inter | 2001 |
Leprosy. Recognition and treatment.
Topics: Adolescent; Adult; Age Factors; Biopsy; Child; Clinical Trials as Topic; Clofazimine; Dapsone; Diagn | 2001 |
Leprosy reactional states and their treatment.
Topics: Antigen-Antibody Complex; Clofazimine; Dapsone; Humans; Immunity, Cellular; Leprosy; Prednisolone; T | 1977 |
[Progress in leprology in recent years].
Topics: Animals; Dapsone; Dihydroxyphenylalanine; Disease Models, Animal; Humans; L-Lactate Dehydrogenase; L | 1975 |
Chemotherapy in Leprosy.
Topics: Acetamides; Anemia, Hemolytic; Aniline Compounds; Animals; Clofazimine; Dapsone; Disease Models, Ani | 1975 |
[Leprosy therapy and pharmacogenetics (author's transl)].
Topics: Acetyltransferases; Clofazimine; Cytochrome-B(5) Reductase; Dapsone; Glucosephosphate Dehydrogenase; | 1975 |
Ocular leprosy.
Topics: Anti-Bacterial Agents; Blindness; Dapsone; Eye Infections, Bacterial; Humans; Leprosy | 1992 |
Relapses among leprosy patients treated with multidrug therapy: experience in the leprosy control program of the All Africa Leprosy and Rehabilitation Training Center (ALERT) in Ethiopia; practical difficulties with diagnosing relapses; operational proced
Topics: Clofazimine; Dapsone; Epidemiologic Methods; Ethiopia; Humans; Incidence; Leprostatic Agents; Lepros | 1992 |
Duration of multidrug therapy in paucibacillary leprosy patients; experience in the leprosy control program of the All Africa Leprosy and Rehabilitation Training Center (ALERT) in Ethiopia.
Topics: Dapsone; Drug Therapy, Combination; Ethiopia; Humans; Leprosy; Leprosy, Borderline; Leprosy, Leproma | 1992 |
Therapeutic regimens in leprosy.
Topics: Anti-Bacterial Agents; Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lep | 1990 |
Pharmacochemical aspects of leprosy. Recent developments and prospects for new drugs.
Topics: Dapsone; Humans; Leprostatic Agents; Leprosy; Mycobacterium leprae; Rifampin | 1989 |
Leprosy presenting as peripheral neuropathy.
Topics: Adult; Dapsone; Drug Therapy, Combination; Humans; Leprosy; Male; Peripheral Nervous System Diseases | 1988 |
Chemotherapy of leprosy.
Topics: Clofazimine; Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leprosy; Rifa | 1988 |
Etiological factors in delayed-type hypersensitivity reactions in leprosy.
Topics: Antigens, Bacterial; Dapsone; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Interferon-gamm | 1987 |
The management of leprosy.
Topics: Child; Dapsone; Drug Resistance, Microbial; Humans; Leprostatic Agents; Leprosy | 1987 |
The management of reactions in leprosy.
Topics: Dapsone; Dermatitis; Erythema Nodosum; Female; Humans; Leprosy; Neuritis; Pregnancy | 1987 |
Screening of drugs for activity against Mycobacterium leprae.
Topics: Animals; Clofazimine; Dapsone; Drug Evaluation, Preclinical; Leprostatic Agents; Leprosy; Mice; Myco | 1987 |
Pharmacokinetics in drug screening.
Topics: Animals; Biological Availability; Body Weight; Dapsone; Drug Evaluation, Preclinical; Humans; Lepros | 1987 |
The immunobiology of leprosy.
Topics: Animals; Antigens, Bacterial; Dapsone; Drug Resistance; Genetic Linkage; HLA Antigens; Humans; Immun | 1986 |
Drug resistance in leprosy--a review.
Topics: Animals; Clofazimine; Dapsone; Drug Resistance, Microbial; Ethionamide; Humans; Leprosy; Mice; Micro | 1985 |
Comments on the chemotherapy of leprosy as influenced by present knowledge of Mycobacterium leprae.
Topics: Aniline Compounds; Dapsone; Drug Resistance, Microbial; Ethionamide; Humans; Leprosy; Mycobacterium | 1973 |
Growing points in leprosy research. 4. Recent advances in the chemotherapy of leprosy.
Topics: Clofazimine; Dapsone; Ethionamide; Humans; Leprosy; Rifampin; Sulfonamides; Thioacetazone; Thiourea | 1974 |
The evaluation of present antileprosy compounds.
Topics: Animals; Anti-Bacterial Agents; Clinical Trials as Topic; Dapsone; Disease Models, Animal; Drug Resi | 1969 |
[New methods of experimental chemotherapy in leprosy].
Topics: Aminobenzoates; Animals; Culture Techniques; Dapsone; Ethambutol; Isoniazid; Leprosy; Mice; Mycobact | 1969 |
Recent advances in experimental leprosy.
Topics: Africa; Animals; BCG Vaccine; Dapsone; Disease Models, Animal; Humans; Independent State of Samoa; I | 1970 |
Summary of recent abstracts. 8. Leprosy.
Topics: Animals; Antibody Formation; BCG Vaccine; Dapsone; Disease Models, Animal; Guinea Pigs; Humans; Lepr | 1970 |
Neurosurgical aspects of leprosy.
Topics: Abscess; Adolescent; Adult; Aged; Brain; Carpal Tunnel Syndrome; Child; Dapsone; Demyelinating Disea | 1974 |
Recent trends in leprosy research.
Topics: Animals; Clinical Trials as Topic; Dapsone; Foot; Humans; Immunoglobulins; Leprosy; Lymph Nodes; Mic | 1972 |
New perspectives on the chemotherapy of malaria, filariasis, and leprosy.
Topics: Amodiaquine; Aniline Compounds; Antimalarials; Chloroquine; Cresols; Dapsone; Drug Resistance; Filar | 1974 |
[Present-day specific therapeutic drugs for leprosy].
Topics: Dapsone; Female; Humans; Leprosy; Male; Oils; Sulfadimethoxine; Sulfamethoxypyridazine; Sulfanilamid | 1966 |
Chemotherapy of leprosy.
Topics: Animals; Anti-Bacterial Agents; Chemical Phenomena; Chemistry; Dapsone; Delayed-Action Preparations; | 1969 |
Leprosy.
Topics: Adult; Animals; Child; Child, Preschool; Dapsone; Female; Humans; Leprosy; Mice; Pregnancy | 1969 |
New prospects for the study of leprosy in the laboratory.
Topics: Animals; Animals, Laboratory; Anti-Bacterial Agents; Bacteriological Techniques; Culture Techniques; | 1969 |
The evaluation of present antileprosy compounds.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; BCG Vaccine; Clinical Trials as Topic; Dapson | 1969 |
Recent advances in the study of the leprosy bacillus.
Topics: Animals; Cricetinae; Dapsone; Drug Resistance, Microbial; Humans; Isoniazid; Leprosy; Mice; Microbia | 1969 |
Summary of recent abstracts. 8. Leprosy.
Topics: Animals; Dapsone; Disease Models, Animal; Humans; Leprosy; Mice; Phenazines; Thalidomide | 1971 |
The first decade in experimental leprosy.
Topics: Animals; BCG Vaccine; Clofazimine; Dapsone; Disease Models, Animal; Drug Evaluation; Drug Evaluation | 1971 |
103 trials available for dapsone and Hansen Disease
| Article | Year |
|---|---|
Bronchitis, COPD, and pneumonia after viral endemic of patients with leprosy on Sorok Island in South Korea.
Topics: Acetylcholine; Bronchitis; Dapsone; Dementia; Humans; Leprosy; Pneumonia; Pulmonary Disease, Chronic | 2023 |
Clinical trial for uniform multidrug therapy for leprosy patients in Brazil (U-MDT/CT-BR): adverse effects approach.
Topics: Adolescent; Adult; Anemia; Brazil; Child; Clofazimine; Dapsone; Drug Therapy, Combination; Female; H | 2018 |
International open trial of uniform multidrug therapy regimen for leprosy patients: Findings & implications for national leprosy programmes.
Topics: Adolescent; Adult; Aged; Child; China; Dapsone; Drug Therapy, Combination; Female; Humans; India; Le | 2016 |
Plasma levels of chemokines during leprosy specific treatment.
Topics: Adult; Aged; Chemokine CCL11; Chemokine CCL24; Chemokines; Clofazimine; Dapsone; Drug Therapy, Combi | 2010 |
Biochemical and hematological side effects of clofazimine in leprosy patients.
Topics: Blood Cell Count; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Leprostatic Agent | 2002 |
Parallel assessment of 24 monthly doses of rifampin, ofloxacin, and minocycline versus two years of World Health Organization multi-drug therapy for multi-bacillary leprosy.
Topics: Adolescent; Adult; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Leprostatic Agen | 2004 |
International open trial of uniform multi-drug therapy regimen for 6 months for all types of leprosy patients: rationale, design and preliminary results.
Topics: Adolescent; Adult; Aged; Child; China; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Huma | 2008 |
Once-monthly rifampicin plus daily dapsone in initial treatment of lepromatous leprosy.
Topics: Adolescent; Adult; Aged; Child; Clinical Trials as Topic; Dapsone; Drug Therapy, Combination; Female | 1982 |
THELEP controlled clinical trials in lepromatous leprosy.
Topics: Animals; Clinical Trials as Topic; Clofazimine; Dapsone; Female; Humans; Leprostatic Agents; Leprosy | 1983 |
[Field experiences with therapy protocols in leprosy].
Topics: Clinical Trials as Topic; Clofazimine; Dapsone; Drug Administration Schedule; Humans; Leprostatic Ag | 1983 |
Hepatotoxicity of the combination of rifampin-ethionamide in the treatment of multibacillary leprosy.
Topics: Adolescent; Adult; Chemical and Drug Induced Liver Injury; Child; Clinical Trials as Topic; Clofazim | 1984 |
Relapse rates among nonlepromatous patients released from control.
Topics: Adolescent; Adult; Child; Clinical Trials as Topic; Dapsone; Female; Humans; Leprosy; Male; Recurren | 1984 |
[Initial results of prospective controlled treatment trials in leprosy].
Topics: Adolescent; Adult; Clinical Trials as Topic; Dapsone; Female; Humans; Leprosy; Male; Middle Aged; Pr | 1984 |
Multidrug therapy for leprosy in Trinidad and Tobago: a preliminary report.
Topics: Acedapsone; Adolescent; Adult; Aged; Child; Child, Preschool; Clinical Trials as Topic; Clofazimine; | 1984 |
[Pilot-trial of treatment of leprosy by pig's thymosin combined with dapsone (author's transl)].
Topics: Adult; Clinical Trials as Topic; Dapsone; Drug Therapy, Combination; Female; Humans; Leprosy; Male; | 1981 |
Effect of epicondylectomy in early ulnar neuritis treated with steroids.
Topics: Acetaminophen; Dapsone; Humans; Leprosy; Neuritis; Prednisolone; Ulnar Nerve; Vitamin B Complex | 1984 |
Chemoprophylaxis against leprosy with acedapsone.
Topics: Acedapsone; Adolescent; Age Factors; Child; Child, Preschool; Dapsone; Female; Humans; Infant; Lepro | 1983 |
Effect of levamisole on clinical outcome and DNCB conversion in leprosy patients. A long term study.
Topics: Dapsone; Dinitrochlorobenzene; Humans; Immunity, Cellular; Immunization; Leprosy; Levamisole; Nitrob | 1983 |
Controlled comparison of therapeutic effects of DDS in combination with daily or once-monthly rifampicin in patients with lepromatous leprosy.
Topics: Adolescent; Adult; Child; Clinical Trials as Topic; Dapsone; Drug Therapy, Combination; Female; Huma | 1981 |
Intermittent rifampicin therapy in lepromatous leprosy.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Clinical Trials as Topic; Dapsone; Doubl | 1980 |
Chemoprophylaxis against leprosy with acedapsone. An interim report.
Topics: Acedapsone; Adolescent; Age Factors; Child; Child, Preschool; Clinical Trials as Topic; Dapsone; Dou | 1980 |
Fluorimetric screening of dapsone in urine for drug trials.
Topics: Clinical Trials as Topic; Colorimetry; Creatinine; Dapsone; Humans; Leprosy; Spectrometry, Fluoresce | 1980 |
Report of the Third Meeting of the Scientific Working Group on Chemotherapy of Leprosy (THELEP) of the UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases, Geneva, 20-22 October 1980.
Topics: Animals; Clinical Trials as Topic; Dapsone; Drug Resistance, Microbial; Global Health; Humans; Lepro | 1981 |
A controlled trial to compare the therapeutic effects of dapsone in combination with daily or once-monthly rifampin in patients with lepromatous leprosy.
Topics: Adolescent; Adult; Aged; Biopsy; Child; Clinical Trials as Topic; Dapsone; Drug Therapy, Combination | 1981 |
Effects of clofazimine alone or combined with dapsone on neutrophil and lymphocyte functions in normal individuals and patients with lepromatous leprosy.
Topics: Candida albicans; Cell Movement; Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Leprosy; L | 1982 |
Paucibacillary leprosy patients treated with multidrug therapy four years experience (1988 to 1991) in Bangladesh.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bangladesh; Child; Dapsone; Drug | 1994 |
An international randomized study with long-term follow-up of single versus combination chemotherapy of multibacillary leprosy.
Topics: Adolescent; Adult; Child; Dapsone; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Fo | 1994 |
Long-term evaluation of immune status in leprosy patients undergoing multiple drug therapy.
Topics: Agglutination Tests; Antibodies, Bacterial; Antigens, Bacterial; Clofazimine; Dapsone; Drug Therapy, | 1994 |
A randomized clinical trial of two single-dose treatments for paucibacillary leprosy.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Clofazimine; Dapsone; Drug Administration Schedule | 1994 |
Reversal reaction in multibacillary leprosy patients following MDT with and without immunotherapy with a candidate for an antileprosy vaccine, Mycobacterium w.
Topics: Bacterial Vaccines; Clofazimine; Combined Modality Therapy; Dapsone; Drug Therapy, Combination; Huma | 1993 |
Influence of acetylator phenotype on the haematological and biochemical effects associated with dapsone in leprosy patients.
Topics: Blood Cell Count; Blood Chemical Analysis; Clofazimine; Dapsone; Drug Therapy, Combination; Female; | 1997 |
Immunochemotherapy with interferon-gamma and multidrug therapy for multibacillary leprosy.
Topics: Adolescent; Adult; Antibodies, Bacterial; Child; Clofazimine; Dapsone; Drug Therapy, Combination; Fe | 1999 |
Effect of zafirlukast on leprosy reactions.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Clofazimine; Cohort Studies; D | 1999 |
Efficacy of WHO regimens in the management of leprosy patients with G6PD deficiency.
Topics: Adolescent; Adult; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Glucosephosphate Dehydro | 1999 |
Induction of lepromin positivity following immuno-chemotherapy with Mycobacterium w vaccine and multidrug therapy and its impact on bacteriological clearance in multibacillary leprosy: report on a hospital-based clinical trial with the candidate antilepro
Topics: Bacterial Vaccines; Clofazimine; Dapsone; Double-Blind Method; Drug Therapy, Combination; Humans; Im | 1999 |
Induction of lepromin positivity following immuno-chemotherapy with Mycobacterium w vaccine and multidrug therapy and its impact on bacteriological clearance in multibacillary leprosy: report on a hospital-based clinical trial with the candidate antilepro
Topics: Bacterial Vaccines; Clofazimine; Dapsone; Double-Blind Method; Drug Therapy, Combination; Humans; Im | 1999 |
Induction of lepromin positivity following immuno-chemotherapy with Mycobacterium w vaccine and multidrug therapy and its impact on bacteriological clearance in multibacillary leprosy: report on a hospital-based clinical trial with the candidate antilepro
Topics: Bacterial Vaccines; Clofazimine; Dapsone; Double-Blind Method; Drug Therapy, Combination; Humans; Im | 1999 |
Induction of lepromin positivity following immuno-chemotherapy with Mycobacterium w vaccine and multidrug therapy and its impact on bacteriological clearance in multibacillary leprosy: report on a hospital-based clinical trial with the candidate antilepro
Topics: Bacterial Vaccines; Clofazimine; Dapsone; Double-Blind Method; Drug Therapy, Combination; Humans; Im | 1999 |
Long-term follow up of multibacillary leprosy patients with high BI treated with WHO/MDT regimen for a fixed duration of two years.
Topics: Adult; Clofazimine; Cohort Studies; Dapsone; Drug Therapy, Combination; Female; Follow-Up Studies; H | 2000 |
Evidence for prevention of borderline leprosy reactions by dapsone.
Topics: Adolescent; Adult; Dapsone; Dose-Response Relationship, Drug; Female; Humans; Hypersensitivity, Dela | 1976 |
Borderline leprosy reactions and dapsone.
Topics: Clinical Trials as Topic; Dapsone; Dose-Response Relationship, Drug; Humans; Leprosy | 1977 |
Levamisole as adjunct to dapsone in leprosy.
Topics: Dapsone; Drug Synergism; Drug Therapy, Combination; Humans; Leprosy; Levamisole | 1976 |
The review of chemotherapeutric trials on leprosy and its present states in Korea.
Topics: Animals; Child; Clinical Trials as Topic; Dapsone; Haplorhini; Humans; Leprosy; Mycobacterium leprae | 1979 |
Clinical trial with rifampicin in the treatment of leprosy (final report).
Topics: Clinical Trials as Topic; Dapsone; Leprosy; Rifampin; Time Factors | 1977 |
Rifampicin for lepromatous leprosy: nine years' experience.
Topics: Animals; Clinical Trials as Topic; Dapsone; Drug Combinations; Humans; Leprosy; Mice; Mycobacterium | 1978 |
Long term effects of chemoprophylaxis among contacts of lepromatous cases. Results of 8 1/2 years follow-up.
Topics: Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Dapsone; Female; Follow-Up Studies; H | 1977 |
Management of household contacts of leprosy patients.
Topics: Adult; BCG Vaccine; Clinical Trials as Topic; Dapsone; Humans; Leprosy; Placebos; Risk | 1978 |
Extended studies on chemoprophylaxis against leprosy.
Topics: Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Dapsone; Double-Blind Method; Female; | 1978 |
Introductory rifampicin therapy in lepromatous leprosy: a six month follow-up study.
Topics: Clinical Trials as Topic; Dapsone; Double-Blind Method; Follow-Up Studies; Humans; Leprosy; Male; Ri | 1978 |
A statistical analysis of two chemotherapy trials in lepromatous leprosy. I. The response to therapy as measured by inoculation of mice.
Topics: Adolescent; Adult; Aged; Animals; Clinical Trials as Topic; Clofazimine; Dapsone; Female; Humans; Le | 1978 |
A statistical analysis of two chemotherapy trials in lepromatous leprosy. II. Interactions among patient variables.
Topics: Adolescent; Adult; Age Factors; Aged; Cell Count; Clinical Trials as Topic; Clofazimine; Dapsone; Fe | 1978 |
Evaluation of treatment of lepromatous leprosy patients in the Netherlands.
Topics: Clinical Trials as Topic; Clofazimine; Dapsone; Drug Evaluation; Humans; Leprostatic Agents; Leprosy | 1979 |
Therapeutic effects of adding rimactane (rifampicin) 450 milligrams daily or 1200 milligrams once monthly in a single dose to dapsone 50 milligrams daily in patients with lepromatous leprosy.
Topics: Adolescent; Adult; Aged; Child; Clinical Trials as Topic; Dapsone; Drug Therapy, Combination; Female | 1979 |
'Pulsed' rifampicin therapy in leprosy. A clinical study.
Topics: Adolescent; Adult; Clinical Trials as Topic; Dapsone; Humans; Leprosy; Nasal Septum; Rifampin; Skin; | 1979 |
Short course two months treatment of paucibacillary leprosy with rifampicin. Preliminary results.
Topics: Adolescent; Adult; Clinical Trials as Topic; Dapsone; Female; Humans; Leprosy; Male; Rifampin | 1979 |
Susceptibility of Mycobacterium leprae to dapsone as a determinant of patient response to acedapsone.
Topics: Acedapsone; Animals; Clinical Trials as Topic; Dapsone; Humans; Injections, Intramuscular; Leprosy; | 1976 |
Spaced clofazimine therapy of lepromatous leprosy.
Topics: Adolescent; Adult; Aged; Biopsy; Clofazimine; Dapsone; Drug Evaluation; Female; Humans; Leprosy; Mal | 1976 |
Clinical trial of DADDS in lepromatous leprosy.
Topics: Adolescent; Adult; Clinical Trials as Topic; Dapsone; Erythema Nodosum; Female; Humans; Injections, | 1976 |
Chemoprophylaxis among contacts of non-lepromatous leprosy.
Topics: Adolescent; Age Factors; Child; Child, Preschool; Clinical Trials as Topic; Dapsone; Female; Humans; | 1976 |
Clinical trial with rifampicin in the treatment of leprosy.
Topics: Adolescent; Adult; Clinical Trials as Topic; Dapsone; Female; Humans; Leprosy; Male; Middle Aged; Ri | 1976 |
Rifampin therapy of lepromatous leprosy.
Topics: Acetamides; Animals; Clinical Trials as Topic; Dapsone; Drug Administration Schedule; Erythema Nodos | 1975 |
Acedapsone (DADDS) treatment of leprosy patients in the Karimui of Papua New Guinea: status at six years.
Topics: Acetamides; Adolescent; Adult; Aged; Bacterial Infections; Child; Child, Preschool; Clinical Trials | 1975 |
Long-term follow-up of clofazimine (Lamprene) in the management of reactive phases of leprosy.
Topics: Clinical Trials as Topic; Clofazimine; Dapsone; Female; Follow-Up Studies; Humans; Leprosy; Pregnanc | 1975 |
A controlled clinical trial of continuous and intermittent rifampicin therapy during an initial three months period in lepromatous leprosy: final analysis.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Clofazimine; Dapsone; Female; Humans; Leprosy; Ma | 1975 |
Combined therapy in leprosy.
Topics: Adult; Clinical Trials as Topic; Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Leprostati | 1975 |
Treatment of leprosy with rifampicin and isoprodian (L73A).
Topics: Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Iso | 1975 |
Clinical and bacteriological effects of rifampicin in combination with L73A in leprosy: observation for six months.
Topics: Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; | 1975 |
Rifampicin and isoprodian in combination in the treatment of leprosy.
Topics: Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; | 1975 |
Preliminary experience with rifampicin and isoprodian (L73A)--combination in lepromatous leprosy.
Topics: Adolescent; Adult; Aged; Child; Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Therapy, | 1975 |
Preliminary experience with rifampicin and isoprodian in combination in leprosy treatment.
Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Dapsone; Drug Combinations; Dr | 1975 |
Report of combined therapy in leprosy with rifampicin and isoprodian conducted at the Bisidimo-center, Ethiopia.
Topics: Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Therapy, Combination; Ethiopia; Female; H | 1975 |
A preliminary report on a therapeutic trial with acedapsone in lepromatous leprosy.
Topics: Acedapsone; Adult; Clinical Trials as Topic; Dapsone; Humans; Leprosy; Male | 1975 |
Low dose dapsone therapy in lepromatous leprosy.
Topics: Animals; Bone Marrow; Clinical Trials as Topic; Dapsone; Humans; Leprosy; Mice; Mycobacterium leprae | 1975 |
A report on a controlled clinical trial with conventional and one third conventional dose of dapsone administered orally once a week in lepromatous patients.
Topics: Administration, Oral; Clinical Trials as Topic; Dapsone; Drug Administration Schedule; Humans; Lepro | 1975 |
Treatment of multibacillary leprosy with a regimen of 13 weeks duration.
Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Ethionamide; Humans; Leprostatic Agents; Leprosy; P | 1992 |
A controlled therapeutic trial in paucibacillary leprosy comparing a single dose of rifampicin with a single dose of rifampicin followed by one year of daily dapsone. The Collaborative Study Group for the Treatment of Leprosy in Zaire.
Topics: Dapsone; Democratic Republic of the Congo; Drug Administration Schedule; Drug Therapy, Combination; | 1991 |
Evaluation of five treatment regimens, using either dapsone monotherapy or several doses of rifampicin in the treatment of paucibacillary leprosy.
Topics: Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leprosy; Mycobacterium lep | 1990 |
Multidrug therapy for treatment of paucibacillary leprosy in western Kenya--preliminary communications.
Topics: Adolescent; Adult; Child; Child, Preschool; Dapsone; Drug Administration Schedule; Drug Therapy, Com | 1990 |
Relapse rate and incidence of dapsone resistance in lepromatous leprosy patients in Addis Ababa: risk factors and effect of short-term supplementary treatment.
Topics: Adolescent; Adult; Dapsone; Drug Combinations; Drug Resistance; Humans; Isoniazid; Leprosy; Recurren | 1985 |
Pyrazinamide as a part of combination therapy for BL and LL patients--a preliminary report.
Topics: Adolescent; Adult; Animals; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Isoniaz | 1988 |
Multi centre evaluation of "DDS tile test" for detection of dapsone in urine.
Topics: Dapsone; Humans; Leprosy; Multicenter Studies as Topic; Patient Compliance | 1989 |
Combined regimens of one year duration in the treatment of multibacillary leprosy--I. Combined regimens with rifampicin administered during one year.
Topics: Clinical Trials as Topic; Clofazimine; Cohort Studies; Dapsone; Drug Administration Schedule; Ethion | 1989 |
Combined regimens of one year duration in the treatment of multibacillary leprosy--II. Combined regimens with rifampicin administered during 6 months.
Topics: Clinical Trials as Topic; Clofazimine; Cohort Studies; Dapsone; Drug Administration Schedule; Ethion | 1989 |
[Diucifon and dimocifon in the combined therapy of leprosy (14-year observation)].
Topics: Clinical Trials as Topic; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Leprostatic | 1988 |
Primary dapsone resistance in Bamako and Chingleput: final report; THELEP. Subcommittee on Clinical Trials of the Chemotherapy of Leprosy (THELEP) Scientific Working Group of the UNDP/World Bank/WHO Special Programme for Research and Training in Tropical
Topics: Adult; Clinical Trials as Topic; Dapsone; Drug Resistance, Microbial; Humans; India; Leprosy; Mali; | 1987 |
A controlled therapeutic trial in paucibacillary leprosy comparing a single dose of rifampicin followed by 1 year of daily dapsone with 10 weekly doses of rifampicin.
Topics: Clinical Trials as Topic; Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Humans; | 1987 |
The THELEP controlled clinical drug trials. Subcommittee on Clinical Trials of the Chemotherapy of Leprosy (THELEP). Scientific Working Group of the UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases.
Topics: Adult; Clinical Trials as Topic; Dapsone; Drug Resistance, Microbial; Female; Humans; Leprostatic Ag | 1987 |
The number of Mycobacterium leprae in the pretreatment biopsy-specimen does not determine the rate of response of patients with lepromatous leprosy to chemotherapy with acedapsone.
Topics: Acedapsone; Animals; Clinical Trials as Topic; Dapsone; Drug Evaluation; Humans; Leprosy; Mice; Myco | 1986 |
Superiority of the neonatally thymectomized Lewis rat (NTLR) to monitor a clinical trial in lepromatous leprosy of the two regimens of rifampin and dapsone.
Topics: Animals; Dapsone; Drug Therapy, Combination; Humans; Immune Tolerance; Immunosuppression Therapy; Le | 1986 |
Efficacy of different regimens in multibacillary leprosy.
Topics: Clinical Trials as Topic; Clofazimine; Dapsone; Drug Administration Schedule; Drug Therapy, Combinat | 1986 |
Comparison of DDS with two combined chemotherapy regimens for multibacillary leprosy. Results after 3 years of treatment. A prospective randomized multicentre study.
Topics: Adult; Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Isoniazid; Isonicotini | 1986 |
The evaluation of present antileprosy compounds.
Topics: Animals; Anti-Bacterial Agents; Clinical Trials as Topic; Dapsone; Disease Models, Animal; Drug Resi | 1969 |
Treatment of moderately severe erythema nodosum leprosum with clofazimine--a controlled trial.
Topics: Acetaminophen; Adolescent; Adult; Aged; Benzenesulfonates; Clinical Trials as Topic; Dapsone; Erythe | 1971 |
Clofazimine in leprosy.
Topics: Clinical Trials as Topic; Dapsone; Humans; Leprosy; Phenazines | 1972 |
Recent trends in leprosy research.
Topics: Animals; Clinical Trials as Topic; Dapsone; Foot; Humans; Immunoglobulins; Leprosy; Lymph Nodes; Mic | 1972 |
Spot test for DDS (diamino diphenyl sulphone) in urine under field conditions.
Topics: Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Dapsone; False Negative Reactions; Fa | 1972 |
Further experience with the rapid bactericidal effect of rifampin on Mycobacterium leprae.
Topics: Animals; Biopsy; Clinical Trials as Topic; Dapsone; Dose-Response Relationship, Drug; Humans; Lepros | 1974 |
The relationship of dapsone (DDS) therapy to erythema nodosum leprosum. Is it direct or indirect?
Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Dapsone; Drug Resistance, Micr | 1974 |
The therapeutic effect of 4,4'-diacetyldiamino-diphenylsulfone (DADDS) in leprosy.
Topics: Adult; Biopsy; Body Weight; Clinical Trials as Topic; Dapsone; Erythema Nodosum; Female; Humans; Inj | 1968 |
Second trial of low dosages of DDS in lepromatous leprosy.
Topics: Clinical Trials as Topic; Dapsone; Humans; Leprosy | 1969 |
Experimental and clinical studies on rifampicin in treatment of leprosy.
Topics: Animals; Clinical Trials as Topic; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mice; Mycob | 1970 |
[Current state of thalidomide treatment of leprosy and leprosy reaction].
Topics: Clinical Trials as Topic; Dapsone; Drug Synergism; Female; Glucocorticoids; Humans; Leprosy; Male; P | 1970 |
The evaluation of present antileprosy compounds.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; BCG Vaccine; Clinical Trials as Topic; Dapson | 1969 |
Controlled clinical trial of clofazimine in untreated lepromatous leprosy.
Topics: Adult; Anti-Inflammatory Agents; Body Weight; Clinical Trials as Topic; Costs and Cost Analysis; Dap | 1971 |
Chemoprophylaxis in leprosy.
Topics: Adolescent; BCG Vaccine; Child; Child, Preschool; Clinical Trials as Topic; Dapsone; Female; Humans; | 1966 |
A clinical trial of sulforthomidine ('Fanasil' Roche) in lepromatous leprosy.
Topics: Clinical Trials as Topic; Dapsone; Humans; Leprosy; Malawi; Sulfonamides | 1966 |
898 other studies available for dapsone and Hansen Disease
| Article | Year |
|---|---|
Disease Burden and Current Therapeutical Status of Leprosy with Special Emphasis on Phytochemicals.
Topics: Cost of Illness; Dapsone; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy; Molecular | 2022 |
Interaction of constituents of MDT regimen for leprosy with Mycobacterium leprae HSP18: impact on its structure and function.
Topics: Antigens, Bacterial; Bacterial Proteins; Clofazimine; Dapsone; Heat-Shock Proteins; Host-Pathogen In | 2022 |
Asymptomatic low pulse oximetry measurements in leprosy patients in the time of COVID-19: Dapsone side effect.
Topics: COVID-19; Dapsone; Humans; Leprosy; Oximetry; SARS-CoV-2 | 2022 |
Antimicrobial Resistance among Leprosy Patients in Brazil: Real-World Data Based on the National Surveillance Plan.
Topics: Anti-Bacterial Agents; Brazil; Cross-Sectional Studies; Dapsone; Drug Resistance, Bacterial; Drug Th | 2022 |
Three doses of dapsone causing methemoglobinemia in leprosy: A report of two cases.
Topics: Dapsone; Humans; Leprostatic Agents; Leprosy; Methemoglobinemia | 2022 |
Implementation of genetic screening test to reduce the incidence of dapsone hypersensitivity syndrome among patients with leprosy in Papua, Indonesia: a study protocol.
Topics: Dapsone; Drug Hypersensitivity; Drug Therapy, Combination; Genetic Testing; Humans; Incidence; Indon | 2022 |
Ofloxacin resistance in multibacillary new leprosy cases from Purulia, West Bengal: a threat to effective secondary line treatment for rifampicin-resistant leprosy cases.
Topics: Animals; Dapsone; Drug Resistance, Bacterial; Leprostatic Agents; Leprosy; Mice; Mycobacterium lepra | 2022 |
Investigating drug resistance of Mycobacterium leprae in the Comoros: an observational deep-sequencing study.
Topics: Comoros; Dapsone; Drug Resistance, Bacterial; Drug Therapy, Combination; Humans; Leprostatic Agents; | 2022 |
A prospective case control study of resistance to rifampicin, dapsone and ofloxacin in Type 1 and Type 2 leprosy reactions and the therapeutic impact of modified treatment regimen on reactions.
Topics: Case-Control Studies; Dapsone; Drug Therapy, Combination; Humans; Hypersensitivity; Leprostatic Agen | 2023 |
[Suna no utsuwa (Castle of Sand): A Film Concerning Hansen's Disease].
Topics: Dapsone; Eye; Humans; Japan; Leprosy; Treatment Outcome | 2022 |
[Suna no utsuwa (Castle of Sand): A Film Concerning Hansen's Disease].
Topics: Dapsone; Eye; Humans; Japan; Leprosy; Treatment Outcome | 2022 |
[Suna no utsuwa (Castle of Sand): A Film Concerning Hansen's Disease].
Topics: Dapsone; Eye; Humans; Japan; Leprosy; Treatment Outcome | 2022 |
[Suna no utsuwa (Castle of Sand): A Film Concerning Hansen's Disease].
Topics: Dapsone; Eye; Humans; Japan; Leprosy; Treatment Outcome | 2022 |
Hi-plex deep amplicon sequencing for identification, high-resolution genotyping and multidrug resistance prediction of Mycobacterium leprae directly from patient biopsies by using Deeplex Myc-Lep.
Topics: Biopsy; Dapsone; Drug Resistance, Bacterial; Drug Resistance, Multiple; Genotype; Humans; Leprosy; M | 2023 |
High frequency of ofloxacin resistance patterns of Mycobacterium leprae from India: An indication to revisit second line anti-leprosy treatment regimen.
Topics: Cross-Sectional Studies; Dapsone; Drug Resistance, Bacterial; Drug Therapy, Combination; Humans; Ind | 2023 |
Assessment of Clinical, Histopathological, and Bacteriological Findings in Treated Leprosy Patients with Persistent Skin Lesions: A Retrospective Cohort Study.
Topics: Cohort Studies; Dapsone; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy; Male; Retro | 2023 |
HLA Screening for Dapsone Hypersensitivity in India-A Long Way Ahead.
Topics: Dapsone; HLA-B Antigens; Humans; India; Leprosy; Prospective Studies | 2019 |
HLA Screening for Dapsone Hypersensitivity in India-A Long Way Ahead-In Reply.
Topics: Dapsone; HLA-B Antigens; Humans; India; Leprosy; Prospective Studies | 2019 |
A double blow for a patient with leprosy: a reversal reaction and an adverse drug reaction.
Topics: Adrenal Cortex Hormones; Adult; Dapsone; Drug Eruptions; Humans; Leprostatic Agents; Leprosy; Male | 2019 |
Computer-aided synthesis of dapsone-phytochemical conjugates against dapsone-resistant Mycobacterium leprae.
Topics: Computer Simulation; Dapsone; Humans; Leprostatic Agents; Leprosy; Mycobacterium leprae; Phytochemic | 2020 |
A case of dapsone hypersensitivity syndrome in an Indian leprosy patient: Retrospective screening reveals the genetic connection with HLA-B*13:01.
Topics: Dapsone; HLA-B Antigens; Humans; Leprostatic Agents; Leprosy; Retrospective Studies | 2020 |
4,4'-Diaminodiphenyl Sulfone (DDS) as an Inflammasome Competitor.
Topics: Alzheimer Disease; Clofazimine; Cognitive Dysfunction; Coronavirus Infections; COVID-19; Dapsone; Hu | 2020 |
The Clinical Trend of Leprosy from 2000 to 2016 in Kaohsiung, a Major International Harbor City in Taiwan, Where Leprosy is Almost Eradicated.
Topics: Adult; Aged; Dapsone; Disease Eradication; Female; Humans; Leprosy; Leprosy, Lepromatous; Male; Midd | 2021 |
Validation study of HLA-B*13:01 as a biomarker of dapsone hypersensitivity syndrome in leprosy patients in Indonesia.
Topics: Adolescent; Adult; Alleles; Biomarkers; Case-Control Studies; Clofazimine; Dapsone; Drug Hypersensit | 2020 |
Dapsone-induced methaemoglobinaemia in leprosy: a close mimic of 'happy hypoxia' in the COVID-19 pandemic.
Topics: COVID-19; Dapsone; Humans; Hypoxia; Leprosy; Methemoglobinemia; Pandemics; SARS-CoV-2 | 2021 |
The influence of leprosy-related clinical and epidemiological variables in the occurrence and severity of COVID-19: A prospective real-world cohort study.
Topics: Adrenal Cortex Hormones; BCG Vaccine; Brazil; Clofazimine; Cohort Studies; COVID-19; COVID-19 Drug T | 2021 |
Severe type 1 upgrading leprosy reaction in a renal transplant recipient: a paradoxical manifestation associated with deficiency of antigen-specific regulatory T-cells?
Topics: Antigens, Bacterial; Dapsone; Drug Therapy, Combination; Graft Rejection; Humans; Immune Reconstitut | 2017 |
qPCR-High resolution melt analysis for drug susceptibility testing of Mycobacterium leprae directly from clinical specimens of leprosy patients.
Topics: Bacterial Proteins; Dapsone; DNA, Bacterial; Drug Resistance, Bacterial; Humans; Leprostatic Agents; | 2017 |
Painless Nodular Rash in a Young Man.
Topics: Adult; Clofazimine; Dapsone; Diagnosis, Differential; Exanthema; Humans; Leprostatic Agents; Leprosy | 2017 |
A docking model of dapsone bound to HLA-B*13:01 explains the risk of dapsone hypersensitivity syndrome.
Topics: Computational Biology; Dapsone; Drug Hypersensitivity Syndrome; HLA-B Antigens; Humans; Leprostatic | 2017 |
A case of leprosy in central Florida.
Topics: Aged; Biopsy; Dapsone; Diagnosis, Differential; Florida; Humans; Leprostatic Agents; Leprosy; Male; | 2017 |
Leprosy in Nonimmigrant Canadian Man without Travel outside North America, 2014.
Topics: Aged; Anti-Bacterial Agents; Canada; Dapsone; Drug Therapy, Combination; Florida; Humans; Leprostati | 2018 |
Multiple cranial nerve palsies secondary to a recurrence of Hansen's disease.
Topics: Adult; Cranial Nerve Diseases; Dapsone; Diagnosis, Differential; Drug Therapy, Combination; Humans; | 2018 |
The Function of HLA-B*13:01 Involved in the Pathomechanism of Dapsone-Induced Severe Cutaneous Adverse Reactions.
Topics: Adult; Aged, 80 and over; Alleles; Antigens, Differentiation, T-Lymphocyte; Coculture Techniques; Da | 2018 |
Antimicrobial resistance in leprosy: results of the first prospective open survey conducted by a WHO surveillance network for the period 2009-15.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Biopsy, Needle; Brazil; Colombia; Dapsone; DNA Gyrase; Dr | 2018 |
Dapsone: An Update.
Topics: Agranulocytosis; Dapsone; Drug Hypersensitivity Syndrome; Humans; Leprostatic Agents; Leprosy; Methe | 2016 |
A Traditional NSAID Aspirin along with Clofazimine in Erythema Nodosum Leprosum Reaction: Study of Six Cases.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clofazimine; Dapsone; Drug Therapy, Combina | 2016 |
Dapsone Resistance in Leprosy Patients Originally from American Samoa, United States, 2010-2012.
Topics: American Samoa; Biopsy; Clofazimine; Dapsone; Drug Administration Schedule; Drug Resistance, Bacteri | 2018 |
Atypical rash.
Topics: Adult; Dapsone; Exanthema; Female; Humans; Leprostatic Agents; Leprosy; Rifampin | 2019 |
Screening HLA to Prevent Severe Drug Reactions-A Devil's Advocate Perspective.
Topics: Dapsone; HLA-B Antigens; Humans; Leprosy; Plant Extracts; Prospective Studies | 2019 |
Evaluation of Prospective HLA-B*13:01 Screening to Prevent Dapsone Hypersensitivity Syndrome in Patients With Leprosy.
Topics: Adult; Alleles; China; Clofazimine; Cohort Studies; Dapsone; Drug Hypersensitivity Syndrome; Drug Th | 2019 |
pH-responsive chitosan based hydrogels affect the release of dapsone: Design, set-up, and physicochemical characterization.
Topics: Chemical Phenomena; Chitosan; Dapsone; Drug Carriers; Drug Liberation; Hydrogels; Hydrogen-Ion Conce | 2019 |
Delayed Diagnosis of Leprosy in a Micronesian Soldier - Case Report.
Topics: Dapsone; Delayed Diagnosis; Exanthema; Humans; Leprostatic Agents; Leprosy; Male; Micronesia; Milita | 2019 |
Association between HLA-B*1301 and dapsone-induced hypersensitivity reactions among leprosy patients in China.
Topics: Adult; China; Dapsone; Drug Hypersensitivity; Female; HLA-B Antigens; Humans; Leprostatic Agents; Le | 2013 |
Dapsone hypersensitivity syndrome among leprosy patients in China.
Topics: Adolescent; Adult; Aged; Child; China; Dapsone; Drug Hypersensitivity; Female; Humans; Incidence; Le | 2012 |
An under-recognized cause of polyarthritis: leprosy.
Topics: Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Clofazimine; Dapsone; Delayed Diagnosis; | 2013 |
Drug resistance in patients with leprosy in the United States.
Topics: Anti-Bacterial Agents; Dapsone; DNA, Bacterial; Drug Resistance, Bacterial; Genes, Bacterial; Humans | 2014 |
HLA-B*13:01 and the dapsone hypersensitivity syndrome.
Topics: Adult; Dapsone; Drug Hypersensitivity; Drug Therapy, Combination; Female; Genetic Predisposition to | 2013 |
Different roads, same destination.
Topics: Dapsone; Drug Hypersensitivity; Female; HLA-B Antigens; Humans; Leprostatic Agents; Leprosy; Male | 2014 |
Clinical oxidative stress during leprosy multidrug therapy: impact of dapsone oxidation.
Topics: Adult; Analysis of Variance; Catalase; Clofazimine; Cytochrome P-450 CYP2C19; Dapsone; Drug Therapy, | 2014 |
A short history of dapsone, or an alternative model of drug development.
Topics: Antimalarials; Antitubercular Agents; Dapsone; History, 20th Century; Humans; Leprostatic Agents; Le | 2011 |
Synthesis and evaluation of novel dapsone-thalidomide hybrids for the treatment of type 2 leprosy reactions.
Topics: Animals; Anti-Bacterial Agents; Cell Line; Dapsone; Dose-Response Relationship, Drug; Humans; Lepros | 2014 |
Leprosy in the South Pacific.
Topics: Communicable Disease Control; Dapsone; Female; Humans; Leprosy; Male | 2014 |
The leprosy problem in the South Pacific.
Topics: Adolescent; Adult; Child; Child, Preschool; Communicable Disease Control; Dapsone; Female; Humans; I | 2014 |
Leprosy.
Topics: Aged, 80 and over; Clofazimine; Dapsone; Humans; Leprostatic Agents; Leprosy; Male; Mycobacterium le | 2014 |
Computational Modelling of Dapsone Interaction With Dihydropteroate Synthase in Mycobacterium leprae; Insights Into Molecular Basis of Dapsone Resistance in Leprosy.
Topics: Dapsone; Dihydropteroate Synthase; Drug Resistance, Bacterial; Humans; Hydrogen Bonding; Leprosy; Mo | 2015 |
Drug resistance in Mycobacterium leprae from patients with leprosy in China.
Topics: Adult; Bacterial Proteins; China; Dapsone; DNA, Bacterial; Drug Resistance, Bacterial; Female; Human | 2015 |
An inflammatory myopathy unmasks a case of leprosy in an Italian patient.
Topics: Dapsone; Humans; Leprostatic Agents; Leprosy; Male; Middle Aged; Myositis; Rifampin; Treatment Outco | 2015 |
Incidence and patterns of hemolytic anemia in acute dapsone overdose.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anemia, Hemolytic; Dapsone; Drug Overdose; Humans; Incid | 2016 |
A lethal case of the dapsone hypersensitivity syndrome involving the myocardium.
Topics: Adult; Dapsone; Drug Hypersensitivity; Fatal Outcome; Female; Heart; Humans; Leprostatic Agents; Lep | 2016 |
Discovery of a potential lead compound for treating leprosy with dapsone resistance mutation in M. leprae folP1.
Topics: Amino Acid Sequence; Binding Sites; Dapsone; Dihydropteroate Synthase; Drug Discovery; Drug Resistan | 2016 |
Editorial Commentary: Drug-Resistance in Leprosy: Moving Toward Understanding the Scope of the Problem and How to Tackle It.
Topics: Dapsone; Drug Therapy, Combination; Humans; Leprosy; Mycobacterium leprae; Rifampin | 2016 |
Transmission of Drug-Resistant Leprosy in Guinea-Conakry Detected Using Molecular Epidemiological Approaches.
Topics: Antibiotics, Antitubercular; Antitubercular Agents; Biopsy; Dapsone; DNA, Bacterial; Drug Resistance | 2016 |
Leprosy Drug Resistance Surveillance in Colombia: The Experience of a Sentinel Country.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Proteins; Child; Colombia; Dapsone; DNA, Bacte | 2016 |
Leprosy in the UK.
Topics: Clofazimine; Dapsone; Humans; Leprostatic Agents; Leprosy; Peripheral Nervous System Diseases; Rifam | 2016 |
Hansen's disease in Portugal: multibacillary patients treated between 1988 and 2003.
Topics: Aged; Anti-Bacterial Agents; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Lepros | 2009 |
[Sensory-motor neuropathy: a slow and misleading case of leprosy].
Topics: Adrenal Cortex Hormones; Aged; Aspirin; Clofazimine; Dapsone; Diagnosis, Differential; Female; Human | 2008 |
A case of leprosy treated by the diazone.
Topics: Dapsone; Humans; Leprosy | 1948 |
New observations on the use of diasona in the treatment of leprosy.
Topics: Dapsone; Humans; Leprosy | 1948 |
Three cases of leprosy treated with diasone.
Topics: Dapsone; Humans; Leprosy | 1948 |
Can leprosy be eradicated with chemotherapy? An evaluation of the Malta Leprosy Eradication Project.
Topics: Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Isoniazid; Leprostatic Agents | 2008 |
A retrospective study of the effect of modified multi-drug therapy in Nepali leprosy patients following the development of adverse effects due to dapsone.
Topics: Adolescent; Adult; Aged; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Leprostati | 2008 |
Dapsone-induced haemolytic anaemia, hepatitis and agranulocytosis in a leprosy patient with normal glucose-6-phosphate-dehydrogenase activity.
Topics: Adult; Agranulocytosis; Anemia, Hemolytic; Chemical and Drug Induced Liver Injury; Dapsone; Glucosep | 2008 |
[Trends in therapy for Hansen disease].
Topics: Dapsone; Humans; Japan; Leprosy; Minocycline; Plant Oils; Quinolones; Rifampin | 2009 |
Acute Generalized Exanthematous Pustulosis (AGEP) due to dapsone in a patient with leprosy.
Topics: Acute Disease; Adult; Dapsone; Drug Eruptions; Humans; Leprostatic Agents; Leprosy; Male; Skin Disea | 2009 |
Twenty five years follow up of MB leprosy patients retreated with a modified MDT regimen after a full course of dapsone mono-therapy.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Dapsone; Drug Therapy, Combination; Female; Follow-U | 2009 |
Tattoos and paucibacillary leprosy.
Topics: Dapsone; Female; Humans; Leprostatic Agents; Leprosy; Middle Aged; Rifampin; Tattooing | 2009 |
Agranulocytosis induced by multidrug therapy in leprosy treatment: a case report.
Topics: Adult; Agranulocytosis; Anemia, Hemolytic; Clofazimine; Dapsone; Drug Therapy, Combination; Female; | 2009 |
Diasone in the treatment of leprosy.
Topics: Dapsone; Leprosy | 1946 |
Promin therapy.
Topics: Dapsone; Humans; Leprosy | 1946 |
The action of diasone in the treatment of leprosy; preliminary report.
Topics: Dapsone; Leprosy | 1946 |
Present status of promin treatment in leprosy.
Topics: Dapsone; Humans; Leprosy | 1946 |
Lest we forget Hansen's disease (leprosy): an unusual presentation with an acute onset of inflammatory polyarthritis and the rheumatology experience.
Topics: Acute Disease; Aged; Arthritis; Clofazimine; Dapsone; Diagnosis, Differential; Drug Therapy, Combina | 2009 |
Innovative use of dapsone.
Topics: Adult; Anti-Infective Agents; Autoimmune Diseases; Child; Dapsone; Humans; Hypersensitivity; Jaundic | 2010 |
Minocycline is effective and cosmetically preferred to clofazimine by leprosy patients in New York.
Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Hyperpigmentation; Leprostatic Agents; Lepr | 2010 |
Present status of diasone in the treatment of leprosy.
Topics: Dapsone; Leprosy | 1946 |
Regressive changes in leprosy under promin therapy.
Topics: Dapsone; Leprosy | 1946 |
Possible mode of emergence for drug-resistant leprosy is revealed by an analysis of samples from Mexico.
Topics: Bacterial Proteins; Dapsone; DNA Gyrase; DNA, Bacterial; Drug Resistance, Bacterial; Drug Therapy, C | 2010 |
Mutation analysis of the Mycobacterium leprae folP1 gene and dapsone resistance.
Topics: Bacterial Proteins; Dapsone; Dihydropteroate Synthase; DNA Mutational Analysis; Drug Resistance, Bac | 2011 |
Causes of death among active leprosy patients in China.
Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Cause of Death; China; Dapsone; Drug Hypers | 2011 |
Concurrent Hansen disease and pulmonary tuberculosis.
Topics: Adult; Antibiotics, Antitubercular; Comorbidity; Dapsone; Drug Therapy, Combination; Humans; Leprosy | 2011 |
Childhood leprosy: lest we forget.
Topics: Adolescent; Chemoprevention; Child; Child Welfare; Dapsone; Female; Humans; India; Leprostatic Agent | 2011 |
Adverse effects of multi-drug therapy in leprosy, a two years' experience (2006-2008) in tertiary health care centre in the tribal region of Chhattisgarh State (Bastar, Jagdalpur).
Topics: Adolescent; Adult; Body Mass Index; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; | 2011 |
Detection of mutations in folp1, rpoB and gyrA genes of M. leprae by PCR- direct sequencing--a rapid tool for screening drug resistance in leprosy.
Topics: Animals; Bacterial Proteins; Biopsy; Clofazimine; Cross-Sectional Studies; Dapsone; Dihydropteroate | 2011 |
Transmission of dapsone-resistant leprosy detected by molecular epidemiological approaches.
Topics: Bacterial Proteins; Dapsone; Humans; India; Leprostatic Agents; Leprosy; Molecular Epidemiology; Mut | 2011 |
Evaluation of multi-drug therapy for leprosy in the United States using daily rifampin.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Aged; Biopsy; Clofazimine; Dapsone; Drug Adm | 2011 |
Present situation of leprosy in Japan, 2006-2010: analysis of drug resistance in new registered and relapsed cases by molecular biological methods.
Topics: Adult; Aged; Dapsone; Drug Resistance, Bacterial; Female; Humans; Japan; Leprostatic Agents; Leprosy | 2012 |
The chemotherapy of leprosy: an interpretive history.
Topics: Dapsone; Female; History, 20th Century; History, 21st Century; Humans; Leprostatic Agents; Leprosy; | 2012 |
Developing new MDT regimens for MB patients; time to test ROM 12 month regimens globally.
Topics: Clofazimine; Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leprostatic A | 2012 |
Hemolytic anemia in patients receiving daily dapsone for the treatment of leprosy.
Topics: Adolescent; Adult; Aged; Anemia, Hemolytic; Brazil; Clofazimine; Dapsone; Drug Therapy, Combination; | 2012 |
Haematological alterations in leprosy patients treated with dapsone.
Topics: Adolescent; Adult; Antimalarials; Blood Cell Count; Case-Control Studies; Dapsone; Female; Hemoglobi | 2002 |
Drug susceptibility of Mycobacterium leprae: a retrospective analysis of mouse footpad inoculation results from 1983 to 1997.
Topics: Adult; Animals; Clofazimine; Dapsone; Drug Resistance, Multiple, Bacterial; Female; Humans; India; L | 2002 |
French dapsone survey.
Topics: Chemical and Drug Induced Liver Injury; Dapsone; Drug Hypersensitivity; France; Health Care Surveys; | 2002 |
The schizophrenic career of a "monster drug".
Topics: Dapsone; Erythema Nodosum; Humans; Leprostatic Agents; Leprosy; Leprosy, Lepromatous; Nervous System | 2003 |
Short report: Treatment failure in Hansen's disease.
Topics: Adolescent; Adult; Aged; Child; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Lep | 2003 |
Effectiveness of multidrug therapy in multibacillary leprosy: a long-term follow-up of 34 multibacillary leprosy patients treated with multidrug regimens till skin smear negativity.
Topics: Acedapsone; Adult; Clofazimine; Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Fe | 2003 |
What is the actual male/female sex ratio in leprosy patients?
Topics: Dapsone; Female; Humans; Leprostatic Agents; Leprosy; Male; Nigeria; Severity of Illness Index; Sex | 2003 |
Secondary rifampin resistance following multi-drug therapy--a case report.
Topics: Dapsone; Drug Resistance, Bacterial; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; L | 2003 |
Sulfoxone, diasone, sodium dermatitis; unusual distribution in a patient with leprosy.
Topics: Dapsone; Dermatitis; Drug Eruptions; Humans; Leprosy; Sodium; Sulfones | 1952 |
[III. Action of compounds structurally related to the 4,4'-diaminodiphenyl sulfone on the development of murine leprosy; sulfoxide, sulfide, benzophenone and amine].
Topics: Amines; Benzophenones; Dapsone; Leprosy; Safrole; Sulfides; Sulfones; Sulfoxides | 1952 |
[Chemotherapy of leprosy. II. Compounds structurally related to 4,4'-diaminodiphenylsulfone; chemical studies].
Topics: Dapsone; Leprosy; Sulfones | 1952 |
[Results of the treatment of 15 cases of lepromatous leprosy with 4-4'-diaminodiphenylsulfone].
Topics: Dapsone; Leprosy; Leprosy, Lepromatous; Sulfones | 1951 |
[Sulfone therapy of leprosy; fate of diaminodiphenylsulfone acetylsulfonamide administered orally; mode of action].
Topics: Dapsone; Leprosy; Sulfones | 1953 |
Diaminodiphenylsulphone in leprosy its oral and parenteral use; a comparison.
Topics: Dapsone; Leprosy; Sulfones | 1954 |
[Depot chemotherapy in the leprosy campaign in French West Africa; diaminodiphenylsulfone suspensions for bi-monthly injections].
Topics: Africa, Western; Dapsone; Ethnicity; Humans; Injections; Language; Leprosy; Sulfones; Suspensions | 1954 |
[Treatment of leprosy with diaminodiphenylsulfone].
Topics: Dapsone; Leprosy; Sulfones | 1954 |
[Treatment of leprosy with monthly injections of 2.50 g. of diaminodiphenylsulfone].
Topics: Dapsone; Injections; Leprosy; Sulfones | 1955 |
[Experiments with chlorpromazine combined with diaminodiphenyl sulfone in leprosy therapy].
Topics: Chlorpromazine; Dapsone; Leprosy; Sulfones | 1955 |
Experience with "avlosulfon" soluble.
Topics: Dapsone; Leprosy; Sulfones | 1956 |
Five years of mass dapsone (DDS) treatment.
Topics: Dapsone; Leprosy; Sulfones | 1956 |
[Three years of experience in therapy of leprosy with diaminodiphenylsulfone].
Topics: Dapsone; Leprosy; Sulfones | 1955 |
[Sulfonamidemia and diaminodiphenylsulfone; delay in large grains].
Topics: Dapsone; Edible Grain; Leprosy; Plant Structures; Sulfones | 1956 |
[Sulfonamidemia and diaminodiphenylsulfone; delay in large grains].
Topics: Dapsone; Edible Grain; Leprosy; Plant Structures; Sulfones | 1956 |
[Sulfonamidemia and diaminodiphenylsulfone; delay in large grains].
Topics: Dapsone; Edible Grain; Leprosy; Plant Structures; Sulfones | 1956 |
[Sulfonamidemia and diaminodiphenylsulfone; delay in large grains].
Topics: Dapsone; Edible Grain; Leprosy; Plant Structures; Sulfones | 1956 |
[Three years of treatment with diaminodiphenylsulfone in a rural environment].
Topics: Dapsone; Environment; Leprosy; Social Environment; Sulfones | 1957 |
[Promin in leprotic ulcers].
Topics: Dapsone; Humans; Leprosy; Sulfones; Ulcer | 1957 |
[Treatment of leprosy by sulfones, especially 4,4'-diaminodiphenylsulfone].
Topics: Dapsone; Leprosy; Sulfones | 1957 |
[Combination of red sarsaparilla & 4,4'-diaminodiphenylsulfone in therapy of lepromatous leprosy; study of 73 cases].
Topics: Biological Products; Dapsone; Leprosy; Leprosy, Lepromatous; Saponins; Smilax; Sulfones | 1957 |
[Radiological evolution of mutilations in lepers treated by diaminodiphenylsulfone].
Topics: Biological Evolution; Bone and Bones; Dapsone; Leprosy; Radiology; Sulfones | 1957 |
Treatment of plantar trophic ulcers with "novolep" in a rural leprosy centre.
Topics: Dapsone; Drug Combinations; Foot; Leprosy; Rural Population; Sulfones; Ulcer | 1960 |
[Concerning the eradication of leprosy? Influence of ambulatory treatment of leprosy, with DADPS, on the progression of leprous endemia and its results (1953-1959). Additional note on the relation existing between leprosy and allergy to tuberculin and the
Topics: Dapsone; Humans; Hypersensitivity; Immune System Diseases; Leprosy; Mycobacterium bovis; Sulfones; T | 1960 |
[Evaluation of the action of chemotherapy on Mycobacterium leprae in animals fed a prooxidant diet].
Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Dapsone; Diet; Fatty Acids; Leprosy; Mycobact | 1963 |
A clinical trial of etisul in lepromatous leprosy.
Topics: Dapsone; Humans; Leprosy; Leprosy, Lepromatous | 1963 |
DESENSITIZATION FOR DAPSONE DERMATITIS.
Topics: Dapsone; Dermatitis; Desensitization, Immunologic; Drug Eruptions; Leprosy; Sulfones; Toxicology | 1963 |
TREATMENT IN LEPROSY WITH ETISUL PRELIMINARY INFORMATION.
Topics: Antitubercular Agents; Benzoates; Dapsone; Humans; Leprosy | 1963 |
THE USE OF TRIAMCINOLONE IN THE TREATMENT OF SEVERE LEPRA REACTIONS.
Topics: Dapsone; Erythema Nodosum; Humans; Leprosy; Triamcinolone | 1963 |
KERATOACANTHOMA ASSOCIATED WITH LEPROSY.
Topics: Dapsone; Histological Techniques; Histology; Humans; India; Keratoacanthoma; Leprosy | 1963 |
DESENSITIZATION FOR DAPSONE DERMATITIS.
Topics: Dapsone; Dermatitis; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Leprosy; Sulfones; | 1963 |
CHEMOTHERAPEUTIC TRIALS IN LEPROSY. 1. COMPARATIVE TRIAL OF MACROCYCLON PLUS DAPSONE AND DAPSONE ALONE IN THE TREATMENT OF LEPROMATOUS LEPROSY.
Topics: Dapsone; Humans; Leprosy; Leprosy, Lepromatous; Polyethylene Glycols | 1963 |
SKELETAL LESIONS OF LEPROSY.
Topics: Bone Diseases; China; Dapsone; Humans; Leprosy; Osteoporosis; Radiography | 1963 |
LEPROMATOUS HANSEN'S DISEASE.
Topics: Communicable Disease Control; Dapsone; Humans; Leprosy; Leprosy, Lepromatous; Sulfones; Toxicology | 1964 |
MODERN TRENDS IN EPIDEMIOLOGY AND CONTROL OF LEPROSY.
Topics: Climate; Dapsone; Drug Therapy; Epidemiology; History; Humans; Leprosy; Public Health; Social Condit | 1964 |
POLYSENSITIVITY TO ANTI-LEPROSY DRUGS.
Topics: Dapsone; Drug Eruptions; Drug Hypersensitivity; Drug Resistance; Drug Resistance, Microbial; Humans; | 1964 |
[PRESENT STATE OF THE CHEMOTHERAPY OF LEPROSY].
Topics: Benzoates; Dapsone; Drug Therapy; Humans; Leprosy; Sulfanilamide; Sulfanilamides; Sulfonamides; Sulf | 1964 |
MYCOBACTERIAL DISEASE IN MAN AND ANIMALS. STUDIES ON LEPROSY BACILLI IN MAN AND ANIMALS.
Topics: Animals; Bacteriological Techniques; Dapsone; Drug Resistance; Drug Resistance, Microbial; Humans; L | 1964 |
FIXED ERUPTION IN DEEPLY PIGMENTED SUBJECTS: CLINICAL OBSERVATIONS ON 350 PATIENTS.
Topics: Black People; Congo; Dapsone; Diagnosis; Drug Eruptions; Drug Hypersensitivity; Exanthema; Leprosy; | 1964 |
[THE CHEMOTHERAPY OF LEPROSY].
Topics: Cycloserine; Dapsone; Drug Therapy; Humans; Isoniazid; Leprosy; Sulfamethoxypyridazine; Sulfones; Th | 1964 |
EFFECT OF CYCLOPHOSPHAMIDE ON LEPROSY. COMPETITIVE ACTION OF CYCLOPHOSPHAMIDE AND DAPSONE.
Topics: Antibody Formation; Cyclophosphamide; Dapsone; Immunochemistry; Leprosy; Leukocyte Count; Leukopenia | 1964 |
LEPROMATOUS HANSEN'S DISEASE IN A SUBURBAN COMMUNITY.
Topics: Dapsone; Diagnosis; Epidemiology; Humans; Leprosy; New Jersey; Pathology; Residence Characteristics; | 1965 |
A VARICELLIFORM ERUPTION APPEARING IN THE COURSE OF ACUTE EXACERBATION OF LEPROMATOUS LEPROSY.
Topics: Dapsone; Drug Therapy; Humans; Leprosy; Leprosy, Lepromatous; Microbiology; Skin Manifestations | 1965 |
LEPROSY. MYCOBACTERIAL NEURODERMATOSIS: REPORT OF A CASE.
Topics: Clinical Laboratory Techniques; Communicable Diseases; Dapsone; Drug Therapy; Female; Humans; Labora | 1965 |
CLINICAL ASPECTS OF LEPROSY.
Topics: Classification; Dapsone; Diagnosis; Drug Therapy; Epidemiology; Leprosy; Plant Oils; Sulfones | 1965 |
[LEPROSY IMPORTED INTO FRANCE].
Topics: Communicable Disease Control; Dapsone; Drug Therapy; Emigration and Immigration; Epidemiology; Franc | 1964 |
CONCENTRATION OF D. D. SULPHIDE AND D. D. SULPHONE IN VARIOUS BODY FLUIDS: A COMPARATIVE STUDY.
Topics: Body Fluids; Dapsone; Humans; Leprosy; Metabolism; Sulfides; Sulfones | 1963 |
LEPROSY CONTROL METHODS.
Topics: Dapsone; Drug Therapy; Humans; India; Leper Colonies; Leprosy; Outpatient Clinics, Hospital; Prevent | 1965 |
TOXIC EFFECTS OF PROLONGED HIGH-DOSE DAPSONE SELF-MEDICATION.
Topics: Dapsone; Humans; Leprosy; Self Medication; Toxicology; Uremia | 1965 |
[An intramuscular injection of 1.8 grams of diaminodiphenylsulfone may yield blood sulfones satisfactory for one month].
Topics: Dapsone; Injections, Intramuscular; Leprosy; Sulfones | 1954 |
Metabolism and excretion of di(p-aminophenyl) sulphoxide in different animal species.
Topics: Aniline Compounds; Animals; Biochemical Phenomena; Dapsone; Guinea Pigs; Leprosy; Oxidation-Reductio | 1960 |
[Two cases of Hansen's disease].
Topics: Aged; Dapsone; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy; Male; Recurrence; Rif | 2003 |
[Large scale production of 4,4-diaminodiphenylsulfone and derivatives for the antileprosy campaign in the State of São Paulo, Brazil].
Topics: Brazil; Dapsone; Leprosy; Sulfones | 1950 |
Diaminodiphenylsulphone in the treatment of leprosy.
Topics: Dapsone; Leprosy; Sulfones | 1951 |
Haemolytic anaemia during treatment of leprosy with diaminodiphenylsulphone by mouth.
Topics: Anemia; Anemia, Hemolytic; Dapsone; Humans; Leprosy; Mouth; Sulfones | 1951 |
[Note on some cases of leprosy (lepromatous type) treated with sulfones (diasone and sulfetrone)].
Topics: Dapsone; Humans; Leprosy; Sulfones | 1950 |
[Present status of experimentation with new leprosy therapy; thiosemicarbazones, oil suspensions of diaminodiphenylsulfone].
Topics: Dapsone; Empirical Research; Leprosy; Research Design; Sulfones; Suspensions; Thiosemicarbazones | 1950 |
[Results of diasone therapy in leprosy].
Topics: Dapsone; Humans; Leprosy; Sulfones | 1951 |
[Sulfone treatment of leprosy; fate of disubstituted sulfones in the body; mode of action].
Topics: Dapsone; Humans; Leprosy; Sulfones | 1951 |
[Antibacterial activity of streptomycin, p-aminosalicylic acid and diaminodiphenylsulfone on mice infected by Stefanski bacilli].
Topics: Aminosalicylic Acid; Animals; Anti-Bacterial Agents; Bacillus; Dapsone; Gram-Positive Bacteria; Inse | 1951 |
Toxic effects of diaminodiphenylsulphone in treatment of leprosy.
Topics: Dapsone; Leprosy; Sulfones | 1951 |
Diaminodiphenylsulphone (DDS) in leprosy: its effect on haemoglobin, weight, bacteriological index and reaction.
Topics: Body Weight; Body Weights and Measures; Dapsone; Hemoglobins; Leprosy; Sulfones | 1951 |
[Chemotherapy of leprosy. I. Effect of 4,4-diaminodiphenylsulfone in rat leprosy].
Topics: Animals; Dapsone; Leprosy; Peripheral Nervous System Diseases; Rats; Skin Diseases, Bacterial; Sulfo | 1951 |
[Use of diaminodiphenylsulfone in suspension in various vehicles in the treatment of leprosy].
Topics: Dapsone; Excipients; Leprosy; Sulfones; Suspensions | 1951 |
[Massive weekly oral administration of 4,4'-diaminodiphenylsulfone in the treatment of leprosy].
Topics: Administration, Oral; Dapsone; Leprosy; Sulfones | 1951 |
Treatment of leprosy with diaminodiphenyl sulphone (DDS).
Topics: Dapsone; Leprosy; Sulfones | 1952 |
Suspension of diaminodiphenylsulphone in leprosy.
Topics: Dapsone; Leprosy; Sulfones | 1952 |
Malaria, leprosy and dapsone.
Topics: Adolescent; Adult; Aged; Case-Control Studies; Dapsone; Female; Humans; Incidence; India; Leprostati | 2003 |
Shiny red-brown papules in a 21-year-old man. Histoid leprosy.
Topics: Adult; Clofazimine; Dapsone; Diagnosis, Differential; Drug Therapy, Combination; Face; Humans; Lepro | 2004 |
Active surveillance of leprosy contacts in country with low prevalence rate.
Topics: Adult; Antibodies, Bacterial; Antigens, Bacterial; Child; Dapsone; DNA-Directed RNA Polymerases; Dru | 2004 |
Should large lesions of leprosy be considered as "multibacillary" for treatment purposes even if the total number of lesions is less than five?
Topics: Dapsone; Humans; Leprostatic Agents; Leprosy; Mycobacterium leprae; Rifampin; World Health Organizat | 2004 |
Dapsone hypersensitivity or viral exanthem?
Topics: Dapsone; Diagnosis, Differential; Drug Hypersensitivity; Exanthema; Humans; Immunization; Leprostati | 2004 |
[Treatment of leprosy with succinyl-diaminodiphenyl-sulfone].
Topics: Dapsone; Leprosy; Sulfones | 1950 |
NEW and nonofficial remedies: sulfoxone sodium; diasone sodium.
Topics: Dapsone; Humans; Ions; Leprosy; Sodium; Sodium, Dietary | 1950 |
[Multi-drug resistant Mycobacterium leprae from patients with leprosy].
Topics: Animals; Base Sequence; Dapsone; DNA Gyrase; DNA-Directed RNA Polymerases; Drug Resistance, Multiple | 2004 |
DNA damage studies in untreated and treated leprosy patients.
Topics: Adolescent; Adult; Aged; Clofazimine; Dapsone; DNA Damage; Female; Humans; Leprostatic Agents; Lepro | 2004 |
Chemotherapy of leprosy.
Topics: Anti-Bacterial Agents; Clofazimine; Dapsone; Dose-Response Relationship, Drug; Drug Combinations; Dr | 2004 |
Dapsone syndrome with acute renal failure during leprosy treatment: case report.
Topics: Acute Kidney Injury; Adult; Clofazimine; Dapsone; Drug Hypersensitivity; Drug Therapy, Combination; | 2005 |
Trends of case detection and other indicators of leprosy in China during 1985-2002.
Topics: Adolescent; Adult; Age Factors; Child; China; Communicable Disease Control; Dapsone; Disability Eval | 2005 |
Remitting seronegative symmetrical synovitis with pitting edema in leprosy.
Topics: Aged; Clofazimine; Dapsone; Drug Therapy, Combination; Edema; Foot; Humans; Leprostatic Agents; Lepr | 2006 |
Renal hypersensitivity vasculitis associated with dapsone.
Topics: Adult; Anti-Bacterial Agents; Antitubercular Agents; Clofazimine; Cyclophosphamide; Dapsone; Drug Hy | 2005 |
[Leprosy situation in Myanmar before and after multidrug therapy].
Topics: Dapsone; Drug Therapy, Combination; Health Education; Humans; Leprostatic Agents; Leprosy; Myanmar; | 2005 |
[Dermopathy and peripheral neuropathy].
Topics: Aged; Clofazimine; Dapsone; Exanthema; Humans; Hypesthesia; Leprostatic Agents; Leprosy; Male; Rifam | 2005 |
Dihydropteroate synthase mutations in the folP1 gene predict dapsone resistance in relapsed cases of leprosy.
Topics: Animals; Dapsone; Dihydropteroate Synthase; Dose-Response Relationship, Drug; Drug Resistance, Bacte | 2006 |
Synthesis and antileprosy activity of some dialkyldithiocarbamates.
Topics: Animals; Colony Count, Microbial; Dapsone; Disease Models, Animal; Drug Therapy, Combination; Humans | 2006 |
Epidemiology of leprosy and response to treatment in Hong Kong.
Topics: Clofazimine; Dapsone; Drug Resistance, Bacterial; Drug Therapy, Combination; Hong Kong; Humans; Inci | 2006 |
Analysis of gene probes and gene amplification techniques for diagnosis and monitoring of treatment in childhood leprosy.
Topics: Adolescent; Child; Child Welfare; Dapsone; DNA Probes; DNA, Bacterial; Female; Humans; Leprostatic A | 2006 |
[Guideline for the treatment of Hansen's disease in Japan (Second edition)].
Topics: Clofazimine; Congenital Abnormalities; Dapsone; Drug Resistance, Microbial; Drug Therapy, Combinatio | 2006 |
Multidrug therapy regimen for leprosy.
Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy; Practice Guide | 2006 |
An unusual rash in an elderly man.
Topics: Age Factors; Aged, 80 and over; Clofazimine; Dapsone; Diagnosis, Differential; Exanthema; Humans; Le | 2007 |
NLEP--current situation and strategy during the 11th plan period (2007-2012).
Topics: Communicable Disease Control; Dapsone; Health Planning; Humans; India; Leprostatic Agents; Leprosy; | 2006 |
Multidrug therapy in leprosy.
Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy; Rifampin; Worl | 2006 |
Mortality due to dapsone hypersensitivity syndrome complicating multi-drug therapy for leprosy in Nepal.
Topics: Adolescent; Adult; Aged; Dapsone; Drug Hypersensitivity; Drug Therapy, Combination; Female; Humans; | 2007 |
Adverse effects from multi-drug therapy in leprosy: a Brazilian study.
Topics: Adult; Brazil; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Leprostatic Agents; | 2007 |
Morbus hansen, treated with promine.
Topics: Dapsone; Humans; Leprosy | 1948 |
Severe reaction resembling therapeutic shock in lepers following administration of diasone.
Topics: Dapsone; Leprosy; Shock | 1949 |
A case of leprosy treated with promin.
Topics: Dapsone; Humans; Leprosy | 1949 |
Modern treatment of leprosy; a report of ten cases on diasone treatment.
Topics: Dapsone; Humans; Leprosy | 1949 |
Injection of sulphetrone and diasone in leprosy.
Topics: Dapsone; Injections; Leprosy; Sulfones | 1949 |
Study of antileprosy activities of some dialkyldithiocarbamate derivatives.
Topics: Animals; Colony Count, Microbial; Dapsone; Drug Evaluation, Preclinical; Leprostatic Agents; Leprosy | 2007 |
Leprosy as immune reconstitution inflammatory syndrome in HIV-positive persons.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Dapsone; HIV Infections; Humans; Immu | 2007 |
[Study of rifampin and dapsone resistance in three patients with recurring leprosy].
Topics: Aged; Dapsone; DNA, Bacterial; Drug Resistance, Microbial; Humans; Leprostatic Agents; Leprosy; Male | 2008 |
Three indigenous cases of leprosy in the Mississippi delta.
Topics: Aged; Aged, 80 and over; Animals; Armadillos; Biopsy; Clofazimine; Dapsone; Diagnosis, Differential; | 2008 |
The role of the general practitioner in the diagnosis and treatment of leprosy.
Topics: Dapsone; Humans; India; Leprosy | 1967 |
Risk of infection in leprosy.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Dapsone; Female; Humans; Infant; Infant, Newborn; | 1967 |
The drug treatment of leprosy.
Topics: Dapsone; Humans; Leprosy; Sulfones; Thiourea | 1967 |
Dapsone and anti-dapsone antibody in circulating immune complexes in leprosy patients.
Topics: Antigen-Antibody Complex; Dapsone; Humans; Leprosy | 1980 |
Adverse reactions to dapsone.
Topics: Blood; Dapsone; Dermatitis Herpetiformis; Humans; Leprosy | 1981 |
Chemotherapy of leprosy.
Topics: Dapsone; Drug Therapy, Combination; Humans; Leprosy; World Health Organization | 1982 |
Intermittent chemotherapy of experimental leprosy in mice.
Topics: Animals; Dapsone; Drug Administration Schedule; Ethionamide; Female; Leprosy; Mice; Mycobacterium le | 1980 |
Combined treatment for lepromatous leprosy.
Topics: Acedapsone; Animals; Dapsone; Drug Therapy, Combination; Ethionamide; Humans; Leprostatic Agents; Le | 1980 |
Evaluation of multiple regimens in leprosy.
Topics: Clofazimine; Dapsone; Drug Evaluation; Drug Therapy, Combination; Humans; Leprosy; Male; Rifampin; S | 1981 |
Multiple drug therapy--a comparative study with 2 tier and 3 tier combination of rifampicin, clofazimine, DDS, INAH and thiacetazone in lepromatous cases.
Topics: Adolescent; Adult; Child; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Isoniazid | 1981 |
Leprosy in Vietnamese refugees: a case report.
Topics: Adult; Dapsone; Denmark; Female; Humans; Leprosy; Refugees; Vietnam | 1983 |
Evaluation of drug regimen in lepromatous leprosy--II.
Topics: Adult; Animals; Clofazimine; Dapsone; Drug Administration Schedule; Drug Resistance, Microbial; Huma | 1983 |
Side-effects of antileprosy drugs in common use.
Topics: Clofazimine; Dapsone; Drug Hypersensitivity; Ethionamide; Humans; Leprostatic Agents; Leprosy; Rifam | 1983 |
Leprosy in the Americas.
Topics: Americas; Dapsone; Drug Resistance; Drug Therapy, Combination; Humans; Leprosy; Research | 1984 |
Fixed genital drug eruption due to dapsone. A case report.
Topics: Adult; Dapsone; Drug Eruptions; Female; Genital Diseases, Female; Humans; Leprosy; Recurrence | 1982 |
[Survey on the prevalence rate of dapsone-resistant leprosy in the Yangzhou district].
Topics: Adult; Aged; China; Dapsone; Drug Resistance; Female; Humans; Leprosy; Male; Middle Aged | 1984 |
DDS 100 mg daily preventing permanent nerve damage in reversal reaction.
Topics: Dapsone; Humans; Leprosy; Peripheral Nervous System Diseases; Prednisolone | 1980 |
Intra-neural ceroid-like pigment following the treatment of lepromatous leprosy with clofazimine (B663; Lamprene).
Topics: Adult; Ceroid; Clofazimine; Dapsone; Drug Therapy, Combination; Histocytochemistry; Humans; Leprosy; | 1981 |
In vitro and in vivo effects of dapsone on neutrophil and lymphocyte functions in normal individuals and patients with lepromatous leprosy.
Topics: Cell Movement; Dapsone; Humans; Hydrogen Peroxide; In Vitro Techniques; Leprosy; Lymphocyte Activati | 1981 |
Rapid, radiolabeled-microculture method that uses macrophages for in vitro evaluation of Mycobacterium leprae viability and drug susceptibility.
Topics: Adult; Animals; Cells, Cultured; Dapsone; Female; Humans; In Vitro Techniques; Leprosy; Macrophages; | 1983 |
[Antibacterial treatment of bacteria-abundant leprosy].
Topics: Dapsone; Drug Therapy, Combination; History, 20th Century; Humans; Leprostatic Agents; Leprosy | 1983 |
Studies on sulphone resistant strains of M. leprae in field and institutionalized cases of leprosy.
Topics: Animals; Dapsone; Drug Resistance, Microbial; Humans; Institutionalization; Leprosy; Mice; Mycobacte | 1983 |
Dapsone-resistant leprosy.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Microbial Sensitivity Tests; Mycobacterium lep | 1983 |
Prevalence survey of secondary dapsone resistance in leprosy in Kancheepuram and Tiruvannamalai control units of Tamil Nadu.
Topics: Animals; Dapsone; Drug Resistance, Microbial; Humans; India; Leprosy; Mice; Mycobacterium leprae | 1983 |
Primary resistance to dapsone among untreated lepromatous patients in Bamako and Chingleput.
Topics: Animals; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Male; Mice; Mycobacterium leprae | 1983 |
Studies on dapsone-resistant Mycobacterium leprae in leprosy patients of Gudiyatham Taluk, the leprosy control area of the Schieffelin Leprosy Research and Training Centre, Karigiri. 2. A progress report.
Topics: Animals; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mice; Mycobacterium leprae | 1983 |
Dapsone-resistant leprosy in Jakarta: a preliminary report.
Topics: Animals; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mice; Mice, Inbred CBA; Mycobacterium | 1983 |
Secondary dapsone-resistant leprosy in Shanghai Municipality.
Topics: Animals; Dapsone; Drug Resistance, Microbial; Female; Humans; Leprosy; Male; Mice; Mycobacterium lep | 1983 |
Dapsone-resistant leprosy in Burundi.
Topics: Animals; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mice; Mycobacterium leprae | 1983 |
The treatment of leprosy.
Topics: Adult; Animals; Clofazimine; Dapsone; Drug Resistance, Microbial; Erythema Nodosum; Ethionamide; Hum | 1983 |
Relation between anti-Mycobacterium leprae antibody activity and clinical features in borderline tuberculoid (BT) leprosy.
Topics: Antibodies, Bacterial; Dapsone; Drug Resistance; Humans; Immunoglobulin G; Leprosy; Mycobacterium le | 1983 |
Effect of treatment on antibody activity against Mycobacterium leprae antigen 7 in tuberculoid leprosy.
Topics: Antibodies, Bacterial; Antibody Formation; Antigens, Bacterial; Dapsone; Drug Resistance; Humans; Le | 1983 |
How much non-infectious are the "non-infectious" lepromatous leprosy patients?
Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Leprosy; Mycobacterium leprae; Nose; Rifamp | 1983 |
Leprosy today.
Topics: Clofazimine; Dapsone; Disease Models, Animal; Drug Resistance, Microbial; Humans; Leprosy; Mycobacte | 1983 |
Suppression of the antibody response to sulfolipids in leprosy patients by 4,4'-diaminodiphenyl sulfone (DDS).
Topics: Antibodies; Antibody Formation; Dapsone; Humans; Leprosy; Lipids; Mycobacterium leprae | 1983 |
Adenosine triphosphate content of Mycobacterium leprae from leprosy patients.
Topics: Adenosine Triphosphate; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mycobacterium leprae | 1984 |
Multiple axonal myelination in the experimental mouse leprosy model.
Topics: Animals; Axons; Dapsone; Disease Models, Animal; Female; Leprosy; Mice; Mycobacterium leprae; Nerve | 1984 |
Dapsone-resistant leprosy.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mycobacterium leprae | 1984 |
Prevalence of secondary dapsone-resistant leprosy in Upper Volta.
Topics: Animals; Burkina Faso; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mice; Mycobacterium lep | 1984 |
Primary dapsone-resistant leprosy in San Francisco.
Topics: Adolescent; Adult; Aged; California; Dapsone; Diet; Drug Resistance, Microbial; Female; Humans; Lepr | 1984 |
Six cases of dapsone-resistant tuberculoid leprosy.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mycobacterium leprae; Tuberculosis | 1984 |
Lepromatous leprosy of the larynx.
Topics: Aged; Dapsone; Humans; Laryngeal Diseases; Leprosy; Male; Rifampin | 1983 |
[Secondary dapsone resistance in leprotic patients of the Shanghai district].
Topics: Animals; China; Dapsone; Drug Resistance, Microbial; Female; Humans; Leprosy; Male; Mice; Recurrence | 1983 |
Successful plasma exchange in type 1 leprosy reversal reaction.
Topics: Adult; Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Leprosy; Leukocyte Count; Male; Plas | 1984 |
Sulphone induced exfoliative dermatitis and hepatitis.
Topics: Adrenal Cortex Hormones; Adult; Chemical and Drug Induced Liver Injury; Dapsone; Dermatitis, Exfolia | 1980 |
[Histoid leprosy: clinical and experimental observations (author's transl)].
Topics: Adult; Dapsone; Drug Resistance, Microbial; Female; Humans; Leprosy; Male; Middle Aged | 1981 |
Specific health problems of Southeast Asian refugees in middle Tennessee.
Topics: Asia, Southeastern; Dapsone; Drug Therapy, Combination; Female; Hematologic Diseases; Hemoglobin E; | 1984 |
[Dimorphous leprosy].
Topics: Adult; Austria; Biopsy; Dapsone; Diagnosis, Differential; Female; Humans; Leprosy; Male; Middle Aged | 1984 |
Childhood leprosy and social response in south India.
Topics: Adolescent; Adult; Child; Child, Preschool; Community Health Services; Dapsone; Female; Health Educa | 1984 |
Vitamin E and dapsone-induced hemolysis.
Topics: Adult; Aged; Dapsone; Dermatitis Herpetiformis; Erythrocyte Count; Female; Heinz Bodies; Hemoglobins | 1984 |
Late reversal reaction after combined treatment of a patient with multibacillary leprosy.
Topics: Dapsone; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy; Male; Middle Aged; Prothion | 1984 |
Incidence of anemia in leprosy patients treated with dapsone.
Topics: Adolescent; Adult; Aged; Anemia; Dapsone; Female; Humans; Leprosy; Male; Middle Aged | 1984 |
Hypersensitivity reaction to dapsone: report from Malaysia.
Topics: Adolescent; Dapsone; Dermatitis Herpetiformis; Drug Hypersensitivity; Female; Humans; Leprosy; Malay | 1984 |
Treatment of leprosy in rural India as seen on a medical student elective.
Topics: Clofazimine; Dapsone; Developing Countries; Drug Therapy, Combination; Humans; India; Leprosy; Patie | 1984 |
NADH-methemoglobin reductase and methemoglobinemia among leprosy patients.
Topics: Adult; Cytochrome-B(5) Reductase; Dapsone; Female; Humans; Leprosy; Male; Methemoglobinemia; NADH, N | 1984 |
A study of blood ascorbic acid in leprosy.
Topics: Ascorbic Acid; Dapsone; Erythema Nodosum; Humans; Leprosy; Skin Ulcer; Socioeconomic Factors | 1984 |
Sural nerve biopsy in leprosy patients after varying periods of treatment: histopathological and bacteriological findings on light microscopy.
Topics: Adolescent; Adult; Biopsy; Child; Dapsone; Female; Humans; Leprostatic Agents; Leprosy; Male; Middle | 1984 |
Comparative study of two regimens of combined chemotherapy of one year duration in multibacillary leprosy. Results after four and five years' follow-up.
Topics: Adolescent; Adult; Dapsone; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Isonicotin | 1984 |
Oral zinc as an adjunct to dapsone in lepromatous leprosy.
Topics: Adult; Dapsone; Erythema Nodosum; Female; Humans; Leprosy; Male; Middle Aged; Zinc | 1984 |
Rationale of the multidrug regimens recommended by a World Health Organization Study Group on Chemotherapy of Leprosy for Control Programs.
Topics: Dapsone; Drug Resistance; Humans; Leprostatic Agents; Leprosy | 1984 |
Cancer mortality among patients with Hansen's disease.
Topics: Asian; Black or African American; Dapsone; Female; Hispanic or Latino; Humans; Leprosy; Lymphoma; Ma | 1984 |
Effect of dapsone (DDS) on T-cells and their response to PHA and lepromin in tuberculoid leprosy patients.
Topics: B-Lymphocytes; Dapsone; Female; Humans; Lepromin; Leprosy; Leukocyte Count; Lymphocyte Activation; M | 1983 |
Paper spot test and DDS/creatinine ratios in relation to treatment taken by leprosy patients.
Topics: Creatinine; Dapsone; Humans; Leprosy; Monitoring, Physiologic | 1983 |
Precipitation of type-I (upgrading) reaction in leprosy by skin testing with antigen and irritants.
Topics: Adult; Dapsone; Dinitrochlorobenzene; Humans; Irritants; Lepromin; Leprosy; Male; Neuritis; Nitroben | 1983 |
Utilization of medical agencies and treatment compliance by urban (Madras) leprosy patients.
Topics: Adolescent; Adult; Child; Dapsone; Female; Humans; India; Leprosy; Male; Patient Acceptance of Healt | 1983 |
Leprosy in five armadillo handlers.
Topics: Adolescent; Adult; Aged; Animals; Armadillos; Dapsone; Disease Reservoirs; Humans; Leprosy; Male; Mi | 1983 |
New approaches to chemotherapy for leprosy.
Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy; Rifampin | 1983 |
Field application of combined therapy for infectious leprosy cases. A feasibility study in Bombay.
Topics: Adolescent; Adult; Clofazimine; Dapsone; Drug Evaluation; Drug Therapy, Combination; Humans; India; | 1983 |
Operational study to monitor the regularity of dapsone intake by leprosy out-patients.
Topics: Adolescent; Adult; Child; Dapsone; Female; Humans; India; Leprosy; Male; Patient Compliance; Self Ad | 1983 |
Oral zinc in recurrent Erythema Nodosum Leprosum reaction.
Topics: Administration, Oral; Adult; Clofazimine; Dapsone; Drug Therapy, Combination; Erythema Nodosum; Fema | 1983 |
Application of "tile reaction" test for screening dapsone in urine.
Topics: Dapsone; Humans; Leprosy; Patient Compliance; Self Administration | 1983 |
Tile test to monitor the self administration of dapsone by leprosy patients.
Topics: Dapsone; Humans; Leprosy; Methods; Patient Compliance; Plastics; Self Administration | 1983 |
The effect of clofazimine on liver function tests in lepra reaction (ENL).
Topics: Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Blood Proteins; | 1983 |
An investigation of dapsone compliance using an isoniazid-marked formulation.
Topics: Adolescent; Adult; Aged; Capsules; Creatinine; Dapsone; Drug Combinations; Female; Humans; Isoniazid | 1983 |
Dapsone levels after oral therapy and weekly oily injections in Ethiopian leprosy patients.
Topics: Administration, Oral; Adult; Aged; Dapsone; Female; Humans; Leprosy; Male; Methemoglobin; Middle Age | 1983 |
Co-incident (simultaneous) dapsone sensitivity and dapsone-resistant leprosy.
Topics: Dapsone; Drug Resistance; Humans; Leprosy | 1983 |
Sex differences in the absorption of dapsone after intramuscular injection.
Topics: Absorption; Adolescent; Adult; Dapsone; Female; Humans; Injections, Intramuscular; Leprosy; Male; Mi | 1983 |
DDS-resistant infection among leprosy patients in the population of Gudiyatham Taluk, South India. Part 3. Prevalence, incidence, risk factors, and interpretation of mouse foot pad test results.
Topics: Dapsone; Drug Resistance, Microbial; Humans; India; Leprosy | 1983 |
The significance of dapsone (DDS)-resistant Mycobacterium leprae in untreated patients.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Leprosy | 1983 |
Response to dapsone (DDS) monotherapy in leprosy patients of Gudiyatham Taluk, South India: comparison between the 1960s and the 1970s.
Topics: Dapsone; Humans; Leprosy; Time Factors | 1983 |
Follow-up of lepromatous (LL and BL) patients on dapsone (DDS) monotherapy after attainment of smear negativity in Gudiyatham Taluk, South India.
Topics: Dapsone; Follow-Up Studies; Humans; Leprosy | 1983 |
Results of long-term domiciliary dapsone (DDS) monotherapy for lepromatous leprosy in Gudiyatham Taluk, South India.
Topics: Dapsone; Home Care Services; Humans; India; Leprosy; Time Factors | 1983 |
Simultaneous Type I and Type II reactions.
Topics: Dapsone; Female; Humans; Leprosy; Male | 1983 |
Hepatitis in leprosy patients treated by a daily combination of dapsone, rifampin, and a thioamide.
Topics: Adolescent; Adult; Aging; Amides; Chemical and Drug Induced Liver Injury; Dapsone; Drug Therapy, Com | 1983 |
Chemotherapy of leprosy; "bubble" or "calendar" packs for the administration of rifampin, dapsone, clofazimine, or prothionamide/ethionamide.
Topics: Clofazimine; Dapsone; Drug Packaging; Ethionamide; Humans; Leprostatic Agents; Leprosy; Prothionamid | 1983 |
[Lagophthalmos and posterior synechiae of the iris during treatment of leprosy with diaminodiphenylsulfone].
Topics: Adult; Dapsone; Drug Resistance, Microbial; Eyelid Diseases; Female; Humans; Iris Diseases; Leprosy; | 1984 |
Urine test to monitor dapsone self-administration in leprosy.
Topics: Dapsone; Humans; Leprosy; Self Administration | 1984 |
Norethisterone and ethinyl estradiol kinetics during dapsone therapy.
Topics: Adult; Contraceptives, Oral, Combined; Dapsone; Drug Interactions; Ethinyl Estradiol; Female; Humans | 1984 |
Short-course multi-drug therapy for paucibacillary patients in Guyana: preliminary communication.
Topics: Dapsone; Drug Therapy, Combination; Humans; Leprosy; Rifampin | 1984 |
Dapsone-resistant leprosy in Addis Ababa: a progress report.
Topics: Dapsone; Drug Resistance, Microbial; Ethiopia; Humans; Leprosy | 1984 |
Co-incident (simultaneous) dapsone sensitive and dapsone resistant leprosy.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mycobacterium leprae | 1982 |
Leprosy and its chemotherapy.
Topics: Clofazimine; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mycobacterium leprae; Rifampin | 1982 |
Serum macrophage migration inhibition activity in patients with leprosy.
Topics: Dapsone; Dinitrochlorobenzene; Humans; Hypersensitivity, Delayed; Leprosy; Macrophage Migration-Inhi | 1982 |
Class specific anti-Mycobacterium leprae antibody assay in lepromatous leprosy (BL-LL) patients during the first two to four years of DDS treatment.
Topics: Antibodies, Anti-Idiotypic; Antibody Formation; Antigens, Bacterial; Dapsone; Humans; Immunoglobulin | 1982 |
Malaria incidence in leprosy patients under dapsone therapy in Karbi-Anglong district, Assam.
Topics: Adult; Antimalarials; Child; Dapsone; Humans; India; Leprosy; Malaria; Plasmodium falciparum | 1982 |
In vitro lymphocyte stimulation in patients with lepromatous and borderline tuberculoid leprosy. The effect of dapsone treatment on the response to Mycobacterium leprae antigens, tuberculin purified protein derivative and non-mycobacterial stimulants.
Topics: Adolescent; Adult; Aged; Antigens, Bacterial; Concanavalin A; Dapsone; Female; Humans; Immunity, Cel | 1982 |
The six disease of WHO.
Topics: Adult; Animals; Dapsone; Drug Administration Schedule; Drug Resistance, Microbial; Humans; Leprosy; | 1981 |
Increase in prevalence of leprosy caused by dapsone-resistant Mycobacterium leprae.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mycobacterium leprae | 1982 |
Detection of externally induced impairments in single bacterial cells by laser microbe mass analysis.
Topics: Animals; Bacteria; Dapsone; Escherichia coli; Lasers; Leprosy; Mass Spectrometry; Mice; Mycobacteriu | 1982 |
Chemotherapy of leprosy for control programmes.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Leprostatic Agents; Leprosy; Mycobacterium leprae | 1982 |
Further results on dapsone-resistant leprosy in Bamako (Mali).
Topics: Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mali | 1983 |
[Change in ophthalmological findings in Hansen's disease during chemotherapy].
Topics: Adult; Dapsone; Eye Diseases; Humans; Leprosy | 1983 |
Social and personality factors in dapsone resistant patients.
Topics: Adult; Dapsone; Drug Resistance, Microbial; Female; Humans; Leprosy; Male; Middle Aged; Patient Comp | 1983 |
Dapsone compliance in an urban field project.
Topics: Dapsone; Humans; India; Leprosy; Patient Compliance; Urban Population | 1983 |
Concentration of serum calcium in leprosy.
Topics: Calcium; Dapsone; Humans; Leprosy | 1983 |
Chemotherapy of leprosy for control programmes: scientific basis and practical application.
Topics: Clofazimine; Costs and Cost Analysis; Dapsone; Drug Resistance, Microbial; Humans; Leprostatic Agent | 1983 |
A study of case-holding in leprosy patients in Asia, based on duration of treatment, 1976-80.
Topics: Ambulatory Care; Asia; Dapsone; Female; Humans; Leprosy; Male; Time Factors | 1983 |
A study of 922 bacteriologically positive leprosy cases.
Topics: Adolescent; Adult; Child; Child, Preschool; Dapsone; Female; Humans; Infant; Leprosy; Male; Middle A | 1982 |
Effect of dapsone on blood lactic and pyruvic acids in leprosy.
Topics: Dapsone; Humans; Lactates; Leprosy; Pyruvates | 1982 |
Primary dapsone-resistant leprosy in Republic of Korea.
Topics: Dapsone; Drug Resistance; Humans; Leprosy | 1982 |
Leprosy in Auckland.
Topics: Adult; Clofazimine; Dapsone; Female; Fiji; Humans; Independent State of Samoa; Leprosy; Male; New Ze | 1980 |
The treatment of leprosy in Papua New Guinea.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Leprostatic Agents; Leprosy; Papua New Guinea | 1982 |
Phytohaemagglutinin (PHA)-induced transformation of peripheral blood-lymphocytes in leprosy patients.
Topics: Dapsone; Humans; Leprosy; Lymphocyte Activation; Phytohemagglutinins; T-Lymphocytes | 1980 |
The epidemiological situation of leprosy in India.
Topics: Cross-Sectional Studies; Dapsone; Drug Resistance, Microbial; Humans; India; Leprosy; Urban Health | 1981 |
The epidemiological situation in Africa.
Topics: Africa; Cross-Sectional Studies; Dapsone; Drug Resistance, Microbial; Female; Humans; Leprosy; Male | 1981 |
Illness and service utilization behaviours of leprosy patients.
Topics: Cross-Sectional Studies; Dapsone; Female; Health Services; Humans; India; Leprosy; Male; Medicine, T | 1982 |
Mechansism of action of DDS.
Topics: Dapsone; Escherichia coli; Folic Acid Antagonists; Leprosy; Mycobacterium leprae | 1980 |
Combined rifampin and dapsone chemotherapy of Mycobacterium leprae infection of the neonatally thymectomized Lewis rat.
Topics: Animals; Dapsone; Drug Therapy, Combination; Female; Leprosy; Male; Mice; Mice, Inbred BALB C; Model | 1980 |
Secondary sulphone resistance in leprosy (Report of a case).
Topics: Adult; Animals; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Male; Mice; Mycobacterium lepr | 1980 |
Dapsone-resistant leprosy in a population of Bamako (Mali).
Topics: Animals; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mali; Mice; Mycobacterium leprae | 1980 |
ELISA inhibition technique for the demonstration of sulphones in body fluids. II. A new method to monitor leprosy patient compliance under field conditions.
Topics: Dapsone; Enzyme-Linked Immunosorbent Assay; Humans; Immunoenzyme Techniques; Leprosy; Methods; Patie | 1981 |
Combined chemotherapy against Mycobacterium leprae in the mouse.
Topics: Animals; Dapsone; Drug Therapy, Combination; Leprosy; Mice; Mycobacterium leprae; Prothionamide; Str | 1980 |
ELISA inhibition technique for the demonstration of sulphones in body fluids. The use of dried blood on filter paper to monitor leprosy patient compliance.
Topics: Body Fluids; Dapsone; Enzyme-Linked Immunosorbent Assay; Humans; Immunoenzyme Techniques; Leprosy; P | 1981 |
The association of pregnancy and leprosy. II. Pregnancy in dapsone-resistant leprosy.
Topics: Dapsone; Drug Resistance, Microbial; Ethiopia; Female; Humans; Leprosy; Mycobacterium leprae; Pregna | 1981 |
Activity of the combination of isoniazid, protionamide and dapsone against Mycobacterium leprae and some other mycobacteria.
Topics: Animals; Dapsone; Drug Interactions; Drug Therapy, Combination; Isoniazid; Isonicotinic Acids; Lepro | 1981 |
Thymus-dependent lymphocytes in leprosy. II. Effect of chemotherapy on T-lymphocyte subpopulations.
Topics: Antibodies, Monoclonal; Dapsone; Erythema Nodosum; Humans; Leprosy; Lymphocyte Activation; Mycobacte | 1982 |
The problem of dapsone-resistant leprosy.
Topics: Animals; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mice; Mycobacterium leprae | 1981 |
Primary dapsone-resistant leprosy in Cebu, Philippines.
Topics: Animals; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mice; Mice, Inbred CBA; Mycobacterium | 1981 |
Dapsone-resistant leprosy-the THELEP approach.
Topics: Animals; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mice; Mycobacterium leprae | 1981 |
Bacterial growth kinetics of "M. lufu" in the presence and absence of various drugs alone and in combination. A model for the development of combined chemotherapy against M. leprae?
Topics: Animals; Antitubercular Agents; Dapsone; Drug Therapy, Combination; Humans; Kinetics; Leprostatic Ag | 1982 |
Renal transplantation in leprosy.
Topics: Adult; Dapsone; Humans; Immunosuppression Therapy; Kidney Failure, Chronic; Kidney Transplantation; | 1982 |
The clinical diagnosis of dapsone resistant leprosy.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mycobacterium leprae; Skin | 1982 |
Intramuscular injection of dapsone in therapy for leprosy: a new approach.
Topics: Adult; Dapsone; Female; Humans; Injections, Intramuscular; Leprosy; Male; Middle Aged; Time Factors | 1982 |
Follow-up on short-course 2 months' rifampicin treatment of paucibacillary leprosy.
Topics: Dapsone; Follow-Up Studies; Humans; Leprosy; Rifampin | 1982 |
Possible incompatibility of dapsone with clofazimine in the treatment of patients with erythema nodosum leprosum.
Topics: Clofazimine; Dapsone; Erythema Nodosum; Female; Humans; Leprosy; Male | 1982 |
Histoid lepromas.
Topics: Dapsone; Drug Resistance, Microbial; Female; Histiocytes; Humans; Leprosy; Middle Aged; Skin; Time F | 1982 |
PHA induced blastoid transformation of lymphocytes in leprosy contacts.
Topics: Dapsone; Humans; Leprosy; Lymphocyte Activation; Phytohemagglutinins | 1982 |
Level of serum sodium in leprosy.
Topics: Dapsone; Humans; Leprosy; Sodium; Tuberculosis | 1982 |
Skin of leprosy patients before and after treatment: electron microscopic study.
Topics: Dapsone; Humans; Leprosy; Macrophages; Microscopy, Electron; Rifampin; Skin | 1982 |
Monitoring the regularity of self administration of dapsone by leprosy patients.
Topics: Adolescent; Adult; Aged; Child; Dapsone; Female; Humans; Leprostatic Agents; Leprosy; Male; Middle A | 1982 |
Unusual reaction to intramuscular sulfone in two leprosy patients in Malaysia.
Topics: Adult; Dapsone; Female; Humans; Injections, Intramuscular; Leprosy; Malaysia; Male; Middle Aged; Mus | 1980 |
Leprosy treatment and control of leprosy in India. (Assessment of achievements and suggestions for the future).
Topics: Community Health Services; Dapsone; Humans; India; Leprosy; Oils; Plant Oils | 1980 |
Prevalence of secondary dapsone resistance in Gudiyattam Taluk, the leprosy control area of the Schieffelin Leprosy Research and Training Centre, Karigiri. 1. Preliminary report.
Topics: Dapsone; Drug Resistance; Humans; India; Leprosy | 1980 |
[Leprosy in Bulgaria. Epidemiology, Clinical forms and treatment (author's transl)].
Topics: Adult; Aged; Bulgaria; Dapsone; Female; Humans; Leprosy; Male; Middle Aged; Phenylthiourea | 1981 |
Dapsone induced hypohaptoglobinemia in lepromatous leprosy patients.
Topics: Adult; Alkaline Phosphatase; Dapsone; Haptoglobins; Hemoglobins; Hemolysis; Humans; L-Lactate Dehydr | 1981 |
A quantitative assay of porphyrins in leprosy patients. A spectrophotometric study.
Topics: Coproporphyrins; Dapsone; Humans; Leprosy; Porphyrins; Protoporphyrins; Spectrophotometry; Uroporphy | 1981 |
Some thoughts on the present status and future prospects of chemotherapy of leprosy based on experience with treating tuberculosis.
Topics: Dapsone; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Leprosy; Rifampin; Tuberculo | 1981 |
Rifampin 1200 mg once monthly together with daily Lamprene and dapsone in treatment of refactory patients with lepromatous leprosy.
Topics: Adolescent; Adult; Clofazimine; Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Fe | 1981 |
DDS 100 mg daily, the cornerstone in the management of reversal reaction.
Topics: Dapsone; Humans; Leprosy; Peripheral Nerves; Prednisone | 1981 |
The nose in lepromatous leprosy; bacteriological and histopathological studies of patients treated with dapsone monotherapy for varying periods of time.
Topics: Dapsone; Humans; Leprosy; Nasal Mucosa; Nose; Time Factors | 1982 |
Effect of single dose (1500 mg) rifampicin on infectivity of patients with lepromatous leprosy.
Topics: Animals; Dapsone; Follow-Up Studies; Humans; Leprosy; Mice; Rifampin | 1980 |
Is dapsone safe?
Topics: Anemia, Hemolytic; Dapsone; Glucosephosphate Dehydrogenase Deficiency; Humans; Leprosy | 1981 |
Drug interactions -- the influence of rifampicin and clofazimine on the urinary excretion of DDS.
Topics: Clofazimine; Creatinine; Dapsone; Drug Interactions; Humans; Leprosy; Rifampin | 1981 |
Quantitative DNCB epicutaneous sensitization in leprosy patients and controls.
Topics: Dapsone; Dinitrochlorobenzene; Humans; Immunity, Cellular; Leprosy; Nitrobenzenes; Skin Tests; Tuber | 1981 |
Dapsone haemolysis in leprosy. A preliminary report.
Topics: Adolescent; Adult; Aged; Anemia, Hemolytic; Bilirubin; Child; Dapsone; Female; Hemolysis; Humans; Le | 1981 |
Leprosy in the Americas region (AMRO).
Topics: Adolescent; Child; Child, Preschool; Dapsone; Humans; Infant; Infant, Newborn; Leprosy; Mexico; Pan | 1980 |
Fatal reaction to dapsone during treatment of leprosy.
Topics: Adolescent; Dapsone; Erythema; Humans; Leprosy; Male; Skin; Thalidomide | 1981 |
The problem of dapsone-resistant leprosy: diagnosis and management.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Leprosy | 1981 |
Dapsone compliance in North-east India.
Topics: Dapsone; Humans; India; Leprosy; Male; Patient Compliance; Self Administration | 1981 |
An assessment of dapsone self-administration in Gudiyatham Taluk. How should urinary dapsone/creatinine ratios be used?
Topics: Creatinine; Dapsone; Humans; India; Leprosy; Patient Compliance; Self Administration | 1981 |
Clofazimine (lamprene or B663) in lepra reactions.
Topics: Adult; Clofazimine; Dapsone; Female; Humans; Leprosy; Prednisolone | 1981 |
Treatment of leprosy and immunologic considerations.
Topics: Adolescent; Adult; Child; Dapsone; Humans; India; Leprosy; Male | 1981 |
A study of cell mediated immunity in leprosy.
Topics: Adolescent; Adult; Child; Clofazimine; Dapsone; Female; Humans; Immunity, Cellular; Leprostatic Agen | 1981 |
Persister M. leprae after introductory rifampicin followed by dapsone therapy.
Topics: Animals; Dapsone; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Leprosy; Mice; Rifa | 1981 |
Deformities in leprosy patients of Indian armed forces treated/reviewed at Military Hospital Agra (a retrospective study).
Topics: Adolescent; Adult; Dapsone; Humans; India; Leprosy; Male; Middle Aged; Military Medicine; Retrospect | 1981 |
The self-administration of dapsone by leprosy patients in Ethiopia.
Topics: Dapsone; Ethiopia; Humans; Leprosy; Patient Compliance; Self Administration | 1981 |
Serum inhibitory factor in lepromatous leprosy: its effect on the pre-S-phase cell-cycle kinetics of mitogen-stimulated normal human lymphocytes.
Topics: Adult; Cell Count; Cell Cycle; Cells, Cultured; Concanavalin A; Dapsone; Humans; Leprosy; Lymphocyte | 1981 |
A study of hypo-pigmented lesions in children.
Topics: Child; Child, Preschool; Dapsone; Female; Humans; Leprosy; Male; Peripheral Nerves; Pigmentation Dis | 1981 |
Dapsone poisoning (a case report).
Topics: Adolescent; Athetosis; Cyanosis; Dapsone; Humans; Leprosy; Male; Methemoglobinemia | 1981 |
Leprosy in children and its impact on community health.
Topics: Adolescent; BCG Vaccine; Child; Child, Preschool; Dapsone; Humans; India; Infant; Infant, Newborn; L | 1981 |
[Bacilloscopic involution in dimorphous Virchowians treated with sulfones - Comparison with Virchowian patients treated with identical dosage].
Topics: Dapsone; Humans; Leprosy | 1981 |
Leprosy in a Vietnamese adoptee.
Topics: Child; Colorado; Dapsone; Female; Humans; Leprosy; Vietnam | 1980 |
Electrophysiological evidence for motor unit impairment during the treatment of leprosy.
Topics: Dapsone; Humans; Leprosy; Motor Endplate; Neural Conduction; Neuromuscular Junction; Peroneal Nerve; | 1980 |
Influence of sulphone therapy on lepromin reaction.
Topics: Acedapsone; Adult; Dapsone; Humans; Lepromin; Leprosy | 1980 |
Effect of DDS therapy on blood pyruvate and lactate levels in leprosy patients.
Topics: Dapsone; Humans; Lactates; Leprosy; Pyruvates | 1980 |
Study on drug interactions.
Topics: Adult; Clofazimine; Dapsone; Drug Interactions; Drug Therapy, Combination; Humans; Isoniazid; Lepros | 1980 |
Assessment of self administration of dapsone in urine by out-patients attending field clinics.
Topics: Dapsone; Humans; Leprosy; Outpatients; Patient Compliance; Self Administration | 1980 |
Clofazimine and dapsone--a combination therapy in erythema nodosum leprosum syndrome.
Topics: Adolescent; Adult; Clofazimine; Dapsone; Drug Therapy, Combination; Erythema Nodosum; Female; Humans | 1980 |
Erythema multiforme bullosum due to dapsone.
Topics: Adult; Dapsone; Erythema Multiforme; Female; Humans; Leprosy; Male | 1980 |
Serum lysozyme in leprosy.
Topics: Adolescent; Adult; Aged; Dapsone; Erythema Nodosum; Female; Humans; Leprosy; Male; Middle Aged; Mura | 1980 |
Thirty years of leprosy control work--what next?
Topics: Child; Child, Preschool; Dapsone; Education, Medical; Humans; India; Infant; Leprosy; Patient Compli | 1980 |
[Reconsidering the treatment of leprosy].
Topics: Animals; Dapsone; Drug Resistance; Humans; Leprosy; Mice; Rifampin | 1980 |
Relapse with multibacillary leprosy caused by rifampicin sensitive organisms following paucibacillary multidrug therapy.
Topics: Adult; Dapsone; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; Leprostatic A | 1995 |
Dapsone syndrome.
Topics: Adult; Chemical and Drug Induced Liver Injury; Dapsone; Diagnosis, Differential; Drug Hypersensitivi | 1995 |
Relapse rates in patients treated with dapsone monotherapy and combinations of dapsone and thiambutosine, thiacetazone, isoniazid and streptomycin in the pre-MDT era.
Topics: Dapsone; Drug Therapy, Combination; Female; Humans; Isoniazid; Leprostatic Agents; Leprosy; Male; Ph | 1994 |
[Long-term effect of leprosy control in both highly endemic prefectures, Weifang of Shandong and Wenshan of Yunnan].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; China; Dapsone; Drug Therapy, Combination; Female | 1995 |
Activity of combinations of dapsone, rifampin, minocycline, clarithromycin, and sparfloxacin against M. leprae-infected mice.
Topics: Animals; Anti-Infective Agents; Clarithromycin; Dapsone; Drug Therapy, Combination; Female; Fluoroqu | 1995 |
[The frequency of the appearance of perforating foot ulcers in patients with Hansen's disease as a function of treatment with disulone alone or with polychemotherapy].
Topics: Chronic Disease; Dapsone; Drug Therapy, Combination; Follow-Up Studies; Foot Ulcer; Humans; Leprosta | 1995 |
Prevention and early detection of leprosy in children.
Topics: Adolescent; Age Distribution; Child; Child, Preschool; Dapsone; Female; Fluorescent Antibody Techniq | 1995 |
Leprosy.
Topics: Clofazimine; Dapsone; Drug Administration Schedule; Drug Resistance, Microbial; Humans; Leprostatic | 1995 |
Application of polymerase chain reaction for the detection of Mycobacterium leprae DNA in specimens from treated leprosy patients.
Topics: Adult; Aged; Aged, 80 and over; Dapsone; DNA Primers; DNA, Bacterial; Female; Humans; Leprosy; Male; | 1995 |
Inhibition of the multiplication of Mycobacterium leprae in nude mice by intermittent administration of a new rifamycin derivative, 3'-hydroxy-5'-(4-isobutyl-1-piperazinyl)benzoxazinorifamycin (KRM-1648) combined with sparfloxacin.
Topics: Administration, Oral; Animals; Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Fem | 1995 |
A fatal case of drug-induced multi-organ damage in a patient with Hansen's disease: dapsone syndrome or rifampicin toxicity?
Topics: Acute Kidney Injury; Aged; Chemical and Drug Induced Liver Injury; Dapsone; Diagnosis, Differential; | 1995 |
Determination of dapsone in serum and saliva using reversed-phase high-performance liquid chromatography with ultraviolet or electrochemical detection.
Topics: Chromatography, High Pressure Liquid; Dapsone; Electrochemistry; Humans; Leprosy; Malaria, Falciparu | 1994 |
Treating Hansen's disease in developing countries.
Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Leprosy; Rifampin | 1994 |
Rate of relapse in multibacillary patients after cessation of long-course dapsone monotherapy supplemented by a final supervised single dose of 1500 mg of rifampin.
Topics: Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; | 1994 |
Useful plants of dermatology. I. Hydnocarpus and chaulmoogra.
Topics: Asia, Southeastern; Dapsone; Dermatology; Fatty Acids; History, 18th Century; History, Ancient; Huma | 1994 |
Effect of drug treatment on electroneurological measures of peripheral nerve function in leprosy patients.
Topics: Adolescent; Adult; Aged; Child; Clofazimine; Dapsone; Drug Therapy, Combination; Electrophysiology; | 1993 |
Therapeutic efficacy of benzoxazinorifamycin, KRM-1648, in combination with other antimicrobials against Mycobacterium leprae infection induced in nude mice.
Topics: Animals; Clofazimine; Dapsone; Drug Therapy, Combination; Leprostatic Agents; Leprosy; Mice; Mice, I | 1994 |
Side-effects of Isoprodian compared with WHO-MDT in rural Nepal.
Topics: Adolescent; Adult; Aged; Child; Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Human | 1993 |
Acetylation phenotype and genotype in aboriginal leprosy patients from the north-west region of Western Australia.
Topics: Acetylation; Adolescent; Adult; Aged; Aged, 80 and over; Arylamine N-Acetyltransferase; Australia; D | 1993 |
Therapeutic monitoring and pharmacist intervention in a Hansen's disease clinic.
Topics: Academic Medical Centers; Chicago; Clofazimine; Dapsone; Drug Monitoring; Humans; Leprosy; Patient C | 1993 |
Problems of leprosy relapse in China.
Topics: China; Clofazimine; Dapsone; Drug Therapy, Combination; Follow-Up Studies; Humans; Leprosy; Recurren | 1993 |
Fixed duration MDT in paucibacillary leprosy (classical and modified).
Topics: Dapsone; Drug Therapy, Combination; Follow-Up Studies; Humans; Leprostatic Agents; Leprosy; Recurren | 1993 |
Clarithromycin is bactericidal against strains of Mycobacterium leprae resistant and susceptible to dapsone and rifampin.
Topics: Administration, Oral; Animals; Clarithromycin; Dapsone; Drug Interactions; Drug Resistance, Microbia | 1993 |
Survey for secondary dapsone and rifampicin resistance in Cuba.
Topics: Animals; Dapsone; Drug Resistance, Microbial; Female; Humans; Leprosy; Male; Mice; Mice, Inbred BALB | 1993 |
Efficacy and safety of multidrug therapy in paucibacillary leprosy in Singapore.
Topics: Adult; Aged; Aged, 80 and over; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Lep | 1993 |
Reply: treatment of smear negative MB patients who had received previous dapsone monotherapy.
Topics: Dapsone; Humans; Leprosy | 1993 |
Acute dapsone poisoning.
Topics: Acute Disease; Adult; Dapsone; Humans; Leprosy; Male; Methemoglobinemia; Suicide, Attempted; Sulfhem | 1993 |
Effectiveness of a dapsone compliance program in leprosy.
Topics: Adult; Dapsone; Female; Humans; Leprosy; Male; Patient Compliance | 1993 |
Immunohistochemistry in histoid leprosy.
Topics: Aged; Antigens, CD1; CD36 Antigens; CD4-CD8 Ratio; Dapsone; Dendritic Cells; Drug Resistance; ErbB R | 1995 |
Urinary excretion of renal brush border membrane enzymes in leprosy patients--effect of multidrug therapy.
Topics: Alkaline Phosphatase; Biomarkers; Clofazimine; Dapsone; Drug Monitoring; Drug Therapy, Combination; | 1996 |
Drug resistance in Nepali leprosy patients.
Topics: Adolescent; Adult; Aged; Animals; Dapsone; Drug Resistance; Female; Humans; Leprosy; Male; Mice; Mid | 1996 |
Primary systemic amyloidoses: possible new directions in prophylaxis and therapy.
Topics: Alzheimer Disease; Amyloidosis; Anti-Inflammatory Agents, Non-Steroidal; Dapsone; Dementia; Humans; | 1996 |
Primary dapsone resistance in Cebu, The Philippines; cause for concern.
Topics: Animals; Dapsone; Drug Resistance, Microbial; Humans; Leprostatic Agents; Leprosy; Mice; Mice, Inbre | 1996 |
[The training of health personnel by the Marchoux Institute in Bamako from 1979 to 1995].
Topics: Academies and Institutes; Africa; Comprehensive Health Care; Dapsone; Delivery of Health Care, Integ | 1996 |
Dormancy, drug resistance or dependency; some thoughts to ponder.
Topics: Animals; Dapsone; Drug Resistance, Microbial; Humans; Leprostatic Agents; Leprosy; Mice; Mycobacteri | 1996 |
Antileprosy drugs, pregnancy and fetal outcome.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Animals; Clofazimine; Dapsone; Drug Therapy, Combina | 1996 |
Urinary tract carcinoma in leprosy patients treated with dapsone for a long period.
Topics: Aged; Aged, 80 and over; Analgesics; Dapsone; Female; Humans; Leprostatic Agents; Leprosy; Male; Mid | 1997 |
[Suspected leprosy].
Topics: Adult; Aged; Aged, 80 and over; Dapsone; Diagnosis, Differential; Female; Humans; Leprostatic Agents | 1997 |
Life after multidrug therapy: the managerial implications in leprosy control in Kaduna State, Nigeria.
Topics: Child; Dapsone; Disease Outbreaks; Drug Therapy, Combination; Health Education; Health Knowledge, At | 1997 |
Haematological and biochemical alterations in leprosy patients already treated with dapsone and MDT.
Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Leprostatic Agents; Leprosy; Male; | 1997 |
Studies on therapeutic activity of benzoxazinorifamycin KRM-1648 in combination with other antimicrobial agents and biological response modifiers interferon-gamma and granulocyte-macrophage colony-stimulating factor against M. leprae infection in athymic
Topics: Adoptive Transfer; Animals; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Granulocyte-Mac | 1997 |
[New WHO recommendations for the treatment of leprosy].
Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy; Minocycline; M | 1997 |
[Vitamin E as protective agent against hemolysis in leprosy patients under dapsone treatment].
Topics: Adult; Dapsone; Female; Hemolysis; Humans; Leprostatic Agents; Leprosy; Male; Middle Aged; Vitamin E | 1997 |
Leprosy.
Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy; Rifampin | 1997 |
Why multidrug therapy for multibacillary leprosy can be shortened to 12 months.
Topics: Clofazimine; Dapsone; Drug Administration Schedule; Drug Resistance, Microbial; Drug Therapy, Combin | 1998 |
Another view of the therapy of leprosy.
Topics: Animals; Anti-Bacterial Agents; Dapsone; Drug Therapy, Combination; Humans; Leprostatic Agents; Lepr | 1998 |
Serum markers of treatment success in leprosy.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers; Child; Clofazimine; Dapsone; Dr | 1999 |
Dapsone syndrome: hepatitis-B infection a risk factor for its development?
Topics: Adult; Amyloidosis; Dapsone; Female; Hepatitis B; Humans; Hypersensitivity; Leprosy; Lichenoid Erupt | 1999 |
Diaminodiphenylsulfone resistance of Mycobacterium leprae due to mutations in the dihydropteroate synthase gene.
Topics: Dapsone; Dihydropteroate Synthase; Drug Resistance, Microbial; Folic Acid Antagonists; Genes, Bacter | 1999 |
SIMLEP: a simulation model for leprosy transmission and control.
Topics: BCG Vaccine; Computer Simulation; Dapsone; Drug Therapy, Combination; Humans; Incidence; Leprostatic | 1999 |
Nasal mucosa and skin of smear-positive leprosy patients after 24 months of fixed duration MDT: histopathological and microbiological study.
Topics: Adult; Animals; Biological Assay; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Histocyto | 1999 |
The US-Japan Joint Leprosy Research Program meeting, San Francisco, June 28-30, 1999.
Topics: Anti-Infective Agents; Dapsone; Drug Resistance, Microbial; Fluoroquinolones; Humans; International | 1999 |
Studies on risk of leprosy relapses in China: relapses after treatment with dapsone monotherapy.
Topics: China; Dapsone; Follow-Up Studies; Humans; Leprostatic Agents; Leprosy; National Health Programs; Po | 1999 |
Trials of preventive therapy.
Topics: Acedapsone; Chemoprevention; Clinical Trials as Topic; Dapsone; Humans; India; Leprostatic Agents; L | 1999 |
Ominous sign of a disfiguring disease. Leprosy (Hansen's disease).
Topics: Adult; Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy; Leprosy | 2000 |
Clofazimine: new products. Major antileprous drug.
Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy; Rifampin; Trea | 1999 |
Effect of treatment on PCR positivity in multibacillary leprosy patients treated with conventional and newer drugs ofloxacin and minocycline.
Topics: Adenosine Triphosphate; Biopsy; Clofazimine; Dapsone; DNA, Bacterial; Drug Evaluation; Drug Therapy, | 1999 |
Leprosy: a close mimic in a rheumatology clinic.
Topics: Adult; Biopsy; Dapsone; Diagnosis, Differential; Female; Humans; Leprosy; Male; Middle Aged; Prednis | 1999 |
Dapsone resistance in Mycobacterium leprae.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Leprostatic Agents; Leprosy; Microbial Sensitivity Test | 2000 |
Care after cure in leprosy.
Topics: Aftercare; Dapsone; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy; Rifampin | 2001 |
Leprosy at a turning point?
Topics: Dapsone; Drug Resistance, Microbial; Drug Therapy, Combination; Ethiopia; Humans; Incidence; India; | 2000 |
Dapsone drug resistance in the MDT era.
Topics: Clofazimine; Dapsone; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Leprostatic Age | 2000 |
Hansen's disease in a native-born, United States resident, after a brief stay in an endemic area abroad.
Topics: Aged; Cell Count; China; Clofazimine; Dapsone; Diabetes Mellitus, Type 1; Emigration and Immigration | 2001 |
A Mycobacterium leprae isolate resistant to dapsone, rifampin, ofloxacin and sparfloxacin.
Topics: Animals; Anti-Infective Agents; Antitubercular Agents; Clarithromycin; Clofazimine; Colony Count, Mi | 2000 |
Increase in the incidence of dapsone hypersensitivity syndrome--an appraisal.
Topics: Adolescent; Adult; Dapsone; Drug Hypersensitivity; Female; Humans; Incidence; India; Leprostatic Age | 2001 |
Simultaneous detection of Mycobacterium leprae and its susceptibility to dapsone using DNA heteroduplex analysis.
Topics: Base Sequence; Dapsone; DNA, Bacterial; Drug Resistance, Microbial; Heteroduplex Analysis; Humans; L | 2001 |
The prevalence of folP1 mutations associated with clinical resistance to dapsone, in Mycobacterium leprae isolates from South Korea.
Topics: Adult; Aged; Animals; Dapsone; Dihydropteroate Synthase; Drug Resistance, Microbial; Female; Humans; | 2001 |
Peroxidase in therapy of experimentally induced leprosy.
Topics: Administration, Oral; Animals; Dapsone; Dose-Response Relationship, Drug; Erythrocyte Count; Hemoglo | 2001 |
Does dapsone resistance really matter in the MDT era?
Topics: Dapsone; Drug Resistance, Microbial; Humans; Leprostatic Agents; Leprosy; Mycobacterium leprae | 2001 |
[Comparative characterization of the antigenic composition of M. leprae and M. lufu].
Topics: Antigens, Bacterial; Culture Media; Dapsone; Electrophoresis; Humans; Immunoblotting; Leprostatic Ag | 2001 |
Effect of peroxidase in complex with basic antileprosy drugs on liver, blood, and functional activity of phagocytes in mice with experimental leprosy.
Topics: Animals; Anti-Inflammatory Agents; Dapsone; Drug Combinations; Horseradish Peroxidase; Leprostatic A | 2001 |
Dapsone-induced methemoglobinemia in leprosy patients.
Topics: Adolescent; Adult; Child; Cytochrome Reductases; Cytochrome-B(5) Reductase; Dapsone; Female; Humans; | 2001 |
Treatment of Hansen's disease.
Topics: Clofazimine; Dapsone; Dermatomycoses; Diagnosis, Differential; Drug Therapy, Combination; Humans; Le | 2002 |
An evaluation of the immune state in leprosy.
Topics: Adult; Animals; Dapsone; Graft vs Host Reaction; Humans; Immunity, Cellular; Leprosy; Lymphocytes; M | 1976 |
Sulphone resistance in leprosy. A review of one hundred proven clinical cases.
Topics: Adolescent; Adult; Animals; Child; Dapsone; Drug Resistance, Microbial; Female; Humans; Leprosy; Mal | 1975 |
Letter: Sulphone resistance in leprosy.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mycobacterium leprae | 1975 |
Letter: Sulphone resistance in leprosy.
Topics: Dapsone; Humans; Leprosy | 1975 |
Long-spacing collagen in skin biopsies from patients with lepromatous leprosy.
Topics: Animals; Collagen; Connective Tissue; Dapsone; Extracellular Space; Granuloma; Humans; Leprosy; Micr | 1975 |
Letter: Prevention of leprosy by acedapsone.
Topics: Acedapsone; Adult; Child; Dapsone; Humans; Leprosy; Micronesia | 1975 |
Controlling the spread of leprosy--some observations on.
Topics: Allied Health Personnel; Antitubercular Agents; Dapsone; Drug Resistance, Microbial; Drug Therapy, C | 1976 |
Rapid test for drug resistance in leprosy.
Topics: Dapsone; Dihydroxyphenylalanine; Drug Resistance, Microbial; Humans; In Vitro Techniques; Isotope La | 1977 |
Demonstration of dapsone in urine and serum by ELISA inhibition.
Topics: Dapsone; Enzyme-Linked Immunosorbent Assay; Humans; Immunoenzyme Techniques; Immunologic Techniques; | 1978 |
Depressive effect of serum from patients with leprosy on mixed lymphocyte reactions. Influence of anti-leprosy treatment.
Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Antibody Specificity; Child; Dapsone; Ethnicity; F | 1975 |
Reliability of dapsone self-administration by leprosy patients in the Rangoon area.
Topics: Dapsone; Humans; Leprosy; Myanmar; Self Administration | 1978 |
The reliability of self-administration of dapsone by leprosy patients in Burma.
Topics: Ambulatory Care; Dapsone; Humans; Leprosy; Myanmar; Patient Compliance; Self Administration; Tablets | 1979 |
The disposition of sulfoxone and solasulfone in leprosy patients.
Topics: Alkanesulfonates; Dapsone; Humans; Leprostatic Agents; Leprosy; Sulfones | 1975 |
Pattern of reactions in leprosy: a clinical appraisal.
Topics: Acute Disease; Adolescent; Adult; Child; Dapsone; Edema; Erythema Nodosum; Female; Humans; Leprosy; | 1977 |
Serum angiotensin-converting enzyme in leprosy and coccidioidomycosis.
Topics: Coccidioidomycosis; Dapsone; Drug Administration Schedule; Erythema Nodosum; Humans; Infarction; Lep | 1977 |
[Leprosy and the nervous system (author's transl)].
Topics: Adult; Antibody Formation; Central Nervous System Diseases; Clofazimine; Dapsone; Diagnosis, Differe | 1979 |
Blood DDS levels and acetylation rates of sulphadimidine in leprosy patients.
Topics: Acetylation; Adolescent; Adult; Dapsone; Drug Resistance, Microbial; Female; Humans; Leprosy; Male; | 1977 |
The prevalence of dapsone-resistant leprosy in Israel.
Topics: Adult; Dapsone; Drug Resistance, Microbial; Female; Humans; Israel; Leprosy; Male; Middle Aged; Myco | 1977 |
Clinical assessment and management of dapsone-resistant leprosy for the field worker.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mycobacterium leprae; Recurrence | 1977 |
Sulphone resistance and its implications.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mycobacterium leprae | 1977 |
Management of sulphone-resistant lepromatous leprosy.
Topics: Clofazimine; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mycobacterium leprae; Thalidomide | 1977 |
Primary dapsone-resistant leprosy.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mycobacterium leprae | 1977 |
Dapsone-resistant leprosy and its implications for leprosy control programmes.
Topics: Dapsone; Drug Resistance, Microbial; Ethiopia; Humans; Leprosy; Mycobacterium leprae | 1977 |
The diagnosis and management of dapsone-resistant leprosy.
Topics: Clofazimine; Dapsone; Diagnosis, Differential; Drug Resistance, Microbial; Humans; Leprosy; Mycobact | 1977 |
Leprosy eradication project of Malta. First published report after 5 years running.
Topics: Adolescent; Adult; Aged; Bacteriological Techniques; Child; Dapsone; Drug Therapy, Combination; Fema | 1977 |
Hydnocarpus oil as an antileprotic agent in footpad technique.
Topics: Animals; Dapsone; Drug Therapy, Combination; Humans; Leprosy; Mice; Mycobacterium leprae; Oils; Seed | 1977 |
The chemotherapy of leprosy from a microbiological standpoint.
Topics: Animals; Dapsone; Drug Evaluation; Drug Resistance, Microbial; Guinea Pigs; Humans; Leprosy; Mice; M | 1977 |
Antibody activity against Mycobacterium leprae antigen 7 during the first year of DDS treatment in lepromatous (BL-LL) leprosy.
Topics: Adolescent; Antibodies, Bacterial; Antigens, Bacterial; BCG Vaccine; Dapsone; Humans; Leprosy; Male; | 1978 |
Primary sulphone resistance. A preliminary report.
Topics: Animals; Child; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mice; Mycobacterium leprae | 1978 |
In vitro resistance test of human leprosy bacilli to anti-leprous drugs.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Isoniazid; Leprostatic Agents; Leprosy; Microbial Sensi | 1977 |
Committee 4: workshop on experimental chemotherapy of leprosy.
Topics: Animals; Antitubercular Agents; Clofazimine; Dapsone; Drug Resistance, Microbial; Leprostatic Agents | 1979 |
Immunology and the therapeutics of leprosy.
Topics: Animals; Antibodies, Bacterial; Antigen-Antibody Complex; Armadillos; Child; Dapsone; Drug Resistanc | 1979 |
[Comparative study of the variable averages and bacilloscopic and morphologic indexes in Virchowian Hansen patients treated with rifampicin and diaminediphenylsulfone].
Topics: Dapsone; Humans; Leprosy; Mycobacterium leprae; Rifampin | 1979 |
Dapsone-resistant leprosy in Ethiopia.
Topics: Dapsone; Drug Resistance, Microbial; Ethiopia; Humans; Leprosy; Microbial Sensitivity Tests; Mycobac | 1979 |
Antibody activity against Mycobacterium leprae antigen 7 in leprosy: studies on variation in antibody content throughout the spectrum and on the effect of DDS treatment and relapse in BT leprosy.
Topics: Antibodies, Bacterial; Antigens, Bacterial; Dapsone; Humans; Leprosy; Mycobacterium leprae; Recurren | 1979 |
Do leprosy patients in Papua New Guinea take their dapsone?
Topics: Dapsone; Female; Humans; Leprosy; Male; Mycobacterium leprae; New Guinea; Patient Compliance | 1979 |
Dapsone alone compared with dapsone plus rifampicin in short-term therapy of lepromatous leprosy.
Topics: Dapsone; Drug Therapy, Combination; Erythema Nodosum; Female; Humans; Leprosy; Malaysia; Male; Mycob | 1977 |
Some characteristics of the action of dapsone on multiplication of Mycobacterium leprae in the mouse.
Topics: Animals; Dapsone; Leprosy; Male; Mice; Mice, Inbred BALB C; Mycobacterium leprae; Time Factors | 1977 |
The treatment of leprosy today and tomorrow: the LEPRA consultation on chemotherapy.
Topics: Clofazimine; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mycobacterium leprae; Patient Com | 1977 |
[Research in the campaign against leprosy (author's transl)].
Topics: Animals; Armadillos; Dapsone; Drug Therapy, Combination; Humans; Isoniazid; Leprosy; Mice; Models, B | 1977 |
Metabolic disposition of dapsone in African leprosy patients.
Topics: Acetylation; Adult; Africa; Dapsone; Female; Humans; Leprosy; Male; Middle Aged; Phenotype | 1979 |
Unusual finding at septoplasty.
Topics: Dapsone; Humans; Leprosy; Male; Middle Aged; Nasal Septum | 1979 |
Calcified abscess in the ulnar nerve in a patient with leprosy. A case report.
Topics: Abscess; Adult; Calcinosis; Dapsone; Drainage; Follow-Up Studies; Humans; Leprosy; Lidocaine; Male; | 1979 |
Workshop on "chemotherapy of leprosy" at the Central Leprosy Teaching and Research Institute, Chengalpattu (Tamil Nadu) on 21 January 1978.
Topics: Clofazimine; Dapsone; Humans; India; Leprosy; Recurrence; Rifampin; Thalidomide | 1979 |
Influence of rifampicin on D.D.S. excretion in urine.
Topics: Adult; Dapsone; Female; Humans; Leprosy; Male; Rifampin | 1979 |
Acedapsone in the prevention of leprosy: field trial in three high prevalence villages in Micronesia.
Topics: Acedapsone; Adult; Child; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Micronesia; Patient | 1979 |
[Chemotherapy of leprosy. I. Sulfones and sulfonamides].
Topics: Dapsone; Drug Resistance, Microbial; Drug Therapy, Combination; Erythema Nodosum; Humans; Leprostati | 1979 |
Organizing a leprosy control programme.
Topics: Attitude to Health; Climate; Dapsone; Financing, Organized; Geography; Humans; India; Leprostatic Ag | 1979 |
A study of patients with erythema nondosum leprosum syndrome.
Topics: Adult; Dapsone; Erythema Nodosum; Female; Humans; Leprosy; Male; Middle Aged | 1979 |
Dapsone treatment and deformities. A retrospective study.
Topics: Adult; Child; Dapsone; Eye Diseases; Foot Deformities, Acquired; Hand Deformities, Acquired; Humans; | 1979 |
News about carcinogens: what's fit to print.
Topics: Animals; Carcinogens; Dapsone; Drug Evaluation, Preclinical; Ethics, Medical; Female; Humans; Inform | 1979 |
Dapsone.
Topics: Dapsone; Humans; Leprosy; Skin Diseases | 1979 |
Activity and effective serum level of repository sulphones (DADDS) in lepromatous leprosy.
Topics: Acedapsone; Adult; Dapsone; Delayed-Action Preparations; Female; Humans; Injections, Intramuscular; | 1979 |
Treatment of steroid dependant cases of recurrent lepra reaction with a combination of thalidomide and clofazimine.
Topics: Adult; Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Leprosy; Male; Recurrence; Steroids; | 1979 |
Irregularity of treatment in leprosy patients: its magnitude and causes.
Topics: Adolescent; Adult; Child; Dapsone; Educational Status; Female; Humans; India; Leprosy; Male; Occupat | 1979 |
Effect of ascorbic acid on blood levels of DDS.
Topics: Ascorbic Acid; Dapsone; Humans; Leprosy; Time Factors | 1979 |
Dapsone resistance in patients with treated lepromatous leprosy.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Leprosy | 1979 |
Variability of urinary dapsone/creatinine concentration ratios in leprosy patients fully compliant with dapsone therapy.
Topics: Adult; Aged; Creatinine; Dapsone; Female; Humans; Leprosy; Male; Middle Aged; Self Administration | 1979 |
Duration of treatment for "disease arrest" of non-lepromatous cases and relapse rate in these patients.
Topics: Adult; Child; Dapsone; Humans; Leprostatic Agents; Leprosy; Time Factors | 1979 |
Lepromatous iridocyclitis diagnosed by anterior chamber paracentesis.
Topics: Adult; Anterior Chamber; Atropine; Biopsy; Dapsone; Humans; Leprosy; Male; Prednisone; Punctures; Ri | 1979 |
Relapse in leprosy.
Topics: Costs and Cost Analysis; Dapsone; Developing Countries; Humans; Leprosy | 1977 |
Serum and tissue lysozyme in leprosy.
Topics: Adolescent; Adult; Aged; Dapsone; Histiocytes; Humans; Leprosy; Middle Aged; Muramidase; Radiation-P | 1977 |
Monitoring self administration of dapsone by patients.
Topics: Ambulatory Care; Creatinine; Dapsone; Humans; Leprosy; Patient Compliance; Self Administration | 1977 |
A comparison of low and conventional dosages of dapsone in the treatment of lepromatous leprosy.
Topics: Dapsone; Humans; Lepromin; Leprosy; Male; Sulfones | 1977 |
Dapsone in wheat flour as a possible method of therapy in leprosy. A laboratory report.
Topics: Administration, Oral; Adolescent; Adult; Aged; Bread; Child; Child, Preschool; Dapsone; Female; Flou | 1977 |
Leprosy and the rheumatoid factor.
Topics: Clofazimine; Dapsone; Humans; Leprosy; Rheumatoid Factor | 1978 |
Encouraging results from DDS urine analysis among registered leprosy patients in Wangas, Kenya: an exception that challenges the rule.
Topics: Dapsone; Female; Humans; Kenya; Leprosy; Male; Patient Compliance | 1978 |
Irregularity of Dapsone intake in infectious leprosy patients attending an urban treatment centre--its magnitude and causes.
Topics: Dapsone; Female; Humans; Leprosy; Male; Patient Compliance; Self Administration; Socioeconomic Facto | 1978 |
Combined therapy in leprosy. Background and findings.
Topics: Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Leprostatic Agents; Lepros | 1978 |
Proven primary dapsone resistance in leprosy--a case report.
Topics: Child; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Male | 1978 |
The time interval between the start of anti-leprosy treatment and the development of reactions in borderline patients.
Topics: Dapsone; Humans; Leprosy; Time Factors | 1978 |
Combined therapy in principle and practice for the control of dapsone resistance.
Topics: Dapsone; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy | 1978 |
Srategy of leprosy control.
Topics: BCG Vaccine; Dapsone; Erythema Nodosum; Humans; Leprostatic Agents; Leprosy; Population Surveillance | 1978 |
Leprosy: A report of two cases in children.
Topics: Child; Dapsone; Dominican Republic; Guyana; Humans; Hypesthesia; Leprosy; Male; Mycobacterium Infect | 1978 |
Lucio's phenomenon and diffuse nonnodular lepromatous leprosy.
Topics: Adult; Dapsone; Erythema Nodosum; Female; Humans; Ischemia; Leprosy; Lymphopenia; Male; Middle Aged; | 1978 |
Use of a common Indian herb "Mandukaparni" in the treatment of leprosy (preliminary report).
Topics: Adult; Dapsone; Humans; India; Leprosy; Middle Aged; Plants, Medicinal | 1978 |
Can the dapsone-creatinine ratio in urine be used to monitor therapy in rural areas?
Topics: Creatinine; Dapsone; Humans; India; Leprosy | 1978 |
Reversal reactions in lepromatous leprosy following transfer factor therapy.
Topics: Adult; Aged; Dapsone; Female; Humans; Immunotherapy; Lepromin; Leprosy; Male; Middle Aged; Skin; Tra | 1978 |
Activity of derivatives and analogs of dapsone against Mycobacterium leprae.
Topics: Animals; Dapsone; Leprosy; Male; Mice; Mice, Inbred BALB C | 1978 |
Kellersberger Memorial Lecture 1978. Leprosy control--present position and future prospects.
Topics: BCG Vaccine; Dapsone; Drug Resistance; Humans; Leprosy | 1978 |
Development of Hodgkin's disease in a patient with leprosy.
Topics: Adult; Antineoplastic Agents; Cholestasis; Dapsone; Drug Therapy, Combination; Hodgkin Disease; Huma | 1978 |
Study of sulphone resistance in leprosy patients in India.
Topics: Animals; Dapsone; Drug Evaluation; Drug Resistance, Microbial; Humans; India; Leprosy; Mice; Mycobac | 1976 |
Bactericidal action of dapsone against Mycobacterium leprae in mice.
Topics: Animals; Dapsone; Foot; Leprosy; Male; Mice; Mice, Inbred BALB C; Mycobacterium leprae; Time Factors | 1976 |
Defective leukotaxis in patients with lepromatous leprosy.
Topics: Chemotaxis; Complement Inactivator Proteins; Dapsone; Hot Temperature; Humans; Hypersensitivity, Del | 1976 |
Dapsone chemotherapy of Mycobacterium leprae infection of the neonatally thymectomized Lewis rat.
Topics: Animals; Animals, Newborn; Dapsone; Disease Models, Animal; Female; Leprosy; Male; Mice; Mice, Inbre | 1976 |
Clofazimine in the treatment of dapsone resistant leprosy.
Topics: Clofazimine; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mycobacterium leprae | 1976 |
Susceptibility of thymectomized and irradiated mice to challenge with several organisms and the effect of dapsone on infection with Mycobacterium leprae.
Topics: Animals; Bacteriological Techniques; Cytoplasm; Dapsone; Hindlimb; Immunization; Immunization, Secon | 1975 |
Antileprosy measures in Bombay, India: an analysis of 10 years' work.
Topics: Communicable Disease Control; Cost-Benefit Analysis; Dapsone; Humans; India; Leprosy; Retrospective | 1976 |
Acedapsone treatment of leprosy patients: response versus drug disposition.
Topics: Acedapsone; Acetylation; Adult; Child; Dapsone; Female; Humans; Leprosy; Male; Phenotype; Sulfametha | 1977 |
Leprosy--a social disease.
Topics: Attitude to Health; Bacterial Vaccines; BCG Vaccine; Dapsone; Humans; India; Leprosy; Patient Compli | 1977 |
How effective is the treatment of leprosy?
Topics: Dapsone; Humans; Leprosy | 1977 |
[Borderline-type leprosy].
Topics: Adult; Dapsone; Female; Humans; Leprosy; Methylprednisolone | 1977 |
The effect on the multiplication of Mycobacterium leprae of irregular administration of dapsone to mice. Results of the total minimal inhibitory test.
Topics: Animals; Dapsone; Leprosy; Mice | 1977 |
[Lepra lepromotosa].
Topics: Adult; Dapsone; Humans; Leprosy; Male; Skin; Skin Manifestations | 1977 |
Regularity of dapsone intake by leprosy patients attending urban treatment centre.
Topics: Adolescent; Adult; Creatinine; Dapsone; Female; Humans; Leprosy; Male; Middle Aged; Outpatient Clini | 1977 |
Relaspe in leprosy.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Recurrence | 1977 |
The significance of the local sweat response in assessing the progress of leprosy.
Topics: Adolescent; Adult; Carbachol; Dapsone; Female; Humans; Leprosy; Male; Middle Aged; Prognosis; Sensat | 1976 |
Lepromatous leprosy: dapsone resistance.
Topics: Clofazimine; Dapsone; Drug Resistance, Microbial; Female; Foot Deformities, Acquired; Humans; Lepros | 1976 |
The diagnosis and treatment of leprosy.
Topics: Biopsy; Clofazimine; Dapsone; Erythema Nodosum; Humans; Immunotherapy; Leprosy; Recurrence; Rifampin | 1976 |
Weekly self-medication of leprosy patients monitored by DDS/creatinine ratios in urines.
Topics: Creatinine; Dapsone; Female; Humans; Leprosy; Male; Tanzania | 1976 |
Tuberculoid leprosy.
Topics: Adult; Dapsone; Diagnosis, Differential; Female; Humans; Leprosy; Rifampin; Skin Manifestations; Tub | 1976 |
Leprosy in northern Nigeria.
Topics: Dapsone; Leprosy; Nigeria | 1976 |
Treatment of Hansen's disease.
Topics: Chloroquine; Clofazimine; Dapsone; Drug Resistance, Microbial; Erythema Nodosum; Humans; Leprosy; Pr | 1976 |
A trial of long-acting sulphonamide R.O. 4-4393 (fanasil) in treatment of cases of lepromatous leprosy with repeated E.N.L.
Topics: Dapsone; Erythema Nodosum; Humans; Leprosy; Sulfonamides | 1976 |
Transformation from lepromatous to borderline leprosy under clofazimine therapy.
Topics: Adult; Clofazimine; Dapsone; Humans; Leprosy; Male; Skin | 1976 |
Reactive episodes in borderline lepromatous leprosy--a case report.
Topics: Adult; Dapsone; Humans; Leprosy; Male | 1976 |
Inactivation and relapse in bacterio-negative cases of leprosy under sulphone therapy: a 4 1/2 years follow-up.
Topics: Dapsone; Female; Follow-Up Studies; Humans; Leprosy; Male; Recurrence | 1976 |
An evaluation of the self administration of DDS in Gudiyatham Taluk.
Topics: Adult; Creatinine; Dapsone; Evaluation Studies as Topic; Female; Health Education; Humans; India; Le | 1976 |
Clinical trial with clofazimine in leprosy.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Child; Clofazimine; Dapsone; Drug Therapy, Combination; | 1976 |
Experiences in treatment of histoid cases with clofazimine.
Topics: Clofazimine; Dapsone; Humans; Leprosy | 1976 |
Side effects of clofazimine therapy.
Topics: Adolescent; Adult; Clofazimine; Dapsone; Female; Humans; Ichthyosis; Isoniazid; Leprosy; Male; Skin | 1976 |
Clinical recognition and therapeutic confirmation of sulphone resistant leprosy patients.
Topics: Adult; Dapsone; Drug Resistance, Microbial; Female; Humans; Leprosy; Male | 1976 |
[New drugs in the treatment of leprosy].
Topics: Dapsone; Drug Combinations; Drug Evaluation; Humans; Isoniazid; Isonicotinic Acids; Leprosy; Prothio | 1976 |
Immunodeficiency in leprosy.
Topics: Agglutination Tests; B-Lymphocytes; Blood Transfusion; Body Temperature; Cytotoxicity Tests, Immunol | 1975 |
The histopathology of lepromatous leprosy in the nose.
Topics: Biopsy; Dapsone; Humans; India; Leprosy; Macrophages; Mycobacterium leprae; Nasal Mucosa; Nose Disea | 1975 |
Viability of Myco. leprae in the skin and bone marrow of patients with lepromatous leprosy while on dapsone or lamprene.
Topics: Bone Marrow; Clofazimine; Dapsone; Humans; Leprosy; Mycobacterium leprae; Skin | 1975 |
Dapsone metabolism in patients with dapsone-resistant leprosy.
Topics: Acetylation; Dapsone; Drug Resistance; Female; Humans; Leprosy; Male; Metabolic Clearance Rate; Myco | 1975 |
Lepromatous leprosy in the nose after one year of dapsone treatment: clinical and bacteriological findings.
Topics: Adult; Child; Dapsone; Drug Evaluation; Follow-Up Studies; Humans; Leprosy; Mycobacterium leprae; No | 1975 |
Lepromatous leprosy in the nose after one year of dapsone treatment: histopathological findings.
Topics: Dapsone; Humans; Leprosy; Mycobacterium leprae; Nasal Bone; Nasal Septum; Nose Diseases | 1975 |
Multicentre controlled comparative trial of clofazimine and dapsone in low dosages.
Topics: Clofazimine; Dapsone; Dose-Response Relationship, Drug; Drug Evaluation; Humans; Leprosy; Mycobacter | 1975 |
Importance of nasal lesions in early lepromatous leprosy.
Topics: Dapsone; Humans; Leprosy; Mycobacterium leprae; Nasal Mucosa; Nose Diseases; Rifampin | 1975 |
Minimal inhibitory concentration of dapsone for Mycobacterium leprae in rats.
Topics: Animals; Dapsone; Diet; Female; Leprosy; Male; Microbial Sensitivity Tests; Mycobacterium leprae; Ra | 1975 |
The case for invisible leprosy.
Topics: Child; Dapsone; Diagnosis, Differential; Erythema; Female; Humans; Israel; Leprosy; Periodicity; Rem | 1975 |
Treatment of neuritis in borderline leprosy with rifampicin and corticosteroids--a pilot trial.
Topics: Adult; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Leprosy; Male; Neuritis; Pil | 1975 |
Preliminary experience with combined therapy using rifampicin and isoprodian (L73A).
Topics: Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Isonicotinic Acids; Lepros | 1975 |
Treatment of leprosy with rifampicin and isoprodian in 38 patients at St. Thomas Hospital, Chetput, Sout India.
Topics: Adolescent; Adult; Child; Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Ind | 1975 |
Thalidomide in lepra reaction.
Topics: Dapsone; Humans; Leprosy; Thalidomide | 1975 |
Passive transfer of immunity into leprosy patients by transfusion of lymphocytes and by transfusion of Lawrence's transfer factor.
Topics: Adolescent; Adult; Blood Transfusion; Dapsone; Drug Tolerance; Female; Humans; Immunity, Maternally- | 1975 |
The effect of rifampicin on dapsone metabolism.
Topics: Acetylation; Dapsone; Half-Life; Humans; Leprosy; Protein Binding; Rifampin; Sulfamethazine | 1975 |
Erythema nodosum leprosum in Nigeria.
Topics: Adolescent; Child; Dapsone; Erythema Nodosum; Humans; Leprosy; Male; Nigeria | 1975 |
Letter: Dapsone dosage and drug resistance.
Topics: Child; Child, Preschool; Dapsone; Drug Resistance, Microbial; Humans; Leprosy | 1975 |
The drug treatment of leprosy.
Topics: Acute Disease; Adrenal Cortex Hormones; Aniline Compounds; Clofazimine; Dapsone; Drug Therapy, Combi | 1975 |
Use of "Novolep", a by-product of D.D.S., for the treatment of trophic ulcers (planter) in leprosy.
Topics: Adult; Dapsone; Drug Combinations; Female; Foot Dermatoses; Humans; Iron; Leg Ulcer; Leprostatic Age | 1975 |
Dapsone induced motor polyneuropathy.
Topics: Adolescent; Adult; Dapsone; Humans; Leprosy; Male; Middle Aged; Neuritis; Peripheral Nervous System | 1992 |
Dapsone syndrome in Vanuatu: a high incidence during multidrug treatment (MDT) of leprosy.
Topics: Adolescent; Adult; Chemical and Drug Induced Liver Injury; Clofazimine; Dapsone; Drug Eruptions; Dru | 1992 |
Leprosy in French Polynesia. The possible impact of multidrug therapy on epidemiological trends.
Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Ethionamide; Humans; Leprosy; Polynesia; Rifampin | 1992 |
An experimental study to evaluate the bactericidal activity of ofloxacin against an established Mycobacterium leprae infection.
Topics: Animals; Dapsone; Disease Models, Animal; Drug Therapy, Combination; Leprosy; Mice; Mice, Nude; Myco | 1992 |
Detection of Mycobacterium leprae and the potential for monitoring antileprosy drug therapy directly from skin biopsies by PCR.
Topics: Anti-Bacterial Agents; Biopsy; Clofazimine; Dapsone; DNA Probes; DNA, Bacterial; Drug Therapy, Combi | 1992 |
Relapses in leprosy patients after release from dapsone monotherapy; experience in the leprosy control program of the all Africa Leprosy and Rehabilitation Training Center (ALERT) in Ethiopia.
Topics: Adolescent; Adult; Child; Child, Preschool; Dapsone; Ethiopia; Eye Infections, Bacterial; Female; Hu | 1992 |
Ambulatory treatment of multibacillary leprosy with a regimen of 8 months duration.
Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Ethionamide; Humans; Leprostatic Agents; Leprosy | 1992 |
Eight years of follow-up of paucibacillary patients treated with short-course regimens.
Topics: Dapsone; Drug Therapy, Combination; Follow-Up Studies; Humans; Leprosy; Recurrence; Rifampin | 1992 |
Agranulocytosis during multidrug therapy (MDT) of leprosy.
Topics: Adult; Agranulocytosis; Dapsone; Female; Humans; Leprosy | 1992 |
Multidrug therapy in multibacillary leprosy; experience in an urban leprosy center.
Topics: Dapsone; Drug Therapy, Combination; Humans; India; Lepromin; Leprostatic Agents; Leprosy; Patient Co | 1992 |
Treatment of smear negative MB patients who had received previous dapsone monotherapy.
Topics: Dapsone; Humans; Leprosy | 1992 |
Histopathological findings in the iris of dapsone treated leprosy patients.
Topics: Adult; Aged; Aged, 80 and over; Atrophy; Dapsone; Female; Humans; Iris; Iritis; Leprosy; Male; Middl | 1990 |
[Use of tuftsin in experimental leprosy].
Topics: Animals; Cell Line; Dapsone; Leprosy; Mice; Mice, Inbred CBA; Mycobacterium leprae; Rifampin; Tuftsi | 1991 |
Risk of relapse among non-lepromatous patients released from treatment after dapsone monotherapy.
Topics: Adolescent; Adult; Child; Child, Preschool; Dapsone; Female; Humans; Infant; Leprosy; Male; Recurren | 1991 |
Reply: recommending drug regimens to smear negative MB cases after prolonged dapsone monotherapy.
Topics: Dapsone; Humans; Leprosy; Mycobacterium leprae | 1991 |
The response to chemotherapy of serum Mycobacterium leprae-specific antigen in multibacillary leprosy patients.
Topics: Antibodies, Bacterial; Antigens, Bacterial; Carbohydrate Sequence; Clofazimine; Dapsone; Drug Therap | 1991 |
In vitro and in vivo effects of N-methyl-3,5-dichloro-benzylamine hydrochloride on Mycobacterium leprae.
Topics: Animals; Armadillos; Benzylamines; Dapsone; Leprostatic Agents; Leprosy; Mice; Mice, Inbred BALB C; | 1991 |
Effect of dapsone on haemoglobin concentration in patients with leprosy.
Topics: Adolescent; Adult; Aged; Child; Dapsone; Female; Glucosephosphate Dehydrogenase Deficiency; Hemoglob | 1991 |
Longitudinal study on relapses of leprosy in Polynesian multibacillary patients on dapsone monotherapy between 1946 and 1970.
Topics: Dapsone; Humans; Leprosy; Longitudinal Studies; Polynesia; Probability; Recurrence; Risk | 1991 |
A retrospective study on seven years of multiple drug treatment for paucibacillary and multibacillary leprosy, in Bayara General Hospital, Nigeria.
Topics: Adolescent; Adult; Clofazimine; Dapsone; Drug Administration Schedule; Drug Resistance, Microbial; D | 1991 |
Impact of multidrug therapy on the treatment and control of leprosy.
Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Global Health; Humans; Leprosy; Patient Compliance; | 1991 |
Cytogenetic studies in leprosy patients before and after chemotherapy.
Topics: Adult; Aged; Cell Cycle; Cells, Cultured; Chromosome Aberrations; Dapsone; Female; Follow-Up Studies | 1991 |
The activity of amoxicillin plus clavulanic acid against Mycobacterium leprae in mice.
Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Animals; Clavulanic Acids; Dapsone; Drug | 1991 |
Fixed duration MDT in paucibacillary leprosy.
Topics: Adolescent; Adult; Aged; Child; Dapsone; Drug Therapy, Combination; Female; Humans; Leprosy; Leprosy | 1991 |
The reduction of the leprosy endemicity in northeastern Zaire 1975/1989.
Topics: Dapsone; Democratic Republic of the Congo; Humans; Leprosy; Prevalence | 1990 |
[Endemic leprosy in the People's Republic of Congo. An epidemiological and behavioral analysis].
Topics: Adolescent; Adult; Aged; Case-Control Studies; Congo; Cross-Sectional Studies; Culture; Dapsone; Fem | 1990 |
Selection of MDT strategies through epidemiometric modeling.
Topics: Computer Simulation; Cost-Benefit Analysis; Dapsone; Drug Therapy, Combination; Humans; Incidence; L | 1990 |
Effect of simultaneous administration of interferon-gamma and chemotherapy against Mycobacterium leprae in experimental infection in nude mice.
Topics: Animals; Combined Modality Therapy; Dapsone; Drug Therapy, Combination; Interferon-gamma; Leprosy; M | 1990 |
In vitro and in vivo experiments with the new inhibitor of mycobacterium leprae brodimoprim alone and in combination with dapsone.
Topics: Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Dapsone; Drug Interactions; L | 1990 |
[Late reversal reactions in leprosy].
Topics: Clofazimine; Dapsone; Drug Combinations; Ethionamide; Female; Humans; Leprosy; Male; Recurrence; Rif | 1990 |
Primary dapsone-resistant Hansen's disease in California. Experience with over 100 Mycobacterium leprae isolates.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; California; Child; Dapsone; Drug Resistance, Mi | 1990 |
The chemotherapy of leprosy. Part 1.
Topics: Animals; Clofazimine; Dapsone; Drug Resistance, Microbial; Drug Therapy, Combination; Ethionamide; H | 1990 |
[Drugs used in tuberculosis and leprosy].
Topics: Administration, Oral; Antibiotics, Antitubercular; Clofazimine; Dapsone; Humans; Injections, Intramu | 1990 |
Are dapsone hypersensitivity reactions dose related?
Topics: Child; Dapsone; Dose-Response Relationship, Drug; Drug Hypersensitivity; Humans; Leprosy; Male | 1990 |
Methods of leprosy prevention.
Topics: Dapsone; Humans; Leprosy | 1990 |
Effect of three-year multidrug therapy in multibacillary leprosy patients.
Topics: Adult; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Leprosy; Leprosy, Borderline | 1990 |
Relapses in multibacillary leprosy.
Topics: Dapsone; Humans; Leprosy; Recurrence | 1990 |
Ethionamide, prothionamide and thiacetazone self-administration. Studies of patient compliance using isoniazid-marked formulations.
Topics: Adolescent; Adult; Aged; Dapsone; Drug Therapy, Combination; Ethionamide; Female; Humans; Isoniazid; | 1986 |
Increased incidence in leprosy of hypersensitivity reactions to dapsone after introduction of multidrug therapy.
Topics: Adolescent; Adult; Aged; Child; Cohort Studies; Dapsone; Drug Hypersensitivity; Drug Therapy, Combin | 1989 |
Effect of suppressor cells on antibody producing cells in mice infected with Mycobacterium leprae.
Topics: Animals; Antibody-Producing Cells; Dapsone; Hemolytic Plaque Technique; Immunoglobulin G; Immunoglob | 1989 |
Pattern of leprosy disabilities in Gorakhpur (Uttar Pradesh).
Topics: Adolescent; Adult; Age Factors; Aged; Child; Dapsone; Disabled Persons; Female; Humans; India; Lepro | 1989 |
Dapsone induced psychosis.
Topics: Adult; Dapsone; Female; Humans; Leprosy; Psychoses, Substance-Induced | 1989 |
Study of multidrug therapy in paucibacillary leprosy.
Topics: Administration, Oral; Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lepr | 1989 |
Isoprodian and rifampicin in the treatment of leprosy: a descriptive evaluation of therapy durations in 475 Paraguayan leprosy patients.
Topics: Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Isonicotinic Acids; Lepros | 1989 |
Antagonism between dapsone and rifampicin in experimental Mycobacterium leprae infections in mice.
Topics: Animals; Dapsone; Drug Interactions; Drug Therapy, Combination; Female; Leprosy; Mice; Mycobacterium | 1989 |
PGL-I antigen and antibody detection in leprosy patients: evolution under chemotherapy.
Topics: Antibodies, Bacterial; Antigens, Bacterial; Dapsone; Drug Therapy, Combination; Glycolipids; Humans; | 1989 |
Bacillaemia in leprosy and effect of multidrug therapy.
Topics: Adolescent; Adult; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Leprosy; Leprosy | 1989 |
Self-administered drug compliance in Nepali leprosy patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Dapsone; Female; Humans; Leprosy; Male; Middle Ag | 1989 |
Humoral immune responses in dapsone treated M. leprae infected mice.
Topics: Animals; Antibody Formation; Dapsone; Immunoglobulin G; Leprosy; Mice | 1989 |
Impact of multidrug therapy on leprosy in Baroda district (Gujarat).
Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Humans; India; Leprosy; National Health Programs; P | 1989 |
Evaluation of two multidrug regimen in hospitalised multibacillary cases.
Topics: Clofazimine; Dapsone; Drug Evaluation; Drug Resistance, Microbial; Drug Therapy, Combination; Hospit | 1989 |
A study into bacteriological positivity and treatment of beggar leprosy patients.
Topics: Biopsy; Dapsone; Humans; Ill-Housed Persons; India; Leper Colonies; Leprosy; Skin | 1989 |
Relapses in paucibacillary patients after treatment with three short-term regimens containing rifampin.
Topics: Adult; Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Lepromin; L | 1989 |
Leprosy in infants--report of two cases.
Topics: Dapsone; Female; Humans; Infant; Leprosy; Rifampin | 1989 |
Comments on an editorial by B. R. Chatterjee "On Multi-Drug Combinations in the Treatment of Leprosy".
Topics: Animals; Clofazimine; Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Humans; Ison | 1989 |
Drug resistance and multi-drug therapy in leprosy.
Topics: Animals; Clofazimine; Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lepr | 1989 |
Dapsone drug compliance study among leprosy patients: a comparison between qualitative and quantitative methods.
Topics: Creatinine; Dapsone; Female; Humans; Leprosy; Male; Patient Compliance; Random Allocation; Self Admi | 1989 |
Rate and time distribution of relapses in multibacillary leprosy.
Topics: Dapsone; Humans; Leprosy; Recurrence; Retrospective Studies; Time Factors | 1989 |
Short-term multidrug therapy in multibacillary leprosy--review of 80 cases in two provinces of China (1983-1988).
Topics: Adult; China; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Leprostatic Agents; L | 1989 |
Demonstration of antidapsone antibody in leprosy patients.
Topics: Antibodies; Antibody Formation; Cross Reactions; Dapsone; Humans; Leprosy | 1989 |
A follow up of T-cell subsets and of anti-M. leprae antibody titer as measured by the FLA-ABS test in Melanesian leprosy patients under polychemotherapy.
Topics: Adolescent; Adult; Antibodies, Bacterial; Child; Clofazimine; Dapsone; Drug Therapy, Combination; Er | 1986 |
Hypersensitivity reaction to dapsone.
Topics: Adult; Dapsone; Dermatitis, Exfoliative; Drug Hypersensitivity; Humans; Leprosy; Male; Registries | 1986 |
Dapsone-induced neuropathy compounds Hansen's disease nerve damage: an electrophysiological study in tuberculoid patients.
Topics: Adolescent; Adult; Dapsone; Female; Humans; Leprosy; Male; Middle Aged; Motor Neurons; Neural Conduc | 1987 |
Dapsone neuropathy--report of three cases and pathologic features of a motor nerve.
Topics: Adolescent; Adult; Biopsy; Dapsone; Female; Humans; Leprosy; Male; Motor Neurons; Neural Conduction; | 1987 |
Instrumental variables in the evaluation of diagnostic test procedures when the true disease state is unknown.
Topics: Dapsone; Enzyme-Linked Immunosorbent Assay; Hemagglutination Tests; Humans; Leprosy; Patient Complia | 1988 |
Activity of ofloxacin against Mycobacterium leprae in the mouse.
Topics: Animals; Anti-Bacterial Agents; Dapsone; Female; Leprosy; Mice; Mycobacterium leprae; Norfloxacin; O | 1988 |
Infectivity of secondary dapsone-resistant cases.
Topics: Adult; Dapsone; Drug Resistance, Microbial; Female; Humans; Leprosy; Male; Mycobacterium leprae | 1988 |
Influence of acetylator phenotype of the leprosy patient on the emergence of dapsone resistant leprosy.
Topics: Acetylation; Dapsone; Drug Resistance, Microbial; Female; Half-Life; Humans; Leprosy; Male; Mycobact | 1988 |
[Effect of rifampicin, clofazimine and dapsone in treating 296 cases of multibacillary leprosy].
Topics: Adolescent; Adult; Aged; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Leprosy; M | 1987 |
The first joint THELEP-Sasakawa Memorial Health Foundation workshop on experimental chemotherapy of leprosy.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Isoniazid; Leprosy; Mycobacterium leprae; Mycobacterium | 1987 |
Leprosy of the head and neck.
Topics: Dapsone; Ear, External; Humans; Leprosy; Male; Middle Aged; Mouth; Nasal Mucosa | 1987 |
[Epidemiology of leprosy in Guadalupe between 1970 and 1983].
Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Dapsone; Drug Resistance; Humans; Inf | 1985 |
Lactate dehydrogenase isoenzymes in leprosy patients on multi drug therapy--a preliminary report.
Topics: Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Humans; Isoenzymes; L-Lactate Dehy | 1988 |
Certain aspects of dapsone metabolism in leprosy patients as studied by high performance liquid chromatography (HPLC) and qualitative screening tests.
Topics: Chromatography, High Pressure Liquid; Dapsone; Enzyme-Linked Immunosorbent Assay; Hemagglutination I | 1988 |
A clinico-pathological study of multidrug regimen in paucibacillary leprosy.
Topics: Adolescent; Adult; Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; | 1988 |
Comparative study of different drug compliance tests available in leprosy.
Topics: Adult; Dapsone; Humans; Leprosy; Metabolic Clearance Rate; Patient Compliance; Reagent Strips; Saliv | 1988 |
Leprosy control based on multi drug treatment in India.
Topics: Allied Health Personnel; Clofazimine; Dapsone; Data Collection; Drug Administration Schedule; Drug T | 1988 |
Tetanus in leprosy patient (II).
Topics: Dapsone; Humans; Knee Injuries; Leprosy; Male; Middle Aged; Seizures; Skin Ulcer; Tetanus | 1988 |
Primary hyperpigmented cutaneous lesions in tuberculoid leprosy.
Topics: Adult; Dapsone; Drug Therapy, Combination; Humans; Leprosy; Leprosy, Tuberculoid; Male; Pigmentation | 1988 |
Multidrug therapy in hospitalised leprosy cases.
Topics: Adult; Clofazimine; Dapsone; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Humans; | 1988 |
[Guinea: detection of leprosy and treatment by polychemotherapy].
Topics: Africa, Western; Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Leprosy; Male; Rif | 1988 |
The actual leprosy situation within Katsina State, Nigeria.
Topics: Dapsone; Humans; Leprosy; Nigeria | 1988 |
On multi-drug combinations in the treatment of leprosy.
Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Ethionamide; Humans; Leprosy; Rifampin | 1988 |
Drug compliance among self-motivated leprosy patients.
Topics: Dapsone; Female; Humans; Leprosy; Male; Motivation; Patient Compliance; Patients | 1988 |
Paucibacillary leprosy: a comparative study of different schedules of multidrug therapy.
Topics: Adult; Clofazimine; Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lepros | 1988 |
Pattern of relapses in pauci-bacillary leprosy patients treated with M.D.T. (W.H.O. 1982).
Topics: Dapsone; Drug Therapy, Combination; Female; Humans; Leprosy; Male; Recurrence; Rifampin; Sex Factors | 1988 |
Multidrug therapy in paucibacillary leprosy--a five year experience.
Topics: Adolescent; Adult; Child; Dapsone; Drug Therapy, Combination; Female; Humans; Leprosy; Male; Prospec | 1988 |
Characteristics of the multiplication of dapsone-resistant strains of Mycobacterium leprae in mice. Subcommittee on Clinical Trials of the C hemotherapy of Leprosy (THELEP) Scientific Working Group of UNDP/World Bank/WHO Special Programme for Research and
Topics: Animals; Dapsone; Drug Resistance, Microbial; Leprosy; Mice; Mycobacterium leprae | 1988 |
Concepts behind the development of multiple drug therapy regimens in leprosy.
Topics: Dapsone; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy; | 1986 |
Primary dapsone resistance in multibacillary leprosy among Nepalese children.
Topics: Adolescent; Child; Child, Preschool; Dapsone; Drug Resistance, Microbial; Female; Humans; Leprosy; M | 1987 |
Concepts behind the development of multiple drug therapy regimens in leprosy.
Topics: Dapsone; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy; | 1986 |
Survey of primary dapsone-resistant leprosy.
Topics: Adolescent; Adult; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Middle Aged; Mycobacterium | 1986 |
Primary and secondary dapsone resistance of M. leprae in Martinique, Guadeloupe, New Caledonia, Tahiti, Senegal, and Paris between 1980 and 1985.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Martinique; Mycobacterium leprae; New Caledoni | 1987 |
Drug susceptibility testing of Mycobacterium leprae.
Topics: Administration, Oral; Animals; Dapsone; Drug Resistance, Microbial; Leprosy; Mice; Microbial Sensiti | 1987 |
Detection of persisting Mycobacterium leprae by inoculation of the neonatally thymectomized rat.
Topics: Animals; Animals, Newborn; Dapsone; Humans; Leprosy; Mice; Mice, Inbred BALB C; Mycobacterium leprae | 1987 |
The neonatally thymectomized rat as a model of the lepromatous patient.
Topics: Animals; Animals, Newborn; Dapsone; Disease Models, Animal; Humans; Immunotherapy; Leprosy; Mice; My | 1987 |
Leprosy in Singapore.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Dapsone; Drug Resistance, Microbial; Female; Humans; Le | 1987 |
[Dapsone-induced photodermatitis in a patient with leprosy].
Topics: Dapsone; Humans; Leprosy; Male; Middle Aged; Photosensitivity Disorders | 1988 |
Influence of once-monthly rifampicin and daily clofazimine on the pharmacokinetics of dapsone in leprosy patients in Nigeria.
Topics: Adolescent; Adult; Aged; Clofazimine; Dapsone; Drug Administration Schedule; Drug Interactions; Drug | 1988 |
A field trial among leprosy patients in Nigeria with depot injections of dapsone and monoacetyldapsone.
Topics: Abscess; Adipose Tissue; Adult; Anti-Infective Agents; Dapsone; Delayed-Action Preparations; Female; | 1988 |
Diagnosis of leprosy.
Topics: Clofazimine; Dapsone; Diagnosis, Differential; Drug Combinations; Humans; Leprosy; Rifampin | 1988 |
Drug interaction during multidrug regimens for treatment of leprosy.
Topics: Clofazimine; Dapsone; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Hu | 1988 |
A borderline leprosy lesion on the palate: a case report.
Topics: Dapsone; Female; Humans; Leprosy; Middle Aged; Mouth Mucosa; Palate; Prednisolone; Rifampin | 1988 |
Pharmacokinetics of aspirin and chloramphenicol in normal and leprotic patients before and after dapsone therapy.
Topics: Adult; Aspirin; Chloramphenicol; Dapsone; Drug Interactions; Female; Half-Life; Humans; Leprosy; Mal | 1988 |
Preliminary appraisal of a WHO-recommended multiple drug regimen in paucibacillary leprosy patients in Malawi.
Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Dapsone; Drug Therapy, Combination; E | 1988 |
Contribution of relapses to total infection sources of leprosy in Guadeloupe.
Topics: Adult; Child; Dapsone; Female; Humans; Leprosy; Male; Recurrence; West Indies | 1987 |
Dapsone poisoning.
Topics: Adult; Dapsone; Female; Humans; Leprosy; Suicide, Attempted | 1987 |
Treatment of paucibacillary leprosy by WHO regimen.
Topics: Adolescent; Adult; Child; Dapsone; Drug Combinations; Female; Humans; Leprosy; Male; Middle Aged; Ri | 1987 |
A simple urine spot test for monitoring dapsone self-administration in leprosy treatment.
Topics: Dapsone; Humans; Leprosy; Patient Compliance; Self Administration | 1986 |
Susceptibility of strains of Mycobacterium leprae isolated prior to 1977 from patients with previously untreated lepromatous leprosy.
Topics: Animals; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mice; Mycobacterium leprae; Time Fact | 1986 |
[Sulfone-resistance of Mycobacterium leprae--monotherapy with diaminodiphenylsulfone--the value of triple-drug combinations].
Topics: Clofazimine; Dapsone; Drug Resistance, Microbial; Drug Therapy, Combination; Humans; Leprosy; Mycoba | 1986 |
Clofazimine-resistant M. leprae.
Topics: Animals; Clofazimine; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mice; Mycobacterium lepr | 1986 |
Relapse rates in lepromatous leprosy according to treatment regularity.
Topics: Dapsone; Humans; Leprosy; Mycobacterium leprae; Recurrence; Skin; Time Factors | 1986 |
Antibodies to phenolic glycolipid-1 and to whole Mycobacterium leprae in leprosy patients: evolution during therapy.
Topics: Antibodies, Bacterial; Antigens, Bacterial; Clofazimine; Dapsone; Drug Therapy, Combination; Ethiona | 1986 |
Combined clofazimine- and dapsone-resistant leprosy. A case report.
Topics: Adult; Animals; Clofazimine; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Male; Mice; Mycob | 1986 |
Survey for primary dapsone resistance in Cuba.
Topics: Animals; Cuba; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mice; Mycobacterium leprae | 1986 |
Activities of pefloxacin and ciprofloxacin against Mycobacterium leprae in the mouse.
Topics: Animals; Ciprofloxacin; Dapsone; Female; Half-Life; Kinetics; Leprosy; Mice; Mycobacterium leprae; N | 1987 |
[Therapy of leprosy today].
Topics: Clofazimine; Dapsone; Drug Resistance; Drug Therapy, Combination; Humans; Leprostatic Agents; Lepros | 1987 |
Comparison of three regimens containing rifampin for treatment of paucibacillary leprosy patients.
Topics: Adult; Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; | 1987 |
Centelia asciatica linn (Thankuni) in the treatment of leprosy.
Topics: Bangladesh; Dapsone; Humans; Leprosy; Plant Extracts; Plants, Medicinal | 1986 |
Preliminary evaluation of the effect of WHO-MDT on disabilities in leprosy patients in Malaŵi (Central Africa).
Topics: Dapsone; Drug Therapy, Combination; Humans; Leprosy; Malawi; Rifampin | 1986 |
Combined chemotherapy of multibacillary leprosy of 6 months' duration.
Topics: Adolescent; Adult; Child; Child, Preschool; Clofazimine; Dapsone; Drug Therapy, Combination; Female; | 1986 |
The future of leprosy in the Dominican Republic: experience with multidrug therapy.
Topics: Adolescent; Child; Child, Preschool; Clofazimine; Dapsone; Dominican Republic; Drug Therapy, Combina | 1986 |
Preliminary results of treatment of leprosy patients in The Netherlands with daily rifampicin, dapsone and clofazimine.
Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Leprosy; Netherlands; Recurrence; Rifampin | 1986 |
The Malta experience. Isoprodian-rifampicin combination treatment for leprosy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Dapsone; Drug Combinations; Drug Therapy, Combina | 1986 |
First assessment of the Malta Leprosy Eradication Project.
Topics: Dapsone; Drug Combinations; Drug Therapy, Combination; Evaluation Studies as Topic; Follow-Up Studie | 1986 |
Report of the joint leprosy-tuberculosis project in Paraguay.
Topics: Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Leprostatic Agents; Lepros | 1986 |
The impact of MDT implementation in the Tanzania National TB-Leprosy Programme.
Topics: Dapsone; Drug Combinations; Drug Therapy, Combination; Female; Humans; Isoniazid; Isonicotinic Acids | 1986 |
Effect of clofazimine and dapsone on rifampicin (Lositril) pharmacokinetics in multibacillary and paucibacillary leprosy cases.
Topics: Adolescent; Adult; Clofazimine; Dapsone; Drug Therapy, Combination; Humans; Kinetics; Leprosy; Male; | 1986 |
Experience with multidrug therapy in Sierra Leone: clinical, operational and managerial analysis.
Topics: Dapsone; Drug Therapy, Combination; Follow-Up Studies; Humans; Leprostatic Agents; Leprosy; Sierra L | 1986 |
Leprosy control by a people's program: "a new concept in technology transfer".
Topics: China; Community Health Workers; Dapsone; Health Policy; Humans; Leprosy; Patient Compliance; World | 1987 |
Diabetogenic effect of dapsone.
Topics: Dapsone; Diabetes Mellitus; Female; Humans; Leprosy; Male | 1987 |
Problems encountered in treating one leprosy patient in a developing country: a case report.
Topics: Adult; Dapsone; Developing Countries; Follow-Up Studies; Humans; Leprosy; Male; Thailand | 1987 |
A computer simulation of the effect of multidrug therapy on the incidence of leprosy.
Topics: Computer Simulation; Dapsone; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy; Models | 1987 |
Association between regularity in dapsone (DDS) treatment and development of deformity.
Topics: Adolescent; Adult; Age Factors; Analysis of Variance; Dapsone; Drug Administration Schedule; Female; | 1987 |
Feasibility of multidrug therapy (MDT) in Hansen's disease in an urban population--Curupaiti State Hospital, Rio de Janeiro, Brazil.
Topics: Adolescent; Adult; Brazil; Clofazimine; Dapsone; Drug Therapy, Combination; Ethionamide; Female; Hum | 1987 |
Method for detecting sulfones in urine.
Topics: Dapsone; Humans; Leprosy; Patient Compliance | 1987 |
Short-course multidrug therapy for leprosy patients in western Kenya. Preliminary communication.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Dapsone; Drug Administration Schedule; Drug Thera | 1987 |
Effective prophylactic measures against accidental inoculation with live Mycobacterium leprae in laboratory and hospital workers.
Topics: Accidents, Occupational; Dapsone; Humans; Laboratories; Leprosy; Personnel, Hospital; Punctures; Rif | 1987 |
Multidrug therapy for paucibacillary leprosy: WHO regimen inadequate?
Topics: Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leprosy; Rifampin; World H | 1987 |
The effect of dapsone in high and normal dosage on the clinical and cell-mediated immune status of patients with borderline (BT-BL) leprosy.
Topics: Dapsone; Drug Administration Schedule; Humans; Immunity, Cellular; Leprosy; Random Allocation | 1986 |
A study of drug interactions in leprosy--1. Effect of simultaneous administration of prothionamide on metabolic disposition of rifampicin and dapsone.
Topics: Dapsone; Drug Interactions; Humans; Isonicotinic Acids; Kinetics; Leprosy; Prothionamide; Rifampin | 1986 |
Dapsone syndrome occurring in two brothers.
Topics: Adult; Dapsone; Drug Hypersensitivity; Humans; Leprosy; Male; Syndrome | 1986 |
Oily injections of dapsone; an acceptable form of treatment?
Topics: Adolescent; Adult; Dapsone; Female; Humans; Injections, Intramuscular; Leprosy; Male; Middle Aged; S | 1986 |
Spot test for detection of dapsone in urine: an assessment of its validity and interpretation in monitoring dapsone self-administration.
Topics: Dapsone; Female; Humans; Leprosy; Male; Patient Compliance; Self Administration | 1986 |
Prospective study on the relationship between intensive bactericidal therapy and leprosy reactions.
Topics: Adult; Child; Clofazimine; Dapsone; Drug Therapy, Combination; Edema; Erythema Nodosum; Ethionamide; | 1986 |
Electrogustometry in Hansen's disease (study of 225 cases).
Topics: Adolescent; Adult; Ageusia; Clofazimine; Dapsone; Erythema Nodosum; Facial Paralysis; Female; Humans | 1986 |
Acute renal failure--a complication of new multidrug regimen for treatment of leprosy.
Topics: Acute Kidney Injury; Adult; Dapsone; Drug Hypersensitivity; Drug Therapy, Combination; Humans; Lepro | 1986 |
The rate of relapse in lepromatous leprosy following completion of twenty years of supervised sulphone therapy.
Topics: Dapsone; Female; Humans; Leprosy; Male; Recurrence; Sulfones | 1986 |
Implementation of multidrug therapy in the ALERT Leprosy Programme in the Shoa Region of Ethiopia. First results with paucibacillary patients.
Topics: Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Ethiopia; Humans; Leprosy; Rifampi | 1986 |
Monitoring dapsone self-administration in a multidrug therapy programme.
Topics: Adolescent; Adult; Clofazimine; Dapsone; Drug Therapy, Combination; Ethiopia; Female; Humans; Lepros | 1986 |
[Combination chemotherapy in leprosy].
Topics: Clofazimine; Dapsone; Drug Administration Schedule; Drug Therapy, Combination; Humans; Leprostatic A | 1986 |
Ten years' leprosy control work in Malaŵi (Central Africa)--I. Methods and outcome after treatment.
Topics: Dapsone; Female; Humans; Leprosy; Malawi; Male | 1986 |
[Pathomorphology of leprosy].
Topics: Dapsone; Diagnosis, Differential; Humans; Immunity, Cellular; Leprosy; Microscopy, Electron; Nerve D | 1986 |
The effect of clofazimine on the pharmacokinetics of rifampicin and dapsone in leprosy.
Topics: Clofazimine; Dapsone; Half-Life; Humans; Kinetics; Leprosy; Rifampin | 1986 |
Evaluation of a continual compliance monitoring program for dapsone in an outpatient Hansen's disease clinic.
Topics: Ambulatory Care Facilities; Creatine; Dapsone; Female; Humans; Leprosy; Male; Monitoring, Physiologi | 1986 |
Radio diagnosis of skin disease.
Topics: Adult; Dapsone; Female; Humans; Leprosy; Patient Education as Topic; Physician-Patient Relations; Ra | 1987 |
Immunostimulation with an allied mycobacterium and DDS chemotherapy in lepromatous leprosy.
Topics: Combined Modality Therapy; Dapsone; Humans; Immunization; Leprosy; Mycobacterium | 1985 |
Leprosy and the eye: a review.
Topics: Bacterial Vaccines; Clofazimine; Dapsone; Drug Therapy, Combination; Eye Diseases; Humans; Leprosy; | 1985 |
DDS-resistant leprosy.
Topics: Animals; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mice; Mycobacterium leprae | 1985 |
Drug sensitivity testing of M. leprae.
Topics: Dapsone; Humans; Leprosy; Microbial Sensitivity Tests; Mycobacterium leprae | 1985 |
Detection of phenolic glycolipid I in sera from patients with lepromatous leprosy.
Topics: Antibodies, Bacterial; Antigens, Bacterial; Dapsone; Glycolipids; Humans; Leprosy; Mycobacterium lep | 1985 |
Recent trends in chemotherapy of leprosy.
Topics: Clofazimine; Dapsone; Drug Combinations; Drug Therapy, Combination; Humans; Isoniazid; Leprostatic A | 1985 |
The Kellersberger memorial lecture, 1984. Chemotherapy of leprosy--a tool for leprosy control.
Topics: Dapsone; Drug Therapy, Combination; Ethiopia; Humans; Leprostatic Agents; Leprosy; Recurrence | 1985 |
Risk of paucibacillary leprosy patients released from control relapsing with multibacillary leprosy.
Topics: Dapsone; Humans; Lepromin; Leprosy; Recurrence; Risk | 1985 |
Absence from sera from normal individuals or from rifampin-treated leprosy patients (THELEP trials) of antibody to rifamycin-protein or rifamycin-membrane conjugates.
Topics: Animals; Antibodies, Bacterial; Clofazimine; Coombs Test; Dapsone; Drug Therapy, Combination; Enzyme | 1985 |
Leprosy control in Shandong Province, China, 1955-1983; some epidemiological features.
Topics: Adolescent; Adult; Age Factors; China; Dapsone; Drug Administration Schedule; Female; Humans; Lepros | 1985 |
Hypercalcemia in leprosy.
Topics: Arthritis, Rheumatoid; Calcitonin; Calcium; Dapsone; Female; Humans; Hypercalcemia; Leprosy; Middle | 1985 |
Effect of levamisole on bacterial index in BL and LL leprosy.
Topics: Adult; Dapsone; Female; Humans; Leprosy; Levamisole; Male | 1985 |
Muramidase (lysozyme) findings in sural and radial nerve biopsies in leprosy patients after varying periods of treatment.
Topics: Adolescent; Adult; Dapsone; Female; Humans; Leprosy; Male; Middle Aged; Muramidase; Radial Nerve; Su | 1985 |
Standardized schemes for steroid treatment in ENL and reversal reactions.
Topics: Adrenal Cortex Hormones; Dapsone; Erythema Nodosum; Humans; Leprosy; Prednisone | 1985 |
The outpatient treatment of nerve damage in patients with borderline leprosy using a semi-standardized steroid regimen.
Topics: Ambulatory Care; Dapsone; Humans; Leprosy; Neuritis; Patient Education as Topic; Prednisolone | 1985 |
Managerial implications of multidrug therapy.
Topics: Costs and Cost Analysis; Dapsone; Drug Therapy, Combination; Humans; Leprostatic Agents; Leprosy; Pr | 1985 |
Polytherapy in multibacillary leprosy patients in Nepal.
Topics: Clofazimine; Dapsone; Drug Therapy, Combination; Female; Humans; Leprostatic Agents; Leprosy; Male; | 1985 |
Dapsone resistant leprosy, the western Kenya experience.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Kenya; Leprosy | 1985 |
Leprosy in children aged 0-14 years: report of an 11-year control programme.
Topics: Adolescent; Age Factors; Child; Child, Preschool; Dapsone; Ethnicity; Humans; Infant; Infant, Newbor | 1985 |
Dapsone is safe during pregnancy.
Topics: Dapsone; Female; Fetus; Humans; Leprosy; Pregnancy; Pregnancy Complications, Infectious | 1985 |
Chromosomal aberrations in cultures of skin fibroblasts of leprosy patients.
Topics: Adolescent; Adult; Aged; Aneuploidy; Biopsy; Chromatids; Chromosome Aberrations; Dapsone; Diploidy; | 1985 |
Antileprosy drugs.
Topics: Anemia, Hemolytic; Aniline Compounds; Anti-Bacterial Agents; Dapsone; Drug Resistance, Microbial; Hu | 1971 |
Repository acedapsone in leprosy chemoprophylaxis and treatment.
Topics: Administration, Oral; Adolescent; Adult; Aged; Child; Dapsone; Delayed-Action Preparations; Drug Tol | 1971 |
Prevention of leprosy.
Topics: Animals; BCG Vaccine; Dapsone; Humans; Injections, Intramuscular; Leprosy; Mice; Mycobacterium lepra | 1971 |
Prevention of leprosy.
Topics: Administration, Oral; Dapsone; Humans; Injections; Leprosy | 1971 |
Prevention of leprosy.
Topics: Dapsone; Humans; Leprosy | 1971 |
Prevention of leprosy.
Topics: Africa; BCG Vaccine; Dapsone; Humans; India; Leprosy | 1972 |
The treatment of leprosy and its acute complications.
Topics: Aniline Compounds; Anti-Bacterial Agents; Dapsone; Epistaxis; Eye Manifestations; Humans; Imines; Le | 1973 |
The relationship of the P-K titre to the serum IgE level in patients with leprosy.
Topics: Animals; Antigens; Codeine; Dapsone; Guinea Pigs; Histamine; Histamine Release; Humans; Immunoglobul | 1974 |
Current leprosy research: a report on the 10th Internation Leprosy Congress.
Topics: Animals; Congresses as Topic; Dapsone; Humans; Leprosy; Mycobacterium lepraemurium; Norway; Research | 1974 |
Leprosy undefeated.
Topics: Dapsone; Humans; Leprosy | 1965 |
Morphology of Mycobacterium leprae in tissue sections.
Topics: Adult; Antithyroid Agents; Biopsy; Dapsone; Drug Resistance, Microbial; Female; Goiter; Humans; Lepr | 1967 |
Morphology of Mycobacterium leprae in tissue sections. Correlation with results of mouse foot pad inoculation.
Topics: Animals; Culture Techniques; Dapsone; Humans; Leprosy; Mice; Mycobacterium leprae; Staining and Labe | 1969 |
[Chemotherapy of leprosy].
Topics: Dapsone; Female; Humans; Isoniazid; Leprosy; Male; Sulfadiazine; Sulfones; Thioacetazone; Urea; Vita | 1970 |
[A case of leprous nodular episcleritis]?1.
Topics: Adult; Chloramphenicol; Dapsone; Eye Diseases; Follow-Up Studies; Humans; Leprosy; Male; Prednisone; | 1974 |
Calcification of superficial nerves in leprosy.
Topics: Calcinosis; Dapsone; Humans; Leprosy; Peripheral Nervous System Diseases | 1967 |
Leprosy.
Topics: Acute Disease; Dapsone; Diagnosis, Differential; Humans; Leprosy; Peripheral Nervous System Diseases | 1968 |
A case of leprous nodular interstitial myositis.
Topics: Adrenocorticotropic Hormone; Adult; Dapsone; Edema; Erythema; Humans; Ichthyosis; Leprosy; Male; Myo | 1972 |
Leprosy in Ceylon.
Topics: Adolescent; Adult; Child; Child, Preschool; Dapsone; Female; Humans; Leprosy; Male; Skin Ulcer; Soci | 1970 |
Kinetic testing of drugs against Mycobacterium leprae in mice. Activity of cephaloridine, rifampin, streptovaricin, vadrine, and viomycin.
Topics: Animals; Antimalarials; Cephaloridine; Dapsone; Diet; Evaluation Studies as Topic; Injections, Subcu | 1971 |
Do leprosy patients take dapsone regularly?
Topics: Cooperative Behavior; Creatinine; Dapsone; Dose-Response Relationship, Drug; Humans; Leprosy; Self M | 1974 |
The application of urine tests to monitor the regularity of dapsone self-administration.
Topics: Colorimetry; Cooperative Behavior; Creatinine; Dapsone; Fluorometry; Humans; Leprosy; Self Medicatio | 1974 |
Editorial: Problems and opportunities in the therapy of leprosy.
Topics: Clofazimine; Dapsone; Drug Resistance, Microbial; Humans; Leprostatic Agents; Leprosy; Rifampin | 1974 |
The pharmacology of sulphetrone and its implications in sulphone resistance.
Topics: Dapsone; Drug Resistance, Microbial; Female; Humans; Leprosy; Male; Spectrometry, Fluorescence; Sulf | 1974 |
Thymus-dependent lymphocytes of peripheral blood in leprosy patients.
Topics: Adult; Aged; Animals; Blood Cell Count; Clofazimine; Dapsone; Erythema Nodosum; Erythrocytes; Humans | 1974 |
Factors influencing the level of dapsone in blood.
Topics: Adult; Dapsone; Humans; Leprosy; Male; Middle Aged | 1974 |
Prolongation of the lag phase of Mycobacterium leprae by dapsone.
Topics: Animals; Cell Division; Dapsone; Leprosy; Male; Mice; Mice, Inbred Strains; Mycobacterium leprae; Ti | 1972 |
Clofazimine therapy of lepromatous leprosy caused by dapsone-resistant mycobacterium leprae.
Topics: Administration, Oral; Adult; Aged; Aniline Compounds; Animals; Biopsy; Dapsone; Drug Resistance, Mic | 1972 |
[Chemotherapy of leprosy--effect of the anti-leprotic agent on the growth of acid-fast bacilli in cutaneous and mucous tissue].
Topics: Adult; Age Factors; Aged; Aniline Compounds; Dapsone; Female; Humans; Leprosy; Male; Middle Aged; My | 1972 |
The effect of rifampicin and dapsone on experimental Mycobacterium leprae infections: minimum inhibitory concentrations and bactericidal action.
Topics: Administration, Oral; Animal Feed; Animals; Dapsone; Drug Resistance, Microbial; Kinetics; Leprosy; | 1972 |
The continuous bacteremia of lepromatous leprosy.
Topics: Biopsy; Dapsone; Histiocytes; Humans; Leprosy; Leukocytes; Liver; Monocytes; Mycobacterium leprae; S | 1972 |
The death rate of Mycobacterium leprae during treatment of lepromatous leprosy with acedapsone (DADDS).
Topics: Animals; Biopsy; Dapsone; Humans; Leprosy; Mice; Mycobacterium leprae; Rifampin; Skin | 1972 |
Rapid bactericidal effect of rifampin on Mycobacterium leprae.
Topics: Animals; Biopsy; Dapsone; Humans; Leprosy; Mice; Mycobacterium leprae; Rifampin; Skin | 1972 |
Dapsone acetylation and the treatment of leprosy.
Topics: Acetates; Dapsone; Humans; Isoniazid; Leprosy | 1972 |
DDS: mechanisms of action and structure-activity relationships.
Topics: Adenosine; Animals; Biological Transport; Cell Membrane Permeability; Dapsone; Leprosy; Malaria; Pla | 1972 |
B lymphocytes in lepromatous leprosy.
Topics: Adult; Aged; B-Lymphocytes; Dapsone; Fluorescent Antibody Technique; Humans; Immune Sera; Immunoglob | 1973 |
Correlation of laboratory and clinical data during treatment of leprosy.
Topics: Aniline Compounds; Animals; Antimalarials; Dapsone; Drug Resistance, Microbial; Humans; Imines; Lepr | 1972 |
Acute adenopathy in a young man.
Topics: Adult; Animals; Dapsone; Diagnosis, Differential; Erythema Nodosum; Granuloma; Guinea Pigs; Humans; | 1973 |
The effect of antibacterial drugs on the ultrastructure of Mycobacterium leprae in human skin.
Topics: Anti-Bacterial Agents; Dapsone; Humans; Leprosy; Microscopy, Electron; Mycobacterium leprae; Rifampi | 1972 |
Ulcerating lepromatous leprosy in a patient with dapsone-resistant Mycobacterium leprae.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Male; Middle Aged; Mycobacterium leprae; Rifam | 1973 |
Potential antileprotic agents. 1. Inhibition of a model mycobacterial system by diaryl sulfones.
Topics: Animals; Biological Transport, Active; Dapsone; Drug Resistance, Microbial; Leprosy; Mice; Microbial | 1974 |
Evidence that the mechanism of immunological tolerance ("central failure") is operative in the lack of host resistance in lepromatous leprosy.
Topics: Adult; Cell Migration Inhibition; Dapsone; Humans; Immune Tolerance; Immunity, Cellular; Leprosy; Le | 1972 |
Fundamental data, methods and goals of present research on the treatment of leprosy.
Topics: Animals; Animals, Laboratory; Antitubercular Agents; Clofazimine; Dapsone; Ethionamide; Humans; In V | 1973 |
[Initial clinical results using new, experimentally developed therapeutic forms in leprosy].
Topics: Adolescent; Adult; Aged; Antitubercular Agents; Child; Dapsone; Drug Therapy, Combination; Ethiopia; | 1973 |
Editorial: Prevention of leprosy.
Topics: Animals; Bacteriological Techniques; Body Temperature; Child; Dapsone; Disease Models, Animal; Human | 1974 |
Trophic skin ulceration of leprosy: skin and serum zinc concentrations.
Topics: Biopsy; Dapsone; Dermatitis Herpetiformis; Humans; Keratins; Leprosy; Mycobacterium leprae; Protein | 1974 |
Dapsone resistance in leprosy.
Topics: Animals; Clofazimine; Dapsone; Drug Resistance, Microbial; Leprosy; Mice; Mycobacterium leprae; Rifa | 1973 |
Viability of blood-borne Mycobacterium leprae.
Topics: Adult; Aged; Animals; Dapsone; Female; Humans; Leprosy; Male; Mice; Middle Aged; Mycobacterium lepra | 1974 |
Drug resistance in leprosy.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mycobacterium leprae; Sulfones | 1974 |
Ten years of dapsone in lepromatous leprosy: clinical, bacteriological and histological assessment and the finding of viable leprosy bacilli.
Topics: Adolescent; Adult; Aged; Biopsy; Dapsone; Drug Evaluation; Follow-Up Studies; Humans; Leprosy; Male; | 1974 |
Pathologic changes in the soft palate in lepromatous leprosy. An evaluation of ten patients.
Topics: Adolescent; Adult; Aged; Dapsone; Deglutition; Female; Humans; Leprosy; Male; Middle Aged; Mouth Dis | 1974 |
Letter: An acute attack of quartan malaria in a leprosy patient being treated with diaminodiphenylsulphone.
Topics: Acute Disease; Adult; Dapsone; Humans; Leprosy; Malaria; Malaysia; Male; Plasmodium malariae | 1974 |
Influence of chemotherapy and serum factors on the mitogenic response of peripheral leucocytes of leprosy patients to phytohaemagglutinin.
Topics: Adolescent; Adult; Dapsone; DNA; Female; Humans; Lectins; Leprosy; Leukocytes; Lymphocyte Activation | 1972 |
Copper in leprosy blood plasma concentration and urinary excretion.
Topics: Ceruloplasmin; Copper; Dapsone; Female; Humans; Leprosy; Male | 1972 |
Haemolytic effects of DDS in leprosy patients.
Topics: Adult; Anemia, Hemolytic; Dapsone; Erythrocytes; Female; Glucosephosphate Dehydrogenase Deficiency; | 1972 |
A new analogous model for the detection and evaluation of chemotherapeutic products effective in leprosy.
Topics: Aniline Compounds; Animals; Dapsone; Disease Models, Animal; Drug Combinations; Ethionamide; Humans; | 1972 |
Renal manifestations of leprosy: impaired acidification and concentration of urine in patients with leprosy.
Topics: Adult; Dapsone; Female; Humans; Hydrogen-Ion Concentration; Kidney Concentrating Ability; Kidney Tub | 1973 |
Drugs for leprosy.
Topics: Adult; Animals; Biopharmaceutics; Dapsone; Humans; Leprosy; Mice; Phenazines; Rifampin; Thiourea | 1973 |
Lepromatous leprosy.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Male; Middle Aged; Rifampin | 1973 |
Dapsone toxicity.
Topics: Adult; Dapsone; Female; Humans; Leprosy; Psychoses, Substance-Induced | 1973 |
The effect of stopping dapsone treatment for two months and then restarting it in full dosage in patients with moderately severe erythema nodosum leprosum.
Topics: Dapsone; Erythema Nodosum; Humans; Leprosy; Placebos | 1973 |
Leprosy--a complementary contribution.
Topics: Animals; Anti-Infective Agents; BCG Vaccine; Crowding; Dapsone; Disease Reservoirs; Disease Vectors; | 1973 |
Dapsone-resistant leprosy.
Topics: Dapsone; Drug Resistance, Microbial; Female; Humans; Leprosy; Middle Aged | 1973 |
Gas chromatographic methods for analysis of sulfone drugs used in leprosy chemotherapy.
Topics: Acetamides; Aniline Compounds; Animals; Chromatography, Gas; Dapsone; Humans; Leprosy; Mammals; Meth | 1973 |
A note on atypical serum cholinesterase and genetic factors in leprosy.
Topics: Cholinesterase Inhibitors; Cholinesterases; Dapsone; Dibucaine; Ethiopia; Genetic Variation; Humans; | 1973 |
[Scandinavian leprosy conference in Bergen. What do we know about leprosy and what do we do about it?].
Topics: Dapsone; Ethiopia; Humans; International Cooperation; Leprosy; Male; Scandinavian and Nordic Countri | 1973 |
[Administration of a new antimycobacterial combined therapy in leprosy in East Africa].
Topics: Africa, Eastern; Antitubercular Agents; Dapsone; Drug Therapy, Combination; Female; Humans; Isoniazi | 1973 |
Treatment of leprosy.
Topics: Dapsone; Drug Resistance, Microbial; Humans; Leprosy | 1973 |
Acedapsone in the preventive treatment of leprosy.
Topics: Adult; Child; Child, Preschool; Dapsone; Humans; Infant; Injections, Intramuscular; Leprosy; Male; M | 1973 |
Metabolic disposition of dapsone in patients with dapsone-resistant leprosy.
Topics: Acylation; Adult; Aged; Dapsone; Drug Resistance, Microbial; Female; Humans; Leprosy; Male; Middle A | 1974 |
Urine tests to monitor the self-administration of dapsone by leprosy patients.
Topics: Colorimetry; Creatinine; Dapsone; Filtration; Humans; Indicators and Reagents; Leprosy; Methods | 1974 |
Clinical correlates of C1Q-precipitating substances in the sera of patients with leprosy.
Topics: Complement System Proteins; Cryoglobulins; Dapsone; Humans; Leprosy; Precipitin Tests; Precipitins; | 1974 |
Dapsone in leprosy.
Topics: Dapsone; Dose-Response Relationship, Drug; Drug Resistance; Humans; Leprosy; Time Factors | 1974 |
The clinical evaluation of drugs for leprosy.
Topics: Dapsone; Humans; Leprosy; Mycobacterium leprae; Phenazines; Sulfonamides | 1967 |
[On the diagnosis and differential diagnosis of individual leprosy cases based on 5 cases observed in Zurich].
Topics: Adult; Aged; Dapsone; Diagnosis, Differential; Humans; Leprosy; Male; Mycobacterium leprae; Switzerl | 1967 |
The death of Mycobacterium leprae during treatment with 4,4'-diaminodiphenylsulfone (DDS). Initial rate in patients.
Topics: Animals; Biopsy; Dapsone; Humans; Leprosy; Mice; Mycobacterium leprae; Nasal Mucosa; Skin | 1968 |
The sensitivity to Dapsone (DDS) of Mycobacterium leprae from patients with and without previous treatment.
Topics: Animals; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Mice; Mycobacterium leprae; Sulfones | 1969 |
Transmission of human leprosy to the mouse and its clinical implications.
Topics: Animals; Communicable Diseases; Dapsone; Disease Models, Animal; Drug Resistance, Microbial; Hindlim | 1970 |
Application of spectrophotofluorometric procedures to some problems in Mycobacterium leprae infections in mice and man treated with dapsone (DDS), diacetyl-DDS (DADDS), and di-formyl-DDS (DFD).
Topics: Acetates; Animals; Colorimetry; Dapsone; Disease Models, Animal; Fluorometry; Formates; Half-Life; H | 1971 |
The minimal inhibitory concentrations of sulphadimethozine and sulphadoxine against Mycobacterium leprae.
Topics: Animals; Dapsone; Leprosy; Male; Mice; Mycobacterium leprae; Pyrimidines; Sulfadimethoxine; Sulfonam | 1970 |
A preliminary report on the use of the depot sulphone preparation acedapsone ("Hansolar") in the control of leprosy.
Topics: Dapsone; Delayed-Action Preparations; Drug Resistance, Microbial; Humans; Injections, Intramuscular; | 1971 |
[localization and topographic distribution of Hansen's bacilli at the level of leprotic lesions].
Topics: Biopsy; Dapsone; Humans; Leprosy; Mycobacterium leprae | 1971 |
WHO expert committee on leprosy.
Topics: Attitude to Health; BCG Vaccine; Dapsone; Disability Evaluation; Disease Models, Animal; Health Educ | 1970 |
Dapsone induced psychosis--a case report.
Topics: Adult; Dapsone; Humans; Leprosy; Male; Psychoses, Substance-Induced | 1972 |
Why agranulocytosis from dapsone?
Topics: Agranulocytosis; Dapsone; Humans; Leprosy; Military Medicine; United States; Vietnam | 1972 |
Clofazimine (B663, Geigy) in leprosy reactions.
Topics: Adult; Aniline Compounds; Anti-Infective Agents; Dapsone; Female; Humans; Imines; Leprosy; Male; Phe | 1972 |
A chromatographic-fluorometric procedure for the determination of nanogram quantities of antileprotic sulfones.
Topics: Chromatography; Dapsone; Fluorometry; Humans; Indicators and Reagents; Leprosy; Methods; Microchemis | 1971 |
Diamino diphenyl sulfone in leprosy chemoprophylaxis.
Topics: Adolescent; Anemia; Child; Child, Preschool; Dapsone; Evaluation Studies as Topic; Humans; Infant; L | 1971 |
Antileprosy drugs.
Topics: Dapsone; Humans; Leprosy; Psychoses, Substance-Induced | 1971 |
Antileprosy drugs.
Topics: Dapsone; Delusions; Hallucinations; Humans; Leprosy; Psychoses, Substance-Induced; Schizophrenia; Sl | 1971 |
Trial of high dosages of dapsone in the treatment of tuberculoid leprosy.
Topics: Dapsone; Female; Headache; Humans; Leprosy; Male | 1971 |
Four years' experience with dapsone as prophylaxis against leprosy.
Topics: Child; Dapsone; Humans; Leprosy; Uganda | 1971 |
Lamprene: first results of treatment in the Netherlands in a group of 6 leprosy patients.
Topics: Adult; Aged; Aniline Compounds; Dapsone; Drug Combinations; Female; Humans; Leprosy; Male; Middle Ag | 1971 |
Forty-four months' experience in the treatment of leprosy with clofazimine (Lamprene (Geigy)).
Topics: Dapsone; Drug Resistance, Microbial; Erythema Nodosum; Female; Humans; Leprosy; Neuritis; Phenazines | 1971 |
Exacerbation of dimorphous leprosy apparently due to BCG vaccination.
Topics: Adult; BCG Vaccine; Dapsone; Female; Humans; Leprosy | 1971 |
Preliminary test using DMSO as a vehicle for drugs in leprosy.
Topics: Aminosalicylic Acids; Dapsone; Dimethyl Sulfoxide; Humans; Isoniazid; Leprosy; Pharmaceutical Vehicl | 1967 |
Dapsone acetylation in man: another example of polymorphic acetylation.
Topics: Acetates; Acylation; Adult; Blood Proteins; Dapsone; Female; Fluorometry; Genetics, Medical; Half-Li | 1971 |
Progress in leprosy research.
Topics: Animals; Dapsone; Leprosy; Mice; Mycobacterium leprae | 1966 |
Dapsone-resistant lepromatous leprosy in England.
Topics: Adult; Dapsone; Drug Resistance, Microbial; England; Humans; Leprosy; Male; Mycobacterium leprae | 1966 |
Sensitivity of Mycobacterium leprae to low levels of 4,4'-diaminodiphenyl sulfone.
Topics: Animals; Dapsone; Humans; Leprosy; Mice; Mycobacterium leprae | 1966 |
Activity of repository sulfones against Mycobacterium leprae in mice.
Topics: Animals; Dapsone; Drug Resistance, Microbial; Leprosy; Mice; Mycobacterium leprae; Sulfones; Triazin | 1967 |
Lepromatous leprosy.
Topics: Adult; Connecticut; Dapsone; Humans; Leprosy; Male; Puerto Rico | 1969 |
The effect of out-patient dapsone in an area of endemic leprosy.
Topics: Dapsone; Humans; Leprosy; Nigeria; Outpatient Clinics, Hospital | 1969 |
[Report on the Boerhaave course "leprosy" on September 9, 1968 in Leiden, The Netherlands].
Topics: Dapsone; Humans; Indonesia; Leprosy; Netherlands | 1969 |
A plan of leprosy control in Nepal being carried out in a general hospital.
Topics: Adolescent; Adult; Child; Child, Preschool; Dapsone; Hospitals, General; Humans; Infant; Infant, New | 1969 |
"Mobile" leprosy control in the Eastern Province of Zambia. I and II.
Topics: Dapsone; Leprosy; Mobile Health Units; Zambia | 1970 |
"Mobile" leprosy control in the Eastern Province of Zambia. 3.
Topics: Dapsone; Humans; Leprosy; Mobile Health Units; Zambia | 1970 |
Ocular leprosy in Malawi. Clinical and therapeutic survey of 8,325 leprosy patients.
Topics: Adrenal Cortex Hormones; Blindness; Dapsone; Eye Diseases; Humans; Keratitis; Leprosy; Malawi; Uveit | 1970 |
Leprosy.
Topics: Dapsone; Diagnosis, Differential; Humans; Leprosy; Skin Diseases | 1970 |
[Information on a visit to India (5-17--6-18 1969)].
Topics: BCG Vaccine; Dapsone; Hospitals, Special; India; Leper Colonies; Leprosy; Sulfadimethoxine | 1970 |
Long term observation of sulphone therapy in non-lipramatous cases: study in 254 cases.
Topics: Dapsone; Humans; Leprosy | 1970 |
[. 663 (G 30320 "Geigy"), a new chemotherapeutic agent against leprosy].
Topics: Antitubercular Agents; Dapsone; Drug Resistance, Microbial; Humans; Leprosy; Phenazines | 1967 |
A new method for the manufacture of bis(4-aminophenyl) -sulfone and the anti-leprosy, anti-tuberculosis, and antibiotic activities of some new derivatives related to this drug. II.
Topics: Anhydrides; Animals; Carbon Isotopes; Cats; Cattle; Cyanates; Dapsone; Dysentery, Bacillary; Goats; | 1967 |
A new method for the manufacture of bis(4-aminophenyl)-sulfone and the anti-leprosy, anti-tuberculosis, and antibiotic activities of some new derivatives related to the drug. I.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Ascorbic Acid; Bacteria; Cholera; Dapsone; Dysentery, | 1967 |
Urinary excretory pattern of DDS in leprosy patients.
Topics: Adolescent; Adult; Aged; Child; Dapsone; Drug Resistance, Microbial; Female; Humans; Leprosy; Male; | 1968 |
An outbreak of leprosy in a previously unexposed population of eastern New Guinea.
Topics: Adolescent; Adult; Age Factors; Carrier State; Child; Child, Preschool; Dapsone; Disease Outbreaks; | 1968 |
[Biological anti-oxidant activity of diaminodiphenylsulfone (D.D.S.)].
Topics: Adipose Tissue; Aniline Compounds; Animals; Dapsone; Growth; Humans; Leprosy; Male; Oxidation-Reduct | 1968 |
New drug for leprosy.
Topics: Animals; Dapsone; Humans; Leprosy; Mice; Phenazines | 1969 |
An open trial of low doses of dapsone in the management of lepromatous leprosy.
Topics: Dapsone; Humans; Leprosy; Skin | 1969 |
The management of leprosy and its complications.
Topics: Amyloidosis; Dapsone; Erythema Nodosum; Humans; Leprosy; Neuritis; Tuberculosis | 1965 |
Six years follow-up of diphenylthiourea treatment.
Topics: Dapsone; Follow-Up Studies; Humans; Leprosy; Thiourea | 1965 |
Chemoprophylaxis with DDS, mainly in children: a short trial.
Topics: Child, Preschool; Dapsone; Humans; Infant; Leprosy | 1965 |
Bacterial clearance in patients with lepromatous leprosy not receiving treatment.
Topics: Adult; Dapsone; Female; Humans; Leprosy; Psychoses, Substance-Induced | 1965 |
Low dosage of DDS.
Topics: Dapsone; Humans; Leprosy; Nigeria; Statistics as Topic | 1966 |
Absorption, metabolism and excretion of di(rho-aminophenyl) sulphone (dapsone) and di(rho-aminophenyl) sulphoxide in man.
Topics: Dapsone; Humans; Leprosy; Sulfoxides | 1966 |
Lepra insidiosa.
Topics: Adult; Blood Sedimentation; Carrier State; Climate; Dapsone; Follow-Up Studies; Humans; Leprosy; Mal | 1966 |
Clinical evaluation of the dosage of D.D.S.
Topics: Dapsone; Female; Humans; Leprosy; Male | 1966 |
Chemoprophylaxis of leprosy contacts with D.D.S.
Topics: Adolescent; Child; Dapsone; Humans; Leprosy | 1966 |