Page last updated: 2024-10-25

dapsone and Disease Models, Animal

dapsone has been researched along with Disease Models, Animal in 56 studies

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"We evaluate the effect of dapsone on tactile allodynia and mechanical hyperalgesia and to determine its anti-oxidant effect in a spinal cord injury (SC) model in rats."8.02Dapsone Prevents Allodynia and Hyperalgesia and Decreased Oxidative Stress After Spinal Cord Injury in Rats. ( Burelo, M; Calderón-Estrella, F; Camilo, R; Diaz-Ruiz, A; García-Martínez, BA; Jardon-Guadarrama, G; Mata-Bermudez, A; Pérez-González, C; Rangel-Hernández, A, 2021)
"In this study, colitis was induced by instillation of 2,4,6-trinitrobenzenesulfonic acid (TNBS) 100 mg/kg."8.02Dapsone Ameliorates Colitis through TLR4/NF-kB Pathway in TNBS Induced Colitis Model in Rat. ( Ala, M; Dehpour, AR; Hashemian, SM; Mohammad Jafari, R; Rashidian, A; Shayesteh, S; Sorouri, M; Yousefi-Manesh, H, 2021)
"Dapsone is a sulfone chemical with reported anti-inflammatory and antibacterial properties."5.72The anti-inflammatory effect of dapsone on ovalbumin-induced allergic rhinitis in balb/c mice. ( Alaeddini, M; Dabiri, S; Dehpour, AR; Etemad-Moghadam, S; Fatehi-Zardalou, M; Hemmati, S; Madanipour, MR; Rahimi, N; Shayan, M, 2022)
"To investigate this, we created a hemorrhagic shock model rat, followed by resuscitation with RBC and CO-RBC."5.40Carbon monoxide-bound red blood cell resuscitation ameliorates hepatic injury induced by massive hemorrhage and red blood cell resuscitation via hepatic cytochrome P450 protection in hemorrhagic shock rats. ( Ishima, Y; Maruyama, T; Ogaki, S; Otagiri, M; Taguchi, K; Watanabe, H, 2014)
"Dapsone has been shown to possess anti-inflammatory activity in a variety of animal models."5.26The anti-inflammatory profile of dapsone in animal models of inflammation. ( Gemmell, DK; Lewis, AJ; Stimson, WH, 1978)
"We evaluate the effect of dapsone on tactile allodynia and mechanical hyperalgesia and to determine its anti-oxidant effect in a spinal cord injury (SC) model in rats."4.02Dapsone Prevents Allodynia and Hyperalgesia and Decreased Oxidative Stress After Spinal Cord Injury in Rats. ( Burelo, M; Calderón-Estrella, F; Camilo, R; Diaz-Ruiz, A; García-Martínez, BA; Jardon-Guadarrama, G; Mata-Bermudez, A; Pérez-González, C; Rangel-Hernández, A, 2021)
"In this study, colitis was induced by instillation of 2,4,6-trinitrobenzenesulfonic acid (TNBS) 100 mg/kg."4.02Dapsone Ameliorates Colitis through TLR4/NF-kB Pathway in TNBS Induced Colitis Model in Rat. ( Ala, M; Dehpour, AR; Hashemian, SM; Mohammad Jafari, R; Rashidian, A; Shayesteh, S; Sorouri, M; Yousefi-Manesh, H, 2021)
"5-(2-Pyridylsulfonyl)-2-thiazolamine (2) was effective both in mitomycin C (MMC)-induced thrombocytopenia and in an animal model of idiopathic thrombocytopenic purpura (ITP)."3.70Synthesis and effects of novel thiazole derivatives against thrombocytopenia. ( Manda, T; Matsuo, M; Nishigaki, F; Ogino, T; Sawada, M; Seki, N; Sudo, Y; Tsuji, K, 1998)
"Dapsone (DAP) is a long-established molecule that remains a promising therapeutic agent for various diseases mainly because it combines antimicrobial and anti-inflammatory activities."2.66Emerging Technologies to Target Drug Delivery to the Skin - the Role of Crystals and Carrier-Based Systems in the Case Study of Dapsone. ( Argenta, DF; Caon, T; Schneider-Rauber, G, 2020)
"Dapsone has been investigated predominantly by in vitro methods aiming to get more insights into the effect of dapsone to inflammatory effector cells, cytokines, and/or mediators, such as cellular toxic oxygen metabolism, myoloperoxidase-/halogenid system, adhesion molecules, chemotaxis, membrane-associated phospholipids, prostaglandins, leukotrienes, interleukin-8, tumor necrosis factor α, lymphocyte functions, and tumor growth."2.50Dapsone in dermatology and beyond. ( Blasum, C; Wozel, G, 2014)
"Colchicine and dapsone have been reported to be good treatment modalities when combined with corticosteroids."2.49Epidermolysis bullosa acquisita. ( Kim, JH; Kim, SC, 2013)
"DH is associated to a gluten enteropathy and its physiopathology is better known."2.47[Dermatitis herpetiformis: a review]. ( Ingen-Housz-Oro, S, 2011)
"Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial disease of the lung tissue that causes symptoms such as coughing and asthma."1.72Protective effect of dapsone against bleomycin-induced lung fibrosis in rat. ( Asgardoon, MH; Dehpour, AR; Derakhshan, MH; Noori, T; Sheibani, M; Shirooie, S; Tavangar, SM; Yousefi-Manesh, H, 2022)
"Dapsone is a sulfone chemical with reported anti-inflammatory and antibacterial properties."1.72The anti-inflammatory effect of dapsone on ovalbumin-induced allergic rhinitis in balb/c mice. ( Alaeddini, M; Dabiri, S; Dehpour, AR; Etemad-Moghadam, S; Fatehi-Zardalou, M; Hemmati, S; Madanipour, MR; Rahimi, N; Shayan, M, 2022)
"Male adult Wistar rats were subjected to middle cerebral artery occlusion (MCAO) for 90 min followed by 24 h of ischemic reperfusion (I/R)."1.56Dapsone prolong delayed excitotoxic neuronal cell death by interacting with proapoptotic/survival signaling proteins. ( Gakare, S; Kumar, R; Mahale, A; Prakash, A; Sarode, LP; Ugale, RR, 2020)
"To investigate this, we created a hemorrhagic shock model rat, followed by resuscitation with RBC and CO-RBC."1.40Carbon monoxide-bound red blood cell resuscitation ameliorates hepatic injury induced by massive hemorrhage and red blood cell resuscitation via hepatic cytochrome P450 protection in hemorrhagic shock rats. ( Ishima, Y; Maruyama, T; Ogaki, S; Otagiri, M; Taguchi, K; Watanabe, H, 2014)
"Dapsone-treated animals showed a reduction of 93% (9."1.32Neuroprotective effect of dapsone in an occlusive model of focal ischemia in rats. ( Nader-Kawachi, J; Nava-Ruiz, C; Ríos, C; Rodriguez-Payán, AJ, 2004)
"The ME7 scrapie-infected mice thus showed a characteristic complex of neurological and behavioural changes during the course of the disease that were not ameliorated by dapsone."1.31Early behavioural changes in scrapie-affected mice and the influence of dapsone. ( Deacon, RM; Guenther, K; Perry, VH; Rawlins, JN, 2001)
" Extending these experiments, we have now shown that roxithromycin at doses of 400 or 200 mg/kg/day combined with dapsone at doses of 5, 25 or 50 mg/kg/day completely prevented the development of T."1.30Experimental evaluation of roxithromycin combined with dapsone or sulphamethoxazole on Pneumocystis carinii and Toxoplasma gondii dual infections in a rat model. ( Brun-Pascaud, M; Chau, F; Derouin, F; Girard, PM, 1998)
" Ro 11-8958, TMP, and diaveridine used at a dosage of 20 mg/kg/day with SMX were only slightly more effective than SMX used alone."1.29Synergistic combinations of Ro 11-8958 and other dihydrofolate reductase inhibitors with sulfamethoxazole and dapsone for therapy of experimental pneumocystosis. ( Foy, J; Steele, P; Walzer, PD; White, M, 1993)
" carinii in vitro, a clinical trial of reduced dosage of dapsone given prophylactically to human beings is suggested."1.28Dapsone in low doses prevents Pneumocystis carinii pneumonia in the rat model. ( González-Ruiz, A; Haworth, SJ; O'Neil, AB; Warhurst, DC, 1991)
"The purpose of this study was to identify new drugs for the prevention and treatment of Pneumocystis carinii pneumonitis (PCP) induced in rats by continuous daily dosage with dexamethasone."1.27Efficacy of diaminodiphenylsulfone and other drugs in murine Pneumocystis carinii pneumonitis. ( Hughes, WT; Smith, BL, 1984)
"Suramin and dapsone were weakly active."1.27Efficacy of DL-alpha-difluoromethylornithine in a rat model of Pneumocystis carinii pneumonia. ( Clarkson, AB; Rosenberg, C; Williams, DE, 1988)
"Dapsone has been shown to possess anti-inflammatory activity in a variety of animal models."1.26The anti-inflammatory profile of dapsone in animal models of inflammation. ( Gemmell, DK; Lewis, AJ; Stimson, WH, 1978)
" Treatment with the smaller dosage of dapsone neither killed M."1.26Dapsone chemotherapy of Mycobacterium leprae infection of the neonatally thymectomized Lewis rat. ( Fieldsteel, AH; Levy, L, 1976)

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-199024 (42.86)18.7374
1990's11 (19.64)18.2507
2000's5 (8.93)29.6817
2010's7 (12.50)24.3611
2020's9 (16.07)2.80

Authors

AuthorsStudies
Ogino, T2
Tsuji, K2
Tojo, T1
Igari, N1
Seki, N2
Sudo, Y2
Manda, T2
Nishigaki, F2
Matsuo, M2
Sawada, M1
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Mata-Bermudez, A1
Diaz-Ruiz, A2
Burelo, M1
García-Martínez, BA1
Jardon-Guadarrama, G1
Calderón-Estrella, F1
Rangel-Hernández, A1
Pérez-González, C1
Camilo, R1
Yousefi-Manesh, H2
Noori, T1
Asgardoon, MH1
Derakhshan, MH1
Tavangar, SM1
Sheibani, M1
Shirooie, S1
Dehpour, AR3
Madanipour, MR1
Fatehi-Zardalou, M1
Rahimi, N1
Hemmati, S1
Alaeddini, M1
Etemad-Moghadam, S1
Shayan, M1
Dabiri, S1
Mahale, A1
Kumar, R1
Sarode, LP1
Gakare, S1
Prakash, A1
Ugale, RR1
Schneider-Rauber, G1
Argenta, DF1
Caon, T1
Moksha, L1
Halder, N1
Singh, SB1
Chawla, R1
Kumar, A1
Velpandian, T1
Mohammad Jafari, R1
Shayesteh, S1
Ala, M1
Rashidian, A1
Hashemian, SM1
Sorouri, M1
Murthy, S1
Schilf, P1
Patzelt, S1
Thieme, M1
Becker, M1
Kröger, L1
Bremer, T1
Derenda-Hell, A1
Knebel, L1
Fagiani, F1
Ibrahim, SM1
Schmidt, E1
Zillikens, D1
Sadik, CD1
Wozel, G1
Blasum, C1
Ogaki, S1
Taguchi, K1
Watanabe, H1
Ishima, Y1
Otagiri, M1
Maruyama, T1
Lee, YI1
Kang, H1
Ha, YW1
Chang, KY1
Cho, SC1
Song, SO1
Kim, H1
Jo, A1
Khang, R1
Choi, JY1
Lee, Y1
Park, SC1
Shin, JH1
Salgado-Ceballos, H1
Montes, S1
Guizar-Sahagún, G1
Gelista-Herrera, N1
Mendez-Armenta, M1
Diaz-Cintra, S1
Ríos, C2
Ingen-Housz-Oro, S1
Kanoh, S1
Tanabe, T1
Rubin, BK1
Kim, JH1
Kim, SC1
Nader-Kawachi, J1
Rodriguez-Payán, AJ1
Nava-Ruiz, C1
Marietta, E1
Black, K1
Camilleri, M1
Krause, P1
Rogers, RS1
David, C1
Pittelkow, MR1
Murray, JA1
Makarov, V1
Riabova, OB1
Yuschenko, A1
Urlyapova, N1
Daudova, A1
Zipfel, PF1
Möllmann, U1
Hughes, WT3
Smith, BL1
Moschella, SL1
Shetty, VP1
Antia, NH1
Killmar, JT1
Oz, HS1
Walzer, PD1
Foy, J1
Steele, P1
White, M1
Cole, HP1
Wesley, RE1
King, LE1
Yeo, AE1
Brun-Pascaud, M1
Chau, F1
Derouin, F1
Girard, PM1
Guenther, K1
Deacon, RM1
Perry, VH1
Rawlins, JN1
Veggi, LM1
Crocenzi, FA1
Roma, MG1
Dawson, PA1
Pellegrino, JM1
Sánchez Pozzi, EJ1
Mottino, AD1
Lewis, AJ1
Gemmell, DK1
Stimson, WH1
Loginov, VK1
Pogorelov, VN1
Fieldsteel, AH1
Levy, L1
Davidson, DE1
Johnsen, DO1
Tanticharoenyos, P1
Hickman, RL1
Kinnamon, KE1
Leiker, DL1
Banerjee, DK1
McDermott-Lancaster, RD1
Cook, RM1
González-Ruiz, A1
Haworth, SJ1
O'Neil, AB1
Warhurst, DC1
Clarkson, AB1
Williams, DE1
Rosenberg, C1
Gelber, RH1
Vischer, WA1
Browne, SG4
Rosenfeld, M2
Rees, RJ2
Freerksen, E1
Weddell, AG1
Ozawa, T1
Shepard, CC2
Karat, AB1
Yeary, RA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Neuroprotective Effect of Dapsone in Patients With Aneurysmal Subarachnoid Hemorrhage: Prospective, Randomized, Double-Blinded, Placebo-Controlled, Clinical Trial[NCT05131295]Phase 349 participants (Actual)Interventional2007-09-05Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

13 reviews available for dapsone and Disease Models, Animal

ArticleYear
Emerging Technologies to Target Drug Delivery to the Skin - the Role of Crystals and Carrier-Based Systems in the Case Study of Dapsone.
    Pharmaceutical research, 2020, Nov-09, Volume: 37, Issue:12

    Topics: Administration, Cutaneous; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemistry, Phar

2020
Dapsone in dermatology and beyond.
    Archives of dermatological research, 2014, Volume: 306, Issue:2

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Dapsone; Dermatology; Disea

2014
[Dermatitis herpetiformis: a review].
    Annales de dermatologie et de venereologie, 2011, Volume: 138, Issue:3

    Topics: Adult; Animals; Autoantibodies; Celiac Disease; Child; Combined Modality Therapy; Complement C3; Dap

2011
Epidermolysis bullosa acquisita.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2013, Volume: 27, Issue:10

    Topics: Adrenal Cortex Hormones; Animals; Antibodies, Monoclonal, Murine-Derived; Autoantibodies; Autoimmune

2013
Use of dapsone in the prevention and treatment of Pneumocystis carinii pneumonia: a review.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 27, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Clinical Trials as To

1998
[Progress in leprology in recent years].
    Vestnik dermatologii i venerologii, 1975, Issue:9

    Topics: Animals; Dapsone; Dihydroxyphenylalanine; Disease Models, Animal; Humans; L-Lactate Dehydrogenase; L

1975
Chemotherapy in Leprosy.
    International journal of dermatology, 1975, Volume: 14, Issue:4

    Topics: Acetamides; Anemia, Hemolytic; Aniline Compounds; Animals; Clofazimine; Dapsone; Disease Models, Ani

1975
The evaluation of present antileprosy compounds.
    Advances in pharmacology, 1969, Volume: 7

    Topics: Animals; Anti-Bacterial Agents; Clinical Trials as Topic; Dapsone; Disease Models, Animal; Drug Resi

1969
Recent advances in experimental leprosy.
    Bibliotheca tuberculosea, 1970, Volume: 26

    Topics: Africa; Animals; BCG Vaccine; Dapsone; Disease Models, Animal; Humans; Independent State of Samoa; I

1970
Summary of recent abstracts. 8. Leprosy.
    Tropical diseases bulletin, 1970, Volume: 67, Issue:9

    Topics: Animals; Antibody Formation; BCG Vaccine; Dapsone; Disease Models, Animal; Guinea Pigs; Humans; Lepr

1970
The evaluation of present antileprosy compounds.
    Advances in pharmacology and chemotherapy, 1969, Volume: 7

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; BCG Vaccine; Clinical Trials as Topic; Dapson

1969
Summary of recent abstracts. 8. Leprosy.
    Tropical diseases bulletin, 1971, Volume: 68, Issue:9

    Topics: Animals; Dapsone; Disease Models, Animal; Humans; Leprosy; Mice; Phenazines; Thalidomide

1971
The first decade in experimental leprosy.
    Bulletin of the World Health Organization, 1971, Volume: 44, Issue:6

    Topics: Animals; BCG Vaccine; Clofazimine; Dapsone; Disease Models, Animal; Drug Evaluation; Drug Evaluation

1971

Trials

2 trials available for dapsone and Disease Models, Animal

ArticleYear
The evaluation of present antileprosy compounds.
    Advances in pharmacology, 1969, Volume: 7

    Topics: Animals; Anti-Bacterial Agents; Clinical Trials as Topic; Dapsone; Disease Models, Animal; Drug Resi

1969
The evaluation of present antileprosy compounds.
    Advances in pharmacology and chemotherapy, 1969, Volume: 7

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; BCG Vaccine; Clinical Trials as Topic; Dapson

1969

Other Studies

43 other studies available for dapsone and Disease Models, Animal

ArticleYear
Discovery of FR115092: a novel antinephritic agent.
    Bioorganic & medicinal chemistry letters, 1998, Jan-06, Volume: 8, Issue:1

    Topics: Anemia; Animals; Disease Models, Animal; Male; Mice; Nephritis; Pyridines; Thiazoles

1998
Synthesis and effects of novel thiazole derivatives against thrombocytopenia.
    Bioorganic & medicinal chemistry letters, 1998, Sep-22, Volume: 8, Issue:18

    Topics: Animals; Autoantibodies; Blood Platelets; Dapsone; Disease Models, Animal; Dose-Response Relationshi

1998
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Dapsone Prevents Allodynia and Hyperalgesia and Decreased Oxidative Stress After Spinal Cord Injury in Rats.
    Spine, 2021, Oct-01, Volume: 46, Issue:19

    Topics: Animals; Dapsone; Disease Models, Animal; Hyperalgesia; Neuralgia; Oxidative Stress; Prospective Stu

2021
Protective effect of dapsone against bleomycin-induced lung fibrosis in rat.
    Experimental and molecular pathology, 2022, Volume: 124

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Bleomycin; Catalase; Dapsone; Disease Models, Anima

2022
The anti-inflammatory effect of dapsone on ovalbumin-induced allergic rhinitis in balb/c mice.
    Life sciences, 2022, May-15, Volume: 297

    Topics: Animals; Cytokines; Dapsone; Disease Models, Animal; Female; Mice; Mice, Inbred BALB C; Nasal Mucosa

2022
Dapsone prolong delayed excitotoxic neuronal cell death by interacting with proapoptotic/survival signaling proteins.
    Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 2020, Volume: 29, Issue:8

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Brain; Cells, Cultured; Dapsone; Disease Models,

2020
Pharmacoproteomic analysis of topical dapsone and prednisolone interventions in the aqueous humor of anterior uveitis.
    Experimental eye research, 2021, Volume: 206

    Topics: Administration, Topical; Animals; Anti-Infective Agents; Aqueous Humor; Dapsone; Disease Models, Ani

2021
Dapsone Ameliorates Colitis through TLR4/NF-kB Pathway in TNBS Induced Colitis Model in Rat.
    Archives of medical research, 2021, Volume: 52, Issue:6

    Topics: Animals; Colitis; Colon; Dapsone; Disease Models, Animal; Humans; NF-kappa B; Rats; Signal Transduct

2021
Dapsone Suppresses Disease in Preclinical Murine Models of Pemphigoid Diseases.
    The Journal of investigative dermatology, 2021, Volume: 141, Issue:11

    Topics: Animals; Cell Adhesion Molecules; Dapsone; Disease Models, Animal; Dose-Response Relationship, Drug;

2021
Carbon monoxide-bound red blood cell resuscitation ameliorates hepatic injury induced by massive hemorrhage and red blood cell resuscitation via hepatic cytochrome P450 protection in hemorrhagic shock rats.
    Journal of pharmaceutical sciences, 2014, Volume: 103, Issue:7

    Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dapsone; Disease Models, Animal; Erythrocy

2014
Diaminodiphenyl sulfone-induced parkin ameliorates age-dependent dopaminergic neuronal loss.
    Neurobiology of aging, 2016, Volume: 41

    Topics: Activating Transcription Factor 4; Aging; Animals; Anti-Inflammatory Agents; Brain; Cells, Cultured;

2016
Delayed administration of dapsone protects from tissue damage and improves recovery after spinal cord injury.
    Journal of neuroscience research, 2011, Volume: 89, Issue:3

    Topics: Animals; Dapsone; Disease Models, Animal; Female; Folic Acid Antagonists; Lipid Peroxidation; Motor

2011
Dapsone inhibits IL-8 secretion from human bronchial epithelial cells stimulated with lipopolysaccharide and resolves airway inflammation in the ferret.
    Chest, 2011, Volume: 140, Issue:4

    Topics: Administration, Oral; Aerosols; Animals; Anti-Inflammatory Agents; Bronchi; Bronchitis; Cell Surviva

2011
Neuroprotective effect of dapsone in an occlusive model of focal ischemia in rats.
    Brain research, 2004, Mar-05, Volume: 999, Issue:2

    Topics: Animals; Brain Infarction; Brain Ischemia; Dapsone; Disease Models, Animal; Dose-Response Relationsh

2004
A new model for dermatitis herpetiformis that uses HLA-DQ8 transgenic NOD mice.
    The Journal of clinical investigation, 2004, Volume: 114, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dapsone; Dermatitis Herpetiformis; Diet; Disease M

2004
Synthesis and antileprosy activity of some dialkyldithiocarbamates.
    The Journal of antimicrobial chemotherapy, 2006, Volume: 57, Issue:6

    Topics: Animals; Colony Count, Microbial; Dapsone; Disease Models, Animal; Drug Therapy, Combination; Humans

2006
Efficacy of diaminodiphenylsulfone and other drugs in murine Pneumocystis carinii pneumonitis.
    Antimicrobial agents and chemotherapy, 1984, Volume: 26, Issue:4

    Topics: Animals; Dapsone; Disease Models, Animal; Drug Combinations; Male; Pneumonia, Pneumocystis; Rats; Ra

1984
Leprosy today.
    The Australasian journal of dermatology, 1983, Volume: 24, Issue:2

    Topics: Clofazimine; Dapsone; Disease Models, Animal; Drug Resistance, Microbial; Humans; Leprosy; Mycobacte

1983
Multiple axonal myelination in the experimental mouse leprosy model.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1984, Volume: 52, Issue:2

    Topics: Animals; Axons; Dapsone; Disease Models, Animal; Female; Leprosy; Mice; Mycobacterium leprae; Nerve

1984
Relative potency of 10 drugs with anti-Pneumocystis carinii activity in an animal model.
    The Journal of infectious diseases, 1994, Volume: 170, Issue:4

    Topics: Animals; Anti-Infective Agents; Atovaquone; Azithromycin; Clarithromycin; Clindamycin; Clinical Tria

1994
Synergistic combinations of Ro 11-8958 and other dihydrofolate reductase inhibitors with sulfamethoxazole and dapsone for therapy of experimental pneumocystosis.
    Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:7

    Topics: AIDS-Related Opportunistic Infections; Animals; Dapsone; Disease Models, Animal; Dose-Response Relat

1993
Brown recluse spider envenomation of the eyelid: an animal model.
    Ophthalmic plastic and reconstructive surgery, 1995, Volume: 11, Issue:3

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antivenins; Combined Modality Therapy; Dap

1995
Direct comparison of antimalarial activity among PS-15 combination therapies by bioassay of serum samples from treated Saimiri sciureus.
    The Journal of parasitology, 1997, Volume: 83, Issue:3

    Topics: Animals; Antimalarials; Atovaquone; Biological Assay; Dapsone; Disease Models, Animal; Drug Synergis

1997
Experimental evaluation of roxithromycin combined with dapsone or sulphamethoxazole on Pneumocystis carinii and Toxoplasma gondii dual infections in a rat model.
    The Journal of antimicrobial chemotherapy, 1998, Volume: 41 Suppl B

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Dapsone; Disease Models, Animal; Dose-Respons

1998
Early behavioural changes in scrapie-affected mice and the influence of dapsone.
    The European journal of neuroscience, 2001, Volume: 14, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Avoidance Learning; Behavior, Animal; Body Weight;

2001
Dapsone-induced cholestasis and impairment of bile salt output in the rat.
    Biochemical pharmacology, 2002, Apr-15, Volume: 63, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bile Acids and Salts; Biomarkers; Body Weight; Car

2002
The anti-inflammatory profile of dapsone in animal models of inflammation.
    Agents and actions, 1978, Volume: 8, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental;

1978
Dapsone chemotherapy of Mycobacterium leprae infection of the neonatally thymectomized Lewis rat.
    The American journal of tropical medicine and hygiene, 1976, Volume: 25, Issue:6

    Topics: Animals; Animals, Newborn; Dapsone; Disease Models, Animal; Female; Leprosy; Male; Mice; Mice, Inbre

1976
Evaluating new antimalarial drugs against trophozoite induced Plasmodium cynomolgi malaria in rhesus monkeys.
    The American journal of tropical medicine and hygiene, 1976, Volume: 25, Issue:1

    Topics: Amodiaquine; Animals; Antimalarials; Dapsone; Disease Models, Animal; Dose-Response Relationship, Dr

1976
An experimental study to evaluate the bactericidal activity of ofloxacin against an established Mycobacterium leprae infection.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1992, Volume: 60, Issue:3

    Topics: Animals; Dapsone; Disease Models, Animal; Drug Therapy, Combination; Leprosy; Mice; Mice, Nude; Myco

1992
Eosinophil accumulation in rats injected with Sephadex particles.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1990, Volume: 20, Issue:5

    Topics: Animals; Dapsone; Dexamethasone; Dextrans; Disease Models, Animal; Eosinophilia; Eosinophils; Inject

1990
Dapsone in low doses prevents Pneumocystis carinii pneumonia in the rat model.
    The Journal of infection, 1991, Volume: 22, Issue:2

    Topics: Administration, Oral; Animals; Dapsone; Diet; Disease Models, Animal; Immune Tolerance; Male; Pneumo

1991
Efficacy of DL-alpha-difluoromethylornithine in a rat model of Pneumocystis carinii pneumonia.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:8

    Topics: Amphotericin B; Animals; Antiprotozoal Agents; Dapsone; Diminazene; Disease Models, Animal; Drug Com

1988
The neonatally thymectomized rat as a model of the lepromatous patient.
    International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1987, Volume: 55, Issue:4 Suppl

    Topics: Animals; Animals, Newborn; Dapsone; Disease Models, Animal; Humans; Immunotherapy; Leprosy; Mice; My

1987
[Comparative study on the effect of some clinically used sulfanilamide derivatives against toxoplasmosis in the mouse].
    Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Erste Abteilung Originale. Reihe A: Medizinische Mikrobiologie und Parasitologie, 1973, Volume: 223, Issue:2

    Topics: Aminobenzoates; Animals; Dapsone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Syn

1973
[Chemotherapy of so-called atypical mycobacterioses].
    Beitrage zur Klinik und Erforschung der Tuberkulose und der Lungenkrankheiten, 1968, Volume: 137, Issue:2

    Topics: Animals; Antitubercular Agents; Cycloserine; Dapsone; Disease Models, Animal; Drug Synergism; Ethamb

1968
Editorial: Prevention of leprosy.
    The Journal of tropical medicine and hygiene, 1974, Volume: 77, Issue:3

    Topics: Animals; Bacteriological Techniques; Body Temperature; Child; Dapsone; Disease Models, Animal; Human

1974
A new analogous model for the detection and evaluation of chemotherapeutic products effective in leprosy.
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:8

    Topics: Aniline Compounds; Animals; Dapsone; Disease Models, Animal; Drug Combinations; Ethionamide; Humans;

1972
Transmission of human leprosy to the mouse and its clinical implications.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1970, Volume: 64, Issue:1

    Topics: Animals; Communicable Diseases; Dapsone; Disease Models, Animal; Drug Resistance, Microbial; Hindlim

1970
Application of spectrophotofluorometric procedures to some problems in Mycobacterium leprae infections in mice and man treated with dapsone (DDS), diacetyl-DDS (DADDS), and di-formyl-DDS (DFD).
    The American journal of tropical medicine and hygiene, 1971, Volume: 20, Issue:2

    Topics: Acetates; Animals; Colorimetry; Dapsone; Disease Models, Animal; Fluorometry; Formates; Half-Life; H

1971
WHO expert committee on leprosy.
    World Health Organization technical report series, 1970, Volume: 459

    Topics: Attitude to Health; BCG Vaccine; Dapsone; Disability Evaluation; Disease Models, Animal; Health Educ

1970
Comparative toxicity studies on glucuronide-forming compounds in icteric and nonicteric newborn Gunn rats.
    The Journal of pediatrics, 1970, Volume: 77, Issue:1

    Topics: Aminobenzoates; Analgesics; Aniline Compounds; Animals; Animals, Newborn; Chloramphenicol; Dapsone;

1970