dapsone has been researched along with Cerebral Ischemia in 4 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study, the authors sought to define the differences in the incidence of delayed cerebral ischemia (DCI) between patients treated with dapsone and those treated with placebo." | 9.51 | Neuroprotective effect of dapsone in patients with aneurysmal subarachnoid hemorrhage: a prospective, randomized, double-blind, placebo-controlled clinical trial. ( Balcázar-Padrón, JC; Díaz-Ruíz, A; García-Pastor, C; Nathal, E; Navarro-Garcia de Llano, JP; Rios, C; Rodríguez-Hernandez, LA; Tristán-López, L, 2022) |
| " We have shown that dapsone acts as an antioxidant, antiinflammatory and antiapoptotic agent after brain Ischemia reperfusion (I/R) in rats; however, its therapeutic efficacy, measured by imaging has not been characterized." | 7.83 | Dapsone improves functional deficit and diminishes brain damage evaluated by 3-Tesla magnetic resonance image after transient cerebral ischemia and reperfusion in rats. ( Diaz-Ruiz, A; Heras-Romero, Y; Mendez-Armenta, M; Mondragón-Lozano, R; Nava-Ruiz, C; Ortiz-Plata, A; Osorio-Rico, L; Ríos, C; Roldan-Valadez, E, 2016) |
| "In this study, the authors sought to define the differences in the incidence of delayed cerebral ischemia (DCI) between patients treated with dapsone and those treated with placebo." | 5.51 | Neuroprotective effect of dapsone in patients with aneurysmal subarachnoid hemorrhage: a prospective, randomized, double-blind, placebo-controlled clinical trial. ( Balcázar-Padrón, JC; Díaz-Ruíz, A; García-Pastor, C; Nathal, E; Navarro-Garcia de Llano, JP; Rios, C; Rodríguez-Hernandez, LA; Tristán-López, L, 2022) |
| " Rats were dosed either with dapsone (12." | 5.35 | Antioxidant, antiinflammatory and antiapoptotic effects of dapsone in a model of brain ischemia/reperfusion in rats. ( Diaz-Ruiz, A; Montes, S; Nava-Ruiz, C; Orozco-Suarez, S; Ortiz-Plata, A; Pérez-Neri, I; Perez-Severiano, F; Ríos, C; Salgado-Ceballos, H; Zavala, C, 2008) |
| " We have shown that dapsone acts as an antioxidant, antiinflammatory and antiapoptotic agent after brain Ischemia reperfusion (I/R) in rats; however, its therapeutic efficacy, measured by imaging has not been characterized." | 3.83 | Dapsone improves functional deficit and diminishes brain damage evaluated by 3-Tesla magnetic resonance image after transient cerebral ischemia and reperfusion in rats. ( Diaz-Ruiz, A; Heras-Romero, Y; Mendez-Armenta, M; Mondragón-Lozano, R; Nava-Ruiz, C; Ortiz-Plata, A; Osorio-Rico, L; Ríos, C; Roldan-Valadez, E, 2016) |
| " Rats were dosed either with dapsone (12." | 1.35 | Antioxidant, antiinflammatory and antiapoptotic effects of dapsone in a model of brain ischemia/reperfusion in rats. ( Diaz-Ruiz, A; Montes, S; Nava-Ruiz, C; Orozco-Suarez, S; Ortiz-Plata, A; Pérez-Neri, I; Perez-Severiano, F; Ríos, C; Salgado-Ceballos, H; Zavala, C, 2008) |
| "Dapsone-treated animals showed a reduction of 93% (9." | 1.32 | Neuroprotective effect of dapsone in an occlusive model of focal ischemia in rats. ( Nader-Kawachi, J; Nava-Ruiz, C; Ríos, C; Rodriguez-Payán, AJ, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| García-Pastor, C | 1 |
| Navarro-Garcia de Llano, JP | 1 |
| Balcázar-Padrón, JC | 1 |
| Tristán-López, L | 1 |
| Rios, C | 4 |
| Díaz-Ruíz, A | 3 |
| Rodríguez-Hernandez, LA | 1 |
| Nathal, E | 1 |
| Roldan-Valadez, E | 1 |
| Ortiz-Plata, A | 2 |
| Mondragón-Lozano, R | 1 |
| Heras-Romero, Y | 1 |
| Mendez-Armenta, M | 1 |
| Osorio-Rico, L | 1 |
| Nava-Ruiz, C | 3 |
| Zavala, C | 1 |
| Montes, S | 1 |
| Salgado-Ceballos, H | 1 |
| Orozco-Suarez, S | 1 |
| Pérez-Neri, I | 1 |
| Perez-Severiano, F | 1 |
| Nader-Kawachi, J | 1 |
| Rodriguez-Payán, AJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Neuroprotective Effect of Dapsone in Patients With Aneurysmal Subarachnoid Hemorrhage: Prospective, Randomized, Double-Blinded, Placebo-Controlled, Clinical Trial[NCT05131295] | Phase 3 | 49 participants (Actual) | Interventional | 2007-09-05 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for dapsone and Cerebral Ischemia
| Article | Year |
|---|---|
Neuroprotective effect of dapsone in patients with aneurysmal subarachnoid hemorrhage: a prospective, randomized, double-blind, placebo-controlled clinical trial.
Topics: Adolescent; Adult; Aged; Brain Ischemia; Dapsone; Female; Humans; Male; Middle Aged; Neuroprotective | 2022 |
3 other studies available for dapsone and Cerebral Ischemia
| Article | Year |
|---|---|
Dapsone improves functional deficit and diminishes brain damage evaluated by 3-Tesla magnetic resonance image after transient cerebral ischemia and reperfusion in rats.
Topics: Animals; Brain; Brain Ischemia; Dapsone; Magnetic Resonance Imaging; Male; Neuroprotective Agents; N | 2016 |
Antioxidant, antiinflammatory and antiapoptotic effects of dapsone in a model of brain ischemia/reperfusion in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Brain Ischemia; Caspase 3; Caspase 9; Ch | 2008 |
Neuroprotective effect of dapsone in an occlusive model of focal ischemia in rats.
Topics: Animals; Brain Infarction; Brain Ischemia; Dapsone; Disease Models, Animal; Dose-Response Relationsh | 2004 |